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SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for HMX1

Z-value: 0.73

Motif logo

Transcription factors associated with HMX1

Gene Symbol Gene ID Gene Info
ENSG00000215612.5 H6 family homeobox 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HMX1hg19_v2_chr4_-_8873531_8873543-0.243.1e-01Click!

Activity profile of HMX1 motif

Sorted Z-values of HMX1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr17_-_78450398 1.36 ENST00000306773.4
neuronal pentraxin I
chr10_-_99531709 1.05 ENST00000266066.3
secreted frizzled-related protein 5
chr15_+_33010175 0.85 ENST00000300177.4
ENST00000560677.1
ENST00000560830.1
gremlin 1, DAN family BMP antagonist
chr1_-_201476220 0.82 ENST00000526723.1
ENST00000524951.1
cysteine and glycine-rich protein 1
chr8_-_26371608 0.79 ENST00000522362.2
paraneoplastic Ma antigen 2
chr8_+_38854368 0.77 ENST00000466936.1
ADAM metallopeptidase domain 9
chr14_+_31343747 0.69 ENST00000216361.4
ENST00000396618.3
ENST00000475087.1
cochlin
chr5_-_58335281 0.67 ENST00000358923.6
phosphodiesterase 4D, cAMP-specific
chr2_+_30454390 0.64 ENST00000395323.3
ENST00000406087.1
ENST00000404397.1
limb bud and heart development
chr11_+_66624527 0.63 ENST00000393952.3
leucine rich repeat and fibronectin type III domain containing 4
chr14_+_31343951 0.61 ENST00000556908.1
ENST00000555881.1
ENST00000460581.2
cochlin
chr12_-_49259643 0.61 ENST00000309739.5
Rho family GTPase 1
chr22_-_39268192 0.59 ENST00000216083.6
chromobox homolog 6
chr19_+_41305612 0.59 ENST00000594380.1
ENST00000593397.1
ENST00000601733.1
egl-9 family hypoxia-inducible factor 2
chr3_-_13461807 0.57 ENST00000254508.5
nucleoporin 210kDa
chr16_+_50280020 0.55 ENST00000564965.1
adenylate cyclase 7
chr8_+_32406137 0.55 ENST00000521670.1
neuregulin 1
chr12_-_16035195 0.55 ENST00000535752.1
epidermal growth factor receptor pathway substrate 8
chr16_+_88872176 0.53 ENST00000569140.1
chromatin licensing and DNA replication factor 1
chr19_+_41305330 0.53 ENST00000593972.1
egl-9 family hypoxia-inducible factor 2
chr16_+_83986827 0.51 ENST00000393306.1
ENST00000565123.1
oxidative stress induced growth inhibitor 1
chr8_+_98881268 0.51 ENST00000254898.5
ENST00000524308.1
ENST00000522025.2
matrilin 2
chr8_-_67525524 0.50 ENST00000517885.1
v-myb avian myeloblastosis viral oncogene homolog-like 1
chr16_-_70713928 0.49 ENST00000576338.1
metastasis suppressor 1-like
chr5_-_37371163 0.49 ENST00000513532.1
nucleoporin 155kDa
chr8_+_145438870 0.48 ENST00000527931.1
family with sequence similarity 203, member B
chr7_-_752577 0.48 ENST00000544935.1
ENST00000430040.1
ENST00000456696.2
ENST00000406797.1
protein kinase, cAMP-dependent, regulatory, type I, beta
chr19_+_41305740 0.47 ENST00000596517.1
egl-9 family hypoxia-inducible factor 2
chr6_+_33359582 0.47 ENST00000450504.1
kinesin family member C1
chr2_-_220436248 0.47 ENST00000265318.4
obscurin-like 1
chr9_-_74525847 0.47 ENST00000377041.2
abhydrolase domain containing 17B
chr22_-_41677625 0.46 ENST00000452543.1
ENST00000418067.1
Ran GTPase activating protein 1
chrX_-_153599578 0.45 ENST00000360319.4
ENST00000344736.4
filamin A, alpha
chr9_-_131940526 0.45 ENST00000372491.2
immediate early response 5-like
chr1_-_201476274 0.44 ENST00000340006.2
cysteine and glycine-rich protein 1
chr8_-_67525473 0.43 ENST00000522677.3
v-myb avian myeloblastosis viral oncogene homolog-like 1
chrX_+_69509927 0.43 ENST00000374403.3
kinesin family member 4A
chr19_+_41305627 0.43 ENST00000593525.1
egl-9 family hypoxia-inducible factor 2
chr21_+_46875424 0.41 ENST00000359759.4
collagen, type XVIII, alpha 1
chr21_+_46875395 0.41 ENST00000355480.5
collagen, type XVIII, alpha 1
chr8_+_32406179 0.41 ENST00000405005.3
neuregulin 1
chr1_+_95583479 0.41 ENST00000455656.1
ENST00000604534.1
transmembrane protein 56
TMEM56-RWDD3 readthrough
chrX_-_20284733 0.40 ENST00000438357.1
ribosomal protein S6 kinase, 90kDa, polypeptide 3
chr15_-_75748143 0.40 ENST00000568431.1
ENST00000568309.1
ENST00000568190.1
ENST00000570115.1
ENST00000564778.1
SIN3 transcription regulator family member A
chr16_+_11439286 0.39 ENST00000312499.5
ENST00000576027.1
RecQ mediated genome instability 2
chr2_-_175462934 0.39 ENST00000392546.2
ENST00000436221.1
WAS/WASL interacting protein family, member 1
chr11_+_43702322 0.37 ENST00000395700.4
hydroxysteroid (17-beta) dehydrogenase 12
chr17_+_79679299 0.37 ENST00000331531.5
solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10
chr17_+_77751931 0.37 ENST00000310942.4
ENST00000269399.5
chromobox homolog 2
chr9_+_116263778 0.36 ENST00000394646.3
regulator of G-protein signaling 3
chr17_-_73874654 0.36 ENST00000254816.2
tripartite motif containing 47
chr12_-_49365501 0.36 ENST00000403957.1
ENST00000301061.4
wingless-type MMTV integration site family, member 10B
chr17_+_40440094 0.36 ENST00000546010.2
signal transducer and activator of transcription 5A
chr11_+_60699222 0.35 ENST00000536409.1
transmembrane protein 132A
chr5_-_172662303 0.35 ENST00000517440.1
ENST00000329198.4
NK2 homeobox 5
chr9_+_116263639 0.34 ENST00000343817.5
regulator of G-protein signaling 3
chr7_-_156685841 0.34 ENST00000354505.4
ENST00000540390.1
limb development membrane protein 1
chr2_-_220435963 0.34 ENST00000373876.1
ENST00000404537.1
ENST00000603926.1
ENST00000373873.4
ENST00000289656.3
obscurin-like 1
chr19_+_41305085 0.32 ENST00000303961.4
egl-9 family hypoxia-inducible factor 2
chr3_+_57994127 0.32 ENST00000490882.1
ENST00000295956.4
ENST00000358537.3
ENST00000429972.2
ENST00000348383.5
ENST00000357272.4
filamin B, beta
chr17_+_79679369 0.32 ENST00000350690.5
solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10
chr2_-_175462456 0.31 ENST00000409891.1
ENST00000410117.1
WAS/WASL interacting protein family, member 1
chr3_+_20081515 0.31 ENST00000263754.4
K(lysine) acetyltransferase 2B
chr1_+_178994939 0.31 ENST00000440702.1
family with sequence similarity 20, member B
chr3_-_52312337 0.31 ENST00000469000.1
WD repeat domain 82
chr3_+_69788576 0.31 ENST00000352241.4
ENST00000448226.2
microphthalmia-associated transcription factor
chr11_+_59522837 0.30 ENST00000437946.2
syntaxin 3
chr7_-_156803329 0.30 ENST00000252971.6
motor neuron and pancreas homeobox 1
chr12_-_15374343 0.30 ENST00000256953.2
ENST00000546331.1
RAS-like, estrogen-regulated, growth inhibitor
chr11_-_17035943 0.30 ENST00000355661.3
ENST00000532079.1
ENST00000448080.2
ENST00000531066.1
pleckstrin homology domain containing, family A member 7
chr11_-_19262486 0.30 ENST00000250024.4
E2F transcription factor 8
chr5_-_172662230 0.29 ENST00000424406.2
NK2 homeobox 5
chr3_-_107941209 0.29 ENST00000492106.1
intraflagellar transport 57 homolog (Chlamydomonas)
chr3_-_138553779 0.28 ENST00000461451.1
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
chr15_-_90198659 0.28 ENST00000394412.3
kinesin family member 7
chr17_-_8534031 0.27 ENST00000411957.1
ENST00000396239.1
ENST00000379980.4
myosin, heavy chain 10, non-muscle
chr9_-_26892765 0.27 ENST00000520187.1
ENST00000333916.5
caspase activity and apoptosis inhibitor 1
chrX_-_153285251 0.27 ENST00000444230.1
ENST00000393682.1
ENST00000393687.2
ENST00000429936.2
ENST00000369974.2
interleukin-1 receptor-associated kinase 1
chr12_+_125478241 0.27 ENST00000341446.8
BRI3 binding protein
chr18_+_11981547 0.27 ENST00000588927.1
inositol(myo)-1(or 4)-monophosphatase 2
chr7_+_130131907 0.27 ENST00000223215.4
ENST00000437945.1
mesoderm specific transcript
chr14_-_51561784 0.27 ENST00000360392.4
tripartite motif containing 9
chr9_+_137967268 0.27 ENST00000371799.4
ENST00000277415.11
olfactomedin 1
chr18_+_11981427 0.26 ENST00000269159.3
inositol(myo)-1(or 4)-monophosphatase 2
chr2_-_167232484 0.26 ENST00000375387.4
ENST00000303354.6
ENST00000409672.1
sodium channel, voltage-gated, type IX, alpha subunit
chr19_+_41305406 0.26 ENST00000406058.2
ENST00000593726.1
egl-9 family hypoxia-inducible factor 2
chr11_+_1411503 0.26 ENST00000526678.1
BR serine/threonine kinase 2
chr1_-_41328018 0.26 ENST00000372638.2
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 4
chr17_+_79213039 0.26 ENST00000431388.2
chromosome 17 open reading frame 89
chr17_-_8534067 0.26 ENST00000360416.3
ENST00000269243.4
myosin, heavy chain 10, non-muscle
chr8_+_120428546 0.26 ENST00000259526.3
nephroblastoma overexpressed
chr2_+_27346666 0.26 ENST00000316470.4
ENST00000416071.1
abhydrolase domain containing 1
chr16_+_85645007 0.25 ENST00000405402.2
Gse1 coiled-coil protein
chr2_-_27341966 0.25 ENST00000402394.1
ENST00000402550.1
ENST00000260595.5
cell growth regulator with EF-hand domain 1
chr5_-_130970723 0.25 ENST00000308008.6
ENST00000296859.6
ENST00000507093.1
ENST00000510071.1
ENST00000509018.1
ENST00000307984.5
Rap guanine nucleotide exchange factor (GEF) 6
chr17_-_47755338 0.25 ENST00000508805.1
ENST00000515508.2
ENST00000451526.2
ENST00000507970.1
speckle-type POZ protein
chr8_+_72755796 0.25 ENST00000524152.1
Protein LOC100132891; cDNA FLJ53548
chrX_-_153285395 0.24 ENST00000369980.3
interleukin-1 receptor-associated kinase 1
chr9_-_98189055 0.24 ENST00000433644.2
RP11-435O5.2
chr11_+_105948216 0.24 ENST00000278618.4
aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase
chr3_+_151986709 0.24 ENST00000495875.2
ENST00000493459.1
ENST00000324210.5
ENST00000459747.1
muscleblind-like splicing regulator 1
chr16_-_70712229 0.23 ENST00000562883.2
metastasis suppressor 1-like
chr22_-_39096925 0.23 ENST00000456626.1
ENST00000412832.1
Josephin domain containing 1
chr5_-_172662197 0.23 ENST00000521848.1
NK2 homeobox 5
chr19_-_10687948 0.23 ENST00000592285.1
adaptor-related protein complex 1, mu 2 subunit
chr4_+_83956312 0.22 ENST00000509317.1
ENST00000503682.1
ENST00000511653.1
COP9 signalosome subunit 4
chr22_-_39096981 0.22 ENST00000427389.1
Josephin domain containing 1
chr2_-_20550416 0.22 ENST00000403432.1
ENST00000424110.1
pumilio RNA-binding family member 2
chr19_-_10341948 0.22 ENST00000590320.1
ENST00000592342.1
ENST00000588952.1
sphingosine-1-phosphate receptor 2
DNA (cytosine-5-)-methyltransferase 1
chr6_+_4773205 0.22 ENST00000440139.1
chromodomain protein, Y-like
chr17_+_38465441 0.22 ENST00000577646.1
ENST00000254066.5
retinoic acid receptor, alpha
chr20_+_21284416 0.22 ENST00000539513.1
5'-3' exoribonuclease 2
chr9_+_137967366 0.21 ENST00000252854.4
olfactomedin 1
chr9_-_126692386 0.21 ENST00000373624.2
ENST00000394219.3
ENST00000373620.3
ENST00000394215.2
ENST00000373618.1
DENN/MADD domain containing 1A
chr5_-_37371278 0.21 ENST00000231498.3
nucleoporin 155kDa
chr8_+_38854418 0.21 ENST00000481513.1
ENST00000487273.2
ADAM metallopeptidase domain 9
chr6_-_8102714 0.21 ENST00000502429.1
ENST00000429723.2
ENST00000507463.1
ENST00000379715.5
eukaryotic translation elongation factor 1 epsilon 1
chr8_-_103876340 0.21 ENST00000518353.1
antizyme inhibitor 1
chr17_-_47755436 0.21 ENST00000505581.1
ENST00000514121.1
ENST00000393328.2
ENST00000509079.1
ENST00000393331.3
ENST00000347630.2
ENST00000504102.1
speckle-type POZ protein
chr17_+_19912640 0.21 ENST00000395527.4
ENST00000583482.2
ENST00000583528.1
ENST00000583463.1
sperm antigen with calponin homology and coiled-coil domains 1
chr20_+_47538357 0.20 ENST00000371917.4
ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited)
chr14_+_56584414 0.20 ENST00000559044.1
pellino E3 ubiquitin protein ligase family member 2
chr19_+_41313017 0.20 ENST00000595621.1
ENST00000595051.1
egl-9 family hypoxia-inducible factor 2
chr2_-_20550382 0.20 ENST00000536417.1
pumilio RNA-binding family member 2
chr4_-_141348999 0.20 ENST00000325617.5
calmegin
chr16_-_20753114 0.20 ENST00000396083.2
THUMP domain containing 1
chr19_-_46285736 0.20 ENST00000291270.4
ENST00000447742.2
ENST00000354227.5
dystrophia myotonica-protein kinase
chrX_-_20284958 0.20 ENST00000379565.3
ribosomal protein S6 kinase, 90kDa, polypeptide 3
chr17_+_40440481 0.20 ENST00000590726.2
ENST00000452307.2
ENST00000444283.1
ENST00000588868.1
signal transducer and activator of transcription 5A
chr20_-_3140490 0.20 ENST00000449731.1
ENST00000380266.3
U-box domain containing 5
FAST kinase domains 5
chr1_-_26232951 0.20 ENST00000426559.2
ENST00000455785.2
stathmin 1
chr9_-_140082983 0.20 ENST00000323927.2
anaphase promoting complex subunit 2
chr16_+_3062457 0.20 ENST00000445369.2
claudin 9
chr16_-_58034357 0.19 ENST00000562909.1
zinc finger protein 319
chr6_-_136871957 0.19 ENST00000354570.3
microtubule-associated protein 7
chr20_+_21283941 0.19 ENST00000377191.3
ENST00000430571.2
5'-3' exoribonuclease 2
chr19_-_10687983 0.19 ENST00000587069.1
adaptor-related protein complex 1, mu 2 subunit
chr17_+_41132564 0.19 ENST00000361677.1
ENST00000589705.1
RUN domain containing 1
chr2_-_27341765 0.19 ENST00000405600.1
cell growth regulator with EF-hand domain 1
chr1_-_110052302 0.19 ENST00000369864.4
ENST00000369862.1
adhesion molecule with Ig-like domain 1
chr14_-_101034407 0.19 ENST00000443071.2
ENST00000557378.1
brain-enriched guanylate kinase-associated
chr10_-_99258135 0.19 ENST00000327238.10
ENST00000327277.7
ENST00000355839.6
ENST00000437002.1
ENST00000422685.1
MMS19 nucleotide excision repair homolog (S. cerevisiae)
chr5_+_76326187 0.19 ENST00000312916.7
ENST00000506806.1
angiogenic factor with G patch and FHA domains 1
chr1_-_233431458 0.19 ENST00000258229.9
ENST00000430153.1
pecanex-like 2 (Drosophila)
chr2_+_130939235 0.18 ENST00000425361.1
ENST00000457492.1
mitotic spindle organizing protein 2B
chr19_-_46285646 0.18 ENST00000458663.2
dystrophia myotonica-protein kinase
chr19_+_55987998 0.18 ENST00000591164.1
zinc finger protein 628
chr4_-_141348763 0.18 ENST00000509477.1
calmegin
chr4_+_83956237 0.18 ENST00000264389.2
COP9 signalosome subunit 4
chr17_+_42836329 0.18 ENST00000200557.6
ADAM metallopeptidase domain 11
chr1_+_9648921 0.18 ENST00000377376.4
ENST00000340305.5
ENST00000340381.6
transmembrane protein 201
chr1_-_207095324 0.18 ENST00000530505.1
ENST00000367091.3
ENST00000442471.2
Fas apoptotic inhibitory molecule 3
chr19_+_41768401 0.18 ENST00000352456.3
ENST00000595018.1
ENST00000597725.1
heterogeneous nuclear ribonucleoprotein U-like 1
chr17_-_42298201 0.18 ENST00000527034.1
upstream binding transcription factor, RNA polymerase I
chr11_-_417388 0.17 ENST00000332725.3
single immunoglobulin and toll-interleukin 1 receptor (TIR) domain
chr1_+_154947148 0.17 ENST00000368436.1
ENST00000308987.5
CDC28 protein kinase regulatory subunit 1B
chr9_+_140083099 0.17 ENST00000322310.5
Sjogren syndrome nuclear autoantigen 1
chr19_-_40791211 0.17 ENST00000579047.1
v-akt murine thymoma viral oncogene homolog 2
chr14_+_52164820 0.17 ENST00000554167.1
FERM domain containing 6
chr14_-_21905424 0.17 ENST00000553622.1
chromodomain helicase DNA binding protein 8
chr17_-_8151353 0.17 ENST00000315684.8
CTS telomere maintenance complex component 1
chr11_-_417308 0.17 ENST00000397632.3
ENST00000382520.2
single immunoglobulin and toll-interleukin 1 receptor (TIR) domain
chr14_+_56585048 0.17 ENST00000267460.4
pellino E3 ubiquitin protein ligase family member 2
chr17_-_41132010 0.17 ENST00000409103.1
ENST00000360221.4
PTGES3L-AARSD1 readthrough
chr19_-_42721819 0.16 ENST00000336034.4
ENST00000598200.1
ENST00000598727.1
ENST00000596251.1
death effector domain containing 2
chr12_+_110152033 0.16 ENST00000538780.1
family with sequence similarity 222, member A
chr5_+_139027877 0.16 ENST00000302517.3
CXXC finger protein 5
chr19_-_1401486 0.16 ENST00000252288.2
ENST00000447102.3
guanidinoacetate N-methyltransferase
chr6_+_163835669 0.16 ENST00000453779.2
ENST00000275262.7
ENST00000392127.2
ENST00000361752.3
QKI, KH domain containing, RNA binding
chr11_-_78285804 0.15 ENST00000281038.5
ENST00000529571.1
asparaginyl-tRNA synthetase 2, mitochondrial (putative)
chr13_+_35516390 0.15 ENST00000540320.1
ENST00000400445.3
ENST00000310336.4
neurobeachin
chr18_-_45456693 0.15 ENST00000587421.1
SMAD family member 2
chr3_+_47021168 0.15 ENST00000450053.3
ENST00000292309.5
ENST00000383740.2
neurobeachin-like 2
chr16_+_19535133 0.15 ENST00000396212.2
ENST00000381396.5
centriolar coiled coil protein 110kDa
chr2_-_46769694 0.15 ENST00000522587.1
ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E2
chr15_+_40763150 0.15 ENST00000306243.5
ENST00000559991.1
carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 14
chr1_+_6052700 0.15 ENST00000378092.1
ENST00000445501.1
potassium voltage-gated channel, shaker-related subfamily, beta member 2
chrX_-_71933888 0.15 ENST00000373542.4
ENST00000339490.3
ENST00000541944.1
ENST00000373539.3
ENST00000373545.3
phosphorylase kinase, alpha 1 (muscle)
chr8_+_103876528 0.14 ENST00000522939.1
ENST00000524007.1
HCG15011, isoform CRA_a; Protein LOC100996457
chr1_+_110162448 0.14 ENST00000342115.4
ENST00000469039.2
ENST00000474459.1
ENST00000528667.1
adenosine monophosphate deaminase 2
chr17_+_74722912 0.14 ENST00000589977.1
ENST00000591571.1
ENST00000592849.1
ENST00000586738.1
ENST00000588783.1
ENST00000588563.1
ENST00000586752.1
ENST00000588302.1
ENST00000590964.1
ENST00000341249.6
ENST00000588822.1
methyltransferase like 23
chr5_+_156693091 0.14 ENST00000318218.6
ENST00000442283.2
ENST00000522463.1
ENST00000521420.1
cytoplasmic FMR1 interacting protein 2
chr7_-_37488777 0.14 ENST00000445322.1
ENST00000448602.1
engulfment and cell motility 1
chr1_+_156863470 0.14 ENST00000338302.3
ENST00000455314.1
ENST00000292357.7
platelet endothelial aggregation receptor 1
chr5_+_95998714 0.14 ENST00000506811.1
ENST00000514055.1
calpastatin
chr3_-_49066811 0.14 ENST00000442157.1
ENST00000326739.4
IMP (inosine 5'-monophosphate) dehydrogenase 2
chr4_+_86396321 0.14 ENST00000503995.1
Rho GTPase activating protein 24
chr16_-_1823114 0.13 ENST00000177742.3
ENST00000397375.2
mitochondrial ribosomal protein S34
chr18_+_13217965 0.13 ENST00000587905.1
low density lipoprotein receptor class A domain containing 4
chr11_-_65308082 0.13 ENST00000532661.1
latent transforming growth factor beta binding protein 3
chrX_-_153744507 0.13 ENST00000442929.1
ENST00000426266.1
ENST00000359889.5
ENST00000369641.3
ENST00000447601.2
ENST00000434658.2
family with sequence similarity 3, member A
chr16_+_19535235 0.13 ENST00000565376.2
ENST00000396208.2
centriolar coiled coil protein 110kDa
chr7_-_150675372 0.13 ENST00000262186.5
potassium voltage-gated channel, subfamily H (eag-related), member 2
chr14_+_23564700 0.13 ENST00000554203.1
chromosome 14 open reading frame 119
chr1_-_115259337 0.13 ENST00000369535.4
neuroblastoma RAS viral (v-ras) oncogene homolog
chr5_-_1345199 0.13 ENST00000320895.5
CLPTM1-like
chr11_+_826136 0.13 ENST00000528315.1
ENST00000533803.1
EF-hand calcium binding domain 4A
chr17_-_55038375 0.13 ENST00000240316.4
coilin
chr17_-_36831156 0.13 ENST00000325814.5
chromosome 17 open reading frame 96
chr13_-_76111945 0.13 ENST00000355801.4
ENST00000406936.3
COMM domain containing 6

Network of associatons between targets according to the STRING database.

First level regulatory network of HMX1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 0.4 GO:0051885 positive regulation of anagen(GO:0051885)
0.3 0.9 GO:0060929 Purkinje myocyte differentiation(GO:0003168) cardiac pacemaker cell fate commitment(GO:0060927) atrioventricular node cell fate commitment(GO:0060929)
0.2 0.7 GO:0071423 thiosulfate transport(GO:0015709) oxaloacetate transport(GO:0015729) malate transport(GO:0015743) malate transmembrane transport(GO:0071423) oxaloacetate(2-) transmembrane transport(GO:1902356)
0.2 2.8 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.2 0.9 GO:1900154 regulation of bone trabecula formation(GO:1900154) negative regulation of bone trabecula formation(GO:1900155)
0.2 1.0 GO:0051088 PMA-inducible membrane protein ectodomain proteolysis(GO:0051088)
0.2 0.5 GO:1902595 regulation of DNA replication origin binding(GO:1902595)
0.2 0.7 GO:0036228 protein targeting to nuclear inner membrane(GO:0036228)
0.1 0.4 GO:1905000 regulation of membrane repolarization during atrial cardiac muscle cell action potential(GO:1905000)
0.1 1.0 GO:0044333 Wnt signaling pathway involved in digestive tract morphogenesis(GO:0044333)
0.1 0.5 GO:1904116 response to vasopressin(GO:1904116) cellular response to vasopressin(GO:1904117)
0.1 1.0 GO:0021842 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842)
0.1 0.6 GO:1904674 positive regulation of somatic stem cell population maintenance(GO:1904674)
0.1 0.3 GO:0032877 positive regulation of DNA endoreduplication(GO:0032877)
0.1 0.6 GO:0000255 allantoin metabolic process(GO:0000255)
0.1 1.4 GO:0060385 axonogenesis involved in innervation(GO:0060385)
0.1 0.4 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
0.1 0.4 GO:1901675 negative regulation of histone H3-K27 acetylation(GO:1901675)
0.1 0.3 GO:0018076 N-terminal peptidyl-lysine acetylation(GO:0018076) positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948)
0.1 0.8 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.1 0.3 GO:0032053 ciliary basal body organization(GO:0032053)
0.1 0.3 GO:1905098 negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098)
0.1 0.5 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.1 0.7 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.1 0.3 GO:0035544 negative regulation of SNARE complex assembly(GO:0035544)
0.1 0.5 GO:0021592 fourth ventricle development(GO:0021592)
0.1 0.5 GO:2000676 positive regulation of type B pancreatic cell apoptotic process(GO:2000676)
0.1 0.3 GO:0060392 negative regulation of SMAD protein import into nucleus(GO:0060392)
0.1 0.5 GO:0006021 inositol biosynthetic process(GO:0006021)
0.1 0.3 GO:0045079 negative regulation of chemokine biosynthetic process(GO:0045079)
0.1 0.3 GO:0033031 positive regulation of neutrophil apoptotic process(GO:0033031)
0.1 0.4 GO:0008063 Toll signaling pathway(GO:0008063)
0.1 0.2 GO:1902269 positive regulation of polyamine transmembrane transport(GO:1902269)
0.1 0.2 GO:1905166 negative regulation of protein catabolic process in the vacuole(GO:1904351) negative regulation of lysosomal protein catabolic process(GO:1905166)
0.0 0.8 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.0 0.2 GO:0060010 Sertoli cell fate commitment(GO:0060010)
0.0 0.1 GO:1902303 regulation of heart rate by hormone(GO:0003064) negative regulation of potassium ion export(GO:1902303)
0.0 0.2 GO:0006601 creatine biosynthetic process(GO:0006601)
0.0 0.2 GO:0006421 asparaginyl-tRNA aminoacylation(GO:0006421)
0.0 0.1 GO:1903251 multi-ciliated epithelial cell differentiation(GO:1903251)
0.0 0.4 GO:0098881 exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967)
0.0 0.2 GO:0060830 ciliary receptor clustering involved in smoothened signaling pathway(GO:0060830)
0.0 0.4 GO:0003190 atrioventricular valve formation(GO:0003190)
0.0 0.1 GO:0061760 antifungal innate immune response(GO:0061760)
0.0 0.4 GO:0032264 IMP salvage(GO:0032264)
0.0 0.1 GO:0034402 recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex(GO:0034402)
0.0 0.1 GO:0051714 negative regulation of natural killer cell differentiation(GO:0032824) negative regulation of natural killer cell differentiation involved in immune response(GO:0032827) positive regulation of cytolysis in other organism(GO:0051714)
0.0 0.3 GO:0003383 apical constriction(GO:0003383)
0.0 0.6 GO:0016322 neuron remodeling(GO:0016322)
0.0 0.2 GO:1900224 positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry(GO:1900224)
0.0 0.3 GO:0045218 zonula adherens maintenance(GO:0045218)
0.0 0.1 GO:0034476 U1 snRNA 3'-end processing(GO:0034473) U5 snRNA 3'-end processing(GO:0034476)
0.0 0.3 GO:1900246 positive regulation of RIG-I signaling pathway(GO:1900246)
0.0 0.2 GO:0090116 C-5 methylation of cytosine(GO:0090116)
0.0 0.4 GO:0014722 regulation of skeletal muscle contraction by calcium ion signaling(GO:0014722)
0.0 0.1 GO:0045897 positive regulation of transcription during mitosis(GO:0045897)
0.0 0.2 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.0 0.2 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.0 1.1 GO:0034199 activation of protein kinase A activity(GO:0034199)
0.0 0.1 GO:0044029 DNA hypomethylation(GO:0044028) hypomethylation of CpG island(GO:0044029)
0.0 0.2 GO:0097473 cellular response to high light intensity(GO:0071486) retinal rod cell apoptotic process(GO:0097473)
0.0 0.2 GO:0048539 bone marrow development(GO:0048539)
0.0 0.1 GO:0072720 cellular response to mycotoxin(GO:0036146) response to dithiothreitol(GO:0072720)
0.0 0.3 GO:1902659 regulation of glucose mediated signaling pathway(GO:1902659)
0.0 0.4 GO:0051256 mitotic spindle midzone assembly(GO:0051256)
0.0 0.1 GO:1902460 regulation of mesenchymal stem cell proliferation(GO:1902460) positive regulation of mesenchymal stem cell proliferation(GO:1902462)
0.0 0.4 GO:0000338 protein deneddylation(GO:0000338)
0.0 0.5 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.0 0.3 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.0 0.1 GO:0043654 recognition of apoptotic cell(GO:0043654)
0.0 0.1 GO:0006177 GMP biosynthetic process(GO:0006177)
0.0 0.1 GO:0031133 regulation of axon diameter(GO:0031133)
0.0 0.1 GO:0019470 4-hydroxyproline catabolic process(GO:0019470)
0.0 0.4 GO:0080182 histone H3-K4 trimethylation(GO:0080182)
0.0 0.1 GO:1903348 positive regulation of bicellular tight junction assembly(GO:1903348)
0.0 0.0 GO:0035803 egg coat formation(GO:0035803)
0.0 0.4 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.0 0.1 GO:0070995 NADPH oxidation(GO:0070995)
0.0 0.1 GO:2000035 regulation of stem cell division(GO:2000035)
0.0 0.1 GO:0033277 abortive mitotic cell cycle(GO:0033277)
0.0 0.1 GO:0032252 secretory granule localization(GO:0032252)
0.0 0.6 GO:0043555 regulation of translation in response to stress(GO:0043555)
0.0 0.1 GO:0043328 protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328)
0.0 0.1 GO:1903976 negative regulation of glial cell migration(GO:1903976)
0.0 0.1 GO:0001971 negative regulation of activation of membrane attack complex(GO:0001971)
0.0 0.4 GO:0060972 left/right pattern formation(GO:0060972)
0.0 0.1 GO:1902525 regulation of protein monoubiquitination(GO:1902525)
0.0 0.2 GO:0015939 pantothenate metabolic process(GO:0015939)
0.0 0.3 GO:0007097 nuclear migration(GO:0007097)
0.0 0.1 GO:0006049 UDP-N-acetylglucosamine catabolic process(GO:0006049)
0.0 0.1 GO:1904781 positive regulation of protein localization to centrosome(GO:1904781)
0.0 0.3 GO:0003334 keratinocyte development(GO:0003334)
0.0 0.1 GO:0006104 succinyl-CoA metabolic process(GO:0006104)
0.0 0.1 GO:2000270 negative regulation of fibroblast apoptotic process(GO:2000270)
0.0 1.3 GO:0070527 platelet aggregation(GO:0070527)
0.0 0.5 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 0.3 GO:1904152 regulation of retrograde protein transport, ER to cytosol(GO:1904152)
0.0 0.1 GO:0045084 positive regulation of interleukin-12 biosynthetic process(GO:0045084)
0.0 0.2 GO:2000774 positive regulation of cellular senescence(GO:2000774)
0.0 0.1 GO:0098989 NMDA selective glutamate receptor signaling pathway(GO:0098989)
0.0 0.3 GO:0048266 behavioral response to pain(GO:0048266)
0.0 0.3 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.0 0.2 GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.0 0.1 GO:0042695 thelarche(GO:0042695) mammary gland branching involved in thelarche(GO:0060744)
0.0 0.5 GO:0007339 binding of sperm to zona pellucida(GO:0007339)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0044611 nuclear pore inner ring(GO:0044611)
0.2 0.5 GO:1990723 cytoplasmic periphery of the nuclear pore complex(GO:1990723)
0.1 0.4 GO:0031523 Myb complex(GO:0031523)
0.1 0.8 GO:1990393 3M complex(GO:1990393)
0.1 0.4 GO:1990796 photoreceptor cell terminal bouton(GO:1990796)
0.1 0.5 GO:0097513 myosin II filament(GO:0097513)
0.1 0.5 GO:0045323 interleukin-1 receptor complex(GO:0045323)
0.1 0.2 GO:0032279 asymmetric synapse(GO:0032279) symmetric synapse(GO:0032280)
0.0 0.1 GO:0097598 sperm cytoplasmic droplet(GO:0097598)
0.0 0.2 GO:0071817 MMXD complex(GO:0071817)
0.0 0.3 GO:0000125 PCAF complex(GO:0000125)
0.0 1.0 GO:0031233 intrinsic component of external side of plasma membrane(GO:0031233)
0.0 0.2 GO:0031166 integral component of vacuolar membrane(GO:0031166)
0.0 0.1 GO:0097441 basilar dendrite(GO:0097441)
0.0 0.1 GO:1990031 pinceau fiber(GO:1990031)
0.0 0.1 GO:0000814 ESCRT II complex(GO:0000814)
0.0 0.1 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
0.0 0.5 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.4 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.0 0.2 GO:0032444 activin responsive factor complex(GO:0032444)
0.0 1.0 GO:0030673 axolemma(GO:0030673)
0.0 0.5 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.3 GO:0044292 dendrite terminus(GO:0044292)
0.0 0.2 GO:0008274 gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
0.0 0.4 GO:0035102 PRC1 complex(GO:0035102)
0.0 0.6 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.1 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.0 0.1 GO:0097013 phagocytic vesicle lumen(GO:0097013)
0.0 0.1 GO:0030062 mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062)
0.0 0.4 GO:0044295 axonal growth cone(GO:0044295)
0.0 0.3 GO:0005915 zonula adherens(GO:0005915)
0.0 0.3 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.3 GO:0016580 Sin3 complex(GO:0016580)
0.0 0.4 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 1.0 GO:0005871 kinesin complex(GO:0005871)
0.0 0.1 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0015117 thiosulfate transmembrane transporter activity(GO:0015117) oxaloacetate transmembrane transporter activity(GO:0015131)
0.2 2.8 GO:0019826 oxygen sensor activity(GO:0019826)
0.2 0.9 GO:0010736 serum response element binding(GO:0010736)
0.1 0.4 GO:0001160 transcription termination site sequence-specific DNA binding(GO:0001147) transcription termination site DNA binding(GO:0001160)
0.1 1.8 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.1 0.4 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
0.1 0.2 GO:0015459 potassium channel regulator activity(GO:0015459)
0.1 0.9 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.1 0.4 GO:0016509 long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.1 0.2 GO:0001069 regulatory region RNA binding(GO:0001069)
0.1 0.5 GO:0052832 inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate 3-phosphatase activity(GO:0052832) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834)
0.1 0.5 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.0 1.0 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.3 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.0 0.3 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.0 0.3 GO:0001165 RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165)
0.0 0.4 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.5 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.0 0.7 GO:0005522 profilin binding(GO:0005522)
0.0 0.4 GO:0050544 arachidonic acid binding(GO:0050544)
0.0 0.7 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.0 0.2 GO:0042978 ornithine decarboxylase activator activity(GO:0042978)
0.0 0.3 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.8 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
0.0 0.2 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.1 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.0 0.1 GO:0034739 histone deacetylase activity (H4-K16 specific)(GO:0034739)
0.0 0.1 GO:0004657 proline dehydrogenase activity(GO:0004657)
0.0 0.2 GO:1903135 cupric ion binding(GO:1903135)
0.0 0.1 GO:0008745 N-acetylmuramoyl-L-alanine amidase activity(GO:0008745)
0.0 0.6 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 0.5 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 0.2 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.0 0.5 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0 0.1 GO:0004774 succinate-CoA ligase activity(GO:0004774)
0.0 0.1 GO:0070259 tyrosyl-DNA phosphodiesterase activity(GO:0070259)
0.0 1.0 GO:0043236 laminin binding(GO:0043236)
0.0 0.1 GO:0001537 N-acetylgalactosamine 4-O-sulfotransferase activity(GO:0001537)
0.0 0.7 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.2 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.0 0.6 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 0.1 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.0 0.2 GO:0070097 delta-catenin binding(GO:0070097)
0.0 0.4 GO:0048018 receptor agonist activity(GO:0048018)
0.0 0.1 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.1 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.0 0.5 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.1 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0 0.1 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.0 0.4 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 0.3 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.7 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.2 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.0 0.1 GO:0016403 dimethylargininase activity(GO:0016403)
0.0 0.1 GO:0047685 amine sulfotransferase activity(GO:0047685)
0.0 0.5 GO:0044183 protein binding involved in protein folding(GO:0044183)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.8 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 1.0 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 0.5 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 0.6 PID IL5 PATHWAY IL5-mediated signaling events
0.0 0.6 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 0.5 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 0.8 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 0.2 PID S1P S1P3 PATHWAY S1P3 pathway
0.0 0.7 SIG PIP3 SIGNALING IN B LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.8 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 0.9 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.0 0.7 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 1.1 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 0.6 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.0 0.4 REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX Genes involved in Association of licensing factors with the pre-replicative complex
0.0 1.3 REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein
0.0 0.6 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.0 0.9 REACTOME KINESINS Genes involved in Kinesins
0.0 0.2 REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.0 0.3 REACTOME SCFSKP2 MEDIATED DEGRADATION OF P27 P21 Genes involved in SCF(Skp2)-mediated degradation of p27/p21
0.0 0.5 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 1.2 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.3 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 0.7 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 0.6 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.0 0.4 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 0.4 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 0.2 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism