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SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for FUBP1

Z-value: 0.42

Motif logo

Transcription factors associated with FUBP1

Gene Symbol Gene ID Gene Info
ENSG00000162613.12 far upstream element binding protein 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
FUBP1hg19_v2_chr1_-_78444776_784448000.941.1e-09Click!

Activity profile of FUBP1 motif

Sorted Z-values of FUBP1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr10_-_105845674 2.95 ENST00000353479.5
ENST00000369733.3
collagen, type XVII, alpha 1
chr10_-_105845536 2.44 ENST00000393211.3
collagen, type XVII, alpha 1
chr1_-_182360918 1.55 ENST00000339526.4
glutamate-ammonia ligase
chr6_-_56507586 1.53 ENST00000439203.1
ENST00000518935.1
ENST00000446842.2
ENST00000370765.6
ENST00000244364.6
dystonin
chr1_-_182360498 1.49 ENST00000417584.2
glutamate-ammonia ligase
chr1_+_209602771 1.36 ENST00000440276.1
MIR205 host gene (non-protein coding)
chr13_-_26795840 1.11 ENST00000381570.3
ENST00000399762.2
ENST00000346166.3
ring finger protein (C3H2C3 type) 6
chr6_-_56716686 1.01 ENST00000520645.1
dystonin
chr1_+_10290822 1.00 ENST00000377083.1
kinesin family member 1B
chr7_-_83824449 0.99 ENST00000420047.1
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr12_+_57522692 0.86 ENST00000554174.1
low density lipoprotein receptor-related protein 1
chr14_+_61654271 0.86 ENST00000555185.1
ENST00000557294.1
ENST00000556778.1
protein kinase C, eta
chr12_+_57522258 0.74 ENST00000553277.1
ENST00000243077.3
low density lipoprotein receptor-related protein 1
chr12_+_56324756 0.71 ENST00000331886.5
ENST00000555090.1
diacylglycerol kinase, alpha 80kDa
chr7_+_116166331 0.71 ENST00000393468.1
ENST00000393467.1
caveolin 1, caveolae protein, 22kDa
chr17_-_77005813 0.70 ENST00000590370.1
ENST00000591625.1
calcium activated nucleotidase 1
chr10_+_17686193 0.70 ENST00000377500.1
signal transducing adaptor molecule (SH3 domain and ITAM motif) 1
chr19_+_13134772 0.68 ENST00000587760.1
ENST00000585575.1
nuclear factor I/X (CCAAT-binding transcription factor)
chr2_-_216300784 0.63 ENST00000421182.1
ENST00000432072.2
ENST00000323926.6
ENST00000336916.4
ENST00000357867.4
ENST00000359671.1
ENST00000346544.3
ENST00000345488.5
ENST00000357009.2
ENST00000446046.1
ENST00000356005.4
ENST00000443816.1
ENST00000426059.1
ENST00000354785.4
fibronectin 1
chr8_+_102504979 0.62 ENST00000395927.1
grainyhead-like 2 (Drosophila)
chr12_+_14572070 0.61 ENST00000545769.1
ENST00000428217.2
ENST00000396279.2
ENST00000542514.1
ENST00000536279.1
activating transcription factor 7 interacting protein
chr12_+_57522439 0.60 ENST00000338962.4
low density lipoprotein receptor-related protein 1
chr4_+_89444961 0.59 ENST00000513325.1
HECT and RLD domain containing E3 ubiquitin protein ligase 3
chr1_+_31886653 0.59 ENST00000536384.1
serine incorporator 2
chr3_-_149510553 0.57 ENST00000462519.2
ENST00000446160.1
ENST00000383050.3
ankyrin repeat and ubiquitin domain containing 1
chr18_-_53255766 0.57 ENST00000566286.1
ENST00000564999.1
ENST00000566279.1
ENST00000354452.3
ENST00000356073.4
transcription factor 4
chr12_+_56324933 0.56 ENST00000549629.1
ENST00000555218.1
diacylglycerol kinase, alpha 80kDa
chr7_-_83824169 0.54 ENST00000265362.4
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr20_-_45981138 0.51 ENST00000446994.2
zinc finger, MYND-type containing 8
chr17_-_77005860 0.51 ENST00000591773.1
ENST00000588611.1
ENST00000586916.2
ENST00000592033.1
ENST00000588075.1
ENST00000302345.2
ENST00000591811.1
calcium activated nucleotidase 1
chr4_-_152149033 0.50 ENST00000514152.1
SH3 domain containing 19
chr4_-_99850243 0.50 ENST00000280892.6
ENST00000511644.1
ENST00000504432.1
ENST00000505992.1
eukaryotic translation initiation factor 4E
chr15_-_34628951 0.49 ENST00000397707.2
ENST00000560611.1
solute carrier family 12 (potassium/chloride transporter), member 6
chr9_+_128510454 0.49 ENST00000491787.3
ENST00000447726.2
pre-B-cell leukemia homeobox 3
chr10_+_98592674 0.48 ENST00000356016.3
ENST00000371097.4
ligand dependent nuclear receptor corepressor
chr2_-_208030295 0.47 ENST00000458272.1
Kruppel-like factor 7 (ubiquitous)
chr10_+_17686221 0.47 ENST00000540523.1
signal transducing adaptor molecule (SH3 domain and ITAM motif) 1
chr4_-_140544386 0.46 ENST00000561977.1
RP11-308D13.3
chr5_+_125706998 0.45 ENST00000506445.1
GRAM domain containing 3
chr19_+_10765614 0.45 ENST00000589283.1
interleukin enhancer binding factor 3, 90kDa
chr8_+_94929969 0.44 ENST00000517764.1
pyruvate dehyrogenase phosphatase catalytic subunit 1
chr6_-_131949305 0.43 ENST00000368053.4
ENST00000354577.4
ENST00000403834.3
ENST00000540546.1
ENST00000368068.3
ENST00000368060.3
mediator complex subunit 23
chr6_+_37897735 0.42 ENST00000373389.5
zinc finger, AN1-type domain 3
chr14_-_23762777 0.41 ENST00000431326.2
homeobox and leucine zipper encoding
chrX_+_102585124 0.41 ENST00000332431.4
ENST00000372666.1
transcription elongation factor A (SII)-like 7
chr10_-_65028817 0.41 ENST00000542921.1
jumonji domain containing 1C
chr12_-_26986076 0.41 ENST00000381340.3
inositol 1,4,5-trisphosphate receptor, type 2
chr11_+_34073195 0.41 ENST00000341394.4
cell cycle associated protein 1
chr3_-_187454281 0.41 ENST00000232014.4
B-cell CLL/lymphoma 6
chr5_+_145316120 0.40 ENST00000359120.4
SH3 domain containing ring finger 2
chr10_+_114710516 0.40 ENST00000542695.1
ENST00000346198.4
transcription factor 7-like 2 (T-cell specific, HMG-box)
chr12_-_85306594 0.40 ENST00000266682.5
solute carrier family 6 (neutral amino acid transporter), member 15
chr9_+_96846740 0.40 ENST00000288976.3
protein tyrosine phosphatase domain containing 1
chr11_-_47521309 0.39 ENST00000535982.1
CUGBP, Elav-like family member 1
chr3_-_182881595 0.37 ENST00000476015.1
lysosomal-associated membrane protein 3
chr11_-_46141338 0.37 ENST00000529782.1
ENST00000532010.1
ENST00000525438.1
ENST00000533757.1
ENST00000527782.1
PHD finger protein 21A
chr3_-_71632894 0.37 ENST00000493089.1
forkhead box P1
chr17_-_77005801 0.37 ENST00000392446.5
calcium activated nucleotidase 1
chr20_+_9049303 0.36 ENST00000407043.2
ENST00000441846.1
phospholipase C, beta 4
chr1_+_89149905 0.35 ENST00000316005.7
ENST00000370521.3
ENST00000370505.3
protein kinase N2
chr4_-_25865159 0.34 ENST00000502949.1
ENST00000264868.5
ENST00000513691.1
ENST00000514872.1
sel-1 suppressor of lin-12-like 3 (C. elegans)
chr12_-_57522813 0.34 ENST00000556155.1
signal transducer and activator of transcription 6, interleukin-4 induced
chr15_+_52155001 0.34 ENST00000544199.1
tropomodulin 3 (ubiquitous)
chrX_+_22050546 0.34 ENST00000379374.4
phosphate regulating endopeptidase homolog, X-linked
chr1_+_65613513 0.33 ENST00000395334.2
adenylate kinase 4
chr14_-_94547541 0.33 ENST00000544005.1
ENST00000555054.1
ENST00000330836.5
DEAD (Asp-Glu-Ala-Asp) box helicase 24
chr9_-_110251836 0.33 ENST00000374672.4
Kruppel-like factor 4 (gut)
chr4_+_170581213 0.32 ENST00000507875.1
chloride channel, voltage-sensitive 3
chr11_+_110001723 0.31 ENST00000528673.1
zinc finger CCCH-type containing 12C
chr1_+_43855545 0.31 ENST00000372450.4
ENST00000310739.4
seizure threshold 2 homolog (mouse)
chr6_-_111888474 0.31 ENST00000368735.1
TRAF3 interacting protein 2
chr21_+_30502806 0.31 ENST00000399928.1
ENST00000399926.1
MAP3K7 C-terminal like
chr14_-_24711865 0.31 ENST00000399423.4
ENST00000267415.7
TERF1 (TRF1)-interacting nuclear factor 2
chr11_+_18154059 0.31 ENST00000531264.1
MAS-related GPR, member X3
chrX_+_22056165 0.31 ENST00000535894.1
phosphate regulating endopeptidase homolog, X-linked
chr1_+_78383813 0.30 ENST00000342754.5
nexilin (F actin binding protein)
chr11_+_120207787 0.30 ENST00000397843.2
ENST00000356641.3
Rho guanine nucleotide exchange factor (GEF) 12
chr14_+_58797974 0.29 ENST00000417477.2
AT rich interactive domain 4A (RBP1-like)
chr10_+_17686124 0.28 ENST00000377524.3
signal transducing adaptor molecule (SH3 domain and ITAM motif) 1
chr2_+_33359687 0.28 ENST00000402934.1
ENST00000404525.1
ENST00000407925.1
latent transforming growth factor beta binding protein 1
chr1_-_40041925 0.28 ENST00000372862.3
poly(A) binding protein, cytoplasmic 4 (inducible form)
chr9_+_82186682 0.27 ENST00000376552.2
transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
chr13_+_49551020 0.26 ENST00000541916.1
fibronectin type III domain containing 3A
chr20_+_9049742 0.26 ENST00000437503.1
phospholipase C, beta 4
chr14_+_69658480 0.26 ENST00000409949.1
ENST00000409242.1
ENST00000312994.5
ENST00000413191.1
exonuclease 3'-5' domain containing 2
chr3_-_167452298 0.26 ENST00000475915.2
ENST00000462725.2
ENST00000461494.1
programmed cell death 10
chr10_-_91102410 0.24 ENST00000282673.4
lipase A, lysosomal acid, cholesterol esterase
chr5_+_173316341 0.24 ENST00000520867.1
ENST00000334035.5
cytoplasmic polyadenylation element binding protein 4
chr3_-_167452262 0.24 ENST00000487947.2
programmed cell death 10
chr2_+_33359646 0.24 ENST00000390003.4
ENST00000418533.2
latent transforming growth factor beta binding protein 1
chr20_+_9049682 0.23 ENST00000334005.3
ENST00000378473.3
phospholipase C, beta 4
chr4_-_153274078 0.22 ENST00000263981.5
F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
chr11_-_46142505 0.22 ENST00000524497.1
ENST00000418153.2
PHD finger protein 21A
chr1_+_2066252 0.21 ENST00000466352.1
protein kinase C, zeta
chr3_-_71114066 0.21 ENST00000485326.2
forkhead box P1
chr3_+_57875738 0.21 ENST00000417128.1
ENST00000438794.1
sarcolemma associated protein
chr16_-_69419473 0.20 ENST00000566750.1
telomeric repeat binding factor 2
chr15_-_59500973 0.20 ENST00000560749.1
myosin IE
chr2_-_65593784 0.19 ENST00000443619.2
sprouty-related, EVH1 domain containing 2
chr2_+_33359473 0.18 ENST00000432635.1
latent transforming growth factor beta binding protein 1
chr2_+_162087577 0.18 ENST00000439442.1
TRAF family member-associated NFKB activator
chr7_-_87849340 0.18 ENST00000419179.1
ENST00000265729.2
sorcin
chr5_+_36608280 0.18 ENST00000513646.1
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr14_-_24711806 0.17 ENST00000540705.1
ENST00000538777.1
ENST00000558566.1
ENST00000559019.1
TERF1 (TRF1)-interacting nuclear factor 2
chr19_+_11546093 0.17 ENST00000591462.1
protein kinase C substrate 80K-H
chr8_-_116680833 0.17 ENST00000220888.5
trichorhinophalangeal syndrome I
chr18_-_53255379 0.17 ENST00000565908.2
transcription factor 4
chr2_+_181845763 0.16 ENST00000602499.1
ubiquitin-conjugating enzyme E2E 3
chr1_+_43855560 0.16 ENST00000562955.1
seizure threshold 2 homolog (mouse)
chr1_-_161207986 0.16 ENST00000506209.1
ENST00000367980.2
nuclear receptor subfamily 1, group I, member 3
chr5_-_115872142 0.15 ENST00000510263.1
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
chr12_-_46766577 0.15 ENST00000256689.5
solute carrier family 38, member 2
chrX_+_95939638 0.14 ENST00000373061.3
ENST00000373054.4
ENST00000355827.4
diaphanous-related formin 2
chr2_+_201980827 0.14 ENST00000309955.3
ENST00000443227.1
ENST00000341222.6
ENST00000355558.4
ENST00000340870.5
ENST00000341582.6
CASP8 and FADD-like apoptosis regulator
chr5_+_72509751 0.14 ENST00000515556.1
ENST00000513379.1
ENST00000427584.2
RP11-60A8.1
chr9_+_135457530 0.14 ENST00000263610.2
BarH-like homeobox 1
chr11_+_111473108 0.14 ENST00000304987.3
salt-inducible kinase 2
chr1_-_161208013 0.13 ENST00000515452.1
ENST00000367983.4
nuclear receptor subfamily 1, group I, member 3
chr5_+_140027355 0.13 ENST00000417647.2
ENST00000507593.1
ENST00000508301.1
IK cytokine, down-regulator of HLA II
chr3_+_186383741 0.13 ENST00000232003.4
histidine-rich glycoprotein
chr7_-_127032114 0.13 ENST00000436992.1
zinc finger protein 800
chr4_-_100242549 0.12 ENST00000305046.8
ENST00000394887.3
alcohol dehydrogenase 1B (class I), beta polypeptide
chr16_+_81070792 0.12 ENST00000564241.1
ENST00000565237.1
ATM interactor
chr4_-_186578674 0.12 ENST00000438278.1
sorbin and SH3 domain containing 2
chr3_-_47950745 0.12 ENST00000429422.1
microtubule-associated protein 4
chr17_-_76713100 0.11 ENST00000585509.1
cytohesin 1
chr1_+_202317815 0.11 ENST00000608999.1
ENST00000336894.4
ENST00000480184.1
protein phosphatase 1, regulatory subunit 12B
chr3_+_19988566 0.11 ENST00000273047.4
RAB5A, member RAS oncogene family
chr5_-_159846399 0.10 ENST00000297151.4
SLU7 splicing factor homolog (S. cerevisiae)
chr4_+_90033968 0.09 ENST00000317005.2
tigger transposable element derived 2
chr16_-_3350614 0.09 ENST00000268674.2
tigger transposable element derived 7
chr5_-_88179017 0.09 ENST00000514028.1
ENST00000514015.1
ENST00000503075.1
ENST00000437473.2
myocyte enhancer factor 2C
chr9_-_113761720 0.09 ENST00000541779.1
ENST00000374430.2
lysophosphatidic acid receptor 1
chr5_-_1882858 0.08 ENST00000511126.1
ENST00000231357.2
iroquois homeobox 4
chr17_+_75369400 0.08 ENST00000590059.1
septin 9
chr8_-_120685608 0.08 ENST00000427067.2
ectonucleotide pyrophosphatase/phosphodiesterase 2
chr6_+_121756809 0.08 ENST00000282561.3
gap junction protein, alpha 1, 43kDa
chr7_-_144533074 0.07 ENST00000360057.3
ENST00000378099.3
thiamin pyrophosphokinase 1
chr3_-_193272874 0.07 ENST00000342695.4
ATPase type 13A4
chr19_-_55453077 0.07 ENST00000328092.5
ENST00000590030.1
NLR family, pyrin domain containing 7
chr1_-_154178803 0.07 ENST00000368525.3
chromosome 1 open reading frame 189
chr4_-_2420335 0.06 ENST00000503000.1
zinc finger, FYVE domain containing 28
chr15_-_55657428 0.06 ENST00000568543.1
cell cycle progression 1
chr9_+_4662282 0.06 ENST00000381883.2
phosphatidic acid phosphatase type 2 domain containing 2
chr11_-_46142615 0.06 ENST00000529734.1
ENST00000323180.6
PHD finger protein 21A
chr12_-_22094336 0.06 ENST00000326684.4
ATP-binding cassette, sub-family C (CFTR/MRP), member 9
chr21_+_17791648 0.06 ENST00000602892.1
ENST00000418813.2
ENST00000435697.1
long intergenic non-protein coding RNA 478
chr4_+_177796841 0.06 ENST00000508790.1
RP11-765K14.1
chr11_-_111741994 0.06 ENST00000398006.2
ALG9, alpha-1,2-mannosyltransferase
chr1_+_218519577 0.05 ENST00000366930.4
ENST00000366929.4
transforming growth factor, beta 2
chr2_-_26205550 0.05 ENST00000405914.1
kinesin family member 3C
chr18_+_7754957 0.05 ENST00000400053.4
protein tyrosine phosphatase, receptor type, M
chr5_-_88178964 0.05 ENST00000513252.1
ENST00000508569.1
ENST00000510942.1
ENST00000506554.1
myocyte enhancer factor 2C
chr6_-_31612808 0.05 ENST00000438149.1
BCL2-associated athanogene 6
chr12_+_10365404 0.05 ENST00000266458.5
ENST00000421801.2
ENST00000544284.1
ENST00000545047.1
ENST00000543602.1
ENST00000545887.1
GABA(A) receptor-associated protein like 1
chr19_+_10765003 0.05 ENST00000407004.3
ENST00000589998.1
ENST00000589600.1
interleukin enhancer binding factor 3, 90kDa
chr19_-_19302931 0.05 ENST00000444486.3
ENST00000514819.3
ENST00000585679.1
ENST00000162023.5
MEF2BNB-MEF2B readthrough
MEF2B neighbor
myocyte enhancer factor 2B
chr16_+_24741013 0.04 ENST00000315183.7
ENST00000395799.3
trinucleotide repeat containing 6A
chr5_-_157161727 0.04 ENST00000599823.1
Uncharacterized protein
chrX_-_33146477 0.04 ENST00000378677.2
dystrophin
chr15_+_38276910 0.04 ENST00000558081.2
RP11-1008C21.1
chr12_+_111374375 0.04 ENST00000553177.1
ENST00000548368.1
ENST00000331096.2
ENST00000547607.1
RP1-46F2.2
chr9_+_116173000 0.03 ENST00000288462.4
chromosome 9 open reading frame 43
chr14_+_65878650 0.03 ENST00000555559.1
fucosyltransferase 8 (alpha (1,6) fucosyltransferase)
chr9_+_75766763 0.02 ENST00000456643.1
ENST00000415424.1
annexin A1
chr7_-_22234381 0.02 ENST00000458533.1
Rap guanine nucleotide exchange factor (GEF) 5
chr7_-_22233442 0.02 ENST00000401957.2
Rap guanine nucleotide exchange factor (GEF) 5
chr1_-_155271213 0.02 ENST00000342741.4
pyruvate kinase, liver and RBC
chr1_+_84609944 0.01 ENST00000370685.3
protein kinase, cAMP-dependent, catalytic, beta
chr12_-_22094159 0.01 ENST00000538350.1
ATP-binding cassette, sub-family C (CFTR/MRP), member 9
chrX_-_65259914 0.01 ENST00000374737.4
ENST00000455586.2
V-set and immunoglobulin domain containing 4
chrX_+_9935392 0.01 ENST00000445307.2
Homo sapiens uncharacterized LOC100288814 (LOC100288814), mRNA.
chr9_+_97562440 0.01 ENST00000395357.2
chromosome 9 open reading frame 3
chr1_-_27701307 0.01 ENST00000270879.4
ENST00000354982.2
ficolin (collagen/fibrinogen domain containing) 3
chr7_+_35756400 0.00 ENST00000585952.1
AC018647.3
chr13_+_49684445 0.00 ENST00000398316.3
fibronectin type III domain containing 3A
chr1_-_248005254 0.00 ENST00000355784.2
olfactory receptor, family 11, subfamily L, member 1

Network of associatons between targets according to the STRING database.

First level regulatory network of FUBP1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 3.0 GO:0006542 glutamine biosynthetic process(GO:0006542)
0.4 2.2 GO:1905167 positive regulation of lysosomal protein catabolic process(GO:1905167)
0.4 1.5 GO:1903045 neural crest cell migration involved in sympathetic nervous system development(GO:1903045)
0.3 1.1 GO:0044314 protein K27-linked ubiquitination(GO:0044314)
0.3 1.0 GO:1904647 response to rotenone(GO:1904647)
0.2 0.7 GO:1900085 negative regulation of peptidyl-tyrosine autophosphorylation(GO:1900085) negative regulation of inward rectifier potassium channel activity(GO:1903609)
0.2 0.6 GO:1904235 regulation of substrate-dependent cell migration, cell attachment to substrate(GO:1904235) positive regulation of substrate-dependent cell migration, cell attachment to substrate(GO:1904237)
0.2 0.5 GO:0007388 anterior compartment pattern formation(GO:0007387) posterior compartment specification(GO:0007388)
0.2 1.4 GO:1903551 regulation of extracellular exosome assembly(GO:1903551)
0.2 2.5 GO:0008090 retrograde axonal transport(GO:0008090)
0.1 5.4 GO:0031581 hemidesmosome assembly(GO:0031581)
0.1 0.6 GO:1904383 response to sodium phosphate(GO:1904383)
0.1 0.4 GO:0032764 negative regulation of mast cell cytokine production(GO:0032764) negative regulation of isotype switching to IgE isotypes(GO:0048294)
0.1 0.6 GO:1904219 regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) positive regulation of serine C-palmitoyltransferase activity(GO:1904222)
0.1 0.5 GO:0071477 hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
0.1 0.6 GO:0072619 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.1 0.6 GO:0060671 epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
0.1 0.5 GO:1903588 negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903588)
0.1 0.3 GO:2000342 negative regulation of chemokine (C-X-C motif) ligand 2 production(GO:2000342)
0.1 0.9 GO:0034350 regulation of glial cell apoptotic process(GO:0034350) negative regulation of glial cell apoptotic process(GO:0034351)
0.1 0.3 GO:0002296 T-helper 1 cell lineage commitment(GO:0002296)
0.1 0.5 GO:1901668 regulation of superoxide dismutase activity(GO:1901668)
0.1 0.7 GO:0035583 sequestering of TGFbeta in extracellular matrix(GO:0035583)
0.1 0.5 GO:0010836 negative regulation of protein ADP-ribosylation(GO:0010836)
0.1 0.5 GO:1902952 positive regulation of dendritic spine maintenance(GO:1902952) regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903756) negative regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903758)
0.1 0.3 GO:0048388 endosomal lumen acidification(GO:0048388)
0.0 0.4 GO:0048625 regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334) myoblast fate commitment(GO:0048625) positive regulation of proteoglycan biosynthetic process(GO:1902730)
0.0 0.2 GO:1903517 regulation of telomere maintenance via recombination(GO:0032207) negative regulation of telomere maintenance via recombination(GO:0032208) regulation of single strand break repair(GO:1903516) negative regulation of single strand break repair(GO:1903517) negative regulation of beta-galactosidase activity(GO:1903770) telomere single strand break repair(GO:1903823) negative regulation of telomere single strand break repair(GO:1903824)
0.0 0.3 GO:0097368 establishment of Sertoli cell barrier(GO:0097368)
0.0 0.2 GO:2000639 regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
0.0 0.1 GO:2001027 negative regulation of endothelial cell chemotaxis(GO:2001027)
0.0 1.3 GO:0046339 diacylglycerol metabolic process(GO:0046339)
0.0 0.4 GO:0015820 leucine transport(GO:0015820)
0.0 0.3 GO:0046940 nucleoside monophosphate phosphorylation(GO:0046940)
0.0 0.3 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.0 0.2 GO:0035166 post-embryonic hemopoiesis(GO:0035166)
0.0 0.5 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.0 0.2 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.0 0.3 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.0 0.4 GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
0.0 0.2 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.0 0.2 GO:0097577 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.0 0.2 GO:1903367 positive regulation of fear response(GO:1903367) positive regulation of behavioral fear response(GO:2000987)
0.0 0.6 GO:0045898 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.0 0.1 GO:0003275 apoptotic process involved in outflow tract morphogenesis(GO:0003275) uterine wall breakdown(GO:0042704) positive regulation of catagen(GO:0051795) regulation of apoptotic process involved in outflow tract morphogenesis(GO:1902256)
0.0 0.1 GO:2000286 receptor internalization involved in canonical Wnt signaling pathway(GO:2000286)
0.0 0.2 GO:2001181 positive regulation of interleukin-10 secretion(GO:2001181)
0.0 0.1 GO:1904566 response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566)
0.0 0.1 GO:0051012 microtubule sliding(GO:0051012)
0.0 0.2 GO:0070779 gamma-aminobutyric acid biosynthetic process(GO:0009449) D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.0 0.3 GO:0060009 Sertoli cell development(GO:0060009)
0.0 0.4 GO:0071361 cellular response to ethanol(GO:0071361)
0.0 0.2 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.0 0.4 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.0 1.4 GO:0030166 proteoglycan biosynthetic process(GO:0030166)
0.0 0.3 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.0 0.2 GO:0032328 alanine transport(GO:0032328)
0.0 0.4 GO:0016246 RNA interference(GO:0016246)
0.0 0.1 GO:1903944 regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.0 0.4 GO:0035455 response to interferon-alpha(GO:0035455)
0.0 0.1 GO:2001106 regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.5 GO:0031673 H zone(GO:0031673)
0.2 5.4 GO:0030056 hemidesmosome(GO:0030056)
0.2 1.4 GO:0033565 ESCRT-0 complex(GO:0033565)
0.1 3.0 GO:0097386 glial cell projection(GO:0097386)
0.1 0.4 GO:0097232 lamellar body membrane(GO:0097232) alveolar lamellar body membrane(GO:0097233)
0.1 0.5 GO:0010370 perinucleolar chromocenter(GO:0010370)
0.1 0.5 GO:1990130 Iml1 complex(GO:1990130)
0.0 0.4 GO:0071664 beta-catenin-TCF7L2 complex(GO:0070369) catenin-TCF7L2 complex(GO:0071664)
0.0 0.6 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.7 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.0 0.2 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.0 0.5 GO:0033391 chromatoid body(GO:0033391)
0.0 0.7 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.0 0.2 GO:0044326 dendritic spine neck(GO:0044326)
0.0 1.1 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.0 0.2 GO:0070187 telosome(GO:0070187)
0.0 1.6 GO:0035580 specific granule lumen(GO:0035580)
0.0 0.4 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.0 1.0 GO:1904115 axon cytoplasm(GO:1904115)
0.0 2.2 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 0.2 GO:0045179 apical cortex(GO:0045179)
0.0 0.2 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.1 GO:0098559 cytoplasmic side of early endosome membrane(GO:0098559)
0.0 0.1 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 3.0 GO:0016211 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.7 2.2 GO:0016964 alpha-2 macroglobulin receptor activity(GO:0016964)
0.3 1.6 GO:0004382 guanosine-diphosphatase activity(GO:0004382)
0.2 0.7 GO:0070320 inward rectifier potassium channel inhibitor activity(GO:0070320)
0.1 0.4 GO:0005298 proline:sodium symporter activity(GO:0005298)
0.1 0.9 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.1 0.7 GO:0050436 microfibril binding(GO:0050436)
0.1 0.4 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.1 0.3 GO:0017130 poly(C) RNA binding(GO:0017130)
0.1 1.5 GO:0030215 semaphorin receptor binding(GO:0030215)
0.1 0.4 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.1 0.3 GO:0046899 nucleoside triphosphate adenylate kinase activity(GO:0046899)
0.1 2.5 GO:0051010 microtubule plus-end binding(GO:0051010)
0.1 0.3 GO:0001010 transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010)
0.1 0.3 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.0 0.5 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.0 0.4 GO:0042835 BRE binding(GO:0042835)
0.0 0.3 GO:0004882 androgen receptor activity(GO:0004882)
0.0 1.3 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.2 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.0 1.0 GO:0044213 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.0 0.5 GO:0022820 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.0 0.7 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 0.6 GO:0015194 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0 0.2 GO:0004771 sterol esterase activity(GO:0004771)
0.0 0.3 GO:0008310 single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
0.0 0.2 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.0 0.9 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 0.4 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 0.1 GO:0000386 second spliceosomal transesterification activity(GO:0000386)
0.0 0.6 GO:0004697 protein kinase C activity(GO:0004697)
0.0 0.1 GO:0008281 sulfonylurea receptor activity(GO:0008281)
0.0 0.2 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.0 1.7 GO:0050681 androgen receptor binding(GO:0050681)
0.0 0.2 GO:0097027 ubiquitin-protein transferase activator activity(GO:0097027)
0.0 0.1 GO:0047391 alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391)
0.0 0.4 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.1 GO:0000026 alpha-1,2-mannosyltransferase activity(GO:0000026)
0.0 0.2 GO:0003964 telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.0 0.1 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.0 1.0 GO:1990939 ATP-dependent microtubule motor activity(GO:1990939)
0.0 0.1 GO:0004024 alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
0.0 0.5 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.6 GO:0016504 peptidase activator activity(GO:0016504)
0.0 0.3 GO:0005523 tropomyosin binding(GO:0005523)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 5.2 NABA COLLAGENS Genes encoding collagen proteins
0.0 2.8 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 2.5 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.3 SIG IL4RECEPTOR IN B LYPHOCYTES Genes related to IL4 rceptor signaling in B lymphocytes
0.0 0.7 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.0 1.5 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 1.1 ST G ALPHA I PATHWAY G alpha i Pathway
0.0 0.9 PID ENDOTHELIN PATHWAY Endothelins
0.0 1.3 PID IL2 1PATHWAY IL2-mediated signaling events
0.0 0.4 PID RHOA PATHWAY RhoA signaling pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.0 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.1 5.4 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.1 1.5 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 2.5 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 1.4 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.4 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.5 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 0.6 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.8 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.6 REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.0 0.4 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.3 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 0.7 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends