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SARS-CoV-2 Analysis Results (GEO series: GSE147507)
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Results for HINFP
Z-value: 0.91
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Transcription factors associated with HINFP
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| HINFP | hg19_v2_chr11_+_118992269_118992334 | -0.09 | 7.1e-01 | Click! |
Network of associatons between targets according to the STRING database.
First level regulatory network of HINFP
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.9 | 8.2 | GO:0021840 | directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842) |
| 0.9 | 4.5 | GO:0016185 | synaptic vesicle budding from presynaptic endocytic zone membrane(GO:0016185) |
| 0.4 | 3.2 | GO:1990034 | cellular response to corticosterone stimulus(GO:0071386) calcium ion export from cell(GO:1990034) |
| 0.2 | 3.2 | GO:0030091 | protein repair(GO:0030091) |
| 0.3 | 2.7 | GO:0035965 | cardiolipin acyl-chain remodeling(GO:0035965) |
| 0.8 | 2.4 | GO:0042660 | positive regulation of cell fate specification(GO:0042660) |
| 0.0 | 2.4 | GO:0007099 | centriole replication(GO:0007099) |
| 0.7 | 2.2 | GO:0009786 | regulation of asymmetric cell division(GO:0009786) |
| 0.4 | 2.2 | GO:0042699 | follicle-stimulating hormone signaling pathway(GO:0042699) |
| 0.6 | 1.9 | GO:0050760 | negative regulation of thymidylate synthase biosynthetic process(GO:0050760) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 8.2 | GO:0030673 | axolemma(GO:0030673) |
| 0.1 | 4.5 | GO:0001917 | photoreceptor inner segment(GO:0001917) |
| 0.1 | 3.2 | GO:0032591 | dendritic spine membrane(GO:0032591) |
| 0.1 | 2.7 | GO:0005682 | U5 snRNP(GO:0005682) |
| 0.2 | 2.2 | GO:0072687 | meiotic spindle(GO:0072687) |
| 0.1 | 2.1 | GO:0031143 | pseudopodium(GO:0031143) |
| 0.5 | 2.0 | GO:0031523 | Myb complex(GO:0031523) |
| 0.2 | 1.9 | GO:1990812 | growth cone filopodium(GO:1990812) |
| 0.1 | 1.7 | GO:0097418 | neurofibrillary tangle(GO:0097418) |
| 0.0 | 1.7 | GO:0000145 | exocyst(GO:0000145) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.7 | 8.2 | GO:0005176 | ErbB-2 class receptor binding(GO:0005176) |
| 0.0 | 5.8 | GO:0008017 | microtubule binding(GO:0008017) |
| 0.1 | 3.8 | GO:0005388 | calcium-transporting ATPase activity(GO:0005388) |
| 0.1 | 3.6 | GO:0003841 | 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841) |
| 0.5 | 3.2 | GO:0033743 | peptide-methionine (R)-S-oxide reductase activity(GO:0033743) |
| 0.0 | 2.7 | GO:0061631 | ubiquitin conjugating enzyme activity(GO:0061631) |
| 0.1 | 2.4 | GO:0005104 | fibroblast growth factor receptor binding(GO:0005104) |
| 0.7 | 2.2 | GO:0031896 | V2 vasopressin receptor binding(GO:0031896) |
| 0.0 | 2.2 | GO:0005516 | calmodulin binding(GO:0005516) |
| 0.2 | 1.9 | GO:0042577 | lipid phosphatase activity(GO:0042577) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 8.2 | PID ERBB NETWORK PATHWAY | ErbB receptor signaling network |
| 0.1 | 6.4 | PID IL8 CXCR1 PATHWAY | IL8- and CXCR1-mediated signaling events |
| 0.1 | 3.8 | PID NECTIN PATHWAY | Nectin adhesion pathway |
| 0.0 | 3.7 | PID CMYB PATHWAY | C-MYB transcription factor network |
| 0.0 | 2.4 | PID GLYPICAN 1PATHWAY | Glypican 1 network |
| 0.0 | 2.2 | PID ERA GENOMIC PATHWAY | Validated nuclear estrogen receptor alpha network |
| 0.0 | 1.5 | PID DELTA NP63 PATHWAY | Validated transcriptional targets of deltaNp63 isoforms |
| 0.0 | 1.5 | PID PLK1 PATHWAY | PLK1 signaling events |
| 0.0 | 1.4 | PID ARF6 TRAFFICKING PATHWAY | Arf6 trafficking events |
| 0.0 | 1.4 | PID E2F PATHWAY | E2F transcription factor network |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 8.2 | REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING | Genes involved in Downregulation of ERBB2:ERBB3 signaling |
| 0.2 | 4.5 | REACTOME GAP JUNCTION DEGRADATION | Genes involved in Gap junction degradation |
| 0.1 | 3.8 | REACTOME ADHERENS JUNCTIONS INTERACTIONS | Genes involved in Adherens junctions interactions |
| 0.1 | 3.6 | REACTOME SYNTHESIS OF PA | Genes involved in Synthesis of PA |
| 0.1 | 2.4 | REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1 | Genes involved in Signaling by activated point mutants of FGFR1 |
| 0.0 | 2.3 | REACTOME KINESINS | Genes involved in Kinesins |
| 0.0 | 2.2 | REACTOME LYSOSOME VESICLE BIOGENESIS | Genes involved in Lysosome Vesicle Biogenesis |
| 0.0 | 1.9 | REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE | Genes involved in Synthesis of PIPs at the plasma membrane |
| 0.0 | 1.6 | REACTOME NCAM1 INTERACTIONS | Genes involved in NCAM1 interactions |
| 0.1 | 1.5 | REACTOME PYRIMIDINE CATABOLISM | Genes involved in Pyrimidine catabolism |