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SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for HES7_HES5

Z-value: 0.64

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Transcription factors associated with HES7_HES5

Gene Symbol Gene ID Gene Info
HES7
ENSG00000179111.4 hes family bHLH transcription factor 7
HES5
ENSG00000197921.5 hes family bHLH transcription factor 5

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HES5hg19_v2_chr1_-_2461684_24617100.697.4e-04Click!
HES7hg19_v2_chr17_-_8027402_8027432-0.531.6e-02Click!

Activity profile of HES7_HES5 motif

Sorted Z-values of HES7_HES5 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chrX_-_48326764 3.13 ENST00000413668.1
ENST00000441948.1
SLC38A5
solute carrier family 38, member 5
chr13_+_43597269 2.92 ENST00000379221.2
DNAJC15
DnaJ (Hsp40) homolog, subfamily C, member 15
chrX_-_48326683 2.39 ENST00000440085.1
SLC38A5
solute carrier family 38, member 5
chr2_+_27665232 1.69 ENST00000543753.1
ENST00000288873.3
KRTCAP3
keratinocyte associated protein 3
chr19_+_13106383 1.43 ENST00000397661.2
NFIX
nuclear factor I/X (CCAAT-binding transcription factor)
chr2_+_27665289 1.40 ENST00000407293.1
KRTCAP3
keratinocyte associated protein 3
chr3_-_69062764 1.37 ENST00000295571.5
EOGT
EGF domain-specific O-linked N-acetylglucosamine (GlcNAc) transferase
chr3_-_69062790 1.34 ENST00000540955.1
ENST00000456376.1
EOGT
EGF domain-specific O-linked N-acetylglucosamine (GlcNAc) transferase
chr20_+_45523227 1.26 ENST00000327619.5
ENST00000357410.3
EYA2
eyes absent homolog 2 (Drosophila)
chr19_-_19739007 1.22 ENST00000586703.1
ENST00000591042.1
ENST00000407877.3
LPAR2
lysophosphatidic acid receptor 2
chr3_-_69062742 1.14 ENST00000424374.1
EOGT
EGF domain-specific O-linked N-acetylglucosamine (GlcNAc) transferase
chr1_+_16083154 1.12 ENST00000375771.1
FBLIM1
filamin binding LIM protein 1
chr2_-_232328867 1.06 ENST00000453992.1
ENST00000417652.1
ENST00000454824.1
NCL
nucleolin
chr19_+_45281118 1.00 ENST00000270279.3
ENST00000341505.4
CBLC
Cbl proto-oncogene C, E3 ubiquitin protein ligase
chr1_+_150254936 0.96 ENST00000447007.1
ENST00000369095.1
ENST00000369094.1
C1orf51
chromosome 1 open reading frame 51
chr21_-_33985127 0.89 ENST00000290155.3
C21orf59
chromosome 21 open reading frame 59
chr22_+_41777927 0.84 ENST00000266304.4
TEF
thyrotrophic embryonic factor
chr19_-_36822551 0.76 ENST00000591372.1
LINC00665
long intergenic non-protein coding RNA 665
chr19_+_58095501 0.73 ENST00000536878.2
ENST00000597850.1
ENST00000597219.1
ENST00000598689.1
ENST00000599456.1
ENST00000307468.4
ZIK1
zinc finger protein interacting with K protein 1
chr9_+_706842 0.67 ENST00000382293.3
KANK1
KN motif and ankyrin repeat domains 1
chr17_+_30813576 0.62 ENST00000313401.3
CDK5R1
cyclin-dependent kinase 5, regulatory subunit 1 (p35)
chr5_+_112227311 0.60 ENST00000391338.1
ZRSR1
zinc finger (CCCH type), RNA-binding motif and serine/arginine rich 1
chr11_+_45944190 0.60 ENST00000401752.1
ENST00000389968.3
ENST00000325468.5
ENST00000536139.1
GYLTL1B
glycosyltransferase-like 1B
chr6_+_46620676 0.59 ENST00000371347.5
ENST00000411689.2
SLC25A27
solute carrier family 25, member 27
chr4_+_2965307 0.59 ENST00000398051.4
ENST00000503518.2
ENST00000398052.4
ENST00000345167.6
ENST00000504933.1
ENST00000442472.2
GRK4
G protein-coupled receptor kinase 4
chr8_+_38089198 0.58 ENST00000528358.1
ENST00000529642.1
ENST00000532222.1
ENST00000520272.2
DDHD2
DDHD domain containing 2
chr3_-_149510553 0.57 ENST00000462519.2
ENST00000446160.1
ENST00000383050.3
ANKUB1
ankyrin repeat and ubiquitin domain containing 1
chr20_-_44539538 0.56 ENST00000372420.1
PLTP
phospholipid transfer protein
chr3_+_39851170 0.56 ENST00000425621.1
ENST00000396217.3
MYRIP
myosin VIIA and Rab interacting protein
chr20_-_45985464 0.56 ENST00000458360.2
ENST00000262975.4
ZMYND8
zinc finger, MYND-type containing 8
chr6_-_112194484 0.55 ENST00000518295.1
ENST00000484067.2
ENST00000229470.5
ENST00000356013.2
ENST00000368678.4
ENST00000523238.1
ENST00000354650.3
FYN
FYN oncogene related to SRC, FGR, YES
chr4_+_2819883 0.55 ENST00000511747.1
ENST00000503393.2
SH3BP2
SH3-domain binding protein 2
chr2_-_219154715 0.54 ENST00000451181.1
ENST00000429501.1
TMBIM1
transmembrane BAX inhibitor motif containing 1
chrX_+_105969893 0.52 ENST00000255499.2
RNF128
ring finger protein 128, E3 ubiquitin protein ligase
chr5_+_148521381 0.52 ENST00000504238.1
ABLIM3
actin binding LIM protein family, member 3
chr20_-_45985414 0.52 ENST00000461685.1
ENST00000372023.3
ENST00000540497.1
ENST00000435836.1
ENST00000471951.2
ENST00000352431.2
ENST00000396281.4
ENST00000355972.4
ENST00000360911.3
ZMYND8
zinc finger, MYND-type containing 8
chr2_+_201171268 0.50 ENST00000423749.1
ENST00000428692.1
ENST00000457757.1
ENST00000453663.1
SPATS2L
spermatogenesis associated, serine-rich 2-like
chr20_+_35201993 0.50 ENST00000373872.4
TGIF2
TGFB-induced factor homeobox 2
chr19_-_19739321 0.49 ENST00000588461.1
LPAR2
lysophosphatidic acid receptor 2
chr14_+_24641062 0.49 ENST00000311457.3
ENST00000557806.1
ENST00000559919.1
REC8
REC8 meiotic recombination protein
chr6_+_13182751 0.48 ENST00000415087.1
PHACTR1
phosphatase and actin regulator 1
chr4_-_53522703 0.47 ENST00000508499.1
USP46
ubiquitin specific peptidase 46
chr4_+_184427235 0.46 ENST00000412117.1
ENST00000434682.2
ING2
inhibitor of growth family, member 2
chr16_-_21416640 0.46 ENST00000542817.1
NPIPB3
nuclear pore complex interacting protein family, member B3
chr5_+_78532003 0.44 ENST00000396137.4
JMY
junction mediating and regulatory protein, p53 cofactor
chr19_-_53632925 0.42 ENST00000595174.1
ZNF415
zinc finger protein 415
chr1_+_210111534 0.41 ENST00000422431.1
ENST00000534859.1
ENST00000399639.2
ENST00000537238.1
SYT14
synaptotagmin XIV
chr1_+_210111570 0.41 ENST00000367019.1
ENST00000472886.1
SYT14
synaptotagmin XIV
chr11_+_134146635 0.41 ENST00000431683.2
GLB1L3
galactosidase, beta 1-like 3
chr2_-_237123244 0.41 ENST00000447030.1
ASB18
ankyrin repeat and SOCS box containing 18
chr1_-_35497506 0.41 ENST00000317538.5
ENST00000373340.2
ENST00000357182.4
ZMYM6
zinc finger, MYM-type 6
chr5_+_179125907 0.41 ENST00000247461.4
ENST00000452673.2
ENST00000502498.1
ENST00000507307.1
ENST00000513246.1
ENST00000502673.1
ENST00000506654.1
ENST00000512607.2
ENST00000510810.1
CANX
calnexin
chr6_+_46620705 0.39 ENST00000452689.2
SLC25A27
solute carrier family 25, member 27
chr2_+_201171064 0.39 ENST00000451764.2
SPATS2L
spermatogenesis associated, serine-rich 2-like
chr5_+_148521136 0.38 ENST00000506113.1
ABLIM3
actin binding LIM protein family, member 3
chr6_-_114292449 0.38 ENST00000519065.1
HDAC2
histone deacetylase 2
chr5_+_148521046 0.38 ENST00000326685.7
ENST00000356541.3
ENST00000309868.7
ABLIM3
actin binding LIM protein family, member 3
chr3_+_39851094 0.38 ENST00000302541.6
MYRIP
myosin VIIA and Rab interacting protein
chr3_-_189839467 0.37 ENST00000426003.1
LEPREL1
leprecan-like 1
chr20_+_35201857 0.36 ENST00000373874.2
TGIF2
TGFB-induced factor homeobox 2
chr1_+_45140400 0.36 ENST00000453711.1
C1orf228
chromosome 1 open reading frame 228
chr11_-_116968987 0.35 ENST00000434315.2
ENST00000292055.4
ENST00000375288.1
ENST00000542607.1
ENST00000445177.1
ENST00000375300.1
ENST00000446921.2
SIK3
SIK family kinase 3
chr6_-_143771799 0.35 ENST00000237283.8
ADAT2
adenosine deaminase, tRNA-specific 2
chr13_+_115047097 0.35 ENST00000351487.5
UPF3A
UPF3 regulator of nonsense transcripts homolog A (yeast)
chr7_+_5468362 0.34 ENST00000608012.1
RP11-1275H24.3
RP11-1275H24.3
chr10_+_131265443 0.34 ENST00000306010.7
MGMT
O-6-methylguanine-DNA methyltransferase
chr14_+_104689918 0.34 ENST00000553757.1
ENST00000556528.1
ENST00000555282.1
RP11-260M19.2
RP11-260M19.2
chr14_-_36990061 0.33 ENST00000546983.1
NKX2-1
NK2 homeobox 1
chr22_-_30752861 0.33 ENST00000439242.1
ENST00000215793.8
SF3A1
splicing factor 3a, subunit 1, 120kDa
chr2_+_201170770 0.32 ENST00000409988.3
ENST00000409385.1
SPATS2L
spermatogenesis associated, serine-rich 2-like
chrX_+_134124968 0.32 ENST00000330288.4
SMIM10
small integral membrane protein 10
chr16_-_21849091 0.32 ENST00000537951.1
NPIPB4
nuclear pore complex interacting protein family, member B4
chr4_+_94750014 0.31 ENST00000306011.3
ATOH1
atonal homolog 1 (Drosophila)
chr14_-_77737543 0.31 ENST00000298352.4
NGB
neuroglobin
chr5_+_148521454 0.30 ENST00000508983.1
ABLIM3
actin binding LIM protein family, member 3
chr2_+_201170596 0.30 ENST00000439084.1
ENST00000409718.1
SPATS2L
spermatogenesis associated, serine-rich 2-like
chr22_-_43583079 0.29 ENST00000216129.6
TTLL12
tubulin tyrosine ligase-like family, member 12
chr6_-_114292284 0.29 ENST00000520895.1
ENST00000521163.1
ENST00000524334.1
ENST00000368632.2
ENST00000398283.2
HDAC2
histone deacetylase 2
chr16_-_23160591 0.29 ENST00000219689.7
USP31
ubiquitin specific peptidase 31
chr12_-_76953513 0.29 ENST00000547540.1
OSBPL8
oxysterol binding protein-like 8
chr4_+_113152881 0.29 ENST00000274000.5
AP1AR
adaptor-related protein complex 1 associated regulatory protein
chr7_+_148959262 0.28 ENST00000434415.1
ZNF783
zinc finger family member 783
chr22_-_42310570 0.28 ENST00000457093.1
SHISA8
shisa family member 8
chr5_+_95066823 0.28 ENST00000506817.1
ENST00000379982.3
RHOBTB3
Rho-related BTB domain containing 3
chr15_+_81489213 0.28 ENST00000559383.1
ENST00000394660.2
IL16
interleukin 16
chr21_+_42694732 0.27 ENST00000398646.3
FAM3B
family with sequence similarity 3, member B
chr16_-_30237150 0.27 ENST00000543463.1
RP11-347C12.1
Putative NPIP-like protein LOC613037
chr13_+_80055284 0.27 ENST00000218652.7
NDFIP2
Nedd4 family interacting protein 2
chr18_+_11752040 0.27 ENST00000423027.3
GNAL
guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type
chr1_-_45140227 0.26 ENST00000372237.3
TMEM53
transmembrane protein 53
chr19_+_37837185 0.25 ENST00000541583.2
HKR1
HKR1, GLI-Kruppel zinc finger family member
chr19_+_4304685 0.25 ENST00000601006.1
FSD1
fibronectin type III and SPRY domain containing 1
chr6_-_30712313 0.24 ENST00000376377.2
ENST00000259874.5
IER3
immediate early response 3
chr13_+_80055581 0.24 ENST00000487865.1
NDFIP2
Nedd4 family interacting protein 2
chr2_-_132919528 0.24 ENST00000409867.1
ANKRD30BL
ankyrin repeat domain 30B-like
chr4_+_76439665 0.23 ENST00000508105.1
ENST00000311638.3
ENST00000380837.3
ENST00000507556.1
ENST00000504190.1
ENST00000507885.1
ENST00000502620.1
ENST00000514480.1
THAP6
THAP domain containing 6
chr22_+_42095497 0.23 ENST00000401548.3
ENST00000540833.1
ENST00000400107.1
ENST00000300398.4
MEI1
meiosis inhibitor 1
chr1_+_44457441 0.22 ENST00000466180.1
CCDC24
coiled-coil domain containing 24
chr11_-_14380664 0.22 ENST00000545643.1
ENST00000256196.4
RRAS2
related RAS viral (r-ras) oncogene homolog 2
chr2_+_201170703 0.22 ENST00000358677.5
SPATS2L
spermatogenesis associated, serine-rich 2-like
chr8_+_104383759 0.22 ENST00000415886.2
CTHRC1
collagen triple helix repeat containing 1
chr14_+_77647966 0.22 ENST00000554766.1
TMEM63C
transmembrane protein 63C
chr5_-_114598548 0.22 ENST00000379615.3
ENST00000419445.1
PGGT1B
protein geranylgeranyltransferase type I, beta subunit
chr2_+_201171372 0.22 ENST00000409140.3
SPATS2L
spermatogenesis associated, serine-rich 2-like
chr9_+_92219919 0.21 ENST00000252506.6
ENST00000375769.1
GADD45G
growth arrest and DNA-damage-inducible, gamma
chr1_+_44445549 0.21 ENST00000356836.6
B4GALT2
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2
chr2_+_201171242 0.21 ENST00000360760.5
SPATS2L
spermatogenesis associated, serine-rich 2-like
chr4_+_76439649 0.21 ENST00000507557.1
THAP6
THAP domain containing 6
chr21_+_45432174 0.21 ENST00000380221.3
ENST00000291574.4
TRAPPC10
trafficking protein particle complex 10
chr21_-_46330545 0.21 ENST00000320216.6
ENST00000397852.1
ITGB2
integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
chr22_+_18560675 0.21 ENST00000329627.7
PEX26
peroxisomal biogenesis factor 26
chr19_-_4723761 0.20 ENST00000597849.1
ENST00000598800.1
ENST00000602161.1
ENST00000597726.1
ENST00000601130.1
ENST00000262960.9
DPP9
dipeptidyl-peptidase 9
chr17_+_39344697 0.20 ENST00000377723.3
KRTAP9-1
keratin associated protein 9-1
chr5_-_143550241 0.20 ENST00000522203.1
YIPF5
Yip1 domain family, member 5
chr12_-_76953453 0.19 ENST00000549570.1
OSBPL8
oxysterol binding protein-like 8
chr1_+_16083098 0.19 ENST00000496928.2
ENST00000508310.1
FBLIM1
filamin binding LIM protein 1
chr12_+_6644443 0.19 ENST00000396858.1
GAPDH
glyceraldehyde-3-phosphate dehydrogenase
chr4_+_188916918 0.19 ENST00000509524.1
ENST00000326866.4
ZFP42
ZFP42 zinc finger protein
chr20_-_20693131 0.18 ENST00000202677.7
RALGAPA2
Ral GTPase activating protein, alpha subunit 2 (catalytic)
chr8_+_104383728 0.18 ENST00000330295.5
CTHRC1
collagen triple helix repeat containing 1
chr4_+_1003742 0.17 ENST00000398484.2
FGFRL1
fibroblast growth factor receptor-like 1
chr14_-_67826486 0.17 ENST00000555431.1
ENST00000554236.1
ENST00000555474.1
ATP6V1D
ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D
chr14_-_81687197 0.17 ENST00000553612.1
GTF2A1
general transcription factor IIA, 1, 19/37kDa
chr9_-_23821842 0.17 ENST00000544538.1
ELAVL2
ELAV like neuron-specific RNA binding protein 2
chr17_-_1531635 0.17 ENST00000571650.1
SLC43A2
solute carrier family 43 (amino acid system L transporter), member 2
chr18_-_46987000 0.16 ENST00000442713.2
ENST00000269445.6
DYM
dymeclin
chr3_+_38080691 0.16 ENST00000308059.6
ENST00000346219.3
ENST00000452631.2
DLEC1
deleted in lung and esophageal cancer 1
chr12_-_76953573 0.16 ENST00000549646.1
ENST00000550628.1
ENST00000553139.1
ENST00000261183.3
ENST00000393250.4
OSBPL8
oxysterol binding protein-like 8
chr14_-_51297197 0.16 ENST00000382043.4
NIN
ninein (GSK3B interacting protein)
chr15_-_43212836 0.15 ENST00000566931.1
ENST00000564431.1
ENST00000567274.1
TTBK2
tau tubulin kinase 2
chr13_+_115079949 0.15 ENST00000361283.1
CHAMP1
chromosome alignment maintaining phosphoprotein 1
chr12_+_25205155 0.15 ENST00000550945.1
LRMP
lymphoid-restricted membrane protein
chr5_+_143550396 0.15 ENST00000512467.1
KCTD16
potassium channel tetramerization domain containing 16
chrX_-_153523462 0.14 ENST00000361930.3
ENST00000369926.1
TEX28
testis expressed 28
chr17_+_5185552 0.14 ENST00000262477.6
ENST00000408982.2
ENST00000575991.1
ENST00000537505.1
ENST00000546142.2
RABEP1
rabaptin, RAB GTPase binding effector protein 1
chr2_+_201170999 0.14 ENST00000439395.1
ENST00000444012.1
SPATS2L
spermatogenesis associated, serine-rich 2-like
chr16_+_222846 0.14 ENST00000251595.6
ENST00000397806.1
HBA2
hemoglobin, alpha 2
chr2_-_220118631 0.14 ENST00000248437.4
TUBA4A
tubulin, alpha 4a
chr2_+_149402009 0.13 ENST00000457184.1
EPC2
enhancer of polycomb homolog 2 (Drosophila)
chrX_+_152224766 0.13 ENST00000370265.4
ENST00000447306.1
PNMA3
paraneoplastic Ma antigen 3
chr3_+_52719936 0.13 ENST00000418458.1
ENST00000394799.2
GNL3
guanine nucleotide binding protein-like 3 (nucleolar)
chr14_+_67826709 0.13 ENST00000256383.4
EIF2S1
eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa
chr11_-_26593649 0.13 ENST00000455601.2
MUC15
mucin 15, cell surface associated
chr22_-_30987837 0.12 ENST00000335214.6
PES1
pescadillo ribosomal biogenesis factor 1
chr19_-_19049791 0.12 ENST00000594439.1
ENST00000221222.11
HOMER3
homer homolog 3 (Drosophila)
chr11_-_26593677 0.12 ENST00000527569.1
MUC15
mucin 15, cell surface associated
chr7_-_6570817 0.12 ENST00000435185.1
GRID2IP
glutamate receptor, ionotropic, delta 2 (Grid2) interacting protein
chr1_-_220220000 0.12 ENST00000366923.3
EPRS
glutamyl-prolyl-tRNA synthetase
chr14_-_51297360 0.11 ENST00000496749.1
NIN
ninein (GSK3B interacting protein)
chr4_-_52904425 0.11 ENST00000535450.1
SGCB
sarcoglycan, beta (43kDa dystrophin-associated glycoprotein)
chr10_-_71169031 0.11 ENST00000373307.1
TACR2
tachykinin receptor 2
chr11_+_64059464 0.11 ENST00000394525.2
KCNK4
potassium channel, subfamily K, member 4
chr4_-_17783135 0.11 ENST00000265018.3
FAM184B
family with sequence similarity 184, member B
chr1_-_220219775 0.11 ENST00000609181.1
EPRS
glutamyl-prolyl-tRNA synthetase
chr7_+_101460882 0.11 ENST00000292535.7
ENST00000549414.2
ENST00000550008.2
ENST00000546411.2
ENST00000556210.1
CUX1
cut-like homeobox 1
chr10_+_72194585 0.10 ENST00000420338.2
AC022532.1
Uncharacterized protein
chr9_-_139658965 0.10 ENST00000316144.5
LCN15
lipocalin 15
chr15_-_65477637 0.10 ENST00000300107.3
CLPX
caseinolytic mitochondrial matrix peptidase chaperone subunit
chr1_-_109655377 0.10 ENST00000369948.3
C1orf194
chromosome 1 open reading frame 194
chr22_-_30987849 0.10 ENST00000402284.3
ENST00000354694.7
PES1
pescadillo ribosomal biogenesis factor 1
chr1_-_231114542 0.10 ENST00000522821.1
ENST00000366661.4
ENST00000366662.4
ENST00000414259.1
ENST00000522399.1
TTC13
tetratricopeptide repeat domain 13
chr5_+_115298165 0.10 ENST00000357872.4
AQPEP
Aminopeptidase Q
chr9_+_131451480 0.09 ENST00000322030.8
SET
SET nuclear oncogene
chr1_+_44445643 0.09 ENST00000309519.7
B4GALT2
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2
chr2_+_113403434 0.09 ENST00000272542.3
SLC20A1
solute carrier family 20 (phosphate transporter), member 1
chr12_-_6756559 0.09 ENST00000536350.1
ENST00000414226.2
ENST00000546114.1
ACRBP
acrosin binding protein
chr5_+_152870215 0.09 ENST00000518142.1
GRIA1
glutamate receptor, ionotropic, AMPA 1
chr19_-_55954230 0.09 ENST00000376325.4
SHISA7
shisa family member 7
chr12_-_6756609 0.09 ENST00000229243.2
ACRBP
acrosin binding protein
chr12_-_104350898 0.09 ENST00000552940.1
ENST00000547975.1
ENST00000549478.1
ENST00000546540.1
ENST00000546819.1
ENST00000378090.4
ENST00000547945.1
C12orf73
chromosome 12 open reading frame 73
chr15_-_57025728 0.08 ENST00000559352.1
ZNF280D
zinc finger protein 280D
chr1_-_93426998 0.08 ENST00000370310.4
FAM69A
family with sequence similarity 69, member A
chr8_-_142012169 0.08 ENST00000517453.1
PTK2
protein tyrosine kinase 2
chr1_+_28832455 0.08 ENST00000398958.2
ENST00000427469.1
ENST00000434290.1
ENST00000373833.6
RCC1
regulator of chromosome condensation 1
chr17_+_48172639 0.08 ENST00000503176.1
ENST00000503614.1
PDK2
pyruvate dehydrogenase kinase, isozyme 2
chr1_+_150293973 0.07 ENST00000414970.2
ENST00000543398.1
PRPF3
pre-mRNA processing factor 3
chr10_+_180405 0.07 ENST00000439456.1
ENST00000397962.3
ENST00000309776.4
ENST00000381602.4
ZMYND11
zinc finger, MYND-type containing 11
chr2_+_65216462 0.07 ENST00000234256.3
SLC1A4
solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
chr4_+_184580420 0.07 ENST00000334690.6
ENST00000357207.4
TRAPPC11
trafficking protein particle complex 11
chr1_+_150293921 0.07 ENST00000324862.6
PRPF3
pre-mRNA processing factor 3
chr19_-_55458860 0.07 ENST00000592784.1
ENST00000448121.2
ENST00000340844.2
NLRP7
NLR family, pyrin domain containing 7
chr11_+_35684288 0.07 ENST00000299413.5
TRIM44
tripartite motif containing 44
chr1_+_44457261 0.07 ENST00000372318.3
CCDC24
coiled-coil domain containing 24
chr14_+_39735411 0.07 ENST00000603904.1
RP11-407N17.3
cTAGE family member 5 isoform 4
chr21_-_47575481 0.07 ENST00000291670.5
ENST00000397748.1
ENST00000359679.2
ENST00000355384.2
ENST00000397746.3
ENST00000397743.1
FTCD
formimidoyltransferase cyclodeaminase
chr1_-_1293904 0.06 ENST00000309212.6
ENST00000342753.4
ENST00000445648.2
MXRA8
matrix-remodelling associated 8
chr7_-_53879623 0.06 ENST00000380970.2
GS1-179L18.1
GS1-179L18.1
chr22_+_24891210 0.06 ENST00000382760.2
UPB1
ureidopropionase, beta
chr5_+_115298145 0.06 ENST00000395528.2
AQPEP
Aminopeptidase Q
chr22_-_24181174 0.06 ENST00000318109.7
ENST00000406855.3
ENST00000404056.1
ENST00000476077.1
DERL3
derlin 3
chr12_+_52345448 0.06 ENST00000257963.4
ENST00000541224.1
ENST00000426655.2
ENST00000536420.1
ENST00000415850.2
ACVR1B
activin A receptor, type IB
chr5_+_152870106 0.06 ENST00000285900.5
GRIA1
glutamate receptor, ionotropic, AMPA 1
chr5_-_143550159 0.06 ENST00000448443.2
ENST00000513112.1
ENST00000519064.1
ENST00000274496.5
YIPF5
Yip1 domain family, member 5
chr21_-_16374688 0.06 ENST00000411932.1
NRIP1
nuclear receptor interacting protein 1
chr4_-_6692246 0.06 ENST00000499502.2
RP11-539L10.2
RP11-539L10.2
chr4_+_76439095 0.06 ENST00000506261.1
THAP6
THAP domain containing 6
chr22_-_25170683 0.06 ENST00000332271.5
PIWIL3
piwi-like RNA-mediated gene silencing 3
chrX_+_16804544 0.06 ENST00000380122.5
ENST00000398155.4
TXLNG
taxilin gamma
chr22_-_50523760 0.05 ENST00000395876.2
MLC1
megalencephalic leukoencephalopathy with subcortical cysts 1
chr17_+_27046988 0.05 ENST00000496182.1
RPL23A
ribosomal protein L23a

Network of associatons between targets according to the STRING database.

First level regulatory network of HES7_HES5

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.9 GO:1902957 negative regulation of mitochondrial electron transport, NADH to ubiquinone(GO:1902957)
0.3 1.0 GO:0051562 negative regulation of mitochondrial calcium ion concentration(GO:0051562)
0.3 5.5 GO:0015816 glycine transport(GO:0015816)
0.2 0.7 GO:2000393 negative regulation of lamellipodium morphogenesis(GO:2000393)
0.2 0.6 GO:0021722 superior olivary nucleus development(GO:0021718) superior olivary nucleus maturation(GO:0021722)
0.1 1.1 GO:1902952 positive regulation of dendritic spine maintenance(GO:1902952) regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903756) negative regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903758)
0.1 0.6 GO:0042360 vitamin E metabolic process(GO:0042360)
0.1 0.3 GO:0048203 vesicle targeting, trans-Golgi to endosome(GO:0048203)
0.1 0.3 GO:0042668 auditory receptor cell fate determination(GO:0042668)
0.1 0.7 GO:0006344 maintenance of chromatin silencing(GO:0006344)
0.1 0.3 GO:0090222 centrosome-templated microtubule nucleation(GO:0090222)
0.1 0.5 GO:1902045 negative regulation of Fas signaling pathway(GO:1902045)
0.1 0.2 GO:0006433 glutamyl-tRNA aminoacylation(GO:0006424) prolyl-tRNA aminoacylation(GO:0006433)
0.1 1.3 GO:0016576 histone dephosphorylation(GO:0016576)
0.1 0.2 GO:0035606 peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
0.1 0.4 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.1 0.9 GO:0030050 vesicle transport along actin filament(GO:0030050)
0.1 0.2 GO:0051771 negative regulation of nitric-oxide synthase biosynthetic process(GO:0051771)
0.1 0.6 GO:0090204 protein localization to nuclear pore(GO:0090204)
0.1 0.9 GO:0072520 seminiferous tubule development(GO:0072520)
0.1 0.4 GO:0043932 ossification involved in bone remodeling(GO:0043932)
0.0 0.5 GO:0008343 adult feeding behavior(GO:0008343)
0.0 1.0 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.0 0.8 GO:0033623 regulation of integrin activation(GO:0033623)
0.0 1.7 GO:0007202 activation of phospholipase C activity(GO:0007202)
0.0 0.6 GO:0050966 detection of mechanical stimulus involved in sensory perception of pain(GO:0050966) negative regulation of dendritic spine maintenance(GO:1902951)
0.0 0.5 GO:1904352 positive regulation of protein catabolic process in the vacuole(GO:1904352)
0.0 0.1 GO:0050976 detection of mechanical stimulus involved in sensory perception of touch(GO:0050976)
0.0 0.9 GO:0038092 nodal signaling pathway(GO:0038092)
0.0 0.1 GO:1990737 response to manganese-induced endoplasmic reticulum stress(GO:1990737)
0.0 0.3 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
0.0 0.6 GO:0002031 G-protein coupled receptor internalization(GO:0002031)
0.0 0.3 GO:0021759 globus pallidus development(GO:0021759)
0.0 0.1 GO:0033685 negative regulation of luteinizing hormone secretion(GO:0033685)
0.0 0.4 GO:1901838 positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901838)
0.0 0.3 GO:2000781 positive regulation of double-strand break repair(GO:2000781)
0.0 4.0 GO:0006493 protein O-linked glycosylation(GO:0006493)
0.0 0.6 GO:0090141 positive regulation of mitochondrial fission(GO:0090141)
0.0 0.4 GO:0002097 tRNA wobble base modification(GO:0002097)
0.0 0.1 GO:0001543 ovarian follicle rupture(GO:0001543)
0.0 0.2 GO:0099566 regulation of postsynaptic cytosolic calcium ion concentration(GO:0099566)
0.0 0.4 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.0 0.2 GO:0007000 nucleolus organization(GO:0007000)
0.0 0.4 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0 0.1 GO:0019482 beta-alanine metabolic process(GO:0019482)
0.0 0.3 GO:0015671 oxygen transport(GO:0015671)
0.0 0.1 GO:0097084 vascular smooth muscle cell development(GO:0097084)
0.0 0.3 GO:0060628 regulation of ER to Golgi vesicle-mediated transport(GO:0060628)
0.0 0.3 GO:0050930 induction of positive chemotaxis(GO:0050930)
0.0 0.1 GO:0015808 L-alanine transport(GO:0015808)
0.0 0.2 GO:0045141 meiotic telomere clustering(GO:0045141)
0.0 0.2 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.0 1.6 GO:1903955 positive regulation of protein targeting to mitochondrion(GO:1903955)
0.0 0.3 GO:0018146 keratan sulfate biosynthetic process(GO:0018146)
0.0 0.3 GO:0007191 adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.1 0.6 GO:0089701 U2AF(GO:0089701)
0.1 0.5 GO:0034991 nuclear meiotic cohesin complex(GO:0034991)
0.1 0.2 GO:0005953 CAAX-protein geranylgeranyltransferase complex(GO:0005953)
0.1 0.4 GO:0097452 GAIT complex(GO:0097452)
0.0 0.5 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 0.1 GO:0043614 multi-eIF complex(GO:0043614) translation preinitiation complex(GO:0070993) glial limiting end-foot(GO:0097451)
0.0 0.9 GO:0031045 dense core granule(GO:0031045)
0.0 0.2 GO:0044308 axonal spine(GO:0044308)
0.0 0.2 GO:0070545 PeBoW complex(GO:0070545)
0.0 0.2 GO:0034688 integrin alphaM-beta2 complex(GO:0034688)
0.0 0.4 GO:0044233 ER-mitochondrion membrane contact site(GO:0044233)
0.0 0.1 GO:0009368 endopeptidase Clp complex(GO:0009368)
0.0 0.1 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.0 0.6 GO:0097381 photoreceptor disc membrane(GO:0097381)
0.0 2.9 GO:0097517 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 0.5 GO:0032585 multivesicular body membrane(GO:0032585)
0.0 0.3 GO:0036449 microtubule minus-end(GO:0036449)
0.0 0.3 GO:0030008 TRAPP complex(GO:0030008)
0.0 0.5 GO:0016580 Sin3 complex(GO:0016580)
0.0 0.1 GO:0048179 activin receptor complex(GO:0048179)
0.0 0.2 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.0 0.3 GO:0071004 U2 snRNP(GO:0005686) U2-type prespliceosome(GO:0071004)
0.0 0.1 GO:0016012 sarcoglycan complex(GO:0016012)
0.0 1.1 GO:0043198 dendritic shaft(GO:0043198)
0.0 0.3 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 0.1 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 3.8 GO:0016262 protein N-acetylglucosaminyltransferase activity(GO:0016262)
0.4 5.5 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.2 0.6 GO:0016534 cyclin-dependent protein kinase 5 activator activity(GO:0016534)
0.2 0.6 GO:0050254 rhodopsin kinase activity(GO:0050254)
0.2 1.7 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.1 1.1 GO:0044547 DNA topoisomerase binding(GO:0044547)
0.1 0.3 GO:0035650 AP-1 adaptor complex binding(GO:0035650)
0.1 0.3 GO:0004461 lactose synthase activity(GO:0004461)
0.1 0.2 GO:0004827 glutamate-tRNA ligase activity(GO:0004818) proline-tRNA ligase activity(GO:0004827)
0.1 0.2 GO:0004662 CAAX-protein geranylgeranyltransferase activity(GO:0004662)
0.1 0.6 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.1 0.6 GO:0042610 CD8 receptor binding(GO:0042610)
0.0 0.2 GO:0004365 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.0 1.3 GO:0031005 filamin binding(GO:0031005)
0.0 0.3 GO:0008172 S-methyltransferase activity(GO:0008172)
0.0 0.1 GO:0098782 mechanically-gated potassium channel activity(GO:0098782)
0.0 0.4 GO:0005123 death receptor binding(GO:0005123)
0.0 0.4 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.1 GO:0004995 tachykinin receptor activity(GO:0004995)
0.0 0.4 GO:0004565 beta-galactosidase activity(GO:0004565)
0.0 0.4 GO:0004000 adenosine deaminase activity(GO:0004000)
0.0 1.1 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.2 GO:1904315 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.0 0.2 GO:0030369 ICAM-3 receptor activity(GO:0030369)
0.0 0.7 GO:0032041 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0 0.1 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.0 1.5 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 0.3 GO:0005344 oxygen transporter activity(GO:0005344)
0.0 0.6 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 0.3 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.0 0.4 GO:0034185 apolipoprotein binding(GO:0034185)
0.0 0.6 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0 0.2 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.0 0.3 GO:0042609 CD4 receptor binding(GO:0042609)
0.0 0.1 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.0 0.1 GO:0015180 L-alanine transmembrane transporter activity(GO:0015180) alanine transmembrane transporter activity(GO:0022858)
0.0 0.5 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.9 GO:0051018 protein kinase A binding(GO:0051018)
0.0 0.4 GO:0017147 Wnt-protein binding(GO:0017147)
0.0 0.1 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.2 PID REELIN PATHWAY Reelin signaling pathway
0.0 0.3 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 1.8 PID LYSOPHOSPHOLIPID PATHWAY LPA receptor mediated events
0.0 0.4 PID WNT SIGNALING PATHWAY Wnt signaling network

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 5.8 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 1.8 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 0.6 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 0.4 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.6 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 0.9 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 0.3 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.0 0.4 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions