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SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for HESX1

Z-value: 0.54

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Transcription factors associated with HESX1

Gene Symbol Gene ID Gene Info
HESX1
ENSG00000163666.4 HESX homeobox 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HESX1hg19_v2_chr3_-_57260377_57260549-0.213.7e-01Click!

Activity profile of HESX1 motif

Sorted Z-values of HESX1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr16_+_56659687 1.35 ENST00000568293.1
ENST00000330439.6
MT1E
metallothionein 1E
chr3_-_46735155 1.32 ENST00000318962.4
ALS2CL
ALS2 C-terminal like
chr2_-_1748214 0.98 ENST00000433670.1
ENST00000425171.1
ENST00000252804.4
PXDN
peroxidasin homolog (Drosophila)
chr3_-_46735132 0.96 ENST00000415953.1
ALS2CL
ALS2 C-terminal like
chr17_-_39216344 0.93 ENST00000391418.2
KRTAP2-3
keratin associated protein 2-3
chr9_+_132094579 0.92 ENST00000427109.1
RP11-65J3.1
RP11-65J3.1
chr19_-_36004543 0.79 ENST00000339686.3
ENST00000447113.2
ENST00000440396.1
DMKN
dermokine
chrX_+_105969893 0.76 ENST00000255499.2
RNF128
ring finger protein 128, E3 ubiquitin protein ligase
chr1_-_1356628 0.73 ENST00000442470.1
ENST00000537107.1
ANKRD65
ankyrin repeat domain 65
chr20_+_1115821 0.65 ENST00000435720.1
PSMF1
proteasome (prosome, macropain) inhibitor subunit 1 (PI31)
chr3_-_42845922 0.63 ENST00000452906.2
HIGD1A
HIG1 hypoxia inducible domain family, member 1A
chr10_-_101380121 0.60 ENST00000370495.4
SLC25A28
solute carrier family 25 (mitochondrial iron transporter), member 28
chr4_-_77819002 0.58 ENST00000334306.2
SOWAHB
sosondowah ankyrin repeat domain family member B
chr1_+_45265897 0.57 ENST00000372201.4
PLK3
polo-like kinase 3
chr9_-_34376851 0.54 ENST00000297625.7
KIAA1161
KIAA1161
chr19_-_19739321 0.53 ENST00000588461.1
LPAR2
lysophosphatidic acid receptor 2
chr2_-_85829811 0.53 ENST00000306353.3
TMEM150A
transmembrane protein 150A
chr6_+_43739697 0.52 ENST00000230480.6
VEGFA
vascular endothelial growth factor A
chr21_-_38445443 0.52 ENST00000360525.4
PIGP
phosphatidylinositol glycan anchor biosynthesis, class P
chr1_-_40237020 0.49 ENST00000327582.5
OXCT2
3-oxoacid CoA transferase 2
chr11_-_126138808 0.49 ENST00000332118.6
ENST00000532259.1
SRPR
signal recognition particle receptor (docking protein)
chr4_+_144303093 0.47 ENST00000505913.1
GAB1
GRB2-associated binding protein 1
chr6_-_31138439 0.46 ENST00000259915.8
POU5F1
POU class 5 homeobox 1
chr8_-_145060593 0.46 ENST00000313059.5
ENST00000524918.1
ENST00000313028.7
ENST00000525773.1
PARP10
poly (ADP-ribose) polymerase family, member 10
chr4_-_2264015 0.46 ENST00000337190.2
MXD4
MAX dimerization protein 4
chr6_+_31939608 0.45 ENST00000375331.2
ENST00000375333.2
STK19
serine/threonine kinase 19
chr17_+_47572647 0.43 ENST00000172229.3
NGFR
nerve growth factor receptor
chr2_-_74875432 0.42 ENST00000536235.1
ENST00000421985.1
M1AP
meiosis 1 associated protein
chr8_+_71581565 0.42 ENST00000408926.3
ENST00000520030.1
XKR9
XK, Kell blood group complex subunit-related family, member 9
chr16_-_67217844 0.40 ENST00000563902.1
ENST00000561621.1
ENST00000290881.7
KIAA0895L
KIAA0895-like
chr6_-_29600832 0.39 ENST00000377016.4
ENST00000376977.3
ENST00000377034.4
GABBR1
gamma-aminobutyric acid (GABA) B receptor, 1
chrX_-_7895479 0.39 ENST00000381042.4
PNPLA4
patatin-like phospholipase domain containing 4
chr19_+_37407351 0.39 ENST00000455427.2
ENST00000587857.1
ZNF568
zinc finger protein 568
chr6_-_167275991 0.38 ENST00000510118.1
RPS6KA2
ribosomal protein S6 kinase, 90kDa, polypeptide 2
chr6_-_42981651 0.38 ENST00000244711.3
MEA1
male-enhanced antigen 1
chr19_+_37407212 0.38 ENST00000427117.1
ENST00000587130.1
ENST00000333987.7
ENST00000415168.1
ENST00000444991.1
ZNF568
zinc finger protein 568
chr20_-_40247002 0.37 ENST00000373222.3
CHD6
chromodomain helicase DNA binding protein 6
chr2_+_89952792 0.36 ENST00000390265.2
IGKV1D-33
immunoglobulin kappa variable 1D-33
chr3_-_196695692 0.36 ENST00000412723.1
PIGZ
phosphatidylinositol glycan anchor biosynthesis, class Z
chr2_+_32502952 0.34 ENST00000238831.4
YIPF4
Yip1 domain family, member 4
chr22_+_50354104 0.34 ENST00000360612.4
PIM3
pim-3 oncogene
chr14_-_88200641 0.33 ENST00000556168.1
RP11-1152H15.1
RP11-1152H15.1
chr15_+_73976545 0.32 ENST00000318443.5
ENST00000537340.2
ENST00000318424.5
CD276
CD276 molecule
chr19_-_19431298 0.31 ENST00000590439.2
ENST00000334782.5
SUGP1
SURP and G patch domain containing 1
chr3_-_42846021 0.31 ENST00000321331.7
HIGD1A
HIG1 hypoxia inducible domain family, member 1A
chr13_-_108870623 0.31 ENST00000405925.1
LIG4
ligase IV, DNA, ATP-dependent
chr3_+_9944303 0.31 ENST00000421412.1
ENST00000295980.3
IL17RE
interleukin 17 receptor E
chr14_-_91884150 0.30 ENST00000553403.1
CCDC88C
coiled-coil domain containing 88C
chr12_+_6644443 0.30 ENST00000396858.1
GAPDH
glyceraldehyde-3-phosphate dehydrogenase
chr3_+_39851170 0.30 ENST00000425621.1
ENST00000396217.3
MYRIP
myosin VIIA and Rab interacting protein
chr11_+_50257731 0.30 ENST00000525654.1
RP11-347H15.4
RP11-347H15.4
chr11_+_50257784 0.30 ENST00000529219.1
RP11-347H15.4
RP11-347H15.4
chr16_-_70719925 0.30 ENST00000338779.6
MTSS1L
metastasis suppressor 1-like
chr3_+_192958914 0.29 ENST00000264735.2
ENST00000602513.1
HRASLS
HRAS-like suppressor
chr19_+_41698927 0.29 ENST00000310054.4
CYP2S1
cytochrome P450, family 2, subfamily S, polypeptide 1
chr22_+_20105259 0.28 ENST00000416427.1
ENST00000421656.1
ENST00000423859.1
ENST00000418705.2
RANBP1
RAN binding protein 1
chr5_+_52285144 0.28 ENST00000296585.5
ITGA2
integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
chr9_+_21440440 0.27 ENST00000276927.1
IFNA1
interferon, alpha 1
chr9_+_37120536 0.27 ENST00000336755.5
ENST00000534928.1
ENST00000322831.6
ZCCHC7
zinc finger, CCHC domain containing 7
chr6_-_46703069 0.27 ENST00000538237.1
ENST00000274793.7
PLA2G7
phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)
chr19_+_11457232 0.27 ENST00000587531.1
CCDC159
coiled-coil domain containing 159
chr19_+_45312310 0.26 ENST00000589651.1
BCAM
basal cell adhesion molecule (Lutheran blood group)
chr20_+_18269121 0.25 ENST00000377671.3
ENST00000360010.5
ENST00000396026.3
ENST00000402618.2
ENST00000401790.1
ENST00000434018.1
ENST00000538547.1
ENST00000535822.1
ZNF133
zinc finger protein 133
chr6_-_144329384 0.24 ENST00000417959.2
PLAGL1
pleiomorphic adenoma gene-like 1
chr22_+_38453378 0.24 ENST00000437453.1
ENST00000356976.3
PICK1
protein interacting with PRKCA 1
chr1_-_9953295 0.24 ENST00000377258.1
CTNNBIP1
catenin, beta interacting protein 1
chr1_+_11539204 0.24 ENST00000294484.6
ENST00000389575.3
PTCHD2
patched domain containing 2
chr16_+_4784458 0.24 ENST00000590191.1
C16orf71
chromosome 16 open reading frame 71
chr22_+_38453207 0.24 ENST00000404072.3
ENST00000424694.1
PICK1
protein interacting with PRKCA 1
chr1_+_15256230 0.23 ENST00000376028.4
ENST00000400798.2
KAZN
kazrin, periplakin interacting protein
chr6_-_7389942 0.23 ENST00000296742.7
ENST00000502583.1
CAGE1
cancer antigen 1
chr5_-_88180342 0.23 ENST00000502983.1
MEF2C
myocyte enhancer factor 2C
chr12_-_121476750 0.22 ENST00000543677.1
OASL
2'-5'-oligoadenylate synthetase-like
chr20_-_590944 0.22 ENST00000246080.3
TCF15
transcription factor 15 (basic helix-loop-helix)
chr2_-_214017151 0.22 ENST00000452786.1
IKZF2
IKAROS family zinc finger 2 (Helios)
chr11_+_64323156 0.22 ENST00000377585.3
SLC22A11
solute carrier family 22 (organic anion/urate transporter), member 11
chr6_-_46703092 0.22 ENST00000541026.1
PLA2G7
phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)
chr11_+_125774258 0.22 ENST00000263576.6
DDX25
DEAD (Asp-Glu-Ala-Asp) box helicase 25
chr22_+_19419425 0.22 ENST00000333130.3
MRPL40
mitochondrial ribosomal protein L40
chr16_-_57219721 0.21 ENST00000562406.1
ENST00000568671.1
ENST00000567044.1
FAM192A
family with sequence similarity 192, member A
chr18_-_54318353 0.21 ENST00000590954.1
ENST00000540155.1
TXNL1
thioredoxin-like 1
chr3_+_39851094 0.21 ENST00000302541.6
MYRIP
myosin VIIA and Rab interacting protein
chr14_+_78227105 0.21 ENST00000439131.2
ENST00000355883.3
ENST00000557011.1
ENST00000556047.1
C14orf178
chromosome 14 open reading frame 178
chr2_+_186603355 0.21 ENST00000343098.5
FSIP2
fibrous sheath interacting protein 2
chr20_-_5485166 0.21 ENST00000589201.1
ENST00000379053.4
LINC00654
long intergenic non-protein coding RNA 654
chr7_+_72742178 0.21 ENST00000442793.1
ENST00000413573.2
ENST00000252037.4
FKBP6
FK506 binding protein 6, 36kDa
chr9_+_1051481 0.20 ENST00000358146.2
ENST00000259622.6
DMRT2
doublesex and mab-3 related transcription factor 2
chr15_-_82824843 0.20 ENST00000560826.1
ENST00000559187.1
ENST00000330339.7
RPS17
ribosomal protein S17
chr1_-_204165610 0.20 ENST00000367194.4
KISS1
KiSS-1 metastasis-suppressor
chr11_+_64323098 0.20 ENST00000301891.4
SLC22A11
solute carrier family 22 (organic anion/urate transporter), member 11
chr8_+_27182862 0.20 ENST00000521164.1
ENST00000346049.5
PTK2B
protein tyrosine kinase 2 beta
chrX_-_131623043 0.19 ENST00000421707.1
MBNL3
muscleblind-like splicing regulator 3
chr12_+_10331605 0.19 ENST00000298530.3
TMEM52B
transmembrane protein 52B
chr16_+_1662326 0.19 ENST00000397412.3
CRAMP1L
Crm, cramped-like (Drosophila)
chr6_-_83775442 0.19 ENST00000369745.5
UBE3D
ubiquitin protein ligase E3D
chr5_+_40679584 0.19 ENST00000302472.3
PTGER4
prostaglandin E receptor 4 (subtype EP4)
chr10_-_75634326 0.18 ENST00000322635.3
ENST00000444854.2
ENST00000423381.1
ENST00000322680.3
ENST00000394762.2
CAMK2G
calcium/calmodulin-dependent protein kinase II gamma
chr6_-_155635583 0.18 ENST00000367166.4
TFB1M
transcription factor B1, mitochondrial
chr12_+_13197218 0.18 ENST00000197268.8
KIAA1467
KIAA1467
chr20_-_61002584 0.18 ENST00000252998.1
RBBP8NL
RBBP8 N-terminal like
chr18_+_54318616 0.18 ENST00000254442.3
WDR7
WD repeat domain 7
chr11_+_71791359 0.17 ENST00000419228.1
ENST00000435085.1
ENST00000307198.7
ENST00000538413.1
LRTOMT
leucine rich transmembrane and O-methyltransferase domain containing
chr17_-_32906388 0.17 ENST00000357754.1
C17orf102
chromosome 17 open reading frame 102
chr11_-_71791435 0.17 ENST00000351960.6
ENST00000541719.1
ENST00000535111.1
NUMA1
nuclear mitotic apparatus protein 1
chr8_+_79428539 0.17 ENST00000352966.5
PKIA
protein kinase (cAMP-dependent, catalytic) inhibitor alpha
chr10_-_5541525 0.17 ENST00000380332.3
CALML5
calmodulin-like 5
chr4_+_6784401 0.17 ENST00000425103.1
ENST00000307659.5
KIAA0232
KIAA0232
chr8_-_101734170 0.16 ENST00000522387.1
ENST00000518196.1
PABPC1
poly(A) binding protein, cytoplasmic 1
chr13_-_52378231 0.16 ENST00000280056.2
ENST00000444610.2
DHRS12
dehydrogenase/reductase (SDR family) member 12
chr21_-_34852304 0.16 ENST00000542230.2
TMEM50B
transmembrane protein 50B
chr7_-_72742085 0.16 ENST00000333149.2
TRIM50
tripartite motif containing 50
chr1_+_156338993 0.16 ENST00000368249.1
ENST00000368246.2
ENST00000537040.1
ENST00000400992.2
ENST00000255013.3
ENST00000451864.2
RHBG
Rh family, B glycoprotein (gene/pseudogene)
chr19_-_50370799 0.15 ENST00000600910.1
ENST00000322344.3
ENST00000600573.1
PNKP
polynucleotide kinase 3'-phosphatase
chr19_-_38397285 0.15 ENST00000303868.5
WDR87
WD repeat domain 87
chr16_+_46918235 0.15 ENST00000340124.4
GPT2
glutamic pyruvate transaminase (alanine aminotransferase) 2
chr20_-_62587735 0.15 ENST00000354216.6
ENST00000369892.3
ENST00000358711.3
UCKL1
uridine-cytidine kinase 1-like 1
chr1_-_117021430 0.15 ENST00000423907.1
ENST00000434879.1
ENST00000443219.1
RP4-655J12.4
RP4-655J12.4
chr19_+_19496624 0.15 ENST00000494516.2
ENST00000360315.3
ENST00000252577.5
GATAD2A
GATA zinc finger domain containing 2A
chr1_-_165738085 0.15 ENST00000464650.1
ENST00000392129.6
TMCO1
transmembrane and coiled-coil domains 1
chr5_-_171881491 0.15 ENST00000311601.5
SH3PXD2B
SH3 and PX domains 2B
chr1_-_203320617 0.14 ENST00000354955.4
FMOD
fibromodulin
chr2_+_230787213 0.14 ENST00000409992.1
FBXO36
F-box protein 36
chr14_+_61654271 0.14 ENST00000555185.1
ENST00000557294.1
ENST00000556778.1
PRKCH
protein kinase C, eta
chr14_+_45553296 0.14 ENST00000355765.6
ENST00000553605.1
PRPF39
pre-mRNA processing factor 39
chr22_+_44351419 0.14 ENST00000396202.3
SAMM50
SAMM50 sorting and assembly machinery component
chr8_-_101734308 0.14 ENST00000519004.1
ENST00000519363.1
ENST00000520142.1
PABPC1
poly(A) binding protein, cytoplasmic 1
chr13_+_100741269 0.14 ENST00000376286.4
ENST00000376279.3
ENST00000376285.1
PCCA
propionyl CoA carboxylase, alpha polypeptide
chr2_+_90458201 0.14 ENST00000603238.1
CH17-132F21.1
Uncharacterized protein
chr18_-_70535177 0.14 ENST00000327305.6
NETO1
neuropilin (NRP) and tolloid (TLL)-like 1
chr2_+_220495800 0.13 ENST00000413743.1
SLC4A3
solute carrier family 4 (anion exchanger), member 3
chr6_+_41888926 0.13 ENST00000230340.4
BYSL
bystin-like
chr1_+_110009150 0.13 ENST00000401021.3
SYPL2
synaptophysin-like 2
chr19_-_14201507 0.13 ENST00000533683.2
SAMD1
sterile alpha motif domain containing 1
chr2_-_197036289 0.13 ENST00000263955.4
STK17B
serine/threonine kinase 17b
chr21_+_38445539 0.12 ENST00000418766.1
ENST00000450533.1
ENST00000438055.1
ENST00000355666.1
ENST00000540756.1
ENST00000399010.1
TTC3
tetratricopeptide repeat domain 3
chr19_-_50370509 0.12 ENST00000596014.1
PNKP
polynucleotide kinase 3'-phosphatase
chr1_-_109968973 0.12 ENST00000271308.4
ENST00000538610.1
PSMA5
proteasome (prosome, macropain) subunit, alpha type, 5
chr3_+_195943369 0.12 ENST00000296327.5
SLC51A
solute carrier family 51, alpha subunit
chr8_+_109455845 0.12 ENST00000220853.3
EMC2
ER membrane protein complex subunit 2
chr7_+_72742162 0.12 ENST00000431982.2
FKBP6
FK506 binding protein 6, 36kDa
chr11_+_47587129 0.12 ENST00000326656.8
ENST00000326674.9
PTPMT1
protein tyrosine phosphatase, mitochondrial 1
chr19_+_19496728 0.12 ENST00000537887.1
ENST00000417582.2
GATAD2A
GATA zinc finger domain containing 2A
chr1_-_42921915 0.11 ENST00000372565.3
ENST00000433602.2
ZMYND12
zinc finger, MYND-type containing 12
chr3_+_14860469 0.11 ENST00000285046.5
FGD5
FYVE, RhoGEF and PH domain containing 5
chr2_+_230787201 0.11 ENST00000283946.3
FBXO36
F-box protein 36
chr1_+_19967014 0.11 ENST00000428975.1
NBL1
neuroblastoma 1, DAN family BMP antagonist
chr16_-_1661988 0.11 ENST00000426508.2
IFT140
intraflagellar transport 140 homolog (Chlamydomonas)
chr1_+_165600083 0.11 ENST00000367889.3
MGST3
microsomal glutathione S-transferase 3
chr16_-_57219926 0.10 ENST00000566584.1
ENST00000566481.1
ENST00000566077.1
ENST00000564108.1
ENST00000565458.1
ENST00000566681.1
ENST00000567439.1
FAM192A
family with sequence similarity 192, member A
chr16_-_30134441 0.10 ENST00000395200.1
MAPK3
mitogen-activated protein kinase 3
chr11_+_47586982 0.10 ENST00000426530.2
ENST00000534775.1
PTPMT1
protein tyrosine phosphatase, mitochondrial 1
chr4_-_48782259 0.10 ENST00000507711.1
ENST00000358350.4
ENST00000537810.1
ENST00000264319.7
FRYL
FRY-like
chr14_-_106068065 0.10 ENST00000390541.2
IGHE
immunoglobulin heavy constant epsilon
chr22_+_26565440 0.10 ENST00000404234.3
ENST00000529632.2
ENST00000360929.3
ENST00000248933.6
ENST00000343706.4
SEZ6L
seizure related 6 homolog (mouse)-like
chr22_+_44351301 0.10 ENST00000350028.4
SAMM50
SAMM50 sorting and assembly machinery component
chr18_+_54318566 0.10 ENST00000589935.1
ENST00000357574.3
WDR7
WD repeat domain 7
chr12_-_53228079 0.09 ENST00000330553.5
KRT79
keratin 79
chr1_+_11796126 0.09 ENST00000376637.3
AGTRAP
angiotensin II receptor-associated protein
chr1_-_26372602 0.09 ENST00000374278.3
ENST00000374276.3
SLC30A2
solute carrier family 30 (zinc transporter), member 2
chr3_+_138153451 0.09 ENST00000389567.4
ENST00000289135.4
ESYT3
extended synaptotagmin-like protein 3
chr20_-_40247133 0.09 ENST00000373233.3
ENST00000309279.7
CHD6
chromodomain helicase DNA binding protein 6
chr5_+_78532003 0.09 ENST00000396137.4
JMY
junction mediating and regulatory protein, p53 cofactor
chr1_+_47799446 0.09 ENST00000371873.5
CMPK1
cytidine monophosphate (UMP-CMP) kinase 1, cytosolic
chr3_-_51975942 0.09 ENST00000232888.6
RRP9
ribosomal RNA processing 9, small subunit (SSU) processome component, homolog (yeast)
chr7_-_112758589 0.09 ENST00000413744.1
ENST00000439551.1
ENST00000441359.1
LINC00998
long intergenic non-protein coding RNA 998
chr4_+_160203650 0.09 ENST00000514565.1
RAPGEF2
Rap guanine nucleotide exchange factor (GEF) 2
chr17_-_36906058 0.08 ENST00000580830.1
PCGF2
polycomb group ring finger 2
chr8_+_133909919 0.08 ENST00000518505.1
TG
thyroglobulin
chr16_+_4784273 0.08 ENST00000299320.5
ENST00000586724.1
C16orf71
chromosome 16 open reading frame 71
chr15_-_31453359 0.08 ENST00000542188.1
TRPM1
transient receptor potential cation channel, subfamily M, member 1
chr1_+_3614591 0.08 ENST00000378290.4
TP73
tumor protein p73
chr3_-_196695733 0.08 ENST00000443835.1
PIGZ
phosphatidylinositol glycan anchor biosynthesis, class Z
chr7_+_74508372 0.08 ENST00000356115.5
ENST00000430511.2
ENST00000312575.7
GTF2IRD2B
GTF2I repeat domain containing 2B
chr1_-_16302565 0.08 ENST00000537142.1
ENST00000448462.2
ZBTB17
zinc finger and BTB domain containing 17
chr20_-_34117447 0.08 ENST00000246199.2
ENST00000424444.1
ENST00000374345.4
ENST00000444723.1
C20orf173
chromosome 20 open reading frame 173
chr7_-_99679324 0.08 ENST00000292393.5
ENST00000413658.2
ENST00000412947.1
ENST00000441298.1
ENST00000449785.1
ENST00000299667.4
ENST00000424697.1
ZNF3
zinc finger protein 3
chr2_+_234216454 0.07 ENST00000447536.1
ENST00000409110.1
SAG
S-antigen; retina and pineal gland (arrestin)
chr1_+_11796177 0.07 ENST00000400895.2
ENST00000376629.4
ENST00000376627.2
ENST00000314340.5
ENST00000452018.2
ENST00000510878.1
AGTRAP
angiotensin II receptor-associated protein
chr8_-_16035454 0.07 ENST00000355282.2
MSR1
macrophage scavenger receptor 1
chr4_+_15683404 0.07 ENST00000422728.2
FAM200B
family with sequence similarity 200, member B
chr1_-_161337662 0.06 ENST00000367974.1
C1orf192
chromosome 1 open reading frame 192
chr16_-_57219966 0.06 ENST00000565760.1
ENST00000309137.8
ENST00000570184.1
ENST00000562324.1
FAM192A
family with sequence similarity 192, member A
chr19_+_19431490 0.06 ENST00000392313.6
ENST00000262815.8
ENST00000609122.1
MAU2
MAU2 sister chromatid cohesion factor
chr21_-_38445011 0.06 ENST00000464265.1
ENST00000399102.1
PIGP
phosphatidylinositol glycan anchor biosynthesis, class P
chr19_-_39694894 0.06 ENST00000318438.6
SYCN
syncollin
chr11_-_1912084 0.06 ENST00000391480.1
C11orf89
chromosome 11 open reading frame 89
chr19_+_41699135 0.06 ENST00000542619.1
ENST00000600561.1
CYP2S1
cytochrome P450, family 2, subfamily S, polypeptide 1
chr14_-_90798418 0.06 ENST00000354366.3
NRDE2
NRDE-2, necessary for RNA interference, domain containing
chr5_-_176057518 0.06 ENST00000393693.2
SNCB
synuclein, beta
chr4_+_156588350 0.06 ENST00000296518.7
GUCY1A3
guanylate cyclase 1, soluble, alpha 3
chr8_-_97173020 0.06 ENST00000287020.5
GDF6
growth differentiation factor 6
chr11_+_67222818 0.06 ENST00000325656.5
CABP4
calcium binding protein 4
chr5_-_41071392 0.05 ENST00000399564.4
MROH2B
maestro heat-like repeat family member 2B
chr11_+_118443098 0.05 ENST00000392859.3
ENST00000359415.4
ENST00000534182.2
ENST00000264028.4
ARCN1
archain 1
chr1_+_47799542 0.05 ENST00000471289.2
ENST00000450808.2
CMPK1
cytidine monophosphate (UMP-CMP) kinase 1, cytosolic
chr17_-_39258461 0.05 ENST00000440582.1
KRTAP4-16P
keratin associated protein 4-16, pseudogene
chr3_+_158519654 0.05 ENST00000415822.2
ENST00000392813.4
ENST00000264266.8
MFSD1
major facilitator superfamily domain containing 1
chr4_-_144826682 0.05 ENST00000358615.4
ENST00000437468.2
GYPE
glycophorin E (MNS blood group)
chr1_+_169337172 0.05 ENST00000367807.3
ENST00000367808.3
ENST00000329281.2
ENST00000420531.1
BLZF1
basic leucine zipper nuclear factor 1
chr11_-_4414880 0.05 ENST00000254436.7
ENST00000543625.1
TRIM21
tripartite motif containing 21

Network of associatons between targets according to the STRING database.

First level regulatory network of HESX1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0048250 mitochondrial iron ion transport(GO:0048250)
0.2 0.6 GO:0007113 endomitotic cell cycle(GO:0007113)
0.2 0.5 GO:1903572 regulation of protein kinase D signaling(GO:1903570) positive regulation of protein kinase D signaling(GO:1903572)
0.2 0.5 GO:0009786 regulation of asymmetric cell division(GO:0009786)
0.1 0.8 GO:1903575 cornified envelope assembly(GO:1903575)
0.1 0.3 GO:0051102 DNA ligation involved in DNA recombination(GO:0051102)
0.1 0.3 GO:0035606 peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
0.1 0.3 GO:0033341 regulation of collagen binding(GO:0033341)
0.1 0.5 GO:0010847 regulation of chromatin assembly(GO:0010847) protein auto-ADP-ribosylation(GO:0070213)
0.1 0.4 GO:1903588 negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903588)
0.1 0.4 GO:0007060 male meiosis chromosome segregation(GO:0007060)
0.1 0.5 GO:0046469 platelet activating factor metabolic process(GO:0046469)
0.1 0.2 GO:2000417 negative regulation of eosinophil migration(GO:2000417)
0.1 0.5 GO:0046952 ketone body catabolic process(GO:0046952)
0.1 0.5 GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
0.1 0.3 GO:0098502 DNA dephosphorylation(GO:0098502)
0.1 0.8 GO:1904352 positive regulation of protein catabolic process in the vacuole(GO:1904352)
0.1 0.2 GO:0070634 transepithelial ammonium transport(GO:0070634)
0.1 0.2 GO:0009080 alanine metabolic process(GO:0006522) alanine catabolic process(GO:0006524) pyruvate family amino acid metabolic process(GO:0009078) pyruvate family amino acid catabolic process(GO:0009080)
0.0 0.2 GO:0002528 regulation of vascular permeability involved in acute inflammatory response(GO:0002528)
0.0 1.3 GO:0071294 cellular response to zinc ion(GO:0071294)
0.0 0.2 GO:0033686 positive regulation of luteinizing hormone secretion(GO:0033686)
0.0 0.4 GO:0015747 urate transport(GO:0015747)
0.0 0.5 GO:0036091 positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0036091)
0.0 0.3 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.0 0.1 GO:2000657 regulation of apolipoprotein binding(GO:2000656) negative regulation of apolipoprotein binding(GO:2000657)
0.0 0.3 GO:0097396 response to interleukin-17(GO:0097396) cellular response to interleukin-17(GO:0097398)
0.0 0.2 GO:0003185 primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
0.0 0.5 GO:0030050 vesicle transport along actin filament(GO:0030050)
0.0 0.2 GO:0061055 myotome development(GO:0061055)
0.0 0.1 GO:0007181 transforming growth factor beta receptor complex assembly(GO:0007181)
0.0 0.2 GO:2000537 regulation of cGMP-mediated signaling(GO:0010752) regulation of B cell chemotaxis(GO:2000537) positive regulation of B cell chemotaxis(GO:2000538)
0.0 0.1 GO:2000312 regulation of kainate selective glutamate receptor activity(GO:2000312)
0.0 1.0 GO:0042744 hydrogen peroxide catabolic process(GO:0042744)
0.0 0.3 GO:2000623 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.0 0.3 GO:0045078 positive regulation of interferon-gamma biosynthetic process(GO:0045078)
0.0 0.3 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.0 0.5 GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.0 0.1 GO:0019626 short-chain fatty acid catabolic process(GO:0019626)
0.0 0.6 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.0 0.2 GO:0045040 protein import into mitochondrial outer membrane(GO:0045040)
0.0 0.2 GO:1902363 regulation of spindle elongation(GO:0032887) regulation of mitotic spindle elongation(GO:0032888) anastral spindle assembly(GO:0055048) protein localization to spindle pole body(GO:0071988) regulation of protein localization to spindle pole body(GO:1902363) positive regulation of protein localization to spindle pole body(GO:1902365) positive regulation of mitotic spindle elongation(GO:1902846)
0.0 0.1 GO:0038098 sequestering of BMP from receptor via BMP binding(GO:0038098)
0.0 0.2 GO:0044211 CTP salvage(GO:0044211)
0.0 2.2 GO:0007032 endosome organization(GO:0007032)
0.0 0.3 GO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.0 0.4 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.0 0.1 GO:0006207 'de novo' pyrimidine nucleobase biosynthetic process(GO:0006207) pyrimidine nucleobase biosynthetic process(GO:0019856)
0.0 0.1 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.0 0.2 GO:0045198 establishment of epithelial cell apical/basal polarity(GO:0045198)
0.0 0.3 GO:0034587 piRNA metabolic process(GO:0034587)
0.0 0.2 GO:0032049 cardiolipin biosynthetic process(GO:0032049)
0.0 0.1 GO:1900377 negative regulation of melanin biosynthetic process(GO:0048022) negative regulation of secondary metabolite biosynthetic process(GO:1900377)
0.0 0.5 GO:0007202 activation of phospholipase C activity(GO:0007202)
0.0 0.1 GO:0034351 regulation of glial cell apoptotic process(GO:0034350) negative regulation of glial cell apoptotic process(GO:0034351)
0.0 0.3 GO:0002244 hematopoietic progenitor cell differentiation(GO:0002244)
0.0 0.0 GO:0035408 histone H3-T6 phosphorylation(GO:0035408)
0.0 0.0 GO:0090086 negative regulation of protein deubiquitination(GO:0090086)
0.0 0.1 GO:0002051 osteoblast fate commitment(GO:0002051)
0.0 0.1 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.0 1.6 GO:0061418 regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061418)
0.0 0.5 GO:0035728 response to hepatocyte growth factor(GO:0035728)
0.0 0.0 GO:0043605 cellular amide catabolic process(GO:0043605)
0.0 0.4 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
0.1 0.3 GO:0005958 DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958)
0.0 0.3 GO:0034666 integrin alpha2-beta1 complex(GO:0034666)
0.0 0.6 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 0.3 GO:0097452 GAIT complex(GO:0097452)
0.0 0.1 GO:0035841 new growing cell tip(GO:0035841)
0.0 0.2 GO:0055028 cortical microtubule(GO:0055028)
0.0 0.1 GO:0030427 site of polarized growth(GO:0030427)
0.0 0.2 GO:0016235 aggresome(GO:0016235)
0.0 0.6 GO:0034362 low-density lipoprotein particle(GO:0034362)
0.0 0.6 GO:0005839 proteasome core complex(GO:0005839)
0.0 0.5 GO:0031045 dense core granule(GO:0031045)
0.0 0.2 GO:0098799 outer mitochondrial membrane protein complex(GO:0098799)
0.0 0.1 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.0 0.0 GO:0001534 radial spoke(GO:0001534)
0.0 0.5 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 0.2 GO:0033391 chromatoid body(GO:0033391)
0.0 1.0 GO:0045095 keratin filament(GO:0045095)
0.0 0.2 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.0 0.1 GO:0000243 commitment complex(GO:0000243)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.0 GO:0005152 interleukin-1 receptor antagonist activity(GO:0005152)
0.1 0.5 GO:0008260 3-oxoacid CoA-transferase activity(GO:0008260)
0.1 0.4 GO:0000026 alpha-1,2-mannosyltransferase activity(GO:0000026)
0.1 0.5 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.1 0.4 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.1 0.4 GO:0050253 retinyl-palmitate esterase activity(GO:0050253)
0.1 0.3 GO:0043891 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.1 0.3 GO:0051734 ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
0.1 0.6 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0 0.5 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.0 0.1 GO:0030627 pre-mRNA 5'-splice site binding(GO:0030627)
0.0 0.5 GO:0003847 1-alkyl-2-acetylglycerophosphocholine esterase activity(GO:0003847)
0.0 0.6 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.4 GO:1901702 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.0 0.1 GO:0009041 uridylate kinase activity(GO:0009041)
0.0 0.3 GO:0098639 collagen binding involved in cell-matrix adhesion(GO:0098639)
0.0 0.3 GO:0005132 type I interferon receptor binding(GO:0005132)
0.0 0.4 GO:0048406 nerve growth factor binding(GO:0048406)
0.0 0.2 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.0 0.3 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.0 0.2 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.0 0.1 GO:0005055 laminin receptor activity(GO:0005055)
0.0 0.6 GO:0005381 iron ion transmembrane transporter activity(GO:0005381)
0.0 2.3 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.3 GO:0003910 DNA ligase (ATP) activity(GO:0003910)
0.0 0.2 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.0 0.7 GO:0035198 miRNA binding(GO:0035198)
0.0 0.1 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.0 0.2 GO:0016206 catechol O-methyltransferase activity(GO:0016206)
0.0 0.7 GO:0070628 proteasome binding(GO:0070628)
0.0 0.2 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.0 0.2 GO:0004849 uridine kinase activity(GO:0004849)
0.0 0.2 GO:0047134 protein-disulfide reductase activity(GO:0047134)
0.0 0.1 GO:0002046 opsin binding(GO:0002046)
0.0 0.3 GO:0008494 translation activator activity(GO:0008494)
0.0 0.2 GO:0004439 phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity(GO:0004439)
0.0 0.1 GO:0034511 U3 snoRNA binding(GO:0034511)
0.0 0.1 GO:0009374 biotin carboxylase activity(GO:0004075) biotin binding(GO:0009374)
0.0 0.5 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 0.1 GO:0047288 monosialoganglioside sialyltransferase activity(GO:0047288)
0.0 0.2 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 0.6 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 0.4 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0 0.3 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 0.9 SIG PIP3 SIGNALING IN B LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 REACTOME REGULATED PROTEOLYSIS OF P75NTR Genes involved in Regulated proteolysis of p75NTR
0.0 0.5 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.5 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 0.4 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.0 0.6 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.4 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 0.3 REACTOME INTEGRATION OF PROVIRUS Genes involved in Integration of provirus
0.0 0.2 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.0 0.3 REACTOME LATE PHASE OF HIV LIFE CYCLE Genes involved in Late Phase of HIV Life Cycle
0.0 0.3 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.0 0.5 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0 0.5 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR