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SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for HNF4A

Z-value: 2.00

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Transcription factors associated with HNF4A

Gene Symbol Gene ID Gene Info
HNF4A
ENSG00000101076.12 hepatocyte nuclear factor 4 alpha

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HNF4Ahg19_v2_chr20_+_43029911_430299410.947.5e-10Click!

Activity profile of HNF4A motif

Sorted Z-values of HNF4A motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr17_+_73606766 18.63 ENST00000578462.1
MYO15B
myosin XVB pseudogene
chr2_-_228244013 11.66 ENST00000304568.3
TM4SF20
transmembrane 4 L six family member 20
chr17_-_36105009 10.98 ENST00000560016.1
ENST00000427275.2
ENST00000561193.1
HNF1B
HNF1 homeobox B
chr3_-_120400960 9.52 ENST00000476082.2
HGD
homogentisate 1,2-dioxygenase
chr3_-_124653579 9.40 ENST00000478191.1
ENST00000311075.3
MUC13
mucin 13, cell surface associated
chr12_+_56075330 8.43 ENST00000394252.3
METTL7B
methyltransferase like 7B
chr7_+_45927956 7.92 ENST00000275525.3
ENST00000457280.1
IGFBP1
insulin-like growth factor binding protein 1
chr16_+_81272287 6.29 ENST00000425577.2
ENST00000564552.1
BCMO1
beta-carotene 15,15'-monooxygenase 1
chr12_+_47617284 6.25 ENST00000549630.1
ENST00000551777.1
PCED1B
PC-esterase domain containing 1B
chr7_+_45928079 6.08 ENST00000468955.1
IGFBP1
insulin-like growth factor binding protein 1
chrX_+_66764375 6.04 ENST00000374690.3
AR
androgen receptor
chr1_+_199996702 6.01 ENST00000367362.3
NR5A2
nuclear receptor subfamily 5, group A, member 2
chr12_+_121416489 5.46 ENST00000541395.1
ENST00000544413.1
HNF1A
HNF1 homeobox A
chr6_-_30080876 5.18 ENST00000376734.3
TRIM31
tripartite motif containing 31
chr6_-_30080863 5.17 ENST00000540829.1
TRIM31
tripartite motif containing 31
chr12_+_121416340 5.10 ENST00000257555.6
ENST00000400024.2
HNF1A
HNF1 homeobox A
chr16_-_16317321 4.95 ENST00000205557.7
ENST00000575728.1
ABCC6
ATP-binding cassette, sub-family C (CFTR/MRP), member 6
chr19_+_39616410 4.79 ENST00000602004.1
ENST00000599470.1
ENST00000321944.4
ENST00000593480.1
ENST00000358301.3
ENST00000593690.1
ENST00000599386.1
PAK4
p21 protein (Cdc42/Rac)-activated kinase 4
chr17_+_4853442 4.77 ENST00000522301.1
ENO3
enolase 3 (beta, muscle)
chr2_+_241544834 4.75 ENST00000319838.5
ENST00000403859.1
ENST00000438013.2
GPR35
G protein-coupled receptor 35
chr17_+_4675175 4.44 ENST00000270560.3
TM4SF5
transmembrane 4 L six family member 5
chr2_+_10442993 4.28 ENST00000423674.1
ENST00000307845.3
HPCAL1
hippocalcin-like 1
chr1_+_199996733 3.99 ENST00000236914.3
NR5A2
nuclear receptor subfamily 5, group A, member 2
chr19_-_36304201 3.91 ENST00000301175.3
PRODH2
proline dehydrogenase (oxidase) 2
chr16_-_57514277 3.80 ENST00000562008.1
ENST00000567214.1
DOK4
docking protein 4
chr22_+_25003626 3.76 ENST00000451366.1
ENST00000406383.2
ENST00000428855.1
GGT1
gamma-glutamyltransferase 1
chr7_-_37956409 3.58 ENST00000436072.2
SFRP4
secreted frizzled-related protein 4
chr19_+_18496957 3.52 ENST00000252809.3
GDF15
growth differentiation factor 15
chr11_-_65381643 3.32 ENST00000309100.3
ENST00000529839.1
ENST00000526293.1
MAP3K11
mitogen-activated protein kinase kinase kinase 11
chr12_+_56114151 3.29 ENST00000547072.1
ENST00000552930.1
ENST00000257895.5
RDH5
retinol dehydrogenase 5 (11-cis/9-cis)
chr5_+_133842243 3.28 ENST00000515627.2
AC005355.2
AC005355.2
chr15_-_63448973 3.24 ENST00000462430.1
RPS27L
ribosomal protein S27-like
chr7_+_192969 3.22 ENST00000313766.5
FAM20C
family with sequence similarity 20, member C
chr7_-_15601595 3.11 ENST00000342526.3
AGMO
alkylglycerol monooxygenase
chr17_-_44896047 3.10 ENST00000225512.5
WNT3
wingless-type MMTV integration site family, member 3
chr4_+_95376396 3.07 ENST00000508216.1
ENST00000514743.1
PDLIM5
PDZ and LIM domain 5
chr17_-_17494972 2.99 ENST00000435340.2
ENST00000255389.5
ENST00000395781.2
PEMT
phosphatidylethanolamine N-methyltransferase
chr12_+_121416437 2.97 ENST00000402929.1
ENST00000535955.1
ENST00000538626.1
ENST00000543427.1
HNF1A
HNF1 homeobox A
chr12_+_121163538 2.96 ENST00000242592.4
ACADS
acyl-CoA dehydrogenase, C-2 to C-3 short chain
chr11_+_119056178 2.95 ENST00000525131.1
ENST00000531114.1
ENST00000355547.5
ENST00000322712.4
PDZD3
PDZ domain containing 3
chr19_-_49339080 2.84 ENST00000595764.1
HSD17B14
hydroxysteroid (17-beta) dehydrogenase 14
chr7_-_47621229 2.80 ENST00000434451.1
TNS3
tensin 3
chr2_+_74648848 2.76 ENST00000409791.1
ENST00000426787.1
ENST00000348227.4
WDR54
WD repeat domain 54
chr12_+_56114189 2.74 ENST00000548082.1
RDH5
retinol dehydrogenase 5 (11-cis/9-cis)
chr22_+_25003606 2.73 ENST00000432867.1
GGT1
gamma-glutamyltransferase 1
chr17_+_4692230 2.73 ENST00000331264.7
GLTPD2
glycolipid transfer protein domain containing 2
chr10_+_96698406 2.61 ENST00000260682.6
CYP2C9
cytochrome P450, family 2, subfamily C, polypeptide 9
chr22_+_25003568 2.59 ENST00000447416.1
GGT1
gamma-glutamyltransferase 1
chr2_-_28113217 2.57 ENST00000444339.2
RBKS
ribokinase
chr2_-_74645669 2.56 ENST00000518401.1
C2orf81
chromosome 2 open reading frame 81
chr17_+_7591747 2.55 ENST00000534050.1
WRAP53
WD repeat containing, antisense to TP53
chr1_-_177939041 2.53 ENST00000308284.6
SEC16B
SEC16 homolog B (S. cerevisiae)
chr17_-_7082861 2.51 ENST00000269299.3
ASGR1
asialoglycoprotein receptor 1
chr5_-_180235755 2.49 ENST00000502678.1
MGAT1
mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
chr12_+_121163602 2.48 ENST00000411593.2
ACADS
acyl-CoA dehydrogenase, C-2 to C-3 short chain
chrX_+_118108571 2.47 ENST00000304778.7
LONRF3
LON peptidase N-terminal domain and ring finger 3
chr14_+_32476072 2.45 ENST00000556949.1
RP11-187E13.2
Uncharacterized protein
chr2_-_74648702 2.36 ENST00000518863.1
C2orf81
chromosome 2 open reading frame 81
chr2_+_28113583 2.34 ENST00000344773.2
ENST00000379624.1
ENST00000342045.2
ENST00000379632.2
ENST00000361704.2
BRE
brain and reproductive organ-expressed (TNFRSF1A modulator)
chr17_+_7591639 2.34 ENST00000396463.2
WRAP53
WD repeat containing, antisense to TP53
chr3_-_53878644 2.28 ENST00000481668.1
ENST00000467802.1
CHDH
choline dehydrogenase
chr19_-_10687983 2.27 ENST00000587069.1
AP1M2
adaptor-related protein complex 1, mu 2 subunit
chr19_+_49055332 2.26 ENST00000201586.2
SULT2B1
sulfotransferase family, cytosolic, 2B, member 1
chr20_+_57875457 2.16 ENST00000337938.2
ENST00000311585.7
ENST00000371028.2
EDN3
endothelin 3
chr19_-_41256207 2.15 ENST00000598485.2
ENST00000470681.1
ENST00000339153.3
ENST00000598729.1
C19orf54
chromosome 19 open reading frame 54
chr11_-_73720122 2.15 ENST00000426995.2
UCP3
uncoupling protein 3 (mitochondrial, proton carrier)
chr2_+_219135115 2.10 ENST00000248451.3
ENST00000273077.4
PNKD
paroxysmal nonkinesigenic dyskinesia
chr11_-_73720276 2.05 ENST00000348534.4
UCP3
uncoupling protein 3 (mitochondrial, proton carrier)
chr20_+_62694461 2.04 ENST00000343484.5
ENST00000395053.3
TCEA2
transcription elongation factor A (SII), 2
chr19_-_48867171 2.03 ENST00000377431.2
ENST00000436660.2
ENST00000541566.1
TMEM143
transmembrane protein 143
chr5_-_79950371 2.02 ENST00000511032.1
ENST00000504396.1
ENST00000505337.1
DHFR
dihydrofolate reductase
chrX_+_118108601 2.01 ENST00000371628.3
LONRF3
LON peptidase N-terminal domain and ring finger 3
chr2_+_73441350 1.90 ENST00000389501.4
SMYD5
SMYD family member 5
chr4_-_120243545 1.89 ENST00000274024.3
FABP2
fatty acid binding protein 2, intestinal
chr13_+_113777105 1.88 ENST00000409306.1
ENST00000375551.3
ENST00000375559.3
F10
coagulation factor X
chr11_-_45939374 1.84 ENST00000533151.1
ENST00000241041.3
PEX16
peroxisomal biogenesis factor 16
chr19_-_10687948 1.82 ENST00000592285.1
AP1M2
adaptor-related protein complex 1, mu 2 subunit
chr16_+_24857552 1.76 ENST00000568579.1
ENST00000567758.1
ENST00000569071.1
ENST00000539472.1
SLC5A11
solute carrier family 5 (sodium/inositol cotransporter), member 11
chr15_-_41120896 1.75 ENST00000299174.5
ENST00000427255.2
PPP1R14D
protein phosphatase 1, regulatory (inhibitor) subunit 14D
chr14_+_23352374 1.75 ENST00000267396.4
ENST00000536884.1
REM2
RAS (RAD and GEM)-like GTP binding 2
chr1_-_15911510 1.73 ENST00000375826.3
AGMAT
agmatine ureohydrolase (agmatinase)
chr17_-_7082668 1.72 ENST00000573083.1
ENST00000574388.1
ASGR1
asialoglycoprotein receptor 1
chr16_+_24857309 1.72 ENST00000565769.1
ENST00000449109.2
ENST00000424767.2
ENST00000545376.1
ENST00000569520.1
SLC5A11
solute carrier family 5 (sodium/inositol cotransporter), member 11
chr2_+_44502630 1.70 ENST00000410056.3
ENST00000409741.1
ENST00000409229.3
SLC3A1
solute carrier family 3 (amino acid transporter heavy chain), member 1
chr19_-_48867291 1.68 ENST00000435956.3
TMEM143
transmembrane protein 143
chr3_-_158390282 1.64 ENST00000264265.3
LXN
latexin
chr1_-_211848899 1.59 ENST00000366998.3
ENST00000540251.1
ENST00000366999.4
NEK2
NIMA-related kinase 2
chr19_-_39303576 1.58 ENST00000594209.1
LGALS4
lectin, galactoside-binding, soluble, 4
chr6_-_86099898 1.53 ENST00000455071.1
RP11-30P6.6
RP11-30P6.6
chr6_-_33385854 1.50 ENST00000488478.1
CUTA
cutA divalent cation tolerance homolog (E. coli)
chr16_+_19429018 1.48 ENST00000542583.2
TMC5
transmembrane channel-like 5
chr11_-_45939565 1.47 ENST00000525192.1
ENST00000378750.5
PEX16
peroxisomal biogenesis factor 16
chr2_+_44502597 1.47 ENST00000260649.6
ENST00000409387.1
SLC3A1
solute carrier family 3 (amino acid transporter heavy chain), member 1
chr13_+_50656307 1.44 ENST00000378180.4
DLEU1
deleted in lymphocytic leukemia 1 (non-protein coding)
chr14_-_51561784 1.42 ENST00000360392.4
TRIM9
tripartite motif containing 9
chr9_+_139839711 1.39 ENST00000224181.3
C8G
complement component 8, gamma polypeptide
chr6_+_43028182 1.37 ENST00000394058.1
KLC4
kinesin light chain 4
chr8_-_98290087 1.35 ENST00000322128.3
TSPYL5
TSPY-like 5
chr16_+_21244986 1.32 ENST00000311620.5
ANKS4B
ankyrin repeat and sterile alpha motif domain containing 4B
chr19_+_39881951 1.32 ENST00000315588.5
ENST00000594368.1
ENST00000599213.2
ENST00000596297.1
MED29
mediator complex subunit 29
chr11_-_118868682 1.30 ENST00000526453.1
RP11-110I1.12
RP11-110I1.12
chr19_-_15235906 1.29 ENST00000600984.1
ILVBL
ilvB (bacterial acetolactate synthase)-like
chr9_+_139839686 1.28 ENST00000371634.2
C8G
complement component 8, gamma polypeptide
chr5_-_16509101 1.27 ENST00000399793.2
FAM134B
family with sequence similarity 134, member B
chr1_+_23695680 1.25 ENST00000454117.1
ENST00000335648.3
ENST00000518821.1
ENST00000437367.2
C1orf213
chromosome 1 open reading frame 213
chr11_+_74870818 1.24 ENST00000525845.1
ENST00000534186.1
ENST00000428359.2
SLCO2B1
solute carrier organic anion transporter family, member 2B1
chr14_-_51562037 1.24 ENST00000338969.5
TRIM9
tripartite motif containing 9
chr2_-_61389168 1.23 ENST00000607743.1
ENST00000605902.1
RP11-493E12.1
RP11-493E12.1
chr6_-_33385655 1.22 ENST00000440279.3
ENST00000607266.1
CUTA
cutA divalent cation tolerance homolog (E. coli)
chr11_-_32456891 1.22 ENST00000452863.3
WT1
Wilms tumor 1
chr1_+_94884023 1.21 ENST00000315713.5
ABCD3
ATP-binding cassette, sub-family D (ALD), member 3
chr1_+_110163202 1.20 ENST00000531203.1
ENST00000256578.3
AMPD2
adenosine monophosphate deaminase 2
chr11_+_64073699 1.19 ENST00000405666.1
ENST00000468670.1
ESRRA
estrogen-related receptor alpha
chrX_+_65382381 1.16 ENST00000519389.1
HEPH
hephaestin
chr6_-_33385823 1.15 ENST00000494751.1
ENST00000374496.3
CUTA
cutA divalent cation tolerance homolog (E. coli)
chr6_+_30130969 1.14 ENST00000376694.4
TRIM15
tripartite motif containing 15
chr7_-_78400598 1.13 ENST00000536571.1
MAGI2
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr8_-_16859690 1.11 ENST00000180166.5
FGF20
fibroblast growth factor 20
chr16_-_88752889 1.11 ENST00000332281.5
SNAI3
snail family zinc finger 3
chr1_+_45274154 1.09 ENST00000450269.1
ENST00000453418.1
ENST00000409335.2
BTBD19
BTB (POZ) domain containing 19
chr11_-_64660916 1.08 ENST00000413053.1
MIR194-2
microRNA 194-2
chr7_+_120628731 1.07 ENST00000310396.5
CPED1
cadherin-like and PC-esterase domain containing 1
chr2_-_62733476 1.07 ENST00000335390.5
TMEM17
transmembrane protein 17
chr4_+_109541722 1.06 ENST00000394667.3
ENST00000502534.1
RPL34
ribosomal protein L34
chr22_-_42526802 1.06 ENST00000359033.4
ENST00000389970.3
ENST00000360608.5
CYP2D6
cytochrome P450, family 2, subfamily D, polypeptide 6
chr19_+_751122 1.03 ENST00000215582.6
MISP
mitotic spindle positioning
chrX_+_135388147 1.02 ENST00000394141.1
GPR112
G protein-coupled receptor 112
chr1_+_241695670 1.02 ENST00000366557.4
KMO
kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
chr15_-_101142401 1.01 ENST00000314742.8
LINS
lines homolog (Drosophila)
chr20_-_44485835 1.00 ENST00000457981.1
ENST00000426915.1
ENST00000217455.4
ACOT8
acyl-CoA thioesterase 8
chr3_+_46919235 0.98 ENST00000449590.1
PTH1R
parathyroid hormone 1 receptor
chr17_-_2614927 0.97 ENST00000435359.1
CLUH
clustered mitochondria (cluA/CLU1) homolog
chr17_-_27503770 0.97 ENST00000533112.1
MYO18A
myosin XVIIIA
chr8_+_22436635 0.95 ENST00000452226.1
ENST00000397760.4
ENST00000339162.7
ENST00000397761.2
PDLIM2
PDZ and LIM domain 2 (mystique)
chr17_-_47786375 0.95 ENST00000511657.1
SLC35B1
solute carrier family 35, member B1
chr2_-_27603582 0.95 ENST00000323703.6
ENST00000436006.1
ZNF513
zinc finger protein 513
chr16_+_2255841 0.94 ENST00000301725.7
MLST8
MTOR associated protein, LST8 homolog (S. cerevisiae)
chr12_-_121973974 0.93 ENST00000538379.1
ENST00000541318.1
ENST00000541511.1
KDM2B
lysine (K)-specific demethylase 2B
chr1_+_113217309 0.93 ENST00000544796.1
ENST00000369644.1
MOV10
Mov10, Moloney leukemia virus 10, homolog (mouse)
chr19_-_14201776 0.92 ENST00000269724.5
SAMD1
sterile alpha motif domain containing 1
chr1_-_167059830 0.88 ENST00000367868.3
GPA33
glycoprotein A33 (transmembrane)
chr2_+_128293323 0.88 ENST00000389524.4
ENST00000428314.1
MYO7B
myosin VIIB
chr12_-_21757774 0.87 ENST00000261195.2
GYS2
glycogen synthase 2 (liver)
chr19_+_41949054 0.86 ENST00000378187.2
C19orf69
chromosome 19 open reading frame 69
chrX_+_65382433 0.86 ENST00000374727.3
HEPH
hephaestin
chr16_+_2255710 0.85 ENST00000397124.1
ENST00000565250.1
MLST8
MTOR associated protein, LST8 homolog (S. cerevisiae)
chr2_-_61389240 0.85 ENST00000606876.1
RP11-493E12.1
RP11-493E12.1
chr10_-_21186144 0.85 ENST00000377119.1
NEBL
nebulette
chr10_+_102106829 0.80 ENST00000370355.2
SCD
stearoyl-CoA desaturase (delta-9-desaturase)
chr17_+_44039704 0.77 ENST00000420682.2
ENST00000415613.2
ENST00000571987.1
ENST00000574436.1
ENST00000431008.3
MAPT
microtubule-associated protein tau
chr1_-_177939348 0.77 ENST00000464631.2
SEC16B
SEC16 homolog B (S. cerevisiae)
chr1_+_241695424 0.77 ENST00000366558.3
ENST00000366559.4
KMO
kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
chr15_-_101142362 0.76 ENST00000559577.1
ENST00000561308.1
ENST00000560133.1
ENST00000560941.1
ENST00000559736.1
ENST00000560272.1
LINS
lines homolog (Drosophila)
chr1_+_113217073 0.75 ENST00000369645.1
MOV10
Mov10, Moloney leukemia virus 10, homolog (mouse)
chr1_-_43855479 0.74 ENST00000290663.6
ENST00000372457.4
MED8
mediator complex subunit 8
chr10_+_18689637 0.73 ENST00000377315.4
CACNB2
calcium channel, voltage-dependent, beta 2 subunit
chr5_+_1801503 0.73 ENST00000274137.5
ENST00000469176.1
NDUFS6
NADH dehydrogenase (ubiquinone) Fe-S protein 6, 13kDa (NADH-coenzyme Q reductase)
chr9_-_35685452 0.73 ENST00000607559.1
TPM2
tropomyosin 2 (beta)
chr1_-_41131326 0.72 ENST00000372684.3
RIMS3
regulating synaptic membrane exocytosis 3
chr16_+_24857162 0.72 ENST00000347898.3
SLC5A11
solute carrier family 5 (sodium/inositol cotransporter), member 11
chr17_+_1646130 0.72 ENST00000453066.1
ENST00000324015.3
ENST00000450523.2
ENST00000453723.1
ENST00000382061.4
SERPINF2
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2
chr20_+_57875758 0.70 ENST00000395654.3
EDN3
endothelin 3
chr20_+_56136136 0.70 ENST00000319441.4
ENST00000543666.1
PCK1
phosphoenolpyruvate carboxykinase 1 (soluble)
chr20_+_57875658 0.70 ENST00000371025.3
EDN3
endothelin 3
chr17_+_41857793 0.68 ENST00000449302.3
C17orf105
chromosome 17 open reading frame 105
chr6_+_131148538 0.63 ENST00000541421.2
SMLR1
small leucine-rich protein 1
chr1_+_113217043 0.61 ENST00000413052.2
MOV10
Mov10, Moloney leukemia virus 10, homolog (mouse)
chr19_-_42758040 0.59 ENST00000593944.1
ERF
Ets2 repressor factor
chr3_+_108541608 0.57 ENST00000426646.1
TRAT1
T cell receptor associated transmembrane adaptor 1
chr19_+_4639514 0.54 ENST00000327473.4
TNFAIP8L1
tumor necrosis factor, alpha-induced protein 8-like 1
chr6_+_30881982 0.54 ENST00000321897.5
ENST00000416670.2
ENST00000542001.1
ENST00000428017.1
VARS2
valyl-tRNA synthetase 2, mitochondrial
chr16_+_66600294 0.53 ENST00000535705.1
ENST00000332695.7
ENST00000336328.6
ENST00000528324.1
ENST00000531885.1
ENST00000529506.1
ENST00000457188.2
ENST00000533666.1
ENST00000533953.1
ENST00000379500.2
ENST00000328020.6
CMTM1
CKLF-like MARVEL transmembrane domain containing 1
chr10_+_70320413 0.53 ENST00000373644.4
TET1
tet methylcytosine dioxygenase 1
chr7_-_75452673 0.53 ENST00000416943.1
CCL24
chemokine (C-C motif) ligand 24
chr1_-_43855444 0.51 ENST00000372455.4
MED8
mediator complex subunit 8
chr14_+_100485712 0.51 ENST00000544450.2
EVL
Enah/Vasp-like
chr16_+_29690358 0.51 ENST00000395384.4
ENST00000562473.1
QPRT
quinolinate phosphoribosyltransferase
chr11_-_71781096 0.51 ENST00000535087.1
ENST00000535838.1
NUMA1
nuclear mitotic apparatus protein 1
chr5_+_136070614 0.50 ENST00000502421.1
CTB-1I21.1
CTB-1I21.1
chr1_+_110163682 0.50 ENST00000358729.4
AMPD2
adenosine monophosphate deaminase 2
chr1_+_110163709 0.50 ENST00000369840.2
ENST00000527846.1
AMPD2
adenosine monophosphate deaminase 2
chr3_+_108541545 0.49 ENST00000295756.6
TRAT1
T cell receptor associated transmembrane adaptor 1
chr3_-_125775629 0.48 ENST00000383598.2
SLC41A3
solute carrier family 41, member 3
chr22_+_30163340 0.48 ENST00000330029.6
ENST00000401406.3
UQCR10
ubiquinol-cytochrome c reductase, complex III subunit X
chr22_+_27068704 0.48 ENST00000444388.1
ENST00000450963.1
ENST00000449017.1
CTA-211A9.5
CTA-211A9.5
chr7_+_33765593 0.46 ENST00000311067.3
RP11-89N17.1
HCG1643653; Uncharacterized protein
chr1_+_48688357 0.44 ENST00000533824.1
ENST00000438567.2
ENST00000236495.5
ENST00000420136.2
SLC5A9
solute carrier family 5 (sodium/sugar cotransporter), member 9
chr5_-_173043591 0.44 ENST00000285908.5
ENST00000480951.1
ENST00000311086.4
BOD1
biorientation of chromosomes in cell division 1
chr1_+_100435535 0.43 ENST00000427993.2
SLC35A3
solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3
chr17_-_28618867 0.43 ENST00000394819.3
ENST00000577623.1
BLMH
bleomycin hydrolase
chr7_-_78400364 0.43 ENST00000535697.1
MAGI2
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr1_+_145727681 0.42 ENST00000417171.1
ENST00000451928.2
PDZK1
PDZ domain containing 1
chr1_-_41131106 0.42 ENST00000372683.1
RIMS3
regulating synaptic membrane exocytosis 3
chr8_-_79717163 0.40 ENST00000520269.1
IL7
interleukin 7
chr20_-_36661826 0.40 ENST00000373448.2
ENST00000373447.3
TTI1
TELO2 interacting protein 1
chr6_+_30882108 0.40 ENST00000541562.1
ENST00000421263.1
VARS2
valyl-tRNA synthetase 2, mitochondrial
chr15_-_100273544 0.39 ENST00000409796.1
ENST00000545021.1
ENST00000344791.2
ENST00000332728.4
ENST00000450512.1
LYSMD4
LysM, putative peptidoglycan-binding, domain containing 4
chr4_+_109541772 0.39 ENST00000506397.1
ENST00000394668.2
RPL34
ribosomal protein L34
chr11_+_118868830 0.37 ENST00000334418.1
CCDC84
coiled-coil domain containing 84
chr17_+_27369918 0.37 ENST00000323372.4
PIPOX
pipecolic acid oxidase

Network of associatons between targets according to the STRING database.

First level regulatory network of HNF4A

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
6.1 24.5 GO:0035565 regulation of pronephros size(GO:0035565)
2.0 6.0 GO:0045720 negative regulation of integrin biosynthetic process(GO:0045720)
1.6 4.9 GO:0032203 telomere formation via telomerase(GO:0032203)
1.6 3.2 GO:0097187 dentinogenesis(GO:0097187)
1.4 10.0 GO:0061113 pancreas morphogenesis(GO:0061113)
1.1 3.3 GO:0032581 ER-dependent peroxisome organization(GO:0032581)
1.1 9.5 GO:0006572 tyrosine catabolic process(GO:0006572)
1.0 3.1 GO:0060061 Spemann organizer formation(GO:0060061)
1.0 3.1 GO:2000118 regulation of sodium-dependent phosphate transport(GO:2000118)
1.0 4.8 GO:0051970 negative regulation of transmission of nerve impulse(GO:0051970)
0.8 9.1 GO:0019344 cysteine biosynthetic process(GO:0019344)
0.7 3.6 GO:0014826 vein smooth muscle contraction(GO:0014826)
0.7 2.1 GO:0061727 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.7 2.7 GO:0035544 negative regulation of SNARE complex assembly(GO:0035544)
0.6 4.2 GO:0015798 myo-inositol transport(GO:0015798)
0.6 1.8 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.6 2.3 GO:0019285 glycine betaine biosynthetic process from choline(GO:0019285) glycine betaine metabolic process(GO:0031455) glycine betaine biosynthetic process(GO:0031456)
0.6 2.3 GO:0000103 sulfate assimilation(GO:0000103)
0.6 3.9 GO:0010133 proline catabolic process to glutamate(GO:0010133)
0.5 2.6 GO:0019303 D-ribose catabolic process(GO:0019303)
0.5 2.0 GO:0046452 dihydrofolate metabolic process(GO:0046452)
0.4 3.2 GO:0015811 L-cystine transport(GO:0015811)
0.4 3.3 GO:0007256 activation of JNKK activity(GO:0007256)
0.3 1.3 GO:1904106 protein localization to microvillus(GO:1904106)
0.3 14.0 GO:0036499 PERK-mediated unfolded protein response(GO:0036499)
0.3 9.4 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.3 1.0 GO:1901253 negative regulation of intracellular transport of viral material(GO:1901253)
0.3 3.1 GO:0046485 ether lipid metabolic process(GO:0046485)
0.3 2.2 GO:0016098 monoterpenoid metabolic process(GO:0016098)
0.3 1.2 GO:0072302 negative regulation of metanephric glomerulus development(GO:0072299) negative regulation of metanephric glomerular mesangial cell proliferation(GO:0072302)
0.3 3.0 GO:0050747 positive regulation of lipoprotein metabolic process(GO:0050747)
0.3 9.2 GO:0046597 negative regulation of viral entry into host cell(GO:0046597)
0.3 2.5 GO:0006049 UDP-N-acetylglucosamine catabolic process(GO:0006049)
0.3 1.9 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
0.3 0.8 GO:1903964 monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.3 3.0 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.2 1.7 GO:0008295 spermidine biosynthetic process(GO:0008295) primary amino compound biosynthetic process(GO:1901162)
0.2 1.0 GO:1903028 positive regulation of opsonization(GO:1903028)
0.2 2.2 GO:0046874 quinolinate metabolic process(GO:0046874)
0.2 2.7 GO:0035279 mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing(GO:0098795)
0.2 1.0 GO:0072334 UDP-galactose transport(GO:0015785) UDP-galactose transmembrane transport(GO:0072334)
0.2 0.7 GO:1904640 response to methionine(GO:1904640)
0.2 1.6 GO:0030997 regulation of centriole-centriole cohesion(GO:0030997)
0.2 4.3 GO:0016559 peroxisome fission(GO:0016559)
0.2 4.2 GO:1990845 adaptive thermogenesis(GO:1990845)
0.2 2.2 GO:0032264 IMP salvage(GO:0032264)
0.2 0.8 GO:0090258 negative regulation of mitochondrial fission(GO:0090258)
0.2 0.9 GO:1904970 brush border assembly(GO:1904970)
0.2 1.6 GO:2000809 positive regulation of synaptic vesicle clustering(GO:2000809)
0.2 0.9 GO:0006438 valyl-tRNA aminoacylation(GO:0006438)
0.2 0.9 GO:0021993 initiation of neural tube closure(GO:0021993)
0.1 3.2 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.1 2.8 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.1 3.7 GO:1901741 positive regulation of myoblast fusion(GO:1901741)
0.1 2.7 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.1 6.0 GO:0042572 retinol metabolic process(GO:0042572)
0.1 1.1 GO:1904338 regulation of dopaminergic neuron differentiation(GO:1904338)
0.1 0.5 GO:2000418 positive regulation of eosinophil migration(GO:2000418)
0.1 0.4 GO:0043418 homocysteine catabolic process(GO:0043418)
0.1 0.7 GO:0010757 negative regulation of plasminogen activation(GO:0010757)
0.1 0.7 GO:0098912 membrane depolarization during atrial cardiac muscle cell action potential(GO:0098912) positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.1 0.4 GO:0010732 protein glutathionylation(GO:0010731) regulation of protein glutathionylation(GO:0010732) negative regulation of protein glutathionylation(GO:0010734)
0.1 4.9 GO:0061718 NADH regeneration(GO:0006735) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.1 1.6 GO:0050965 detection of temperature stimulus involved in sensory perception(GO:0050961) detection of temperature stimulus involved in sensory perception of pain(GO:0050965)
0.1 3.1 GO:0003298 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.1 0.2 GO:0060621 negative regulation of cholesterol import(GO:0060621) negative regulation of sterol import(GO:2000910)
0.1 0.6 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.1 0.7 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.1 1.1 GO:0050862 positive regulation of T cell receptor signaling pathway(GO:0050862)
0.1 2.0 GO:0006825 copper ion transport(GO:0006825)
0.1 0.5 GO:0001826 inner cell mass cell differentiation(GO:0001826)
0.1 0.4 GO:0019477 L-lysine catabolic process to acetyl-CoA(GO:0019474) L-lysine catabolic process(GO:0019477) L-lysine metabolic process(GO:0046440)
0.1 0.9 GO:0032006 regulation of TOR signaling(GO:0032006)
0.0 0.1 GO:1901052 sarcosine metabolic process(GO:1901052) sarcosine catabolic process(GO:1901053)
0.0 0.5 GO:0017062 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.0 3.2 GO:0050690 regulation of defense response to virus by virus(GO:0050690)
0.0 4.2 GO:0018279 protein N-linked glycosylation via asparagine(GO:0018279)
0.0 0.3 GO:0003065 positive regulation of heart rate by epinephrine(GO:0003065)
0.0 1.0 GO:0060732 positive regulation of inositol phosphate biosynthetic process(GO:0060732)
0.0 0.3 GO:0048014 Tie signaling pathway(GO:0048014)
0.0 0.5 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.0 1.8 GO:0032008 positive regulation of TOR signaling(GO:0032008)
0.0 0.3 GO:0031022 nuclear migration along microfilament(GO:0031022)
0.0 3.3 GO:0006635 fatty acid beta-oxidation(GO:0006635)
0.0 4.5 GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436)
0.0 0.7 GO:0070584 mitochondrion morphogenesis(GO:0070584)
0.0 1.3 GO:0071480 cellular response to gamma radiation(GO:0071480)
0.0 1.8 GO:0048286 lung alveolus development(GO:0048286)
0.0 0.1 GO:0070829 response to vitamin B2(GO:0033274) heterochromatin maintenance(GO:0070829)
0.0 1.3 GO:0032784 regulation of DNA-templated transcription, elongation(GO:0032784)
0.0 1.2 GO:1900078 positive regulation of cellular response to insulin stimulus(GO:1900078)
0.0 1.2 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.0 0.9 GO:0019433 triglyceride catabolic process(GO:0019433)
0.0 0.4 GO:0015879 carnitine transport(GO:0015879)
0.0 0.3 GO:0019388 galactose catabolic process(GO:0019388)
0.0 0.2 GO:0023041 neuronal signal transduction(GO:0023041)
0.0 9.3 GO:0032259 methylation(GO:0032259)
0.0 0.3 GO:0061158 3'-UTR-mediated mRNA destabilization(GO:0061158)
0.0 0.0 GO:0009441 glycolate metabolic process(GO:0009441)
0.0 0.0 GO:1904245 regulation of polynucleotide adenylyltransferase activity(GO:1904245) positive regulation of polynucleotide adenylyltransferase activity(GO:1904247)
0.0 0.2 GO:0010990 regulation of SMAD protein complex assembly(GO:0010990) negative regulation of SMAD protein complex assembly(GO:0010991) negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.0 3.9 GO:0010038 response to metal ion(GO:0010038)
0.0 0.2 GO:0034433 steroid esterification(GO:0034433) sterol esterification(GO:0034434) cholesterol esterification(GO:0034435)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 4.8 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.3 2.7 GO:0005579 membrane attack complex(GO:0005579)
0.2 3.1 GO:1990909 Wnt signalosome(GO:1990909)
0.2 20.5 GO:0016459 myosin complex(GO:0016459)
0.1 2.2 GO:0031931 TORC1 complex(GO:0031931)
0.1 1.6 GO:0036057 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.1 4.9 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.1 0.8 GO:0045298 tubulin complex(GO:0045298)
0.1 0.3 GO:0001534 radial spoke(GO:0001534)
0.1 3.3 GO:0005779 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.1 1.5 GO:0005903 brush border(GO:0005903)
0.1 10.2 GO:0005796 Golgi lumen(GO:0005796)
0.1 5.9 GO:0031526 brush border membrane(GO:0031526)
0.1 0.7 GO:0005577 fibrinogen complex(GO:0005577)
0.1 1.1 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.1 1.1 GO:0036038 MKS complex(GO:0036038)
0.0 3.2 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 2.6 GO:0016592 mediator complex(GO:0016592)
0.0 0.7 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 17.4 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 0.5 GO:0045275 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0 8.6 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.0 1.1 GO:0042101 T cell receptor complex(GO:0042101)
0.0 7.6 GO:0005667 transcription factor complex(GO:0005667)
0.0 1.2 GO:0031907 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 1.3 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 1.3 GO:0045171 intercellular bridge(GO:0045171)
0.0 1.2 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 3.0 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 0.4 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0 2.5 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 1.2 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 1.1 GO:0005871 kinesin complex(GO:0005871)
0.0 10.5 GO:0005925 focal adhesion(GO:0005925)
0.0 1.5 GO:0097517 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 3.0 GO:0043296 apical junction complex(GO:0043296)
0.0 2.0 GO:0000777 condensed chromosome kinetochore(GO:0000777)
0.0 1.0 GO:0030173 integral component of Golgi membrane(GO:0030173)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 14.0 GO:0031995 insulin-like growth factor II binding(GO:0031995)
1.0 3.0 GO:0080101 phosphatidyl-N-methylethanolamine N-methyltransferase activity(GO:0000773) phosphatidylethanolamine N-methyltransferase activity(GO:0004608) phosphatidyl-N-dimethylethanolamine N-methyltransferase activity(GO:0080101)
1.0 3.9 GO:0004657 proline dehydrogenase activity(GO:0004657)
0.8 3.3 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.7 3.6 GO:0031708 endothelin B receptor binding(GO:0031708)
0.7 2.1 GO:0004416 hydroxyacylglutathione hydrolase activity(GO:0004416)
0.6 6.0 GO:0005497 androgen binding(GO:0005497)
0.6 4.2 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
0.5 4.8 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.5 4.6 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.5 9.1 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.5 4.2 GO:0004873 asialoglycoprotein receptor activity(GO:0004873)
0.4 2.8 GO:0047045 testosterone 17-beta-dehydrogenase (NADP+) activity(GO:0047045)
0.4 2.0 GO:0033695 oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875)
0.4 3.2 GO:0015184 L-cystine transmembrane transporter activity(GO:0015184)
0.3 3.1 GO:0016714 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
0.3 2.0 GO:0051870 methotrexate binding(GO:0051870)
0.3 2.3 GO:0050294 steroid sulfotransferase activity(GO:0050294)
0.3 4.8 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.3 3.0 GO:0030249 cyclase regulator activity(GO:0010851) guanylate cyclase regulator activity(GO:0030249)
0.3 2.5 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.3 5.0 GO:0043225 anion transmembrane-transporting ATPase activity(GO:0043225)
0.3 1.6 GO:0070699 type II activin receptor binding(GO:0070699)
0.2 1.0 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
0.2 1.2 GO:0044729 hemi-methylated DNA-binding(GO:0044729)
0.2 6.0 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.2 1.0 GO:0005459 UDP-galactose transmembrane transporter activity(GO:0005459)
0.2 9.4 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.2 0.7 GO:0004611 phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613)
0.2 1.6 GO:0016936 galactoside binding(GO:0016936)
0.2 2.2 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.2 5.4 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.2 1.0 GO:0004991 parathyroid hormone receptor activity(GO:0004991)
0.2 0.8 GO:0099609 microtubule lateral binding(GO:0099609)
0.2 7.9 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.2 1.8 GO:0004864 protein phosphatase inhibitor activity(GO:0004864) phosphatase inhibitor activity(GO:0019212)
0.2 2.0 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.2 0.9 GO:0004832 valine-tRNA ligase activity(GO:0004832)
0.2 3.2 GO:0008494 translation activator activity(GO:0008494)
0.1 2.7 GO:0019841 retinol binding(GO:0019841)
0.1 3.6 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 0.5 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.1 0.5 GO:0031728 CCR3 chemokine receptor binding(GO:0031728)
0.1 1.8 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.1 4.9 GO:0070034 telomerase RNA binding(GO:0070034)
0.1 1.7 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.1 0.5 GO:0004514 nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.1 21.0 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.1 1.3 GO:0030976 thiamine pyrophosphate binding(GO:0030976)
0.1 1.1 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.1 0.7 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.1 0.8 GO:0004768 stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
0.1 20.6 GO:0003774 motor activity(GO:0003774)
0.1 4.5 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.1 0.3 GO:0003974 UDP-N-acetylglucosamine 4-epimerase activity(GO:0003974) UDP-glucose 4-epimerase activity(GO:0003978)
0.1 3.1 GO:0005109 frizzled binding(GO:0005109)
0.1 0.9 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
0.1 0.4 GO:0016647 oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.1 0.5 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.1 0.2 GO:0034736 sterol O-acyltransferase activity(GO:0004772) cholesterol O-acyltransferase activity(GO:0034736)
0.1 3.8 GO:0005158 insulin receptor binding(GO:0005158)
0.1 1.6 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.1 0.4 GO:0005124 scavenger receptor binding(GO:0005124)
0.1 2.6 GO:0019200 carbohydrate kinase activity(GO:0019200)
0.1 4.9 GO:0005507 copper ion binding(GO:0005507)
0.0 0.1 GO:0008480 sarcosine dehydrogenase activity(GO:0008480)
0.0 0.9 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.2 GO:0070653 high-density lipoprotein particle receptor binding(GO:0070653)
0.0 1.2 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.0 0.3 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.0 1.8 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.2 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.0 1.1 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.0 1.9 GO:0005504 fatty acid binding(GO:0005504)
0.0 3.2 GO:0030145 manganese ion binding(GO:0030145)
0.0 2.5 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.0 0.8 GO:0031005 filamin binding(GO:0031005)
0.0 9.5 GO:0008168 methyltransferase activity(GO:0008168)
0.0 0.1 GO:0004489 methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489)
0.0 0.1 GO:0004743 pyruvate kinase activity(GO:0004743)
0.0 0.5 GO:0005522 profilin binding(GO:0005522)
0.0 11.7 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.0 0.0 GO:0016623 oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623)
0.0 0.7 GO:0003729 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.0 1.0 GO:0043531 ADP binding(GO:0043531)
0.0 0.7 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 38.9 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.2 6.0 PID CONE PATHWAY Visual signal transduction: Cones
0.1 6.0 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling
0.1 3.1 PID WNT SIGNALING PATHWAY Wnt signaling network
0.1 4.1 PID REELIN PATHWAY Reelin signaling pathway
0.1 4.8 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 3.6 PID ENDOTHELIN PATHWAY Endothelins
0.0 2.0 PID CXCR3 PATHWAY CXCR3-mediated signaling events
0.0 9.9 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 3.6 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 1.9 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 3.6 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.0 1.6 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 2.6 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.0 1.2 PID P73PATHWAY p73 transcription factor network

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 34.7 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.5 14.0 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.3 5.4 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.2 8.4 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.2 9.1 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.2 3.2 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.1 3.6 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.1 1.9 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.1 4.9 REACTOME EXTENSION OF TELOMERES Genes involved in Extension of Telomeres
0.1 3.0 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.1 5.2 REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D Genes involved in Metabolism of steroid hormones and vitamins A and D
0.1 2.0 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.1 2.7 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.1 2.2 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.1 4.8 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.1 4.2 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.1 2.3 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.1 1.7 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.1 1.1 REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1 Genes involved in Signaling by activated point mutants of FGFR1
0.1 0.6 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.1 2.6 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.1 1.7 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.1 1.2 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.0 3.2 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 1.2 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
0.0 0.7 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.0 2.0 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.0 1.6 REACTOME APC CDC20 MEDIATED DEGRADATION OF NEK2A Genes involved in APC-Cdc20 mediated degradation of Nek2A
0.0 1.8 REACTOME CD28 DEPENDENT PI3K AKT SIGNALING Genes involved in CD28 dependent PI3K/Akt signaling
0.0 0.7 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.0 0.9 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 4.1 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 1.4 REACTOME KINESINS Genes involved in Kinesins
0.0 3.1 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 3.5 REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
0.0 0.4 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 6.7 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.0 1.0 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 2.6 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 1.1 REACTOME DOWNSTREAM TCR SIGNALING Genes involved in Downstream TCR signaling
0.0 0.8 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.5 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.0 1.1 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 3.0 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 0.3 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 0.9 REACTOME GLUCOSE METABOLISM Genes involved in Glucose metabolism
0.0 0.3 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling