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SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for HAND1

Z-value: 0.61

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Transcription factors associated with HAND1

Gene Symbol Gene ID Gene Info
HAND1
ENSG00000113196.2 heart and neural crest derivatives expressed 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HAND1hg19_v2_chr5_-_153857819_1538578240.435.8e-02Click!

Activity profile of HAND1 motif

Sorted Z-values of HAND1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr19_+_36359341 3.84 ENST00000221891.4
APLP1
amyloid beta (A4) precursor-like protein 1
chr12_+_52450298 2.85 ENST00000550582.2
NR4A1
nuclear receptor subfamily 4, group A, member 1
chr2_+_228678550 1.93 ENST00000409189.3
ENST00000358813.4
CCL20
chemokine (C-C motif) ligand 20
chr19_-_36304201 1.79 ENST00000301175.3
PRODH2
proline dehydrogenase (oxidase) 2
chr19_+_507299 1.76 ENST00000359315.5
TPGS1
tubulin polyglutamylase complex subunit 1
chr17_-_64216748 1.71 ENST00000585162.1
APOH
apolipoprotein H (beta-2-glycoprotein I)
chr14_-_65409502 1.65 ENST00000389614.5
GPX2
glutathione peroxidase 2 (gastrointestinal)
chr22_+_24999114 1.45 ENST00000412658.1
ENST00000445029.1
ENST00000419133.1
ENST00000400382.1
ENST00000438643.2
ENST00000452551.1
ENST00000400383.1
ENST00000412898.1
ENST00000400380.1
ENST00000455483.1
ENST00000430289.1
GGT1
gamma-glutamyltransferase 1
chr1_+_164528866 1.42 ENST00000420696.2
PBX1
pre-B-cell leukemia homeobox 1
chr20_-_1165117 1.38 ENST00000381894.3
TMEM74B
transmembrane protein 74B
chr22_+_25003626 1.32 ENST00000451366.1
ENST00000406383.2
ENST00000428855.1
GGT1
gamma-glutamyltransferase 1
chr20_-_1165319 1.21 ENST00000429036.1
TMEM74B
transmembrane protein 74B
chr14_-_65409438 1.17 ENST00000557049.1
GPX2
glutathione peroxidase 2 (gastrointestinal)
chr14_+_96722152 1.17 ENST00000216629.6
BDKRB1
bradykinin receptor B1
chrX_+_70364667 1.11 ENST00000536169.1
ENST00000395855.2
ENST00000374051.3
ENST00000358741.3
NLGN3
neuroligin 3
chr3_-_9811595 1.10 ENST00000256460.3
CAMK1
calcium/calmodulin-dependent protein kinase I
chr4_+_41614909 1.07 ENST00000509454.1
ENST00000396595.3
ENST00000381753.4
LIMCH1
LIM and calponin homology domains 1
chr14_+_96722539 0.98 ENST00000553356.1
BDKRB1
bradykinin receptor B1
chr3_-_114035026 0.98 ENST00000570269.1
RP11-553L6.5
RP11-553L6.5
chr22_+_25003606 0.84 ENST00000432867.1
GGT1
gamma-glutamyltransferase 1
chr2_-_42588289 0.83 ENST00000468711.1
ENST00000463055.1
COX7A2L
cytochrome c oxidase subunit VIIa polypeptide 2 like
chr22_+_25003568 0.80 ENST00000447416.1
GGT1
gamma-glutamyltransferase 1
chr19_-_10213335 0.80 ENST00000592641.1
ENST00000253109.4
ANGPTL6
angiopoietin-like 6
chr1_-_54405773 0.75 ENST00000371376.1
HSPB11
heat shock protein family B (small), member 11
chr20_+_3713314 0.74 ENST00000254963.2
ENST00000542646.1
ENST00000399701.1
HSPA12B
heat shock 70kD protein 12B
chr16_-_70729496 0.65 ENST00000567648.1
VAC14
Vac14 homolog (S. cerevisiae)
chr12_+_49717019 0.65 ENST00000549275.1
ENST00000551245.1
ENST00000380327.5
ENST00000548311.1
ENST00000550346.1
ENST00000550709.1
ENST00000549534.1
ENST00000257909.3
TROAP
trophinin associated protein
chr1_-_32210275 0.64 ENST00000440175.2
BAI2
brain-specific angiogenesis inhibitor 2
chr17_+_45908974 0.64 ENST00000269025.4
LRRC46
leucine rich repeat containing 46
chr17_-_43025005 0.64 ENST00000587309.1
ENST00000593135.1
ENST00000339151.4
KIF18B
kinesin family member 18B
chr20_+_3767547 0.63 ENST00000344256.6
ENST00000379598.5
CDC25B
cell division cycle 25B
chr15_+_74509530 0.61 ENST00000321288.5
CCDC33
coiled-coil domain containing 33
chrX_-_34675391 0.59 ENST00000275954.3
TMEM47
transmembrane protein 47
chr7_+_76139833 0.55 ENST00000257632.5
UPK3B
uroplakin 3B
chr2_-_228582709 0.52 ENST00000541617.1
ENST00000409456.2
ENST00000409287.1
ENST00000258403.3
SLC19A3
solute carrier family 19 (thiamine transporter), member 3
chr17_+_6347761 0.51 ENST00000250056.8
ENST00000571373.1
ENST00000570337.2
ENST00000572595.2
ENST00000576056.1
FAM64A
family with sequence similarity 64, member A
chr10_-_118032697 0.51 ENST00000439649.3
GFRA1
GDNF family receptor alpha 1
chr14_-_93673353 0.51 ENST00000556566.1
ENST00000306954.4
C14orf142
chromosome 14 open reading frame 142
chr19_+_18492973 0.50 ENST00000595973.2
GDF15
growth differentiation factor 15
chr12_+_53848549 0.50 ENST00000439930.3
ENST00000548933.1
ENST00000562264.1
PCBP2
poly(rC) binding protein 2
chr12_+_53848505 0.49 ENST00000552819.1
ENST00000455667.3
PCBP2
poly(rC) binding protein 2
chr6_+_134210243 0.49 ENST00000367882.4
TCF21
transcription factor 21
chr4_+_41614720 0.48 ENST00000509277.1
LIMCH1
LIM and calponin homology domains 1
chr22_-_39928823 0.48 ENST00000334678.3
RPS19BP1
ribosomal protein S19 binding protein 1
chr16_-_4303767 0.47 ENST00000573268.1
ENST00000573042.1
RP11-95P2.1
RP11-95P2.1
chr2_+_98262497 0.47 ENST00000258424.2
COX5B
cytochrome c oxidase subunit Vb
chr1_+_28261621 0.45 ENST00000549094.1
SMPDL3B
sphingomyelin phosphodiesterase, acid-like 3B
chr21_-_16125773 0.43 ENST00000454128.2
AF127936.3
AF127936.3
chr1_+_28261492 0.42 ENST00000373894.3
SMPDL3B
sphingomyelin phosphodiesterase, acid-like 3B
chr3_-_20227619 0.42 ENST00000425061.1
ENST00000443724.1
ENST00000421451.1
ENST00000452020.1
ENST00000417364.1
ENST00000306698.2
ENST00000419233.2
ENST00000263753.4
ENST00000383774.1
ENST00000437051.1
ENST00000412868.1
ENST00000429446.3
ENST00000442720.1
SGOL1
shugoshin-like 1 (S. pombe)
chr17_-_61781750 0.42 ENST00000582026.1
STRADA
STE20-related kinase adaptor alpha
chr11_+_369804 0.41 ENST00000329962.6
B4GALNT4
beta-1,4-N-acetyl-galactosaminyl transferase 4
chr2_-_42588338 0.40 ENST00000234301.2
COX7A2L
cytochrome c oxidase subunit VIIa polypeptide 2 like
chrX_+_149531524 0.40 ENST00000370401.2
MAMLD1
mastermind-like domain containing 1
chr10_-_118032979 0.39 ENST00000355422.6
GFRA1
GDNF family receptor alpha 1
chr12_-_7261772 0.39 ENST00000545280.1
ENST00000543933.1
ENST00000545337.1
ENST00000544702.1
ENST00000266542.4
C1RL
complement component 1, r subcomponent-like
chr16_+_90089008 0.39 ENST00000268699.4
GAS8
growth arrest-specific 8
chr2_+_3642545 0.38 ENST00000382062.2
ENST00000236693.7
ENST00000349077.4
COLEC11
collectin sub-family member 11
chr17_+_53342311 0.38 ENST00000226067.5
HLF
hepatic leukemia factor
chr17_+_6347729 0.37 ENST00000572447.1
FAM64A
family with sequence similarity 64, member A
chr7_-_150754935 0.37 ENST00000297518.4
CDK5
cyclin-dependent kinase 5
chr22_+_31518938 0.37 ENST00000412985.1
ENST00000331075.5
ENST00000412277.2
ENST00000420017.1
ENST00000400294.2
ENST00000405300.1
ENST00000404390.3
INPP5J
inositol polyphosphate-5-phosphatase J
chr1_+_27719148 0.37 ENST00000374024.3
GPR3
G protein-coupled receptor 3
chr2_-_25475120 0.36 ENST00000380746.4
ENST00000402667.1
DNMT3A
DNA (cytosine-5-)-methyltransferase 3 alpha
chr1_-_52870059 0.34 ENST00000371566.1
ORC1
origin recognition complex, subunit 1
chr15_-_76304731 0.33 ENST00000394907.3
NRG4
neuregulin 4
chr7_+_140378955 0.33 ENST00000473512.1
ADCK2
aarF domain containing kinase 2
chr12_+_98909260 0.33 ENST00000556029.1
TMPO
thymopoietin
chrX_-_133930285 0.32 ENST00000486347.1
ENST00000343004.5
FAM122B
family with sequence similarity 122B
chr1_-_52870104 0.32 ENST00000371568.3
ORC1
origin recognition complex, subunit 1
chr14_+_24422795 0.31 ENST00000313250.5
ENST00000558263.1
ENST00000543741.2
ENST00000421831.1
ENST00000397073.2
ENST00000308178.8
ENST00000382761.3
ENST00000397075.3
ENST00000397074.3
ENST00000559632.1
ENST00000558581.1
DHRS4
dehydrogenase/reductase (SDR family) member 4
chr3_+_148415571 0.30 ENST00000497524.1
ENST00000349243.3
ENST00000542281.1
ENST00000418473.2
ENST00000404754.2
AGTR1
angiotensin II receptor, type 1
chr5_+_143584814 0.29 ENST00000507359.3
KCTD16
potassium channel tetramerization domain containing 16
chr11_-_62476694 0.28 ENST00000524862.1
BSCL2
Berardinelli-Seip congenital lipodystrophy 2 (seipin)
chr4_+_22999152 0.26 ENST00000511453.1
RP11-412P11.1
RP11-412P11.1
chr7_-_140714739 0.26 ENST00000467334.1
ENST00000324787.5
MRPS33
mitochondrial ribosomal protein S33
chr11_-_62477103 0.25 ENST00000532818.1
BSCL2
Berardinelli-Seip congenital lipodystrophy 2 (seipin)
chr7_-_140714430 0.25 ENST00000393008.3
MRPS33
mitochondrial ribosomal protein S33
chr17_+_7836398 0.25 ENST00000565740.1
CNTROB
centrobin, centrosomal BRCA2 interacting protein
chr18_+_12407895 0.25 ENST00000590956.1
ENST00000336990.4
ENST00000440960.1
ENST00000588729.1
SLMO1
slowmo homolog 1 (Drosophila)
chr16_-_28621353 0.23 ENST00000567512.1
SULT1A1
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
chr11_-_72432950 0.23 ENST00000426523.1
ENST00000429686.1
ARAP1
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
chr1_+_28261533 0.22 ENST00000411604.1
ENST00000373888.4
SMPDL3B
sphingomyelin phosphodiesterase, acid-like 3B
chr1_+_173446405 0.21 ENST00000340385.5
PRDX6
peroxiredoxin 6
chr2_+_13677795 0.21 ENST00000434509.1
AC092635.1
AC092635.1
chr3_-_20227720 0.21 ENST00000412997.1
SGOL1
shugoshin-like 1 (S. pombe)
chr16_-_28608364 0.20 ENST00000533150.1
SULT1A2
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2
chr9_-_25678856 0.20 ENST00000358022.3
TUSC1
tumor suppressor candidate 1
chr20_+_34020827 0.20 ENST00000374375.1
GDF5OS
growth differentiation factor 5 opposite strand
chr1_+_202091980 0.19 ENST00000367282.5
GPR37L1
G protein-coupled receptor 37 like 1
chr1_+_172745006 0.18 ENST00000432694.2
RP1-15D23.2
RP1-15D23.2
chr17_-_40337470 0.18 ENST00000293330.1
HCRT
hypocretin (orexin) neuropeptide precursor
chr8_-_93029865 0.17 ENST00000422361.2
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr17_+_66624280 0.16 ENST00000585484.1
RP11-118B18.1
RP11-118B18.1
chr7_-_141957847 0.16 ENST00000552471.1
ENST00000547058.2
PRSS58
protease, serine, 58
chr11_+_101785727 0.16 ENST00000263468.8
KIAA1377
KIAA1377
chr21_+_34602200 0.15 ENST00000382264.3
ENST00000382241.3
ENST00000404220.3
ENST00000342136.4
IFNAR2
interferon (alpha, beta and omega) receptor 2
chr12_+_54379569 0.15 ENST00000513209.1
RP11-834C11.12
RP11-834C11.12
chr16_+_70328680 0.15 ENST00000563206.1
ENST00000451014.3
ENST00000568625.1
DDX19B
DEAD (Asp-Glu-Ala-Asp) box polypeptide 19B
chr10_+_99344071 0.15 ENST00000370647.4
ENST00000370646.4
HOGA1
4-hydroxy-2-oxoglutarate aldolase 1
chr3_-_43147431 0.14 ENST00000441964.1
POMGNT2
protein O-linked mannose N-acetylglucosaminyltransferase 2 (beta 1,4-)
chr6_-_53013620 0.14 ENST00000259803.7
GCM1
glial cells missing homolog 1 (Drosophila)
chr7_-_81399438 0.14 ENST00000222390.5
HGF
hepatocyte growth factor (hepapoietin A; scatter factor)
chrX_+_15767971 0.14 ENST00000479740.1
ENST00000454127.2
CA5B
carbonic anhydrase VB, mitochondrial
chr7_+_96634850 0.13 ENST00000518156.2
DLX6
distal-less homeobox 6
chr16_-_28621312 0.13 ENST00000314752.7
SULT1A1
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
chr1_+_44444865 0.13 ENST00000372324.1
B4GALT2
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2
chr3_-_157251383 0.13 ENST00000487753.1
ENST00000489602.1
ENST00000461299.1
ENST00000479987.1
VEPH1
ventricular zone expressed PH domain-containing 1
chr2_+_204732487 0.12 ENST00000302823.3
CTLA4
cytotoxic T-lymphocyte-associated protein 4
chr19_+_45165545 0.12 ENST00000592472.1
ENST00000587729.1
ENST00000585657.1
ENST00000592789.1
ENST00000591979.1
CEACAM19
carcinoembryonic antigen-related cell adhesion molecule 19
chr2_+_201997492 0.12 ENST00000494258.1
CFLAR
CASP8 and FADD-like apoptosis regulator
chrX_-_33357558 0.12 ENST00000288447.4
DMD
dystrophin
chr3_-_43147549 0.12 ENST00000344697.2
POMGNT2
protein O-linked mannose N-acetylglucosaminyltransferase 2 (beta 1,4-)
chr2_-_231860596 0.11 ENST00000441063.1
ENST00000434094.1
ENST00000418330.1
ENST00000457803.1
ENST00000414876.1
ENST00000446741.1
ENST00000426904.1
AC105344.2
SPATA3 antisense RNA 1 (head to head)
chr7_+_141490017 0.11 ENST00000247883.4
TAS2R5
taste receptor, type 2, member 5
chr2_+_201997595 0.11 ENST00000470178.2
CFLAR
CASP8 and FADD-like apoptosis regulator
chr2_+_231860830 0.11 ENST00000424440.1
ENST00000452881.1
ENST00000433428.2
ENST00000455816.1
ENST00000440792.1
ENST00000423134.1
SPATA3
spermatogenesis associated 3
chr17_-_45908875 0.10 ENST00000351111.2
ENST00000414011.1
MRPL10
mitochondrial ribosomal protein L10
chr12_-_68647281 0.10 ENST00000328087.4
ENST00000538666.1
IL22
interleukin 22
chr19_-_13044494 0.10 ENST00000593021.1
ENST00000587981.1
ENST00000423140.2
ENST00000314606.4
FARSA
phenylalanyl-tRNA synthetase, alpha subunit
chr3_+_46919235 0.10 ENST00000449590.1
PTH1R
parathyroid hormone 1 receptor
chr12_+_68042495 0.09 ENST00000344096.3
DYRK2
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2
chr14_-_74892805 0.09 ENST00000331628.3
ENST00000554953.1
SYNDIG1L
synapse differentiation inducing 1-like
chr11_+_67171358 0.08 ENST00000526387.1
TBC1D10C
TBC1 domain family, member 10C
chr2_-_159237472 0.08 ENST00000409187.1
CCDC148
coiled-coil domain containing 148
chr11_+_67171548 0.08 ENST00000542590.1
TBC1D10C
TBC1 domain family, member 10C
chr7_-_81399287 0.08 ENST00000354224.6
HGF
hepatocyte growth factor (hepapoietin A; scatter factor)
chr1_-_155904187 0.07 ENST00000368321.3
ENST00000368320.3
KIAA0907
KIAA0907
chr11_-_2323089 0.07 ENST00000456145.2
C11orf21
chromosome 11 open reading frame 21
chr16_-_28621298 0.06 ENST00000566189.1
SULT1A1
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
chr11_+_112130988 0.06 ENST00000595053.1
AP002884.2
LOC100132686 protein; Uncharacterized protein
chr4_+_76481258 0.06 ENST00000311623.4
ENST00000435974.2
C4orf26
chromosome 4 open reading frame 26
chr19_+_12862486 0.06 ENST00000549706.1
BEST2
bestrophin 2
chr12_-_62653903 0.06 ENST00000552075.1
FAM19A2
family with sequence similarity 19 (chemokine (C-C motif)-like), member A2
chr11_-_62477313 0.05 ENST00000464544.1
ENST00000530009.1
BSCL2
Berardinelli-Seip congenital lipodystrophy 2 (seipin)
chr11_+_67171391 0.05 ENST00000312390.5
TBC1D10C
TBC1 domain family, member 10C
chr11_-_2323290 0.05 ENST00000381153.3
C11orf21
chromosome 11 open reading frame 21
chr10_-_99393242 0.05 ENST00000370635.3
ENST00000478953.1
ENST00000335628.3
MORN4
MORN repeat containing 4
chr8_+_102064237 0.05 ENST00000514926.1
RP11-302J23.1
RP11-302J23.1
chr7_-_81399329 0.05 ENST00000453411.1
ENST00000444829.2
HGF
hepatocyte growth factor (hepapoietin A; scatter factor)
chrX_+_149531606 0.04 ENST00000432680.2
MAMLD1
mastermind-like domain containing 1
chr12_-_25801478 0.04 ENST00000540106.1
ENST00000445693.1
ENST00000545543.1
ENST00000542224.1
IFLTD1
intermediate filament tail domain containing 1
chr7_-_81399411 0.04 ENST00000423064.2
HGF
hepatocyte growth factor (hepapoietin A; scatter factor)
chr7_-_81399355 0.04 ENST00000457544.2
HGF
hepatocyte growth factor (hepapoietin A; scatter factor)
chr1_+_207262540 0.04 ENST00000452902.2
C4BPB
complement component 4 binding protein, beta
chr6_+_10634158 0.03 ENST00000379591.3
GCNT6
glucosaminyl (N-acetyl) transferase 6
chr11_+_2323349 0.03 ENST00000381121.3
TSPAN32
tetraspanin 32
chr11_+_17569375 0.03 ENST00000399397.1
OTOG
otogelin
chr12_+_27619743 0.03 ENST00000298876.4
ENST00000416383.1
SMCO2
single-pass membrane protein with coiled-coil domains 2
chr7_+_110731062 0.03 ENST00000308478.5
ENST00000451085.1
ENST00000422987.3
ENST00000421101.1
LRRN3
leucine rich repeat neuronal 3
chr6_+_44191507 0.03 ENST00000371724.1
ENST00000371713.1
SLC29A1
solute carrier family 29 (equilibrative nucleoside transporter), member 1
chr7_-_81399678 0.02 ENST00000412881.1
HGF
hepatocyte growth factor (hepapoietin A; scatter factor)
chr15_-_31393910 0.02 ENST00000397795.2
ENST00000256552.6
ENST00000559179.1
TRPM1
transient receptor potential cation channel, subfamily M, member 1
chr10_+_82297658 0.02 ENST00000339284.2
SH2D4B
SH2 domain containing 4B
chr1_+_207262627 0.02 ENST00000391923.1
C4BPB
complement component 4 binding protein, beta
chr19_+_12862604 0.02 ENST00000553030.1
BEST2
bestrophin 2
chr1_+_207262578 0.02 ENST00000243611.5
ENST00000367076.3
C4BPB
complement component 4 binding protein, beta
chr1_+_11249398 0.01 ENST00000376819.3
ANGPTL7
angiopoietin-like 7
chr9_+_35805527 0.01 ENST00000421267.1
NPR2
natriuretic peptide receptor B/guanylate cyclase B (atrionatriuretic peptide receptor B)
chrX_+_49832231 0.01 ENST00000376108.3
CLCN5
chloride channel, voltage-sensitive 5
chr5_-_147286065 0.01 ENST00000318315.4
ENST00000515291.1
C5orf46
chromosome 5 open reading frame 46
chr11_+_2323236 0.01 ENST00000182290.4
TSPAN32
tetraspanin 32
chr22_-_24093267 0.01 ENST00000341976.3
ZNF70
zinc finger protein 70
chr1_+_155911480 0.01 ENST00000368318.3
RXFP4
relaxin/insulin-like family peptide receptor 4

Network of associatons between targets according to the STRING database.

First level regulatory network of HAND1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 3.8 GO:0071874 cellular response to norepinephrine stimulus(GO:0071874)
0.6 1.9 GO:0045360 regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362)
0.4 4.4 GO:0019344 cysteine biosynthetic process(GO:0019344)
0.3 1.8 GO:0010133 proline catabolic process to glutamate(GO:0010133)
0.2 1.1 GO:0060024 rhythmic synaptic transmission(GO:0060024) positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000969)
0.2 1.1 GO:0051835 positive regulation of synapse structural plasticity(GO:0051835)
0.2 2.9 GO:0071376 response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
0.2 1.8 GO:0007288 sperm axoneme assembly(GO:0007288)
0.2 0.5 GO:0014707 branchiomeric skeletal muscle development(GO:0014707)
0.2 1.7 GO:0034392 negative regulation of smooth muscle cell apoptotic process(GO:0034392)
0.1 0.5 GO:0071934 thiamine transmembrane transport(GO:0071934)
0.1 1.1 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.1 0.3 GO:0086097 phospholipase C-activating angiotensin-activated signaling pathway(GO:0086097)
0.1 0.1 GO:0019470 4-hydroxyproline catabolic process(GO:0019470)
0.1 0.1 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.1 1.7 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.1 0.9 GO:0035860 glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.0 1.0 GO:0075522 IRES-dependent viral translational initiation(GO:0075522)
0.0 0.4 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.0 0.4 GO:0090116 C-5 methylation of cytosine(GO:0090116)
0.0 0.6 GO:0007144 female meiosis I(GO:0007144)
0.0 2.3 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.0 0.4 GO:1904526 regulation of microtubule binding(GO:1904526)
0.0 0.2 GO:0030037 actin filament reorganization involved in cell cycle(GO:0030037)
0.0 1.4 GO:0035162 embryonic hemopoiesis(GO:0035162)
0.0 0.4 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.0 0.4 GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.0 0.8 GO:0070986 left/right axis specification(GO:0070986)
0.0 0.1 GO:0045590 negative regulation of regulatory T cell differentiation(GO:0045590)
0.0 0.2 GO:1902410 mitotic cytokinetic process(GO:1902410)
0.0 0.2 GO:0021940 positive regulation of cerebellar granule cell precursor proliferation(GO:0021940)
0.0 3.0 GO:0098869 cellular oxidant detoxification(GO:0098869)
0.0 0.3 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.0 0.6 GO:0034389 lipid particle organization(GO:0034389)
0.0 0.4 GO:0006068 ethanol catabolic process(GO:0006068)
0.0 0.1 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.0 0.7 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.0 0.1 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.0 0.4 GO:0031115 negative regulation of microtubule polymerization(GO:0031115)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.7 GO:0031089 platelet dense granule lumen(GO:0031089)
0.1 0.4 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.1 0.7 GO:0035032 phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.0 0.7 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0 0.6 GO:0000235 astral microtubule(GO:0000235) aster(GO:0005818)
0.0 0.8 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 3.8 GO:0005604 basement membrane(GO:0005604)
0.0 0.1 GO:0009328 phenylalanine-tRNA ligase complex(GO:0009328)
0.0 0.4 GO:0001741 XY body(GO:0001741)
0.0 0.5 GO:0005763 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 0.1 GO:0016013 syntrophin complex(GO:0016013)
0.0 2.2 GO:0031514 motile cilium(GO:0031514)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 3.8 GO:0031694 alpha-2A adrenergic receptor binding(GO:0031694)
0.7 2.2 GO:0004947 bradykinin receptor activity(GO:0004947)
0.6 1.9 GO:0031731 CCR6 chemokine receptor binding(GO:0031731)
0.4 1.8 GO:0004657 proline dehydrogenase activity(GO:0004657)
0.3 1.7 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.2 4.4 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.2 1.8 GO:0070740 tubulin-glutamic acid ligase activity(GO:0070740)
0.1 0.5 GO:0015403 thiamine uptake transmembrane transporter activity(GO:0015403)
0.1 1.0 GO:1990829 C-rich single-stranded DNA binding(GO:1990829)
0.1 0.3 GO:0000253 3-keto sterol reductase activity(GO:0000253)
0.1 0.3 GO:0001596 angiotensin type I receptor activity(GO:0001596)
0.1 0.9 GO:0016167 glial cell-derived neurotrophic factor receptor activity(GO:0016167)
0.1 3.0 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.1 1.1 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.1 0.3 GO:0097363 protein O-GlcNAc transferase activity(GO:0097363)
0.1 0.4 GO:0047894 flavonol 3-sulfotransferase activity(GO:0047894)
0.0 0.4 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 1.1 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.1 GO:0045518 interleukin-22 receptor binding(GO:0045518)
0.0 0.1 GO:0004461 lactose synthase activity(GO:0004461)
0.0 0.4 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.0 0.4 GO:0052658 inositol-polyphosphate 5-phosphatase activity(GO:0004445) inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658)
0.0 2.9 GO:0004879 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)
0.0 0.1 GO:0004905 type I interferon receptor activity(GO:0004905)
0.0 0.1 GO:0016833 oxo-acid-lyase activity(GO:0016833)
0.0 0.1 GO:0004991 parathyroid hormone receptor activity(GO:0004991)
0.0 0.4 GO:0005537 mannose binding(GO:0005537)
0.0 0.5 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 1.1 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 0.1 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.0 0.2 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 2.9 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.6 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 3.3 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 4.4 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 2.9 REACTOME PIP3 ACTIVATES AKT SIGNALING Genes involved in PIP3 activates AKT signaling
0.0 0.7 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.0 0.7 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 0.1 REACTOME CTLA4 INHIBITORY SIGNALING Genes involved in CTLA4 inhibitory signaling
0.0 1.9 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.4 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 0.6 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0 1.7 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 2.6 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 0.3 REACTOME PI3K EVENTS IN ERBB4 SIGNALING Genes involved in PI3K events in ERBB4 signaling
0.0 1.0 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 0.4 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 0.4 REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.0 0.9 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.4 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling