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SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for GLI3

Z-value: 2.08

Motif logo

Transcription factors associated with GLI3

Gene Symbol Gene ID Gene Info
ENSG00000106571.8 GLI family zinc finger 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
GLI3hg19_v2_chr7_-_42276612_422767820.905.2e-08Click!

Activity profile of GLI3 motif

Sorted Z-values of GLI3 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr1_-_153538292 12.81 ENST00000497140.1
ENST00000368708.3
S100 calcium binding protein A2
chr12_-_52887034 12.06 ENST00000330722.6
keratin 6A
chr18_+_21529811 9.56 ENST00000588004.1
laminin, alpha 3
chr1_+_183155373 8.42 ENST00000493293.1
ENST00000264144.4
laminin, gamma 2
chr1_-_153538011 8.39 ENST00000368707.4
S100 calcium binding protein A2
chr4_-_90758227 8.37 ENST00000506691.1
ENST00000394986.1
ENST00000506244.1
ENST00000394989.2
ENST00000394991.3
synuclein, alpha (non A4 component of amyloid precursor)
chr12_-_52867569 7.33 ENST00000252250.6
keratin 6C
chr19_+_35606692 6.73 ENST00000406242.3
ENST00000454903.2
FXYD domain containing ion transport regulator 3
chr12_-_52845910 6.66 ENST00000252252.3
keratin 6B
chr17_-_39928106 6.64 ENST00000540235.1
junction plakoglobin
chr16_+_68679193 6.44 ENST00000581171.1
cadherin 3, type 1, P-cadherin (placental)
chr19_-_51456344 6.39 ENST00000336334.3
ENST00000593428.1
kallikrein-related peptidase 5
chr1_-_1356628 6.26 ENST00000442470.1
ENST00000537107.1
ankyrin repeat domain 65
chr1_+_152881014 5.71 ENST00000368764.3
ENST00000392667.2
involucrin
chr20_+_62327996 5.51 ENST00000369996.1
tumor necrosis factor receptor superfamily, member 6b, decoy
chr19_-_51456321 5.32 ENST00000391809.2
kallikrein-related peptidase 5
chr16_+_68678739 5.20 ENST00000264012.4
cadherin 3, type 1, P-cadherin (placental)
chr21_-_28215332 5.11 ENST00000517777.1
ADAM metallopeptidase with thrombospondin type 1 motif, 1
chr11_-_118550375 5.06 ENST00000525958.1
ENST00000264029.4
ENST00000397925.1
ENST00000529101.1
trehalase (brush-border membrane glycoprotein)
chr6_-_32784687 4.85 ENST00000447394.1
ENST00000438763.2
major histocompatibility complex, class II, DO beta
chr3_-_195538760 4.84 ENST00000475231.1
mucin 4, cell surface associated
chr11_-_119187826 4.79 ENST00000264036.4
melanoma cell adhesion molecule
chr16_+_55522536 4.74 ENST00000570283.1
matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
chr20_-_1306351 4.59 ENST00000381812.1
syndecan binding protein (syntenin) 2
chr8_+_124194752 4.58 ENST00000318462.6
family with sequence similarity 83, member A
chrX_-_100914781 4.50 ENST00000431597.1
ENST00000458024.1
ENST00000413506.1
ENST00000440675.1
ENST00000328766.5
ENST00000356824.4
armadillo repeat containing, X-linked 2
chr8_+_124194875 4.48 ENST00000522648.1
ENST00000276699.6
family with sequence similarity 83, member A
chr16_-_68269971 4.32 ENST00000565858.1
epithelial splicing regulatory protein 2
chr3_-_195538728 4.21 ENST00000349607.4
ENST00000346145.4
mucin 4, cell surface associated
chr1_+_13910194 4.06 ENST00000376057.4
ENST00000510906.1
podoplanin
chr12_-_54779511 4.04 ENST00000551109.1
ENST00000546970.1
zinc finger protein 385A
chr20_-_1306391 4.01 ENST00000339987.3
syndecan binding protein (syntenin) 2
chr13_-_20767037 3.98 ENST00000382848.4
gap junction protein, beta 2, 26kDa
chr19_-_20844368 3.96 ENST00000595094.1
ENST00000601440.1
ENST00000291750.6
CTC-513N18.7
zinc finger protein 626
chr1_-_160990886 3.94 ENST00000537746.1
F11 receptor
chr20_+_44098385 3.92 ENST00000217425.5
ENST00000339946.3
WAP four-disulfide core domain 2
chr1_-_209792111 3.86 ENST00000455193.1
laminin, beta 3
chr5_-_149792295 3.85 ENST00000518797.1
ENST00000524315.1
ENST00000009530.7
ENST00000377795.3
CD74 molecule, major histocompatibility complex, class II invariant chain
chr19_+_48281842 3.67 ENST00000509570.2
selenoprotein W, 1
chr1_+_36789335 3.58 ENST00000373137.2
RP11-268J15.5
chr20_+_44637526 3.55 ENST00000372330.3
matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)
chr5_+_9546306 3.55 ENST00000508179.1
small nucleolar RNA host gene 18 (non-protein coding)
chr19_-_53324884 3.51 ENST00000457749.2
ENST00000414252.2
ENST00000391783.2
zinc finger protein 28
chr1_+_156123359 3.49 ENST00000368284.1
ENST00000368286.2
ENST00000438830.1
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
chr16_-_2908155 3.45 ENST00000571228.1
ENST00000161006.3
protease, serine, 22
chr19_-_51456198 3.42 ENST00000594846.1
kallikrein-related peptidase 5
chr1_+_152956549 3.42 ENST00000307122.2
small proline-rich protein 1A
chr7_-_41742697 3.39 ENST00000242208.4
inhibin, beta A
chr12_-_57634475 3.34 ENST00000393825.1
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2
chr19_-_35323762 3.33 ENST00000590963.1
CTC-523E23.4
chrX_+_135618258 3.32 ENST00000440515.1
ENST00000456412.1
vestigial like 1 (Drosophila)
chr1_-_85358850 3.31 ENST00000370611.3
lysophosphatidic acid receptor 3
chr20_+_44098346 3.29 ENST00000372676.3
WAP four-disulfide core domain 2
chr11_-_119991589 3.27 ENST00000526881.1
tripartite motif containing 29
chr1_-_1356719 3.24 ENST00000520296.1
ankyrin repeat domain 65
chr19_-_11689752 3.24 ENST00000592659.1
ENST00000592828.1
ENST00000218758.5
ENST00000412435.2
acid phosphatase 5, tartrate resistant
chr16_+_2880157 3.22 ENST00000382280.3
zymogen granule protein 16B
chr1_+_44399347 3.21 ENST00000477048.1
ENST00000471394.2
artemin
chr1_-_201368707 3.21 ENST00000391967.2
ladinin 1
chr19_-_51472031 3.18 ENST00000391808.1
kallikrein-related peptidase 6
chr6_-_159420780 3.14 ENST00000449822.1
radial spoke 3 homolog (Chlamydomonas)
chr21_-_33984456 3.12 ENST00000431216.1
ENST00000553001.1
ENST00000440966.1
Uncharacterized protein
chromosome 21 open reading frame 59
chr16_+_68771128 3.08 ENST00000261769.5
ENST00000422392.2
cadherin 1, type 1, E-cadherin (epithelial)
chr8_+_143761874 3.08 ENST00000301258.4
ENST00000513264.1
prostate stem cell antigen
chr15_-_45422056 3.08 ENST00000267803.4
ENST00000559014.1
ENST00000558851.1
ENST00000559988.1
ENST00000558996.1
ENST00000558422.1
ENST00000559226.1
ENST00000558326.1
ENST00000558377.1
ENST00000559644.1
dual oxidase maturation factor 1
chr11_-_111783919 3.07 ENST00000531198.1
ENST00000533879.1
crystallin, alpha B
chr15_+_45422178 3.04 ENST00000389037.3
ENST00000558322.1
dual oxidase 1
chr22_-_38349552 3.01 ENST00000422191.1
ENST00000249079.2
ENST00000418863.1
ENST00000403305.1
ENST00000403026.1
chromosome 22 open reading frame 23
chr5_-_95297678 2.99 ENST00000237853.4
elongation factor, RNA polymerase II, 2
chr5_-_180237445 2.98 ENST00000393340.3
mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
chrX_+_115567767 2.97 ENST00000371900.4
solute carrier family 6 (amino acid transporter), member 14
chr22_+_38035623 2.93 ENST00000336738.5
ENST00000442465.2
SH3-domain binding protein 1
chr1_+_35220613 2.92 ENST00000338513.1
gap junction protein, beta 5, 31.1kDa
chr7_-_92465868 2.92 ENST00000424848.2
cyclin-dependent kinase 6
chr6_-_29648887 2.90 ENST00000376883.1
ZFP57 zinc finger protein
chr7_-_121784285 2.89 ENST00000417368.2
aminoadipate-semialdehyde synthase
chr1_+_40942887 2.86 ENST00000372706.1
ZFP69 zinc finger protein
chr19_-_2050852 2.84 ENST00000541165.1
ENST00000591601.1
MAP kinase interacting serine/threonine kinase 2
chr12_-_57030096 2.84 ENST00000549506.1
bromodomain adjacent to zinc finger domain, 2A
chr11_-_65640325 2.80 ENST00000307998.6
EGF containing fibulin-like extracellular matrix protein 2
chrX_-_7895755 2.78 ENST00000444736.1
ENST00000537427.1
ENST00000442940.1
patatin-like phospholipase domain containing 4
chr10_-_27444143 2.78 ENST00000477432.1
YME1-like 1 ATPase
chr1_+_44399466 2.78 ENST00000498139.2
ENST00000491846.1
artemin
chr10_+_88718314 2.76 ENST00000348795.4
synuclein, gamma (breast cancer-specific protein 1)
chr14_-_61748550 2.75 ENST00000555868.1
transmembrane protein 30B
chr10_-_105615164 2.73 ENST00000355946.2
ENST00000369774.4
SH3 and PX domains 2A
chr5_+_148960931 2.72 ENST00000333677.6
Rho guanine nucleotide exchange factor (GEF) 37
chr5_-_95297534 2.72 ENST00000513343.1
ENST00000431061.2
elongation factor, RNA polymerase II, 2
chr19_-_35992780 2.69 ENST00000593342.1
ENST00000601650.1
ENST00000408915.2
dermokine
chr15_+_45422131 2.67 ENST00000321429.4
dual oxidase 1
chr1_-_62785054 2.66 ENST00000371153.4
KN motif and ankyrin repeat domains 4
chr1_-_31845914 2.65 ENST00000373713.2
fatty acid binding protein 3, muscle and heart (mammary-derived growth inhibitor)
chr11_-_12030681 2.64 ENST00000529338.1
dickkopf WNT signaling pathway inhibitor 3
chrX_+_152086373 2.64 ENST00000318529.8
zinc finger protein 185 (LIM domain)
chr1_+_3388181 2.61 ENST00000418137.1
ENST00000413250.2
Rho guanine nucleotide exchange factor (GEF) 16
chr22_+_31644388 2.60 ENST00000333611.4
ENST00000340552.4
LIM domain kinase 2
chr5_+_9546376 2.59 ENST00000509788.1
small nucleolar RNA host gene 18 (non-protein coding)
chr9_+_124413873 2.58 ENST00000408936.3
DAB2 interacting protein
chr19_+_49713991 2.56 ENST00000597316.1
transient receptor potential cation channel, subfamily M, member 4
chr14_+_72052983 2.54 ENST00000358550.2
signal-induced proliferation-associated 1 like 1
chr1_+_150521876 2.53 ENST00000369041.5
ENST00000271643.4
ENST00000538795.1
ADAMTS-like 4
Protein LOC100996516
chr19_+_52873166 2.49 ENST00000424032.2
ENST00000600321.1
ENST00000344085.5
ENST00000597976.1
ENST00000422689.2
zinc finger protein 880
chr11_+_46403303 2.48 ENST00000407067.1
ENST00000395565.1
midkine (neurite growth-promoting factor 2)
chr17_-_34122596 2.48 ENST00000250144.8
matrix metallopeptidase 28
chrX_-_7895479 2.47 ENST00000381042.4
patatin-like phospholipase domain containing 4
chr8_+_94929168 2.45 ENST00000518107.1
ENST00000396200.3
pyruvate dehyrogenase phosphatase catalytic subunit 1
chr7_-_994302 2.44 ENST00000265846.5
ArfGAP with dual PH domains 1
chr10_+_88718397 2.44 ENST00000372017.3
synuclein, gamma (breast cancer-specific protein 1)
chr3_-_128840604 2.44 ENST00000476465.1
ENST00000315150.5
ENST00000393304.1
ENST00000393308.1
ENST00000393307.1
ENST00000393305.1
RAB43, member RAS oncogene family
chr11_+_5712234 2.43 ENST00000414641.1
tripartite motif containing 22
chr1_-_22215192 2.42 ENST00000374673.3
heparan sulfate proteoglycan 2
chr9_-_122131696 2.41 ENST00000373964.2
ENST00000265922.3
bone morphogenetic protein/retinoic acid inducible neural-specific 1
chr8_+_94929077 2.41 ENST00000297598.4
ENST00000520614.1
pyruvate dehyrogenase phosphatase catalytic subunit 1
chr11_-_12030130 2.40 ENST00000450094.2
ENST00000534511.1
dickkopf WNT signaling pathway inhibitor 3
chr19_+_38810447 2.40 ENST00000263372.3
potassium channel, subfamily K, member 6
chr1_-_95285764 2.37 ENST00000414374.1
ENST00000421997.1
ENST00000418366.2
ENST00000452922.1
long intergenic non-protein coding RNA 1057
chr9_-_101017862 2.37 ENST00000375064.1
ENST00000342112.5
TBC1 domain family, member 2
chr1_+_150522222 2.35 ENST00000369039.5
ADAMTS-like 4
chr14_-_24729251 2.32 ENST00000559136.1
transglutaminase 1
chr3_-_176914998 2.32 ENST00000431421.1
ENST00000422066.1
ENST00000413084.1
transducin (beta)-like 1 X-linked receptor 1
chr19_+_48281803 2.31 ENST00000601048.1
selenoprotein W, 1
chr21_-_47604318 2.29 ENST00000291672.5
ENST00000330205.6
spermatogenesis and centriole associated 1-like
chr21_-_45079341 2.27 ENST00000443485.1
ENST00000291560.2
heat shock transcription factor 2 binding protein
chr9_-_101017900 2.26 ENST00000375066.5
TBC1 domain family, member 2
chr19_-_51522955 2.25 ENST00000358789.3
kallikrein-related peptidase 10
chr11_-_12030629 2.24 ENST00000396505.2
dickkopf WNT signaling pathway inhibitor 3
chr11_-_568369 2.23 ENST00000534540.1
ENST00000528245.1
ENST00000500447.1
ENST00000533920.1
MIR210 host gene (non-protein coding)
chr22_+_25465786 2.23 ENST00000401395.1
KIAA1671
chr15_-_72490114 2.22 ENST00000309731.7
GRAM domain containing 2
chr8_+_94929110 2.21 ENST00000520728.1
pyruvate dehyrogenase phosphatase catalytic subunit 1
chr3_+_38035610 2.18 ENST00000465644.1
villin-like
chr16_+_4526341 2.17 ENST00000458134.3
ENST00000219700.6
ENST00000575120.1
ENST00000572812.1
ENST00000574466.1
ENST00000576827.1
ENST00000570445.1
heme oxygenase (decycling) 2
chr1_+_156123318 2.13 ENST00000368285.3
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
chr3_-_176915036 2.13 ENST00000427349.1
ENST00000352800.5
transducin (beta)-like 1 X-linked receptor 1
chr20_-_50808236 2.11 ENST00000361387.2
ZFP64 zinc finger protein
chr5_+_150157444 2.10 ENST00000526627.1
small integral membrane protein 3
chr11_+_32851487 2.10 ENST00000257836.3
proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)
chr6_+_43739697 2.10 ENST00000230480.6
vascular endothelial growth factor A
chr21_-_33985127 2.09 ENST00000290155.3
chromosome 21 open reading frame 59
chr6_-_134373732 2.08 ENST00000275230.5
solute carrier family 2 (facilitated glucose transporter), member 12
chr1_+_26605618 2.08 ENST00000270792.5
SH3 domain binding glutamic acid-rich protein like 3
chr19_+_21688366 2.07 ENST00000358491.4
ENST00000597078.1
zinc finger protein 429
chr16_+_3115611 2.07 ENST00000530890.1
ENST00000444393.3
ENST00000533097.2
ENST00000008180.9
ENST00000396890.2
ENST00000525228.1
ENST00000548652.1
ENST00000525377.2
ENST00000530538.2
ENST00000549213.1
ENST00000552936.1
ENST00000548476.1
ENST00000552664.1
ENST00000552356.1
ENST00000551513.1
ENST00000382213.3
ENST00000548246.1
interleukin 32
chr12_-_8814669 2.06 ENST00000535411.1
ENST00000540087.1
microfibrillar associated protein 5
chr2_-_85636928 2.06 ENST00000449030.1
capping protein (actin filament), gelsolin-like
chr3_-_16554403 2.06 ENST00000449415.1
ENST00000441460.1
raftlin, lipid raft linker 1
chr19_-_2051223 2.04 ENST00000309340.7
ENST00000589534.1
ENST00000250896.3
ENST00000589509.1
MAP kinase interacting serine/threonine kinase 2
chr1_+_203595903 2.04 ENST00000367218.3
ENST00000367219.3
ENST00000391954.2
ATPase, Ca++ transporting, plasma membrane 4
chr1_+_36554470 2.01 ENST00000373178.4
ADP-ribosylhydrolase like 2
chr11_-_118789613 1.99 ENST00000532899.1
B-cell CLL/lymphoma 9-like
chr21_-_33984888 1.98 ENST00000382549.4
ENST00000540881.1
chromosome 21 open reading frame 59
chr8_-_119634141 1.98 ENST00000409003.4
ENST00000526328.1
ENST00000314727.4
ENST00000526765.1
sterile alpha motif domain containing 12
chr12_-_13529642 1.98 ENST00000318426.2
chromosome 12 open reading frame 36
chr17_+_36584662 1.97 ENST00000431231.2
ENST00000437668.3
Rho GTPase activating protein 23
chr12_-_120687948 1.97 ENST00000458477.2
paxillin
chr17_+_8339340 1.97 ENST00000580012.1
nudE neurodevelopment protein 1-like 1
chr20_-_6104191 1.93 ENST00000217289.4
fermitin family member 1
chr12_-_48276710 1.93 ENST00000550314.1
vitamin D (1,25- dihydroxyvitamin D3) receptor
chr11_-_65640198 1.93 ENST00000528176.1
EGF containing fibulin-like extracellular matrix protein 2
chr12_-_54813229 1.92 ENST00000293379.4
integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
chr1_-_20834586 1.92 ENST00000264198.3
mitochondrial E3 ubiquitin protein ligase 1
chr17_-_4463856 1.91 ENST00000574584.1
ENST00000381550.3
ENST00000301395.3
gamma-glutamyltransferase 6
chr19_-_20748541 1.91 ENST00000427401.4
ENST00000594419.1
zinc finger protein 737
chr16_+_27325202 1.90 ENST00000395762.2
ENST00000562142.1
ENST00000561742.1
ENST00000543915.2
ENST00000449195.1
ENST00000380922.3
ENST00000563002.1
interleukin 4 receptor
chr11_-_13484713 1.90 ENST00000526841.1
ENST00000529708.1
ENST00000278174.5
ENST00000528120.1
BTB (POZ) domain containing 10
chr19_-_23578220 1.90 ENST00000595533.1
ENST00000397082.2
ENST00000599743.1
ENST00000300619.7
zinc finger protein 91
chr9_+_112542591 1.90 ENST00000483909.1
ENST00000314527.4
ENST00000413420.1
ENST00000302798.7
ENST00000555236.1
ENST00000510514.5
paralemmin 2
PALM2-AKAP2 readthrough
A kinase (PRKA) anchor protein 2
chr5_-_42825983 1.89 ENST00000506577.1
selenoprotein P, plasma, 1
chr9_-_139891165 1.89 ENST00000494426.1
chloride intracellular channel 3
chr9_+_135937365 1.89 ENST00000372080.4
ENST00000351304.7
carboxyl ester lipase
chr14_+_94577074 1.88 ENST00000444961.1
ENST00000448882.1
ENST00000557098.1
ENST00000554800.1
ENST00000556544.1
ENST00000298902.5
ENST00000555819.1
ENST00000557634.1
ENST00000555744.1
interferon, alpha-inducible protein 27
chr15_-_101084547 1.87 ENST00000394113.1
ceramide synthase 3
chr2_+_131769256 1.86 ENST00000355771.3
Rho guanine nucleotide exchange factor (GEF) 4
chr19_-_2041159 1.86 ENST00000589441.1
MAP kinase interacting serine/threonine kinase 2
chr10_-_97050777 1.86 ENST00000329399.6
PDZ and LIM domain 1
chr13_-_20806440 1.85 ENST00000400066.3
ENST00000400065.3
ENST00000356192.6
gap junction protein, beta 6, 30kDa
chr6_+_27356745 1.83 ENST00000461521.1
zinc finger protein 391
chr11_+_111412053 1.83 ENST00000530962.1
layilin
chr11_-_111784005 1.82 ENST00000527899.1
crystallin, alpha B
chr13_+_115047097 1.82 ENST00000351487.5
UPF3 regulator of nonsense transcripts homolog A (yeast)
chr9_-_34458531 1.81 ENST00000379089.1
ENST00000379087.1
ENST00000379084.1
ENST00000379081.1
ENST00000379080.1
ENST00000422409.1
ENST00000379078.1
ENST00000445726.1
ENST00000297620.4
family with sequence similarity 219, member A
chr1_+_220701740 1.80 ENST00000366917.4
MAP/microtubule affinity-regulating kinase 1
chr14_+_29236269 1.79 ENST00000313071.4
forkhead box G1
chr11_+_18230727 1.77 ENST00000527059.1
Putative mitochondrial carrier protein LOC494141
chr11_-_111783595 1.77 ENST00000528628.1
crystallin, alpha B
chr6_-_33548006 1.75 ENST00000374467.3
BCL2-antagonist/killer 1
chr4_-_177713788 1.75 ENST00000280193.2
vascular endothelial growth factor C
chr2_-_264772 1.75 ENST00000403658.1
ENST00000402632.1
ENST00000415368.1
ENST00000454318.1
SH3 and SYLF domain containing 1
chr12_-_54778471 1.75 ENST00000550120.1
ENST00000394313.2
ENST00000547210.1
zinc finger protein 385A
chr8_+_96146168 1.75 ENST00000519516.1
pleckstrin homology domain containing, family F (with FYVE domain) member 2
chr19_+_2096868 1.73 ENST00000395296.1
ENST00000395301.3
IZUMO family member 4
chr10_+_11060004 1.73 ENST00000542579.1
ENST00000399850.3
ENST00000417956.2
CUGBP, Elav-like family member 2
chr2_-_201936302 1.73 ENST00000453765.1
ENST00000452799.1
ENST00000446678.1
ENST00000418596.3
family with sequence similarity 126, member B
chr11_+_46403194 1.72 ENST00000395569.4
ENST00000395566.4
midkine (neurite growth-promoting factor 2)
chrX_-_52683950 1.71 ENST00000298181.5
synovial sarcoma, X breakpoint 7
chr1_-_152386732 1.71 ENST00000271835.3
cornulin
chr3_+_186648307 1.71 ENST00000457772.2
ENST00000455441.1
ENST00000427315.1
ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
chr12_-_57030115 1.70 ENST00000379441.3
ENST00000179765.5
ENST00000551812.1
bromodomain adjacent to zinc finger domain, 2A
chr1_+_40420802 1.70 ENST00000372811.5
ENST00000420632.2
ENST00000434861.1
ENST00000372809.5
major facilitator superfamily domain containing 2A
chr6_-_167040693 1.69 ENST00000366863.2
ribosomal protein S6 kinase, 90kDa, polypeptide 2

Network of associatons between targets according to the STRING database.

First level regulatory network of GLI3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
3.0 12.1 GO:0051710 cytolysis by symbiont of host cells(GO:0001897) regulation of cytolysis in other organism(GO:0051710)
2.9 11.6 GO:1902910 regulation of monophenol monooxygenase activity(GO:0032771) positive regulation of monophenol monooxygenase activity(GO:0032773) negative regulation of catagen(GO:0051796) regulation of hair cycle by canonical Wnt signaling pathway(GO:0060901) positive regulation of melanosome transport(GO:1902910)
2.5 15.1 GO:0002803 positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antimicrobial humoral response(GO:0002760) positive regulation of antibacterial peptide production(GO:0002803)
1.8 3.6 GO:0048817 negative regulation of hair follicle maturation(GO:0048817)
1.7 8.4 GO:2000470 negative regulation of dopamine uptake involved in synaptic transmission(GO:0051585) norepinephrine uptake(GO:0051620) regulation of norepinephrine uptake(GO:0051621) negative regulation of norepinephrine uptake(GO:0051622) negative regulation of catecholamine uptake involved in synaptic transmission(GO:0051945) regulation of glutathione peroxidase activity(GO:1903282) positive regulation of glutathione peroxidase activity(GO:1903284) positive regulation of hydrogen peroxide catabolic process(GO:1903285) positive regulation of peroxidase activity(GO:2000470)
1.6 4.8 GO:0002581 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581)
1.4 4.1 GO:1904328 regulation of myofibroblast contraction(GO:1904328) myofibroblast contraction(GO:1990764)
1.2 8.5 GO:1902162 mRNA localization resulting in posttranscriptional regulation of gene expression(GO:0010609) regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902162) positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902164)
1.1 3.4 GO:0002352 B cell negative selection(GO:0002352) post-embryonic camera-type eye morphogenesis(GO:0048597)
1.1 3.4 GO:0060279 regulation of ovulation(GO:0060278) positive regulation of ovulation(GO:0060279)
1.0 5.0 GO:0018153 isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine(GO:0018153) isopeptide cross-linking(GO:0018262)
1.0 6.0 GO:0097021 lymphocyte migration into lymphoid organs(GO:0097021)
1.0 5.7 GO:0042335 cuticle development(GO:0042335)
0.9 6.6 GO:0071603 endothelial cell-cell adhesion(GO:0071603)
0.9 7.3 GO:1902613 regulation of anti-Mullerian hormone signaling pathway(GO:1902612) negative regulation of anti-Mullerian hormone signaling pathway(GO:1902613) anti-Mullerian hormone signaling pathway(GO:1990262)
0.9 3.5 GO:1903381 neuron intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress(GO:0036483) regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903381) negative regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903382)
0.9 5.2 GO:0030421 defecation(GO:0030421)
0.9 4.3 GO:0032796 uropod organization(GO:0032796)
0.8 2.5 GO:0051562 negative regulation of mitochondrial calcium ion concentration(GO:0051562)
0.8 2.4 GO:0035526 retrograde transport, plasma membrane to Golgi(GO:0035526)
0.8 4.0 GO:0044752 response to human chorionic gonadotropin(GO:0044752)
0.8 3.8 GO:0002901 mature B cell apoptotic process(GO:0002901) regulation of mature B cell apoptotic process(GO:0002905) negative regulation of mature B cell apoptotic process(GO:0002906)
0.7 2.1 GO:1903572 regulation of protein kinase D signaling(GO:1903570) positive regulation of protein kinase D signaling(GO:1903572)
0.7 2.0 GO:1900081 regulation of cellular amine catabolic process(GO:0033241) negative regulation of cellular amine catabolic process(GO:0033242) negative regulation of the force of heart contraction(GO:0098736) regulation of arginine catabolic process(GO:1900081) negative regulation of arginine catabolic process(GO:1900082) regulation of citrulline biosynthetic process(GO:1903248) negative regulation of citrulline biosynthetic process(GO:1903249) negative regulation of cellular amino acid biosynthetic process(GO:2000283)
0.6 24.0 GO:0031581 hemidesmosome assembly(GO:0031581)
0.6 1.9 GO:1903521 apoptotic process involved in mammary gland involution(GO:0060057) positive regulation of apoptotic process involved in mammary gland involution(GO:0060058) positive regulation of apoptotic process involved in morphogenesis(GO:1902339) regulation of mammary gland involution(GO:1903519) positive regulation of mammary gland involution(GO:1903521) positive regulation of apoptotic process involved in development(GO:1904747)
0.6 2.6 GO:1990736 positive regulation of regulation of vascular smooth muscle cell membrane depolarization(GO:1904199) regulation of vascular smooth muscle cell membrane depolarization(GO:1990736)
0.6 1.9 GO:1904404 cellular response to vitamin B1(GO:0071301) response to formaldehyde(GO:1904404)
0.6 2.9 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.6 2.8 GO:0018125 peptidyl-cysteine methylation(GO:0018125)
0.6 5.7 GO:0036072 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.5 2.2 GO:0006788 heme oxidation(GO:0006788)
0.5 2.7 GO:2001245 regulation of phosphatidylcholine biosynthetic process(GO:2001245)
0.5 0.5 GO:0006346 methylation-dependent chromatin silencing(GO:0006346)
0.5 2.6 GO:0043553 vascular endothelial growth factor receptor-2 signaling pathway(GO:0036324) negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.5 1.5 GO:0051102 DNA ligation involved in DNA recombination(GO:0051102)
0.5 4.5 GO:0006049 UDP-N-acetylglucosamine catabolic process(GO:0006049)
0.5 1.5 GO:1990519 pyrimidine nucleotide transport(GO:0006864) mitochondrial pyrimidine nucleotide import(GO:1990519)
0.5 2.9 GO:0033512 L-lysine catabolic process to acetyl-CoA via saccharopine(GO:0033512)
0.5 2.9 GO:0045626 negative regulation of T-helper 1 cell differentiation(GO:0045626)
0.5 1.9 GO:0070895 transposon integration(GO:0070893) regulation of transposon integration(GO:0070894) negative regulation of transposon integration(GO:0070895)
0.5 1.9 GO:0044240 multicellular organism lipid catabolic process(GO:0044240)
0.4 0.9 GO:1904582 regulation of intracellular mRNA localization(GO:1904580) positive regulation of intracellular mRNA localization(GO:1904582)
0.4 1.7 GO:1903778 protein localization to vacuolar membrane(GO:1903778)
0.4 2.5 GO:0010760 negative regulation of macrophage chemotaxis(GO:0010760)
0.4 3.2 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
0.4 2.7 GO:0072675 multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675)
0.4 2.3 GO:0010637 negative regulation of mitochondrial fusion(GO:0010637)
0.4 2.7 GO:1903575 cornified envelope assembly(GO:1903575)
0.4 5.7 GO:0060613 fat pad development(GO:0060613)
0.4 1.9 GO:0002296 T-helper 1 cell lineage commitment(GO:0002296)
0.4 2.3 GO:0034441 plasma lipoprotein particle oxidation(GO:0034441)
0.4 1.9 GO:0044501 modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032)
0.4 3.3 GO:0051549 positive regulation of keratinocyte migration(GO:0051549)
0.4 1.1 GO:0038193 thromboxane A2 signaling pathway(GO:0038193)
0.4 0.7 GO:0006913 nucleocytoplasmic transport(GO:0006913)
0.4 1.5 GO:0018076 N-terminal peptidyl-lysine acetylation(GO:0018076)
0.4 4.0 GO:0071680 response to indole-3-methanol(GO:0071680) cellular response to indole-3-methanol(GO:0071681)
0.4 6.8 GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510) regulation of acyl-CoA biosynthetic process(GO:0050812)
0.3 1.0 GO:0030070 insulin processing(GO:0030070)
0.3 2.8 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
0.3 6.2 GO:0005984 disaccharide metabolic process(GO:0005984)
0.3 1.4 GO:0046338 phosphatidylethanolamine catabolic process(GO:0046338)
0.3 2.7 GO:0030578 PML body organization(GO:0030578)
0.3 4.4 GO:0036066 protein O-linked fucosylation(GO:0036066)
0.3 0.7 GO:2000729 positive regulation of mesenchymal cell proliferation involved in ureter development(GO:2000729)
0.3 1.0 GO:2000620 positive regulation of histone H4-K16 acetylation(GO:2000620)
0.3 2.3 GO:0045229 cell envelope organization(GO:0043163) external encapsulating structure organization(GO:0045229)
0.3 3.0 GO:0003383 apical constriction(GO:0003383)
0.3 2.9 GO:0051533 positive regulation of NFAT protein import into nucleus(GO:0051533)
0.3 0.9 GO:0046707 IDP metabolic process(GO:0046707) IDP catabolic process(GO:0046709)
0.3 1.3 GO:0060084 synaptic transmission involved in micturition(GO:0060084)
0.3 0.9 GO:0002317 plasma cell differentiation(GO:0002317)
0.3 4.6 GO:0061042 vascular wound healing(GO:0061042)
0.3 1.5 GO:1903237 negative regulation of leukocyte tethering or rolling(GO:1903237)
0.3 1.2 GO:1990418 response to insulin-like growth factor stimulus(GO:1990418)
0.3 1.8 GO:0060754 positive regulation of mast cell chemotaxis(GO:0060754)
0.3 2.3 GO:2000609 regulation of thyroid hormone generation(GO:2000609)
0.3 8.2 GO:0071243 cellular response to arsenic-containing substance(GO:0071243)
0.3 0.8 GO:0060370 susceptibility to T cell mediated cytotoxicity(GO:0060370)
0.3 3.3 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.3 1.0 GO:0061357 positive regulation of Wnt protein secretion(GO:0061357)
0.3 7.4 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.3 2.3 GO:2000491 positive regulation of hepatic stellate cell activation(GO:2000491)
0.3 1.3 GO:1905167 positive regulation of lysosomal protein catabolic process(GO:1905167)
0.3 1.5 GO:1900827 maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.2 1.5 GO:1900220 semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220)
0.2 3.0 GO:0060052 neurofilament cytoskeleton organization(GO:0060052)
0.2 1.5 GO:0035063 nuclear speck organization(GO:0035063)
0.2 2.9 GO:1904628 response to phorbol 13-acetate 12-myristate(GO:1904627) cellular response to phorbol 13-acetate 12-myristate(GO:1904628)
0.2 1.0 GO:0046947 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.2 1.2 GO:0016240 autophagosome docking(GO:0016240)
0.2 4.8 GO:0001542 ovulation from ovarian follicle(GO:0001542)
0.2 0.7 GO:0033341 regulation of collagen binding(GO:0033341)
0.2 0.9 GO:0046166 glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
0.2 1.6 GO:0051012 microtubule sliding(GO:0051012)
0.2 0.7 GO:1901301 regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.2 1.3 GO:1904219 regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) positive regulation of serine C-palmitoyltransferase activity(GO:1904222)
0.2 0.7 GO:2000118 regulation of sodium-dependent phosphate transport(GO:2000118)
0.2 0.9 GO:0030262 cellular component disassembly involved in execution phase of apoptosis(GO:0006921) apoptotic nuclear changes(GO:0030262)
0.2 0.9 GO:0019417 sulfur oxidation(GO:0019417)
0.2 0.6 GO:0044209 AMP salvage(GO:0044209)
0.2 1.5 GO:0010025 wax biosynthetic process(GO:0010025) wax metabolic process(GO:0010166)
0.2 5.3 GO:0007021 tubulin complex assembly(GO:0007021)
0.2 4.4 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.2 2.5 GO:0034626 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.2 6.7 GO:0007398 ectoderm development(GO:0007398)
0.2 1.9 GO:1990253 cellular response to leucine starvation(GO:1990253)
0.2 0.6 GO:0090222 centrosome-templated microtubule nucleation(GO:0090222)
0.2 1.2 GO:0002826 negative regulation of T-helper 1 type immune response(GO:0002826)
0.2 0.6 GO:0030451 regulation of complement activation, alternative pathway(GO:0030451) negative regulation of complement activation, alternative pathway(GO:0045957)
0.2 1.2 GO:0045200 establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200)
0.2 2.3 GO:0060075 regulation of resting membrane potential(GO:0060075)
0.2 0.6 GO:0030186 melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187)
0.2 1.3 GO:0035879 plasma membrane lactate transport(GO:0035879)
0.2 1.5 GO:0048102 autophagic cell death(GO:0048102)
0.2 0.9 GO:0032815 negative regulation of natural killer cell activation(GO:0032815)
0.2 5.5 GO:0045063 T-helper 1 cell differentiation(GO:0045063)
0.2 0.7 GO:2000360 negative regulation of binding of sperm to zona pellucida(GO:2000360)
0.2 4.5 GO:0000183 chromatin silencing at rDNA(GO:0000183)
0.2 1.6 GO:0046087 cytidine catabolic process(GO:0006216) cytidine deamination(GO:0009972) cytidine metabolic process(GO:0046087)
0.2 2.0 GO:2000467 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028) positive regulation of glycogen (starch) synthase activity(GO:2000467)
0.2 0.5 GO:0034720 histone H3-K4 demethylation(GO:0034720)
0.2 1.6 GO:0040032 post-embryonic body morphogenesis(GO:0040032)
0.2 1.0 GO:0036135 Schwann cell migration(GO:0036135) regulation of Schwann cell migration(GO:1900147)
0.2 0.8 GO:0035617 stress granule disassembly(GO:0035617)
0.2 3.2 GO:0016540 protein autoprocessing(GO:0016540)
0.2 0.5 GO:0006423 cysteinyl-tRNA aminoacylation(GO:0006423)
0.2 4.0 GO:0033148 positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148)
0.2 1.1 GO:0051697 protein delipidation(GO:0051697)
0.2 3.9 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.2 0.9 GO:0043126 regulation of 1-phosphatidylinositol 4-kinase activity(GO:0043126) positive regulation of 1-phosphatidylinositol 4-kinase activity(GO:0043128)
0.2 1.9 GO:0002457 T cell antigen processing and presentation(GO:0002457)
0.2 0.9 GO:0090135 actin filament branching(GO:0090135)
0.2 1.4 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.2 2.3 GO:0070544 histone H3-K36 demethylation(GO:0070544)
0.1 0.3 GO:1903348 positive regulation of bicellular tight junction assembly(GO:1903348)
0.1 1.6 GO:0002084 protein depalmitoylation(GO:0002084)
0.1 0.4 GO:0051037 regulation of transcription involved in meiotic cell cycle(GO:0051037)
0.1 0.4 GO:1905051 regulation of base-excision repair(GO:1905051) positive regulation of base-excision repair(GO:1905053)
0.1 1.0 GO:0006196 AMP catabolic process(GO:0006196)
0.1 2.9 GO:0070863 positive regulation of protein exit from endoplasmic reticulum(GO:0070863)
0.1 0.7 GO:0071442 positive regulation of histone H3-K14 acetylation(GO:0071442)
0.1 0.4 GO:0042938 dipeptide transport(GO:0042938)
0.1 1.6 GO:1904847 cell chemotaxis to fibroblast growth factor(GO:0035766) endothelial cell chemotaxis to fibroblast growth factor(GO:0035768) regulation of cell chemotaxis to fibroblast growth factor(GO:1904847) regulation of endothelial cell chemotaxis to fibroblast growth factor(GO:2000544)
0.1 1.0 GO:0051684 maintenance of Golgi location(GO:0051684)
0.1 2.4 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.1 1.4 GO:1903764 regulation of potassium ion export across plasma membrane(GO:1903764)
0.1 1.8 GO:0072383 plus-end-directed vesicle transport along microtubule(GO:0072383)
0.1 1.3 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.1 2.4 GO:0007614 short-term memory(GO:0007614)
0.1 1.5 GO:0044821 meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
0.1 0.5 GO:0042823 pyridoxal phosphate biosynthetic process(GO:0042823)
0.1 4.1 GO:0007172 signal complex assembly(GO:0007172)
0.1 0.5 GO:0002678 chronic inflammatory response to non-antigenic stimulus(GO:0002545) positive regulation of chronic inflammatory response(GO:0002678) regulation of chronic inflammatory response to non-antigenic stimulus(GO:0002880)
0.1 0.8 GO:0019747 regulation of isoprenoid metabolic process(GO:0019747)
0.1 5.3 GO:0014046 dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059)
0.1 0.4 GO:0051795 positive regulation of catagen(GO:0051795)
0.1 0.6 GO:0038031 non-canonical Wnt signaling pathway via JNK cascade(GO:0038031)
0.1 1.1 GO:0097646 calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.1 4.4 GO:0060445 branching involved in salivary gland morphogenesis(GO:0060445)
0.1 1.0 GO:0051592 response to calcium ion(GO:0051592)
0.1 3.0 GO:0006349 regulation of gene expression by genetic imprinting(GO:0006349)
0.1 5.2 GO:0045104 intermediate filament cytoskeleton organization(GO:0045104)
0.1 1.3 GO:0010820 positive regulation of T cell chemotaxis(GO:0010820)
0.1 1.3 GO:0060992 response to fungicide(GO:0060992)
0.1 0.3 GO:0072365 regulation of cellular ketone metabolic process by negative regulation of transcription from RNA polymerase II promoter(GO:0072365)
0.1 2.3 GO:0070831 basement membrane assembly(GO:0070831) regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904259) positive regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904261) basement membrane assembly involved in embryonic body morphogenesis(GO:2001197)
0.1 1.6 GO:0033299 secretion of lysosomal enzymes(GO:0033299)
0.1 1.5 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
0.1 0.5 GO:0018352 protein-pyridoxal-5-phosphate linkage(GO:0018352)
0.1 1.3 GO:0046549 retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
0.1 0.2 GO:0072107 cranial ganglion development(GO:0061550) trigeminal ganglion development(GO:0061551) regulation of ureteric bud formation(GO:0072106) positive regulation of ureteric bud formation(GO:0072107)
0.1 5.3 GO:0042572 retinol metabolic process(GO:0042572)
0.1 1.2 GO:0060056 mammary gland involution(GO:0060056)
0.1 1.9 GO:0043046 DNA methylation involved in gamete generation(GO:0043046)
0.1 0.3 GO:0050882 voluntary musculoskeletal movement(GO:0050882)
0.1 0.9 GO:0006868 glutamine transport(GO:0006868) L-cystine transport(GO:0015811)
0.1 2.9 GO:0006054 N-acetylneuraminate metabolic process(GO:0006054)
0.1 1.1 GO:0045836 positive regulation of meiotic nuclear division(GO:0045836)
0.1 0.4 GO:0051902 negative regulation of mitochondrial depolarization(GO:0051902)
0.1 0.4 GO:0015670 carbon dioxide transport(GO:0015670)
0.1 3.6 GO:1902857 positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.1 0.1 GO:0035494 SNARE complex disassembly(GO:0035494)
0.1 0.6 GO:0016480 negative regulation of transcription from RNA polymerase III promoter(GO:0016480)
0.1 1.1 GO:2000664 positive regulation of interleukin-5 secretion(GO:2000664)
0.1 0.3 GO:0042636 negative regulation of hair cycle(GO:0042636)
0.1 2.1 GO:0006939 smooth muscle contraction(GO:0006939)
0.1 0.8 GO:0007296 vitellogenesis(GO:0007296)
0.1 1.7 GO:1904714 regulation of chaperone-mediated autophagy(GO:1904714)
0.1 0.6 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.1 0.7 GO:0090625 mRNA cleavage involved in gene silencing by siRNA(GO:0090625)
0.1 0.7 GO:0050689 negative regulation of defense response to virus by host(GO:0050689)
0.1 3.8 GO:0043090 amino acid import(GO:0043090)
0.1 2.0 GO:2000811 negative regulation of anoikis(GO:2000811)
0.1 0.4 GO:0030011 maintenance of cell polarity(GO:0030011) maintenance of apical/basal cell polarity(GO:0035090) maintenance of epithelial cell apical/basal polarity(GO:0045199)
0.1 0.8 GO:0035965 cardiolipin acyl-chain remodeling(GO:0035965)
0.1 1.2 GO:0015705 iodide transport(GO:0015705)
0.1 2.1 GO:0036149 phosphatidylinositol acyl-chain remodeling(GO:0036149)
0.1 0.8 GO:0050957 equilibrioception(GO:0050957)
0.1 2.2 GO:0051693 actin filament capping(GO:0051693)
0.1 1.0 GO:0050930 induction of positive chemotaxis(GO:0050930)
0.1 0.6 GO:0090206 negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.1 1.9 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.1 1.3 GO:2000786 positive regulation of autophagosome assembly(GO:2000786)
0.1 0.3 GO:0071284 cellular response to lead ion(GO:0071284)
0.1 1.1 GO:0021759 globus pallidus development(GO:0021759)
0.1 0.2 GO:0006990 positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response(GO:0006990)
0.1 1.1 GO:0009249 protein lipoylation(GO:0009249)
0.1 0.3 GO:0015825 L-serine transport(GO:0015825)
0.1 0.4 GO:0008065 establishment of blood-nerve barrier(GO:0008065)
0.1 0.8 GO:0002480 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent(GO:0002480)
0.1 1.2 GO:1904424 regulation of GTP binding(GO:1904424)
0.1 0.4 GO:0070980 biphenyl catabolic process(GO:0070980)
0.1 1.1 GO:0090336 positive regulation of brown fat cell differentiation(GO:0090336)
0.1 1.0 GO:1902570 protein localization to nucleolus(GO:1902570)
0.1 1.9 GO:0044342 type B pancreatic cell proliferation(GO:0044342)
0.1 0.9 GO:0016199 axon midline choice point recognition(GO:0016199)
0.1 0.1 GO:0046833 positive regulation of RNA export from nucleus(GO:0046833)
0.1 0.9 GO:0038003 opioid receptor signaling pathway(GO:0038003)
0.1 0.7 GO:1903715 regulation of aerobic respiration(GO:1903715)
0.1 0.6 GO:0046349 UDP-N-acetylglucosamine biosynthetic process(GO:0006048) amino sugar biosynthetic process(GO:0046349)
0.1 0.4 GO:0030573 bile acid catabolic process(GO:0030573)
0.1 0.2 GO:1903722 regulation of centriole elongation(GO:1903722)
0.1 1.1 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.1 0.9 GO:0090190 positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190)
0.1 0.6 GO:0048484 enteric nervous system development(GO:0048484)
0.1 0.5 GO:1903301 positive regulation of glucokinase activity(GO:0033133) positive regulation of hexokinase activity(GO:1903301)
0.1 0.7 GO:0051583 dopamine uptake involved in synaptic transmission(GO:0051583) catecholamine uptake involved in synaptic transmission(GO:0051934) catecholamine uptake(GO:0090493) dopamine uptake(GO:0090494)
0.1 1.4 GO:0045835 negative regulation of meiotic nuclear division(GO:0045835)
0.1 1.0 GO:0060252 positive regulation of glial cell proliferation(GO:0060252)
0.1 0.3 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.1 0.4 GO:0006311 meiotic gene conversion(GO:0006311)
0.1 19.6 GO:0043542 endothelial cell migration(GO:0043542)
0.1 0.5 GO:0032510 endosome to lysosome transport via multivesicular body sorting pathway(GO:0032510)
0.1 0.4 GO:0035162 embryonic hemopoiesis(GO:0035162)
0.1 1.2 GO:0000271 polysaccharide biosynthetic process(GO:0000271)
0.1 3.7 GO:0090004 positive regulation of establishment of protein localization to plasma membrane(GO:0090004)
0.1 0.8 GO:0097011 cellular response to granulocyte macrophage colony-stimulating factor stimulus(GO:0097011) response to granulocyte macrophage colony-stimulating factor(GO:0097012)
0.1 0.5 GO:0033313 meiotic cell cycle checkpoint(GO:0033313)
0.1 2.5 GO:0001913 T cell mediated cytotoxicity(GO:0001913)
0.1 0.4 GO:1902455 negative regulation of stem cell population maintenance(GO:1902455)
0.1 2.8 GO:0061003 positive regulation of dendritic spine morphogenesis(GO:0061003)
0.1 0.3 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
0.1 1.9 GO:0007216 G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.1 0.5 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
0.1 0.7 GO:0072189 ureter development(GO:0072189)
0.1 0.5 GO:0060154 cellular process regulating host cell cycle in response to virus(GO:0060154)
0.1 1.8 GO:0048025 negative regulation of mRNA splicing, via spliceosome(GO:0048025)
0.1 0.1 GO:0014009 glial cell proliferation(GO:0014009)
0.1 0.4 GO:0030042 actin filament depolymerization(GO:0030042)
0.1 0.3 GO:0038155 interleukin-23-mediated signaling pathway(GO:0038155)
0.1 7.2 GO:0042795 snRNA transcription(GO:0009301) snRNA transcription from RNA polymerase II promoter(GO:0042795)
0.1 1.2 GO:0030208 dermatan sulfate metabolic process(GO:0030205) dermatan sulfate biosynthetic process(GO:0030208)
0.1 0.7 GO:0036506 maintenance of unfolded protein(GO:0036506) maintenance of unfolded protein involved in ERAD pathway(GO:1904378)
0.1 0.4 GO:0051552 flavone metabolic process(GO:0051552)
0.1 1.5 GO:1902187 negative regulation of viral release from host cell(GO:1902187)
0.1 0.1 GO:0050653 chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0050653)
0.1 3.4 GO:0018149 peptide cross-linking(GO:0018149)
0.1 2.6 GO:0035428 hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659)
0.1 0.3 GO:0006438 valyl-tRNA aminoacylation(GO:0006438)
0.1 0.5 GO:0071896 protein localization to adherens junction(GO:0071896)
0.1 0.7 GO:0019919 peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919)
0.1 1.4 GO:0071985 multivesicular body sorting pathway(GO:0071985)
0.1 1.1 GO:0007342 fusion of sperm to egg plasma membrane(GO:0007342)
0.1 1.8 GO:0042753 positive regulation of circadian rhythm(GO:0042753)
0.1 0.2 GO:0060011 Sertoli cell proliferation(GO:0060011)
0.1 0.7 GO:0097267 omega-hydroxylase P450 pathway(GO:0097267)
0.1 0.4 GO:0061299 retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.1 1.7 GO:0045056 transcytosis(GO:0045056)
0.1 0.5 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.1 2.0 GO:1900027 regulation of ruffle assembly(GO:1900027)
0.1 0.5 GO:0080009 mRNA methylation(GO:0080009)
0.1 0.2 GO:0046022 positive regulation of transcription from RNA polymerase II promoter during mitosis(GO:0046022)
0.1 0.5 GO:0019896 axonal transport of mitochondrion(GO:0019896)
0.1 1.0 GO:0060712 spongiotrophoblast layer development(GO:0060712)
0.1 0.6 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.1 1.7 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.1 3.1 GO:0006376 mRNA splice site selection(GO:0006376)
0.1 0.9 GO:0060294 cilium movement involved in cell motility(GO:0060294)
0.1 0.8 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.1 7.3 GO:0090630 activation of GTPase activity(GO:0090630)
0.1 1.8 GO:0015991 ATP hydrolysis coupled proton transport(GO:0015991)
0.1 1.1 GO:0048935 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.1 0.3 GO:0061086 negative regulation of histone H3-K27 methylation(GO:0061086)
0.1 0.2 GO:0071850 mitotic cell cycle arrest(GO:0071850)
0.1 1.0 GO:0097062 dendritic spine maintenance(GO:0097062)
0.1 0.4 GO:0035234 ectopic germ cell programmed cell death(GO:0035234)
0.1 0.5 GO:0070315 G1 to G0 transition involved in cell differentiation(GO:0070315)
0.0 2.5 GO:1904837 beta-catenin-TCF complex assembly(GO:1904837)
0.0 0.2 GO:0090410 malonate catabolic process(GO:0090410)
0.0 0.6 GO:0070900 mitochondrial tRNA modification(GO:0070900) mitochondrial RNA modification(GO:1900864)
0.0 1.7 GO:0045022 early endosome to late endosome transport(GO:0045022)
0.0 3.1 GO:0050690 regulation of defense response to virus by virus(GO:0050690)
0.0 0.4 GO:0035457 cellular response to interferon-alpha(GO:0035457)
0.0 0.4 GO:1901341 activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.0 0.8 GO:0048681 negative regulation of axon regeneration(GO:0048681) negative regulation of neuron projection regeneration(GO:0070571)
0.0 0.3 GO:0006177 GMP biosynthetic process(GO:0006177)
0.0 0.3 GO:0035021 negative regulation of Rac protein signal transduction(GO:0035021)
0.0 0.5 GO:2000680 rubidium ion transport(GO:0035826) regulation of rubidium ion transport(GO:2000680)
0.0 0.0 GO:0002522 leukocyte migration involved in immune response(GO:0002522)
0.0 1.1 GO:0001829 trophectodermal cell differentiation(GO:0001829)
0.0 0.6 GO:0090023 positive regulation of neutrophil chemotaxis(GO:0090023)
0.0 0.2 GO:0033274 response to vitamin B2(GO:0033274) heterochromatin maintenance(GO:0070829)
0.0 2.8 GO:0043392 negative regulation of DNA binding(GO:0043392)
0.0 0.1 GO:0050823 peptide stabilization(GO:0050822) peptide antigen stabilization(GO:0050823)
0.0 0.9 GO:0050890 cognition(GO:0050890)
0.0 0.5 GO:0048839 inner ear development(GO:0048839)
0.0 0.7 GO:0090361 platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
0.0 2.4 GO:0006730 one-carbon metabolic process(GO:0006730)
0.0 0.9 GO:0031639 plasminogen activation(GO:0031639)
0.0 7.5 GO:0007173 epidermal growth factor receptor signaling pathway(GO:0007173)
0.0 0.6 GO:0031953 negative regulation of protein autophosphorylation(GO:0031953)
0.0 0.3 GO:0002175 protein localization to paranode region of axon(GO:0002175)
0.0 1.7 GO:0007190 activation of adenylate cyclase activity(GO:0007190)
0.0 0.7 GO:0045008 depyrimidination(GO:0045008)
0.0 1.3 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0 0.1 GO:0046340 diacylglycerol catabolic process(GO:0046340)
0.0 2.7 GO:0001895 retina homeostasis(GO:0001895)
0.0 0.3 GO:0071802 negative regulation of podosome assembly(GO:0071802)
0.0 0.5 GO:0060263 regulation of respiratory burst(GO:0060263)
0.0 0.9 GO:1903204 negative regulation of oxidative stress-induced neuron death(GO:1903204)
0.0 0.4 GO:0001553 luteinization(GO:0001553)
0.0 2.8 GO:0006027 glycosaminoglycan catabolic process(GO:0006027)
0.0 0.8 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 0.2 GO:0042078 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
0.0 0.2 GO:2000052 positive regulation of non-canonical Wnt signaling pathway(GO:2000052)
0.0 0.1 GO:1903413 cellular response to bile acid(GO:1903413)
0.0 0.1 GO:0042590 antigen processing and presentation of exogenous peptide antigen via MHC class I(GO:0042590)
0.0 1.0 GO:0016242 negative regulation of macroautophagy(GO:0016242)
0.0 0.2 GO:0042733 embryonic digit morphogenesis(GO:0042733)
0.0 3.4 GO:0006501 C-terminal protein lipidation(GO:0006501)
0.0 0.3 GO:0060677 ureteric bud elongation(GO:0060677)
0.0 2.7 GO:1902600 hydrogen ion transmembrane transport(GO:1902600)
0.0 0.5 GO:0048147 negative regulation of fibroblast proliferation(GO:0048147)
0.0 0.8 GO:0006783 heme biosynthetic process(GO:0006783)
0.0 0.4 GO:0019730 antimicrobial humoral response(GO:0019730)
0.0 0.2 GO:1903265 positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
0.0 0.1 GO:0032661 regulation of interleukin-18 production(GO:0032661)
0.0 1.4 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 0.4 GO:0015693 magnesium ion transport(GO:0015693)
0.0 0.5 GO:0043562 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 0.1 GO:0090119 vesicle-mediated cholesterol transport(GO:0090119)
0.0 0.4 GO:0050919 negative chemotaxis(GO:0050919)
0.0 0.2 GO:0097398 response to interleukin-17(GO:0097396) cellular response to interleukin-17(GO:0097398)
0.0 0.2 GO:0032233 positive regulation of actin filament bundle assembly(GO:0032233)
0.0 0.5 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0 0.2 GO:0045647 negative regulation of erythrocyte differentiation(GO:0045647)
0.0 2.3 GO:0042147 retrograde transport, endosome to Golgi(GO:0042147)
0.0 0.1 GO:0052651 monoacylglycerol metabolic process(GO:0046462) monoacylglycerol catabolic process(GO:0052651)
0.0 0.1 GO:2001184 positive regulation of interleukin-12 secretion(GO:2001184)
0.0 0.1 GO:0046548 retinal rod cell development(GO:0046548)
0.0 0.1 GO:0014028 notochord formation(GO:0014028)
0.0 0.3 GO:0001865 NK T cell differentiation(GO:0001865)
0.0 1.6 GO:0033209 tumor necrosis factor-mediated signaling pathway(GO:0033209)
0.0 0.5 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.0 0.3 GO:0060087 relaxation of vascular smooth muscle(GO:0060087)
0.0 0.2 GO:0019556 formate metabolic process(GO:0015942) histidine catabolic process to glutamate and formamide(GO:0019556) histidine catabolic process to glutamate and formate(GO:0019557) formamide metabolic process(GO:0043606)
0.0 0.6 GO:0000466 maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000466)
0.0 0.3 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
0.0 0.6 GO:0035360 positive regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035360)
0.0 0.2 GO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.0 0.7 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 0.2 GO:0090043 regulation of tubulin deacetylation(GO:0090043)
0.0 1.2 GO:0045921 positive regulation of exocytosis(GO:0045921)
0.0 0.3 GO:0015871 choline transport(GO:0015871) negative regulation of RIG-I signaling pathway(GO:0039536)
0.0 0.2 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
0.0 0.3 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.0 1.9 GO:0006901 vesicle coating(GO:0006901) vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208)
0.0 0.3 GO:0060285 cilium-dependent cell motility(GO:0060285)
0.0 0.2 GO:0090141 positive regulation of mitochondrial fission(GO:0090141)
0.0 0.2 GO:0014850 response to muscle activity(GO:0014850)
0.0 1.8 GO:0097031 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 0.1 GO:2001287 negative regulation of caveolin-mediated endocytosis(GO:2001287)
0.0 1.0 GO:1904893 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0 0.0 GO:0042986 positive regulation of amyloid precursor protein biosynthetic process(GO:0042986)
0.0 0.2 GO:0015860 purine nucleoside transmembrane transport(GO:0015860)
0.0 0.1 GO:0051490 negative regulation of filopodium assembly(GO:0051490)
0.0 0.9 GO:0000380 alternative mRNA splicing, via spliceosome(GO:0000380)
0.0 0.1 GO:2000312 regulation of kainate selective glutamate receptor activity(GO:2000312)
0.0 0.2 GO:0071763 nuclear membrane organization(GO:0071763)
0.0 0.1 GO:0051918 regulation of fibrinolysis(GO:0051917) negative regulation of fibrinolysis(GO:0051918)
0.0 0.3 GO:0035067 negative regulation of histone acetylation(GO:0035067)
0.0 0.6 GO:0035456 response to interferon-beta(GO:0035456)
0.0 0.2 GO:0045773 positive regulation of axon extension(GO:0045773)
0.0 0.9 GO:0090398 cellular senescence(GO:0090398)
0.0 0.1 GO:0033383 geranyl diphosphate metabolic process(GO:0033383) geranyl diphosphate biosynthetic process(GO:0033384) farnesyl diphosphate biosynthetic process(GO:0045337)
0.0 0.3 GO:0006516 glycoprotein catabolic process(GO:0006516)
0.0 0.4 GO:0036109 alpha-linolenic acid metabolic process(GO:0036109)
0.0 0.5 GO:0070286 axonemal dynein complex assembly(GO:0070286)
0.0 1.5 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.0 0.6 GO:0018345 protein palmitoylation(GO:0018345)
0.0 0.1 GO:0019626 short-chain fatty acid catabolic process(GO:0019626)
0.0 0.1 GO:0001955 blood vessel maturation(GO:0001955)
0.0 0.2 GO:0060180 female mating behavior(GO:0060180)
0.0 0.4 GO:0034243 regulation of transcription elongation from RNA polymerase II promoter(GO:0034243)
0.0 0.8 GO:0006968 cellular defense response(GO:0006968)
0.0 0.4 GO:0032011 ARF protein signal transduction(GO:0032011)
0.0 0.7 GO:0045576 mast cell activation(GO:0045576)
0.0 0.3 GO:0051904 melanosome transport(GO:0032402) pigment granule transport(GO:0051904)
0.0 0.2 GO:0006878 cellular copper ion homeostasis(GO:0006878)
0.0 0.2 GO:1904871 regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871)
0.0 0.1 GO:0050435 beta-amyloid metabolic process(GO:0050435)
0.0 0.9 GO:0051972 regulation of telomerase activity(GO:0051972)
0.0 0.6 GO:0006910 phagocytosis, recognition(GO:0006910)
0.0 0.1 GO:0008356 asymmetric cell division(GO:0008356)
0.0 0.1 GO:0008298 intracellular mRNA localization(GO:0008298)
0.0 0.7 GO:0006368 transcription elongation from RNA polymerase II promoter(GO:0006368)
0.0 0.3 GO:0046320 regulation of fatty acid oxidation(GO:0046320)
0.0 0.3 GO:0060325 face morphogenesis(GO:0060325)
0.0 0.7 GO:0070206 protein trimerization(GO:0070206)
0.0 0.2 GO:0071800 podosome assembly(GO:0071800)
0.0 1.9 GO:1902476 chloride transmembrane transport(GO:1902476)
0.0 0.1 GO:0097194 execution phase of apoptosis(GO:0097194)
0.0 0.1 GO:1901203 positive regulation of extracellular matrix assembly(GO:1901203)
0.0 0.1 GO:1903597 negative regulation of gap junction assembly(GO:1903597)
0.0 0.4 GO:0051602 response to electrical stimulus(GO:0051602)
0.0 0.1 GO:0006552 leucine catabolic process(GO:0006552)
0.0 0.1 GO:0045475 locomotor rhythm(GO:0045475)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
2.2 15.1 GO:0097209 epidermal lamellar body(GO:0097209)
2.1 8.4 GO:0005607 laminin-2 complex(GO:0005607)
1.9 7.7 GO:0071665 gamma-catenin-TCF7L2 complex(GO:0071665)
1.9 1.9 GO:0071062 alphav-beta3 integrin-vitronectin complex(GO:0071062)
1.2 13.4 GO:0005610 laminin-5 complex(GO:0005610)
1.1 3.4 GO:0043512 inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.9 2.6 GO:1990032 parallel fiber(GO:1990032)
0.6 4.5 GO:0033553 rDNA heterochromatin(GO:0033553)
0.6 3.0 GO:0060053 neurofilament cytoskeleton(GO:0060053)
0.5 3.8 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
0.5 2.8 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
0.4 1.1 GO:0000229 cytoplasmic chromosome(GO:0000229)
0.3 6.2 GO:0097512 cardiac myofibril(GO:0097512)
0.3 2.2 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.3 8.1 GO:0005922 connexon complex(GO:0005922)
0.3 4.1 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.3 1.8 GO:1990131 Gtr1-Gtr2 GTPase complex(GO:1990131)
0.3 4.0 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.3 0.9 GO:0030895 apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.3 1.3 GO:0031528 microvillus membrane(GO:0031528)
0.3 22.5 GO:0045095 keratin filament(GO:0045095)
0.3 1.5 GO:0005958 DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958)
0.2 9.7 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.2 4.8 GO:0042613 MHC class II protein complex(GO:0042613)
0.2 0.7 GO:0032783 ELL-EAF complex(GO:0032783)
0.2 1.3 GO:0097513 myosin II filament(GO:0097513)
0.2 0.7 GO:0035189 Rb-E2F complex(GO:0035189)
0.2 3.7 GO:0016600 flotillin complex(GO:0016600)
0.2 0.9 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
0.2 1.6 GO:0070695 FHF complex(GO:0070695)
0.2 2.4 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.2 1.8 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.2 1.6 GO:0070847 core mediator complex(GO:0070847)
0.2 3.3 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.2 1.5 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.2 0.6 GO:0000502 proteasome complex(GO:0000502)
0.2 1.1 GO:1903440 calcitonin family receptor complex(GO:1903439) amylin receptor complex(GO:1903440)
0.2 0.9 GO:0001405 presequence translocase-associated import motor(GO:0001405)
0.2 0.9 GO:0030906 retromer, cargo-selective complex(GO:0030906)
0.2 1.0 GO:0071546 pi-body(GO:0071546)
0.2 0.9 GO:0000333 telomerase catalytic core complex(GO:0000333)
0.2 0.5 GO:0034515 proteasome storage granule(GO:0034515)
0.2 0.3 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.2 3.9 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.2 2.6 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.2 0.8 GO:0071547 piP-body(GO:0071547)
0.2 0.5 GO:0097441 basilar dendrite(GO:0097441)
0.2 11.2 GO:0001533 cornified envelope(GO:0001533)
0.2 2.2 GO:0000322 storage vacuole(GO:0000322)
0.2 4.9 GO:0005614 interstitial matrix(GO:0005614)
0.2 1.1 GO:0035061 interchromatin granule(GO:0035061)
0.2 0.6 GO:0036449 microtubule minus-end(GO:0036449)
0.2 0.9 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.1 2.8 GO:0008290 F-actin capping protein complex(GO:0008290)
0.1 4.5 GO:0001891 phagocytic cup(GO:0001891)
0.1 2.4 GO:0098574 cytoplasmic side of lysosomal membrane(GO:0098574)
0.1 1.1 GO:0070876 SOSS complex(GO:0070876)
0.1 0.8 GO:0020016 ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018)
0.1 7.4 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.1 2.3 GO:0045180 basal cortex(GO:0045180)
0.1 0.5 GO:0036396 MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
0.1 1.0 GO:0070852 cell body fiber(GO:0070852)
0.1 1.5 GO:0002116 semaphorin receptor complex(GO:0002116)
0.1 0.4 GO:0035686 sperm fibrous sheath(GO:0035686)
0.1 0.8 GO:0061617 MICOS complex(GO:0061617)
0.1 1.2 GO:0061689 tricellular tight junction(GO:0061689)
0.1 0.7 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.1 2.2 GO:0034362 low-density lipoprotein particle(GO:0034362)
0.1 1.0 GO:0005955 calcineurin complex(GO:0005955)
0.1 1.6 GO:0070578 RISC-loading complex(GO:0070578)
0.1 2.8 GO:0035145 exon-exon junction complex(GO:0035145)
0.1 2.8 GO:0071141 SMAD protein complex(GO:0071141)
0.1 0.3 GO:0045281 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.1 10.2 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.1 0.9 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.1 1.1 GO:0031088 platelet dense granule membrane(GO:0031088)
0.1 1.5 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.1 2.1 GO:0030056 hemidesmosome(GO:0030056)
0.1 2.1 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.1 0.4 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
0.1 4.2 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.1 0.8 GO:0042611 MHC protein complex(GO:0042611)
0.1 1.7 GO:0097225 sperm midpiece(GO:0097225)
0.1 1.1 GO:0045179 apical cortex(GO:0045179)
0.1 0.4 GO:0033647 host intracellular organelle(GO:0033647) host intracellular membrane-bounded organelle(GO:0033648)
0.1 4.9 GO:0008023 transcription elongation factor complex(GO:0008023)
0.1 0.9 GO:0036157 outer dynein arm(GO:0036157)
0.1 9.0 GO:0005604 basement membrane(GO:0005604)
0.1 2.5 GO:0097228 sperm principal piece(GO:0097228)
0.1 0.3 GO:0097454 Schwann cell microvillus(GO:0097454)
0.1 1.8 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.1 0.3 GO:0072536 interleukin-23 receptor complex(GO:0072536)
0.1 3.9 GO:0008180 COP9 signalosome(GO:0008180)
0.1 10.6 GO:0017053 transcriptional repressor complex(GO:0017053)
0.1 0.5 GO:0043020 NADPH oxidase complex(GO:0043020)
0.1 0.3 GO:0016938 kinesin I complex(GO:0016938)
0.1 2.8 GO:0032587 ruffle membrane(GO:0032587)
0.1 1.7 GO:0031305 intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305)
0.1 2.3 GO:0031105 septin complex(GO:0031105)
0.1 7.3 GO:0005811 lipid particle(GO:0005811)
0.1 9.3 GO:0005913 cell-cell adherens junction(GO:0005913)
0.1 0.7 GO:0071818 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.1 5.3 GO:0030134 ER to Golgi transport vesicle(GO:0030134)
0.1 2.0 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.1 0.6 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.1 1.6 GO:0005639 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.1 0.6 GO:0005694 chromosome(GO:0005694)
0.1 2.7 GO:0001772 immunological synapse(GO:0001772)
0.1 2.2 GO:0000421 autophagosome membrane(GO:0000421)
0.0 0.1 GO:0035841 new growing cell tip(GO:0035841)
0.0 0.5 GO:0033263 CORVET complex(GO:0033263)
0.0 8.0 GO:0016605 PML body(GO:0016605)
0.0 0.6 GO:0001940 male pronucleus(GO:0001940)
0.0 4.5 GO:1904724 tertiary granule lumen(GO:1904724)
0.0 0.7 GO:0044754 autolysosome(GO:0044754)
0.0 4.9 GO:0034707 chloride channel complex(GO:0034707)
0.0 0.3 GO:0030673 axolemma(GO:0030673)
0.0 2.1 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 1.1 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.4 GO:0016234 inclusion body(GO:0016234)
0.0 1.2 GO:0031045 dense core granule(GO:0031045)
0.0 0.2 GO:1990876 cytoplasmic side of nuclear pore(GO:1990876)
0.0 1.6 GO:0071339 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0 0.5 GO:0033391 chromatoid body(GO:0033391)
0.0 1.2 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.0 0.2 GO:0097255 R2TP complex(GO:0097255)
0.0 0.5 GO:0030681 multimeric ribonuclease P complex(GO:0030681)
0.0 2.6 GO:0005801 cis-Golgi network(GO:0005801)
0.0 1.5 GO:0043034 costamere(GO:0043034)
0.0 1.2 GO:0071437 invadopodium(GO:0071437)
0.0 0.3 GO:0097470 ribbon synapse(GO:0097470)
0.0 0.7 GO:0005861 troponin complex(GO:0005861)
0.0 0.5 GO:0061202 clathrin-sculpted gamma-aminobutyric acid transport vesicle(GO:0061200) clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane(GO:0061202)
0.0 0.5 GO:0032039 integrator complex(GO:0032039)
0.0 0.6 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 0.4 GO:0030061 mitochondrial crista(GO:0030061)
0.0 0.1 GO:0070931 Golgi-associated vesicle lumen(GO:0070931)
0.0 5.1 GO:0031225 anchored component of membrane(GO:0031225)
0.0 1.9 GO:0043296 apical junction complex(GO:0043296)
0.0 0.2 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 1.9 GO:0030666 endocytic vesicle membrane(GO:0030666)
0.0 1.9 GO:0005637 nuclear inner membrane(GO:0005637)
0.0 0.3 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 3.3 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 1.0 GO:0031258 lamellipodium membrane(GO:0031258)
0.0 0.5 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.3 GO:0005858 axonemal dynein complex(GO:0005858)
0.0 1.6 GO:0002102 podosome(GO:0002102)
0.0 2.4 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 3.2 GO:0016528 sarcoplasm(GO:0016528)
0.0 0.2 GO:0000138 Golgi trans cisterna(GO:0000138)
0.0 0.6 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 0.5 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 0.1 GO:0051233 spindle midzone(GO:0051233)
0.0 1.2 GO:0045178 basal part of cell(GO:0045178)
0.0 3.3 GO:0016363 nuclear matrix(GO:0016363)
0.0 2.4 GO:0097517 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 0.2 GO:0097169 AIM2 inflammasome complex(GO:0097169)
0.0 0.9 GO:0031941 filamentous actin(GO:0031941)
0.0 0.6 GO:0101003 ficolin-1-rich granule membrane(GO:0101003)
0.0 1.1 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.6 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 3.6 GO:0031901 early endosome membrane(GO:0031901)
0.0 0.5 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 13.8 GO:0043025 neuronal cell body(GO:0043025)
0.0 3.3 GO:0045177 apical part of cell(GO:0045177)
0.0 0.7 GO:0005779 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.0 0.5 GO:0034451 centriolar satellite(GO:0034451)
0.0 0.9 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)
0.0 0.5 GO:0002080 acrosomal membrane(GO:0002080)
0.0 1.4 GO:0015030 Cajal body(GO:0015030)
0.0 1.0 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 0.1 GO:0001917 photoreceptor inner segment(GO:0001917)
0.0 1.3 GO:0005776 autophagosome(GO:0005776)
0.0 0.3 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.2 GO:0072546 ER membrane protein complex(GO:0072546)
0.0 0.3 GO:0033270 paranode region of axon(GO:0033270)
0.0 0.1 GO:0071556 integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553)
0.0 0.1 GO:1905202 3-methylcrotonyl-CoA carboxylase complex, mitochondrial(GO:0002169) methylcrotonoyl-CoA carboxylase complex(GO:1905202)
0.0 1.3 GO:0001669 acrosomal vesicle(GO:0001669)
0.0 1.0 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 1.2 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 0.1 GO:1902912 pyruvate kinase complex(GO:1902912)
0.0 1.4 GO:0035579 specific granule membrane(GO:0035579)
0.0 0.1 GO:0016589 NURF complex(GO:0016589)
0.0 0.6 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 0.1 GO:0098839 postsynaptic density membrane(GO:0098839)
0.0 1.3 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 0.9 GO:0042734 presynaptic membrane(GO:0042734)
0.0 1.4 GO:0030136 clathrin-coated vesicle(GO:0030136)
0.0 1.0 GO:0035578 azurophil granule lumen(GO:0035578)
0.0 0.2 GO:0002199 zona pellucida receptor complex(GO:0002199)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.9 7.7 GO:0005199 structural constituent of cell wall(GO:0005199)
1.8 9.1 GO:0030197 extracellular matrix constituent, lubricant activity(GO:0030197)
1.7 8.4 GO:0060961 phospholipase D inhibitor activity(GO:0060961)
1.2 7.3 GO:0019828 aspartic-type endopeptidase inhibitor activity(GO:0019828)
1.1 5.3 GO:0050253 retinyl-palmitate esterase activity(GO:0050253)
1.0 7.0 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
1.0 2.9 GO:0098770 FBXO family protein binding(GO:0098770)
0.9 2.7 GO:0070538 oleic acid binding(GO:0070538)
0.7 3.0 GO:0070012 oligopeptidase activity(GO:0070012)
0.7 2.9 GO:0004913 interleukin-4 receptor activity(GO:0004913)
0.7 2.0 GO:0036487 nitric-oxide synthase inhibitor activity(GO:0036487)
0.6 1.9 GO:1902271 D3 vitamins binding(GO:1902271)
0.6 1.9 GO:0061663 NEDD8 ligase activity(GO:0061663)
0.6 3.4 GO:0070699 type II activin receptor binding(GO:0070699)
0.6 1.7 GO:0004174 electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
0.5 2.2 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.5 11.6 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.5 1.6 GO:0019150 D-ribulokinase activity(GO:0019150)
0.5 4.5 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.5 1.5 GO:0015218 pyrimidine nucleotide transmembrane transporter activity(GO:0015218)
0.4 1.3 GO:0016964 alpha-2 macroglobulin receptor activity(GO:0016964)
0.4 5.8 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.4 5.7 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.4 1.1 GO:0004961 thromboxane receptor activity(GO:0004960) thromboxane A2 receptor activity(GO:0004961)
0.4 1.1 GO:0002113 interleukin-33 binding(GO:0002113)
0.3 2.8 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.3 4.8 GO:0032395 MHC class II receptor activity(GO:0032395)
0.3 1.3 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.3 8.3 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.3 0.9 GO:0004807 triose-phosphate isomerase activity(GO:0004807)
0.3 0.9 GO:0017130 poly(C) RNA binding(GO:0017130)
0.3 2.7 GO:0035500 MH2 domain binding(GO:0035500)
0.3 2.4 GO:0042289 MHC class II protein binding(GO:0042289)
0.3 2.9 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.3 0.9 GO:0032093 SAM domain binding(GO:0032093)
0.3 3.4 GO:0030280 structural constituent of epidermis(GO:0030280)
0.3 1.1 GO:0031716 calcitonin receptor activity(GO:0004948) calcitonin receptor binding(GO:0031716)
0.3 1.4 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.3 1.4 GO:0004556 alpha-amylase activity(GO:0004556)
0.3 1.0 GO:0050698 proteoglycan sulfotransferase activity(GO:0050698)
0.3 1.5 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.3 1.5 GO:0080019 fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019)
0.3 3.3 GO:0046703 natural killer cell lectin-like receptor binding(GO:0046703)
0.3 1.3 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.2 1.5 GO:0045174 oxidoreductase activity, acting on a sulfur group of donors, quinone or similar compound as acceptor(GO:0016672) glutathione dehydrogenase (ascorbate) activity(GO:0045174) methylarsonate reductase activity(GO:0050610)
0.2 4.4 GO:0015250 water channel activity(GO:0015250)
0.2 1.0 GO:0033823 procollagen-lysine 5-dioxygenase activity(GO:0008475) procollagen glucosyltransferase activity(GO:0033823)
0.2 1.9 GO:0004771 sterol esterase activity(GO:0004771)
0.2 0.9 GO:0032427 GBD domain binding(GO:0032427)
0.2 0.9 GO:0047751 3-oxo-5-alpha-steroid 4-dehydrogenase activity(GO:0003865) steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765) cholestenone 5-alpha-reductase activity(GO:0047751)
0.2 2.4 GO:0043533 inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.2 2.4 GO:0003847 1-alkyl-2-acetylglycerophosphocholine esterase activity(GO:0003847)
0.2 2.8 GO:0009881 photoreceptor activity(GO:0009881)
0.2 5.0 GO:0005212 structural constituent of eye lens(GO:0005212)
0.2 6.2 GO:0038191 neuropilin binding(GO:0038191)
0.2 0.6 GO:0004877 complement component C4b receptor activity(GO:0001861) complement component C3b receptor activity(GO:0004877)
0.2 3.7 GO:0032036 myosin heavy chain binding(GO:0032036)
0.2 4.3 GO:0051400 BH domain binding(GO:0051400)
0.2 0.9 GO:0019144 ADP-sugar diphosphatase activity(GO:0019144)
0.2 1.5 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.2 3.2 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.2 1.9 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.2 0.9 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.2 3.4 GO:0005243 gap junction channel activity(GO:0005243)
0.2 0.5 GO:0004817 cysteine-tRNA ligase activity(GO:0004817)
0.2 3.9 GO:0001163 RNA polymerase I regulatory region DNA binding(GO:0001013) RNA polymerase I regulatory region sequence-specific DNA binding(GO:0001163) RNA polymerase I CORE element sequence-specific DNA binding(GO:0001164)
0.2 0.7 GO:0030899 calcium-dependent ATPase activity(GO:0030899)
0.2 3.9 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.2 0.6 GO:0005334 norepinephrine:sodium symporter activity(GO:0005334)
0.2 3.4 GO:0030215 semaphorin receptor binding(GO:0030215)
0.2 0.5 GO:0016422 mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity(GO:0016422)
0.1 0.4 GO:0019961 interferon binding(GO:0019961)
0.1 0.7 GO:0000702 oxidized base lesion DNA N-glycosylase activity(GO:0000702)
0.1 1.0 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.1 2.5 GO:0015194 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.1 0.4 GO:0016401 palmitoyl-CoA oxidase activity(GO:0016401)
0.1 2.3 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.1 2.2 GO:1990459 transferrin receptor binding(GO:1990459)
0.1 1.6 GO:0038132 neuregulin binding(GO:0038132)
0.1 2.1 GO:0008199 ferric iron binding(GO:0008199)
0.1 2.2 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.1 0.6 GO:0047844 deoxycytidine deaminase activity(GO:0047844)
0.1 2.3 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.1 3.1 GO:0045295 gamma-catenin binding(GO:0045295)
0.1 0.3 GO:0008177 succinate dehydrogenase (ubiquinone) activity(GO:0008177)
0.1 1.6 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.1 1.6 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.1 1.3 GO:0045159 myosin II binding(GO:0045159)
0.1 3.1 GO:0033130 acetylcholine receptor binding(GO:0033130)
0.1 1.0 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.1 0.9 GO:0015111 iodide transmembrane transporter activity(GO:0015111)
0.1 0.9 GO:0050815 phosphoserine binding(GO:0050815)
0.1 2.3 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.1 3.6 GO:0031489 myosin V binding(GO:0031489)
0.1 0.5 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.1 1.6 GO:0051430 corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.1 1.4 GO:0097016 L27 domain binding(GO:0097016)
0.1 1.3 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.1 0.5 GO:0050509 N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity(GO:0050509)
0.1 15.9 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.1 0.5 GO:0016428 tRNA (cytosine-5-)-methyltransferase activity(GO:0016428)
0.1 3.5 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.1 1.1 GO:0102336 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.1 1.0 GO:0008097 5S rRNA binding(GO:0008097)
0.1 1.3 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.1 11.8 GO:0002039 p53 binding(GO:0002039)
0.1 1.8 GO:0005537 mannose binding(GO:0005537)
0.1 0.9 GO:0004985 opioid receptor activity(GO:0004985)
0.1 0.3 GO:1904854 proteasome core complex binding(GO:1904854)
0.1 1.1 GO:0003910 DNA ligase (ATP) activity(GO:0003910)
0.1 2.2 GO:0032183 SUMO binding(GO:0032183)
0.1 3.1 GO:0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor(GO:0016646)
0.1 0.4 GO:0015563 uptake transmembrane transporter activity(GO:0015563)
0.1 1.9 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.1 1.2 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.1 0.9 GO:0015288 porin activity(GO:0015288)
0.1 2.0 GO:0019789 SUMO transferase activity(GO:0019789)
0.1 2.7 GO:0015002 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.1 0.6 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.1 21.1 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.1 3.8 GO:0004364 glutathione transferase activity(GO:0004364)
0.1 1.6 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.1 0.7 GO:0004558 alpha-1,4-glucosidase activity(GO:0004558) maltose alpha-glucosidase activity(GO:0032450)
0.1 0.5 GO:0004331 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.1 2.4 GO:0015464 acetylcholine receptor activity(GO:0015464)
0.1 0.2 GO:0004019 adenylosuccinate synthase activity(GO:0004019)
0.1 0.5 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.1 10.5 GO:0008013 beta-catenin binding(GO:0008013)
0.1 2.0 GO:0005328 neurotransmitter:sodium symporter activity(GO:0005328)
0.1 3.4 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.1 1.1 GO:0004000 adenosine deaminase activity(GO:0004000)
0.1 1.5 GO:0048185 activin binding(GO:0048185)
0.1 3.7 GO:0071889 14-3-3 protein binding(GO:0071889)
0.1 1.3 GO:0042809 vitamin D receptor binding(GO:0042809)
0.1 1.6 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.1 16.1 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.1 0.6 GO:0001016 RNA polymerase III regulatory region DNA binding(GO:0001016)
0.1 0.4 GO:0004832 valine-tRNA ligase activity(GO:0004832)
0.1 6.9 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.1 3.1 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.1 0.3 GO:0042019 interleukin-23 binding(GO:0042019) interleukin-23 receptor activity(GO:0042020)
0.1 1.8 GO:0044548 S100 protein binding(GO:0044548)
0.1 0.8 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.1 2.7 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 0.3 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.1 0.3 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.1 0.1 GO:0047238 glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.1 0.6 GO:0008172 S-methyltransferase activity(GO:0008172)
0.1 0.6 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.1 0.8 GO:0005168 neurotrophin TRKA receptor binding(GO:0005168)
0.1 3.2 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)
0.1 0.6 GO:0016618 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.1 0.2 GO:0050254 rhodopsin kinase activity(GO:0050254)
0.1 0.9 GO:0045503 dynein light chain binding(GO:0045503)
0.1 1.2 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.1 0.7 GO:0035242 protein-arginine omega-N asymmetric methyltransferase activity(GO:0035242)
0.1 1.3 GO:0008432 JUN kinase binding(GO:0008432)
0.1 2.7 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.1 0.3 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.1 1.3 GO:0050786 RAGE receptor binding(GO:0050786)
0.1 0.8 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.1 3.2 GO:0005227 calcium activated cation channel activity(GO:0005227)
0.1 0.5 GO:0008327 methyl-CpG binding(GO:0008327)
0.1 2.2 GO:0005158 insulin receptor binding(GO:0005158)
0.1 1.1 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.1 1.0 GO:0016814 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines(GO:0016814)
0.1 0.3 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.1 0.9 GO:0070411 I-SMAD binding(GO:0070411)
0.1 1.8 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.1 1.3 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.1 0.3 GO:0039552 RIG-I binding(GO:0039552)
0.1 0.9 GO:0017151 DEAD/H-box RNA helicase binding(GO:0017151)
0.1 0.5 GO:0032453 histone demethylase activity (H3-K4 specific)(GO:0032453)
0.1 0.5 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.1 3.1 GO:0036002 pre-mRNA binding(GO:0036002)
0.1 0.2 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.1 4.6 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.1 0.6 GO:0030957 Tat protein binding(GO:0030957)
0.1 1.9 GO:0005521 lamin binding(GO:0005521)
0.1 0.4 GO:0008142 oxysterol binding(GO:0008142)
0.1 0.8 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.1 1.0 GO:0015245 fatty acid transporter activity(GO:0015245)
0.0 0.1 GO:0033878 hormone-sensitive lipase activity(GO:0033878)
0.0 0.2 GO:0090409 malonyl-CoA synthetase activity(GO:0090409)
0.0 0.6 GO:1990226 histone methyltransferase binding(GO:1990226)
0.0 0.8 GO:0008970 phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
0.0 0.2 GO:0047977 linoleate 13S-lipoxygenase activity(GO:0016165) hepoxilin-epoxide hydrolase activity(GO:0047977)
0.0 0.6 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 6.6 GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds(GO:0004553)
0.0 0.2 GO:0042806 fucose binding(GO:0042806)
0.0 0.2 GO:0004382 guanosine-diphosphatase activity(GO:0004382)
0.0 1.1 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.0 1.0 GO:0042609 CD4 receptor binding(GO:0042609)
0.0 0.9 GO:0001222 transcription corepressor binding(GO:0001222)
0.0 1.5 GO:0070300 phosphatidic acid binding(GO:0070300)
0.0 0.4 GO:0004630 phospholipase D activity(GO:0004630)
0.0 0.2 GO:0060175 brain-derived neurotrophic factor-activated receptor activity(GO:0060175)
0.0 0.2 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.0 0.8 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 0.6 GO:0070569 uridylyltransferase activity(GO:0070569)
0.0 0.5 GO:0019957 C-C chemokine binding(GO:0019957)
0.0 1.0 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.0 0.1 GO:1903135 cupric ion binding(GO:1903135)
0.0 3.0 GO:0030674 protein binding, bridging(GO:0030674)
0.0 1.4 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.0 0.5 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.0 0.4 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 0.7 GO:0070008 serine-type carboxypeptidase activity(GO:0004185) serine-type exopeptidase activity(GO:0070008)
0.0 0.2 GO:0004966 galanin receptor activity(GO:0004966)
0.0 0.7 GO:0035198 miRNA binding(GO:0035198)
0.0 0.3 GO:0005497 androgen binding(GO:0005497)
0.0 0.3 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.0 0.2 GO:0005415 nucleoside:sodium symporter activity(GO:0005415)
0.0 0.3 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.0 0.1 GO:0034046 poly(G) binding(GO:0034046)
0.0 0.4 GO:0000146 microfilament motor activity(GO:0000146)
0.0 0.5 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.0 2.8 GO:0001618 virus receptor activity(GO:0001618)
0.0 1.4 GO:0001221 transcription cofactor binding(GO:0001221)
0.0 0.6 GO:0005527 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 1.1 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.0 1.8 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.6 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 0.2 GO:0005353 fructose transmembrane transporter activity(GO:0005353)
0.0 1.2 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 22.0 GO:0005198 structural molecule activity(GO:0005198)
0.0 0.8 GO:0042605 peptide antigen binding(GO:0042605)
0.0 0.3 GO:0031434 mitogen-activated protein kinase kinase binding(GO:0031434)
0.0 0.8 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 0.7 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 1.1 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.2 GO:0050692 DBD domain binding(GO:0050692)
0.0 2.7 GO:0001190 transcriptional activator activity, RNA polymerase II transcription factor binding(GO:0001190) transcriptional repressor activity, RNA polymerase II activating transcription factor binding(GO:0098811)
0.0 0.0 GO:0098847 sequence-specific single stranded DNA binding(GO:0098847)
0.0 2.0 GO:0031491 nucleosome binding(GO:0031491)
0.0 1.8 GO:0000049 tRNA binding(GO:0000049)
0.0 0.5 GO:0004526 ribonuclease P activity(GO:0004526)
0.0 0.6 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.1 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
0.0 0.1 GO:0016005 phospholipase A2 activator activity(GO:0016005)
0.0 0.2 GO:0043531 ADP binding(GO:0043531)
0.0 0.1 GO:0008798 beta-aspartyl-peptidase activity(GO:0008798)
0.0 0.2 GO:0005132 type I interferon receptor binding(GO:0005132)
0.0 0.1 GO:0047066 phospholipid-hydroperoxide glutathione peroxidase activity(GO:0047066)
0.0 5.2 GO:0051015 actin filament binding(GO:0051015)
0.0 0.3 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.0 0.8 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.7 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.0 0.2 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.0 3.2 GO:0008565 protein transporter activity(GO:0008565)
0.0 0.2 GO:0047493 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.0 0.1 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.0 0.4 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.6 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.3 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0 1.2 GO:0044325 ion channel binding(GO:0044325)
0.0 0.6 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 0.1 GO:0005344 oxygen transporter activity(GO:0005344)
0.0 0.1 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.0 0.6 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 1.7 GO:0015078 hydrogen ion transmembrane transporter activity(GO:0015078)
0.0 1.0 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.0 0.1 GO:0099580 ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.0 0.4 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.6 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 0.6 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 1.3 GO:0048365 Rac GTPase binding(GO:0048365)
0.0 1.5 GO:0004004 ATP-dependent RNA helicase activity(GO:0004004)
0.0 1.9 GO:0035591 signaling adaptor activity(GO:0035591)
0.0 0.8 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 0.1 GO:0004485 methylcrotonoyl-CoA carboxylase activity(GO:0004485)
0.0 0.9 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.1 GO:0004161 dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
0.0 0.3 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.0 0.7 GO:0050681 androgen receptor binding(GO:0050681)
0.0 1.0 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.1 GO:0043237 laminin-1 binding(GO:0043237)
0.0 0.4 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0 0.4 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.9 GO:0042162 telomeric DNA binding(GO:0042162)
0.0 3.3 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 3.3 GO:0008022 protein C-terminus binding(GO:0008022)
0.0 0.2 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.1 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.0 1.7 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.0 GO:0034736 sterol O-acyltransferase activity(GO:0004772) cholesterol O-acyltransferase activity(GO:0034736)
0.0 0.3 GO:0019843 rRNA binding(GO:0019843)
0.0 0.1 GO:0016421 CoA carboxylase activity(GO:0016421)
0.0 0.3 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 0.2 GO:0010181 FMN binding(GO:0010181)
0.0 1.0 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 23.5 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.2 4.9 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.2 1.6 SIG PIP3 SIGNALING IN CARDIAC MYOCTES Genes related to PIP3 signaling in cardiac myocytes
0.2 22.1 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.2 12.5 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.2 11.9 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.2 13.0 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.2 3.5 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.2 1.9 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.2 9.1 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.1 5.7 PID NECTIN PATHWAY Nectin adhesion pathway
0.1 1.2 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.1 8.8 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.1 5.3 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.1 8.6 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.1 2.6 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.1 1.9 SIG IL4RECEPTOR IN B LYPHOCYTES Genes related to IL4 rceptor signaling in B lymphocytes
0.1 1.2 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.1 4.9 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.1 0.3 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling
0.1 18.9 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.1 1.5 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.1 1.6 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.1 0.6 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.1 1.3 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.1 3.9 PID PI3KCI PATHWAY Class I PI3K signaling events
0.1 2.5 PID ALK1 PATHWAY ALK1 signaling events
0.1 1.2 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.1 3.3 PID TXA2PATHWAY Thromboxane A2 receptor signaling
0.0 0.4 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.0 6.5 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 1.8 PID RAS PATHWAY Regulation of Ras family activation
0.0 4.0 ST FAS SIGNALING PATHWAY Fas Signaling Pathway
0.0 8.0 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.0 0.2 PID IL23 PATHWAY IL23-mediated signaling events
0.0 0.7 PID ERBB4 PATHWAY ErbB4 signaling events
0.0 0.4 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 0.7 ST INTEGRIN SIGNALING PATHWAY Integrin Signaling Pathway
0.0 0.9 PID ER NONGENOMIC PATHWAY Plasma membrane estrogen receptor signaling
0.0 1.9 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.0 1.8 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.0 1.5 PID SHP2 PATHWAY SHP2 signaling
0.0 0.8 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 1.7 PID BMP PATHWAY BMP receptor signaling
0.0 1.3 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 7.9 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 1.5 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.0 0.6 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.2 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 0.7 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 0.7 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 0.2 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.0 0.9 PID PTP1B PATHWAY Signaling events mediated by PTP1B
0.0 1.1 PID RHOA PATHWAY RhoA signaling pathway
0.0 0.5 PID MYC PATHWAY C-MYC pathway
0.0 0.4 PID CONE PATHWAY Visual signal transduction: Cones
0.0 0.6 SIG CHEMOTAXIS Genes related to chemotaxis
0.0 0.2 ST DIFFERENTIATION PATHWAY IN PC12 CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0 0.3 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 8.9 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.5 0.5 REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS Genes involved in Nucleotide-like (purinergic) receptors
0.4 24.4 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.4 6.8 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.3 3.4 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.3 8.1 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.3 1.7 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.3 11.3 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.2 25.0 REACTOME CELL JUNCTION ORGANIZATION Genes involved in Cell junction organization
0.2 7.9 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.2 0.9 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.2 3.5 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.2 1.5 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.2 1.5 REACTOME INTEGRATION OF PROVIRUS Genes involved in Integration of provirus
0.1 4.3 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.1 0.9 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.1 1.1 REACTOME RAF MAP KINASE CASCADE Genes involved in RAF/MAP kinase cascade
0.1 2.2 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.1 3.7 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1 3.3 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.1 5.4 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.1 1.1 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.1 7.5 REACTOME SIGNAL TRANSDUCTION BY L1 Genes involved in Signal transduction by L1
0.1 2.6 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.1 1.2 REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1 Genes involved in Signaling by activated point mutants of FGFR1
0.1 2.5 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.1 1.3 REACTOME PYRUVATE METABOLISM Genes involved in Pyruvate metabolism
0.1 0.8 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.1 1.2 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.1 0.7 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.1 1.1 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.1 5.1 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.1 1.7 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.1 1.0 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.1 0.9 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.1 1.4 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.1 1.7 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.1 2.1 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.1 1.3 REACTOME ACYL CHAIN REMODELLING OF PI Genes involved in Acyl chain remodelling of PI
0.1 0.8 REACTOME PROLONGED ERK ACTIVATION EVENTS Genes involved in Prolonged ERK activation events
0.1 1.8 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.1 1.4 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 1.5 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 2.9 REACTOME INTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.0 3.2 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 1.1 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 2.2 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 4.0 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 1.0 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 0.4 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 2.0 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.0 0.7 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.0 2.0 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 1.0 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 2.1 REACTOME MRNA 3 END PROCESSING Genes involved in mRNA 3'-end processing
0.0 1.7 REACTOME SIGNALING BY PDGF Genes involved in Signaling by PDGF
0.0 4.2 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.0 0.9 REACTOME REGULATION OF INSULIN SECRETION BY GLUCAGON LIKE PEPTIDE1 Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1
0.0 2.6 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 2.2 REACTOME GLUCAGON SIGNALING IN METABOLIC REGULATION Genes involved in Glucagon signaling in metabolic regulation
0.0 1.5 REACTOME SIGNALING BY FGFR1 MUTANTS Genes involved in Signaling by FGFR1 mutants
0.0 2.7 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 5.5 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events
0.0 2.4 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 4.5 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 1.0 REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.0 0.6 REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.0 0.6 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.0 0.3 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 2.2 REACTOME SIGNALING BY SCF KIT Genes involved in Signaling by SCF-KIT
0.0 0.9 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 0.2 REACTOME G ALPHA1213 SIGNALLING EVENTS Genes involved in G alpha (12/13) signalling events
0.0 0.4 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.0 0.0 REACTOME OPSINS Genes involved in Opsins
0.0 11.3 REACTOME GENERIC TRANSCRIPTION PATHWAY Genes involved in Generic Transcription Pathway
0.0 1.2 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 0.1 REACTOME THROMBOXANE SIGNALLING THROUGH TP RECEPTOR Genes involved in Thromboxane signalling through TP receptor
0.0 0.6 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.0 0.4 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.0 1.8 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 0.4 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 0.2 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 0.9 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.4 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 0.1 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.5 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.0 0.2 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.0 0.2 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha