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SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for GAUAUGU

Z-value: 0.19

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miRNA associated with seed GAUAUGU

NamemiRBASE accession
hsa-miR-190a-5p
MIMAT0000458
hsa-miR-190b
MIMAT0004929

Activity profile of GAUAUGU motif

Sorted Z-values of GAUAUGU motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr5_+_175223313 0.89 ENST00000359546.4
CPLX2
complexin 2
chr12_-_31744031 0.19 ENST00000389082.5
DENND5B
DENN/MADD domain containing 5B
chr3_-_126076264 0.16 ENST00000296233.3
KLF15
Kruppel-like factor 15
chr19_-_5340730 0.15 ENST00000372412.4
ENST00000357368.4
ENST00000262963.6
ENST00000348075.2
ENST00000353284.2
PTPRS
protein tyrosine phosphatase, receptor type, S
chr20_-_48099182 0.14 ENST00000371741.4
KCNB1
potassium voltage-gated channel, Shab-related subfamily, member 1
chr11_-_70507901 0.14 ENST00000449833.2
ENST00000357171.3
ENST00000449116.2
SHANK2
SH3 and multiple ankyrin repeat domains 2
chr2_+_228336849 0.13 ENST00000409979.2
ENST00000310078.8
AGFG1
ArfGAP with FG repeats 1
chr11_-_31839488 0.12 ENST00000419022.1
ENST00000379132.3
ENST00000379129.2
PAX6
paired box 6
chr19_-_33793430 0.11 ENST00000498907.2
CEBPA
CCAAT/enhancer binding protein (C/EBP), alpha
chr14_+_79745746 0.10 ENST00000281127.7
NRXN3
neurexin 3
chr3_+_173116225 0.10 ENST00000457714.1
NLGN1
neuroligin 1
chr2_-_182545603 0.09 ENST00000295108.3
NEUROD1
neuronal differentiation 1
chr3_+_11314099 0.09 ENST00000446450.2
ENST00000354956.5
ENST00000354449.3
ENST00000419112.1
ATG7
autophagy related 7
chr5_-_45696253 0.08 ENST00000303230.4
HCN1
hyperpolarization activated cyclic nucleotide-gated potassium channel 1
chr10_-_131762105 0.08 ENST00000368648.3
ENST00000355311.5
EBF3
early B-cell factor 3
chr8_-_23712312 0.08 ENST00000290271.2
STC1
stanniocalcin 1
chr8_-_141645645 0.08 ENST00000519980.1
ENST00000220592.5
AGO2
argonaute RISC catalytic component 2
chr1_-_212004090 0.08 ENST00000366997.4
LPGAT1
lysophosphatidylglycerol acyltransferase 1
chr2_-_197457335 0.08 ENST00000260983.3
HECW2
HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2
chr11_-_30038490 0.05 ENST00000328224.6
KCNA4
potassium voltage-gated channel, shaker-related subfamily, member 4
chr7_+_24612935 0.05 ENST00000222644.5
MPP6
membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6)
chr13_-_103053946 0.05 ENST00000376131.4
FGF14
fibroblast growth factor 14
chr15_-_68498376 0.04 ENST00000540479.1
ENST00000395465.3
CALML4
calmodulin-like 4
chr1_+_145470504 0.04 ENST00000323397.4
ANKRD34A
ankyrin repeat domain 34A
chr6_-_91006461 0.04 ENST00000257749.4
ENST00000343122.3
ENST00000406998.2
ENST00000453877.1
BACH2
BTB and CNC homology 1, basic leucine zipper transcription factor 2
chr2_+_149402553 0.04 ENST00000258484.6
ENST00000409654.1
EPC2
enhancer of polycomb homolog 2 (Drosophila)
chr13_+_49550015 0.03 ENST00000492622.2
FNDC3A
fibronectin type III domain containing 3A
chr12_-_102874416 0.03 ENST00000392904.1
ENST00000337514.6
IGF1
insulin-like growth factor 1 (somatomedin C)
chr18_-_35145593 0.03 ENST00000334919.5
ENST00000591282.1
ENST00000588597.1
CELF4
CUGBP, Elav-like family member 4
chr15_-_72612470 0.03 ENST00000287202.5
CELF6
CUGBP, Elav-like family member 6
chr11_-_106889250 0.02 ENST00000526355.2
GUCY1A2
guanylate cyclase 1, soluble, alpha 2
chr7_-_26240357 0.02 ENST00000354667.4
ENST00000356674.7
HNRNPA2B1
heterogeneous nuclear ribonucleoprotein A2/B1
chr2_+_179059365 0.02 ENST00000190611.4
OSBPL6
oxysterol binding protein-like 6
chr8_-_93115445 0.02 ENST00000523629.1
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr7_+_114055052 0.01 ENST00000462331.1
ENST00000408937.3
ENST00000403559.4
ENST00000350908.4
ENST00000393498.2
ENST00000393495.3
ENST00000378237.3
ENST00000393489.3
FOXP2
forkhead box P2
chr6_+_73331776 0.01 ENST00000370398.1
KCNQ5
potassium voltage-gated channel, KQT-like subfamily, member 5
chr22_+_40573921 0.01 ENST00000454349.2
ENST00000335727.9
TNRC6B
trinucleotide repeat containing 6B
chr10_+_125425871 0.01 ENST00000284674.1
GPR26
G protein-coupled receptor 26
chr6_+_69345166 0.01 ENST00000370598.1
BAI3
brain-specific angiogenesis inhibitor 3
chr3_+_187930719 0.01 ENST00000312675.4
LPP
LIM domain containing preferred translocation partner in lipoma
chr18_+_60382672 0.00 ENST00000400316.4
ENST00000262719.5
PHLPP1
PH domain and leucine rich repeat protein phosphatase 1
chr1_+_61547894 0.00 ENST00000403491.3
NFIA
nuclear factor I/A
chr2_+_114647504 0.00 ENST00000263238.2
ACTR3
ARP3 actin-related protein 3 homolog (yeast)
chr2_-_61765315 0.00 ENST00000406957.1
ENST00000401558.2
XPO1
exportin 1 (CRM1 homolog, yeast)
chr21_-_39870339 0.00 ENST00000429727.2
ENST00000398905.1
ENST00000398907.1
ENST00000453032.2
ENST00000288319.7
ERG
v-ets avian erythroblastosis virus E26 oncogene homolog

Network of associatons between targets according to the STRING database.

First level regulatory network of GAUAUGU

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0034164 negative regulation of toll-like receptor 9 signaling pathway(GO:0034164)
0.0 0.1 GO:0010701 positive regulation of norepinephrine secretion(GO:0010701)
0.0 0.1 GO:0098923 retrograde trans-synaptic signaling by soluble gas(GO:0098923) trans-synaptic signaling by soluble gas(GO:0099543) trans-synaptic signaling by trans-synaptic complex(GO:0099545)
0.0 0.9 GO:0031915 positive regulation of synaptic plasticity(GO:0031915)
0.0 0.1 GO:0060730 regulation of intestinal epithelial structure maintenance(GO:0060730)
0.0 0.1 GO:0039521 lysosomal microautophagy(GO:0016237) piecemeal microautophagy of nucleus(GO:0034727) suppression by virus of host autophagy(GO:0039521)
0.0 0.1 GO:0003322 pancreatic A cell development(GO:0003322)
0.0 0.1 GO:0090625 siRNA loading onto RISC involved in RNA interference(GO:0035087) mRNA cleavage involved in gene silencing by siRNA(GO:0090625)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.9 GO:0070033 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033) synaptobrevin 2-SNAP-25-syntaxin-3-complexin complex(GO:0070554)
0.0 0.1 GO:0098855 HCN channel complex(GO:0098855)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0019778 Atg12 activating enzyme activity(GO:0019778) Atg8 activating enzyme activity(GO:0019779)
0.0 0.1 GO:0098808 mRNA cap binding(GO:0098808)
0.0 0.1 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
0.0 0.9 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.1 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.0 0.2 GO:0035374 chondroitin sulfate binding(GO:0035374)