ISMARA results: GTF2I

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SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for GTF2I

Z-value: 0.92

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Transcription factors associated with GTF2I

Gene Symbol	Gene ID	Gene Info
GTF2I Ensembl NCBI GeneCards UniProt NextProt	ENSG00000077809.8	general transcription factor IIi

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
GTF2I	hg19_v2_chr7_+_74072288_74072357	0.58	7.0e-03	Click!

Activity profile of GTF2I motif

Sorted Z-values of GTF2I motif

Top targets:

Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr6_+_149638876 Show fit	2.57	ENST00000392282.1	TAB2 Ensembl NCBI GeneCards UniProt NextProt Show fit	TGF-beta activated kinase 1/MAP3K7 binding protein 2
chr17_+_46131912 Show fit	1.57	ENST00000584634.1 ENST00000580050.1	NFE2L1 Ensembl NCBI GeneCards UniProt NextProt Show fit	nuclear factor, erythroid 2-like 1
chr2_-_230786378 Show fit	1.49	ENST00000430954.1	TRIP12 Ensembl NCBI GeneCards UniProt NextProt Show fit	thyroid hormone receptor interactor 12
chr17_+_46131843 Show fit	1.37	ENST00000577411.1	NFE2L1 Ensembl NCBI GeneCards UniProt NextProt Show fit	nuclear factor, erythroid 2-like 1
chr12_+_4382917 Show fit	1.37	ENST00000261254.3	CCND2 Ensembl NCBI GeneCards UniProt NextProt Show fit	cyclin D2
chr15_-_59041954 Show fit	1.30	ENST00000439637.1 ENST00000558004.1	ADAM10 Ensembl NCBI GeneCards UniProt NextProt Show fit	ADAM metallopeptidase domain 10
chr12_-_57030096 Show fit	1.27	ENST00000549506.1	BAZ2A Ensembl NCBI GeneCards UniProt NextProt Show fit	bromodomain adjacent to zinc finger domain, 2A
chr2_-_208030886 Show fit	1.17	ENST00000426163.1	KLF7 Ensembl NCBI GeneCards UniProt NextProt Show fit	Kruppel-like factor 7 (ubiquitous)
chr5_+_149865838 Show fit	1.17	ENST00000519157.1	NDST1 Ensembl NCBI GeneCards UniProt NextProt Show fit	N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
chr1_+_154193643 Show fit	1.15	ENST00000456325.1	UBAP2L Ensembl NCBI GeneCards UniProt NextProt Show fit	ubiquitin associated protein 2-like
chr17_+_46132037 Show fit	1.14	ENST00000582155.1 ENST00000583378.1 ENST00000536222.1	NFE2L1 Ensembl NCBI GeneCards UniProt NextProt Show fit	nuclear factor, erythroid 2-like 1
chr11_-_118661588 Show fit	1.14	ENST00000534980.1 ENST00000526070.2	DDX6 Ensembl NCBI GeneCards UniProt NextProt Show fit	DEAD (Asp-Glu-Ala-Asp) box helicase 6
chr1_+_27022839 Show fit	1.12	ENST00000457599.2	ARID1A Ensembl NCBI GeneCards UniProt NextProt Show fit	AT rich interactive domain 1A (SWI-like)
chr1_+_36024107 Show fit	1.05	ENST00000437806.1	NCDN Ensembl NCBI GeneCards UniProt NextProt Show fit	neurochondrin
chr6_-_10412600 Show fit	1.04	ENST00000379608.3	TFAP2A Ensembl NCBI GeneCards UniProt NextProt Show fit	transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
chr5_-_141257954 Show fit	1.02	ENST00000456271.1 ENST00000394536.3 ENST00000503492.1 ENST00000287008.3	PCDH1 Ensembl NCBI GeneCards UniProt NextProt Show fit	protocadherin 1
chr12_-_124873357 Show fit	1.00	ENST00000448614.1	NCOR2 Ensembl NCBI GeneCards UniProt NextProt Show fit	nuclear receptor corepressor 2
chr6_-_10413112 Show fit	0.93	ENST00000465858.1	TFAP2A Ensembl NCBI GeneCards UniProt NextProt Show fit	transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
chr1_+_157963391 Show fit	0.93	ENST00000359209.6 ENST00000416935.2	KIRREL Ensembl NCBI GeneCards UniProt NextProt Show fit	kin of IRRE like (Drosophila)
chr5_+_149865377 Show fit	0.93	ENST00000522491.1	NDST1 Ensembl NCBI GeneCards UniProt NextProt Show fit	N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
chr15_+_101420028 Show fit	0.90	ENST00000557963.1 ENST00000346623.6	ALDH1A3 Ensembl NCBI GeneCards UniProt NextProt Show fit	aldehyde dehydrogenase 1 family, member A3
chr5_+_137673945 Show fit	0.89	ENST00000513056.1 ENST00000511276.1	FAM53C Ensembl NCBI GeneCards UniProt NextProt Show fit	family with sequence similarity 53, member C
chr1_+_157963063 Show fit	0.88	ENST00000360089.4 ENST00000368173.3 ENST00000392272.2	KIRREL Ensembl NCBI GeneCards UniProt NextProt Show fit	kin of IRRE like (Drosophila)
chr18_+_46065483 Show fit	0.88	ENST00000382998.4	CTIF Ensembl NCBI GeneCards UniProt NextProt Show fit	CBP80/20-dependent translation initiation factor
chr11_+_64950801 Show fit	0.84	ENST00000526468.1	CAPN1 Ensembl NCBI GeneCards UniProt NextProt Show fit	calpain 1, (mu/I) large subunit
chrX_+_123095546 Show fit	0.83	ENST00000371157.3 ENST00000371145.3 ENST00000371144.3	STAG2 Ensembl NCBI GeneCards UniProt NextProt Show fit	stromal antigen 2
chr1_+_223889310 Show fit	0.82	ENST00000434648.1	CAPN2 Ensembl NCBI GeneCards UniProt NextProt Show fit	calpain 2, (m/II) large subunit
chr1_+_201617450 Show fit	0.80	ENST00000295624.6 ENST00000367297.4 ENST00000367300.3	NAV1 Ensembl NCBI GeneCards UniProt NextProt Show fit	neuron navigator 1
chr1_-_68698197 Show fit	0.80	ENST00000370973.2 ENST00000370971.1	WLS Ensembl NCBI GeneCards UniProt NextProt Show fit	wntless Wnt ligand secretion mediator
chr12_-_120554534 Show fit	0.79	ENST00000538903.1 ENST00000534951.1	RAB35 Ensembl NCBI GeneCards UniProt NextProt Show fit	RAB35, member RAS oncogene family
chr12_+_46123682 Show fit	0.79	ENST00000422737.1	ARID2 Ensembl NCBI GeneCards UniProt NextProt Show fit	AT rich interactive domain 2 (ARID, RFX-like)
chr12_-_6484376 Show fit	0.76	ENST00000360168.3 ENST00000358945.3	SCNN1A Ensembl NCBI GeneCards UniProt NextProt Show fit	sodium channel, non-voltage-gated 1 alpha subunit
chr5_+_138629628 Show fit	0.75	ENST00000508689.1 ENST00000514528.1	MATR3 Ensembl NCBI GeneCards UniProt NextProt Show fit	matrin 3
chr2_+_182756615 Show fit	0.75	ENST00000431877.2 ENST00000320370.7	SSFA2 Ensembl NCBI GeneCards UniProt NextProt Show fit	sperm specific antigen 2
chr7_+_100770328 Show fit	0.75	ENST00000223095.4 ENST00000445463.2	SERPINE1 Ensembl NCBI GeneCards UniProt NextProt Show fit	serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
chr6_+_44095263 Show fit	0.74	ENST00000532634.1	TMEM63B Ensembl NCBI GeneCards UniProt NextProt Show fit	transmembrane protein 63B
chr16_+_57662527 Show fit	0.73	ENST00000563374.1 ENST00000568234.1 ENST00000565770.1 ENST00000564338.1 ENST00000566164.1	GPR56 Ensembl NCBI GeneCards UniProt NextProt Show fit	G protein-coupled receptor 56
chr9_+_131445703 Show fit	0.72	ENST00000454747.1	SET Ensembl NCBI GeneCards UniProt NextProt Show fit	SET nuclear oncogene
chr5_+_149980622 Show fit	0.72	ENST00000394243.1	SYNPO Ensembl NCBI GeneCards UniProt NextProt Show fit	synaptopodin
chr17_-_58469687 Show fit	0.72	ENST00000590133.1	USP32 Ensembl NCBI GeneCards UniProt NextProt Show fit	ubiquitin specific peptidase 32
chr9_+_109625378 Show fit	0.72	ENST00000277225.5 ENST00000457913.1 ENST00000472574.1	ZNF462 Ensembl NCBI GeneCards UniProt NextProt Show fit	zinc finger protein 462
chr19_-_51487282 Show fit	0.72	ENST00000595820.1 ENST00000597707.1 ENST00000336317.4	KLK7 Ensembl NCBI GeneCards UniProt NextProt Show fit	kallikrein-related peptidase 7
chr7_-_41740181 Show fit	0.71	ENST00000442711.1	INHBA Ensembl NCBI GeneCards UniProt NextProt Show fit	inhibin, beta A
chr14_-_61191049 Show fit	0.71	ENST00000556952.3	SIX4 Ensembl NCBI GeneCards UniProt NextProt Show fit	SIX homeobox 4
chr14_+_32546145 Show fit	0.71	ENST00000556611.1 ENST00000539826.2	ARHGAP5 Ensembl NCBI GeneCards UniProt NextProt Show fit	Rho GTPase activating protein 5
chr1_+_154193325 Show fit	0.71	ENST00000428931.1 ENST00000441890.1 ENST00000271877.7 ENST00000412596.1 ENST00000368504.1 ENST00000437652.1	UBAP2L Ensembl NCBI GeneCards UniProt NextProt Show fit	ubiquitin associated protein 2-like
chr1_-_27930102 Show fit	0.70	ENST00000247087.5 ENST00000374011.2	AHDC1 Ensembl NCBI GeneCards UniProt NextProt Show fit	AT hook, DNA binding motif, containing 1
chr12_-_52911718 Show fit	0.69	ENST00000548409.1	KRT5 Ensembl NCBI GeneCards UniProt NextProt Show fit	keratin 5
chr17_+_37617721 Show fit	0.69	ENST00000584632.1	CDK12 Ensembl NCBI GeneCards UniProt NextProt Show fit	cyclin-dependent kinase 12
chr2_-_56150910 Show fit	0.67	ENST00000424836.2 ENST00000438672.1 ENST00000440439.1 ENST00000429909.1 ENST00000424207.1 ENST00000452337.1 ENST00000355426.3 ENST00000439193.1 ENST00000421664.1	EFEMP1 Ensembl NCBI GeneCards UniProt NextProt Show fit	EGF containing fibulin-like extracellular matrix protein 1
chr17_-_58469591 Show fit	0.67	ENST00000589335.1	USP32 Ensembl NCBI GeneCards UniProt NextProt Show fit	ubiquitin specific peptidase 32
chr2_+_182756915 Show fit	0.66	ENST00000428267.2	SSFA2 Ensembl NCBI GeneCards UniProt NextProt Show fit	sperm specific antigen 2
chr19_-_51487071 Show fit	0.66	ENST00000391807.1 ENST00000593904.1	KLK7 Ensembl NCBI GeneCards UniProt NextProt Show fit	kallikrein-related peptidase 7
chr11_-_47574664 Show fit	0.66	ENST00000310513.5 ENST00000531165.1	CELF1 Ensembl NCBI GeneCards UniProt NextProt Show fit	CUGBP, Elav-like family member 1
chr4_+_174089951 Show fit	0.65	ENST00000512285.1	GALNT7 Ensembl NCBI GeneCards UniProt NextProt Show fit	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 7 (GalNAc-T7)
chr2_-_208030647 Show fit	0.65	ENST00000309446.6	KLF7 Ensembl NCBI GeneCards UniProt NextProt Show fit	Kruppel-like factor 7 (ubiquitous)
chr12_+_57522692 Show fit	0.64	ENST00000554174.1	LRP1 Ensembl NCBI GeneCards UniProt NextProt Show fit	low density lipoprotein receptor-related protein 1
chr11_-_57089774 Show fit	0.63	ENST00000527207.1	TNKS1BP1 Ensembl NCBI GeneCards UniProt NextProt Show fit	tankyrase 1 binding protein 1, 182kDa
chr9_-_35754253 Show fit	0.61	ENST00000436428.2	MSMP Ensembl NCBI GeneCards UniProt NextProt Show fit	microseminoprotein, prostate associated
chr2_-_230786032 Show fit	0.61	ENST00000428959.1	TRIP12 Ensembl NCBI GeneCards UniProt NextProt Show fit	thyroid hormone receptor interactor 12
chr9_+_110045418 Show fit	0.61	ENST00000419616.1	RAD23B Ensembl NCBI GeneCards UniProt NextProt Show fit	RAD23 homolog B (S. cerevisiae)
chr14_-_21905424 Show fit	0.60	ENST00000553622.1	CHD8 Ensembl NCBI GeneCards UniProt NextProt Show fit	chromodomain helicase DNA binding protein 8
chr12_+_13044787 Show fit	0.60	ENST00000534831.1	GPRC5A Ensembl NCBI GeneCards UniProt NextProt Show fit	G protein-coupled receptor, family C, group 5, member A
chr2_-_227664474 Show fit	0.59	ENST00000305123.5	IRS1 Ensembl NCBI GeneCards UniProt NextProt Show fit	insulin receptor substrate 1
chr11_+_61595572 Show fit	0.59	ENST00000517312.1	FADS2 Ensembl NCBI GeneCards UniProt NextProt Show fit	fatty acid desaturase 2
chr2_-_230786619 Show fit	0.59	ENST00000389045.3 ENST00000409677.1	TRIP12 Ensembl NCBI GeneCards UniProt NextProt Show fit	thyroid hormone receptor interactor 12
chr17_+_7341586 Show fit	0.58	ENST00000575235.1	FGF11 Ensembl NCBI GeneCards UniProt NextProt Show fit	fibroblast growth factor 11
chr17_-_982198 Show fit	0.57	ENST00000571945.1 ENST00000536794.2	ABR Ensembl NCBI GeneCards UniProt NextProt Show fit	active BCR-related
chr5_-_149682447 Show fit	0.57	ENST00000328668.7	ARSI Ensembl NCBI GeneCards UniProt NextProt Show fit	arylsulfatase family, member I
chr1_+_39734131 Show fit	0.57	ENST00000530262.1	MACF1 Ensembl NCBI GeneCards UniProt NextProt Show fit	microtubule-actin crosslinking factor 1
chr14_+_23775971 Show fit	0.57	ENST00000250405.5	BCL2L2 Ensembl NCBI GeneCards UniProt NextProt Show fit	BCL2-like 2
chr13_-_45151259 Show fit	0.57	ENST00000493016.1	TSC22D1 Ensembl NCBI GeneCards UniProt NextProt Show fit	TSC22 domain family, member 1
chr2_-_39664206 Show fit	0.57	ENST00000484274.1	MAP4K3 Ensembl NCBI GeneCards UniProt NextProt Show fit	mitogen-activated protein kinase kinase kinase kinase 3
chr17_+_75316336 Show fit	0.55	ENST00000591934.1	SEPT9 Ensembl NCBI GeneCards UniProt NextProt Show fit	septin 9
chr12_-_96184913 Show fit	0.55	ENST00000538383.1	NTN4 Ensembl NCBI GeneCards UniProt NextProt Show fit	netrin 4
chr3_+_107243204 Show fit	0.55	ENST00000456817.1 ENST00000458458.1	BBX Ensembl NCBI GeneCards UniProt NextProt Show fit	bobby sox homolog (Drosophila)
chr4_-_140477353 Show fit	0.55	ENST00000406354.1 ENST00000506866.2	SETD7 Ensembl NCBI GeneCards UniProt NextProt Show fit	SET domain containing (lysine methyltransferase) 7
chr17_-_935036 Show fit	0.55	ENST00000572441.1 ENST00000543210.2	ABR Ensembl NCBI GeneCards UniProt NextProt Show fit	active BCR-related
chr3_+_184038234 Show fit	0.55	ENST00000427607.1 ENST00000457456.1	EIF4G1 Ensembl NCBI GeneCards UniProt NextProt Show fit	eukaryotic translation initiation factor 4 gamma, 1
chrX_+_123095860 Show fit	0.55	ENST00000428941.1	STAG2 Ensembl NCBI GeneCards UniProt NextProt Show fit	stromal antigen 2
chr17_-_58469329 Show fit	0.54	ENST00000393003.3	USP32 Ensembl NCBI GeneCards UniProt NextProt Show fit	ubiquitin specific peptidase 32
chr9_-_125667494 Show fit	0.54	ENST00000335387.5 ENST00000357244.2 ENST00000373665.2	RC3H2 Ensembl NCBI GeneCards UniProt NextProt Show fit	ring finger and CCCH-type domains 2
chr7_+_100797726 Show fit	0.54	ENST00000429457.1	AP1S1 Ensembl NCBI GeneCards UniProt NextProt Show fit	adaptor-related protein complex 1, sigma 1 subunit
chr12_-_6484715 Show fit	0.54	ENST00000228916.2	SCNN1A Ensembl NCBI GeneCards UniProt NextProt Show fit	sodium channel, non-voltage-gated 1 alpha subunit
chr1_-_247095236 Show fit	0.54	ENST00000478568.1	AHCTF1 Ensembl NCBI GeneCards UniProt NextProt Show fit	AT hook containing transcription factor 1
chr19_+_42773371 Show fit	0.53	ENST00000571942.2	CIC Ensembl NCBI GeneCards UniProt NextProt Show fit	capicua transcriptional repressor
chr17_+_46125685 Show fit	0.52	ENST00000579889.1	NFE2L1 Ensembl NCBI GeneCards UniProt NextProt Show fit	nuclear factor, erythroid 2-like 1
chr5_-_32444828 Show fit	0.52	ENST00000265069.8	ZFR Ensembl NCBI GeneCards UniProt NextProt Show fit	zinc finger RNA binding protein
chr19_-_39340563 Show fit	0.52	ENST00000601813.1	HNRNPL Ensembl NCBI GeneCards UniProt NextProt Show fit	heterogeneous nuclear ribonucleoprotein L
chr19_+_3366547 Show fit	0.51	ENST00000341919.3 ENST00000590282.1 ENST00000443272.2	NFIC Ensembl NCBI GeneCards UniProt NextProt Show fit	nuclear factor I/C (CCAAT-binding transcription factor)
chr22_+_31644388 Show fit	0.51	ENST00000333611.4 ENST00000340552.4	LIMK2 Ensembl NCBI GeneCards UniProt NextProt Show fit	LIM domain kinase 2
chr12_-_12419905 Show fit	0.51	ENST00000535731.1	LRP6 Ensembl NCBI GeneCards UniProt NextProt Show fit	low density lipoprotein receptor-related protein 6
chr2_+_219264762 Show fit	0.51	ENST00000452977.1	CTDSP1 Ensembl NCBI GeneCards UniProt NextProt Show fit	CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1
chr1_+_166808667 Show fit	0.51	ENST00000537173.1 ENST00000536514.1 ENST00000449930.1	POGK Ensembl NCBI GeneCards UniProt NextProt Show fit	pogo transposable element with KRAB domain
chr3_-_120169828 Show fit	0.51	ENST00000424703.2 ENST00000469005.1	FSTL1 Ensembl NCBI GeneCards UniProt NextProt Show fit	follistatin-like 1
chr1_-_150849047 Show fit	0.50	ENST00000354396.2 ENST00000505755.1	ARNT Ensembl NCBI GeneCards UniProt NextProt Show fit	aryl hydrocarbon receptor nuclear translocator
chr4_-_102268708 Show fit	0.50	ENST00000525819.1	PPP3CA Ensembl NCBI GeneCards UniProt NextProt Show fit	protein phosphatase 3, catalytic subunit, alpha isozyme
chr14_-_69261310 Show fit	0.50	ENST00000336440.3	ZFP36L1 Ensembl NCBI GeneCards UniProt NextProt Show fit	ZFP36 ring finger protein-like 1
chr6_-_86353510 Show fit	0.50	ENST00000444272.1	SYNCRIP Ensembl NCBI GeneCards UniProt NextProt Show fit	synaptotagmin binding, cytoplasmic RNA interacting protein
chr9_-_125667618 Show fit	0.50	ENST00000423239.2	RC3H2 Ensembl NCBI GeneCards UniProt NextProt Show fit	ring finger and CCCH-type domains 2
chr5_+_138629389 Show fit	0.50	ENST00000504045.1 ENST00000504311.1 ENST00000502499.1	MATR3 Ensembl NCBI GeneCards UniProt NextProt Show fit	matrin 3
chr12_+_56915713 Show fit	0.49	ENST00000262031.5 ENST00000552247.2	RBMS2 Ensembl NCBI GeneCards UniProt NextProt Show fit	RNA binding motif, single stranded interacting protein 2
chr8_-_41909496 Show fit	0.49	ENST00000265713.2 ENST00000406337.1 ENST00000396930.3 ENST00000485568.1 ENST00000426524.1	KAT6A Ensembl NCBI GeneCards UniProt NextProt Show fit	K(lysine) acetyltransferase 6A
chr7_+_55086703 Show fit	0.49	ENST00000455089.1 ENST00000342916.3 ENST00000344576.2 ENST00000420316.2	EGFR Ensembl NCBI GeneCards UniProt NextProt Show fit	epidermal growth factor receptor
chr15_+_93443419 Show fit	0.49	ENST00000557381.1 ENST00000420239.2	CHD2 Ensembl NCBI GeneCards UniProt NextProt Show fit	chromodomain helicase DNA binding protein 2
chr2_-_230786679 Show fit	0.49	ENST00000543084.1 ENST00000343290.5 ENST00000389044.4 ENST00000283943.5	TRIP12 Ensembl NCBI GeneCards UniProt NextProt Show fit	thyroid hormone receptor interactor 12
chr9_+_112887772 Show fit	0.49	ENST00000259318.7	AKAP2 Ensembl NCBI GeneCards UniProt NextProt Show fit	A kinase (PRKA) anchor protein 2
chr1_+_201617264 Show fit	0.49	ENST00000367296.4	NAV1 Ensembl NCBI GeneCards UniProt NextProt Show fit	neuron navigator 1
chr1_+_160175166 Show fit	0.49	ENST00000368077.1	PEA15 Ensembl NCBI GeneCards UniProt NextProt Show fit	phosphoprotein enriched in astrocytes 15
chr2_-_198364552 Show fit	0.49	ENST00000439605.1 ENST00000418022.1	HSPD1 Ensembl NCBI GeneCards UniProt NextProt Show fit	heat shock 60kDa protein 1 (chaperonin)
chr12_-_120662499 Show fit	0.49	ENST00000552550.1	PXN Ensembl NCBI GeneCards UniProt NextProt Show fit	paxillin
chr6_-_32143828 Show fit	0.48	ENST00000412465.2 ENST00000375107.3	AGPAT1 Ensembl NCBI GeneCards UniProt NextProt Show fit	1-acylglycerol-3-phosphate O-acyltransferase 1
chr1_-_214724566 Show fit	0.48	ENST00000366956.5	PTPN14 Ensembl NCBI GeneCards UniProt NextProt Show fit	protein tyrosine phosphatase, non-receptor type 14
chr12_+_57522439 Show fit	0.48	ENST00000338962.4	LRP1 Ensembl NCBI GeneCards UniProt NextProt Show fit	low density lipoprotein receptor-related protein 1
chr1_+_154975258 Show fit	0.48	ENST00000417934.2	ZBTB7B Ensembl NCBI GeneCards UniProt NextProt Show fit	zinc finger and BTB domain containing 7B
chr5_+_149887672 Show fit	0.47	ENST00000261797.6	NDST1 Ensembl NCBI GeneCards UniProt NextProt Show fit	N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
chr12_-_48213735 Show fit	0.47	ENST00000417902.1 ENST00000417107.1	HDAC7 Ensembl NCBI GeneCards UniProt NextProt Show fit	histone deacetylase 7
chr20_-_49547910 Show fit	0.47	ENST00000396032.3	ADNP Ensembl NCBI GeneCards UniProt NextProt Show fit	activity-dependent neuroprotector homeobox
chr1_-_39407467 Show fit	0.47	ENST00000540558.1	RHBDL2 Ensembl NCBI GeneCards UniProt NextProt Show fit	rhomboid, veinlet-like 2 (Drosophila)
chr2_+_54683419 Show fit	0.47	ENST00000356805.4	SPTBN1 Ensembl NCBI GeneCards UniProt NextProt Show fit	spectrin, beta, non-erythrocytic 1
chr4_-_146859623 Show fit	0.46	ENST00000379448.4 ENST00000513320.1	ZNF827 Ensembl NCBI GeneCards UniProt NextProt Show fit	zinc finger protein 827
chr12_+_56915776 Show fit	0.46	ENST00000550726.1 ENST00000542360.1	RBMS2 Ensembl NCBI GeneCards UniProt NextProt Show fit	RNA binding motif, single stranded interacting protein 2
chr1_-_155532484 Show fit	0.46	ENST00000368346.3 ENST00000548830.1	ASH1L Ensembl NCBI GeneCards UniProt NextProt Show fit	ash1 (absent, small, or homeotic)-like (Drosophila)
chr16_+_57662138 Show fit	0.46	ENST00000562414.1 ENST00000561969.1 ENST00000562631.1 ENST00000563445.1 ENST00000565338.1 ENST00000567702.1	GPR56 Ensembl NCBI GeneCards UniProt NextProt Show fit	G protein-coupled receptor 56
chr1_-_68698222 Show fit	0.46	ENST00000370976.3 ENST00000354777.2 ENST00000262348.4 ENST00000540432.1	WLS Ensembl NCBI GeneCards UniProt NextProt Show fit	wntless Wnt ligand secretion mediator
chr2_-_153573887 Show fit	0.46	ENST00000493468.2 ENST00000545856.1	PRPF40A Ensembl NCBI GeneCards UniProt NextProt Show fit	PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae)
chr7_-_3083573 Show fit	0.46	ENST00000396946.4	CARD11 Ensembl NCBI GeneCards UniProt NextProt Show fit	caspase recruitment domain family, member 11
chr19_-_10679697 Show fit	0.46	ENST00000335766.2	CDKN2D Ensembl NCBI GeneCards UniProt NextProt Show fit	cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
chr20_-_23030296 Show fit	0.46	ENST00000377103.2	THBD Ensembl NCBI GeneCards UniProt NextProt Show fit	thrombomodulin
chr11_-_123065989 Show fit	0.46	ENST00000448775.2	CLMP Ensembl NCBI GeneCards UniProt NextProt Show fit	CXADR-like membrane protein
chr22_-_36236265 Show fit	0.46	ENST00000414461.2 ENST00000416721.2 ENST00000449924.2 ENST00000262829.7 ENST00000397305.3	RBFOX2 Ensembl NCBI GeneCards UniProt NextProt Show fit	RNA binding protein, fox-1 homolog (C. elegans) 2
chr6_+_33378517 Show fit	0.46	ENST00000428274.1	PHF1 Ensembl NCBI GeneCards UniProt NextProt Show fit	PHD finger protein 1
chr12_-_80084333 Show fit	0.45	ENST00000552637.1	PAWR Ensembl NCBI GeneCards UniProt NextProt Show fit	PRKC, apoptosis, WT1, regulator
chrX_+_123095890 Show fit	0.45	ENST00000435215.1	STAG2 Ensembl NCBI GeneCards UniProt NextProt Show fit	stromal antigen 2
chr9_+_124329336 Show fit	0.45	ENST00000394340.3 ENST00000436835.1 ENST00000259371.2	DAB2IP Ensembl NCBI GeneCards UniProt NextProt Show fit	DAB2 interacting protein
chr6_+_10521574 Show fit	0.45	ENST00000495262.1	GCNT2 Ensembl NCBI GeneCards UniProt NextProt Show fit	glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
chr2_+_159313452 Show fit	0.45	ENST00000389757.3 ENST00000389759.3	PKP4 Ensembl NCBI GeneCards UniProt NextProt Show fit	plakophilin 4
chr1_-_151299842 Show fit	0.45	ENST00000438243.2 ENST00000489223.2 ENST00000368873.1 ENST00000430800.1 ENST00000368872.1	PI4KB Ensembl NCBI GeneCards UniProt NextProt Show fit	phosphatidylinositol 4-kinase, catalytic, beta
chr6_+_15401075 Show fit	0.45	ENST00000541660.1	JARID2 Ensembl NCBI GeneCards UniProt NextProt Show fit	jumonji, AT rich interactive domain 2
chr6_-_34664612 Show fit	0.45	ENST00000374023.3 ENST00000374026.3	C6orf106 Ensembl NCBI GeneCards UniProt NextProt Show fit	chromosome 6 open reading frame 106
chr4_-_140477910 Show fit	0.45	ENST00000404104.3	SETD7 Ensembl NCBI GeneCards UniProt NextProt Show fit	SET domain containing (lysine methyltransferase) 7
chr14_-_23446900 Show fit	0.44	ENST00000556731.1	AJUBA Ensembl NCBI GeneCards UniProt NextProt Show fit	ajuba LIM protein
chr15_+_59279851 Show fit	0.44	ENST00000348370.4 ENST00000434298.1 ENST00000559160.1	RNF111 Ensembl NCBI GeneCards UniProt NextProt Show fit	ring finger protein 111
chr11_-_10829851 Show fit	0.44	ENST00000532082.1	EIF4G2 Ensembl NCBI GeneCards UniProt NextProt Show fit	eukaryotic translation initiation factor 4 gamma, 2
chr3_+_189507523 Show fit	0.44	ENST00000437221.1 ENST00000392463.2 ENST00000392461.3 ENST00000449992.1 ENST00000456148.1	TP63 Ensembl NCBI GeneCards UniProt NextProt Show fit	tumor protein p63
chr3_-_47932759 Show fit	0.44	ENST00000441748.2 ENST00000335271.5	MAP4 Ensembl NCBI GeneCards UniProt NextProt Show fit	microtubule-associated protein 4
chr5_-_142784101 Show fit	0.43	ENST00000503201.1 ENST00000502892.1	NR3C1 Ensembl NCBI GeneCards UniProt NextProt Show fit	nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
chr17_+_36584662 Show fit	0.43	ENST00000431231.2 ENST00000437668.3	ARHGAP23 Ensembl NCBI GeneCards UniProt NextProt Show fit	Rho GTPase activating protein 23
chr2_-_20550416 Show fit	0.43	ENST00000403432.1 ENST00000424110.1	PUM2 Ensembl NCBI GeneCards UniProt NextProt Show fit	pumilio RNA-binding family member 2
chr17_-_1928621 Show fit	0.43	ENST00000331238.6	RTN4RL1 Ensembl NCBI GeneCards UniProt NextProt Show fit	reticulon 4 receptor-like 1
chr1_-_150849174 Show fit	0.43	ENST00000515192.1	ARNT Ensembl NCBI GeneCards UniProt NextProt Show fit	aryl hydrocarbon receptor nuclear translocator
chr3_-_25706368 Show fit	0.43	ENST00000424225.1	TOP2B Ensembl NCBI GeneCards UniProt NextProt Show fit	topoisomerase (DNA) II beta 180kDa
chr7_-_55640141 Show fit	0.43	ENST00000452832.1	VOPP1 Ensembl NCBI GeneCards UniProt NextProt Show fit	vesicular, overexpressed in cancer, prosurvival protein 1
chr5_-_81046904 Show fit	0.43	ENST00000515395.1	SSBP2 Ensembl NCBI GeneCards UniProt NextProt Show fit	single-stranded DNA binding protein 2
chr11_-_125366089 Show fit	0.43	ENST00000366139.3 ENST00000278919.3	FEZ1 Ensembl NCBI GeneCards UniProt NextProt Show fit	fasciculation and elongation protein zeta 1 (zygin I)
chr12_-_80084594 Show fit	0.43	ENST00000548426.1	PAWR Ensembl NCBI GeneCards UniProt NextProt Show fit	PRKC, apoptosis, WT1, regulator
chr5_-_171881362 Show fit	0.42	ENST00000519643.1	SH3PXD2B Ensembl NCBI GeneCards UniProt NextProt Show fit	SH3 and PX domains 2B
chr17_+_48133330 Show fit	0.42	ENST00000544892.1	ITGA3 Ensembl NCBI GeneCards UniProt NextProt Show fit	integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
chr1_+_27022485 Show fit	0.42	ENST00000324856.7	ARID1A Ensembl NCBI GeneCards UniProt NextProt Show fit	AT rich interactive domain 1A (SWI-like)
chr6_+_30852130 Show fit	0.42	ENST00000428153.2 ENST00000376568.3 ENST00000452441.1 ENST00000515219.1	DDR1 Ensembl NCBI GeneCards UniProt NextProt Show fit	discoidin domain receptor tyrosine kinase 1
chr2_-_208030295 Show fit	0.42	ENST00000458272.1	KLF7 Ensembl NCBI GeneCards UniProt NextProt Show fit	Kruppel-like factor 7 (ubiquitous)
chr7_+_134551583 Show fit	0.42	ENST00000435928.1	CALD1 Ensembl NCBI GeneCards UniProt NextProt Show fit	caldesmon 1
chr17_-_40540484 Show fit	0.42	ENST00000588969.1	STAT3 Ensembl NCBI GeneCards UniProt NextProt Show fit	signal transducer and activator of transcription 3 (acute-phase response factor)
chr8_-_101962777 Show fit	0.42	ENST00000395951.3	YWHAZ Ensembl NCBI GeneCards UniProt NextProt Show fit	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
chr5_+_131409476 Show fit	0.41	ENST00000296871.2	CSF2 Ensembl NCBI GeneCards UniProt NextProt Show fit	colony stimulating factor 2 (granulocyte-macrophage)
chr11_+_394145 Show fit	0.41	ENST00000528036.1	PKP3 Ensembl NCBI GeneCards UniProt NextProt Show fit	plakophilin 3
chr12_-_56615485 Show fit	0.41	ENST00000549038.1 ENST00000552244.1	RNF41 Ensembl NCBI GeneCards UniProt NextProt Show fit	ring finger protein 41
chr2_-_75788428 Show fit	0.41	ENST00000432649.1	EVA1A Ensembl NCBI GeneCards UniProt NextProt Show fit	eva-1 homolog A (C. elegans)
chr17_-_63052929 Show fit	0.41	ENST00000439174.2	GNA13 Ensembl NCBI GeneCards UniProt NextProt Show fit	guanine nucleotide binding protein (G protein), alpha 13
chr19_-_4065730 Show fit	0.41	ENST00000601588.1	ZBTB7A Ensembl NCBI GeneCards UniProt NextProt Show fit	zinc finger and BTB domain containing 7A
chr22_+_31644309 Show fit	0.41	ENST00000425203.1	LIMK2 Ensembl NCBI GeneCards UniProt NextProt Show fit	LIM domain kinase 2
chr15_+_41523417 Show fit	0.40	ENST00000560397.1	CHP1 Ensembl NCBI GeneCards UniProt NextProt Show fit	calcineurin-like EF-hand protein 1
chr4_+_99182593 Show fit	0.40	ENST00000508213.1 ENST00000408927.3 ENST00000514122.1 ENST00000453712.2 ENST00000511212.1 ENST00000408900.3 ENST00000339360.5	RAP1GDS1 Ensembl NCBI GeneCards UniProt NextProt Show fit	RAP1, GTP-GDP dissociation stimulator 1
chr2_-_75788424 Show fit	0.40	ENST00000410071.1	EVA1A Ensembl NCBI GeneCards UniProt NextProt Show fit	eva-1 homolog A (C. elegans)
chr17_-_40540377 Show fit	0.40	ENST00000404395.3 ENST00000389272.3 ENST00000585517.1 ENST00000588065.1	STAT3 Ensembl NCBI GeneCards UniProt NextProt Show fit	signal transducer and activator of transcription 3 (acute-phase response factor)
chr5_-_81046841 Show fit	0.39	ENST00000509013.2 ENST00000505980.1 ENST00000509053.1	SSBP2 Ensembl NCBI GeneCards UniProt NextProt Show fit	single-stranded DNA binding protein 2
chr18_+_46065393 Show fit	0.39	ENST00000256413.3	CTIF Ensembl NCBI GeneCards UniProt NextProt Show fit	CBP80/20-dependent translation initiation factor
chr14_-_64010006 Show fit	0.39	ENST00000555899.1	PPP2R5E Ensembl NCBI GeneCards UniProt NextProt Show fit	protein phosphatase 2, regulatory subunit B', epsilon isoform
chr5_+_61708488 Show fit	0.39	ENST00000505902.1	IPO11 Ensembl NCBI GeneCards UniProt NextProt Show fit	importin 11
chr5_-_141249154 Show fit	0.39	ENST00000357517.5 ENST00000536585.1	PCDH1 Ensembl NCBI GeneCards UniProt NextProt Show fit	protocadherin 1
chr6_+_30850862 Show fit	0.39	ENST00000504651.1 ENST00000512694.1 ENST00000515233.1	DDR1 Ensembl NCBI GeneCards UniProt NextProt Show fit	discoidin domain receptor tyrosine kinase 1
chr3_-_47484661 Show fit	0.39	ENST00000495603.2	SCAP Ensembl NCBI GeneCards UniProt NextProt Show fit	SREBF chaperone
chr7_+_132937820 Show fit	0.39	ENST00000393161.2 ENST00000253861.4	EXOC4 Ensembl NCBI GeneCards UniProt NextProt Show fit	exocyst complex component 4
chr5_+_148521381 Show fit	0.38	ENST00000504238.1	ABLIM3 Ensembl NCBI GeneCards UniProt NextProt Show fit	actin binding LIM protein family, member 3
chrX_-_20284733 Show fit	0.38	ENST00000438357.1	RPS6KA3 Ensembl NCBI GeneCards UniProt NextProt Show fit	ribosomal protein S6 kinase, 90kDa, polypeptide 3
chr2_-_217236750 Show fit	0.38	ENST00000273067.4	MARCH4 Ensembl NCBI GeneCards UniProt NextProt Show fit	membrane-associated ring finger (C3HC4) 4, E3 ubiquitin protein ligase
chr15_+_64752927 Show fit	0.38	ENST00000416172.1	ZNF609 Ensembl NCBI GeneCards UniProt NextProt Show fit	zinc finger protein 609
chr11_-_118134997 Show fit	0.38	ENST00000278937.2	MPZL2 Ensembl NCBI GeneCards UniProt NextProt Show fit	myelin protein zero-like 2
chr1_+_13910757 Show fit	0.38	ENST00000376061.4 ENST00000513143.1	PDPN Ensembl NCBI GeneCards UniProt NextProt Show fit	podoplanin
chr5_+_34685805 Show fit	0.38	ENST00000508315.1	RAI14 Ensembl NCBI GeneCards UniProt NextProt Show fit	retinoic acid induced 14
chr2_+_182756701 Show fit	0.38	ENST00000409001.1	SSFA2 Ensembl NCBI GeneCards UniProt NextProt Show fit	sperm specific antigen 2
chr8_-_49834299 Show fit	0.38	ENST00000396822.1	SNAI2 Ensembl NCBI GeneCards UniProt NextProt Show fit	snail family zinc finger 2
chr5_+_138089100 Show fit	0.37	ENST00000520339.1 ENST00000355078.5 ENST00000302763.7 ENST00000518910.1	CTNNA1 Ensembl NCBI GeneCards UniProt NextProt Show fit	catenin (cadherin-associated protein), alpha 1, 102kDa
chr12_-_123849374 Show fit	0.37	ENST00000602398.1 ENST00000602750.1	SBNO1 Ensembl NCBI GeneCards UniProt NextProt Show fit	strawberry notch homolog 1 (Drosophila)
chr16_+_57220049 Show fit	0.37	ENST00000562439.1	RSPRY1 Ensembl NCBI GeneCards UniProt NextProt Show fit	ring finger and SPRY domain containing 1
chr10_-_12084770 Show fit	0.37	ENST00000357604.5	UPF2 Ensembl NCBI GeneCards UniProt NextProt Show fit	UPF2 regulator of nonsense transcripts homolog (yeast)
chr2_-_20550382 Show fit	0.37	ENST00000536417.1	PUM2 Ensembl NCBI GeneCards UniProt NextProt Show fit	pumilio RNA-binding family member 2
chr4_-_74124502 Show fit	0.37	ENST00000358602.4 ENST00000330838.6 ENST00000561029.1	ANKRD17 Ensembl NCBI GeneCards UniProt NextProt Show fit	ankyrin repeat domain 17
chr12_+_27677085 Show fit	0.37	ENST00000545334.1 ENST00000540114.1 ENST00000537927.1 ENST00000318304.8 ENST00000535047.1 ENST00000542629.1 ENST00000228425.6	PPFIBP1 Ensembl NCBI GeneCards UniProt NextProt Show fit	PTPRF interacting protein, binding protein 1 (liprin beta 1)
chr4_+_99182519 Show fit	0.37	ENST00000509011.1 ENST00000380158.4 ENST00000264572.7	RAP1GDS1 Ensembl NCBI GeneCards UniProt NextProt Show fit	RAP1, GTP-GDP dissociation stimulator 1

Network of associatons between targets according to the STRING database.

First level regulatory network of GTF2I

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View png image

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	2.0	GO:0021623	optic cup structural organization(GO:0003409) oculomotor nerve morphogenesis(GO:0021622) oculomotor nerve formation(GO:0021623)
0.4	1.8	GO:1905167	positive regulation of lysosomal protein catabolic process(GO:1905167)
0.4	1.4	GO:0019074	viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
0.3	3.4	GO:0033183	negative regulation of histone ubiquitination(GO:0033183) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315)
0.3	1.0	GO:0072365	regulation of cellular ketone metabolic process by negative regulation of transcription from RNA polymerase II promoter(GO:0072365)
0.3	1.7	GO:0051088	PMA-inducible membrane protein ectodomain proteolysis(GO:0051088)
0.3	1.3	GO:0061357	positive regulation of Wnt protein secretion(GO:0061357)
0.3	1.9	GO:0061484	hematopoietic stem cell homeostasis(GO:0061484)
0.3	0.8	GO:0045041	B cell cytokine production(GO:0002368) protein import into mitochondrial intermembrane space(GO:0045041)
0.3	0.8	GO:0001300	chronological cell aging(GO:0001300)
0.3	0.8	GO:0035261	external genitalia morphogenesis(GO:0035261)
0.3	1.0	GO:0007499	ectoderm and mesoderm interaction(GO:0007499)
0.2	1.5	GO:0070384	Harderian gland development(GO:0070384)
0.2	1.7	GO:0006344	maintenance of chromatin silencing(GO:0006344)
0.2	1.0	GO:1905205	positive regulation of connective tissue replacement(GO:1905205)
0.2	0.7	GO:1901420	negative regulation of vitamin D receptor signaling pathway(GO:0070563) negative regulation of response to alcohol(GO:1901420)
0.2	1.4	GO:0002225	positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antimicrobial humoral response(GO:0002760) positive regulation of antibacterial peptide production(GO:0002803)
0.2	0.6	GO:1990764	regulation of myofibroblast contraction(GO:1904328) myofibroblast contraction(GO:1990764)
0.2	2.6	GO:0006477	protein sulfation(GO:0006477)
0.2	0.7	GO:0043006	activation of phospholipase A2 activity by calcium-mediated signaling(GO:0043006)
0.2	0.7	GO:0071894	histone H2B conserved C-terminal lysine ubiquitination(GO:0071894)
0.2	0.7	GO:0045578	negative regulation of B cell differentiation(GO:0045578)
0.2	2.5	GO:0032876	negative regulation of DNA endoreduplication(GO:0032876)
0.2	0.7	GO:0043376	regulation of CD8-positive, alpha-beta T cell differentiation(GO:0043376)
0.2	1.3	GO:0043314	negative regulation of neutrophil degranulation(GO:0043314)
0.1	0.7	GO:0010730	negative regulation of hydrogen peroxide biosynthetic process(GO:0010730) positive regulation of skeletal muscle satellite cell proliferation(GO:1902724) positive regulation of growth factor dependent skeletal muscle satellite cell proliferation(GO:1902728)
0.1	0.8	GO:0042986	positive regulation of amyloid precursor protein biosynthetic process(GO:0042986)
0.1	0.4	GO:0032747	positive regulation of interleukin-23 production(GO:0032747)
0.1	0.4	GO:0002121	inter-male aggressive behavior(GO:0002121)
0.1	2.0	GO:0002191	cap-dependent translational initiation(GO:0002191)
0.1	1.2	GO:0061470	T follicular helper cell differentiation(GO:0061470)
0.1	0.4	GO:0035621	ER to Golgi ceramide transport(GO:0035621)
0.1	0.7	GO:0098886	modification of dendritic spine(GO:0098886)
0.1	1.4	GO:1900246	positive regulation of RIG-I signaling pathway(GO:1900246)
0.1	5.1	GO:0006783	heme biosynthetic process(GO:0006783)
0.1	0.3	GO:0090403	oxidative stress-induced premature senescence(GO:0090403)
0.1	0.7	GO:0021993	initiation of neural tube closure(GO:0021993)
0.1	0.3	GO:0044727	DNA demethylation of male pronucleus(GO:0044727)
0.1	0.4	GO:1902725	negative regulation of satellite cell differentiation(GO:1902725)
0.1	0.3	GO:0050822	peptide stabilization(GO:0050822) peptide antigen stabilization(GO:0050823)
0.1	0.3	GO:0097195	pilomotor reflex(GO:0097195)
0.1	0.3	GO:1901340	negative regulation of store-operated calcium channel activity(GO:1901340)
0.1	0.4	GO:0036483	neuron intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress(GO:0036483) regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903381) negative regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903382)
0.1	0.5	GO:0002528	regulation of vascular permeability involved in acute inflammatory response(GO:0002528)
0.1	1.5	GO:0018026	peptidyl-lysine monomethylation(GO:0018026)
0.1	0.5	GO:1901545	cellular response to raffinose(GO:0097403) response to raffinose(GO:1901545)
0.1	0.3	GO:1903570	regulation of protein kinase D signaling(GO:1903570) positive regulation of protein kinase D signaling(GO:1903572)
0.1	0.5	GO:0090285	negative regulation of protein glycosylation in Golgi(GO:0090285)
0.1	0.5	GO:2001045	negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.1	0.5	GO:0043553	vascular endothelial growth factor receptor-2 signaling pathway(GO:0036324) negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.1	0.3	GO:0060054	positive regulation of epithelial cell proliferation involved in wound healing(GO:0060054)
0.1	1.1	GO:0060982	coronary artery morphogenesis(GO:0060982)
0.1	1.3	GO:0043402	glucocorticoid mediated signaling pathway(GO:0043402)
0.1	1.3	GO:0048227	plasma membrane to endosome transport(GO:0048227)
0.1	0.9	GO:0070934	CRD-mediated mRNA stabilization(GO:0070934)
0.1	0.3	GO:0014707	branchiomeric skeletal muscle development(GO:0014707)
0.1	0.3	GO:0015728	mevalonate transport(GO:0015728) behavioral response to nutrient(GO:0051780)
0.1	0.8	GO:0002159	desmosome assembly(GO:0002159)
0.1	0.2	GO:1904017	cellular response to Thyroglobulin triiodothyronine(GO:1904017)
0.1	1.5	GO:0090050	positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.1	0.3	GO:1900155	regulation of bone trabecula formation(GO:1900154) negative regulation of bone trabecula formation(GO:1900155)
0.1	0.2	GO:0052255	induction by symbiont of host defense response(GO:0044416) induction of host immune response by virus(GO:0046730) active induction of host immune response by virus(GO:0046732) modulation by symbiont of host defense response(GO:0052031) induction by organism of defense response of other organism involved in symbiotic interaction(GO:0052251) modulation by organism of defense response of other organism involved in symbiotic interaction(GO:0052255) positive regulation by symbiont of host defense response(GO:0052509) positive regulation by organism of defense response of other organism involved in symbiotic interaction(GO:0052510) modulation by organism of immune response of other organism involved in symbiotic interaction(GO:0052552) modulation by symbiont of host immune response(GO:0052553) modulation by virus of host immune response(GO:0075528)
0.1	0.2	GO:0035508	positive regulation of myosin-light-chain-phosphatase activity(GO:0035508)
0.1	0.5	GO:0035426	extracellular matrix-cell signaling(GO:0035426)
0.1	0.3	GO:0072255	metanephric glomerular mesangial cell development(GO:0072255) reversible differentiation(GO:0090677) cell dedifferentiation involved in phenotypic switching(GO:0090678) positive regulation of phenotypic switching(GO:1900241) regulation of vascular smooth muscle cell dedifferentiation(GO:1905174) positive regulation of vascular smooth muscle cell dedifferentiation(GO:1905176) vascular smooth muscle cell dedifferentiation(GO:1990936)
0.1	0.3	GO:0061073	ciliary body morphogenesis(GO:0061073)
0.1	0.4	GO:0002296	T-helper 1 cell lineage commitment(GO:0002296)
0.1	0.2	GO:0071109	superior temporal gyrus development(GO:0071109)
0.1	0.5	GO:1900042	positive regulation of interleukin-2 secretion(GO:1900042)
0.1	0.3	GO:0051796	regulation of monophenol monooxygenase activity(GO:0032771) positive regulation of monophenol monooxygenase activity(GO:0032773) negative regulation of catagen(GO:0051796) regulation of hair cycle by canonical Wnt signaling pathway(GO:0060901) positive regulation of melanosome transport(GO:1902910)
0.1	0.5	GO:0061086	negative regulation of histone H3-K27 methylation(GO:0061086)
0.1	0.3	GO:0046379	extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379)
0.1	0.3	GO:0010593	negative regulation of lamellipodium assembly(GO:0010593)
0.1	0.8	GO:0010724	regulation of definitive erythrocyte differentiation(GO:0010724)
0.1	0.4	GO:0008626	granzyme-mediated apoptotic signaling pathway(GO:0008626)
0.1	0.2	GO:1902559	3'-phosphoadenosine 5'-phosphosulfate transport(GO:0046963) 3'-phospho-5'-adenylyl sulfate transmembrane transport(GO:1902559)
0.1	0.8	GO:1901525	negative regulation of macromitophagy(GO:1901525)
0.1	0.2	GO:0007388	anterior compartment pattern formation(GO:0007387) posterior compartment specification(GO:0007388)
0.1	0.4	GO:0097676	histone H3-K36 dimethylation(GO:0097676)
0.1	0.2	GO:1900186	negative regulation of clathrin-mediated endocytosis(GO:1900186)
0.1	0.4	GO:1900425	negative regulation of defense response to bacterium(GO:1900425)
0.1	0.3	GO:0035905	ascending aorta development(GO:0035905) ascending aorta morphogenesis(GO:0035910)
0.1	0.2	GO:0048627	myoblast development(GO:0048627)
0.1	0.2	GO:0061193	sensory organ boundary specification(GO:0008052) formation of organ boundary(GO:0010160) taste bud development(GO:0061193)
0.1	0.3	GO:0097252	oligodendrocyte apoptotic process(GO:0097252)
0.1	0.8	GO:0060056	mammary gland involution(GO:0060056)
0.1	0.6	GO:1902952	positive regulation of dendritic spine maintenance(GO:1902952) regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903756) negative regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903758)
0.1	0.5	GO:0045716	positive regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045716)
0.1	0.5	GO:0033484	nitric oxide homeostasis(GO:0033484)
0.1	0.3	GO:1990927	vesicle-mediated cholesterol transport(GO:0090119) calcium ion regulated lysosome exocytosis(GO:1990927)
0.1	1.5	GO:0034063	stress granule assembly(GO:0034063)
0.1	0.7	GO:1904379	protein localization to cytosolic proteasome complex(GO:1904327) protein localization to cytosolic proteasome complex involved in ERAD pathway(GO:1904379)
0.1	0.3	GO:0072086	specification of loop of Henle identity(GO:0072086)
0.1	0.6	GO:0035583	sequestering of TGFbeta in extracellular matrix(GO:0035583)
0.1	0.7	GO:2000270	negative regulation of fibroblast apoptotic process(GO:2000270)
0.1	0.2	GO:1901491	negative regulation of lymphangiogenesis(GO:1901491)
0.1	0.3	GO:0061015	snRNA import into nucleus(GO:0061015)
0.1	0.2	GO:0071879	positive regulation of adrenergic receptor signaling pathway(GO:0071879) retrograde trans-synaptic signaling by soluble gas(GO:0098923) trans-synaptic signaling by soluble gas(GO:0099543)
0.1	1.7	GO:0070816	phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.1	0.9	GO:1902902	negative regulation of autophagosome assembly(GO:1902902)
0.1	1.6	GO:0071481	cellular response to X-ray(GO:0071481)
0.1	0.4	GO:0051012	microtubule sliding(GO:0051012)
0.1	0.2	GO:0002904	positive regulation of B cell apoptotic process(GO:0002904)
0.1	0.2	GO:1903595	positive regulation of histamine secretion by mast cell(GO:1903595)
0.1	0.6	GO:0048050	post-embryonic eye morphogenesis(GO:0048050)
0.1	0.2	GO:0006422	aspartyl-tRNA aminoacylation(GO:0006422)
0.1	0.2	GO:1903028	positive regulation of opsonization(GO:1903028)
0.1	0.4	GO:1902231	positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.1	0.2	GO:1905044	Schwann cell proliferation involved in axon regeneration(GO:0014011) negative regulation of Schwann cell migration(GO:1900148) regulation of Schwann cell proliferation involved in axon regeneration(GO:1905044) negative regulation of Schwann cell proliferation involved in axon regeneration(GO:1905045)
0.1	0.5	GO:0090038	negative regulation of protein kinase C signaling(GO:0090038)
0.1	0.8	GO:0002051	osteoblast fate commitment(GO:0002051)
0.1	0.1	GO:1900147	Schwann cell migration(GO:0036135) regulation of Schwann cell migration(GO:1900147)
0.1	1.0	GO:0046325	negative regulation of glucose import(GO:0046325)
0.1	0.1	GO:1901097	negative regulation of autophagosome maturation(GO:1901097)
0.1	1.0	GO:0061302	smooth muscle cell-matrix adhesion(GO:0061302)
0.1	0.6	GO:0071847	TNFSF11-mediated signaling pathway(GO:0071847)
0.1	1.1	GO:0016540	protein autoprocessing(GO:0016540)
0.1	0.1	GO:0032289	central nervous system myelin formation(GO:0032289)
0.1	0.3	GO:0071543	diadenosine polyphosphate catabolic process(GO:0015961) diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.1	0.3	GO:0031291	Ran protein signal transduction(GO:0031291)
0.1	0.9	GO:0030949	positive regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030949)
0.1	0.3	GO:1903613	regulation of protein tyrosine phosphatase activity(GO:1903613) positive regulation of protein tyrosine phosphatase activity(GO:1903615)
0.1	0.3	GO:0036079	GDP-fucose transport(GO:0015783) purine nucleotide-sugar transport(GO:0036079)
0.1	0.3	GO:0093001	glycolysis from storage polysaccharide through glucose-1-phosphate(GO:0093001)
0.1	0.4	GO:0031584	activation of phospholipase D activity(GO:0031584)
0.1	0.7	GO:0010839	negative regulation of keratinocyte proliferation(GO:0010839)
0.1	1.2	GO:0000183	chromatin silencing at rDNA(GO:0000183)
0.1	0.2	GO:0032877	positive regulation of DNA endoreduplication(GO:0032877) negative regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0071930)
0.1	0.2	GO:0036166	phenotypic switching(GO:0036166) regulation of phenotypic switching(GO:1900239)
0.1	0.2	GO:0060489	orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490)
0.1	0.4	GO:0061502	early endosome to recycling endosome transport(GO:0061502)
0.1	0.2	GO:0001994	norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure(GO:0001994)
0.0	0.3	GO:0036438	maintenance of lens transparency(GO:0036438)
0.0	0.1	GO:0086044	atrial ventricular junction remodeling(GO:0003294) atrial cardiac muscle cell to AV node cell communication by electrical coupling(GO:0086044) bundle of His cell to Purkinje myocyte communication by electrical coupling(GO:0086054) Purkinje myocyte to ventricular cardiac muscle cell communication by electrical coupling(GO:0086055) regulation of Purkinje myocyte action potential(GO:0098906) vasomotion(GO:1990029)
0.0	0.4	GO:0030579	ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.0	0.3	GO:0070358	actin polymerization-dependent cell motility(GO:0070358)
0.0	0.3	GO:0060005	vestibular reflex(GO:0060005)
0.0	0.5	GO:0070970	interleukin-2 secretion(GO:0070970)
0.0	0.4	GO:0019255	glucose 1-phosphate metabolic process(GO:0019255)
0.0	0.2	GO:2000669	negative regulation of dendritic cell apoptotic process(GO:2000669)
0.0	0.8	GO:0032471	negative regulation of endoplasmic reticulum calcium ion concentration(GO:0032471)
0.0	0.5	GO:0010606	positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.0	0.3	GO:0051549	positive regulation of keratinocyte migration(GO:0051549)
0.0	0.1	GO:0032470	positive regulation of endoplasmic reticulum calcium ion concentration(GO:0032470) calcium ion transport from cytosol to endoplasmic reticulum(GO:1903515)
0.0	0.7	GO:0008090	retrograde axonal transport(GO:0008090)
0.0	0.5	GO:0000056	ribosomal small subunit export from nucleus(GO:0000056)
0.0	0.1	GO:1901837	negative regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901837)
0.0	0.1	GO:1903691	positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
0.0	0.2	GO:1902963	regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963)
0.0	0.5	GO:0015712	hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.0	3.4	GO:0010507	negative regulation of autophagy(GO:0010507)
0.0	0.3	GO:0014004	microglia differentiation(GO:0014004) microglia development(GO:0014005)
0.0	0.1	GO:0015881	creatine transport(GO:0015881) creatine transmembrane transport(GO:1902598)
0.0	0.1	GO:0046349	UDP-N-acetylglucosamine biosynthetic process(GO:0006048) amino sugar biosynthetic process(GO:0046349)
0.0	0.2	GO:0048861	leukemia inhibitory factor signaling pathway(GO:0048861)
0.0	0.3	GO:0097048	dendritic cell apoptotic process(GO:0097048) regulation of dendritic cell apoptotic process(GO:2000668) positive regulation of dendritic cell apoptotic process(GO:2000670)
0.0	0.2	GO:0051754	meiotic sister chromatid cohesion, centromeric(GO:0051754)
0.0	0.6	GO:0006610	ribosomal protein import into nucleus(GO:0006610)
0.0	0.0	GO:0002192	IRES-dependent translational initiation(GO:0002192)
0.0	0.1	GO:0048075	positive regulation of eye pigmentation(GO:0048075)
0.0	0.2	GO:0070885	negative regulation of calcineurin-NFAT signaling cascade(GO:0070885)
0.0	0.2	GO:0035063	nuclear speck organization(GO:0035063)
0.0	0.2	GO:0098582	innate vocalization behavior(GO:0098582)
0.0	0.3	GO:0071486	cellular response to high light intensity(GO:0071486) retinal rod cell apoptotic process(GO:0097473)
0.0	0.2	GO:0072674	multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675)
0.0	0.5	GO:0048298	positive regulation of isotype switching to IgA isotypes(GO:0048298)
0.0	0.2	GO:0043353	enucleate erythrocyte differentiation(GO:0043353)
0.0	0.5	GO:0051918	negative regulation of fibrinolysis(GO:0051918)
0.0	0.2	GO:1900748	positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.0	0.2	GO:0060399	positive regulation of growth hormone receptor signaling pathway(GO:0060399)
0.0	1.2	GO:0043651	linoleic acid metabolic process(GO:0043651)
0.0	0.9	GO:0007175	negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.0	0.2	GO:0033601	positive regulation of mammary gland epithelial cell proliferation(GO:0033601)
0.0	0.3	GO:0019075	virus maturation(GO:0019075)
0.0	0.1	GO:0090472	viral protein processing(GO:0019082) regulation of nerve growth factor production(GO:0032903) negative regulation of nerve growth factor production(GO:0032904) dibasic protein processing(GO:0090472)
0.0	0.0	GO:0003245	cardiac muscle tissue growth involved in heart morphogenesis(GO:0003245)
0.0	0.2	GO:0071897	DNA biosynthetic process(GO:0071897)
0.0	0.1	GO:1903225	negative regulation of endodermal cell differentiation(GO:1903225)
0.0	0.3	GO:0010989	negative regulation of low-density lipoprotein particle clearance(GO:0010989)
0.0	0.7	GO:2000675	negative regulation of type B pancreatic cell apoptotic process(GO:2000675)
0.0	1.1	GO:0016246	RNA interference(GO:0016246)
0.0	0.8	GO:0097062	dendritic spine maintenance(GO:0097062)
0.0	0.1	GO:0045875	negative regulation of sister chromatid cohesion(GO:0045875)
0.0	1.0	GO:0000185	activation of MAPKKK activity(GO:0000185)
0.0	0.2	GO:2000676	positive regulation of type B pancreatic cell apoptotic process(GO:2000676)
0.0	0.3	GO:0070601	centromeric sister chromatid cohesion(GO:0070601)
0.0	0.1	GO:1903450	regulation of G1 to G0 transition(GO:1903450) positive regulation of G1 to G0 transition(GO:1903452)
0.0	0.2	GO:0003433	chondrocyte development involved in endochondral bone morphogenesis(GO:0003433)
0.0	0.1	GO:0045743	positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.0	0.2	GO:1904448	negative regulation of gamma-aminobutyric acid secretion(GO:0014053) aspartate secretion(GO:0061528) positive regulation of prolactin secretion(GO:1902722) regulation of aspartate secretion(GO:1904448) positive regulation of aspartate secretion(GO:1904450)
0.0	0.2	GO:0097327	response to antineoplastic agent(GO:0097327) negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.0	0.5	GO:0015871	choline transport(GO:0015871)
0.0	0.1	GO:0003415	chondrocyte hypertrophy(GO:0003415)
0.0	0.3	GO:1990834	response to odorant(GO:1990834)
0.0	0.5	GO:0010499	proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.0	0.6	GO:0090168	Golgi reassembly(GO:0090168)
0.0	0.2	GO:0019087	transformation of host cell by virus(GO:0019087)
0.0	0.3	GO:1904352	positive regulation of protein catabolic process in the vacuole(GO:1904352)
0.0	0.9	GO:0006337	nucleosome disassembly(GO:0006337)
0.0	0.4	GO:0035331	negative regulation of hippo signaling(GO:0035331)
0.0	0.1	GO:0001672	regulation of chromatin assembly or disassembly(GO:0001672)
0.0	0.1	GO:0002384	hepatic immune response(GO:0002384)
0.0	0.2	GO:0048842	positive regulation of axon extension involved in axon guidance(GO:0048842)
0.0	0.5	GO:0031507	heterochromatin assembly(GO:0031507)
0.0	0.1	GO:0016321	female meiosis chromosome segregation(GO:0016321)
0.0	0.4	GO:0033299	secretion of lysosomal enzymes(GO:0033299)
0.0	0.5	GO:0000712	resolution of meiotic recombination intermediates(GO:0000712)
0.0	0.3	GO:0048102	autophagic cell death(GO:0048102)
0.0	0.5	GO:0006600	creatine metabolic process(GO:0006600)
0.0	0.1	GO:0072385	minus-end-directed organelle transport along microtubule(GO:0072385)
0.0	0.1	GO:1902811	tongue muscle cell differentiation(GO:0035981) positive regulation of skeletal muscle fiber differentiation(GO:1902811) regulation of tongue muscle cell differentiation(GO:2001035) positive regulation of tongue muscle cell differentiation(GO:2001037)
0.0	0.4	GO:0070327	thyroid hormone transport(GO:0070327)
0.0	0.1	GO:1904117	response to vasopressin(GO:1904116) cellular response to vasopressin(GO:1904117)
0.0	0.7	GO:0061436	establishment of skin barrier(GO:0061436)
0.0	0.2	GO:0086073	bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073)
0.0	0.1	GO:0019065	receptor-mediated endocytosis of virus by host cell(GO:0019065) endocytosis involved in viral entry into host cell(GO:0075509)
0.0	0.2	GO:0006868	glutamine transport(GO:0006868) L-cystine transport(GO:0015811)
0.0	0.7	GO:0035563	positive regulation of chromatin binding(GO:0035563)
0.0	0.3	GO:0060413	atrial septum morphogenesis(GO:0060413)
0.0	0.4	GO:1904354	negative regulation of telomere capping(GO:1904354)
0.0	0.2	GO:0001920	negative regulation of receptor recycling(GO:0001920)
0.0	0.1	GO:0044537	regulation of circulating fibrinogen levels(GO:0044537)
0.0	0.1	GO:0000415	negative regulation of histone H3-K36 methylation(GO:0000415)
0.0	0.2	GO:2000052	positive regulation of non-canonical Wnt signaling pathway(GO:2000052)
0.0	0.2	GO:0090063	positive regulation of microtubule nucleation(GO:0090063)
0.0	0.5	GO:0033623	regulation of integrin activation(GO:0033623)
0.0	0.6	GO:1903830	magnesium ion transmembrane transport(GO:1903830)
0.0	1.0	GO:0031581	hemidesmosome assembly(GO:0031581)
0.0	0.2	GO:2000582	positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.0	0.4	GO:0048341	paraxial mesoderm formation(GO:0048341)
0.0	0.2	GO:0070164	negative regulation of adiponectin secretion(GO:0070164)
0.0	0.2	GO:0043569	negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.0	0.1	GO:0001560	regulation of cell growth by extracellular stimulus(GO:0001560)
0.0	0.1	GO:0086021	SA node cell to atrial cardiac muscle cell communication by electrical coupling(GO:0086021)
0.0	0.1	GO:0010643	cell communication by chemical coupling(GO:0010643)
0.0	0.3	GO:0021759	globus pallidus development(GO:0021759)
0.0	0.2	GO:0002329	pre-B cell differentiation(GO:0002329)
0.0	0.6	GO:0046341	CDP-diacylglycerol metabolic process(GO:0046341)
0.0	0.1	GO:0021836	cerebral cortex tangential migration using cell-cell interactions(GO:0021823) postnatal olfactory bulb interneuron migration(GO:0021827) chemorepulsion involved in postnatal olfactory bulb interneuron migration(GO:0021836)
0.0	0.2	GO:0046985	positive regulation of hemoglobin biosynthetic process(GO:0046985)
0.0	0.2	GO:1901509	regulation of endothelial tube morphogenesis(GO:1901509)
0.0	0.8	GO:0046628	positive regulation of insulin receptor signaling pathway(GO:0046628)
0.0	0.4	GO:0019388	galactose catabolic process(GO:0019388)
0.0	0.1	GO:0043634	polyadenylation-dependent ncRNA catabolic process(GO:0043634)
0.0	0.1	GO:0035425	autocrine signaling(GO:0035425)
0.0	0.2	GO:2000795	negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.0	0.8	GO:0010832	negative regulation of myotube differentiation(GO:0010832)
0.0	0.1	GO:0071670	smooth muscle cell chemotaxis(GO:0071670)
0.0	0.6	GO:0014741	negative regulation of cardiac muscle hypertrophy(GO:0010614) negative regulation of muscle hypertrophy(GO:0014741)
0.0	0.1	GO:1902617	response to fluoride(GO:1902617)
0.0	0.1	GO:0021691	cerebellar Purkinje cell layer maturation(GO:0021691)
0.0	0.5	GO:0008340	determination of adult lifespan(GO:0008340)
0.0	0.2	GO:0031116	positive regulation of microtubule polymerization(GO:0031116)
0.0	0.2	GO:0070444	oligodendrocyte progenitor proliferation(GO:0070444) regulation of oligodendrocyte progenitor proliferation(GO:0070445)
0.0	0.6	GO:0007172	signal complex assembly(GO:0007172)
0.0	0.4	GO:0042759	long-chain fatty acid biosynthetic process(GO:0042759)
0.0	0.2	GO:0030578	PML body organization(GO:0030578)
0.0	0.0	GO:1901978	positive regulation of cell cycle checkpoint(GO:1901978)
0.0	0.1	GO:2000234	positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
0.0	0.7	GO:0031954	positive regulation of protein autophosphorylation(GO:0031954)
0.0	0.1	GO:0007256	activation of JNKK activity(GO:0007256)
0.0	0.4	GO:0038203	TORC2 signaling(GO:0038203)
0.0	0.1	GO:0001543	ovarian follicle rupture(GO:0001543)
0.0	0.5	GO:1904778	regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.0	0.2	GO:0018344	protein geranylgeranylation(GO:0018344)
0.0	0.2	GO:0010452	regulation of histone H3-K36 methylation(GO:0000414) histone H3-K36 methylation(GO:0010452)
0.0	0.7	GO:0051764	actin crosslink formation(GO:0051764)
0.0	0.3	GO:0015684	ferrous iron transport(GO:0015684) ferrous iron transmembrane transport(GO:1903874)
0.0	0.0	GO:0032915	positive regulation of transforming growth factor beta2 production(GO:0032915)
0.0	0.1	GO:0035105	sterol regulatory element binding protein import into nucleus(GO:0035105)
0.0	0.1	GO:2000323	negative regulation of glucocorticoid receptor signaling pathway(GO:2000323)
0.0	0.3	GO:0016127	cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.0	0.2	GO:0070914	UV-damage excision repair(GO:0070914)
0.0	0.4	GO:0075522	IRES-dependent viral translational initiation(GO:0075522)
0.0	0.0	GO:0033364	mast cell secretory granule organization(GO:0033364)
0.0	0.2	GO:0043622	cortical microtubule organization(GO:0043622) establishment of centrosome localization(GO:0051660)
0.0	0.1	GO:0097010	eukaryotic translation initiation factor 4F complex assembly(GO:0097010)
0.0	0.2	GO:0048642	negative regulation of skeletal muscle tissue development(GO:0048642)
0.0	0.3	GO:0007084	mitotic nuclear envelope reassembly(GO:0007084)
0.0	0.1	GO:0001768	establishment of T cell polarity(GO:0001768)
0.0	0.1	GO:0051684	maintenance of Golgi location(GO:0051684)
0.0	0.2	GO:0010792	DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792)
0.0	0.1	GO:0040009	regulation of growth rate(GO:0040009)
0.0	0.2	GO:0006002	fructose 6-phosphate metabolic process(GO:0006002)
0.0	0.1	GO:0070940	dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.0	0.2	GO:0099563	modification of synaptic structure(GO:0099563)
0.0	0.2	GO:0030502	negative regulation of bone mineralization(GO:0030502)
0.0	0.3	GO:0018206	peptidyl-methionine modification(GO:0018206)
0.0	0.0	GO:0010159	specification of organ position(GO:0010159)
0.0	0.3	GO:0006662	glycerol ether metabolic process(GO:0006662)
0.0	0.6	GO:0000717	nucleotide-excision repair, DNA duplex unwinding(GO:0000717)
0.0	0.1	GO:0033031	positive regulation of neutrophil apoptotic process(GO:0033031)
0.0	0.1	GO:0021943	formation of radial glial scaffolds(GO:0021943)
0.0	0.3	GO:0090312	positive regulation of protein deacetylation(GO:0090312)
0.0	0.2	GO:0035635	entry of bacterium into host cell(GO:0035635)
0.0	0.1	GO:2001288	positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.0	0.2	GO:1901725	regulation of histone deacetylase activity(GO:1901725)
0.0	0.1	GO:0060743	epithelial cell maturation involved in prostate gland development(GO:0060743)
0.0	0.3	GO:0048681	negative regulation of axon regeneration(GO:0048681)
0.0	0.2	GO:2000622	regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.0	0.2	GO:0007512	adult heart development(GO:0007512)
0.0	0.1	GO:2001270	regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001270) negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.0	0.3	GO:0010801	negative regulation of peptidyl-threonine phosphorylation(GO:0010801)
0.0	0.1	GO:0001544	initiation of primordial ovarian follicle growth(GO:0001544)
0.0	0.1	GO:0000379	tRNA-type intron splice site recognition and cleavage(GO:0000379)
0.0	0.1	GO:1904694	negative regulation of vascular smooth muscle contraction(GO:1904694)
0.0	0.1	GO:0033489	cholesterol biosynthetic process via desmosterol(GO:0033489) cholesterol biosynthetic process via lathosterol(GO:0033490)
0.0	0.5	GO:0043555	regulation of translation in response to stress(GO:0043555)
0.0	0.3	GO:2000059	negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:2000059)
0.0	0.1	GO:1902714	negative regulation of interferon-gamma secretion(GO:1902714)
0.0	0.1	GO:0097498	endothelial tube lumen extension(GO:0097498)
0.0	0.2	GO:0090557	establishment of endothelial intestinal barrier(GO:0090557)
0.0	0.0	GO:0036388	pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
0.0	0.5	GO:1902857	positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.0	0.4	GO:0030277	maintenance of gastrointestinal epithelium(GO:0030277)
0.0	1.1	GO:0006446	regulation of translational initiation(GO:0006446)
0.0	0.1	GO:0021891	olfactory bulb interneuron development(GO:0021891)
0.0	0.1	GO:0032815	negative regulation of natural killer cell activation(GO:0032815)
0.0	0.1	GO:0006449	regulation of translational termination(GO:0006449)
0.0	0.1	GO:0036228	protein targeting to nuclear inner membrane(GO:0036228)
0.0	0.3	GO:0051292	nuclear pore complex assembly(GO:0051292)
0.0	0.0	GO:0090235	regulation of metaphase plate congression(GO:0090235)
0.0	0.0	GO:1903060	regulation of N-terminal protein palmitoylation(GO:0060254) negative regulation of N-terminal protein palmitoylation(GO:0060262) negative regulation of protein lipidation(GO:1903060)
0.0	1.1	GO:0050909	sensory perception of taste(GO:0050909)
0.0	0.2	GO:0007168	receptor guanylyl cyclase signaling pathway(GO:0007168)
0.0	0.1	GO:0038065	collagen-activated signaling pathway(GO:0038065)
0.0	0.6	GO:0046825	regulation of protein export from nucleus(GO:0046825)
0.0	0.2	GO:0045040	protein import into mitochondrial outer membrane(GO:0045040)
0.0	0.8	GO:0032508	DNA duplex unwinding(GO:0032508)
0.0	0.1	GO:0000707	meiotic DNA recombinase assembly(GO:0000707)
0.0	0.4	GO:1902036	regulation of hematopoietic stem cell differentiation(GO:1902036)
0.0	1.7	GO:0030838	positive regulation of actin filament polymerization(GO:0030838)
0.0	0.2	GO:0070830	bicellular tight junction assembly(GO:0070830)
0.0	0.0	GO:0035995	detection of muscle stretch(GO:0035995)
0.0	0.3	GO:0043981	histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
0.0	0.4	GO:0090527	actin filament reorganization(GO:0090527)
0.0	0.1	GO:0075071	autophagy of host cells involved in interaction with symbiont(GO:0075044) autophagy involved in symbiotic interaction(GO:0075071)
0.0	0.2	GO:0002158	osteoclast proliferation(GO:0002158)
0.0	0.4	GO:0035855	megakaryocyte development(GO:0035855)
0.0	0.8	GO:0045453	bone resorption(GO:0045453)
0.0	0.4	GO:0071425	hematopoietic stem cell proliferation(GO:0071425)
0.0	0.4	GO:0090162	establishment of epithelial cell polarity(GO:0090162)
0.0	0.2	GO:1904259	regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904259) positive regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904261) basement membrane assembly involved in embryonic body morphogenesis(GO:2001197)
0.0	0.3	GO:0003085	negative regulation of systemic arterial blood pressure(GO:0003085)
0.0	0.2	GO:0005981	regulation of glycogen catabolic process(GO:0005981)
0.0	0.3	GO:1901897	regulation of relaxation of cardiac muscle(GO:1901897)
0.0	0.1	GO:0070836	caveola assembly(GO:0070836)
0.0	0.2	GO:0097150	neuronal stem cell population maintenance(GO:0097150)
0.0	0.0	GO:0072053	renal inner medulla development(GO:0072053) renal outer medulla development(GO:0072054)
0.0	0.1	GO:0035562	negative regulation of chromatin binding(GO:0035562)
0.0	0.1	GO:0034351	regulation of glial cell apoptotic process(GO:0034350) negative regulation of glial cell apoptotic process(GO:0034351)
0.0	0.4	GO:0036065	fucosylation(GO:0036065)
0.0	0.1	GO:0097012	cellular response to granulocyte macrophage colony-stimulating factor stimulus(GO:0097011) response to granulocyte macrophage colony-stimulating factor(GO:0097012)
0.0	0.1	GO:0006933	negative regulation of cell adhesion involved in substrate-bound cell migration(GO:0006933)
0.0	0.2	GO:0045063	T-helper 1 cell differentiation(GO:0045063)
0.0	0.2	GO:0006054	N-acetylneuraminate metabolic process(GO:0006054)
0.0	0.1	GO:0051798	positive regulation of hair cycle(GO:0042635) positive regulation of hair follicle development(GO:0051798)
0.0	0.1	GO:0009650	UV protection(GO:0009650)
0.0	0.1	GO:0044829	positive regulation by host of viral genome replication(GO:0044829)
0.0	1.4	GO:0001578	microtubule bundle formation(GO:0001578)
0.0	0.1	GO:0033615	mitochondrial proton-transporting ATP synthase complex assembly(GO:0033615)
0.0	0.1	GO:0090309	positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.0	0.0	GO:0001777	T cell homeostatic proliferation(GO:0001777)
0.0	0.2	GO:0007095	mitotic G2 DNA damage checkpoint(GO:0007095)
0.0	2.2	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0	0.2	GO:0006412	translation(GO:0006412)
0.0	0.2	GO:0006020	inositol metabolic process(GO:0006020)
0.0	0.1	GO:0003366	cell-matrix adhesion involved in ameboidal cell migration(GO:0003366)
0.0	0.2	GO:2001237	negative regulation of extrinsic apoptotic signaling pathway(GO:2001237)
0.0	0.2	GO:0007220	Notch receptor processing(GO:0007220)

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	1.2	GO:0002944	cyclin K-CDK12 complex(GO:0002944)
0.3	2.2	GO:0097129	cyclin D2-CDK4 complex(GO:0097129)
0.2	0.7	GO:0097489	multivesicular body, internal vesicle lumen(GO:0097489)
0.2	0.7	GO:0097444	spine apparatus(GO:0097444)
0.2	0.7	GO:0043511	inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.2	1.5	GO:0033553	rDNA heterochromatin(GO:0033553)
0.2	1.4	GO:0097209	epidermal lamellar body(GO:0097209)
0.2	0.2	GO:0034681	integrin alpha11-beta1 complex(GO:0034681)
0.2	0.9	GO:0071942	XPC complex(GO:0071942)
0.2	0.2	GO:0032593	insulin-responsive compartment(GO:0032593)
0.2	2.3	GO:0097197	tetraspanin-enriched microdomain(GO:0097197)
0.2	0.5	GO:1990032	parallel fiber(GO:1990032)
0.1	0.6	GO:0034667	integrin alpha3-beta1 complex(GO:0034667)
0.1	0.8	GO:0030121	AP-1 adaptor complex(GO:0030121)
0.1	0.3	GO:1990666	PCSK9-LDLR complex(GO:1990666)
0.1	0.5	GO:1990851	Wnt-Frizzled-LRP5/6 complex(GO:1990851)
0.1	0.3	GO:0034678	integrin alpha8-beta1 complex(GO:0034678)
0.1	0.3	GO:0036117	hyaluranon cable(GO:0036117)
0.1	0.8	GO:0097452	GAIT complex(GO:0097452)
0.1	2.6	GO:0016281	eukaryotic translation initiation factor 4F complex(GO:0016281)
0.1	1.4	GO:0001520	outer dense fiber(GO:0001520)
0.1	0.9	GO:0005955	calcineurin complex(GO:0005955)
0.1	0.8	GO:0046696	lipopolysaccharide receptor complex(GO:0046696)
0.1	0.3	GO:0071665	gamma-catenin-TCF7L2 complex(GO:0071665)
0.1	0.5	GO:0031673	H zone(GO:0031673)
0.1	2.3	GO:0071564	npBAF complex(GO:0071564)
0.1	0.7	GO:0005587	collagen type IV trimer(GO:0005587)
0.1	0.3	GO:0031251	PAN complex(GO:0031251)
0.1	0.5	GO:0005899	insulin receptor complex(GO:0005899)
0.1	0.4	GO:0000333	telomerase catalytic core complex(GO:0000333)
0.1	0.3	GO:0071001	U4/U6 snRNP(GO:0071001)
0.1	0.5	GO:0005945	6-phosphofructokinase complex(GO:0005945)
0.1	1.5	GO:0005671	Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.1	0.5	GO:0005677	chromatin silencing complex(GO:0005677)
0.1	0.1	GO:0097422	tubular endosome(GO:0097422)
0.1	0.5	GO:0032437	cuticular plate(GO:0032437)
0.1	0.2	GO:0045160	myosin I complex(GO:0045160)
0.1	0.7	GO:0071818	BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.1	0.2	GO:0042585	germinal vesicle(GO:0042585)
0.1	0.7	GO:0070775	H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0	0.6	GO:0042788	polysomal ribosome(GO:0042788)
0.0	1.2	GO:0043194	axon initial segment(GO:0043194)
0.0	0.1	GO:0075341	host cell PML body(GO:0075341)
0.0	0.3	GO:0042825	TAP complex(GO:0042825)
0.0	0.3	GO:0070381	endosome to plasma membrane transport vesicle(GO:0070381)
0.0	0.3	GO:0031415	NatA complex(GO:0031415)
0.0	0.2	GO:0005968	Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.0	0.8	GO:0005652	nuclear lamina(GO:0005652)
0.0	0.8	GO:0090544	BAF-type complex(GO:0090544)
0.0	1.3	GO:0034706	sodium channel complex(GO:0034706)
0.0	0.2	GO:0072534	perineuronal net(GO:0072534)
0.0	0.4	GO:0000439	core TFIIH complex(GO:0000439)
0.0	0.1	GO:0005584	collagen type I trimer(GO:0005584)
0.0	0.2	GO:1990425	ryanodine receptor complex(GO:1990425)
0.0	0.2	GO:0060187	cell pole(GO:0060187)
0.0	0.1	GO:0005588	collagen type V trimer(GO:0005588)
0.0	0.1	GO:0031933	telomeric heterochromatin(GO:0031933)
0.0	0.6	GO:0031209	SCAR complex(GO:0031209)
0.0	0.2	GO:0032144	4-aminobutyrate transaminase complex(GO:0032144)
0.0	0.1	GO:0031084	BLOC-2 complex(GO:0031084)
0.0	0.1	GO:0070369	beta-catenin-TCF7L2 complex(GO:0070369)
0.0	0.1	GO:0032173	septin ring(GO:0005940) septin collar(GO:0032173)
0.0	1.6	GO:0000159	protein phosphatase type 2A complex(GO:0000159)
0.0	1.1	GO:0031105	septin complex(GO:0031105)
0.0	0.2	GO:0031417	NatC complex(GO:0031417)
0.0	1.1	GO:0031143	pseudopodium(GO:0031143)
0.0	1.5	GO:0044665	MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0	0.3	GO:0001940	male pronucleus(GO:0001940)
0.0	0.5	GO:0033391	chromatoid body(GO:0033391)
0.0	0.5	GO:0031080	nuclear pore outer ring(GO:0031080)
0.0	0.7	GO:0030877	beta-catenin destruction complex(GO:0030877)
0.0	0.1	GO:0031085	BLOC-3 complex(GO:0031085)
0.0	0.5	GO:0072357	PTW/PP1 phosphatase complex(GO:0072357)
0.0	0.4	GO:0030478	actin cap(GO:0030478)
0.0	1.2	GO:0032590	dendrite membrane(GO:0032590)
0.0	0.1	GO:0071008	U2-type post-mRNA release spliceosomal complex(GO:0071008)
0.0	0.8	GO:0030014	CCR4-NOT complex(GO:0030014)
0.0	0.1	GO:0071062	alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.0	0.1	GO:0005595	collagen type XII trimer(GO:0005595)
0.0	0.3	GO:0000124	SAGA complex(GO:0000124)
0.0	0.7	GO:0071011	precatalytic spliceosome(GO:0071011)
0.0	0.2	GO:0000942	condensed nuclear chromosome outer kinetochore(GO:0000942)
0.0	0.3	GO:0032584	growth cone membrane(GO:0032584)
0.0	0.1	GO:0005577	fibrinogen complex(GO:0005577)
0.0	0.7	GO:0071004	U2-type prespliceosome(GO:0071004)
0.0	0.1	GO:0005896	interleukin-6 receptor complex(GO:0005896)
0.0	1.0	GO:0030057	desmosome(GO:0030057)
0.0	0.1	GO:0097629	extrinsic component of omegasome membrane(GO:0097629)
0.0	0.4	GO:0005915	zonula adherens(GO:0005915)
0.0	0.6	GO:0043205	microfibril(GO:0001527) fibril(GO:0043205)
0.0	0.3	GO:0005642	annulate lamellae(GO:0005642)
0.0	0.3	GO:0032009	early phagosome(GO:0032009)
0.0	2.4	GO:0005637	nuclear inner membrane(GO:0005637)
0.0	0.2	GO:0071203	WASH complex(GO:0071203)
0.0	0.9	GO:0016581	NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0	0.7	GO:0030904	retromer complex(GO:0030904)
0.0	3.2	GO:0042641	actomyosin(GO:0042641)
0.0	0.4	GO:0000813	ESCRT I complex(GO:0000813)
0.0	0.1	GO:0008537	proteasome activator complex(GO:0008537)
0.0	2.7	GO:0005905	clathrin-coated pit(GO:0005905)
0.0	1.8	GO:0043198	dendritic shaft(GO:0043198)
0.0	0.7	GO:0016327	apicolateral plasma membrane(GO:0016327)
0.0	0.1	GO:0005916	fascia adherens(GO:0005916)
0.0	0.2	GO:0044354	pinosome(GO:0044352) macropinosome(GO:0044354)
0.0	1.5	GO:0035097	histone methyltransferase complex(GO:0035097)
0.0	0.7	GO:0005697	telomerase holoenzyme complex(GO:0005697)
0.0	0.5	GO:0035145	exon-exon junction complex(GO:0035145)
0.0	0.2	GO:0000164	protein phosphatase type 1 complex(GO:0000164)
0.0	0.1	GO:0048476	Holliday junction resolvase complex(GO:0048476)
0.0	1.1	GO:0001772	immunological synapse(GO:0001772)
0.0	0.1	GO:0097443	sorting endosome(GO:0097443)
0.0	0.4	GO:0034663	endoplasmic reticulum chaperone complex(GO:0034663)
0.0	0.2	GO:0032797	SMN complex(GO:0032797) SMN-Sm protein complex(GO:0034719)
0.0	0.1	GO:0070876	SOSS complex(GO:0070876)
0.0	0.1	GO:1990909	Wnt signalosome(GO:1990909)
0.0	0.1	GO:0033063	Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.0	0.2	GO:0005964	phosphorylase kinase complex(GO:0005964)
0.0	0.2	GO:0097470	ribbon synapse(GO:0097470)
0.0	0.1	GO:0005947	mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.0	0.0	GO:0072563	endothelial microparticle(GO:0072563)
0.0	0.7	GO:0000407	pre-autophagosomal structure(GO:0000407)
0.0	0.0	GO:0044609	DBIRD complex(GO:0044609)
0.0	0.1	GO:0031501	mannosyltransferase complex(GO:0031501)
0.0	0.1	GO:0033596	TSC1-TSC2 complex(GO:0033596)
0.0	0.1	GO:0044611	nuclear pore inner ring(GO:0044611)
0.0	0.4	GO:0031932	TORC2 complex(GO:0031932)
0.0	0.8	GO:0002102	podosome(GO:0002102)
0.0	0.3	GO:0030056	hemidesmosome(GO:0030056)
0.0	0.3	GO:0031089	platelet dense granule lumen(GO:0031089)
0.0	0.2	GO:0008091	spectrin(GO:0008091)
0.0	0.5	GO:0071782	endoplasmic reticulum tubular network(GO:0071782)
0.0	0.1	GO:0005827	polar microtubule(GO:0005827)
0.0	0.0	GO:0016589	NURF complex(GO:0016589)
0.0	0.1	GO:1990452	Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.0	0.2	GO:0034098	VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.0	0.1	GO:0000214	tRNA-intron endonuclease complex(GO:0000214)
0.0	1.9	GO:0005884	actin filament(GO:0005884)
0.0	0.1	GO:0016461	unconventional myosin complex(GO:0016461)
0.0	0.1	GO:0005791	rough endoplasmic reticulum(GO:0005791)
0.0	0.1	GO:0042406	extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.0	0.4	GO:0030867	rough endoplasmic reticulum membrane(GO:0030867)
0.0	0.7	GO:0032420	stereocilium(GO:0032420)
0.0	0.0	GO:0097135	cyclin E2-CDK2 complex(GO:0097135)
0.0	0.0	GO:0034455	t-UTP complex(GO:0034455)
0.0	0.1	GO:0000275	mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275)
0.0	0.9	GO:0005801	cis-Golgi network(GO:0005801)
0.0	0.2	GO:0097431	mitotic spindle pole(GO:0097431)
0.0	0.3	GO:0044232	organelle membrane contact site(GO:0044232)
0.0	0.4	GO:1990752	microtubule end(GO:1990752)
0.0	0.2	GO:0045180	basal cortex(GO:0045180)
0.0	0.1	GO:0010369	chromocenter(GO:0010369)
0.0	0.2	GO:0005744	mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.0	1.1	GO:0031093	platelet alpha granule lumen(GO:0031093)
0.0	0.1	GO:0035686	sperm fibrous sheath(GO:0035686)
0.0	0.1	GO:0034669	integrin alpha4-beta7 complex(GO:0034669)
0.0	0.2	GO:0005795	Golgi stack(GO:0005795)
0.0	0.2	GO:0071141	SMAD protein complex(GO:0071141)
0.0	0.2	GO:0033643	host cell part(GO:0033643)
0.0	0.1	GO:0031465	Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.5	1.5	GO:0016964	alpha-2 macroglobulin receptor activity(GO:0016964)
0.4	2.6	GO:0050119	N-acetylglucosamine deacetylase activity(GO:0050119)
0.3	1.4	GO:0005006	epidermal growth factor-activated receptor activity(GO:0005006)
0.2	0.9	GO:0004874	aryl hydrocarbon receptor activity(GO:0004874)
0.2	0.5	GO:1904928	coreceptor activity involved in canonical Wnt signaling pathway(GO:1904928)
0.2	0.5	GO:0005128	erythropoietin receptor binding(GO:0005128)
0.2	1.0	GO:0016213	linoleoyl-CoA desaturase activity(GO:0016213)
0.2	0.5	GO:0071633	dihydroceramidase activity(GO:0071633)
0.1	0.4	GO:0061505	DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.1	0.8	GO:0034186	apolipoprotein A-I binding(GO:0034186)
0.1	1.3	GO:0038049	transcription factor activity, ligand-activated RNA polymerase II transcription factor binding(GO:0038049)
0.1	0.3	GO:0036440	citrate (Si)-synthase activity(GO:0004108) citrate synthase activity(GO:0036440)
0.1	0.4	GO:0032184	SUMO polymer binding(GO:0032184)
0.1	2.3	GO:0008190	eukaryotic initiation factor 4E binding(GO:0008190)
0.1	4.1	GO:0016922	ligand-dependent nuclear receptor binding(GO:0016922)
0.1	0.3	GO:0035034	histone acetyltransferase regulator activity(GO:0035034)
0.1	0.3	GO:0005199	structural constituent of cell wall(GO:0005199)
0.1	0.3	GO:0036033	mediator complex binding(GO:0036033)
0.1	0.5	GO:0050436	microfibril binding(GO:0050436)
0.1	0.5	GO:0019828	aspartic-type endopeptidase inhibitor activity(GO:0019828)
0.1	0.3	GO:0070579	methylcytosine dioxygenase activity(GO:0070579)
0.1	0.3	GO:0015130	mevalonate transmembrane transporter activity(GO:0015130)
0.1	0.5	GO:0070699	type II activin receptor binding(GO:0070699)
0.1	0.6	GO:0042835	BRE binding(GO:0042835)
0.1	1.4	GO:0004723	calcium-dependent protein serine/threonine phosphatase activity(GO:0004723)
0.1	0.7	GO:0031730	CCR5 chemokine receptor binding(GO:0031730)
0.1	0.2	GO:0046964	3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity(GO:0046964)
0.1	3.7	GO:0046966	thyroid hormone receptor binding(GO:0046966)
0.1	1.8	GO:0008353	RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.1	0.1	GO:0048185	activin binding(GO:0048185)
0.1	1.1	GO:0097371	MDM2/MDM4 family protein binding(GO:0097371)
0.1	1.1	GO:0038064	collagen receptor activity(GO:0038064)
0.1	0.2	GO:0001226	RNA polymerase II transcription corepressor binding(GO:0001226)
0.1	1.2	GO:0015280	ligand-gated sodium channel activity(GO:0015280)
0.1	0.5	GO:0035662	Toll-like receptor 4 binding(GO:0035662)
0.1	0.5	GO:0015526	hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.1	0.3	GO:0001190	transcriptional activator activity, RNA polymerase II transcription factor binding(GO:0001190) transcriptional repressor activity, RNA polymerase II activating transcription factor binding(GO:0098811)
0.1	0.9	GO:0035374	chondroitin sulfate binding(GO:0035374)
0.1	0.4	GO:0004614	phosphoglucomutase activity(GO:0004614)
0.1	0.3	GO:0015433	peptide antigen-transporting ATPase activity(GO:0015433)
0.1	2.5	GO:0070530	K63-linked polyubiquitin binding(GO:0070530)
0.1	0.4	GO:0051748	UTP:glucose-1-phosphate uridylyltransferase activity(GO:0003983) UTP-monosaccharide-1-phosphate uridylyltransferase activity(GO:0051748)
0.1	0.5	GO:0071532	ankyrin repeat binding(GO:0071532)
0.1	0.3	GO:0050501	hyaluronan synthase activity(GO:0050501)
0.1	0.2	GO:0035035	histone acetyltransferase binding(GO:0035035)
0.1	0.3	GO:0010465	nerve growth factor receptor activity(GO:0010465)
0.1	0.3	GO:0033906	hyaluronoglucuronidase activity(GO:0033906)
0.1	0.5	GO:0046975	histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.1	0.5	GO:0043237	laminin-1 binding(GO:0043237)
0.1	0.2	GO:0003881	CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity(GO:0003881)
0.1	0.3	GO:0052844	endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432) inositol diphosphate tetrakisphosphate diphosphatase activity(GO:0052840) inositol bisdiphosphate tetrakisphosphate diphosphatase activity(GO:0052841) inositol diphosphate pentakisphosphate diphosphatase activity(GO:0052842) inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity(GO:0052843) inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity(GO:0052844) inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity(GO:0052845) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity(GO:0052846) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052847) inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052848)
0.1	1.4	GO:0070016	armadillo repeat domain binding(GO:0070016)
0.1	0.3	GO:0008113	peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.1	0.5	GO:0003872	6-phosphofructokinase activity(GO:0003872)
0.1	1.8	GO:0032041	histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.1	0.2	GO:0017130	poly(C) RNA binding(GO:0017130)
0.1	0.3	GO:0005457	GDP-fucose transmembrane transporter activity(GO:0005457) purine nucleotide-sugar transmembrane transporter activity(GO:0036080)
0.1	0.3	GO:0039552	RIG-I binding(GO:0039552)
0.1	0.9	GO:0004030	aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030)
0.1	0.2	GO:0005166	neurotrophin p75 receptor binding(GO:0005166)
0.1	0.3	GO:0050115	myosin-light-chain-phosphatase activity(GO:0050115)
0.1	0.9	GO:0016176	superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.1	0.3	GO:0097001	ceramide binding(GO:0097001)
0.0	0.4	GO:0004430	1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.0	0.1	GO:0086076	gap junction channel activity involved in atrial cardiac muscle cell-AV node cell electrical coupling(GO:0086076) gap junction channel activity involved in bundle of His cell-Purkinje myocyte electrical coupling(GO:0086078) gap junction channel activity involved in Purkinje myocyte-ventricular cardiac muscle cell electrical coupling(GO:0086079)
0.0	0.5	GO:0010859	calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.0	0.9	GO:0031852	mu-type opioid receptor binding(GO:0031852)
0.0	1.1	GO:0045294	alpha-catenin binding(GO:0045294)
0.0	0.5	GO:0004111	creatine kinase activity(GO:0004111)
0.0	0.3	GO:0043183	vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.0	3.3	GO:0001205	transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0	0.5	GO:0032050	clathrin heavy chain binding(GO:0032050)
0.0	0.1	GO:0086039	lutropin-choriogonadotropic hormone receptor binding(GO:0031775) calcium-transporting ATPase activity involved in regulation of cardiac muscle cell membrane potential(GO:0086039)
0.0	0.5	GO:0034235	GPI anchor binding(GO:0034235)
0.0	0.4	GO:0016941	natriuretic peptide receptor activity(GO:0016941)
0.0	1.0	GO:0008349	MAP kinase kinase kinase kinase activity(GO:0008349)
0.0	0.4	GO:1990829	C-rich single-stranded DNA binding(GO:1990829)
0.0	0.5	GO:0097157	pre-mRNA intronic binding(GO:0097157)
0.0	0.1	GO:0005010	insulin-like growth factor-activated receptor activity(GO:0005010)
0.0	0.6	GO:0003720	telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.0	0.4	GO:0043426	MRF binding(GO:0043426)
0.0	0.1	GO:0005308	creatine transmembrane transporter activity(GO:0005308)
0.0	0.1	GO:0070119	ciliary neurotrophic factor binding(GO:0070119)
0.0	0.1	GO:0003863	alpha-ketoacid dehydrogenase activity(GO:0003826) 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity(GO:0003863)
0.0	0.2	GO:0004815	aspartate-tRNA ligase activity(GO:0004815)
0.0	0.2	GO:0030197	extracellular matrix constituent, lubricant activity(GO:0030197)
0.0	0.2	GO:0015207	ATP:ADP antiporter activity(GO:0005471) adenine transmembrane transporter activity(GO:0015207)
0.0	0.3	GO:0047522	13-prostaglandin reductase activity(GO:0036132) 15-oxoprostaglandin 13-oxidase activity(GO:0047522)
0.0	0.4	GO:0015349	thyroid hormone transmembrane transporter activity(GO:0015349)
0.0	0.3	GO:0008109	N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.0	0.7	GO:0051864	histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0	0.4	GO:0045295	gamma-catenin binding(GO:0045295)
0.0	0.7	GO:0048156	tau protein binding(GO:0048156)
0.0	0.6	GO:0008517	folic acid transporter activity(GO:0008517)
0.0	0.2	GO:0004663	Rab geranylgeranyltransferase activity(GO:0004663)
0.0	1.6	GO:0031593	polyubiquitin binding(GO:0031593)
0.0	0.1	GO:0015616	DNA translocase activity(GO:0015616)
0.0	1.6	GO:0004198	calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0	0.2	GO:0003867	4-aminobutyrate transaminase activity(GO:0003867) succinate-semialdehyde dehydrogenase binding(GO:0032145) (S)-3-amino-2-methylpropionate transaminase activity(GO:0047298)
0.0	0.2	GO:0045118	azole transporter activity(GO:0045118)
0.0	0.3	GO:0030621	U4 snRNA binding(GO:0030621)
0.0	0.3	GO:0005078	MAP-kinase scaffold activity(GO:0005078)
0.0	0.1	GO:0045322	unmethylated CpG binding(GO:0045322)
0.0	0.2	GO:0004517	nitric-oxide synthase activity(GO:0004517)
0.0	0.8	GO:0034450	ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0	0.1	GO:0098640	integrin binding involved in cell-matrix adhesion(GO:0098640)
0.0	0.7	GO:0046965	retinoid X receptor binding(GO:0046965)
0.0	0.2	GO:0004936	alpha-adrenergic receptor activity(GO:0004936)
0.0	0.2	GO:0005134	interleukin-2 receptor binding(GO:0005134)
0.0	0.1	GO:0048257	3'-flap endonuclease activity(GO:0048257)
0.0	1.1	GO:0070064	proline-rich region binding(GO:0070064)
0.0	0.2	GO:0086083	cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.0	0.2	GO:0015186	L-cystine transmembrane transporter activity(GO:0015184) L-glutamine transmembrane transporter activity(GO:0015186)
0.0	0.3	GO:0046920	alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.0	0.7	GO:0004065	arylsulfatase activity(GO:0004065)
0.0	0.5	GO:0004596	peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0	0.1	GO:0004706	JUN kinase kinase kinase activity(GO:0004706)
0.0	0.2	GO:0048407	platelet-derived growth factor binding(GO:0048407)
0.0	0.1	GO:0008267	poly-glutamine tract binding(GO:0008267)
0.0	0.6	GO:0015095	magnesium ion transmembrane transporter activity(GO:0015095)
0.0	0.7	GO:0017160	Ral GTPase binding(GO:0017160)
0.0	1.4	GO:0005080	protein kinase C binding(GO:0005080)
0.0	0.6	GO:0043522	leucine zipper domain binding(GO:0043522)
0.0	0.3	GO:0017162	aryl hydrocarbon receptor binding(GO:0017162)
0.0	0.2	GO:0042030	ATPase inhibitor activity(GO:0042030)
0.0	0.3	GO:0008420	CTD phosphatase activity(GO:0008420)
0.0	0.2	GO:0033857	diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.0	0.1	GO:0086020	gap junction channel activity involved in SA node cell-atrial cardiac muscle cell electrical coupling(GO:0086020)
0.0	0.2	GO:0004563	beta-N-acetylhexosaminidase activity(GO:0004563)
0.0	0.3	GO:0042731	PH domain binding(GO:0042731)
0.0	0.5	GO:0017034	Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0	0.4	GO:0005049	nuclear export signal receptor activity(GO:0005049)
0.0	0.2	GO:0071535	RING-like zinc finger domain binding(GO:0071535)
0.0	0.3	GO:0046972	histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.0	1.6	GO:0018024	histone-lysine N-methyltransferase activity(GO:0018024)
0.0	0.1	GO:0005173	stem cell factor receptor binding(GO:0005173)
0.0	2.5	GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.0	0.5	GO:0071837	HMG box domain binding(GO:0071837)
0.0	0.9	GO:0030159	receptor signaling complex scaffold activity(GO:0030159)
0.0	0.2	GO:0034481	chondroitin sulfotransferase activity(GO:0034481)
0.0	0.1	GO:0061629	RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.0	0.1	GO:0005115	receptor tyrosine kinase-like orphan receptor binding(GO:0005115) chemoattractant activity involved in axon guidance(GO:1902379)
0.0	0.4	GO:0005537	mannose binding(GO:0005537)
0.0	0.9	GO:0070577	lysine-acetylated histone binding(GO:0070577)
0.0	0.3	GO:0044213	intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.0	0.1	GO:0043184	vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.0	0.4	GO:0031702	type 1 angiotensin receptor binding(GO:0031702)
0.0	2.6	GO:0017022	myosin binding(GO:0017022)
0.0	0.1	GO:0004522	ribonuclease A activity(GO:0004522)
0.0	0.2	GO:0000340	RNA 7-methylguanosine cap binding(GO:0000340)
0.0	0.1	GO:0050816	phosphothreonine binding(GO:0050816)
0.0	0.9	GO:0071889	14-3-3 protein binding(GO:0071889)
0.0	0.3	GO:0015093	ferrous iron transmembrane transporter activity(GO:0015093)
0.0	0.5	GO:0042043	neurexin family protein binding(GO:0042043)
0.0	0.4	GO:0004535	poly(A)-specific ribonuclease activity(GO:0004535)
0.0	0.1	GO:0031962	mineralocorticoid receptor binding(GO:0031962)
0.0	0.6	GO:0000993	RNA polymerase II core binding(GO:0000993)
0.0	0.4	GO:0031005	filamin binding(GO:0031005)
0.0	1.1	GO:0042162	telomeric DNA binding(GO:0042162)
0.0	0.1	GO:0034057	RNA strand-exchange activity(GO:0034057)
0.0	0.3	GO:0052629	phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0	0.1	GO:0008889	glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.0	0.4	GO:0015467	G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0	0.3	GO:0019871	sodium channel inhibitor activity(GO:0019871)
0.0	0.8	GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0	0.3	GO:0000339	RNA cap binding(GO:0000339)
0.0	0.7	GO:0004003	ATP-dependent DNA helicase activity(GO:0004003)
0.0	0.1	GO:0008417	fucosyltransferase activity(GO:0008417)
0.0	0.5	GO:0017166	vinculin binding(GO:0017166)
0.0	0.3	GO:0050291	sphingosine N-acyltransferase activity(GO:0050291)
0.0	0.3	GO:0003678	DNA helicase activity(GO:0003678)
0.0	1.6	GO:0070035	ATP-dependent helicase activity(GO:0008026) purine NTP-dependent helicase activity(GO:0070035)
0.0	0.2	GO:0004652	polynucleotide adenylyltransferase activity(GO:0004652)
0.0	0.2	GO:0019534	toxin transporter activity(GO:0019534)
0.0	0.1	GO:0070139	ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.0	0.1	GO:0008454	alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0	0.2	GO:0043274	phospholipase binding(GO:0043274)
0.0	0.1	GO:0070569	uridylyltransferase activity(GO:0070569)
0.0	0.0	GO:0004584	dolichyl-phosphate-mannose-glycolipid alpha-mannosyltransferase activity(GO:0004584)
0.0	0.1	GO:0070051	fibrinogen binding(GO:0070051)
0.0	0.2	GO:0004689	phosphorylase kinase activity(GO:0004689)
0.0	0.2	GO:0005242	inward rectifier potassium channel activity(GO:0005242)
0.0	0.8	GO:0008536	Ran GTPase binding(GO:0008536)
0.0	0.0	GO:0097003	adipokinetic hormone receptor activity(GO:0097003)
0.0	0.2	GO:0048018	receptor agonist activity(GO:0048018)
0.0	0.1	GO:0004582	dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.0	2.2	GO:0004222	metalloendopeptidase activity(GO:0004222)
0.0	0.2	GO:0008494	translation activator activity(GO:0008494)
0.0	0.1	GO:0016929	SUMO-specific protease activity(GO:0016929)
0.0	1.1	GO:0043130	ubiquitin binding(GO:0043130)
0.0	0.2	GO:0003996	acyl-CoA ligase activity(GO:0003996)
0.0	0.1	GO:0048406	nerve growth factor binding(GO:0048406)
0.0	0.1	GO:0004616	phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.0	0.1	GO:0042608	T cell receptor binding(GO:0042608)
0.0	0.0	GO:0031433	telethonin binding(GO:0031433)
0.0	0.3	GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0	0.6	GO:0030374	ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0	0.1	GO:0005152	interleukin-1 receptor antagonist activity(GO:0005152)
0.0	0.1	GO:0030911	TPR domain binding(GO:0030911)
0.0	0.3	GO:0050321	tau-protein kinase activity(GO:0050321)
0.0	0.1	GO:0051011	microtubule minus-end binding(GO:0051011)
0.0	0.2	GO:0044548	S100 protein binding(GO:0044548)
0.0	0.1	GO:0042975	peroxisome proliferator activated receptor binding(GO:0042975)
0.0	0.1	GO:0051373	FATZ binding(GO:0051373)
0.0	0.4	GO:0005251	delayed rectifier potassium channel activity(GO:0005251)
0.0	0.9	GO:0004864	protein phosphatase inhibitor activity(GO:0004864)
0.0	0.5	GO:0051010	microtubule plus-end binding(GO:0051010)
0.0	0.1	GO:0098639	protein binding involved in cell-matrix adhesion(GO:0098634) collagen binding involved in cell-matrix adhesion(GO:0098639)
0.0	0.1	GO:0102338	fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0	0.1	GO:0016724	ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0	0.1	GO:0031624	ubiquitin conjugating enzyme binding(GO:0031624)
0.0	0.3	GO:0005522	profilin binding(GO:0005522)
0.0	0.1	GO:0072542	protein phosphatase activator activity(GO:0072542)
0.0	0.1	GO:0000213	tRNA-intron endonuclease activity(GO:0000213)
0.0	0.1	GO:0031995	insulin-like growth factor II binding(GO:0031995)
0.0	1.4	GO:0003697	single-stranded DNA binding(GO:0003697)
0.0	0.3	GO:0050700	CARD domain binding(GO:0050700)
0.0	0.4	GO:0030506	ankyrin binding(GO:0030506)
0.0	0.7	GO:0019888	protein phosphatase regulator activity(GO:0019888)
0.0	0.5	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0	1.3	GO:0004843	thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.0	0.1	GO:0017151	DEAD/H-box RNA helicase binding(GO:0017151)
0.0	0.1	GO:1990247	N6-methyladenosine-containing RNA binding(GO:1990247)
0.0	0.6	GO:0004693	cyclin-dependent protein serine/threonine kinase activity(GO:0004693)

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.4	SA CASPASE CASCADE	Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0	2.3	PID P38 MKK3 6PATHWAY	p38 MAPK signaling pathway
0.0	4.3	PID HDAC CLASSII PATHWAY	Signaling events mediated by HDAC Class II
0.0	0.7	ST STAT3 PATHWAY	STAT3 Pathway
0.0	3.7	PID UPA UPAR PATHWAY	Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0	1.4	PID INTEGRIN A9B1 PATHWAY	Alpha9 beta1 integrin signaling events
0.0	1.8	PID IL2 STAT5 PATHWAY	IL2 signaling events mediated by STAT5
0.0	1.9	PID INTEGRIN3 PATHWAY	Beta3 integrin cell surface interactions
0.0	0.7	PID SMAD2 3PATHWAY	Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0	3.1	PID AJDISS 2PATHWAY	Posttranslational regulation of adherens junction stability and dissassembly
0.0	2.0	PID NEPHRIN NEPH1 PATHWAY	Nephrin/Neph1 signaling in the kidney podocyte
0.0	0.7	PID SYNDECAN 3 PATHWAY	Syndecan-3-mediated signaling events
0.0	0.8	PID ALK1 PATHWAY	ALK1 signaling events
0.0	1.5	PID FAK PATHWAY	Signaling events mediated by focal adhesion kinase
0.0	0.9	PID WNT CANONICAL PATHWAY	Canonical Wnt signaling pathway
0.0	0.6	PID ECADHERIN KERATINOCYTE PATHWAY	E-cadherin signaling in keratinocytes
0.0	0.7	PID CERAMIDE PATHWAY	Ceramide signaling pathway
0.0	2.2	PID PLK1 PATHWAY	PLK1 signaling events
0.0	1.0	PID TNF PATHWAY	TNF receptor signaling pathway
0.0	2.0	PID TGFBR PATHWAY	TGF-beta receptor signaling
0.0	0.5	PID ECADHERIN NASCENT AJ PATHWAY	E-cadherin signaling in the nascent adherens junction
0.0	1.0	PID IGF1 PATHWAY	IGF1 pathway
0.0	2.4	PID CDC42 PATHWAY	CDC42 signaling events
0.0	0.8	PID HIF1A PATHWAY	Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0	1.8	PID BCR 5PATHWAY	BCR signaling pathway
0.0	0.8	PID TOLL ENDOGENOUS PATHWAY	Endogenous TLR signaling
0.0	1.0	PID KIT PATHWAY	Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0	0.2	PID SYNDECAN 2 PATHWAY	Syndecan-2-mediated signaling events
0.0	1.6	PID DELTA NP63 PATHWAY	Validated transcriptional targets of deltaNp63 isoforms
0.0	0.2	PID PRL SIGNALING EVENTS PATHWAY	Signaling events mediated by PRL
0.0	0.0	PID S1P S1P1 PATHWAY	S1P1 pathway
0.0	2.0	PID CASPASE PATHWAY	Caspase cascade in apoptosis
0.0	0.3	PID LYMPH ANGIOGENESIS PATHWAY	VEGFR3 signaling in lymphatic endothelium
0.0	0.5	PID CIRCADIAN PATHWAY	Circadian rhythm pathway
0.0	0.4	PID EPHRINB REV PATHWAY	Ephrin B reverse signaling
0.0	1.3	PID P53 REGULATION PATHWAY	p53 pathway
0.0	0.2	PID IFNG PATHWAY	IFN-gamma pathway
0.0	1.1	PID NOTCH PATHWAY	Notch signaling pathway
0.0	0.2	PID NECTIN PATHWAY	Nectin adhesion pathway
0.0	0.4	PID HDAC CLASSIII PATHWAY	Signaling events mediated by HDAC Class III
0.0	0.6	PID ECADHERIN STABILIZATION PATHWAY	Stabilization and expansion of the E-cadherin adherens junction
0.0	0.1	PID VEGF VEGFR PATHWAY	VEGF and VEGFR signaling network
0.0	0.2	PID ARF6 DOWNSTREAM PATHWAY	Arf6 downstream pathway
0.0	0.3	PID ERBB2 ERBB3 PATHWAY	ErbB2/ErbB3 signaling events
0.0	1.3	PID BETA CATENIN NUC PATHWAY	Regulation of nuclear beta catenin signaling and target gene transcription
0.0	0.2	PID LYSOPHOSPHOLIPID PATHWAY	LPA receptor mediated events
0.0	0.6	PID IL4 2PATHWAY	IL4-mediated signaling events
0.0	0.2	PID ERB GENOMIC PATHWAY	Validated nuclear estrogen receptor beta network
0.0	0.7	NABA BASEMENT MEMBRANES	Genes encoding structural components of basement membranes

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	2.6	REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION	Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.2	0.4	REACTOME SOS MEDIATED SIGNALLING	Genes involved in SOS-mediated signalling
0.2	2.5	REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR	Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.1	2.2	REACTOME MTORC1 MEDIATED SIGNALLING	Genes involved in mTORC1-mediated signalling
0.1	1.2	REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE	Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0	2.0	REACTOME HS GAG BIOSYNTHESIS	Genes involved in HS-GAG biosynthesis
0.0	2.3	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.0	1.2	REACTOME ALPHA LINOLENIC ACID ALA METABOLISM	Genes involved in alpha-linolenic acid (ALA) metabolism
0.0	0.8	REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION	Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0	0.7	REACTOME THE ACTIVATION OF ARYLSULFATASES	Genes involved in The activation of arylsulfatases
0.0	1.4	REACTOME DEADENYLATION OF MRNA	Genes involved in Deadenylation of mRNA
0.0	0.8	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.0	1.0	REACTOME CTNNB1 PHOSPHORYLATION CASCADE	Genes involved in Beta-catenin phosphorylation cascade
0.0	0.6	REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS	Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0	1.2	REACTOME FORMATION OF INCISION COMPLEX IN GG NER	Genes involved in Formation of incision complex in GG-NER
0.0	2.2	REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION	Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0	0.2	REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0	1.9	REACTOME G1 PHASE	Genes involved in G1 Phase
0.0	4.1	REACTOME MITOTIC PROMETAPHASE	Genes involved in Mitotic Prometaphase
0.0	0.5	REACTOME DESTABILIZATION OF MRNA BY KSRP	Genes involved in Destabilization of mRNA by KSRP
0.0	0.6	REACTOME COMMON PATHWAY	Genes involved in Common Pathway
0.0	2.5	REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION	Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0	0.2	REACTOME ARMS MEDIATED ACTIVATION	Genes involved in ARMS-mediated activation
0.0	0.6	REACTOME ACTIVATION OF NF KAPPAB IN B CELLS	Genes involved in Activation of NF-kappaB in B Cells
0.0	0.5	REACTOME IL 6 SIGNALING	Genes involved in Interleukin-6 signaling
0.0	0.6	REACTOME G0 AND EARLY G1	Genes involved in G0 and Early G1
0.0	0.3	REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the late endosome membrane
0.0	0.1	REACTOME RETROGRADE NEUROTROPHIN SIGNALLING	Genes involved in Retrograde neurotrophin signalling
0.0	0.5	REACTOME DESTABILIZATION OF MRNA BY BRF1	Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.0	0.9	REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN	Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.0	0.5	REACTOME SHC1 EVENTS IN EGFR SIGNALING	Genes involved in SHC1 events in EGFR signaling
0.0	0.5	REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS	Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements
0.0	0.4	REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE	Genes involved in Synthesis of PIPs at the Golgi membrane
0.0	0.8	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.0	0.3	REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION	Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0	0.6	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
0.0	0.5	REACTOME HYALURONAN METABOLISM	Genes involved in Hyaluronan metabolism
0.0	1.4	REACTOME MITOCHONDRIAL PROTEIN IMPORT	Genes involved in Mitochondrial Protein Import
0.0	0.6	REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX	Genes involved in Degradation of the extracellular matrix
0.0	1.0	REACTOME RECYCLING PATHWAY OF L1	Genes involved in Recycling pathway of L1
0.0	0.6	REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS	Genes involved in Glycogen breakdown (glycogenolysis)
0.0	0.4	REACTOME HDL MEDIATED LIPID TRANSPORT	Genes involved in HDL-mediated lipid transport
0.0	0.7	REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	Genes involved in DCC mediated attractive signaling
0.0	0.6	REACTOME LYSOSOME VESICLE BIOGENESIS	Genes involved in Lysosome Vesicle Biogenesis
0.0	0.7	REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE	Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0	1.7	REACTOME NRAGE SIGNALS DEATH THROUGH JNK	Genes involved in NRAGE signals death through JNK
0.0	0.6	REACTOME CIRCADIAN CLOCK	Genes involved in Circadian Clock
0.0	0.3	REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT	Genes involved in Chylomicron-mediated lipid transport
0.0	0.6	REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING	Genes involved in Downregulation of TGF-beta receptor signaling
0.0	0.8	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
0.0	0.6	REACTOME THROMBOXANE SIGNALLING THROUGH TP RECEPTOR	Genes involved in Thromboxane signalling through TP receptor
0.0	0.1	REACTOME ACTIVATION OF BH3 ONLY PROTEINS	Genes involved in Activation of BH3-only proteins
0.0	0.4	REACTOME CRMPS IN SEMA3A SIGNALING	Genes involved in CRMPs in Sema3A signaling
0.0	0.3	REACTOME METABOLISM OF NON CODING RNA	Genes involved in Metabolism of non-coding RNA
0.0	0.4	REACTOME GLUCURONIDATION	Genes involved in Glucuronidation
0.0	0.5	REACTOME TRANSCRIPTIONAL ACTIVITY OF SMAD2 SMAD3 SMAD4 HETEROTRIMER	Genes involved in Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer
0.0	0.4	REACTOME NEPHRIN INTERACTIONS	Genes involved in Nephrin interactions
0.0	0.4	REACTOME SIGNALING BY BMP	Genes involved in Signaling by BMP
0.0	0.3	REACTOME IL RECEPTOR SHC SIGNALING	Genes involved in Interleukin receptor SHC signaling
0.0	0.3	REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS	Genes involved in Bile salt and organic anion SLC transporters
0.0	1.2	REACTOME O LINKED GLYCOSYLATION OF MUCINS	Genes involved in O-linked glycosylation of mucins
0.0	0.2	REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS	Genes involved in Tandem pore domain potassium channels
0.0	0.1	REACTOME GLYCOPROTEIN HORMONES	Genes involved in Glycoprotein hormones
0.0	0.6	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
0.0	0.6	REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS	Genes involved in Golgi Associated Vesicle Biogenesis
0.0	0.6	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.0	3.3	REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION	Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0	0.2	REACTOME PRE NOTCH PROCESSING IN GOLGI	Genes involved in Pre-NOTCH Processing in Golgi
0.0	0.4	REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING	Genes involved in Negative regulators of RIG-I/MDA5 signaling

Results for GTF2I

Z-value: 0.92

Motif logo

Transcription factors associated with GTF2I

Activity-expression correlation:

Activity profile of GTF2I motif

Sorted Z-values of GTF2I motif

Top targets:

Network of associatons between targets according to the STRING database.

First level regulatory network of GTF2I

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Gene overrepresentation in cellular_component category:

Gene overrepresentation in molecular_function category:

Gene overrepresentation in C2:CP category:

Gene overrepresentation in C2:CP:REACTOME category: