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SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for GATA5

Z-value: 0.90

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Transcription factors associated with GATA5

Gene Symbol Gene ID Gene Info
ENSG00000130700.6 GATA binding protein 5

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
GATA5hg19_v2_chr20_-_61051026_61051057-0.883.6e-07Click!

Activity profile of GATA5 motif

Sorted Z-values of GATA5 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr1_+_79115503 2.93 ENST00000370747.4
ENST00000438486.1
ENST00000545124.1
interferon-induced protein 44
chr4_-_110723134 2.59 ENST00000510800.1
ENST00000512148.1
complement factor I
chr5_+_147443534 2.26 ENST00000398454.1
ENST00000359874.3
ENST00000508733.1
ENST00000256084.7
serine peptidase inhibitor, Kazal type 5
chr10_+_118187379 2.17 ENST00000369230.3
pancreatic lipase-related protein 3
chr4_-_110723335 2.12 ENST00000394634.2
complement factor I
chr3_+_118905564 2.03 ENST00000460625.1
uroplakin 1B
chr17_-_74639886 1.97 ENST00000156626.7
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1
chr4_-_110723194 1.96 ENST00000394635.3
complement factor I
chrX_-_73061339 1.74 ENST00000602863.1
X inactive specific transcript (non-protein coding)
chr21_+_39668478 1.72 ENST00000398927.1
potassium inwardly-rectifying channel, subfamily J, member 15
chr1_+_174844645 1.69 ENST00000486220.1
RAB GTPase activating protein 1-like
chr6_+_106988986 1.65 ENST00000457437.1
ENST00000535438.1
absent in melanoma 1
chr6_+_31916733 1.60 ENST00000483004.1
complement factor B
chrM_+_3299 1.48 ENST00000361390.2
mitochondrially encoded NADH dehydrogenase 1
chrM_+_10053 1.33 ENST00000361227.2
mitochondrially encoded NADH dehydrogenase 3
chr10_-_98031265 1.14 ENST00000224337.5
ENST00000371176.2
B-cell linker
chrM_+_10758 1.10 ENST00000361381.2
mitochondrially encoded NADH dehydrogenase 4
chr20_+_22034809 1.10 ENST00000449427.1
RP11-125P18.1
chr14_-_61748550 0.97 ENST00000555868.1
transmembrane protein 30B
chr13_-_46756351 0.94 ENST00000323076.2
lymphocyte cytosolic protein 1 (L-plastin)
chr1_+_24645807 0.94 ENST00000361548.4
grainyhead-like 3 (Drosophila)
chr1_+_24645865 0.92 ENST00000342072.4
grainyhead-like 3 (Drosophila)
chr4_-_47983519 0.84 ENST00000358519.4
ENST00000544810.1
ENST00000402813.3
cyclic nucleotide gated channel alpha 1
chr1_+_104159999 0.83 ENST00000414303.2
ENST00000423678.1
amylase, alpha 2A (pancreatic)
chr8_-_97247759 0.82 ENST00000518406.1
ENST00000523920.1
ENST00000287022.5
ubiquinol-cytochrome c reductase binding protein
chr5_-_39270725 0.77 ENST00000512138.1
ENST00000512982.1
ENST00000540520.1
FYN binding protein
chr1_-_27481401 0.76 ENST00000263980.3
solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
chrM_+_10464 0.76 ENST00000361335.1
mitochondrially encoded NADH dehydrogenase 4L
chr11_-_33891362 0.75 ENST00000395833.3
LIM domain only 2 (rhombotin-like 1)
chr14_+_61995722 0.75 ENST00000556347.1
RP11-47I22.4
chr4_-_83769996 0.70 ENST00000511338.1
SEC31 homolog A (S. cerevisiae)
chr11_-_61734599 0.68 ENST00000532601.1
ferritin, heavy polypeptide 1
chr2_+_182850551 0.68 ENST00000452904.1
ENST00000409137.3
ENST00000280295.3
protein phosphatase 1, regulatory (inhibitor) subunit 1C
chr4_-_83765613 0.67 ENST00000503937.1
SEC31 homolog A (S. cerevisiae)
chr2_+_102615416 0.67 ENST00000393414.2
interleukin 1 receptor, type II
chr1_+_24645915 0.65 ENST00000350501.5
grainyhead-like 3 (Drosophila)
chr3_+_177545563 0.64 ENST00000434309.1
RP11-91K9.1
chr19_-_19739321 0.64 ENST00000588461.1
lysophosphatidic acid receptor 2
chr3_-_183145873 0.63 ENST00000447025.2
ENST00000414362.2
ENST00000328913.3
MCF.2 cell line derived transforming sequence-like 2
chr1_+_150954493 0.63 ENST00000368947.4
annexin A9
chr5_+_145316120 0.62 ENST00000359120.4
SH3 domain containing ring finger 2
chr1_-_100643765 0.62 ENST00000370137.1
ENST00000370138.1
ENST00000342895.3
leucine rich repeat containing 39
chr17_-_74639730 0.60 ENST00000589992.1
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1
chr8_+_9046503 0.59 ENST00000512942.2
RP11-10A14.5
chr1_+_78245466 0.58 ENST00000477627.2
family with sequence similarity 73, member A
chrX_+_1733876 0.57 ENST00000381241.3
acetylserotonin O-methyltransferase
chr15_-_49912987 0.57 ENST00000560246.1
ENST00000558594.1
family with sequence similarity 227, member B
chr8_+_55466915 0.55 ENST00000522711.2
RP11-53M11.3
chr1_+_171454639 0.54 ENST00000392078.3
ENST00000426496.2
proline-rich coiled-coil 2C
chr1_+_171454659 0.53 ENST00000367742.3
ENST00000338920.4
proline-rich coiled-coil 2C
chr22_+_21213771 0.53 ENST00000439214.1
synaptosomal-associated protein, 29kDa
chr15_-_49912944 0.53 ENST00000559905.1
family with sequence similarity 227, member B
chr3_-_143567262 0.53 ENST00000474151.1
ENST00000316549.6
solute carrier family 9, subfamily A (NHE9, cation proton antiporter 9), member 9
chr2_+_102928009 0.53 ENST00000404917.2
ENST00000447231.1
interleukin 1 receptor-like 1
chr15_-_49913126 0.52 ENST00000561064.1
ENST00000299338.6
family with sequence similarity 227, member B
chr1_+_207277590 0.51 ENST00000367070.3
complement component 4 binding protein, alpha
chr3_+_101659682 0.51 ENST00000465215.1
RP11-221J22.1
chr7_+_18330035 0.49 ENST00000413509.2
histone deacetylase 9
chr18_-_21891460 0.49 ENST00000357041.4
oxysterol binding protein-like 1A
chr11_+_128563652 0.47 ENST00000527786.2
Fli-1 proto-oncogene, ETS transcription factor
chr4_+_57276661 0.47 ENST00000598320.1
Uncharacterized protein
chr8_+_93895865 0.47 ENST00000391681.1
AC117834.1
chr18_-_5419797 0.46 ENST00000542146.1
ENST00000427684.2
erythrocyte membrane protein band 4.1-like 3
chr10_+_90484301 0.45 ENST00000404190.1
lipase, family member K
chr4_+_155484155 0.45 ENST00000509493.1
fibrinogen beta chain
chr18_+_21032781 0.44 ENST00000339486.3
RIO kinase 3
chr6_-_137365402 0.44 ENST00000541547.1
interleukin 20 receptor, alpha
chr9_-_70490107 0.44 ENST00000377395.4
ENST00000429800.2
ENST00000430059.2
ENST00000377384.1
ENST00000382405.3
COBW domain containing 5
chr13_-_107214291 0.43 ENST00000375926.1
arginine and glutamate rich 1
chr13_+_102142296 0.42 ENST00000376162.3
integrin, beta-like 1 (with EGF-like repeat domains)
chr15_+_66874502 0.42 ENST00000558797.1
HCG2003567; Uncharacterized protein
chr8_-_42360015 0.42 ENST00000522707.1
solute carrier family 20 (phosphate transporter), member 2
chr4_-_137842536 0.41 ENST00000512039.1
RP11-138I17.1
chr10_+_75668916 0.40 ENST00000481390.1
plasminogen activator, urokinase
chr14_-_105420241 0.40 ENST00000557457.1
AHNAK nucleoprotein 2
chr7_+_143771275 0.38 ENST00000408898.2
olfactory receptor, family 2, subfamily A, member 25
chr16_+_82068873 0.36 ENST00000566213.1
hydroxysteroid (17-beta) dehydrogenase 2
chr5_+_140753444 0.36 ENST00000517434.1
protocadherin gamma subfamily A, 6
chr1_+_156123318 0.36 ENST00000368285.3
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
chr5_+_38445641 0.35 ENST00000397210.3
ENST00000506135.1
ENST00000508131.1
EGF-like, fibronectin type III and laminin G domains
chr3_+_44916098 0.34 ENST00000296125.4
transglutaminase 4
chr21_-_31852663 0.34 ENST00000390689.2
keratin associated protein 19-1
chr5_+_140602904 0.34 ENST00000515856.2
ENST00000239449.4
protocadherin beta 14
chrX_+_1734051 0.34 ENST00000381229.4
ENST00000381233.3
acetylserotonin O-methyltransferase
chr3_-_156878540 0.34 ENST00000461804.1
cyclin L1
chr10_+_115999004 0.33 ENST00000603594.1
von Willebrand factor A domain containing 2
chr10_-_46342675 0.32 ENST00000492347.1
ArfGAP with GTPase domain, ankyrin repeat and PH domain 4
chr2_+_62132781 0.32 ENST00000311832.5
copper metabolism (Murr1) domain containing 1
chr22_-_29107919 0.31 ENST00000434810.1
ENST00000456369.1
checkpoint kinase 2
chr2_+_102927962 0.31 ENST00000233954.1
ENST00000393393.3
ENST00000410040.1
interleukin 1 receptor-like 1
interleukin 18 receptor 1
chr11_+_114310164 0.31 ENST00000544196.1
ENST00000539754.1
ENST00000539275.1
RNA exonuclease 2
chr12_-_102455846 0.30 ENST00000545679.1
coiled-coil domain containing 53
chr12_-_30887948 0.30 ENST00000433722.2
caprin family member 2
chr8_-_121825088 0.29 ENST00000520717.1
syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1)
chr12_-_102455902 0.28 ENST00000240079.6
coiled-coil domain containing 53
chr18_+_48918368 0.28 ENST00000583982.1
ENST00000578152.1
ENST00000583609.1
ENST00000435144.1
ENST00000580841.1
RP11-267C16.1
chr3_-_178969403 0.28 ENST00000314235.5
ENST00000392685.2
potassium large conductance calcium-activated channel, subfamily M beta member 3
chr13_+_107029084 0.28 ENST00000444865.1
long intergenic non-protein coding RNA 460
chr10_+_15085895 0.27 ENST00000378228.3
oleoyl-ACP hydrolase
chr1_+_171939240 0.27 ENST00000523513.1
dynamin 3
chr10_+_15085936 0.27 ENST00000378217.3
oleoyl-ACP hydrolase
chr11_+_114310102 0.27 ENST00000265881.5
RNA exonuclease 2
chr17_+_41322483 0.27 ENST00000341165.6
ENST00000586650.1
ENST00000422280.1
neighbor of BRCA1 gene 1
chrX_+_100645812 0.26 ENST00000427805.2
ENST00000553110.3
ENST00000392994.3
ENST00000409338.1
ENST00000409170.3
ribosomal protein L36a
RPL36A-HNRNPH2 readthrough
chr13_+_107028897 0.25 ENST00000439790.1
ENST00000435024.1
long intergenic non-protein coding RNA 460
chr21_-_30047095 0.25 ENST00000452028.1
ENST00000433310.2
AF131217.1
chr21_+_25801041 0.25 ENST00000453784.2
ENST00000423581.1
AP000476.1
chr11_-_14379997 0.24 ENST00000526063.1
ENST00000532814.1
related RAS viral (r-ras) oncogene homolog 2
chr10_+_103911926 0.24 ENST00000605788.1
ENST00000405356.1
nucleolar and coiled-body phosphoprotein 1
chr13_-_45048386 0.24 ENST00000472477.1
TSC22 domain family, member 1
chr6_+_76599809 0.24 ENST00000430435.1
myosin VI
chr7_+_134331550 0.24 ENST00000344924.3
ENST00000418040.1
ENST00000393132.2
2,3-bisphosphoglycerate mutase
chr11_+_118754475 0.23 ENST00000292174.4
chemokine (C-X-C motif) receptor 5
chr10_-_5638048 0.23 ENST00000478294.1
RP13-463N16.6
chr20_-_44333658 0.23 ENST00000330523.5
ENST00000335769.2
WAP four-disulfide core domain 10B
chr15_+_100106126 0.23 ENST00000558812.1
ENST00000338042.6
myocyte enhancer factor 2A
chr1_-_203274418 0.22 ENST00000457348.1
long intergenic non-protein coding RNA 1136
chr4_+_155484103 0.22 ENST00000302068.4
fibrinogen beta chain
chr15_+_45028719 0.22 ENST00000560442.1
ENST00000558329.1
ENST00000561043.1
tripartite motif containing 69
chr14_-_45252031 0.22 ENST00000556405.1
RP11-398E10.1
chr12_-_45270077 0.22 ENST00000551601.1
ENST00000549027.1
ENST00000452445.2
NEL-like 2 (chicken)
chr4_+_72897521 0.22 ENST00000308744.6
ENST00000344413.5
neuropeptide FF receptor 2
chr12_+_10331605 0.21 ENST00000298530.3
transmembrane protein 52B
chr7_-_123197733 0.21 ENST00000470123.1
ENST00000471770.1
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5
chr12_-_45270151 0.21 ENST00000429094.2
NEL-like 2 (chicken)
chr9_+_91933407 0.21 ENST00000375807.3
ENST00000339901.4
SECIS binding protein 2
chr6_-_43027105 0.21 ENST00000230413.5
ENST00000487429.1
ENST00000489623.1
ENST00000468957.1
mitochondrial ribosomal protein L2
chr12_+_75874580 0.21 ENST00000456650.3
GLI pathogenesis-related 1
chr6_-_133055896 0.20 ENST00000367927.5
ENST00000425515.2
ENST00000207771.3
ENST00000392393.3
ENST00000450865.2
ENST00000392394.2
vanin 3
chr7_-_86688990 0.20 ENST00000450689.2
KIAA1324-like
chr3_+_184080387 0.20 ENST00000455712.1
polymerase (RNA) II (DNA directed) polypeptide H
chr10_+_53806501 0.20 ENST00000373975.2
protein kinase, cGMP-dependent, type I
chr16_+_31366455 0.19 ENST00000268296.4
integrin, alpha X (complement component 3 receptor 4 subunit)
chr8_-_101730061 0.19 ENST00000519100.1
poly(A) binding protein, cytoplasmic 1
chr15_+_100106244 0.19 ENST00000557942.1
myocyte enhancer factor 2A
chr11_+_18433840 0.19 ENST00000541669.1
ENST00000280704.4
lactate dehydrogenase C
chr2_-_109605663 0.19 ENST00000409271.1
ENST00000258443.2
ENST00000376651.1
ectodysplasin A receptor
chr4_-_48782259 0.19 ENST00000507711.1
ENST00000358350.4
ENST00000537810.1
ENST00000264319.7
FRY-like
chr6_-_33290580 0.19 ENST00000446511.1
ENST00000446403.1
ENST00000414083.2
ENST00000266000.6
ENST00000374542.5
death-domain associated protein
chr1_-_89357179 0.18 ENST00000448623.1
ENST00000418217.1
ENST00000370500.5
general transcription factor IIB
chr6_-_117150198 0.18 ENST00000310357.3
ENST00000368549.3
ENST00000530250.1
G protein-coupled receptor, family C, group 6, member A
chr1_+_207277632 0.18 ENST00000421786.1
complement component 4 binding protein, alpha
chr3_-_10334585 0.18 ENST00000430179.1
ENST00000449238.2
ENST00000437422.2
ENST00000287656.7
ENST00000457360.1
ENST00000439975.2
ENST00000446937.2
ghrelin/obestatin prepropeptide
chr6_-_135271219 0.17 ENST00000367847.2
ENST00000367845.2
aldehyde dehydrogenase 8 family, member A1
chr20_+_56964169 0.17 ENST00000475243.1
VAMP (vesicle-associated membrane protein)-associated protein B and C
chr12_-_45269769 0.17 ENST00000548826.1
NEL-like 2 (chicken)
chr3_+_14061155 0.17 ENST00000532924.1
tetra-peptide repeat homeobox-like
chrX_-_70326455 0.17 ENST00000374251.5
chromosome X open reading frame 65
chr2_+_166150541 0.17 ENST00000283256.6
sodium channel, voltage-gated, type II, alpha subunit
chr2_+_179149636 0.17 ENST00000409631.1
oxysterol binding protein-like 6
chr11_+_22694123 0.16 ENST00000534801.1
growth arrest-specific 2
chr12_-_45269430 0.16 ENST00000395487.2
NEL-like 2 (chicken)
chr1_-_248802559 0.16 ENST00000317450.3
olfactory receptor, family 2, subfamily T, member 35
chr19_+_9296279 0.16 ENST00000344248.2
olfactory receptor, family 7, subfamily D, member 2
chr16_+_31366536 0.16 ENST00000562522.1
integrin, alpha X (complement component 3 receptor 4 subunit)
chr12_-_54582655 0.16 ENST00000504338.1
ENST00000514685.1
ENST00000504797.1
ENST00000513838.1
ENST00000505128.1
ENST00000337581.3
ENST00000503306.1
ENST00000243112.5
ENST00000514196.1
ENST00000506169.1
ENST00000507904.1
ENST00000508394.2
single-strand-selective monofunctional uracil-DNA glycosylase 1
chr7_+_142448053 0.16 ENST00000422143.2
T cell receptor beta variable 29-1
chr6_-_135271260 0.15 ENST00000265605.2
aldehyde dehydrogenase 8 family, member A1
chrX_-_117119243 0.15 ENST00000539496.1
ENST00000469946.1
kelch-like family member 13
chr4_-_65275162 0.15 ENST00000381210.3
ENST00000507440.1
trans-2,3-enoyl-CoA reductase-like
chr19_-_9226439 0.15 ENST00000293614.1
ENST00000541538.1
olfactory receptor, family 7, subfamily G, member 1
chr11_+_57308979 0.14 ENST00000457912.1
smoothelin-like 1
chr18_-_3874752 0.14 ENST00000534970.1
discs, large (Drosophila) homolog-associated protein 1
chrX_-_72097698 0.14 ENST00000373530.1
DMRT-like family C1
chr3_-_178984759 0.14 ENST00000349697.2
ENST00000497599.1
potassium large conductance calcium-activated channel, subfamily M beta member 3
chr13_-_99910620 0.14 ENST00000416594.1
G protein-coupled receptor 18
chr1_-_150669500 0.13 ENST00000271732.3
golgi phosphoprotein 3-like
chr17_-_74547256 0.13 ENST00000589145.1
cytoglobin
chr19_-_9213982 0.13 ENST00000305456.2
olfactory receptor, family 7, subfamily G, member 2
chr8_+_28196157 0.13 ENST00000522209.1
prepronociceptin
chr19_-_14889349 0.13 ENST00000315576.3
ENST00000392967.2
ENST00000346057.1
ENST00000353876.1
ENST00000353005.1
egf-like module containing, mucin-like, hormone receptor-like 2
chr1_-_158656488 0.13 ENST00000368147.4
spectrin, alpha, erythrocytic 1 (elliptocytosis 2)
chr6_+_33043703 0.13 ENST00000418931.2
ENST00000535465.1
major histocompatibility complex, class II, DP beta 1
chr20_+_32254286 0.13 ENST00000330271.4
actin-like 10
chr19_-_57967854 0.13 ENST00000321039.3
vomeronasal 1 receptor 1
chr3_+_46283944 0.12 ENST00000452454.1
ENST00000457243.1
chemokine (C-C motif) receptor 3
chr20_+_58571419 0.12 ENST00000244049.3
ENST00000350849.6
ENST00000456106.1
cadherin 26
chr3_+_46283863 0.12 ENST00000545097.1
ENST00000541018.1
chemokine (C-C motif) receptor 3
chr1_+_149239529 0.12 ENST00000457216.2
RP11-403I13.4
chr15_+_100106155 0.12 ENST00000557785.1
ENST00000558049.1
ENST00000449277.2
myocyte enhancer factor 2A
chr12_+_92817735 0.12 ENST00000378485.1
chronic lymphocytic leukemia up-regulated 1
chr14_+_23025534 0.12 ENST00000557595.1
Uncharacterized protein
chr13_-_99910673 0.12 ENST00000397473.2
ENST00000397470.2
G protein-coupled receptor 18
chr6_-_32557610 0.12 ENST00000360004.5
major histocompatibility complex, class II, DR beta 1
chr3_+_46283916 0.11 ENST00000395940.2
chemokine (C-C motif) receptor 3
chr1_+_248616077 0.11 ENST00000342927.3
olfactory receptor, family 2, subfamily T, member 2
chr11_+_101785727 0.11 ENST00000263468.8
KIAA1377
chr20_-_1448358 0.10 ENST00000381658.4
NSFL1 (p97) cofactor (p47)
chr5_+_140593509 0.10 ENST00000341948.4
protocadherin beta 13
chr4_+_71570430 0.10 ENST00000417478.2
RUN and FYVE domain containing 3
chrX_-_154060946 0.10 ENST00000369529.1
small integral membrane protein 9
chr10_-_49482907 0.09 ENST00000374201.3
ENST00000407470.4
FERM and PDZ domain containing 2
chr17_+_53344945 0.09 ENST00000575345.1
hepatic leukemia factor
chr13_+_32313658 0.09 ENST00000380314.1
ENST00000298386.2
relaxin/insulin-like family peptide receptor 2
chr10_-_45803286 0.09 ENST00000536058.1
olfactory receptor, family 13, subfamily A, member 1
chr3_-_49837254 0.09 ENST00000412678.2
ENST00000343366.4
ENST00000487256.1
cadherin-related family member 4
chr6_+_42018614 0.09 ENST00000465926.1
ENST00000482432.1
TAF8 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 43kDa
chr17_-_45908875 0.09 ENST00000351111.2
ENST00000414011.1
mitochondrial ribosomal protein L10
chr21_-_19858196 0.09 ENST00000422787.1
transmembrane protease, serine 15
chr16_+_31539183 0.09 ENST00000302312.4
alpha hemoglobin stabilizing protein

Network of associatons between targets according to the STRING database.

First level regulatory network of GATA5

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.3 GO:0002784 regulation of antimicrobial peptide production(GO:0002784) regulation of antibacterial peptide production(GO:0002786)
0.3 0.9 GO:0030187 melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187)
0.2 0.7 GO:0086092 regulation of the force of heart contraction by cardiac conduction(GO:0086092)
0.2 0.7 GO:0050712 negative regulation of interleukin-1 alpha production(GO:0032690) negative regulation of interleukin-1 alpha secretion(GO:0050712)
0.1 0.8 GO:0044245 polysaccharide digestion(GO:0044245)
0.1 2.6 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.1 0.8 GO:0038172 interleukin-33-mediated signaling pathway(GO:0038172)
0.1 0.5 GO:0016240 autophagosome docking(GO:0016240)
0.1 0.3 GO:1903925 signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926)
0.1 2.5 GO:0090179 planar cell polarity pathway involved in neural tube closure(GO:0090179)
0.1 0.4 GO:2000097 regulation of smooth muscle cell-matrix adhesion(GO:2000097)
0.1 0.3 GO:0098884 postsynaptic neurotransmitter receptor internalization(GO:0098884)
0.1 0.4 GO:0039534 negative regulation of MDA-5 signaling pathway(GO:0039534)
0.1 0.7 GO:0097577 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.1 0.8 GO:0097033 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.1 8.9 GO:0030449 regulation of complement activation(GO:0030449)
0.1 0.3 GO:0002305 gamma-delta intraepithelial T cell differentiation(GO:0002304) CD8-positive, gamma-delta intraepithelial T cell differentiation(GO:0002305)
0.1 0.2 GO:0019516 lactate oxidation(GO:0019516)
0.1 0.2 GO:0072737 response to diamide(GO:0072737) cellular response to diamide(GO:0072738)
0.1 1.4 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.1 4.9 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.1 0.2 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
0.1 0.2 GO:1990768 positive regulation of growth rate(GO:0040010) regulation of gastric mucosal blood circulation(GO:1904344) positive regulation of gastric mucosal blood circulation(GO:1904346) gastric mucosal blood circulation(GO:1990768)
0.1 0.5 GO:0055005 ventricular cardiac myofibril assembly(GO:0055005) ERK5 cascade(GO:0070375)
0.1 0.5 GO:0002175 protein localization to paranode region of axon(GO:0002175)
0.0 0.8 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.0 0.7 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.0 0.8 GO:0070863 positive regulation of protein exit from endoplasmic reticulum(GO:0070863)
0.0 0.9 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.0 0.4 GO:2000622 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.0 0.3 GO:0042905 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.0 0.5 GO:1990118 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 1.7 GO:0010107 potassium ion import(GO:0010107)
0.0 0.3 GO:0007161 calcium-independent cell-matrix adhesion(GO:0007161)
0.0 0.4 GO:0001778 plasma membrane repair(GO:0001778)
0.0 0.4 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.0 0.8 GO:0042789 mRNA transcription from RNA polymerase II promoter(GO:0042789)
0.0 0.5 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.0 0.2 GO:1904798 positive regulation of core promoter binding(GO:1904798)
0.0 0.8 GO:0022400 regulation of rhodopsin mediated signaling pathway(GO:0022400)
0.0 0.2 GO:0007000 nucleolus organization(GO:0007000)
0.0 0.4 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.0 0.1 GO:0019236 response to pheromone(GO:0019236)
0.0 0.6 GO:0007202 activation of phospholipase C activity(GO:0007202)
0.0 0.8 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 0.3 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0 0.5 GO:0035855 megakaryocyte development(GO:0035855)
0.0 0.7 GO:1900087 positive regulation of G1/S transition of mitotic cell cycle(GO:1900087)
0.0 0.1 GO:0043376 regulation of CD8-positive, alpha-beta T cell differentiation(GO:0043376)
0.0 0.2 GO:0006987 activation of signaling protein activity involved in unfolded protein response(GO:0006987)
0.0 0.2 GO:0060087 relaxation of vascular smooth muscle(GO:0060087)
0.0 1.7 GO:0031338 regulation of vesicle fusion(GO:0031338)
0.0 0.6 GO:0006633 fatty acid biosynthetic process(GO:0006633)
0.0 0.2 GO:0015939 pantothenate metabolic process(GO:0015939)
0.0 0.2 GO:0060662 tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
0.0 0.7 GO:0006699 bile acid biosynthetic process(GO:0006699)
0.0 0.2 GO:0005513 detection of calcium ion(GO:0005513)
0.0 0.2 GO:0008627 intrinsic apoptotic signaling pathway in response to osmotic stress(GO:0008627)
0.0 0.1 GO:0048194 Golgi vesicle budding(GO:0048194)
0.0 0.2 GO:0015671 oxygen transport(GO:0015671)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.3 GO:0097209 epidermal lamellar body(GO:0097209)
0.2 0.7 GO:0070288 intracellular ferritin complex(GO:0008043) ferritin complex(GO:0070288)
0.1 0.3 GO:0098844 postsynaptic endocytic zone membrane(GO:0098844)
0.1 0.5 GO:0020018 ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018)
0.1 4.9 GO:0005747 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.1 0.8 GO:0045275 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.1 1.4 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.7 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.4 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 0.8 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 0.9 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.2 GO:1990730 VCP-NSFL1C complex(GO:1990730)
0.0 0.6 GO:0033270 paranode region of axon(GO:0033270)
0.0 0.7 GO:0090533 cation-transporting ATPase complex(GO:0090533)
0.0 0.1 GO:0032437 cuticular plate(GO:0032437)
0.0 0.2 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.0 0.3 GO:0043235 receptor complex(GO:0043235)
0.0 0.2 GO:0016461 unconventional myosin complex(GO:0016461)
0.0 0.3 GO:0005614 interstitial matrix(GO:0005614)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0002113 interleukin-33 binding(GO:0002113)
0.3 2.6 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.3 0.8 GO:0086040 sodium:proton antiporter activity involved in regulation of cardiac muscle cell membrane potential(GO:0086040)
0.2 0.8 GO:0004556 alpha-amylase activity(GO:0004556)
0.1 0.7 GO:0004910 interleukin-1, Type II, blocking receptor activity(GO:0004910)
0.1 0.6 GO:0016296 oleoyl-[acyl-carrier-protein] hydrolase activity(GO:0004320) myristoyl-[acyl-carrier-protein] hydrolase activity(GO:0016295) palmitoyl-[acyl-carrier-protein] hydrolase activity(GO:0016296) acyl-[acyl-carrier-protein] hydrolase activity(GO:0016297)
0.1 0.8 GO:0016681 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.1 0.9 GO:0008172 S-methyltransferase activity(GO:0008172)
0.1 0.3 GO:0031798 type 1 metabotropic glutamate receptor binding(GO:0031798)
0.1 2.6 GO:0004806 triglyceride lipase activity(GO:0004806)
0.1 0.2 GO:0060001 minus-end directed microfilament motor activity(GO:0060001)
0.1 4.9 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.1 1.7 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.1 0.4 GO:0042015 interleukin-20 binding(GO:0042015)
0.1 6.8 GO:0005044 scavenger receptor activity(GO:0005044)
0.1 0.2 GO:0004619 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.1 0.2 GO:0016608 growth hormone-releasing hormone activity(GO:0016608) ghrelin receptor binding(GO:0031768)
0.1 0.2 GO:0033149 FFAT motif binding(GO:0033149)
0.1 0.6 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.1 0.7 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.1 0.8 GO:0043855 intracellular cyclic nucleotide activated cation channel activity(GO:0005221) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.0 0.4 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.0 0.7 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0 0.5 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.0 1.6 GO:0001848 complement binding(GO:0001848)
0.0 0.1 GO:0016503 pheromone receptor activity(GO:0016503)
0.0 1.2 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0 0.2 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.0 0.2 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.0 0.1 GO:0047888 fatty acid peroxidase activity(GO:0047888)
0.0 0.1 GO:0001515 opioid peptide activity(GO:0001515)
0.0 0.4 GO:0089720 caspase binding(GO:0089720)
0.0 0.2 GO:0000702 oxidized base lesion DNA N-glycosylase activity(GO:0000702)
0.0 0.4 GO:0019957 C-C chemokine binding(GO:0019957)
0.0 0.2 GO:0035368 selenocysteine insertion sequence binding(GO:0035368)
0.0 0.3 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.4 GO:0004303 estradiol 17-beta-dehydrogenase activity(GO:0004303)
0.0 0.0 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.7 GO:0015464 acetylcholine receptor activity(GO:0015464)
0.0 0.2 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.0 0.1 GO:1902271 D3 vitamins binding(GO:1902271)
0.0 0.1 GO:0005499 vitamin D binding(GO:0005499)
0.0 0.2 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.0 0.2 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.0 0.1 GO:0030492 hemoglobin binding(GO:0030492)
0.0 0.6 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.5 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0 2.5 GO:0031490 chromatin DNA binding(GO:0031490)
0.0 2.1 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.7 GO:0015248 sterol transporter activity(GO:0015248)
0.0 1.3 GO:0098811 transcriptional activator activity, RNA polymerase II transcription factor binding(GO:0001190) transcriptional repressor activity, RNA polymerase II activating transcription factor binding(GO:0098811)
0.0 1.2 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 0.2 GO:0031628 opioid receptor binding(GO:0031628)
0.0 0.6 GO:0000175 3'-5'-exoribonuclease activity(GO:0000175)
0.0 0.5 GO:0005484 SNAP receptor activity(GO:0005484)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.6 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 1.7 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 1.1 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0 0.8 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.0 1.1 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 1.3 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 0.7 PID CD40 PATHWAY CD40/CD40L signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 9.0 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.1 0.8 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.0 0.7 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 0.8 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 1.3 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 1.7 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 1.1 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.0 0.9 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.0 0.8 REACTOME IRON UPTAKE AND TRANSPORT Genes involved in Iron uptake and transport
0.0 1.0 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 0.4 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.5 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets