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SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for GSC_GSC2

Z-value: 0.73

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Transcription factors associated with GSC_GSC2

Gene Symbol Gene ID Gene Info
GSC
ENSG00000133937.3 goosecoid homeobox
GSC2
ENSG00000063515.2 goosecoid homeobox 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
GSChg19_v2_chr14_-_95236551_952365760.698.1e-04Click!
GSC2hg19_v2_chr22_-_19137796_19137796-0.233.2e-01Click!

Activity profile of GSC_GSC2 motif

Sorted Z-values of GSC_GSC2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr11_+_61522844 3.09 ENST00000265460.5
MYRF
myelin regulatory factor
chr15_-_27184664 2.83 ENST00000541819.2
GABRB3
gamma-aminobutyric acid (GABA) A receptor, beta 3
chr12_-_49523896 2.33 ENST00000549870.1
TUBA1B
tubulin, alpha 1b
chr16_+_81272287 1.88 ENST00000425577.2
ENST00000564552.1
BCMO1
beta-carotene 15,15'-monooxygenase 1
chr2_-_175711133 1.87 ENST00000409597.1
ENST00000413882.1
CHN1
chimerin 1
chr17_-_19651668 1.52 ENST00000494157.2
ENST00000225740.6
ALDH3A1
aldehyde dehydrogenase 3 family, member A1
chr17_-_19651654 1.48 ENST00000395555.3
ALDH3A1
aldehyde dehydrogenase 3 family, member A1
chr5_+_76114758 1.46 ENST00000514165.1
ENST00000296677.4
F2RL1
coagulation factor II (thrombin) receptor-like 1
chr10_+_104178946 1.43 ENST00000432590.1
FBXL15
F-box and leucine-rich repeat protein 15
chr1_+_153651078 1.41 ENST00000368680.3
NPR1
natriuretic peptide receptor A/guanylate cyclase A (atrionatriuretic peptide receptor A)
chr3_-_149388682 1.41 ENST00000475579.1
WWTR1
WW domain containing transcription regulator 1
chr17_-_19651598 1.39 ENST00000570414.1
ALDH3A1
aldehyde dehydrogenase 3 family, member A1
chr19_+_50183032 1.26 ENST00000527412.1
PRMT1
protein arginine methyltransferase 1
chr1_-_47655686 1.16 ENST00000294338.2
PDZK1IP1
PDZK1 interacting protein 1
chrX_-_10588595 1.12 ENST00000423614.1
ENST00000317552.4
MID1
midline 1 (Opitz/BBB syndrome)
chr3_+_111393501 1.10 ENST00000393934.3
PLCXD2
phosphatidylinositol-specific phospholipase C, X domain containing 2
chr13_-_31191642 1.09 ENST00000405805.1
HMGB1
high mobility group box 1
chr15_+_63050785 1.06 ENST00000472902.1
TLN2
talin 2
chr9_+_103204553 1.02 ENST00000502978.1
ENST00000334943.6
MSANTD3-TMEFF1
TMEFF1
MSANTD3-TMEFF1 readthrough
transmembrane protein with EGF-like and two follistatin-like domains 1
chrX_+_153769446 1.02 ENST00000422680.1
IKBKG
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
chr12_+_7053172 0.96 ENST00000229281.5
C12orf57
chromosome 12 open reading frame 57
chr12_+_78224667 0.95 ENST00000549464.1
NAV3
neuron navigator 3
chr16_-_31076332 0.94 ENST00000539836.3
ENST00000535577.1
ENST00000442862.2
ZNF668
zinc finger protein 668
chr1_+_17248418 0.92 ENST00000375541.5
CROCC
ciliary rootlet coiled-coil, rootletin
chr17_-_4689649 0.89 ENST00000441199.2
ENST00000416307.2
VMO1
vitelline membrane outer layer 1 homolog (chicken)
chrX_+_69509927 0.86 ENST00000374403.3
KIF4A
kinesin family member 4A
chr1_+_200863949 0.85 ENST00000413687.2
C1orf106
chromosome 1 open reading frame 106
chr15_-_52483566 0.85 ENST00000261837.7
GNB5
guanine nucleotide binding protein (G protein), beta 5
chr14_-_101034407 0.85 ENST00000443071.2
ENST00000557378.1
BEGAIN
brain-enriched guanylate kinase-associated
chr2_-_175499294 0.85 ENST00000392547.2
WIPF1
WAS/WASL interacting protein family, member 1
chrX_+_69509870 0.84 ENST00000374388.3
KIF4A
kinesin family member 4A
chrX_-_10588459 0.83 ENST00000380782.2
MID1
midline 1 (Opitz/BBB syndrome)
chr9_-_131486367 0.82 ENST00000372663.4
ENST00000406904.2
ENST00000452105.1
ENST00000372672.2
ENST00000372667.5
ZDHHC12
zinc finger, DHHC-type containing 12
chr1_+_66820058 0.80 ENST00000480109.2
PDE4B
phosphodiesterase 4B, cAMP-specific
chr12_+_7053228 0.79 ENST00000540506.2
C12orf57
chromosome 12 open reading frame 57
chr12_+_104680793 0.79 ENST00000529546.1
ENST00000529751.1
ENST00000540716.1
ENST00000528079.2
ENST00000526580.1
TXNRD1
thioredoxin reductase 1
chr1_+_169079823 0.77 ENST00000367813.3
ATP1B1
ATPase, Na+/K+ transporting, beta 1 polypeptide
chr12_+_104680659 0.76 ENST00000526691.1
ENST00000531691.1
ENST00000388854.3
ENST00000354940.6
ENST00000526390.1
ENST00000531689.1
TXNRD1
thioredoxin reductase 1
chr3_-_49058479 0.74 ENST00000440857.1
DALRD3
DALR anticodon binding domain containing 3
chr1_+_244816371 0.69 ENST00000263831.7
DESI2
desumoylating isopeptidase 2
chr1_+_244214577 0.68 ENST00000358704.4
ZBTB18
zinc finger and BTB domain containing 18
chr2_-_65659762 0.66 ENST00000440972.1
SPRED2
sprouty-related, EVH1 domain containing 2
chr7_-_128415844 0.66 ENST00000249389.2
OPN1SW
opsin 1 (cone pigments), short-wave-sensitive
chr2_+_128175997 0.65 ENST00000234071.3
ENST00000429925.1
ENST00000442644.1
ENST00000453608.2
PROC
protein C (inactivator of coagulation factors Va and VIIIa)
chr19_+_2476116 0.64 ENST00000215631.4
ENST00000587345.1
GADD45B
growth arrest and DNA-damage-inducible, beta
chr16_-_29875057 0.63 ENST00000219789.6
CDIPT
CDP-diacylglycerol--inositol 3-phosphatidyltransferase
chr8_-_80993010 0.62 ENST00000537855.1
ENST00000520527.1
ENST00000517427.1
ENST00000448733.2
ENST00000379097.3
TPD52
tumor protein D52
chr3_+_49058444 0.62 ENST00000326925.6
ENST00000395458.2
NDUFAF3
NADH dehydrogenase (ubiquinone) complex I, assembly factor 3
chr19_+_48325097 0.61 ENST00000221996.7
ENST00000539067.1
CRX
cone-rod homeobox
chr16_-_31076273 0.61 ENST00000426488.2
ZNF668
zinc finger protein 668
chr17_+_12626199 0.61 ENST00000609971.1
AC005358.1
AC005358.1
chr17_+_43318434 0.59 ENST00000587489.1
FMNL1
formin-like 1
chr2_+_120770581 0.58 ENST00000263713.5
EPB41L5
erythrocyte membrane protein band 4.1 like 5
chr5_+_133451254 0.56 ENST00000517851.1
ENST00000521639.1
ENST00000522375.1
ENST00000378560.4
ENST00000432532.2
ENST00000520958.1
ENST00000518915.1
ENST00000395023.1
TCF7
transcription factor 7 (T-cell specific, HMG-box)
chr17_+_77020146 0.56 ENST00000579760.1
C1QTNF1
C1q and tumor necrosis factor related protein 1
chr16_-_29874462 0.53 ENST00000566113.1
ENST00000569956.1
ENST00000570016.1
CDIPT
CDP-diacylglycerol--inositol 3-phosphatidyltransferase
chr17_+_38465441 0.50 ENST00000577646.1
ENST00000254066.5
RARA
retinoic acid receptor, alpha
chr22_-_40929812 0.48 ENST00000422851.1
MKL1
megakaryoblastic leukemia (translocation) 1
chr14_+_31046959 0.47 ENST00000547532.1
ENST00000555429.1
G2E3
G2/M-phase specific E3 ubiquitin protein ligase
chr1_-_21606013 0.47 ENST00000357071.4
ECE1
endothelin converting enzyme 1
chr14_-_23395623 0.46 ENST00000556043.1
PRMT5
protein arginine methyltransferase 5
chr11_-_71752571 0.46 ENST00000544238.1
NUMA1
nuclear mitotic apparatus protein 1
chrX_+_153769409 0.46 ENST00000440286.1
IKBKG
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
chr11_-_71753188 0.46 ENST00000543009.1
NUMA1
nuclear mitotic apparatus protein 1
chr14_+_52327350 0.46 ENST00000555472.1
ENST00000556766.1
GNG2
guanine nucleotide binding protein (G protein), gamma 2
chr14_-_101034811 0.45 ENST00000553553.1
BEGAIN
brain-enriched guanylate kinase-associated
chr9_-_130966497 0.43 ENST00000393608.1
ENST00000372948.3
CIZ1
CDKN1A interacting zinc finger protein 1
chr3_-_19975665 0.43 ENST00000295824.9
ENST00000389256.4
EFHB
EF-hand domain family, member B
chr3_-_170626418 0.42 ENST00000474096.1
ENST00000295822.2
EIF5A2
eukaryotic translation initiation factor 5A2
chr18_-_64271316 0.41 ENST00000540086.1
ENST00000580157.1
CDH19
cadherin 19, type 2
chr9_-_39288092 0.40 ENST00000323947.7
ENST00000297668.6
ENST00000377656.2
ENST00000377659.1
CNTNAP3
contactin associated protein-like 3
chr17_+_16945820 0.39 ENST00000577514.1
MPRIP
myosin phosphatase Rho interacting protein
chr17_+_73521763 0.38 ENST00000167462.5
ENST00000375227.4
ENST00000392550.3
ENST00000578363.1
ENST00000579392.1
LLGL2
lethal giant larvae homolog 2 (Drosophila)
chr16_-_3074231 0.37 ENST00000572355.1
ENST00000248089.3
ENST00000574980.1
ENST00000354679.3
ENST00000396916.1
ENST00000573842.1
HCFC1R1
host cell factor C1 regulator 1 (XPO1 dependent)
chr2_-_27486951 0.36 ENST00000432351.1
SLC30A3
solute carrier family 30 (zinc transporter), member 3
chr9_+_20927764 0.36 ENST00000603044.1
ENST00000604254.1
FOCAD
focadhesin
chr17_+_77020224 0.35 ENST00000339142.2
C1QTNF1
C1q and tumor necrosis factor related protein 1
chr11_-_71752838 0.35 ENST00000537930.1
NUMA1
nuclear mitotic apparatus protein 1
chr2_+_189156389 0.34 ENST00000409843.1
GULP1
GULP, engulfment adaptor PTB domain containing 1
chr7_-_97881429 0.34 ENST00000420697.1
ENST00000379795.3
ENST00000415086.1
ENST00000542604.1
ENST00000447648.2
TECPR1
tectonin beta-propeller repeat containing 1
chr12_-_52604607 0.32 ENST00000551894.1
ENST00000553017.1
C12orf80
chromosome 12 open reading frame 80
chr2_-_220252068 0.32 ENST00000430206.1
ENST00000429013.1
DNPEP
aspartyl aminopeptidase
chr2_+_189156721 0.32 ENST00000409927.1
ENST00000409805.1
GULP1
GULP, engulfment adaptor PTB domain containing 1
chr17_+_77020325 0.31 ENST00000311661.4
C1QTNF1
C1q and tumor necrosis factor related protein 1
chr22_-_29663954 0.31 ENST00000216085.7
RHBDD3
rhomboid domain containing 3
chr9_+_2015335 0.31 ENST00000349721.2
ENST00000357248.2
ENST00000450198.1
SMARCA2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr2_+_120770645 0.31 ENST00000443902.2
EPB41L5
erythrocyte membrane protein band 4.1 like 5
chr2_+_189156586 0.31 ENST00000409830.1
GULP1
GULP, engulfment adaptor PTB domain containing 1
chr14_+_52327109 0.31 ENST00000335281.4
GNG2
guanine nucleotide binding protein (G protein), gamma 2
chrX_+_17653413 0.30 ENST00000398097.3
NHS
Nance-Horan syndrome (congenital cataracts and dental anomalies)
chr8_-_37457350 0.30 ENST00000519691.1
RP11-150O12.3
RP11-150O12.3
chr12_-_12674032 0.29 ENST00000298573.4
DUSP16
dual specificity phosphatase 16
chr1_-_26633480 0.29 ENST00000450041.1
UBXN11
UBX domain protein 11
chr2_+_189156638 0.29 ENST00000410051.1
GULP1
GULP, engulfment adaptor PTB domain containing 1
chr2_+_120517174 0.28 ENST00000263708.2
PTPN4
protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte)
chr14_+_58894404 0.28 ENST00000554463.1
ENST00000555833.1
KIAA0586
KIAA0586
chr18_-_64271363 0.28 ENST00000262150.2
CDH19
cadherin 19, type 2
chr11_-_67120974 0.27 ENST00000539074.1
ENST00000312419.3
POLD4
polymerase (DNA-directed), delta 4, accessory subunit
chr19_-_39340563 0.26 ENST00000601813.1
HNRNPL
heterogeneous nuclear ribonucleoprotein L
chr2_-_14541060 0.26 ENST00000418420.1
ENST00000417751.1
LINC00276
long intergenic non-protein coding RNA 276
chr3_+_36421826 0.26 ENST00000273183.3
STAC
SH3 and cysteine rich domain
chr5_+_5140436 0.25 ENST00000511368.1
ENST00000274181.7
ADAMTS16
ADAM metallopeptidase with thrombospondin type 1 motif, 16
chr2_+_120517717 0.25 ENST00000420482.1
ENST00000488279.2
PTPN4
protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte)
chr16_+_87636474 0.24 ENST00000284262.2
JPH3
junctophilin 3
chr13_+_36050881 0.24 ENST00000537702.1
NBEA
neurobeachin
chrX_+_139791917 0.23 ENST00000607004.1
ENST00000370535.3
LINC00632
long intergenic non-protein coding RNA 632
chr19_-_49843539 0.22 ENST00000602554.1
ENST00000358234.4
CTC-301O7.4
CTC-301O7.4
chr16_+_21623392 0.22 ENST00000562961.1
METTL9
methyltransferase like 9
chr6_-_35480640 0.22 ENST00000428978.1
ENST00000322263.4
TULP1
tubby like protein 1
chr17_+_68100989 0.22 ENST00000585558.1
ENST00000392670.1
KCNJ16
potassium inwardly-rectifying channel, subfamily J, member 16
chr1_+_114522049 0.21 ENST00000369551.1
ENST00000320334.4
OLFML3
olfactomedin-like 3
chr16_-_69373396 0.21 ENST00000562595.1
ENST00000562081.1
ENST00000306875.4
COG8
component of oligomeric golgi complex 8
chr9_+_17135016 0.21 ENST00000425824.1
ENST00000262360.5
ENST00000380641.4
CNTLN
centlein, centrosomal protein
chr1_+_244816237 0.21 ENST00000302550.11
DESI2
desumoylating isopeptidase 2
chr15_+_54901540 0.21 ENST00000539562.2
UNC13C
unc-13 homolog C (C. elegans)
chr9_-_35072585 0.20 ENST00000448530.1
VCP
valosin containing protein
chr12_-_53171128 0.19 ENST00000332411.2
KRT76
keratin 76
chr14_+_32476072 0.18 ENST00000556949.1
RP11-187E13.2
Uncharacterized protein
chr14_-_71107921 0.17 ENST00000553982.1
ENST00000500016.1
CTD-2540L5.5
CTD-2540L5.6
CTD-2540L5.5
CTD-2540L5.6
chr10_-_35104185 0.17 ENST00000374789.3
ENST00000374788.3
ENST00000346874.4
ENST00000374794.3
ENST00000350537.4
ENST00000374790.3
ENST00000374776.1
ENST00000374773.1
ENST00000545693.1
ENST00000545260.1
ENST00000340077.5
PARD3
par-3 family cell polarity regulator
chr17_+_68101117 0.17 ENST00000587698.1
ENST00000587892.1
KCNJ16
potassium inwardly-rectifying channel, subfamily J, member 16
chr2_-_152146385 0.16 ENST00000414946.1
ENST00000243346.5
NMI
N-myc (and STAT) interactor
chr1_+_18957500 0.16 ENST00000375375.3
PAX7
paired box 7
chrX_-_21676442 0.16 ENST00000379499.2
KLHL34
kelch-like family member 34
chr10_-_76868931 0.16 ENST00000372700.3
ENST00000473072.2
ENST00000491677.2
ENST00000607131.1
ENST00000372702.3
DUSP13
dual specificity phosphatase 13
chr9_-_13279563 0.15 ENST00000541718.1
MPDZ
multiple PDZ domain protein
chr19_+_40877583 0.15 ENST00000596470.1
PLD3
phospholipase D family, member 3
chr1_-_11918988 0.15 ENST00000376468.3
NPPB
natriuretic peptide B
chr19_+_46001697 0.15 ENST00000451287.2
ENST00000324688.4
PPM1N
protein phosphatase, Mg2+/Mn2+ dependent, 1N (putative)
chr10_-_116418053 0.15 ENST00000277895.5
ABLIM1
actin binding LIM protein 1
chr11_-_76155700 0.15 ENST00000572035.1
RP11-111M22.3
RP11-111M22.3
chr1_+_114447763 0.15 ENST00000369563.3
DCLRE1B
DNA cross-link repair 1B
chr4_+_103422499 0.15 ENST00000511926.1
ENST00000507079.1
NFKB1
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
chr9_+_116298778 0.14 ENST00000462143.1
RGS3
regulator of G-protein signaling 3
chr18_-_70532906 0.14 ENST00000299430.2
ENST00000397929.1
NETO1
neuropilin (NRP) and tolloid (TLL)-like 1
chr7_-_29152509 0.14 ENST00000448959.1
CPVL
carboxypeptidase, vitellogenic-like
chr12_+_53818855 0.13 ENST00000550839.1
AMHR2
anti-Mullerian hormone receptor, type II
chr14_+_21785693 0.13 ENST00000382933.4
ENST00000557351.1
RPGRIP1
retinitis pigmentosa GTPase regulator interacting protein 1
chr9_-_13279589 0.13 ENST00000319217.7
MPDZ
multiple PDZ domain protein
chr10_-_126849626 0.12 ENST00000530884.1
CTBP2
C-terminal binding protein 2
chr10_-_76868866 0.12 ENST00000607487.1
DUSP13
dual specificity phosphatase 13
chr7_+_138482695 0.12 ENST00000422794.2
ENST00000397602.3
ENST00000442682.2
ENST00000458494.1
ENST00000413208.1
TMEM213
transmembrane protein 213
chr11_-_76155618 0.11 ENST00000530759.1
RP11-111M22.3
RP11-111M22.3
chr3_-_13028536 0.11 ENST00000450726.1
IQSEC1
IQ motif and Sec7 domain 1
chr3_-_179692042 0.11 ENST00000468741.1
PEX5L
peroxisomal biogenesis factor 5-like
chr7_+_116660246 0.11 ENST00000434836.1
ENST00000393443.1
ENST00000465133.1
ENST00000477742.1
ENST00000393447.4
ENST00000393444.3
ST7
suppression of tumorigenicity 7
chr7_-_78400598 0.10 ENST00000536571.1
MAGI2
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr4_-_147442982 0.10 ENST00000511374.1
ENST00000264986.3
SLC10A7
solute carrier family 10, member 7
chr16_+_69373323 0.10 ENST00000254940.5
NIP7
NIP7, nucleolar pre-rRNA processing protein
chr1_-_160313025 0.10 ENST00000368069.3
ENST00000241704.7
COPA
coatomer protein complex, subunit alpha
chr4_-_147442817 0.10 ENST00000507030.1
SLC10A7
solute carrier family 10, member 7
chr3_-_112218205 0.10 ENST00000383680.4
BTLA
B and T lymphocyte associated
chr4_+_169552748 0.09 ENST00000504519.1
ENST00000512127.1
PALLD
palladin, cytoskeletal associated protein
chr9_+_4839762 0.09 ENST00000448872.2
ENST00000441844.1
RCL1
RNA terminal phosphate cyclase-like 1
chr12_-_13248562 0.09 ENST00000457134.2
ENST00000537302.1
GSG1
germ cell associated 1
chr15_+_33603147 0.09 ENST00000415757.3
ENST00000389232.4
RYR3
ryanodine receptor 3
chr17_-_4689727 0.09 ENST00000328739.5
ENST00000354194.4
VMO1
vitelline membrane outer layer 1 homolog (chicken)
chr6_+_121756809 0.09 ENST00000282561.3
GJA1
gap junction protein, alpha 1, 43kDa
chrX_-_138724994 0.09 ENST00000536274.1
MCF2
MCF.2 cell line derived transforming sequence
chr5_-_16738451 0.09 ENST00000274203.9
ENST00000515803.1
MYO10
myosin X
chr10_-_89577910 0.08 ENST00000308448.7
ENST00000541004.1
ATAD1
ATPase family, AAA domain containing 1
chr11_-_8680383 0.08 ENST00000299550.6
TRIM66
tripartite motif containing 66
chrX_-_110655391 0.08 ENST00000356915.2
ENST00000356220.3
DCX
doublecortin
chr7_+_93535866 0.07 ENST00000429473.1
ENST00000430875.1
ENST00000428834.1
GNGT1
guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1
chr10_+_102222798 0.07 ENST00000343737.5
WNT8B
wingless-type MMTV integration site family, member 8B
chr11_+_61129827 0.07 ENST00000542946.1
TMEM138
transmembrane protein 138
chr1_-_201140673 0.07 ENST00000367333.2
TMEM9
transmembrane protein 9
chr1_+_171227069 0.07 ENST00000354841.4
FMO1
flavin containing monooxygenase 1
chr10_+_74451883 0.07 ENST00000373053.3
ENST00000357157.6
MCU
mitochondrial calcium uniporter
chrX_+_100878079 0.07 ENST00000471229.2
ARMCX3
armadillo repeat containing, X-linked 3
chr11_-_40315640 0.07 ENST00000278198.2
LRRC4C
leucine rich repeat containing 4C
chrX_+_15767971 0.07 ENST00000479740.1
ENST00000454127.2
CA5B
carbonic anhydrase VB, mitochondrial
chr16_+_4421841 0.07 ENST00000304735.3
VASN
vasorin
chr14_-_65785502 0.06 ENST00000553754.1
CTD-2509G16.5
CTD-2509G16.5
chr19_-_42931567 0.06 ENST00000244289.4
LIPE
lipase, hormone-sensitive
chr9_+_17134980 0.06 ENST00000380647.3
CNTLN
centlein, centrosomal protein
chr1_+_151682909 0.06 ENST00000326413.3
ENST00000442233.2
RIIAD1
AL589765.1
regulatory subunit of type II PKA R-subunit (RIIa) domain containing 1
Uncharacterized protein; cDNA FLJ36032 fis, clone TESTI2017069
chrY_+_16634483 0.06 ENST00000382872.1
NLGN4Y
neuroligin 4, Y-linked
chr15_+_58430567 0.05 ENST00000536493.1
AQP9
aquaporin 9
chr6_-_35480705 0.05 ENST00000229771.6
TULP1
tubby like protein 1
chr1_+_36024107 0.05 ENST00000437806.1
NCDN
neurochondrin
chr12_-_13248705 0.05 ENST00000396310.2
GSG1
germ cell associated 1
chrX_+_65382381 0.05 ENST00000519389.1
HEPH
hephaestin
chr15_+_58430368 0.05 ENST00000558772.1
ENST00000219919.4
AQP9
aquaporin 9
chr7_+_93535817 0.05 ENST00000248572.5
GNGT1
guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1
chr17_+_44668035 0.05 ENST00000398238.4
ENST00000225282.8
NSF
N-ethylmaleimide-sensitive factor
chr1_+_162351503 0.05 ENST00000458626.2
C1orf226
chromosome 1 open reading frame 226
chrX_+_100333709 0.05 ENST00000372930.4
TMEM35
transmembrane protein 35
chr1_-_26633067 0.04 ENST00000421827.2
ENST00000374215.1
ENST00000374223.1
ENST00000357089.4
ENST00000535108.1
ENST00000314675.7
ENST00000436301.2
ENST00000423664.1
ENST00000374221.3
UBXN11
UBX domain protein 11
chr12_-_13248732 0.04 ENST00000396302.3
GSG1
germ cell associated 1
chr3_-_179691866 0.04 ENST00000464614.1
ENST00000476138.1
ENST00000463761.1
PEX5L
peroxisomal biogenesis factor 5-like
chr12_-_14849470 0.04 ENST00000261170.3
GUCY2C
guanylate cyclase 2C (heat stable enterotoxin receptor)
chr10_-_94003003 0.03 ENST00000412050.4
CPEB3
cytoplasmic polyadenylation element binding protein 3
chrX_-_110655306 0.03 ENST00000371993.2
DCX
doublecortin
chr17_-_40021656 0.03 ENST00000319121.3
KLHL11
kelch-like family member 11
chr10_-_74714533 0.03 ENST00000373032.3
PLA2G12B
phospholipase A2, group XIIB
chrX_+_135278908 0.03 ENST00000539015.1
ENST00000370683.1
FHL1
four and a half LIM domains 1
chr8_+_55528627 0.03 ENST00000220676.1
RP1
retinitis pigmentosa 1 (autosomal dominant)
chrX_+_65382433 0.03 ENST00000374727.3
HEPH
hephaestin
chr1_+_11751748 0.03 ENST00000294485.5
DRAXIN
dorsal inhibitory axon guidance protein

Network of associatons between targets according to the STRING database.

First level regulatory network of GSC_GSC2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.5 GO:0043311 regulation of eosinophil degranulation(GO:0043309) positive regulation of eosinophil degranulation(GO:0043311) positive regulation of eosinophil activation(GO:1902568)
0.3 1.7 GO:0036343 psychomotor behavior(GO:0036343)
0.3 1.1 GO:0032072 plasmacytoid dendritic cell activation(GO:0002270) regulation of restriction endodeoxyribonuclease activity(GO:0032072)
0.3 3.1 GO:0032286 central nervous system myelin maintenance(GO:0032286)
0.2 0.9 GO:0032053 ciliary basal body organization(GO:0032053) positive regulation of protein localization to cilium(GO:1903566)
0.2 1.3 GO:0046985 positive regulation of hemoglobin biosynthetic process(GO:0046985)
0.2 0.6 GO:0044537 regulation of circulating fibrinogen levels(GO:0044537)
0.2 1.2 GO:2000857 positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.1 1.6 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.1 2.0 GO:0035372 protein localization to microtubule(GO:0035372)
0.1 2.5 GO:0071420 cellular response to histamine(GO:0071420)
0.1 1.3 GO:1902363 regulation of spindle elongation(GO:0032887) regulation of mitotic spindle elongation(GO:0032888) anastral spindle assembly(GO:0055048) protein localization to spindle pole body(GO:0071988) regulation of protein localization to spindle pole body(GO:1902363) positive regulation of protein localization to spindle pole body(GO:1902365) positive regulation of mitotic spindle elongation(GO:1902846)
0.1 0.7 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.1 0.8 GO:1903281 protein transport into plasma membrane raft(GO:0044861) positive regulation of calcium:sodium antiporter activity(GO:1903281) positive regulation of potassium ion import(GO:1903288)
0.1 1.5 GO:0001887 selenium compound metabolic process(GO:0001887)
0.1 0.5 GO:0060010 Sertoli cell fate commitment(GO:0060010)
0.1 0.6 GO:0030538 embryonic genitalia morphogenesis(GO:0030538)
0.1 1.7 GO:0051256 mitotic spindle midzone assembly(GO:0051256)
0.1 0.5 GO:0034959 substance P catabolic process(GO:0010814) calcitonin catabolic process(GO:0010816) endothelin maturation(GO:0034959)
0.1 0.6 GO:0046532 regulation of photoreceptor cell differentiation(GO:0046532)
0.1 0.3 GO:0045209 MAPK phosphatase export from nucleus(GO:0045208) MAPK phosphatase export from nucleus, leptomycin B sensitive(GO:0045209)
0.1 1.4 GO:0072257 metanephric nephron tubule epithelial cell differentiation(GO:0072257) regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072307)
0.1 0.2 GO:0072387 flavin adenine dinucleotide metabolic process(GO:0072387)
0.1 0.1 GO:1902612 regulation of anti-Mullerian hormone signaling pathway(GO:1902612) negative regulation of anti-Mullerian hormone signaling pathway(GO:1902613) anti-Mullerian hormone signaling pathway(GO:1990262)
0.1 0.5 GO:0019918 peptidyl-arginine methylation, to symmetrical-dimethyl arginine(GO:0019918)
0.1 0.2 GO:0048733 sebaceous gland development(GO:0048733)
0.1 0.3 GO:0007509 mesoderm migration involved in gastrulation(GO:0007509)
0.1 0.8 GO:1901898 negative regulation of relaxation of muscle(GO:1901078) negative regulation of relaxation of cardiac muscle(GO:1901898)
0.0 0.5 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.0 0.9 GO:1901386 negative regulation of voltage-gated calcium channel activity(GO:1901386)
0.0 0.7 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 0.9 GO:0070431 nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070431)
0.0 1.2 GO:0046341 CDP-diacylglycerol metabolic process(GO:0046341)
0.0 1.1 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0 2.3 GO:0071353 cellular response to interleukin-4(GO:0071353)
0.0 0.3 GO:0032815 negative regulation of natural killer cell activation(GO:0032815)
0.0 1.9 GO:0008045 motor neuron axon guidance(GO:0008045)
0.0 0.2 GO:0032687 negative regulation of interferon-alpha production(GO:0032687)
0.0 4.0 GO:0006081 cellular aldehyde metabolic process(GO:0006081)
0.0 0.1 GO:0045083 negative regulation of interleukin-12 biosynthetic process(GO:0045083)
0.0 0.8 GO:0007191 adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
0.0 0.2 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.0 0.1 GO:2000312 regulation of kainate selective glutamate receptor activity(GO:2000312)
0.0 0.4 GO:0061088 regulation of sequestering of zinc ion(GO:0061088)
0.0 0.6 GO:1900745 positive regulation of p38MAPK cascade(GO:1900745)
0.0 0.3 GO:0097500 receptor localization to nonmotile primary cilium(GO:0097500)
0.0 0.1 GO:0031860 telomeric loop formation(GO:0031627) telomeric 3' overhang formation(GO:0031860)
0.0 0.6 GO:0051014 actin filament severing(GO:0051014)
0.0 0.1 GO:0010652 regulation of cell communication by chemical coupling(GO:0010645) positive regulation of cell communication by chemical coupling(GO:0010652)
0.0 0.8 GO:0010801 negative regulation of peptidyl-threonine phosphorylation(GO:0010801)
0.0 1.5 GO:0035666 TRIF-dependent toll-like receptor signaling pathway(GO:0035666)
0.0 0.3 GO:0002088 lens development in camera-type eye(GO:0002088)
0.0 0.8 GO:0018345 protein palmitoylation(GO:0018345)
0.0 0.1 GO:0015722 canalicular bile acid transport(GO:0015722) pyrimidine nucleobase transport(GO:0015855) purine nucleobase transmembrane transport(GO:1904823)
0.0 0.2 GO:0014816 skeletal muscle satellite cell differentiation(GO:0014816)
0.0 1.0 GO:0030513 positive regulation of BMP signaling pathway(GO:0030513)
0.0 0.2 GO:0016560 protein import into peroxisome matrix, docking(GO:0016560)
0.0 0.3 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.0 0.1 GO:0006452 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.0 0.1 GO:0071286 cellular response to magnesium ion(GO:0071286)
0.0 0.1 GO:0046340 diacylglycerol catabolic process(GO:0046340)
0.0 0.1 GO:0000480 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480)
0.0 0.0 GO:1900365 positive regulation of mRNA polyadenylation(GO:1900365)
0.0 0.1 GO:2000809 positive regulation of synaptic vesicle clustering(GO:2000809)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.3 GO:0055028 cortical microtubule(GO:0055028)
0.1 1.7 GO:0034709 methylosome(GO:0034709)
0.1 2.5 GO:1902711 GABA-A receptor complex(GO:1902711)
0.1 0.5 GO:0031302 intrinsic component of endosome membrane(GO:0031302)
0.1 1.5 GO:0008385 IkappaB kinase complex(GO:0008385)
0.1 0.9 GO:0035253 ciliary rootlet(GO:0035253)
0.0 4.3 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 0.3 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.0 1.5 GO:0031143 pseudopodium(GO:0031143)
0.0 1.4 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.2 GO:1990730 VCP-NSFL1C complex(GO:1990730)
0.0 2.4 GO:0045171 intercellular bridge(GO:0045171)
0.0 0.8 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0 0.6 GO:0032059 bleb(GO:0032059)
0.0 0.8 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 0.2 GO:0044305 calyx of Held(GO:0044305)
0.0 0.9 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 0.2 GO:0030314 junctional membrane complex(GO:0030314)
0.0 1.2 GO:0001917 photoreceptor inner segment(GO:0001917)
0.0 1.5 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.8 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.2 GO:0033269 internode region of axon(GO:0033269)
0.0 0.3 GO:0071564 npBAF complex(GO:0071564)
0.0 0.1 GO:1990246 uniplex complex(GO:1990246)
0.0 0.2 GO:0017119 Golgi transport complex(GO:0017119)
0.0 0.6 GO:0005719 nuclear euchromatin(GO:0005719)
0.0 0.3 GO:0043220 Schmidt-Lanterman incisure(GO:0043220)
0.0 0.2 GO:0097381 photoreceptor disc membrane(GO:0097381)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 4.4 GO:0018479 benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.4 1.2 GO:0003881 CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity(GO:0003881)
0.3 1.5 GO:0098625 methylselenol reductase activity(GO:0098625) methylseleninic acid reductase activity(GO:0098626)
0.3 1.5 GO:1990450 linear polyubiquitin binding(GO:1990450)
0.2 2.5 GO:0022851 GABA-gated chloride ion channel activity(GO:0022851)
0.2 1.5 GO:0015057 thrombin receptor activity(GO:0015057)
0.2 1.7 GO:0044020 histone methyltransferase activity (H4-R3 specific)(GO:0044020)
0.2 1.4 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.2 0.7 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.2 1.1 GO:0010858 calcium-dependent protein kinase regulator activity(GO:0010858)
0.1 0.7 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.1 0.4 GO:0015633 zinc transporting ATPase activity(GO:0015633)
0.1 0.8 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.1 1.4 GO:0005522 profilin binding(GO:0005522)
0.1 0.7 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.1 1.3 GO:0051011 microtubule minus-end binding(GO:0051011)
0.0 0.5 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.0 1.1 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 1.7 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.2 GO:0036435 K48-linked polyubiquitin binding(GO:0036435)
0.0 0.8 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.0 0.5 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 0.1 GO:0005275 amine transmembrane transporter activity(GO:0005275)
0.0 0.1 GO:0005026 transforming growth factor beta receptor activity, type II(GO:0005026)
0.0 1.9 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.1 GO:0048763 calcium-induced calcium release activity(GO:0048763)
0.0 0.3 GO:0097157 pre-mRNA intronic binding(GO:0097157)
0.0 0.8 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 0.8 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.1 GO:0033878 hormone-sensitive lipase activity(GO:0033878)
0.0 0.1 GO:0003963 RNA-3'-phosphate cyclase activity(GO:0003963)
0.0 0.4 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 0.1 GO:0070699 type II activin receptor binding(GO:0070699)
0.0 0.3 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 3.7 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.2 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.0 2.0 GO:0051219 phosphoprotein binding(GO:0051219)
0.0 0.9 GO:0019894 kinesin binding(GO:0019894)
0.0 0.1 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0 0.1 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.0 0.2 GO:0099604 calcium-release channel activity(GO:0015278) ligand-gated calcium channel activity(GO:0099604)
0.0 0.3 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.5 GO:0017046 peptide hormone binding(GO:0017046)
0.0 0.1 GO:0071253 connexin binding(GO:0071253) gap junction channel activity involved in cardiac conduction electrical coupling(GO:0086075)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.6 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 2.3 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 0.8 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.0 1.5 ST GA12 PATHWAY G alpha 12 Pathway
0.0 1.3 PID ARF6 PATHWAY Arf6 signaling events
0.0 1.8 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 0.6 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 0.4 PID CONE PATHWAY Visual signal transduction: Cones

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.5 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.1 1.5 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.1 0.7 REACTOME OPSINS Genes involved in Opsins
0.1 2.3 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.1 1.1 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 1.3 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0 1.3 REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA Genes involved in G beta:gamma signalling through PLC beta
0.0 1.7 REACTOME KINESINS Genes involved in Kinesins
0.0 0.6 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0 1.5 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 1.4 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 1.9 REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D Genes involved in Metabolism of steroid hormones and vitamins A and D
0.0 0.3 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.0 0.4 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 0.7 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 0.8 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.4 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters