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SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for GATA6

Z-value: 0.63

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Transcription factors associated with GATA6

Gene Symbol Gene ID Gene Info
GATA6
ENSG00000141448.4 GATA binding protein 6

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
GATA6hg19_v2_chr18_+_19750894_19750980-0.561.1e-02Click!

Activity profile of GATA6 motif

Sorted Z-values of GATA6 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr14_+_105952648 2.70 ENST00000330233.7
CRIP1
cysteine-rich protein 1 (intestinal)
chr6_+_12290586 2.12 ENST00000379375.5
EDN1
endothelin 1
chr7_-_107880508 2.05 ENST00000425651.2
NRCAM
neuronal cell adhesion molecule
chr9_+_118950325 1.79 ENST00000534838.1
PAPPA
pregnancy-associated plasma protein A, pappalysin 1
chr20_+_43029911 1.72 ENST00000443598.2
ENST00000316099.4
ENST00000415691.2
HNF4A
hepatocyte nuclear factor 4, alpha
chr14_+_100204027 1.58 ENST00000554479.1
ENST00000555145.1
EML1
echinoderm microtubule associated protein like 1
chr11_+_118958689 1.43 ENST00000535253.1
ENST00000392841.1
HMBS
hydroxymethylbilane synthase
chr14_-_23285069 1.34 ENST00000554758.1
ENST00000397528.4
SLC7A7
solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
chr7_-_100239132 1.19 ENST00000223051.3
ENST00000431692.1
TFR2
transferrin receptor 2
chr14_-_23285011 1.14 ENST00000397532.3
SLC7A7
solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
chr8_-_95449155 1.11 ENST00000481490.2
FSBP
fibrinogen silencer binding protein
chr10_-_99531709 1.09 ENST00000266066.3
SFRP5
secreted frizzled-related protein 5
chrX_-_10851762 1.04 ENST00000380785.1
ENST00000380787.1
MID1
midline 1 (Opitz/BBB syndrome)
chr14_-_23284703 0.87 ENST00000555911.1
SLC7A7
solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
chr17_+_4675175 0.85 ENST00000270560.3
TM4SF5
transmembrane 4 L six family member 5
chr11_-_66206260 0.85 ENST00000329819.4
ENST00000310999.7
ENST00000430466.2
MRPL11
mitochondrial ribosomal protein L11
chr18_-_2982869 0.84 ENST00000584915.1
LPIN2
lipin 2
chr17_+_38673270 0.82 ENST00000578280.1
RP5-1028K7.2
RP5-1028K7.2
chr19_-_11494975 0.78 ENST00000222139.6
ENST00000592375.2
EPOR
erythropoietin receptor
chr11_-_10920838 0.78 ENST00000503469.2
CTD-2003C8.2
CTD-2003C8.2
chr5_+_135496675 0.74 ENST00000507637.1
SMAD5
SMAD family member 5
chr20_-_54967187 0.72 ENST00000422322.1
ENST00000371356.2
ENST00000451915.1
ENST00000347343.2
ENST00000395911.1
ENST00000395907.1
ENST00000441357.1
ENST00000456249.1
ENST00000420474.1
ENST00000395909.4
ENST00000395914.1
ENST00000312783.6
ENST00000395915.3
ENST00000395913.3
AURKA
aurora kinase A
chr16_+_616995 0.64 ENST00000293874.2
ENST00000409527.2
ENST00000424439.2
ENST00000540585.1
PIGQ
NHLRC4
phosphatidylinositol glycan anchor biosynthesis, class Q
NHL repeat containing 4
chr6_-_86099898 0.60 ENST00000455071.1
RP11-30P6.6
RP11-30P6.6
chr22_-_20231207 0.60 ENST00000425986.1
RTN4R
reticulon 4 receptor
chr4_-_103266219 0.59 ENST00000394833.2
SLC39A8
solute carrier family 39 (zinc transporter), member 8
chr3_+_69812877 0.58 ENST00000457080.1
ENST00000328528.6
MITF
microphthalmia-associated transcription factor
chr19_+_36132631 0.55 ENST00000379026.2
ENST00000379023.4
ENST00000402764.2
ENST00000479824.1
ETV2
ets variant 2
chr7_+_155090271 0.53 ENST00000476756.1
INSIG1
insulin induced gene 1
chr2_+_109237717 0.52 ENST00000409441.1
LIMS1
LIM and senescent cell antigen-like domains 1
chr17_+_19314505 0.50 ENST00000461366.1
RNF112
ring finger protein 112
chr11_-_10920714 0.50 ENST00000533941.1
CTD-2003C8.2
CTD-2003C8.2
chr1_-_24469602 0.50 ENST00000270800.1
IL22RA1
interleukin 22 receptor, alpha 1
chr1_+_161136180 0.49 ENST00000352210.5
ENST00000367999.4
ENST00000544598.1
ENST00000535223.1
ENST00000432542.2
PPOX
protoporphyrinogen oxidase
chr1_-_205912577 0.49 ENST00000367135.3
ENST00000367134.2
SLC26A9
solute carrier family 26 (anion exchanger), member 9
chr2_+_3642545 0.46 ENST00000382062.2
ENST00000236693.7
ENST00000349077.4
COLEC11
collectin sub-family member 11
chr17_+_43224684 0.44 ENST00000332499.2
HEXIM1
hexamethylene bis-acetamide inducible 1
chr17_+_56833184 0.43 ENST00000308249.2
PPM1E
protein phosphatase, Mg2+/Mn2+ dependent, 1E
chr4_-_103266355 0.42 ENST00000424970.2
SLC39A8
solute carrier family 39 (zinc transporter), member 8
chr10_-_127505167 0.42 ENST00000368786.1
UROS
uroporphyrinogen III synthase
chr5_+_159848807 0.41 ENST00000352433.5
PTTG1
pituitary tumor-transforming 1
chr2_-_219850277 0.40 ENST00000295727.1
FEV
FEV (ETS oncogene family)
chr8_+_21823726 0.40 ENST00000433566.4
XPO7
exportin 7
chr18_-_28742813 0.38 ENST00000257197.3
ENST00000257198.5
DSC1
desmocollin 1
chr12_+_122880045 0.34 ENST00000539034.1
ENST00000535976.1
RP11-450K4.1
RP11-450K4.1
chr2_-_202298268 0.34 ENST00000440597.1
TRAK2
trafficking protein, kinesin binding 2
chr7_-_142659388 0.33 ENST00000476829.1
ENST00000467543.1
KEL
Kell blood group, metallo-endopeptidase
chr11_-_47374246 0.31 ENST00000545968.1
ENST00000399249.2
ENST00000256993.4
MYBPC3
myosin binding protein C, cardiac
chr14_+_53173890 0.30 ENST00000445930.2
PSMC6
proteasome (prosome, macropain) 26S subunit, ATPase, 6
chr17_+_4835580 0.29 ENST00000329125.5
GP1BA
glycoprotein Ib (platelet), alpha polypeptide
chr19_-_39303576 0.29 ENST00000594209.1
LGALS4
lectin, galactoside-binding, soluble, 4
chr14_-_23284675 0.26 ENST00000555959.1
SLC7A7
solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
chr14_-_38036271 0.25 ENST00000556024.1
RP11-356O9.2
RP11-356O9.2
chr17_+_19314432 0.24 ENST00000575165.2
RNF112
ring finger protein 112
chr15_+_49715293 0.24 ENST00000267843.4
ENST00000560270.1
FGF7
fibroblast growth factor 7
chr6_-_46048116 0.24 ENST00000185206.6
CLIC5
chloride intracellular channel 5
chr12_-_54689532 0.23 ENST00000540264.2
ENST00000312156.4
NFE2
nuclear factor, erythroid 2
chr4_+_15376165 0.23 ENST00000382383.3
ENST00000429690.1
C1QTNF7
C1q and tumor necrosis factor related protein 7
chr16_+_4475806 0.23 ENST00000262375.6
ENST00000355296.4
ENST00000431375.2
ENST00000574895.1
DNAJA3
DnaJ (Hsp40) homolog, subfamily A, member 3
chr9_-_114937676 0.22 ENST00000374270.3
SUSD1
sushi domain containing 1
chr10_-_21186144 0.22 ENST00000377119.1
NEBL
nebulette
chr17_+_72920698 0.22 ENST00000580223.1
OTOP2
otopetrin 2
chr13_+_24144509 0.22 ENST00000248484.4
TNFRSF19
tumor necrosis factor receptor superfamily, member 19
chr14_+_50999744 0.21 ENST00000441560.2
ATL1
atlastin GTPase 1
chr14_-_21945057 0.21 ENST00000397762.1
RAB2B
RAB2B, member RAS oncogene family
chr17_-_62084241 0.21 ENST00000449662.2
ICAM2
intercellular adhesion molecule 2
chr17_-_38938786 0.21 ENST00000301656.3
KRT27
keratin 27
chr2_-_40739501 0.20 ENST00000403092.1
ENST00000402441.1
ENST00000448531.1
SLC8A1
solute carrier family 8 (sodium/calcium exchanger), member 1
chr16_+_202686 0.20 ENST00000252951.2
HBZ
hemoglobin, zeta
chr20_-_60294804 0.20 ENST00000317652.1
RP11-429E11.3
Uncharacterized protein
chr1_+_66999799 0.20 ENST00000371035.3
ENST00000371036.3
ENST00000371037.4
SGIP1
SH3-domain GRB2-like (endophilin) interacting protein 1
chr15_-_38852251 0.19 ENST00000558432.1
RASGRP1
RAS guanyl releasing protein 1 (calcium and DAG-regulated)
chr1_-_167487808 0.17 ENST00000392122.3
CD247
CD247 molecule
chr1_-_167487758 0.17 ENST00000362089.5
CD247
CD247 molecule
chr13_+_24144796 0.16 ENST00000403372.2
TNFRSF19
tumor necrosis factor receptor superfamily, member 19
chr18_+_43304092 0.16 ENST00000321925.4
ENST00000587601.1
SLC14A1
solute carrier family 14 (urea transporter), member 1 (Kidd blood group)
chr2_-_44065889 0.16 ENST00000543989.1
ENST00000405322.1
ABCG5
ATP-binding cassette, sub-family G (WHITE), member 5
chr5_+_131892603 0.15 ENST00000378823.3
ENST00000265335.6
RAD50
RAD50 homolog (S. cerevisiae)
chr17_+_72920370 0.15 ENST00000331427.4
OTOP2
otopetrin 2
chr8_-_93107443 0.15 ENST00000360348.2
ENST00000520428.1
ENST00000518992.1
ENST00000520556.1
ENST00000518317.1
ENST00000521319.1
ENST00000521375.1
ENST00000518449.1
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr6_-_30128657 0.14 ENST00000449742.2
ENST00000376704.3
TRIM10
tripartite motif containing 10
chr4_+_166794383 0.14 ENST00000061240.2
ENST00000507499.1
TLL1
tolloid-like 1
chr1_-_42630389 0.14 ENST00000357001.2
GUCA2A
guanylate cyclase activator 2A (guanylin)
chr2_+_220436917 0.14 ENST00000243786.2
INHA
inhibin, alpha
chr1_+_171217677 0.14 ENST00000402921.2
FMO1
flavin containing monooxygenase 1
chr5_-_135290651 0.13 ENST00000522943.1
ENST00000514447.2
LECT2
leukocyte cell-derived chemotaxin 2
chr22_+_35462129 0.13 ENST00000404699.2
ENST00000308700.6
ISX
intestine-specific homeobox
chr7_+_142749417 0.13 ENST00000418316.1
OR6V1
olfactory receptor, family 6, subfamily V, member 1
chr11_+_10326918 0.12 ENST00000528544.1
ADM
adrenomedullin
chr15_+_81391740 0.11 ENST00000561216.1
C15orf26
chromosome 15 open reading frame 26
chr16_+_71560023 0.11 ENST00000572450.1
CHST4
carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 4
chr9_-_114937543 0.11 ENST00000374264.2
ENST00000374263.3
SUSD1
sushi domain containing 1
chr3_+_88188254 0.10 ENST00000309495.5
ZNF654
zinc finger protein 654
chr19_-_55549624 0.10 ENST00000417454.1
ENST00000310373.3
ENST00000333884.2
GP6
glycoprotein VI (platelet)
chr1_+_171217622 0.09 ENST00000433267.1
ENST00000367750.3
FMO1
flavin containing monooxygenase 1
chr5_+_131892815 0.08 ENST00000453394.1
RAD50
RAD50 homolog (S. cerevisiae)
chr16_+_333152 0.08 ENST00000219406.6
ENST00000404312.1
ENST00000456379.1
PDIA2
protein disulfide isomerase family A, member 2
chr9_-_117692697 0.08 ENST00000223795.2
TNFSF8
tumor necrosis factor (ligand) superfamily, member 8
chr11_+_10326612 0.07 ENST00000534464.1
ENST00000530439.1
ENST00000524948.1
ENST00000528655.1
ENST00000526492.1
ENST00000525063.1
ADM
adrenomedullin
chr8_-_93107696 0.07 ENST00000436581.2
ENST00000520583.1
ENST00000519061.1
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr1_+_206317591 0.07 ENST00000432969.2
CTSE
cathepsin E
chr1_-_158656488 0.07 ENST00000368147.4
SPTA1
spectrin, alpha, erythrocytic 1 (elliptocytosis 2)
chr10_+_118305435 0.07 ENST00000369221.2
PNLIP
pancreatic lipase
chr7_+_150690857 0.07 ENST00000484524.1
ENST00000467517.1
NOS3
nitric oxide synthase 3 (endothelial cell)
chr20_+_43935474 0.06 ENST00000372743.1
ENST00000372741.3
ENST00000343694.3
RBPJL
recombination signal binding protein for immunoglobulin kappa J region-like
chr16_+_71560154 0.06 ENST00000539698.3
CHST4
carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 4
chr3_-_122694215 0.06 ENST00000449546.1
SEMA5B
sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5B
chr3_+_69812701 0.06 ENST00000472437.1
MITF
microphthalmia-associated transcription factor
chr16_+_67022476 0.06 ENST00000540947.2
CES4A
carboxylesterase 4A
chr12_-_6233828 0.04 ENST00000572068.1
ENST00000261405.5
VWF
von Willebrand factor
chr2_+_173792893 0.04 ENST00000535187.1
RAPGEF4
Rap guanine nucleotide exchange factor (GEF) 4
chr18_+_43304137 0.04 ENST00000502059.2
ENST00000586951.1
ENST00000589322.2
ENST00000415427.3
ENST00000535474.1
ENST00000402943.2
SLC14A1
solute carrier family 14 (urea transporter), member 1 (Kidd blood group)
chr5_+_157602404 0.04 ENST00000522975.1
CTC-436K13.1
CTC-436K13.1
chr9_-_114937465 0.04 ENST00000355396.3
SUSD1
sushi domain containing 1
chr1_-_120354079 0.04 ENST00000354219.1
ENST00000369401.4
ENST00000256585.5
REG4
regenerating islet-derived family, member 4
chr12_-_120765565 0.04 ENST00000423423.3
ENST00000308366.4
PLA2G1B
phospholipase A2, group IB (pancreas)
chr3_+_137717571 0.03 ENST00000343735.4
CLDN18
claudin 18
chr11_-_116708302 0.01 ENST00000375320.1
ENST00000359492.2
ENST00000375329.2
ENST00000375323.1
APOA1
apolipoprotein A-I
chr5_-_135290705 0.01 ENST00000274507.1
LECT2
leukocyte cell-derived chemotaxin 2
chr2_-_152830441 0.01 ENST00000534999.1
ENST00000397327.2
CACNB4
calcium channel, voltage-dependent, beta 4 subunit
chr2_-_152830479 0.01 ENST00000360283.6
CACNB4
calcium channel, voltage-dependent, beta 4 subunit
chr1_-_27240455 0.00 ENST00000254227.3
NR0B2
nuclear receptor subfamily 0, group B, member 2

Network of associatons between targets according to the STRING database.

First level regulatory network of GATA6

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.7 GO:0060741 prostate gland stromal morphogenesis(GO:0060741)
0.5 2.1 GO:0060585 nitric oxide transport(GO:0030185) negative regulation of nitric-oxide synthase biosynthetic process(GO:0051771) regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585)
0.4 3.6 GO:0000821 regulation of arginine metabolic process(GO:0000821)
0.3 0.8 GO:0038162 erythropoietin-mediated signaling pathway(GO:0038162)
0.2 0.7 GO:0007057 spindle assembly involved in female meiosis I(GO:0007057)
0.2 1.2 GO:0098707 ferrous iron import into cell(GO:0097460) ferrous iron import across plasma membrane(GO:0098707)
0.2 0.6 GO:0060796 regulation of transcription involved in primary germ layer cell fate commitment(GO:0060796)
0.2 0.5 GO:1901301 regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.2 1.7 GO:2000189 positive regulation of cholesterol homeostasis(GO:2000189)
0.2 2.3 GO:0006782 protoporphyrinogen IX biosynthetic process(GO:0006782)
0.2 1.1 GO:0044333 Wnt signaling pathway involved in digestive tract morphogenesis(GO:0044333)
0.1 2.0 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.1 0.7 GO:0001880 Mullerian duct regression(GO:0001880)
0.1 0.3 GO:0098939 dendritic transport of mitochondrion(GO:0098939) anterograde dendritic transport of mitochondrion(GO:0098972)
0.1 0.3 GO:1904479 negative regulation of intestinal absorption(GO:1904479)
0.1 1.0 GO:0015691 cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574)
0.1 0.3 GO:0031133 regulation of axon diameter(GO:0031133)
0.1 0.1 GO:0046882 negative regulation of B cell differentiation(GO:0045578) negative regulation of follicle-stimulating hormone secretion(GO:0046882)
0.1 1.0 GO:0035372 protein localization to microtubule(GO:0035372)
0.0 1.6 GO:0032354 response to follicle-stimulating hormone(GO:0032354)
0.0 0.3 GO:0032971 regulation of muscle filament sliding(GO:0032971)
0.0 0.5 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.0 0.2 GO:0031860 telomeric 3' overhang formation(GO:0031860)
0.0 0.6 GO:0023041 neuronal signal transduction(GO:0023041)
0.0 0.2 GO:0032252 secretory granule localization(GO:0032252)
0.0 0.8 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.0 0.5 GO:0019532 oxalate transport(GO:0019532)
0.0 0.2 GO:0071918 urea transmembrane transport(GO:0071918)
0.0 0.2 GO:0070995 NADPH oxidation(GO:0070995)
0.0 0.2 GO:0006701 progesterone biosynthetic process(GO:0006701)
0.0 0.6 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.0 0.2 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.0 0.4 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.0 0.8 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.0 0.2 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
0.0 1.6 GO:0007405 neuroblast proliferation(GO:0007405)
0.0 0.9 GO:2000144 positive regulation of DNA-templated transcription, initiation(GO:2000144)
0.0 0.2 GO:0060088 auditory receptor cell stereocilium organization(GO:0060088)
0.0 0.3 GO:0007597 blood coagulation, intrinsic pathway(GO:0007597)
0.0 0.2 GO:0031284 positive regulation of guanylate cyclase activity(GO:0031284)
0.0 0.7 GO:0045687 positive regulation of glial cell differentiation(GO:0045687)
0.0 0.2 GO:0071340 activation-induced cell death of T cells(GO:0006924) skeletal muscle acetylcholine-gated channel clustering(GO:0071340)
0.0 0.2 GO:0006477 protein sulfation(GO:0006477)
0.0 0.4 GO:0048665 neuron fate specification(GO:0048665)
0.0 0.4 GO:1901798 positive regulation of signal transduction by p53 class mediator(GO:1901798)
0.0 0.2 GO:0015671 oxygen transport(GO:0015671)
0.0 0.5 GO:0051894 positive regulation of focal adhesion assembly(GO:0051894)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.1 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.2 0.7 GO:0042585 germinal vesicle(GO:0042585)
0.1 0.5 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.1 1.2 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.1 0.3 GO:0005863 striated muscle myosin thick filament(GO:0005863)
0.1 2.0 GO:0043194 axon initial segment(GO:0043194)
0.1 1.6 GO:1990023 mitotic spindle midzone(GO:1990023)
0.0 0.1 GO:0043511 inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.0 0.6 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 0.9 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.0 0.3 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.0 0.7 GO:0071141 SMAD protein complex(GO:0071141)
0.0 0.3 GO:0031595 nuclear proteasome complex(GO:0031595)
0.0 0.2 GO:0005833 hemoglobin complex(GO:0005833)
0.0 0.2 GO:0030870 Mre11 complex(GO:0030870)
0.0 0.2 GO:0000137 Golgi cis cisterna(GO:0000137)
0.0 0.5 GO:0031304 intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305)
0.0 0.8 GO:0005762 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 0.2 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0 0.2 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.1 GO:0031708 endothelin B receptor binding(GO:0031708)
0.3 1.2 GO:0004998 transferrin receptor activity(GO:0004998)
0.2 0.6 GO:0038131 neuregulin receptor activity(GO:0038131)
0.2 3.6 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.1 0.4 GO:0004852 uroporphyrinogen-III synthase activity(GO:0004852)
0.1 0.8 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.1 2.7 GO:0003680 AT DNA binding(GO:0003680)
0.1 0.5 GO:0042015 interleukin-20 binding(GO:0042015)
0.1 0.7 GO:0035174 histone serine kinase activity(GO:0035174)
0.1 2.0 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.1 0.6 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0 1.1 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.3 GO:0015057 thrombin receptor activity(GO:0015057)
0.0 0.3 GO:0016936 galactoside binding(GO:0016936)
0.0 0.7 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.0 0.4 GO:0097322 7SK snRNA binding(GO:0097322)
0.0 0.5 GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634)
0.0 1.7 GO:0005504 fatty acid binding(GO:0005504)
0.0 0.2 GO:0099580 ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.0 0.2 GO:0015265 urea channel activity(GO:0015265)
0.0 0.5 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 0.3 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.0 0.2 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0 0.4 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.5 GO:0005537 mannose binding(GO:0005537)
0.0 1.0 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.2 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.0 0.1 GO:0034711 inhibin binding(GO:0034711)
0.0 0.2 GO:0051880 G-quadruplex DNA binding(GO:0051880)
0.0 0.3 GO:0032036 myosin heavy chain binding(GO:0032036)
0.0 1.7 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765)
0.0 0.1 GO:0030250 cyclase activator activity(GO:0010853) guanylate cyclase activator activity(GO:0030250)
0.0 2.3 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.2 GO:0005344 oxygen transporter activity(GO:0005344)
0.0 0.3 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.1 GO:0004517 nitric-oxide synthase activity(GO:0004517)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.8 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0 0.7 PID ALK2 PATHWAY ALK2 signaling events
0.0 2.1 PID ENDOTHELIN PATHWAY Endothelins
0.0 1.7 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 1.2 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 1.2 PID ILK PATHWAY Integrin-linked kinase signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.3 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.1 1.8 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1 3.6 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 2.1 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 1.7 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.8 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 1.0 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.6 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.3 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.0 0.7 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.3 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.0 0.5 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.1 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.0 1.4 REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1 Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1