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SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for FUBP1

Z-value: 0.42

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Transcription factors associated with FUBP1

Gene Symbol Gene ID Gene Info
FUBP1
ENSG00000162613.12 far upstream element binding protein 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
FUBP1hg19_v2_chr1_-_78444776_784448000.941.1e-09Click!

Activity profile of FUBP1 motif

Sorted Z-values of FUBP1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr10_-_105845674 2.95 ENST00000353479.5
ENST00000369733.3
COL17A1
collagen, type XVII, alpha 1
chr10_-_105845536 2.44 ENST00000393211.3
COL17A1
collagen, type XVII, alpha 1
chr1_-_182360918 1.55 ENST00000339526.4
GLUL
glutamate-ammonia ligase
chr6_-_56507586 1.53 ENST00000439203.1
ENST00000518935.1
ENST00000446842.2
ENST00000370765.6
ENST00000244364.6
DST
dystonin
chr1_-_182360498 1.49 ENST00000417584.2
GLUL
glutamate-ammonia ligase
chr1_+_209602771 1.36 ENST00000440276.1
MIR205HG
MIR205 host gene (non-protein coding)
chr13_-_26795840 1.11 ENST00000381570.3
ENST00000399762.2
ENST00000346166.3
RNF6
ring finger protein (C3H2C3 type) 6
chr6_-_56716686 1.01 ENST00000520645.1
DST
dystonin
chr1_+_10290822 1.00 ENST00000377083.1
KIF1B
kinesin family member 1B
chr7_-_83824449 0.99 ENST00000420047.1
SEMA3A
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr12_+_57522692 0.86 ENST00000554174.1
LRP1
low density lipoprotein receptor-related protein 1
chr14_+_61654271 0.86 ENST00000555185.1
ENST00000557294.1
ENST00000556778.1
PRKCH
protein kinase C, eta
chr12_+_57522258 0.74 ENST00000553277.1
ENST00000243077.3
LRP1
low density lipoprotein receptor-related protein 1
chr12_+_56324756 0.71 ENST00000331886.5
ENST00000555090.1
DGKA
diacylglycerol kinase, alpha 80kDa
chr7_+_116166331 0.71 ENST00000393468.1
ENST00000393467.1
CAV1
caveolin 1, caveolae protein, 22kDa
chr17_-_77005813 0.70 ENST00000590370.1
ENST00000591625.1
CANT1
calcium activated nucleotidase 1
chr10_+_17686193 0.70 ENST00000377500.1
STAM
signal transducing adaptor molecule (SH3 domain and ITAM motif) 1
chr19_+_13134772 0.68 ENST00000587760.1
ENST00000585575.1
NFIX
nuclear factor I/X (CCAAT-binding transcription factor)
chr2_-_216300784 0.63 ENST00000421182.1
ENST00000432072.2
ENST00000323926.6
ENST00000336916.4
ENST00000357867.4
ENST00000359671.1
ENST00000346544.3
ENST00000345488.5
ENST00000357009.2
ENST00000446046.1
ENST00000356005.4
ENST00000443816.1
ENST00000426059.1
ENST00000354785.4
FN1
fibronectin 1
chr8_+_102504979 0.62 ENST00000395927.1
GRHL2
grainyhead-like 2 (Drosophila)
chr12_+_14572070 0.61 ENST00000545769.1
ENST00000428217.2
ENST00000396279.2
ENST00000542514.1
ENST00000536279.1
ATF7IP
activating transcription factor 7 interacting protein
chr12_+_57522439 0.60 ENST00000338962.4
LRP1
low density lipoprotein receptor-related protein 1
chr4_+_89444961 0.59 ENST00000513325.1
HERC3
HECT and RLD domain containing E3 ubiquitin protein ligase 3
chr1_+_31886653 0.59 ENST00000536384.1
SERINC2
serine incorporator 2
chr3_-_149510553 0.57 ENST00000462519.2
ENST00000446160.1
ENST00000383050.3
ANKUB1
ankyrin repeat and ubiquitin domain containing 1
chr18_-_53255766 0.57 ENST00000566286.1
ENST00000564999.1
ENST00000566279.1
ENST00000354452.3
ENST00000356073.4
TCF4
transcription factor 4
chr12_+_56324933 0.56 ENST00000549629.1
ENST00000555218.1
DGKA
diacylglycerol kinase, alpha 80kDa
chr7_-_83824169 0.54 ENST00000265362.4
SEMA3A
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr20_-_45981138 0.51 ENST00000446994.2
ZMYND8
zinc finger, MYND-type containing 8
chr17_-_77005860 0.51 ENST00000591773.1
ENST00000588611.1
ENST00000586916.2
ENST00000592033.1
ENST00000588075.1
ENST00000302345.2
ENST00000591811.1
CANT1
calcium activated nucleotidase 1
chr4_-_152149033 0.50 ENST00000514152.1
SH3D19
SH3 domain containing 19
chr4_-_99850243 0.50 ENST00000280892.6
ENST00000511644.1
ENST00000504432.1
ENST00000505992.1
EIF4E
eukaryotic translation initiation factor 4E
chr15_-_34628951 0.49 ENST00000397707.2
ENST00000560611.1
SLC12A6
solute carrier family 12 (potassium/chloride transporter), member 6
chr9_+_128510454 0.49 ENST00000491787.3
ENST00000447726.2
PBX3
pre-B-cell leukemia homeobox 3
chr10_+_98592674 0.48 ENST00000356016.3
ENST00000371097.4
LCOR
ligand dependent nuclear receptor corepressor
chr2_-_208030295 0.47 ENST00000458272.1
KLF7
Kruppel-like factor 7 (ubiquitous)
chr10_+_17686221 0.47 ENST00000540523.1
STAM
signal transducing adaptor molecule (SH3 domain and ITAM motif) 1
chr4_-_140544386 0.46 ENST00000561977.1
RP11-308D13.3
RP11-308D13.3
chr5_+_125706998 0.45 ENST00000506445.1
GRAMD3
GRAM domain containing 3
chr19_+_10765614 0.45 ENST00000589283.1
ILF3
interleukin enhancer binding factor 3, 90kDa
chr8_+_94929969 0.44 ENST00000517764.1
PDP1
pyruvate dehyrogenase phosphatase catalytic subunit 1
chr6_-_131949305 0.43 ENST00000368053.4
ENST00000354577.4
ENST00000403834.3
ENST00000540546.1
ENST00000368068.3
ENST00000368060.3
MED23
mediator complex subunit 23
chr6_+_37897735 0.42 ENST00000373389.5
ZFAND3
zinc finger, AN1-type domain 3
chr14_-_23762777 0.41 ENST00000431326.2
HOMEZ
homeobox and leucine zipper encoding
chrX_+_102585124 0.41 ENST00000332431.4
ENST00000372666.1
TCEAL7
transcription elongation factor A (SII)-like 7
chr10_-_65028817 0.41 ENST00000542921.1
JMJD1C
jumonji domain containing 1C
chr12_-_26986076 0.41 ENST00000381340.3
ITPR2
inositol 1,4,5-trisphosphate receptor, type 2
chr11_+_34073195 0.41 ENST00000341394.4
CAPRIN1
cell cycle associated protein 1
chr3_-_187454281 0.41 ENST00000232014.4
BCL6
B-cell CLL/lymphoma 6
chr5_+_145316120 0.40 ENST00000359120.4
SH3RF2
SH3 domain containing ring finger 2
chr10_+_114710516 0.40 ENST00000542695.1
ENST00000346198.4
TCF7L2
transcription factor 7-like 2 (T-cell specific, HMG-box)
chr12_-_85306594 0.40 ENST00000266682.5
SLC6A15
solute carrier family 6 (neutral amino acid transporter), member 15
chr9_+_96846740 0.40 ENST00000288976.3
PTPDC1
protein tyrosine phosphatase domain containing 1
chr11_-_47521309 0.39 ENST00000535982.1
CELF1
CUGBP, Elav-like family member 1
chr3_-_182881595 0.37 ENST00000476015.1
LAMP3
lysosomal-associated membrane protein 3
chr11_-_46141338 0.37 ENST00000529782.1
ENST00000532010.1
ENST00000525438.1
ENST00000533757.1
ENST00000527782.1
PHF21A
PHD finger protein 21A
chr3_-_71632894 0.37 ENST00000493089.1
FOXP1
forkhead box P1
chr17_-_77005801 0.37 ENST00000392446.5
CANT1
calcium activated nucleotidase 1
chr20_+_9049303 0.36 ENST00000407043.2
ENST00000441846.1
PLCB4
phospholipase C, beta 4
chr1_+_89149905 0.35 ENST00000316005.7
ENST00000370521.3
ENST00000370505.3
PKN2
protein kinase N2
chr4_-_25865159 0.34 ENST00000502949.1
ENST00000264868.5
ENST00000513691.1
ENST00000514872.1
SEL1L3
sel-1 suppressor of lin-12-like 3 (C. elegans)
chr12_-_57522813 0.34 ENST00000556155.1
STAT6
signal transducer and activator of transcription 6, interleukin-4 induced
chr15_+_52155001 0.34 ENST00000544199.1
TMOD3
tropomodulin 3 (ubiquitous)
chrX_+_22050546 0.34 ENST00000379374.4
PHEX
phosphate regulating endopeptidase homolog, X-linked
chr1_+_65613513 0.33 ENST00000395334.2
AK4
adenylate kinase 4
chr14_-_94547541 0.33 ENST00000544005.1
ENST00000555054.1
ENST00000330836.5
DDX24
DEAD (Asp-Glu-Ala-Asp) box helicase 24
chr9_-_110251836 0.33 ENST00000374672.4
KLF4
Kruppel-like factor 4 (gut)
chr4_+_170581213 0.32 ENST00000507875.1
CLCN3
chloride channel, voltage-sensitive 3
chr11_+_110001723 0.31 ENST00000528673.1
ZC3H12C
zinc finger CCCH-type containing 12C
chr1_+_43855545 0.31 ENST00000372450.4
ENST00000310739.4
SZT2
seizure threshold 2 homolog (mouse)
chr6_-_111888474 0.31 ENST00000368735.1
TRAF3IP2
TRAF3 interacting protein 2
chr21_+_30502806 0.31 ENST00000399928.1
ENST00000399926.1
MAP3K7CL
MAP3K7 C-terminal like
chr14_-_24711865 0.31 ENST00000399423.4
ENST00000267415.7
TINF2
TERF1 (TRF1)-interacting nuclear factor 2
chr11_+_18154059 0.31 ENST00000531264.1
MRGPRX3
MAS-related GPR, member X3
chrX_+_22056165 0.31 ENST00000535894.1
PHEX
phosphate regulating endopeptidase homolog, X-linked
chr1_+_78383813 0.30 ENST00000342754.5
NEXN
nexilin (F actin binding protein)
chr11_+_120207787 0.30 ENST00000397843.2
ENST00000356641.3
ARHGEF12
Rho guanine nucleotide exchange factor (GEF) 12
chr14_+_58797974 0.29 ENST00000417477.2
ARID4A
AT rich interactive domain 4A (RBP1-like)
chr10_+_17686124 0.28 ENST00000377524.3
STAM
signal transducing adaptor molecule (SH3 domain and ITAM motif) 1
chr2_+_33359687 0.28 ENST00000402934.1
ENST00000404525.1
ENST00000407925.1
LTBP1
latent transforming growth factor beta binding protein 1
chr1_-_40041925 0.28 ENST00000372862.3
PABPC4
poly(A) binding protein, cytoplasmic 4 (inducible form)
chr9_+_82186682 0.27 ENST00000376552.2
TLE4
transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
chr13_+_49551020 0.26 ENST00000541916.1
FNDC3A
fibronectin type III domain containing 3A
chr20_+_9049742 0.26 ENST00000437503.1
PLCB4
phospholipase C, beta 4
chr14_+_69658480 0.26 ENST00000409949.1
ENST00000409242.1
ENST00000312994.5
ENST00000413191.1
EXD2
exonuclease 3'-5' domain containing 2
chr3_-_167452298 0.26 ENST00000475915.2
ENST00000462725.2
ENST00000461494.1
PDCD10
programmed cell death 10
chr10_-_91102410 0.24 ENST00000282673.4
LIPA
lipase A, lysosomal acid, cholesterol esterase
chr5_+_173316341 0.24 ENST00000520867.1
ENST00000334035.5
CPEB4
cytoplasmic polyadenylation element binding protein 4
chr3_-_167452262 0.24 ENST00000487947.2
PDCD10
programmed cell death 10
chr2_+_33359646 0.24 ENST00000390003.4
ENST00000418533.2
LTBP1
latent transforming growth factor beta binding protein 1
chr20_+_9049682 0.23 ENST00000334005.3
ENST00000378473.3
PLCB4
phospholipase C, beta 4
chr4_-_153274078 0.22 ENST00000263981.5
FBXW7
F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
chr11_-_46142505 0.22 ENST00000524497.1
ENST00000418153.2
PHF21A
PHD finger protein 21A
chr1_+_2066252 0.21 ENST00000466352.1
PRKCZ
protein kinase C, zeta
chr3_-_71114066 0.21 ENST00000485326.2
FOXP1
forkhead box P1
chr3_+_57875738 0.21 ENST00000417128.1
ENST00000438794.1
SLMAP
sarcolemma associated protein
chr16_-_69419473 0.20 ENST00000566750.1
TERF2
telomeric repeat binding factor 2
chr15_-_59500973 0.20 ENST00000560749.1
MYO1E
myosin IE
chr2_-_65593784 0.19 ENST00000443619.2
SPRED2
sprouty-related, EVH1 domain containing 2
chr2_+_33359473 0.18 ENST00000432635.1
LTBP1
latent transforming growth factor beta binding protein 1
chr2_+_162087577 0.18 ENST00000439442.1
TANK
TRAF family member-associated NFKB activator
chr7_-_87849340 0.18 ENST00000419179.1
ENST00000265729.2
SRI
sorcin
chr5_+_36608280 0.18 ENST00000513646.1
SLC1A3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr14_-_24711806 0.17 ENST00000540705.1
ENST00000538777.1
ENST00000558566.1
ENST00000559019.1
TINF2
TERF1 (TRF1)-interacting nuclear factor 2
chr19_+_11546093 0.17 ENST00000591462.1
PRKCSH
protein kinase C substrate 80K-H
chr8_-_116680833 0.17 ENST00000220888.5
TRPS1
trichorhinophalangeal syndrome I
chr18_-_53255379 0.17 ENST00000565908.2
TCF4
transcription factor 4
chr2_+_181845763 0.16 ENST00000602499.1
UBE2E3
ubiquitin-conjugating enzyme E2E 3
chr1_+_43855560 0.16 ENST00000562955.1
SZT2
seizure threshold 2 homolog (mouse)
chr1_-_161207986 0.16 ENST00000506209.1
ENST00000367980.2
NR1I3
nuclear receptor subfamily 1, group I, member 3
chr5_-_115872142 0.15 ENST00000510263.1
SEMA6A
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
chr12_-_46766577 0.15 ENST00000256689.5
SLC38A2
solute carrier family 38, member 2
chrX_+_95939638 0.14 ENST00000373061.3
ENST00000373054.4
ENST00000355827.4
DIAPH2
diaphanous-related formin 2
chr2_+_201980827 0.14 ENST00000309955.3
ENST00000443227.1
ENST00000341222.6
ENST00000355558.4
ENST00000340870.5
ENST00000341582.6
CFLAR
CASP8 and FADD-like apoptosis regulator
chr5_+_72509751 0.14 ENST00000515556.1
ENST00000513379.1
ENST00000427584.2
RP11-60A8.1
RP11-60A8.1
chr9_+_135457530 0.14 ENST00000263610.2
BARHL1
BarH-like homeobox 1
chr11_+_111473108 0.14 ENST00000304987.3
SIK2
salt-inducible kinase 2
chr1_-_161208013 0.13 ENST00000515452.1
ENST00000367983.4
NR1I3
nuclear receptor subfamily 1, group I, member 3
chr5_+_140027355 0.13 ENST00000417647.2
ENST00000507593.1
ENST00000508301.1
IK
IK cytokine, down-regulator of HLA II
chr3_+_186383741 0.13 ENST00000232003.4
HRG
histidine-rich glycoprotein
chr7_-_127032114 0.13 ENST00000436992.1
ZNF800
zinc finger protein 800
chr4_-_100242549 0.12 ENST00000305046.8
ENST00000394887.3
ADH1B
alcohol dehydrogenase 1B (class I), beta polypeptide
chr16_+_81070792 0.12 ENST00000564241.1
ENST00000565237.1
ATMIN
ATM interactor
chr4_-_186578674 0.12 ENST00000438278.1
SORBS2
sorbin and SH3 domain containing 2
chr3_-_47950745 0.12 ENST00000429422.1
MAP4
microtubule-associated protein 4
chr17_-_76713100 0.11 ENST00000585509.1
CYTH1
cytohesin 1
chr1_+_202317815 0.11 ENST00000608999.1
ENST00000336894.4
ENST00000480184.1
PPP1R12B
protein phosphatase 1, regulatory subunit 12B
chr3_+_19988566 0.11 ENST00000273047.4
RAB5A
RAB5A, member RAS oncogene family
chr5_-_159846399 0.10 ENST00000297151.4
SLU7
SLU7 splicing factor homolog (S. cerevisiae)
chr4_+_90033968 0.09 ENST00000317005.2
TIGD2
tigger transposable element derived 2
chr16_-_3350614 0.09 ENST00000268674.2
TIGD7
tigger transposable element derived 7
chr5_-_88179017 0.09 ENST00000514028.1
ENST00000514015.1
ENST00000503075.1
ENST00000437473.2
MEF2C
myocyte enhancer factor 2C
chr9_-_113761720 0.09 ENST00000541779.1
ENST00000374430.2
LPAR1
lysophosphatidic acid receptor 1
chr5_-_1882858 0.08 ENST00000511126.1
ENST00000231357.2
IRX4
iroquois homeobox 4
chr17_+_75369400 0.08 ENST00000590059.1
SEPT9
septin 9
chr8_-_120685608 0.08 ENST00000427067.2
ENPP2
ectonucleotide pyrophosphatase/phosphodiesterase 2
chr6_+_121756809 0.08 ENST00000282561.3
GJA1
gap junction protein, alpha 1, 43kDa
chr7_-_144533074 0.07 ENST00000360057.3
ENST00000378099.3
TPK1
thiamin pyrophosphokinase 1
chr3_-_193272874 0.07 ENST00000342695.4
ATP13A4
ATPase type 13A4
chr19_-_55453077 0.07 ENST00000328092.5
ENST00000590030.1
NLRP7
NLR family, pyrin domain containing 7
chr1_-_154178803 0.07 ENST00000368525.3
C1orf189
chromosome 1 open reading frame 189
chr4_-_2420335 0.06 ENST00000503000.1
ZFYVE28
zinc finger, FYVE domain containing 28
chr15_-_55657428 0.06 ENST00000568543.1
CCPG1
cell cycle progression 1
chr9_+_4662282 0.06 ENST00000381883.2
PPAPDC2
phosphatidic acid phosphatase type 2 domain containing 2
chr11_-_46142615 0.06 ENST00000529734.1
ENST00000323180.6
PHF21A
PHD finger protein 21A
chr12_-_22094336 0.06 ENST00000326684.4
ABCC9
ATP-binding cassette, sub-family C (CFTR/MRP), member 9
chr21_+_17791648 0.06 ENST00000602892.1
ENST00000418813.2
ENST00000435697.1
LINC00478
long intergenic non-protein coding RNA 478
chr4_+_177796841 0.06 ENST00000508790.1
RP11-765K14.1
RP11-765K14.1
chr11_-_111741994 0.06 ENST00000398006.2
ALG9
ALG9, alpha-1,2-mannosyltransferase
chr1_+_218519577 0.05 ENST00000366930.4
ENST00000366929.4
TGFB2
transforming growth factor, beta 2
chr2_-_26205550 0.05 ENST00000405914.1
KIF3C
kinesin family member 3C
chr18_+_7754957 0.05 ENST00000400053.4
PTPRM
protein tyrosine phosphatase, receptor type, M
chr5_-_88178964 0.05 ENST00000513252.1
ENST00000508569.1
ENST00000510942.1
ENST00000506554.1
MEF2C
myocyte enhancer factor 2C
chr6_-_31612808 0.05 ENST00000438149.1
BAG6
BCL2-associated athanogene 6
chr12_+_10365404 0.05 ENST00000266458.5
ENST00000421801.2
ENST00000544284.1
ENST00000545047.1
ENST00000543602.1
ENST00000545887.1
GABARAPL1
GABA(A) receptor-associated protein like 1
chr19_+_10765003 0.05 ENST00000407004.3
ENST00000589998.1
ENST00000589600.1
ILF3
interleukin enhancer binding factor 3, 90kDa
chr19_-_19302931 0.05 ENST00000444486.3
ENST00000514819.3
ENST00000585679.1
ENST00000162023.5
MEF2BNB-MEF2B
MEF2BNB
MEF2B
MEF2BNB-MEF2B readthrough
MEF2B neighbor
myocyte enhancer factor 2B
chr16_+_24741013 0.04 ENST00000315183.7
ENST00000395799.3
TNRC6A
trinucleotide repeat containing 6A
chr5_-_157161727 0.04 ENST00000599823.1
AC026407.1
Uncharacterized protein
chrX_-_33146477 0.04 ENST00000378677.2
DMD
dystrophin
chr15_+_38276910 0.04 ENST00000558081.2
RP11-1008C21.1
RP11-1008C21.1
chr12_+_111374375 0.04 ENST00000553177.1
ENST00000548368.1
ENST00000331096.2
ENST00000547607.1
RP1-46F2.2
RP1-46F2.2
chr9_+_116173000 0.03 ENST00000288462.4
C9orf43
chromosome 9 open reading frame 43
chr14_+_65878650 0.03 ENST00000555559.1
FUT8
fucosyltransferase 8 (alpha (1,6) fucosyltransferase)
chr9_+_75766763 0.02 ENST00000456643.1
ENST00000415424.1
ANXA1
annexin A1
chr7_-_22234381 0.02 ENST00000458533.1
RAPGEF5
Rap guanine nucleotide exchange factor (GEF) 5
chr7_-_22233442 0.02 ENST00000401957.2
RAPGEF5
Rap guanine nucleotide exchange factor (GEF) 5
chr1_-_155271213 0.02 ENST00000342741.4
PKLR
pyruvate kinase, liver and RBC
chr1_+_84609944 0.01 ENST00000370685.3
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr12_-_22094159 0.01 ENST00000538350.1
ABCC9
ATP-binding cassette, sub-family C (CFTR/MRP), member 9
chrX_-_65259914 0.01 ENST00000374737.4
ENST00000455586.2
VSIG4
V-set and immunoglobulin domain containing 4
chrX_+_9935392 0.01 ENST00000445307.2
AC002365.1
Homo sapiens uncharacterized LOC100288814 (LOC100288814), mRNA.
chr9_+_97562440 0.01 ENST00000395357.2
C9orf3
chromosome 9 open reading frame 3
chr1_-_27701307 0.01 ENST00000270879.4
ENST00000354982.2
FCN3
ficolin (collagen/fibrinogen domain containing) 3
chr7_+_35756400 0.00 ENST00000585952.1
AC018647.3
AC018647.3
chr13_+_49684445 0.00 ENST00000398316.3
FNDC3A
fibronectin type III domain containing 3A
chr1_-_248005254 0.00 ENST00000355784.2
OR11L1
olfactory receptor, family 11, subfamily L, member 1

Network of associatons between targets according to the STRING database.

First level regulatory network of FUBP1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 3.0 GO:0006542 glutamine biosynthetic process(GO:0006542)
0.4 2.2 GO:1905167 positive regulation of lysosomal protein catabolic process(GO:1905167)
0.4 1.5 GO:1903045 neural crest cell migration involved in sympathetic nervous system development(GO:1903045)
0.3 1.1 GO:0044314 protein K27-linked ubiquitination(GO:0044314)
0.3 1.0 GO:1904647 response to rotenone(GO:1904647)
0.2 0.7 GO:1900085 negative regulation of peptidyl-tyrosine autophosphorylation(GO:1900085) negative regulation of inward rectifier potassium channel activity(GO:1903609)
0.2 0.6 GO:1904235 regulation of substrate-dependent cell migration, cell attachment to substrate(GO:1904235) positive regulation of substrate-dependent cell migration, cell attachment to substrate(GO:1904237)
0.2 0.5 GO:0007388 anterior compartment pattern formation(GO:0007387) posterior compartment specification(GO:0007388)
0.2 1.4 GO:1903551 regulation of extracellular exosome assembly(GO:1903551)
0.2 2.5 GO:0008090 retrograde axonal transport(GO:0008090)
0.1 5.4 GO:0031581 hemidesmosome assembly(GO:0031581)
0.1 0.6 GO:1904383 response to sodium phosphate(GO:1904383)
0.1 0.4 GO:0032764 negative regulation of mast cell cytokine production(GO:0032764) negative regulation of isotype switching to IgE isotypes(GO:0048294)
0.1 0.6 GO:1904219 regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) positive regulation of serine C-palmitoyltransferase activity(GO:1904222)
0.1 0.5 GO:0071477 hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
0.1 0.6 GO:0072619 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.1 0.6 GO:0060671 epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
0.1 0.5 GO:1903588 negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903588)
0.1 0.3 GO:2000342 negative regulation of chemokine (C-X-C motif) ligand 2 production(GO:2000342)
0.1 0.9 GO:0034350 regulation of glial cell apoptotic process(GO:0034350) negative regulation of glial cell apoptotic process(GO:0034351)
0.1 0.3 GO:0002296 T-helper 1 cell lineage commitment(GO:0002296)
0.1 0.5 GO:1901668 regulation of superoxide dismutase activity(GO:1901668)
0.1 0.7 GO:0035583 sequestering of TGFbeta in extracellular matrix(GO:0035583)
0.1 0.5 GO:0010836 negative regulation of protein ADP-ribosylation(GO:0010836)
0.1 0.5 GO:1902952 positive regulation of dendritic spine maintenance(GO:1902952) regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903756) negative regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903758)
0.1 0.3 GO:0048388 endosomal lumen acidification(GO:0048388)
0.0 0.4 GO:0048625 regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334) myoblast fate commitment(GO:0048625) positive regulation of proteoglycan biosynthetic process(GO:1902730)
0.0 0.2 GO:1903517 regulation of telomere maintenance via recombination(GO:0032207) negative regulation of telomere maintenance via recombination(GO:0032208) regulation of single strand break repair(GO:1903516) negative regulation of single strand break repair(GO:1903517) negative regulation of beta-galactosidase activity(GO:1903770) telomere single strand break repair(GO:1903823) negative regulation of telomere single strand break repair(GO:1903824)
0.0 0.3 GO:0097368 establishment of Sertoli cell barrier(GO:0097368)
0.0 0.2 GO:2000639 regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
0.0 0.1 GO:2001027 negative regulation of endothelial cell chemotaxis(GO:2001027)
0.0 1.3 GO:0046339 diacylglycerol metabolic process(GO:0046339)
0.0 0.4 GO:0015820 leucine transport(GO:0015820)
0.0 0.3 GO:0046940 nucleoside monophosphate phosphorylation(GO:0046940)
0.0 0.3 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.0 0.2 GO:0035166 post-embryonic hemopoiesis(GO:0035166)
0.0 0.5 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.0 0.2 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.0 0.3 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.0 0.4 GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
0.0 0.2 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.0 0.2 GO:0097577 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.0 0.2 GO:1903367 positive regulation of fear response(GO:1903367) positive regulation of behavioral fear response(GO:2000987)
0.0 0.6 GO:0045898 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.0 0.1 GO:0003275 apoptotic process involved in outflow tract morphogenesis(GO:0003275) uterine wall breakdown(GO:0042704) positive regulation of catagen(GO:0051795) regulation of apoptotic process involved in outflow tract morphogenesis(GO:1902256)
0.0 0.1 GO:2000286 receptor internalization involved in canonical Wnt signaling pathway(GO:2000286)
0.0 0.2 GO:2001181 positive regulation of interleukin-10 secretion(GO:2001181)
0.0 0.1 GO:1904566 response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566)
0.0 0.1 GO:0051012 microtubule sliding(GO:0051012)
0.0 0.2 GO:0070779 gamma-aminobutyric acid biosynthetic process(GO:0009449) D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.0 0.3 GO:0060009 Sertoli cell development(GO:0060009)
0.0 0.4 GO:0071361 cellular response to ethanol(GO:0071361)
0.0 0.2 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.0 0.4 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.0 1.4 GO:0030166 proteoglycan biosynthetic process(GO:0030166)
0.0 0.3 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.0 0.2 GO:0032328 alanine transport(GO:0032328)
0.0 0.4 GO:0016246 RNA interference(GO:0016246)
0.0 0.1 GO:1903944 regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.0 0.4 GO:0035455 response to interferon-alpha(GO:0035455)
0.0 0.1 GO:2001106 regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.5 GO:0031673 H zone(GO:0031673)
0.2 5.4 GO:0030056 hemidesmosome(GO:0030056)
0.2 1.4 GO:0033565 ESCRT-0 complex(GO:0033565)
0.1 3.0 GO:0097386 glial cell projection(GO:0097386)
0.1 0.4 GO:0097232 lamellar body membrane(GO:0097232) alveolar lamellar body membrane(GO:0097233)
0.1 0.5 GO:0010370 perinucleolar chromocenter(GO:0010370)
0.1 0.5 GO:1990130 Iml1 complex(GO:1990130)
0.0 0.4 GO:0071664 beta-catenin-TCF7L2 complex(GO:0070369) catenin-TCF7L2 complex(GO:0071664)
0.0 0.6 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.7 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.0 0.2 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.0 0.5 GO:0033391 chromatoid body(GO:0033391)
0.0 0.7 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.0 0.2 GO:0044326 dendritic spine neck(GO:0044326)
0.0 1.1 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.0 0.2 GO:0070187 telosome(GO:0070187)
0.0 1.6 GO:0035580 specific granule lumen(GO:0035580)
0.0 0.4 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.0 1.0 GO:1904115 axon cytoplasm(GO:1904115)
0.0 2.2 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 0.2 GO:0045179 apical cortex(GO:0045179)
0.0 0.2 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.1 GO:0098559 cytoplasmic side of early endosome membrane(GO:0098559)
0.0 0.1 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 3.0 GO:0016211 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.7 2.2 GO:0016964 alpha-2 macroglobulin receptor activity(GO:0016964)
0.3 1.6 GO:0004382 guanosine-diphosphatase activity(GO:0004382)
0.2 0.7 GO:0070320 inward rectifier potassium channel inhibitor activity(GO:0070320)
0.1 0.4 GO:0005298 proline:sodium symporter activity(GO:0005298)
0.1 0.9 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.1 0.7 GO:0050436 microfibril binding(GO:0050436)
0.1 0.4 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.1 0.3 GO:0017130 poly(C) RNA binding(GO:0017130)
0.1 1.5 GO:0030215 semaphorin receptor binding(GO:0030215)
0.1 0.4 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.1 0.3 GO:0046899 nucleoside triphosphate adenylate kinase activity(GO:0046899)
0.1 2.5 GO:0051010 microtubule plus-end binding(GO:0051010)
0.1 0.3 GO:0001010 transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010)
0.1 0.3 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.0 0.5 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.0 0.4 GO:0042835 BRE binding(GO:0042835)
0.0 0.3 GO:0004882 androgen receptor activity(GO:0004882)
0.0 1.3 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.2 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.0 1.0 GO:0044213 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.0 0.5 GO:0022820 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.0 0.7 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 0.6 GO:0015194 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0 0.2 GO:0004771 sterol esterase activity(GO:0004771)
0.0 0.3 GO:0008310 single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
0.0 0.2 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.0 0.9 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 0.4 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 0.1 GO:0000386 second spliceosomal transesterification activity(GO:0000386)
0.0 0.6 GO:0004697 protein kinase C activity(GO:0004697)
0.0 0.1 GO:0008281 sulfonylurea receptor activity(GO:0008281)
0.0 0.2 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.0 1.7 GO:0050681 androgen receptor binding(GO:0050681)
0.0 0.2 GO:0097027 ubiquitin-protein transferase activator activity(GO:0097027)
0.0 0.1 GO:0047391 alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391)
0.0 0.4 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.1 GO:0000026 alpha-1,2-mannosyltransferase activity(GO:0000026)
0.0 0.2 GO:0003964 telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.0 0.1 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.0 1.0 GO:1990939 ATP-dependent microtubule motor activity(GO:1990939)
0.0 0.1 GO:0004024 alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
0.0 0.5 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.6 GO:0016504 peptidase activator activity(GO:0016504)
0.0 0.3 GO:0005523 tropomyosin binding(GO:0005523)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 5.2 NABA COLLAGENS Genes encoding collagen proteins
0.0 2.8 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 2.5 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.3 SIG IL4RECEPTOR IN B LYPHOCYTES Genes related to IL4 rceptor signaling in B lymphocytes
0.0 0.7 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.0 1.5 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 1.1 ST G ALPHA I PATHWAY G alpha i Pathway
0.0 0.9 PID ENDOTHELIN PATHWAY Endothelins
0.0 1.3 PID IL2 1PATHWAY IL2-mediated signaling events
0.0 0.4 PID RHOA PATHWAY RhoA signaling pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.0 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.1 5.4 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.1 1.5 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 2.5 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 1.4 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.4 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.5 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 0.6 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.8 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.6 REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.0 0.4 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.3 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 0.7 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends