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SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for GZF1

Z-value: 0.32

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Transcription factors associated with GZF1

Gene Symbol Gene ID Gene Info
GZF1
ENSG00000125812.11 GDNF inducible zinc finger protein 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
GZF1hg19_v2_chr20_+_23342783_233429570.106.6e-01Click!

Activity profile of GZF1 motif

Sorted Z-values of GZF1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr19_+_36157715 0.97 ENST00000379013.2
ENST00000222275.2
UPK1A
uroplakin 1A
chr5_+_92919043 0.93 ENST00000327111.3
NR2F1
nuclear receptor subfamily 2, group F, member 1
chr11_-_17498348 0.83 ENST00000389817.3
ENST00000302539.4
ABCC8
ATP-binding cassette, sub-family C (CFTR/MRP), member 8
chr7_-_27183263 0.77 ENST00000222726.3
HOXA5
homeobox A5
chr3_-_114035026 0.72 ENST00000570269.1
RP11-553L6.5
RP11-553L6.5
chr16_+_67876180 0.71 ENST00000303596.1
THAP11
THAP domain containing 11
chr11_+_101918153 0.60 ENST00000434758.2
ENST00000526781.1
ENST00000534360.1
C11orf70
chromosome 11 open reading frame 70
chr10_+_89264625 0.53 ENST00000371996.4
ENST00000371994.4
MINPP1
multiple inositol-polyphosphate phosphatase 1
chr19_-_59084922 0.46 ENST00000215057.2
ENST00000599369.1
MZF1
myeloid zinc finger 1
chr16_+_87636474 0.43 ENST00000284262.2
JPH3
junctophilin 3
chr14_-_92413727 0.43 ENST00000267620.10
FBLN5
fibulin 5
chr8_+_23430157 0.43 ENST00000399967.3
FP15737
FP15737
chr12_+_54384370 0.38 ENST00000504315.1
HOXC6
homeobox C6
chr14_-_59950724 0.36 ENST00000481608.1
L3HYPDH
L-3-hydroxyproline dehydratase (trans-)
chr1_+_41174988 0.32 ENST00000372652.1
NFYC
nuclear transcription factor Y, gamma
chr19_-_59084647 0.32 ENST00000594234.1
ENST00000596039.1
MZF1
myeloid zinc finger 1
chr5_+_170814803 0.32 ENST00000521672.1
ENST00000351986.6
ENST00000393820.2
ENST00000523622.1
NPM1
nucleophosmin (nucleolar phosphoprotein B23, numatrin)
chr14_-_92413353 0.30 ENST00000556154.1
FBLN5
fibulin 5
chr19_-_36545128 0.29 ENST00000538849.1
THAP8
THAP domain containing 8
chr12_-_76478417 0.27 ENST00000552342.1
NAP1L1
nucleosome assembly protein 1-like 1
chr19_+_38880252 0.27 ENST00000586301.1
SPRED3
sprouty-related, EVH1 domain containing 3
chr12_+_102513950 0.26 ENST00000378128.3
ENST00000327680.2
ENST00000541394.1
ENST00000543784.1
PARPBP
PARP1 binding protein
chrX_+_153238220 0.25 ENST00000425274.1
TMEM187
transmembrane protein 187
chr20_-_31331212 0.24 ENST00000474815.2
ENST00000446419.2
COMMD7
COMM domain containing 7
chr8_+_144373550 0.23 ENST00000330143.3
ENST00000521537.1
ENST00000518432.1
ENST00000520333.1
ZNF696
zinc finger protein 696
chr1_-_201438282 0.23 ENST00000367311.3
ENST00000367309.1
PHLDA3
pleckstrin homology-like domain, family A, member 3
chr12_-_107168696 0.23 ENST00000551505.1
RP11-144F15.1
Uncharacterized protein
chr12_-_102513843 0.23 ENST00000551744.2
ENST00000552283.1
NUP37
nucleoporin 37kDa
chr20_+_42086525 0.22 ENST00000244020.3
SRSF6
serine/arginine-rich splicing factor 6
chr6_+_30525051 0.22 ENST00000376557.3
PRR3
proline rich 3
chr1_-_32801825 0.21 ENST00000329421.7
MARCKSL1
MARCKS-like 1
chr6_+_30524663 0.21 ENST00000376560.3
PRR3
proline rich 3
chrX_+_54835493 0.20 ENST00000396224.1
MAGED2
melanoma antigen family D, 2
chr12_-_76478446 0.19 ENST00000393263.3
ENST00000548044.1
ENST00000547704.1
ENST00000431879.3
ENST00000549596.1
ENST00000550934.1
ENST00000551600.1
ENST00000547479.1
ENST00000547773.1
ENST00000544816.1
ENST00000542344.1
ENST00000548273.1
NAP1L1
nucleosome assembly protein 1-like 1
chr3_+_51705222 0.17 ENST00000457573.1
ENST00000341333.5
ENST00000412249.1
ENST00000425781.1
ENST00000415259.1
ENST00000395057.1
ENST00000416589.1
TEX264
testis expressed 264
chr12_-_76478386 0.16 ENST00000535020.2
NAP1L1
nucleosome assembly protein 1-like 1
chr9_+_96338860 0.16 ENST00000375376.4
PHF2
PHD finger protein 2
chr2_-_27603582 0.16 ENST00000323703.6
ENST00000436006.1
ZNF513
zinc finger protein 513
chr10_-_16563870 0.15 ENST00000298943.3
C1QL3
complement component 1, q subcomponent-like 3
chr22_+_50639408 0.15 ENST00000380903.2
SELO
Selenoprotein O
chr14_-_52535712 0.14 ENST00000216286.5
ENST00000541773.1
NID2
nidogen 2 (osteonidogen)
chr19_+_38880695 0.12 ENST00000587947.1
ENST00000338502.4
SPRED3
sprouty-related, EVH1 domain containing 3
chr19_-_3786253 0.12 ENST00000585778.1
MATK
megakaryocyte-associated tyrosine kinase
chr14_-_21979428 0.12 ENST00000538267.1
ENST00000298717.4
METTL3
methyltransferase like 3
chr14_-_53619816 0.10 ENST00000323669.5
ENST00000395606.1
ENST00000357758.3
DDHD1
DDHD domain containing 1
chr16_+_86612112 0.10 ENST00000320241.3
FOXL1
forkhead box L1
chr9_+_131133598 0.10 ENST00000372853.4
ENST00000452446.1
ENST00000372850.1
ENST00000372847.1
URM1
ubiquitin related modifier 1
chrX_+_102883620 0.09 ENST00000372626.3
TCEAL1
transcription elongation factor A (SII)-like 1
chr17_-_29648761 0.09 ENST00000247270.3
ENST00000462804.2
EVI2A
ecotropic viral integration site 2A
chr5_-_176827631 0.09 ENST00000358571.2
PFN3
profilin 3
chr19_-_52150053 0.07 ENST00000599649.1
ENST00000429354.3
ENST00000360844.6
ENST00000222107.4
SIGLEC5
SIGLEC14
SIGLEC5
SIGLEC5
sialic acid binding Ig-like lectin 14
sialic acid binding Ig-like lectin 5
chr19_-_3786354 0.07 ENST00000395040.2
ENST00000310132.6
MATK
megakaryocyte-associated tyrosine kinase
chr3_+_51705844 0.07 ENST00000457927.1
ENST00000444233.1
TEX264
testis expressed 264
chr10_+_97759848 0.06 ENST00000424464.1
ENST00000410012.2
ENST00000344386.3
CC2D2B
coiled-coil and C2 domain containing 2B
chr15_+_78370140 0.06 ENST00000409568.2
SH2D7
SH2 domain containing 7
chr16_-_70285797 0.06 ENST00000435634.1
EXOSC6
exosome component 6
chr9_+_96338647 0.05 ENST00000359246.4
PHF2
PHD finger protein 2
chr12_+_107168418 0.04 ENST00000392839.2
ENST00000548914.1
ENST00000355478.2
ENST00000552619.1
ENST00000549643.1
RIC8B
RIC8 guanine nucleotide exchange factor B
chr9_-_124976185 0.04 ENST00000464484.2
LHX6
LIM homeobox 6
chr2_-_150444300 0.04 ENST00000303319.5
MMADHC
methylmalonic aciduria (cobalamin deficiency) cblD type, with homocystinuria
chr16_-_30582888 0.04 ENST00000563707.1
ENST00000567855.1
ZNF688
zinc finger protein 688
chr2_-_150444116 0.03 ENST00000428879.1
ENST00000422782.2
MMADHC
methylmalonic aciduria (cobalamin deficiency) cblD type, with homocystinuria
chr3_-_170588163 0.03 ENST00000295830.8
RPL22L1
ribosomal protein L22-like 1
chr16_-_46797149 0.02 ENST00000536476.1
MYLK3
myosin light chain kinase 3
chr11_+_64937625 0.02 ENST00000377185.2
SPDYC
speedy/RINGO cell cycle regulator family member C
chr2_-_74776586 0.02 ENST00000420535.1
LOXL3
lysyl oxidase-like 3
chr4_+_2451700 0.02 ENST00000506607.1
RP11-503N18.3
Uncharacterized protein
chr10_+_60028818 0.01 ENST00000333926.5
CISD1
CDGSH iron sulfur domain 1
chr7_+_102004322 0.01 ENST00000496391.1
PRKRIP1
PRKR interacting protein 1 (IL11 inducible)
chr2_-_88427568 0.01 ENST00000393750.3
ENST00000295834.3
FABP1
fatty acid binding protein 1, liver
chr4_-_89619386 0.01 ENST00000323061.5
NAP1L5
nucleosome assembly protein 1-like 5
chr18_-_53303123 0.00 ENST00000569357.1
ENST00000565124.1
ENST00000398339.1
TCF4
transcription factor 4
chr19_-_10426663 0.00 ENST00000541276.1
ENST00000393708.3
ENST00000494368.1
FDX1L
ferredoxin 1-like
chr1_-_2461684 0.00 ENST00000378453.3
HES5
hes family bHLH transcription factor 5

Network of associatons between targets according to the STRING database.

First level regulatory network of GZF1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.8 GO:1901079 positive regulation of relaxation of muscle(GO:1901079)
0.2 0.8 GO:0060535 trachea cartilage morphogenesis(GO:0060535)
0.1 0.7 GO:0048251 elastic fiber assembly(GO:0048251)
0.0 0.2 GO:0061188 negative regulation of chromatin silencing at rDNA(GO:0061188)
0.0 0.3 GO:0060699 regulation of endoribonuclease activity(GO:0060699)
0.0 0.1 GO:0006382 adenosine to inosine editing(GO:0006382)
0.0 0.2 GO:0060501 negative regulation of keratinocyte differentiation(GO:0045617) positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501)
0.0 0.3 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.0 0.1 GO:0034227 tRNA thio-modification(GO:0034227)
0.0 0.2 GO:0070294 renal sodium ion absorption(GO:0070294)
0.0 0.1 GO:0061146 Peyer's patch morphogenesis(GO:0061146)
0.0 0.1 GO:0071051 polyadenylation-dependent snoRNA 3'-end processing(GO:0071051)
0.0 0.4 GO:0035640 exploration behavior(GO:0035640)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.1 0.7 GO:0071953 elastic fiber(GO:0071953)
0.0 0.4 GO:0030314 junctional membrane complex(GO:0030314)
0.0 0.3 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 0.1 GO:0036396 MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
0.0 0.3 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 0.2 GO:0031080 nuclear pore outer ring(GO:0031080)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.8 GO:0008281 sulfonylurea receptor activity(GO:0008281)
0.2 0.5 GO:0008969 phosphohistidine phosphatase activity(GO:0008969)
0.1 0.4 GO:0047661 racemase and epimerase activity, acting on amino acids and derivatives(GO:0016855) racemase activity, acting on amino acids and derivatives(GO:0036361) amino-acid racemase activity(GO:0047661)
0.1 0.9 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.0 0.1 GO:0016422 mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity(GO:0016422)
0.0 0.3 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.0 0.4 GO:0015278 calcium-release channel activity(GO:0015278) ligand-gated calcium channel activity(GO:0099604)
0.0 0.2 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.8 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport