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SARS-CoV-2 Analysis Results (GEO series: GSE147507)
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Results for GUGCAAA
Z-value: 0.97
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miRNA associated with seed GUGCAAA
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr2_-_1748214 Show fit | 3.70 |
ENST00000433670.1
ENST00000425171.1 ENST00000252804.4 |
peroxidasin homolog (Drosophila) |
|
| chr15_+_39873268 Show fit | 3.46 |
ENST00000397591.2
ENST00000260356.5 |
thrombospondin 1 |
|
| chr15_+_98503922 Show fit | 3.35 |
ENST00000268042.6
|
arrestin domain containing 4 |
|
| chr12_+_4382917 Show fit | 3.35 |
ENST00000261254.3
|
cyclin D2 |
|
| chr13_-_107187462 Show fit | 3.12 |
ENST00000245323.4
|
ephrin-B2 |
|
| chr5_-_136834982 Show fit | 2.83 |
ENST00000510689.1
ENST00000394945.1 |
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 |
|
| chr3_-_52090461 Show fit | 2.50 |
ENST00000296483.6
ENST00000495880.1 |
dual specificity phosphatase 7 |
|
| chr22_+_40390930 Show fit | 2.08 |
ENST00000333407.6
|
family with sequence similarity 83, member F |
|
| chr18_-_61089665 Show fit | 2.05 |
ENST00000238497.5
|
vacuolar protein sorting 4 homolog B (S. cerevisiae) |
|
| chr8_-_124553437 Show fit | 1.94 |
ENST00000517956.1
ENST00000443022.2 |
F-box protein 32 |
Network of associatons between targets according to the STRING database.
First level regulatory network of GUGCAAA
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 3.7 | GO:0042744 | hydrogen peroxide catabolic process(GO:0042744) |
| 0.0 | 3.7 | GO:0051443 | positive regulation of ubiquitin-protein transferase activity(GO:0051443) |
| 1.2 | 3.5 | GO:0002605 | negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581) negative regulation of dendritic cell antigen processing and presentation(GO:0002605) negative regulation of endothelial cell chemotaxis(GO:2001027) |
| 0.1 | 3.3 | GO:0071481 | cellular response to X-ray(GO:0071481) |
| 0.2 | 3.1 | GO:0010839 | negative regulation of keratinocyte proliferation(GO:0010839) |
| 0.1 | 3.0 | GO:0006607 | NLS-bearing protein import into nucleus(GO:0006607) |
| 0.5 | 2.8 | GO:0090283 | regulation of protein glycosylation in Golgi(GO:0090283) |
| 0.3 | 2.8 | GO:0030579 | ubiquitin-dependent SMAD protein catabolic process(GO:0030579) |
| 0.1 | 2.5 | GO:0000188 | inactivation of MAPK activity(GO:0000188) |
| 0.0 | 2.3 | GO:0043551 | regulation of phosphatidylinositol 3-kinase activity(GO:0043551) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 4.1 | GO:0055037 | recycling endosome(GO:0055037) |
| 0.0 | 3.9 | GO:0005811 | lipid particle(GO:0005811) |
| 0.2 | 3.5 | GO:0005577 | fibrinogen complex(GO:0005577) |
| 0.4 | 3.3 | GO:0097129 | cyclin D2-CDK4 complex(GO:0097129) |
| 0.0 | 3.2 | GO:0019005 | SCF ubiquitin ligase complex(GO:0019005) |
| 0.0 | 3.2 | GO:0016605 | PML body(GO:0016605) |
| 0.0 | 2.9 | GO:0008023 | transcription elongation factor complex(GO:0008023) |
| 0.0 | 2.9 | GO:0016528 | sarcoplasm(GO:0016528) |
| 0.0 | 2.7 | GO:0031463 | Cul3-RING ubiquitin ligase complex(GO:0031463) |
| 0.1 | 2.5 | GO:0090543 | Flemming body(GO:0090543) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.7 | 3.7 | GO:0005152 | interleukin-1 receptor antagonist activity(GO:0005152) |
| 0.9 | 3.5 | GO:0070052 | collagen V binding(GO:0070052) |
| 0.1 | 2.8 | GO:0008191 | metalloendopeptidase inhibitor activity(GO:0008191) |
| 0.1 | 2.5 | GO:0017017 | MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017) |
| 0.1 | 2.5 | GO:0008139 | nuclear localization sequence binding(GO:0008139) |
| 0.1 | 2.0 | GO:0004707 | MAP kinase activity(GO:0004707) |
| 0.0 | 2.0 | GO:0030742 | GTP-dependent protein binding(GO:0030742) |
| 0.0 | 2.0 | GO:0046875 | ephrin receptor binding(GO:0046875) |
| 0.0 | 2.0 | GO:0017112 | Rab guanyl-nucleotide exchange factor activity(GO:0017112) |
| 0.5 | 1.9 | GO:0004142 | diacylglycerol cholinephosphotransferase activity(GO:0004142) phosphatidate cytidylyltransferase activity(GO:0004605) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 4.8 | PID EPHB FWD PATHWAY | EPHB forward signaling |
| 0.0 | 3.5 | PID LKB1 PATHWAY | LKB1 signaling events |
| 0.1 | 3.4 | PID ALK1 PATHWAY | ALK1 signaling events |
| 0.1 | 3.3 | PID IL2 STAT5 PATHWAY | IL2 signaling events mediated by STAT5 |
| 0.1 | 3.2 | PID SYNDECAN 4 PATHWAY | Syndecan-4-mediated signaling events |
| 0.0 | 3.2 | PID ERBB1 INTERNALIZATION PATHWAY | Internalization of ErbB1 |
| 0.0 | 2.8 | NABA PROTEOGLYCANS | Genes encoding proteoglycans |
| 0.0 | 2.6 | PID TGFBR PATHWAY | TGF-beta receptor signaling |
| 0.0 | 1.9 | PID HEDGEHOG GLI PATHWAY | Hedgehog signaling events mediated by Gli proteins |
| 0.0 | 1.7 | PID ECADHERIN NASCENT AJ PATHWAY | E-cadherin signaling in the nascent adherens junction |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 4.1 | REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 | Genes involved in Response to elevated platelet cytosolic Ca2+ |
| 0.1 | 3.7 | REACTOME G1 PHASE | Genes involved in G1 Phase |
| 0.1 | 3.1 | REACTOME ERKS ARE INACTIVATED | Genes involved in ERKs are inactivated |
| 0.1 | 2.6 | REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT | Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT) |
| 0.0 | 2.6 | REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS | Genes involved in Golgi Associated Vesicle Biogenesis |
| 0.1 | 2.5 | REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION | Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) |
| 0.1 | 2.3 | REACTOME REGULATION OF SIGNALING BY CBL | Genes involved in Regulation of signaling by CBL |
| 0.0 | 2.0 | REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS | Genes involved in Apoptotic cleavage of cellular proteins |
| 0.0 | 1.9 | REACTOME SIGNALING BY BMP | Genes involved in Signaling by BMP |
| 0.1 | 1.7 | REACTOME PROLONGED ERK ACTIVATION EVENTS | Genes involved in Prolonged ERK activation events |