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SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for GLIS2

Z-value: 2.11

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Transcription factors associated with GLIS2

Gene Symbol Gene ID Gene Info
ENSG00000126603.4 GLIS family zinc finger 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
GLIS2hg19_v2_chr16_+_4382225_43822250.861.2e-06Click!

Activity profile of GLIS2 motif

Sorted Z-values of GLIS2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr19_+_55795493 16.67 ENST00000309383.1
BR serine/threonine kinase 1
chrX_-_30326445 9.25 ENST00000378963.1
nuclear receptor subfamily 0, group B, member 1
chr11_+_844067 8.34 ENST00000397406.1
ENST00000409543.2
ENST00000525201.1
tetraspanin 4
chr19_+_45417504 8.19 ENST00000588750.1
ENST00000588802.1
apolipoprotein C-I
chr6_-_32908792 8.13 ENST00000418107.2
major histocompatibility complex, class II, DM beta
chr11_-_117695449 8.00 ENST00000292079.2
FXYD domain containing ion transport regulator 2
chr19_+_45417921 7.56 ENST00000252491.4
ENST00000592885.1
ENST00000589781.1
apolipoprotein C-I
chr2_+_37571717 7.27 ENST00000338415.3
ENST00000404976.1
glutaminyl-peptide cyclotransferase
chr19_+_45973120 7.11 ENST00000592811.1
ENST00000586615.1
FBJ murine osteosarcoma viral oncogene homolog B
chr19_+_45417812 6.80 ENST00000592535.1
apolipoprotein C-I
chr17_+_41158742 6.80 ENST00000415816.2
ENST00000438323.2
interferon-induced protein 35
chr12_+_57853918 6.77 ENST00000532291.1
ENST00000543426.1
ENST00000228682.2
ENST00000546141.1
GLI family zinc finger 1
chr16_-_29910365 6.63 ENST00000346932.5
ENST00000350527.3
ENST00000537485.1
ENST00000568380.1
seizure related 6 homolog (mouse)-like 2
chr19_+_45418067 6.39 ENST00000589078.1
ENST00000586638.1
apolipoprotein C-I
chr12_+_57998595 6.34 ENST00000337737.3
ENST00000548198.1
ENST00000551632.1
deltex homolog 3 (Drosophila)
chr19_-_50979981 6.26 ENST00000595790.1
ENST00000600100.1
family with sequence similarity 71, member E1
chr5_-_176836577 6.24 ENST00000253496.3
coagulation factor XII (Hageman factor)
chr3_+_151531810 6.21 ENST00000232892.7
arylacetamide deacetylase
chr19_+_2249308 5.79 ENST00000592877.1
ENST00000221496.4
anti-Mullerian hormone
chr16_+_2198604 5.61 ENST00000210187.6
RAB26, member RAS oncogene family
chr3_+_151531859 5.52 ENST00000488869.1
arylacetamide deacetylase
chr9_+_135037334 5.20 ENST00000393229.3
ENST00000360670.3
ENST00000393228.4
ENST00000372179.3
netrin G2
chr2_+_37571845 5.17 ENST00000537448.1
glutaminyl-peptide cyclotransferase
chr16_-_29910853 5.07 ENST00000308713.5
seizure related 6 homolog (mouse)-like 2
chr11_+_1244288 5.06 ENST00000529681.1
ENST00000447027.1
mucin 5B, oligomeric mucus/gel-forming
chr12_+_57998400 4.80 ENST00000548804.1
ENST00000550596.1
ENST00000551835.1
ENST00000549583.1
deltex homolog 3 (Drosophila)
chr6_-_32908765 4.72 ENST00000416244.2
major histocompatibility complex, class II, DM beta
chr1_-_186649543 4.63 ENST00000367468.5
prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
chr16_+_67198683 4.58 ENST00000517685.1
ENST00000521374.1
ENST00000584272.1
heat shock transcription factor 4
chr19_-_55669093 4.46 ENST00000344887.5
troponin I type 3 (cardiac)
chr1_+_186649754 4.27 ENST00000608917.1
RP5-973M2.2
chr19_+_782755 4.24 ENST00000606242.1
ENST00000586061.1
AC006273.5
chr22_-_38484922 4.20 ENST00000428572.1
BAI1-associated protein 2-like 2
chr19_+_45973360 4.03 ENST00000589593.1
FBJ murine osteosarcoma viral oncogene homolog B
chr19_+_17858509 4.02 ENST00000594202.1
ENST00000252771.7
ENST00000389133.4
FCH domain only 1
chr19_-_55791058 4.00 ENST00000587959.1
ENST00000585927.1
ENST00000587922.1
ENST00000585698.1
HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1
chr11_-_615942 3.90 ENST00000397562.3
ENST00000330243.5
ENST00000397570.1
ENST00000397574.2
interferon regulatory factor 7
chr10_+_133918175 3.89 ENST00000298622.4
Janus kinase and microtubule interacting protein 3
chr16_+_765092 3.80 ENST00000568223.2
meteorin, glial cell differentiation regulator
chr19_+_48828582 3.79 ENST00000270221.6
ENST00000596315.1
epithelial membrane protein 3
chr19_-_55791431 3.75 ENST00000593263.1
ENST00000376343.3
HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1
chr14_+_103566481 3.67 ENST00000380069.3
exocyst complex component 3-like 4
chr16_+_69458428 3.55 ENST00000512062.1
ENST00000307892.8
cytochrome b5 type B (outer mitochondrial membrane)
chr7_+_99746514 3.45 ENST00000341942.5
ENST00000441173.1
late endosomal/lysosomal adaptor, MAPK and MTOR activator 4
chr19_+_56159509 3.43 ENST00000586790.1
ENST00000591578.1
ENST00000588740.1
coiled-coil domain containing 106
chr19_+_45254529 3.42 ENST00000444487.1
B-cell CLL/lymphoma 3
chr20_+_33814457 3.36 ENST00000246186.6
matrix metallopeptidase 24 (membrane-inserted)
chr16_+_69458537 3.31 ENST00000515314.1
ENST00000561792.1
ENST00000568237.1
cytochrome b5 type B (outer mitochondrial membrane)
chr19_+_36236491 3.30 ENST00000591949.1
presenilin enhancer gamma secretase subunit
chr14_+_105559784 3.24 ENST00000548104.1
RP11-44N21.1
chr11_-_615570 3.23 ENST00000525445.1
ENST00000348655.6
ENST00000397566.1
interferon regulatory factor 7
chr2_-_179343226 3.17 ENST00000434643.2
FK506 binding protein 7
chr7_-_73133959 3.14 ENST00000395155.3
ENST00000395154.3
ENST00000222812.3
ENST00000395156.3
syntaxin 1A (brain)
chr12_+_58003935 3.10 ENST00000333972.7
Rho guanine nucleotide exchange factor (GEF) 25
chr20_+_48807351 3.09 ENST00000303004.3
CCAAT/enhancer binding protein (C/EBP), beta
chr5_+_139027877 3.08 ENST00000302517.3
CXXC finger protein 5
chr19_-_55791540 3.06 ENST00000433386.2
HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1
chr19_+_48824711 3.01 ENST00000599704.1
epithelial membrane protein 3
chr2_-_45162783 2.99 ENST00000432125.2
RP11-89K21.1
chr19_-_17799008 2.97 ENST00000519716.2
unc-13 homolog A (C. elegans)
chr11_+_66624527 2.92 ENST00000393952.3
leucine rich repeat and fibronectin type III domain containing 4
chr19_+_56159362 2.92 ENST00000593069.1
ENST00000308964.3
coiled-coil domain containing 106
chrX_+_152240819 2.87 ENST00000421798.3
ENST00000535416.1
paraneoplastic Ma antigen family member 6C
paraneoplastic Ma antigen family member 6A
chr19_-_36236292 2.83 ENST00000378975.3
ENST00000412391.2
ENST00000292879.5
U2 small nuclear RNA auxiliary factor 1-like 4
chr11_-_31531121 2.83 ENST00000532287.1
ENST00000526776.1
ENST00000534812.1
ENST00000529749.1
ENST00000278200.1
ENST00000530023.1
ENST00000533642.1
IMP1 inner mitochondrial membrane peptidase-like (S. cerevisiae)
chr19_+_50979753 2.82 ENST00000597426.1
ENST00000334976.6
ENST00000376918.3
ENST00000598585.1
ER membrane protein complex subunit 10
chr2_-_179343268 2.81 ENST00000424785.2
FK506 binding protein 7
chr19_-_821931 2.77 ENST00000359894.2
ENST00000520876.3
ENST00000519502.1
hsa-mir-3187
chrX_+_118370288 2.66 ENST00000535419.1
progesterone receptor membrane component 1
chr19_+_49622646 2.59 ENST00000334186.4
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3
chr11_-_17555421 2.57 ENST00000526181.1
Usher syndrome 1C (autosomal recessive, severe)
chr19_-_44124019 2.49 ENST00000300811.3
zinc finger protein 428
chr19_-_56056888 2.49 ENST00000592464.1
ENST00000420723.3
SH3 domain binding kinase family, member 3
chr12_+_54378923 2.47 ENST00000303460.4
homeobox C10
chr20_+_35974532 2.41 ENST00000373578.2
v-src avian sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog
chr14_-_54418598 2.40 ENST00000609748.1
ENST00000558961.1
bone morphogenetic protein 4
chr10_+_94608245 2.39 ENST00000443748.2
ENST00000260762.6
exocyst complex component 6
chrX_-_153744507 2.39 ENST00000442929.1
ENST00000426266.1
ENST00000359889.5
ENST00000369641.3
ENST00000447601.2
ENST00000434658.2
family with sequence similarity 3, member A
chr17_+_18625336 2.37 ENST00000395671.4
ENST00000571542.1
ENST00000395672.2
ENST00000414850.2
ENST00000424146.2
tripartite motif containing 16-like
chrX_-_153744434 2.34 ENST00000369643.1
ENST00000393572.1
family with sequence similarity 3, member A
chr12_+_57854274 2.33 ENST00000528432.1
GLI family zinc finger 1
chrX_+_46433193 2.33 ENST00000276055.3
carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7
chr19_-_51071302 2.28 ENST00000389201.3
ENST00000600381.1
leucine rich repeat containing 4B
chr19_-_55652290 2.28 ENST00000589745.1
troponin T type 1 (skeletal, slow)
chr17_-_8198636 2.27 ENST00000577745.1
ENST00000579192.1
ENST00000396278.1
solute carrier family 25, member 35
chr12_-_120907374 2.25 ENST00000550458.1
serine/arginine-rich splicing factor 9
chr16_+_691792 2.23 ENST00000307650.4
family with sequence similarity 195, member A
chr11_+_14665263 2.21 ENST00000282096.4
phosphodiesterase 3B, cGMP-inhibited
chr19_+_45251804 2.20 ENST00000164227.5
B-cell CLL/lymphoma 3
chr17_-_42200996 2.16 ENST00000587135.1
ENST00000225983.6
ENST00000393622.2
ENST00000588703.1
histone deacetylase 5
chr5_-_131826457 2.12 ENST00000437654.1
ENST00000245414.4
interferon regulatory factor 1
chrX_-_10557949 2.11 ENST00000380780.1
midline 1 (Opitz/BBB syndrome)
chr22_+_45072925 2.10 ENST00000006251.7
proline rich 5 (renal)
chrX_+_51927919 2.10 ENST00000416960.1
melanoma antigen family D, 4
chr20_-_62203808 2.08 ENST00000467148.1
helicase with zinc finger 2, transcriptional coactivator
chr12_-_58131931 2.07 ENST00000547588.1
ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
chr1_+_201979743 2.07 ENST00000446188.1
E74-like factor 3 (ets domain transcription factor, epithelial-specific )
chr7_-_155601766 2.07 ENST00000430104.1
sonic hedgehog
chr19_+_38397839 2.03 ENST00000222345.6
signal-induced proliferation-associated 1 like 3
chr5_-_140053152 2.03 ENST00000542735.1
DND microRNA-mediated repression inhibitor 1
chr17_+_78075361 2.02 ENST00000577106.1
ENST00000390015.3
glucosidase, alpha; acid
chr8_+_98881268 2.02 ENST00000254898.5
ENST00000524308.1
ENST00000522025.2
matrilin 2
chr1_-_35450897 2.02 ENST00000373337.3
ZMYM6 neighbor
chr14_-_21566731 2.00 ENST00000360947.3
zinc finger protein 219
chr9_+_139847347 1.96 ENST00000371632.3
lipocalin 12
chr19_+_36602104 1.92 ENST00000585332.1
ENST00000262637.4
ovo-like zinc finger 3
chr19_-_55791563 1.91 ENST00000588971.1
ENST00000255631.5
ENST00000587551.1
HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1
chr2_+_242716231 1.88 ENST00000192314.6
galactose-3-O-sulfotransferase 2
chr19_-_8408139 1.86 ENST00000330915.3
ENST00000593649.1
ENST00000595639.1
KN motif and ankyrin repeat domains 3
chr17_-_7120525 1.85 ENST00000447163.1
ENST00000399506.2
ENST00000302955.6
discs, large homolog 4 (Drosophila)
chr2_-_24346218 1.84 ENST00000436622.1
ENST00000313213.4
profilin family, member 4
chr19_-_46405861 1.84 ENST00000322217.5
Myb-related transcription factor, partner of profilin
chr19_-_41256207 1.83 ENST00000598485.2
ENST00000470681.1
ENST00000339153.3
ENST00000598729.1
chromosome 19 open reading frame 54
chr9_+_97766409 1.82 ENST00000425634.2
chromosome 9 open reading frame 3
chr19_+_3539152 1.79 ENST00000329493.5
chromosome 19 open reading frame 71
chr19_+_41103063 1.79 ENST00000308370.7
latent transforming growth factor beta binding protein 4
chr14_-_23426337 1.76 ENST00000342454.8
ENST00000555986.1
ENST00000541587.1
ENST00000554516.1
ENST00000347758.2
ENST00000206474.7
ENST00000555040.1
HAUS augmin-like complex, subunit 4
chr14_-_24615805 1.76 ENST00000560410.1
proteasome (prosome, macropain) activator subunit 2 (PA28 beta)
chr19_+_45458503 1.76 ENST00000337392.5
ENST00000591304.1
cleft lip and palate associated transmembrane protein 1
chr19_+_17858547 1.74 ENST00000600676.1
ENST00000600209.1
ENST00000596309.1
ENST00000598539.1
ENST00000597474.1
ENST00000593385.1
ENST00000598067.1
ENST00000593833.1
FCH domain only 1
chr16_-_18441131 1.73 ENST00000339303.5
nuclear pore complex interacting protein family, member A8
chr6_-_2903514 1.73 ENST00000380698.4
serpin peptidase inhibitor, clade B (ovalbumin), member 9
chr14_-_24615523 1.73 ENST00000559056.1
proteasome (prosome, macropain) activator subunit 2 (PA28 beta)
chr2_-_46769694 1.72 ENST00000522587.1
ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E2
chr17_-_76921459 1.72 ENST00000262768.7
TIMP metallopeptidase inhibitor 2
chr19_+_56159421 1.71 ENST00000587213.1
coiled-coil domain containing 106
chr22_-_21213676 1.71 ENST00000449120.1
phosphatidylinositol 4-kinase, catalytic, alpha
chr17_+_79953310 1.70 ENST00000582355.2
alveolar soft part sarcoma chromosome region, candidate 1
chr6_-_168397757 1.69 ENST00000456585.1
ENST00000414364.1
KIF25 antisense RNA 1
chr10_-_33623564 1.68 ENST00000374875.1
ENST00000374822.4
neuropilin 1
chr19_-_16008880 1.68 ENST00000011989.7
ENST00000221700.6
cytochrome P450, family 4, subfamily F, polypeptide 2
chr17_-_34257771 1.67 ENST00000394529.3
ENST00000293273.6
RAD52 motif 1
chr9_+_139839711 1.66 ENST00000224181.3
complement component 8, gamma polypeptide
chr20_-_30310656 1.65 ENST00000376055.4
BCL2-like 1
chr19_-_55668093 1.65 ENST00000588882.1
ENST00000586858.1
troponin I type 3 (cardiac)
chr11_-_76381029 1.65 ENST00000407242.2
ENST00000421973.1
leucine rich repeat containing 32
chr15_-_68521996 1.65 ENST00000418702.2
ENST00000565471.1
ENST00000564752.1
ENST00000566347.1
ENST00000249806.5
ENST00000562767.1
ceroid-lipofuscinosis, neuronal 6, late infantile, variant
Uncharacterized protein
chr17_+_6939362 1.63 ENST00000308027.6
solute carrier family 16, member 13
chr14_-_23426270 1.63 ENST00000557591.1
ENST00000397409.4
ENST00000490506.1
ENST00000554406.1
HAUS augmin-like complex, subunit 4
chr9_+_133884469 1.63 ENST00000361069.4
laminin, gamma 3
chr2_+_46769798 1.63 ENST00000238738.4
ras homolog family member Q
chr17_+_7210898 1.62 ENST00000572815.1
eukaryotic translation initiation factor 5A
chr7_+_75544397 1.62 ENST00000461988.1
ENST00000419840.1
P450 (cytochrome) oxidoreductase
chrX_+_102631844 1.62 ENST00000372634.1
ENST00000299872.7
nerve growth factor receptor (TNFRSF16) associated protein 1
chr1_+_47901689 1.61 ENST00000334793.5
forkhead box D2
chr11_+_31531291 1.61 ENST00000350638.5
ENST00000379163.5
ENST00000395934.2
elongator acetyltransferase complex subunit 4
chr11_-_627143 1.61 ENST00000176195.3
secretin
chr1_+_201979645 1.59 ENST00000367284.5
ENST00000367283.3
E74-like factor 3 (ets domain transcription factor, epithelial-specific )
chr17_-_34257731 1.58 ENST00000431884.2
ENST00000425909.3
ENST00000394528.3
ENST00000430160.2
RAD52 motif 1
chr2_+_108905325 1.58 ENST00000438339.1
ENST00000409880.1
ENST00000437390.2
sulfotransferase family, cytosolic, 1C, member 2
chr10_+_106014468 1.58 ENST00000369710.4
ENST00000369713.5
ENST00000445155.1
glutathione S-transferase omega 1
chr20_-_30458019 1.58 ENST00000486996.1
ENST00000398084.2
dual specificity phosphatase 15
chr1_-_139379 1.56 ENST00000423372.3
Uncharacterized protein
chr17_-_79166176 1.56 ENST00000571292.1
5-azacytidine induced 1
chr9_+_139846708 1.53 ENST00000371633.3
lipocalin 12
chr14_-_23426322 1.52 ENST00000555367.1
HAUS augmin-like complex, subunit 4
chr22_-_50699972 1.52 ENST00000395778.3
mitogen-activated protein kinase 12
chr19_+_45582453 1.48 ENST00000591607.1
ENST00000591747.1
ENST00000270257.4
ENST00000391951.2
ENST00000587566.1
gem (nuclear organelle) associated protein 7
MAP/microtubule affinity-regulating kinase 4
chr17_+_80416050 1.47 ENST00000579198.1
ENST00000390006.4
ENST00000580296.1
nuclear prelamin A recognition factor
chr12_+_54519842 1.47 ENST00000508564.1
RP11-834C11.4
chr9_+_139839686 1.46 ENST00000371634.2
complement component 8, gamma polypeptide
chr19_+_56186557 1.43 ENST00000270460.6
epsin 1
chr22_+_45072958 1.43 ENST00000403581.1
proline rich 5 (renal)
chr16_+_88493879 1.41 ENST00000565624.1
ENST00000437464.1
zinc finger protein 469
chr12_+_50451331 1.41 ENST00000228468.4
acid-sensing (proton-gated) ion channel 1
chr19_-_19249255 1.40 ENST00000587583.2
ENST00000450333.2
ENST00000587096.1
ENST00000162044.9
ENST00000592369.1
ENST00000587915.1
transmembrane protein 161A
chr11_+_66045634 1.40 ENST00000528852.1
ENST00000311445.6
cornichon family AMPA receptor auxiliary protein 2
chr17_-_7307358 1.39 ENST00000576017.1
ENST00000302422.3
ENST00000535512.1
transmembrane protein 256
TMEM256-PLSCR3 readthrough (NMD candidate)
chr16_-_29415350 1.36 ENST00000524087.1
nuclear pore complex interacting protein family, member B11
chr14_-_23426231 1.35 ENST00000556915.1
HAUS augmin-like complex, subunit 4
chr11_-_64851496 1.34 ENST00000404147.3
ENST00000275517.3
cell division cycle associated 5
chr22_-_18256742 1.32 ENST00000317361.7
BH3 interacting domain death agonist
chr4_-_170679024 1.32 ENST00000393381.2
chromosome 4 open reading frame 27
chr21_+_45148735 1.32 ENST00000327574.4
pyridoxal (pyridoxine, vitamin B6) kinase
chr9_+_134103496 1.30 ENST00000498010.1
ENST00000476004.1
ENST00000528406.1
nucleoporin 214kDa
chr21_-_39288743 1.30 ENST00000609713.1
potassium inwardly-rectifying channel, subfamily J, member 6
chr7_+_150758642 1.30 ENST00000488420.1
solute carrier family 4 (anion exchanger), member 2
chr19_-_17414179 1.29 ENST00000594194.1
ENST00000247706.3
abhydrolase domain containing 8
chr20_-_30310693 1.28 ENST00000307677.4
ENST00000420653.1
BCL2-like 1
chrX_+_48660287 1.28 ENST00000444343.2
ENST00000376610.2
ENST00000334136.5
ENST00000376619.2
histone deacetylase 6
chr16_+_30087288 1.28 ENST00000279387.7
ENST00000562664.1
ENST00000562222.1
protein phosphatase 4, catalytic subunit
chr2_+_108905095 1.26 ENST00000251481.6
ENST00000326853.5
sulfotransferase family, cytosolic, 1C, member 2
chr17_+_73996987 1.26 ENST00000588812.1
ENST00000448471.1
cyclin-dependent kinase 3
chr22_-_50700140 1.26 ENST00000215659.8
mitogen-activated protein kinase 12
chr8_-_103136481 1.26 ENST00000524209.1
ENST00000517822.1
ENST00000523923.1
ENST00000521599.1
ENST00000521964.1
ENST00000311028.3
ENST00000518166.1
neurocalcin delta
chr19_+_56116771 1.26 ENST00000568956.1
zinc finger protein 865
chr7_+_36192758 1.25 ENST00000242108.4
endonuclease/exonuclease/phosphatase family domain containing 1
chr11_+_827248 1.25 ENST00000527089.1
ENST00000530183.1
EF-hand calcium binding domain 4A
chr17_-_79623597 1.24 ENST00000574024.1
ENST00000331056.5
phosphodiesterase 6G, cGMP-specific, rod, gamma
chrX_+_53449805 1.24 ENST00000414955.2
RIB43A domain with coiled-coils 1
chr7_-_752577 1.24 ENST00000544935.1
ENST00000430040.1
ENST00000456696.2
ENST00000406797.1
protein kinase, cAMP-dependent, regulatory, type I, beta
chr16_+_32264040 1.23 ENST00000398664.3
TP53 target 3D
chrX_+_153656978 1.22 ENST00000369762.2
ENST00000422890.1
ATPase, H+ transporting, lysosomal accessory protein 1
chr19_-_3061397 1.22 ENST00000586839.1
amino-terminal enhancer of split
chr10_+_94608218 1.21 ENST00000371543.1
exocyst complex component 6
chr3_-_129513259 1.20 ENST00000329333.5
transmembrane and coiled-coil domain family 1
chrX_+_118108571 1.19 ENST00000304778.7
LON peptidase N-terminal domain and ring finger 3
chr1_+_1950763 1.19 ENST00000378585.4
gamma-aminobutyric acid (GABA) A receptor, delta
chr12_+_133264156 1.18 ENST00000317479.3
ENST00000543589.1
peroxisomal membrane protein 2, 22kDa
chr2_-_208490027 1.17 ENST00000458426.1
ENST00000406927.2
ENST00000425132.1
methyltransferase like 21A

Network of associatons between targets according to the STRING database.

First level regulatory network of GLIS2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
7.2 28.9 GO:0010900 negative regulation of phosphatidylcholine catabolic process(GO:0010900)
4.3 12.9 GO:2001190 positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:2001190)
4.1 12.4 GO:0017186 peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase(GO:0017186)
2.3 9.1 GO:0060032 notochord regression(GO:0060032)
2.1 6.2 GO:0002541 activation of plasma proteins involved in acute inflammatory response(GO:0002541) positive regulation of fibrinolysis(GO:0051919)
1.9 5.8 GO:0007506 gonadal mesoderm development(GO:0007506)
1.9 5.6 GO:0045082 positive regulation of interleukin-10 biosynthetic process(GO:0045082)
1.7 5.0 GO:0090271 positive regulation of fibroblast growth factor production(GO:0090271)
1.5 9.2 GO:0034124 regulation of MyD88-dependent toll-like receptor signaling pathway(GO:0034124)
1.3 11.7 GO:0010898 positive regulation of triglyceride catabolic process(GO:0010898)
1.2 4.7 GO:0061760 antifungal innate immune response(GO:0061760)
0.8 3.1 GO:0010701 positive regulation of norepinephrine secretion(GO:0010701)
0.8 2.3 GO:0043602 nitrate catabolic process(GO:0043602) nitric oxide catabolic process(GO:0046210)
0.7 2.1 GO:0060738 intein-mediated protein splicing(GO:0016539) protein splicing(GO:0030908) positive regulation of immature T cell proliferation in thymus(GO:0033092) right lung development(GO:0060458) primary prostatic bud elongation(GO:0060516) epithelial-mesenchymal signaling involved in prostate gland development(GO:0060738)
0.7 2.0 GO:0043181 vacuolar sequestering(GO:0043181)
0.7 2.0 GO:0009443 pyridoxal 5'-phosphate salvage(GO:0009443)
0.6 2.6 GO:1904106 protein localization to microvillus(GO:1904106)
0.6 2.4 GO:0071393 cellular response to progesterone stimulus(GO:0071393)
0.6 10.0 GO:0030238 male sex determination(GO:0030238)
0.6 1.7 GO:0042270 protection from natural killer cell mediated cytotoxicity(GO:0042270)
0.6 1.7 GO:0032304 negative regulation of icosanoid secretion(GO:0032304)
0.5 1.6 GO:0060455 negative regulation of gastric acid secretion(GO:0060455) regulation of somatostatin secretion(GO:0090273) positive regulation of somatostatin secretion(GO:0090274)
0.5 2.4 GO:0003277 apoptotic process involved in endocardial cushion morphogenesis(GO:0003277) intermediate mesoderm morphogenesis(GO:0048390) intermediate mesoderm formation(GO:0048391) intermediate mesodermal cell differentiation(GO:0048392) regulation of cardiac muscle fiber development(GO:0055018) positive regulation of cardiac muscle fiber development(GO:0055020) bud dilation involved in lung branching(GO:0060503) BMP signaling pathway involved in ureter morphogenesis(GO:0061149) renal system segmentation(GO:0061150) BMP signaling pathway involved in renal system segmentation(GO:0061151) pulmonary artery endothelial tube morphogenesis(GO:0061155) regulation of transcription from RNA polymerase II promoter involved in mesonephros development(GO:0061216) BMP signaling pathway involved in nephric duct formation(GO:0071893) negative regulation of branch elongation involved in ureteric bud branching(GO:0072096) negative regulation of branch elongation involved in ureteric bud branching by BMP signaling pathway(GO:0072097) anterior/posterior pattern specification involved in ureteric bud development(GO:0072099) specification of ureteric bud anterior/posterior symmetry(GO:0072100) specification of ureteric bud anterior/posterior symmetry by BMP signaling pathway(GO:0072101) ureter epithelial cell differentiation(GO:0072192) negative regulation of mesenchymal cell proliferation involved in ureter development(GO:0072200) positive regulation of cell proliferation involved in outflow tract morphogenesis(GO:1901964) cardiac jelly development(GO:1905072) regulation of metanephric S-shaped body morphogenesis(GO:2000004) negative regulation of metanephric S-shaped body morphogenesis(GO:2000005) regulation of metanephric comma-shaped body morphogenesis(GO:2000006) negative regulation of metanephric comma-shaped body morphogenesis(GO:2000007)
0.5 1.8 GO:0070845 misfolded protein transport(GO:0070843) polyubiquitinated protein transport(GO:0070844) polyubiquitinated misfolded protein transport(GO:0070845) Hsp90 deacetylation(GO:0070846)
0.4 1.3 GO:0071921 establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
0.4 3.0 GO:0099525 presynaptic dense core granule exocytosis(GO:0099525)
0.4 1.2 GO:0034164 negative regulation of toll-like receptor 9 signaling pathway(GO:0034164)
0.4 1.2 GO:0002522 leukocyte migration involved in immune response(GO:0002522)
0.4 2.5 GO:0050915 sensory perception of sour taste(GO:0050915)
0.4 8.0 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
0.4 3.0 GO:0060154 cellular process regulating host cell cycle in response to virus(GO:0060154)
0.3 1.4 GO:1902683 regulation of receptor localization to synapse(GO:1902683)
0.3 1.0 GO:0010845 positive regulation of reciprocal meiotic recombination(GO:0010845)
0.3 1.7 GO:0021649 vestibulocochlear nerve structural organization(GO:0021649) positive regulation of cytokine activity(GO:0060301) ganglion morphogenesis(GO:0061552) VEGF-activated neuropilin signaling pathway involved in axon guidance(GO:1902378) dorsal root ganglion morphogenesis(GO:1904835) otic placode development(GO:1905040)
0.3 11.1 GO:0051412 response to corticosterone(GO:0051412)
0.3 0.3 GO:1903903 regulation of establishment of T cell polarity(GO:1903903)
0.3 2.8 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.3 1.7 GO:0032487 regulation of Rap protein signal transduction(GO:0032487)
0.3 2.3 GO:0031444 slow-twitch skeletal muscle fiber contraction(GO:0031444)
0.2 6.1 GO:0001976 neurological system process involved in regulation of systemic arterial blood pressure(GO:0001976)
0.2 0.9 GO:0021849 neuroblast division in subventricular zone(GO:0021849)
0.2 0.9 GO:1990736 positive regulation of regulation of vascular smooth muscle cell membrane depolarization(GO:1904199) regulation of vascular smooth muscle cell membrane depolarization(GO:1990736)
0.2 6.8 GO:0032060 bleb assembly(GO:0032060)
0.2 2.9 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
0.2 16.9 GO:0031572 G2 DNA damage checkpoint(GO:0031572)
0.2 0.6 GO:0051866 general adaptation syndrome(GO:0051866)
0.2 0.8 GO:0006272 leading strand elongation(GO:0006272)
0.2 3.1 GO:1990440 positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)
0.2 4.2 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.2 0.7 GO:0072287 metanephric distal tubule morphogenesis(GO:0072287)
0.2 3.5 GO:0038203 TORC2 signaling(GO:0038203)
0.2 2.2 GO:0043951 negative regulation of cell adhesion mediated by integrin(GO:0033629) negative regulation of cAMP-mediated signaling(GO:0043951)
0.2 3.7 GO:0051601 exocyst localization(GO:0051601)
0.2 1.6 GO:0006452 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.2 0.5 GO:0007057 spindle assembly involved in female meiosis I(GO:0007057)
0.2 2.5 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.2 2.8 GO:0006975 DNA damage induced protein phosphorylation(GO:0006975)
0.2 1.8 GO:0016188 synaptic vesicle maturation(GO:0016188)
0.2 4.6 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.2 1.2 GO:0044375 peroxisome membrane biogenesis(GO:0016557) regulation of peroxisome size(GO:0044375)
0.2 1.7 GO:0031987 locomotion involved in locomotory behavior(GO:0031987)
0.1 0.7 GO:2001137 positive regulation of endocytic recycling(GO:2001137)
0.1 2.6 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.1 0.4 GO:1900108 negative regulation of nodal signaling pathway(GO:1900108)
0.1 5.8 GO:0048268 clathrin coat assembly(GO:0048268)
0.1 3.4 GO:0050961 cell-cell adhesion mediated by cadherin(GO:0044331) detection of temperature stimulus involved in sensory perception(GO:0050961) detection of temperature stimulus involved in sensory perception of pain(GO:0050965)
0.1 1.2 GO:2001206 positive regulation of osteoclast development(GO:2001206)
0.1 1.5 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787)
0.1 1.6 GO:0060316 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809) positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316)
0.1 3.0 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.1 0.6 GO:0036496 regulation of translational initiation by eIF2 alpha dephosphorylation(GO:0036496)
0.1 2.1 GO:0035372 protein localization to microtubule(GO:0035372)
0.1 1.8 GO:0042989 sequestering of actin monomers(GO:0042989)
0.1 1.2 GO:2000210 positive regulation of anoikis(GO:2000210)
0.1 0.7 GO:0070562 regulation of vitamin D receptor signaling pathway(GO:0070562)
0.1 1.2 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.1 1.2 GO:0043129 surfactant homeostasis(GO:0043129)
0.1 8.6 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.1 0.3 GO:0072720 cellular response to mycotoxin(GO:0036146) response to dithiothreitol(GO:0072720)
0.1 1.8 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.1 1.3 GO:0070294 renal sodium ion absorption(GO:0070294)
0.1 2.2 GO:0060965 negative regulation of gene silencing by miRNA(GO:0060965)
0.1 0.5 GO:0046340 diacylglycerol catabolic process(GO:0046340)
0.1 2.2 GO:2000615 regulation of histone H3-K9 acetylation(GO:2000615)
0.1 0.5 GO:0060010 Sertoli cell fate commitment(GO:0060010)
0.1 2.7 GO:0007220 Notch receptor processing(GO:0007220)
0.1 0.3 GO:0070460 thyroid-stimulating hormone secretion(GO:0070460) regulation of thyroid-stimulating hormone secretion(GO:2000612)
0.1 1.7 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.1 1.1 GO:0038003 opioid receptor signaling pathway(GO:0038003)
0.1 0.3 GO:2000870 positive regulation of female gonad development(GO:2000196) regulation of progesterone secretion(GO:2000870)
0.1 0.4 GO:2000866 negative regulation of macrophage chemotaxis(GO:0010760) positive regulation of estrogen secretion(GO:2000863) positive regulation of estradiol secretion(GO:2000866)
0.1 0.8 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.1 0.2 GO:1903215 negative regulation of protein targeting to mitochondrion(GO:1903215)
0.1 0.7 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
0.1 0.3 GO:0034553 respiratory chain complex II assembly(GO:0034552) mitochondrial respiratory chain complex II assembly(GO:0034553) mitochondrial respiratory chain complex II biogenesis(GO:0097032)
0.1 2.3 GO:0006044 N-acetylglucosamine metabolic process(GO:0006044)
0.1 0.5 GO:0019413 acetate biosynthetic process(GO:0019413) acetyl-CoA biosynthetic process from acetate(GO:0019427) propionate metabolic process(GO:0019541) propionate biosynthetic process(GO:0019542)
0.1 1.3 GO:0045023 G0 to G1 transition(GO:0045023)
0.1 0.3 GO:0034699 response to luteinizing hormone(GO:0034699)
0.1 0.4 GO:0035720 intraciliary anterograde transport(GO:0035720) ciliary receptor clustering involved in smoothened signaling pathway(GO:0060830)
0.1 1.3 GO:0060056 mammary gland involution(GO:0060056)
0.1 12.3 GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436)
0.1 0.4 GO:0010157 response to chlorate(GO:0010157)
0.1 1.1 GO:0034501 protein localization to kinetochore(GO:0034501)
0.1 0.6 GO:0019388 galactose catabolic process(GO:0019388)
0.1 0.2 GO:0043012 regulation of fusion of sperm to egg plasma membrane(GO:0043012)
0.1 0.3 GO:0035927 RNA import into mitochondrion(GO:0035927)
0.1 2.0 GO:0051923 sulfation(GO:0051923)
0.1 14.8 GO:0007219 Notch signaling pathway(GO:0007219)
0.1 0.4 GO:0099551 synaptic signaling via neuropeptide(GO:0099538) trans-synaptic signaling by neuropeptide(GO:0099540) trans-synaptic signaling by neuropeptide, modulating synaptic transmission(GO:0099551)
0.1 2.2 GO:0048025 negative regulation of mRNA splicing, via spliceosome(GO:0048025)
0.1 0.4 GO:0060332 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.1 0.6 GO:0061732 mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
0.1 1.8 GO:0033081 regulation of T cell differentiation in thymus(GO:0033081) regulation of thymocyte aggregation(GO:2000398)
0.1 0.6 GO:0051090 regulation of sequence-specific DNA binding transcription factor activity(GO:0051090)
0.1 1.7 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.1 0.9 GO:0034199 activation of protein kinase A activity(GO:0034199)
0.1 6.5 GO:0060337 type I interferon signaling pathway(GO:0060337) cellular response to type I interferon(GO:0071357)
0.1 0.3 GO:0019566 arabinose metabolic process(GO:0019566) L-arabinose metabolic process(GO:0046373)
0.0 2.3 GO:0039703 viral RNA genome replication(GO:0039694) RNA replication(GO:0039703)
0.0 1.0 GO:0001675 acrosome assembly(GO:0001675)
0.0 0.3 GO:0018032 protein amidation(GO:0018032)
0.0 0.3 GO:0043654 recognition of apoptotic cell(GO:0043654)
0.0 1.3 GO:0071277 cellular response to calcium ion(GO:0071277)
0.0 1.8 GO:0030252 growth hormone secretion(GO:0030252)
0.0 0.4 GO:1902659 regulation of glucose mediated signaling pathway(GO:1902659)
0.0 1.7 GO:0090383 ATP hydrolysis coupled proton transport(GO:0015991) phagosome acidification(GO:0090383)
0.0 8.8 GO:0002223 stimulatory C-type lectin receptor signaling pathway(GO:0002223)
0.0 1.0 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0 0.1 GO:0071469 cellular response to alkaline pH(GO:0071469)
0.0 0.8 GO:0000338 protein deneddylation(GO:0000338)
0.0 0.3 GO:0044565 dendritic cell proliferation(GO:0044565)
0.0 1.3 GO:0010569 regulation of double-strand break repair via homologous recombination(GO:0010569)
0.0 2.2 GO:0061462 protein localization to lysosome(GO:0061462)
0.0 1.2 GO:0045745 positive regulation of G-protein coupled receptor protein signaling pathway(GO:0045745)
0.0 1.1 GO:0031115 negative regulation of microtubule polymerization(GO:0031115)
0.0 0.4 GO:0030497 fatty acid elongation(GO:0030497)
0.0 2.3 GO:1904893 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0 0.5 GO:0051024 positive regulation of immunoglobulin secretion(GO:0051024)
0.0 0.9 GO:0007127 meiosis I(GO:0007127)
0.0 0.9 GO:0016578 histone deubiquitination(GO:0016578)
0.0 1.4 GO:1902230 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902230)
0.0 2.1 GO:0043966 histone H3 acetylation(GO:0043966)
0.0 1.2 GO:0061099 negative regulation of protein tyrosine kinase activity(GO:0061099)
0.0 0.2 GO:1903596 regulation of gap junction assembly(GO:1903596)
0.0 0.6 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 0.2 GO:0002159 desmosome assembly(GO:0002159)
0.0 1.0 GO:0070193 synaptonemal complex assembly(GO:0007130) synaptonemal complex organization(GO:0070193)
0.0 0.1 GO:0060011 Sertoli cell proliferation(GO:0060011)
0.0 1.5 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.0 2.0 GO:0003382 epithelial cell morphogenesis(GO:0003382)
0.0 2.0 GO:0008347 glial cell migration(GO:0008347)
0.0 5.2 GO:0007098 centrosome cycle(GO:0007098)
0.0 1.0 GO:0048278 vesicle docking(GO:0048278)
0.0 0.9 GO:0051984 positive regulation of chromosome segregation(GO:0051984)
0.0 0.5 GO:0001514 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.0 1.6 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.0 4.9 GO:0006805 xenobiotic metabolic process(GO:0006805)
0.0 0.2 GO:1901800 positive regulation of proteasomal protein catabolic process(GO:1901800)
0.0 0.1 GO:0036371 protein localization to T-tubule(GO:0036371)
0.0 0.5 GO:0045008 depyrimidination(GO:0045008)
0.0 1.7 GO:0007029 endoplasmic reticulum organization(GO:0007029)
0.0 0.3 GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.0 2.6 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.0 0.5 GO:1901343 negative regulation of vasculature development(GO:1901343)
0.0 0.5 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0 0.5 GO:0045737 positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737)
0.0 0.8 GO:0040018 positive regulation of multicellular organism growth(GO:0040018)
0.0 0.9 GO:0010613 positive regulation of cardiac muscle hypertrophy(GO:0010613) positive regulation of muscle hypertrophy(GO:0014742)
0.0 0.1 GO:1905000 regulation of membrane repolarization during atrial cardiac muscle cell action potential(GO:1905000)
0.0 0.4 GO:0050930 induction of positive chemotaxis(GO:0050930)
0.0 0.3 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.0 0.0 GO:1900226 negative regulation of NLRP3 inflammasome complex assembly(GO:1900226)
0.0 0.2 GO:0006621 protein retention in ER lumen(GO:0006621) maintenance of protein localization in endoplasmic reticulum(GO:0035437)
0.0 0.6 GO:0046710 GDP metabolic process(GO:0046710)
0.0 1.5 GO:0015701 bicarbonate transport(GO:0015701)
0.0 1.8 GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043123)
0.0 0.5 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.0 1.6 GO:0006501 C-terminal protein lipidation(GO:0006501)
0.0 0.8 GO:0030318 melanocyte differentiation(GO:0030318)
0.0 1.6 GO:0009247 glycolipid biosynthetic process(GO:0009247)
0.0 0.4 GO:0045577 regulation of B cell differentiation(GO:0045577)
0.0 0.1 GO:0038165 oncostatin-M-mediated signaling pathway(GO:0038165)
0.0 0.3 GO:0021794 thalamus development(GO:0021794)
0.0 0.9 GO:0000768 syncytium formation by plasma membrane fusion(GO:0000768)
0.0 1.9 GO:0042177 negative regulation of protein catabolic process(GO:0042177)
0.0 1.2 GO:0015909 long-chain fatty acid transport(GO:0015909)
0.0 0.6 GO:0034260 negative regulation of GTPase activity(GO:0034260)
0.0 0.0 GO:0040040 thermosensory behavior(GO:0040040)
0.0 0.2 GO:0033235 positive regulation of protein sumoylation(GO:0033235)
0.0 1.0 GO:0070527 platelet aggregation(GO:0070527)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 5.6 GO:0033257 Bcl3/NF-kappaB2 complex(GO:0033257)
1.2 2.4 GO:0019034 viral replication complex(GO:0019034)
1.0 26.6 GO:0042627 chylomicron(GO:0042627)
1.0 5.1 GO:0070701 mucus layer(GO:0070701)
0.9 2.8 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.7 9.3 GO:0042788 polysomal ribosome(GO:0042788)
0.6 2.6 GO:1990742 microvesicle(GO:1990742)
0.6 3.1 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.6 12.8 GO:0042613 MHC class II protein complex(GO:0042613)
0.6 3.5 GO:0008537 proteasome activator complex(GO:0008537)
0.5 6.9 GO:0070652 HAUS complex(GO:0070652)
0.4 2.5 GO:1990584 cardiac Troponin complex(GO:1990584)
0.4 2.8 GO:0089701 U2AF(GO:0089701)
0.4 3.1 GO:0005579 membrane attack complex(GO:0005579)
0.4 3.0 GO:0044305 calyx of Held(GO:0044305)
0.3 2.0 GO:0061689 tricellular tight junction(GO:0061689)
0.3 8.0 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.3 3.3 GO:0070765 gamma-secretase complex(GO:0070765)
0.3 1.3 GO:1990876 cytoplasmic side of nuclear pore(GO:1990876)
0.3 1.3 GO:0030289 protein phosphatase 4 complex(GO:0030289)
0.2 4.2 GO:0071439 clathrin complex(GO:0071439)
0.2 3.4 GO:0071986 Ragulator complex(GO:0071986)
0.2 3.1 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.2 4.1 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.2 0.8 GO:0031084 BLOC-2 complex(GO:0031084)
0.2 11.3 GO:0097546 ciliary base(GO:0097546)
0.2 2.5 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.2 0.7 GO:0020016 ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018)
0.2 2.8 GO:0072546 ER membrane protein complex(GO:0072546)
0.2 0.9 GO:0019031 viral envelope(GO:0019031) viral membrane(GO:0036338)
0.2 7.2 GO:0000145 exocyst(GO:0000145)
0.2 16.4 GO:0035580 specific granule lumen(GO:0035580)
0.1 0.7 GO:0002133 polycystin complex(GO:0002133)
0.1 1.5 GO:0005638 lamin filament(GO:0005638)
0.1 1.6 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.1 0.7 GO:0005726 perichromatin fibrils(GO:0005726)
0.1 3.5 GO:0031932 TORC2 complex(GO:0031932)
0.1 1.4 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.1 1.5 GO:0097504 Gemini of coiled bodies(GO:0097504)
0.1 0.9 GO:0016272 prefoldin complex(GO:0016272)
0.1 1.6 GO:0005642 annulate lamellae(GO:0005642)
0.1 2.1 GO:0005861 troponin complex(GO:0005861)
0.1 0.8 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.1 1.7 GO:0005883 neurofilament(GO:0005883)
0.1 1.3 GO:0030130 clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.1 2.9 GO:0033178 proton-transporting two-sector ATPase complex, catalytic domain(GO:0033178)
0.1 1.0 GO:0033503 HULC complex(GO:0033503)
0.1 1.0 GO:0000801 central element(GO:0000801)
0.1 0.8 GO:0097486 multivesicular body lumen(GO:0097486)
0.1 23.5 GO:0008021 synaptic vesicle(GO:0008021)
0.1 1.4 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.1 0.9 GO:0072487 MSL complex(GO:0072487)
0.1 1.8 GO:0071004 U2-type prespliceosome(GO:0071004)
0.1 8.9 GO:0005901 caveola(GO:0005901)
0.1 0.4 GO:0005594 collagen type IX trimer(GO:0005594)
0.1 2.4 GO:0005779 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.1 0.9 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.1 0.3 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.1 0.2 GO:0035101 FACT complex(GO:0035101)
0.1 0.9 GO:0032426 stereocilium tip(GO:0032426)
0.1 0.6 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.1 0.9 GO:0042405 nuclear inclusion body(GO:0042405)
0.0 2.7 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.9 GO:0070938 contractile ring(GO:0070938)
0.0 0.6 GO:0042587 glycogen granule(GO:0042587)
0.0 2.2 GO:0032420 stereocilium(GO:0032420)
0.0 3.2 GO:0032592 integral component of mitochondrial membrane(GO:0032592)
0.0 2.1 GO:0030660 Golgi-associated vesicle membrane(GO:0030660)
0.0 0.2 GO:0017102 methionyl glutamyl tRNA synthetase complex(GO:0017102)
0.0 1.2 GO:1902711 GABA-A receptor complex(GO:1902711)
0.0 1.2 GO:0097381 photoreceptor disc membrane(GO:0097381)
0.0 3.3 GO:0043198 dendritic shaft(GO:0043198)
0.0 0.4 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 2.6 GO:0015030 Cajal body(GO:0015030)
0.0 0.5 GO:0097433 dense body(GO:0097433)
0.0 0.9 GO:0034706 sodium channel complex(GO:0034706)
0.0 2.9 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 6.9 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.0 0.3 GO:0031209 SCAR complex(GO:0031209)
0.0 0.9 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 2.5 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 0.5 GO:0030914 STAGA complex(GO:0030914)
0.0 0.5 GO:0005876 spindle microtubule(GO:0005876)
0.0 2.1 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 0.6 GO:0002080 acrosomal membrane(GO:0002080)
0.0 1.9 GO:0035577 azurophil granule membrane(GO:0035577)
0.0 1.7 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0 2.0 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 0.6 GO:0005849 mRNA cleavage factor complex(GO:0005849)
0.0 0.6 GO:0000421 autophagosome membrane(GO:0000421)
0.0 0.5 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 6.4 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 0.9 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 1.4 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 1.7 GO:0034705 potassium channel complex(GO:0034705)
0.0 15.0 GO:0005789 endoplasmic reticulum membrane(GO:0005789)
0.0 1.4 GO:0043204 perikaryon(GO:0043204)
0.0 0.8 GO:0005762 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
4.1 12.4 GO:0016603 glutaminyl-peptide cyclotransferase activity(GO:0016603)
2.7 26.6 GO:0060228 phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
0.9 4.6 GO:0050473 prostaglandin-endoperoxide synthase activity(GO:0004666) arachidonate 15-lipoxygenase activity(GO:0050473)
0.8 2.3 GO:0047726 iron-cytochrome-c reductase activity(GO:0047726)
0.7 2.2 GO:0004119 cGMP-inhibited cyclic-nucleotide phosphodiesterase activity(GO:0004119)
0.7 18.1 GO:0050321 tau-protein kinase activity(GO:0050321)
0.7 2.0 GO:0004574 oligo-1,6-glucosidase activity(GO:0004574)
0.7 2.0 GO:0008478 pyridoxal kinase activity(GO:0008478)
0.6 8.4 GO:0031014 troponin T binding(GO:0031014)
0.6 1.7 GO:0097258 tocopherol omega-hydroxylase activity(GO:0052870) alpha-tocopherol omega-hydroxylase activity(GO:0052871) 20-hydroxy-leukotriene B4 omega oxidase activity(GO:0097258) 20-aldehyde-leukotriene B4 20-monooxygenase activity(GO:0097259)
0.5 1.8 GO:0031812 G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
0.4 2.5 GO:0044736 acid-sensing ion channel activity(GO:0044736)
0.4 1.6 GO:0032427 GBD domain binding(GO:0032427)
0.4 12.4 GO:0023026 MHC class II protein complex binding(GO:0023026)
0.4 3.5 GO:0061133 endopeptidase activator activity(GO:0061133)
0.4 8.0 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.4 12.3 GO:0004806 triglyceride lipase activity(GO:0004806)
0.4 5.8 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.3 2.8 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.3 2.3 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.3 2.4 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.3 1.1 GO:0004803 transposase activity(GO:0004803)
0.3 1.6 GO:0045174 oxidoreductase activity, acting on a sulfur group of donors, quinone or similar compound as acceptor(GO:0016672) glutathione dehydrogenase (ascorbate) activity(GO:0045174) methylarsonate reductase activity(GO:0050610)
0.3 1.8 GO:0042903 tubulin deacetylase activity(GO:0042903)
0.3 3.0 GO:0051434 BH3 domain binding(GO:0051434)
0.2 3.1 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.2 10.1 GO:0000217 DNA secondary structure binding(GO:0000217)
0.2 2.2 GO:0001025 RNA polymerase III transcription factor binding(GO:0001025)
0.2 6.2 GO:0051787 misfolded protein binding(GO:0051787)
0.2 2.4 GO:0071253 connexin binding(GO:0071253)
0.2 2.1 GO:0016015 morphogen activity(GO:0016015)
0.2 0.6 GO:0004739 pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.2 0.7 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.2 0.7 GO:0045131 pre-mRNA branch point binding(GO:0045131)
0.2 1.7 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.2 2.4 GO:0070700 BMP receptor binding(GO:0070700)
0.2 2.0 GO:0004969 histamine receptor activity(GO:0004969)
0.2 1.9 GO:0001733 galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.1 0.6 GO:0003974 UDP-N-acetylglucosamine 4-epimerase activity(GO:0003974) UDP-glucose 4-epimerase activity(GO:0003978)
0.1 1.6 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.1 1.4 GO:0043515 kinetochore binding(GO:0043515)
0.1 1.3 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.1 4.1 GO:0019992 diacylglycerol binding(GO:0019992)
0.1 1.7 GO:0038085 vascular endothelial growth factor binding(GO:0038085)
0.1 3.7 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.1 0.8 GO:0050733 RS domain binding(GO:0050733)
0.1 0.8 GO:0016936 galactoside binding(GO:0016936)
0.1 0.3 GO:0030943 mitochondrion targeting sequence binding(GO:0030943)
0.1 1.1 GO:0004985 opioid receptor activity(GO:0004985)
0.1 0.5 GO:0070051 fibrinogen binding(GO:0070051)
0.1 0.3 GO:0070123 transforming growth factor beta receptor activity, type III(GO:0070123)
0.1 2.8 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.1 1.8 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.1 1.2 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.1 1.1 GO:0048487 beta-tubulin binding(GO:0048487)
0.1 5.0 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.1 2.7 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.1 3.1 GO:0001848 complement binding(GO:0001848)
0.1 1.8 GO:0005024 transforming growth factor beta-activated receptor activity(GO:0005024)
0.1 1.6 GO:0017070 U6 snRNA binding(GO:0017070)
0.1 1.1 GO:0052658 inositol-polyphosphate 5-phosphatase activity(GO:0004445) inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658)
0.1 0.8 GO:0008310 single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
0.1 1.3 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.1 0.5 GO:0035368 selenocysteine insertion sequence binding(GO:0035368)
0.1 0.4 GO:0017099 very-long-chain-acyl-CoA dehydrogenase activity(GO:0017099)
0.1 1.7 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.1 0.7 GO:0034056 estrogen response element binding(GO:0034056)
0.1 0.4 GO:0060175 brain-derived neurotrophic factor-activated receptor activity(GO:0060175)
0.1 11.9 GO:0020037 heme binding(GO:0020037)
0.1 0.5 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.1 1.8 GO:0035198 miRNA binding(GO:0035198)
0.1 1.5 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.1 0.5 GO:0055104 ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948)
0.1 1.5 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.1 0.4 GO:0005119 smoothened binding(GO:0005119)
0.1 0.5 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.1 0.3 GO:0046556 alpha-L-arabinofuranosidase activity(GO:0046556)
0.1 0.3 GO:0004996 thyroid-stimulating hormone receptor activity(GO:0004996)
0.0 0.3 GO:0004504 peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598)
0.0 1.2 GO:0046961 hydrogen-exporting ATPase activity(GO:0036442) proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.0 0.4 GO:0001165 RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165)
0.0 0.4 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0 0.4 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.0 0.4 GO:0004046 aminoacylase activity(GO:0004046)
0.0 0.9 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 0.6 GO:0039706 co-receptor binding(GO:0039706)
0.0 0.9 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 5.7 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.0 8.8 GO:0005178 integrin binding(GO:0005178)
0.0 0.5 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.0 0.1 GO:0098782 mechanically-gated potassium channel activity(GO:0098782)
0.0 0.4 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.0 0.4 GO:0070097 delta-catenin binding(GO:0070097)
0.0 7.1 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.0 2.2 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.1 GO:0051916 granulocyte colony-stimulating factor binding(GO:0051916)
0.0 1.7 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 1.5 GO:0005521 lamin binding(GO:0005521)
0.0 1.2 GO:0004890 GABA-A receptor activity(GO:0004890)
0.0 1.9 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.6 GO:0017081 chloride channel regulator activity(GO:0017081)
0.0 15.8 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.0 1.2 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 0.3 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 0.6 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.5 GO:0003906 DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
0.0 0.8 GO:0004707 MAP kinase activity(GO:0004707)
0.0 1.3 GO:0030332 cyclin binding(GO:0030332)
0.0 0.6 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.0 0.7 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 1.8 GO:0030507 spectrin binding(GO:0030507)
0.0 0.8 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.0 14.3 GO:0004857 enzyme inhibitor activity(GO:0004857)
0.0 3.4 GO:0051219 phosphoprotein binding(GO:0051219)
0.0 0.2 GO:0010997 anaphase-promoting complex binding(GO:0010997) ubiquitin-protein transferase regulator activity(GO:0055106) ubiquitin-protein transferase activator activity(GO:0097027)
0.0 0.1 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
0.0 0.2 GO:0008240 tripeptidyl-peptidase activity(GO:0008240)
0.0 1.6 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 0.4 GO:0042609 CD4 receptor binding(GO:0042609)
0.0 0.8 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.0 0.3 GO:0004630 phospholipase D activity(GO:0004630) N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0 0.0 GO:0030229 very-low-density lipoprotein particle receptor activity(GO:0030229)
0.0 0.7 GO:0051117 ATPase binding(GO:0051117)
0.0 0.6 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 6.8 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 0.1 GO:0051734 ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
0.0 0.9 GO:0001046 core promoter sequence-specific DNA binding(GO:0001046)
0.0 0.9 GO:0008378 galactosyltransferase activity(GO:0008378)
0.0 1.0 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 0.1 GO:0051400 BH domain binding(GO:0051400)
0.0 0.9 GO:0005272 sodium channel activity(GO:0005272)
0.0 0.2 GO:0019215 intermediate filament binding(GO:0019215)
0.0 0.2 GO:0031545 peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.0 0.4 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.1 GO:0030171 voltage-gated proton channel activity(GO:0030171)
0.0 0.2 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.6 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 0.1 GO:0051373 FATZ binding(GO:0051373)
0.0 2.8 GO:0000149 SNARE binding(GO:0000149)
0.0 0.3 GO:0001190 transcriptional activator activity, RNA polymerase II transcription factor binding(GO:0001190) transcriptional repressor activity, RNA polymerase II activating transcription factor binding(GO:0098811)
0.0 0.3 GO:0048365 Rac GTPase binding(GO:0048365)
0.0 0.1 GO:0004906 interferon-gamma receptor activity(GO:0004906)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 9.1 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.3 5.8 PID ALK2 PATHWAY ALK2 signaling events
0.2 2.4 PID AVB3 INTEGRIN PATHWAY Integrins in angiogenesis
0.2 5.9 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.2 8.0 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.2 18.1 PID LKB1 PATHWAY LKB1 signaling events
0.1 2.8 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.1 7.7 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.1 3.6 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.1 2.8 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.1 1.8 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.1 1.7 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.1 2.4 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.1 7.1 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.1 1.3 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.1 3.4 PID IL6 7 PATHWAY IL6-mediated signaling events
0.1 4.1 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.1 5.4 PID AP1 PATHWAY AP-1 transcription factor network
0.0 2.1 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.0 2.0 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 3.5 PID MTOR 4PATHWAY mTOR signaling pathway
0.0 3.6 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.0 3.0 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 1.6 ST GA12 PATHWAY G alpha 12 Pathway
0.0 1.8 PID PS1 PATHWAY Presenilin action in Notch and Wnt signaling
0.0 12.8 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 3.1 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 0.4 PID IL2 1PATHWAY IL2-mediated signaling events
0.0 1.2 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.0 1.9 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 1.4 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.0 0.5 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.0 0.7 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 1.0 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.0 1.1 ST T CELL SIGNAL TRANSDUCTION T Cell Signal Transduction
0.0 0.5 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 0.5 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions
0.0 0.5 PID MYC PATHWAY C-MYC pathway
0.0 5.0 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 3.1 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.6 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 1.0 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 0.5 ST INTEGRIN SIGNALING PATHWAY Integrin Signaling Pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 7.1 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.3 6.2 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.2 6.7 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.2 5.2 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
0.1 2.7 REACTOME SIGNALING BY NOTCH2 Genes involved in Signaling by NOTCH2
0.1 0.5 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.1 8.0 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.1 4.8 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.1 2.9 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.1 9.0 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.1 10.4 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.1 2.8 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.1 2.6 REACTOME INFLAMMASOMES Genes involved in Inflammasomes
0.1 2.4 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.1 1.7 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.1 3.5 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.1 11.9 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.1 4.7 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.1 7.5 REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.1 3.0 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.1 2.6 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.1 4.4 REACTOME SCF BETA TRCP MEDIATED DEGRADATION OF EMI1 Genes involved in SCF-beta-TrCP mediated degradation of Emi1
0.1 2.2 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.1 1.7 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.0 2.6 REACTOME GLUCAGON TYPE LIGAND RECEPTORS Genes involved in Glucagon-type ligand receptors
0.0 0.6 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 2.8 REACTOME MRNA 3 END PROCESSING Genes involved in mRNA 3'-end processing
0.0 1.3 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 1.4 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.0 1.0 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 1.2 REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0 0.8 REACTOME REPAIR SYNTHESIS FOR GAP FILLING BY DNA POL IN TC NER Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER
0.0 1.6 REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.0 1.6 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.6 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.3 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.0 3.3 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 2.0 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 1.1 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.4 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.0 1.1 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 0.9 REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.0 0.6 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 0.4 REACTOME NGF SIGNALLING VIA TRKA FROM THE PLASMA MEMBRANE Genes involved in NGF signalling via TRKA from the plasma membrane
0.0 0.6 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.9 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.9 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 1.2 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.0 0.9 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA