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SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for HOXA1

Z-value: 1.26

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Transcription factors associated with HOXA1

Gene Symbol Gene ID Gene Info
HOXA1
ENSG00000105991.7 homeobox A1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HOXA1hg19_v2_chr7_-_27135591_27135658-0.811.5e-05Click!

Activity profile of HOXA1 motif

Sorted Z-values of HOXA1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr8_+_40010989 5.97 ENST00000315792.3
C8orf4
chromosome 8 open reading frame 4
chr11_+_114166536 5.96 ENST00000299964.3
NNMT
nicotinamide N-methyltransferase
chr15_-_74501360 5.47 ENST00000323940.5
STRA6
stimulated by retinoic acid 6
chr19_+_16435625 5.06 ENST00000248071.5
ENST00000592003.1
KLF2
Kruppel-like factor 2
chr1_-_153517473 4.82 ENST00000368715.1
S100A4
S100 calcium binding protein A4
chr2_+_8822113 4.70 ENST00000396290.1
ENST00000331129.3
ID2
inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
chr22_+_41968007 4.45 ENST00000460790.1
CSDC2
cold shock domain containing C2, RNA binding
chr15_-_74501310 4.36 ENST00000423167.2
ENST00000432245.2
STRA6
stimulated by retinoic acid 6
chr8_-_27468945 3.99 ENST00000405140.3
CLU
clusterin
chr8_-_27468842 3.63 ENST00000523500.1
CLU
clusterin
chr15_-_64673630 3.60 ENST00000558008.1
ENST00000559519.1
ENST00000380258.2
KIAA0101
KIAA0101
chr8_-_27469196 3.38 ENST00000546343.1
ENST00000560566.1
CLU
clusterin
chr19_-_38746979 3.13 ENST00000591291.1
PPP1R14A
protein phosphatase 1, regulatory (inhibitor) subunit 14A
chr15_-_64673665 3.06 ENST00000300035.4
KIAA0101
KIAA0101
chr12_+_48577366 3.01 ENST00000316554.3
C12orf68
chromosome 12 open reading frame 68
chr8_-_27468717 2.90 ENST00000520796.1
ENST00000520491.1
CLU
clusterin
chr12_+_54402790 2.83 ENST00000040584.4
HOXC8
homeobox C8
chr11_-_104034827 2.81 ENST00000393158.2
PDGFD
platelet derived growth factor D
chr4_-_90229142 2.75 ENST00000609438.1
GPRIN3
GPRIN family member 3
chr8_-_27462822 2.74 ENST00000522098.1
CLU
clusterin
chr5_-_139930713 2.67 ENST00000602657.1
SRA1
steroid receptor RNA activator 1
chr7_+_139528952 2.59 ENST00000416849.2
ENST00000436047.2
ENST00000414508.2
ENST00000448866.1
TBXAS1
thromboxane A synthase 1 (platelet)
chr7_+_74379083 2.56 ENST00000361825.7
GATSL1
GATS protein-like 1
chr2_-_239148599 2.53 ENST00000409182.1
ENST00000409002.3
ENST00000450098.1
ENST00000409356.1
ENST00000409160.3
ENST00000409574.1
ENST00000272937.5
HES6
hes family bHLH transcription factor 6
chr10_+_60272814 2.49 ENST00000373886.3
BICC1
bicaudal C homolog 1 (Drosophila)
chr5_+_133861790 2.45 ENST00000395003.1
PHF15
jade family PHD finger 2
chr11_-_104035088 2.36 ENST00000302251.5
PDGFD
platelet derived growth factor D
chr11_-_126870655 2.30 ENST00000525144.2
KIRREL3
kin of IRRE like 3 (Drosophila)
chr17_+_43239231 2.17 ENST00000591576.1
ENST00000591070.1
ENST00000592695.1
HEXIM2
hexamethylene bis-acetamide inducible 2
chr1_+_45140360 2.08 ENST00000418644.1
ENST00000458657.2
ENST00000441519.1
ENST00000535358.1
ENST00000445071.1
C1orf228
chromosome 1 open reading frame 228
chrX_-_52258669 2.07 ENST00000441417.1
XAGE1A
X antigen family, member 1A
chr3_-_150264272 2.06 ENST00000491660.1
ENST00000487153.1
ENST00000239944.2
SERP1
stress-associated endoplasmic reticulum protein 1
chr16_+_28303804 2.02 ENST00000341901.4
SBK1
SH3 domain binding kinase 1
chr10_+_89264625 1.95 ENST00000371996.4
ENST00000371994.4
MINPP1
multiple inositol-polyphosphate phosphatase 1
chrX_-_10645773 1.94 ENST00000453318.2
MID1
midline 1 (Opitz/BBB syndrome)
chr19_+_7743387 1.85 ENST00000597959.1
CTD-3214H19.16
CTD-3214H19.16
chr11_-_126870683 1.84 ENST00000525704.2
KIRREL3
kin of IRRE like 3 (Drosophila)
chr3_+_14444063 1.80 ENST00000454876.2
ENST00000360861.3
ENST00000416216.2
SLC6A6
solute carrier family 6 (neurotransmitter transporter), member 6
chr5_+_162864575 1.80 ENST00000512163.1
ENST00000393929.1
ENST00000340828.2
ENST00000511683.2
ENST00000510097.1
ENST00000511490.2
ENST00000510664.1
CCNG1
cyclin G1
chr7_+_139529040 1.79 ENST00000455353.1
ENST00000458722.1
ENST00000411653.1
TBXAS1
thromboxane A synthase 1 (platelet)
chr17_+_40932610 1.78 ENST00000246914.5
WNK4
WNK lysine deficient protein kinase 4
chr16_+_28986134 1.74 ENST00000352260.7
SPNS1
spinster homolog 1 (Drosophila)
chr5_-_173173171 1.70 ENST00000517733.1
ENST00000518902.1
CTB-43E15.3
CTB-43E15.3
chr10_+_7745303 1.65 ENST00000429820.1
ENST00000379587.4
ITIH2
inter-alpha-trypsin inhibitor heavy chain 2
chr16_+_28986085 1.64 ENST00000565975.1
ENST00000311008.11
ENST00000323081.8
ENST00000334536.8
SPNS1
spinster homolog 1 (Drosophila)
chr17_-_8027402 1.62 ENST00000541682.2
ENST00000317814.4
ENST00000577735.1
HES7
hes family bHLH transcription factor 7
chr17_-_38821373 1.62 ENST00000394052.3
KRT222
keratin 222
chr7_+_94139105 1.59 ENST00000297273.4
CASD1
CAS1 domain containing 1
chr9_-_116861337 1.58 ENST00000374118.3
KIF12
kinesin family member 12
chr2_+_87808725 1.55 ENST00000413202.1
LINC00152
long intergenic non-protein coding RNA 152
chr7_+_100136811 1.51 ENST00000300176.4
ENST00000262935.4
AGFG2
ArfGAP with FG repeats 2
chr14_+_102196739 1.46 ENST00000556973.1
RP11-796G6.2
Uncharacterized protein
chr16_+_31213206 1.45 ENST00000561916.2
C16orf98
chromosome 16 open reading frame 98
chr15_-_63674218 1.45 ENST00000178638.3
CA12
carbonic anhydrase XII
chr14_-_23822061 1.40 ENST00000397260.3
SLC22A17
solute carrier family 22, member 17
chr7_-_101212244 1.39 ENST00000451953.1
ENST00000434537.1
ENST00000437900.1
LINC01007
long intergenic non-protein coding RNA 1007
chr2_-_190044480 1.37 ENST00000374866.3
COL5A2
collagen, type V, alpha 2
chr8_-_40755333 1.37 ENST00000297737.6
ENST00000315769.7
ZMAT4
zinc finger, matrin-type 4
chr11_+_7626950 1.35 ENST00000530181.1
PPFIBP2
PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr17_-_44896047 1.35 ENST00000225512.5
WNT3
wingless-type MMTV integration site family, member 3
chr8_+_143530791 1.35 ENST00000517894.1
BAI1
brain-specific angiogenesis inhibitor 1
chr19_-_16008880 1.34 ENST00000011989.7
ENST00000221700.6
CYP4F2
cytochrome P450, family 4, subfamily F, polypeptide 2
chr22_-_30642728 1.32 ENST00000403987.3
LIF
leukemia inhibitory factor
chrX_-_1331527 1.31 ENST00000381567.3
ENST00000381566.1
ENST00000400841.2
CRLF2
cytokine receptor-like factor 2
chr10_+_7745232 1.29 ENST00000358415.4
ITIH2
inter-alpha-trypsin inhibitor heavy chain 2
chrX_-_25034065 1.29 ENST00000379044.4
ARX
aristaless related homeobox
chr16_+_30080857 1.28 ENST00000565355.1
ALDOA
aldolase A, fructose-bisphosphate
chr20_+_34742650 1.27 ENST00000373945.1
ENST00000338074.2
EPB41L1
erythrocyte membrane protein band 4.1-like 1
chr17_+_43239191 1.27 ENST00000589230.1
HEXIM2
hexamethylene bis-acetamide inducible 2
chr6_+_151561085 1.26 ENST00000402676.2
AKAP12
A kinase (PRKA) anchor protein 12
chr20_+_36012051 1.26 ENST00000373567.2
SRC
v-src avian sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog
chr10_+_62538248 1.25 ENST00000448257.2
CDK1
cyclin-dependent kinase 1
chrX_-_154493791 1.21 ENST00000369454.3
RAB39B
RAB39B, member RAS oncogene family
chr16_-_28303360 1.21 ENST00000501520.1
RP11-57A19.2
RP11-57A19.2
chr17_+_79495397 1.21 ENST00000417245.2
ENST00000334850.7
FSCN2
fascin homolog 2, actin-bundling protein, retinal (Strongylocentrotus purpuratus)
chr19_+_39916575 1.19 ENST00000601124.1
CTB-60E11.4
CTB-60E11.4
chr20_-_23618582 1.18 ENST00000398411.1
ENST00000376925.3
CST3
cystatin C
chr14_+_24779376 1.14 ENST00000530080.1
LTB4R2
leukotriene B4 receptor 2
chr1_-_92351769 1.10 ENST00000212355.4
TGFBR3
transforming growth factor, beta receptor III
chrX_-_11129229 1.10 ENST00000608176.1
ENST00000433747.2
ENST00000608576.1
ENST00000608916.1
RP11-120D5.1
RP11-120D5.1
chr10_+_62538089 1.10 ENST00000519078.2
ENST00000395284.3
ENST00000316629.4
CDK1
cyclin-dependent kinase 1
chr3_-_149093499 1.09 ENST00000472441.1
TM4SF1
transmembrane 4 L six family member 1
chr3_-_146262488 1.09 ENST00000487389.1
PLSCR1
phospholipid scramblase 1
chr3_-_129375556 1.08 ENST00000510323.1
TMCC1
transmembrane and coiled-coil domain family 1
chr2_-_197226875 1.08 ENST00000409111.1
HECW2
HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2
chr12_+_57998400 1.07 ENST00000548804.1
ENST00000550596.1
ENST00000551835.1
ENST00000549583.1
DTX3
deltex homolog 3 (Drosophila)
chr14_+_96949319 1.06 ENST00000554706.1
AK7
adenylate kinase 7
chr16_+_15596123 1.06 ENST00000452191.2
C16orf45
chromosome 16 open reading frame 45
chr1_-_32384693 1.05 ENST00000602683.1
ENST00000470404.1
PTP4A2
protein tyrosine phosphatase type IVA, member 2
chr2_+_121493717 1.02 ENST00000418323.1
GLI2
GLI family zinc finger 2
chr10_-_75012360 1.01 ENST00000416782.2
ENST00000372945.3
ENST00000372940.3
MRPS16
mitochondrial ribosomal protein S16
chr2_+_87769459 1.00 ENST00000414030.1
ENST00000437561.1
LINC00152
long intergenic non-protein coding RNA 152
chr3_+_112929850 0.99 ENST00000464546.1
BOC
BOC cell adhesion associated, oncogene regulated
chr20_-_36794902 0.97 ENST00000373403.3
TGM2
transglutaminase 2
chr15_-_75134992 0.97 ENST00000568667.1
ULK3
unc-51 like kinase 3
chr19_-_51141196 0.96 ENST00000338916.4
SYT3
synaptotagmin III
chr12_+_64173583 0.94 ENST00000261234.6
TMEM5
transmembrane protein 5
chr12_+_78359999 0.94 ENST00000550503.1
NAV3
neuron navigator 3
chr1_-_40098672 0.94 ENST00000535435.1
HEYL
hes-related family bHLH transcription factor with YRPW motif-like
chr17_+_60447579 0.93 ENST00000450662.2
EFCAB3
EF-hand calcium binding domain 3
chr8_+_86099884 0.92 ENST00000517476.1
ENST00000521429.1
E2F5
E2F transcription factor 5, p130-binding
chr17_-_15502111 0.90 ENST00000354433.3
CDRT1
CMT1A duplicated region transcript 1
chr18_+_3411595 0.87 ENST00000552383.1
TGIF1
TGFB-induced factor homeobox 1
chr1_-_201096312 0.87 ENST00000449188.2
ASCL5
achaete-scute family bHLH transcription factor 5
chr7_-_100808394 0.86 ENST00000445482.2
VGF
VGF nerve growth factor inducible
chr6_+_151561506 0.84 ENST00000253332.1
AKAP12
A kinase (PRKA) anchor protein 12
chr17_-_3499125 0.84 ENST00000399759.3
TRPV1
transient receptor potential cation channel, subfamily V, member 1
chr9_-_112970436 0.84 ENST00000400613.4
C9orf152
chromosome 9 open reading frame 152
chr16_-_55867146 0.83 ENST00000422046.2
CES1
carboxylesterase 1
chr7_-_2354099 0.83 ENST00000222990.3
SNX8
sorting nexin 8
chr3_+_159557637 0.83 ENST00000445224.2
SCHIP1
schwannomin interacting protein 1
chr14_+_24779340 0.81 ENST00000533293.1
ENST00000543919.1
LTB4R2
leukotriene B4 receptor 2
chr15_-_63674034 0.81 ENST00000344366.3
ENST00000422263.2
CA12
carbonic anhydrase XII
chr5_+_133861339 0.80 ENST00000282605.4
ENST00000361895.2
ENST00000402835.1
PHF15
jade family PHD finger 2
chrX_+_48455866 0.80 ENST00000376729.5
ENST00000218056.5
WDR13
WD repeat domain 13
chr8_+_98788003 0.80 ENST00000521545.2
LAPTM4B
lysosomal protein transmembrane 4 beta
chr9_-_123676827 0.80 ENST00000546084.1
TRAF1
TNF receptor-associated factor 1
chr14_+_65453432 0.80 ENST00000246166.2
FNTB
farnesyltransferase, CAAX box, beta
chr19_-_45735138 0.79 ENST00000252482.3
EXOC3L2
exocyst complex component 3-like 2
chr19_-_33360647 0.78 ENST00000590341.1
ENST00000587772.1
ENST00000023064.4
SLC7A9
solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9
chr17_-_39041479 0.76 ENST00000167588.3
KRT20
keratin 20
chr12_-_89919965 0.76 ENST00000548729.1
POC1B-GALNT4
POC1B-GALNT4 readthrough
chr20_+_46130619 0.75 ENST00000372004.3
NCOA3
nuclear receptor coactivator 3
chrX_-_10645724 0.75 ENST00000413894.1
MID1
midline 1 (Opitz/BBB syndrome)
chr11_+_63870660 0.75 ENST00000246841.3
FLRT1
fibronectin leucine rich transmembrane protein 1
chr9_-_130679257 0.75 ENST00000361444.3
ENST00000335791.5
ENST00000343609.2
ST6GALNAC4
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4
chr2_+_74685413 0.74 ENST00000233615.2
WBP1
WW domain binding protein 1
chrX_+_54834791 0.74 ENST00000218439.4
ENST00000375058.1
ENST00000375060.1
MAGED2
melanoma antigen family D, 2
chr4_-_38806404 0.73 ENST00000308979.2
ENST00000505940.1
ENST00000515861.1
TLR1
toll-like receptor 1
chr12_+_123459127 0.72 ENST00000397389.2
ENST00000538755.1
ENST00000536150.1
ENST00000545056.1
ENST00000545612.1
ENST00000538628.1
ENST00000545317.1
OGFOD2
2-oxoglutarate and iron-dependent oxygenase domain containing 2
chr10_-_33623310 0.72 ENST00000395995.1
ENST00000374823.5
ENST00000374821.5
ENST00000374816.3
NRP1
neuropilin 1
chr16_-_21863541 0.72 ENST00000543654.1
NPIPB4
nuclear pore complex interacting protein family, member B4
chr8_+_37887772 0.71 ENST00000338825.4
EIF4EBP1
eukaryotic translation initiation factor 4E binding protein 1
chr8_-_79717750 0.70 ENST00000263851.4
ENST00000379113.2
IL7
interleukin 7
chr17_+_4046964 0.69 ENST00000573984.1
CYB5D2
cytochrome b5 domain containing 2
chrX_+_9431324 0.69 ENST00000407597.2
ENST00000424279.1
ENST00000536365.1
ENST00000441088.1
ENST00000380961.1
ENST00000415293.1
TBL1X
transducin (beta)-like 1X-linked
chr5_-_20575959 0.69 ENST00000507958.1
CDH18
cadherin 18, type 2
chr4_+_113970772 0.68 ENST00000504454.1
ENST00000394537.3
ENST00000357077.4
ENST00000264366.6
ANK2
ankyrin 2, neuronal
chr3_-_9834463 0.68 ENST00000439043.1
TADA3
transcriptional adaptor 3
chr22_-_30866564 0.66 ENST00000435069.1
ENST00000415957.2
ENST00000540910.1
SEC14L3
SEC14-like 3 (S. cerevisiae)
chr10_-_103599591 0.65 ENST00000348850.5
KCNIP2
Kv channel interacting protein 2
chr17_-_57229155 0.65 ENST00000584089.1
SKA2
spindle and kinetochore associated complex subunit 2
chr1_-_24469602 0.65 ENST00000270800.1
IL22RA1
interleukin 22 receptor, alpha 1
chr13_+_36050881 0.63 ENST00000537702.1
NBEA
neurobeachin
chrX_+_70443050 0.63 ENST00000361726.6
GJB1
gap junction protein, beta 1, 32kDa
chr18_+_3412005 0.63 ENST00000401449.1
TGIF1
TGFB-induced factor homeobox 1
chr2_-_175711978 0.62 ENST00000409089.2
CHN1
chimerin 1
chr1_-_45140074 0.62 ENST00000420706.1
ENST00000372235.3
ENST00000372242.3
ENST00000372243.3
ENST00000372244.3
TMEM53
transmembrane protein 53
chr1_+_240255166 0.62 ENST00000319653.9
FMN2
formin 2
chr19_+_5681011 0.61 ENST00000581893.1
ENST00000411793.2
ENST00000301382.4
ENST00000581773.1
ENST00000423665.2
ENST00000583928.1
ENST00000342970.2
ENST00000422535.2
ENST00000581521.1
ENST00000339423.2
HSD11B1L
hydroxysteroid (11-beta) dehydrogenase 1-like
chr12_-_121342170 0.61 ENST00000353487.2
SPPL3
signal peptide peptidase like 3
chr17_-_15501932 0.60 ENST00000583965.1
CDRT1
CMT1A duplicated region transcript 1
chr17_-_40835076 0.60 ENST00000591765.1
CCR10
chemokine (C-C motif) receptor 10
chr20_+_8112824 0.60 ENST00000378641.3
PLCB1
phospholipase C, beta 1 (phosphoinositide-specific)
chr1_-_153513170 0.59 ENST00000368717.2
S100A5
S100 calcium binding protein A5
chr16_-_88752889 0.59 ENST00000332281.5
SNAI3
snail family zinc finger 3
chr17_+_39975544 0.58 ENST00000544340.1
FKBP10
FK506 binding protein 10, 65 kDa
chr7_-_100808843 0.58 ENST00000249330.2
VGF
VGF nerve growth factor inducible
chr9_-_128246769 0.58 ENST00000444226.1
MAPKAP1
mitogen-activated protein kinase associated protein 1
chr1_-_92351666 0.58 ENST00000465892.2
ENST00000417833.2
TGFBR3
transforming growth factor, beta receptor III
chr5_-_180237082 0.56 ENST00000506889.1
MGAT1
mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
chr17_+_39975455 0.56 ENST00000455106.1
FKBP10
FK506 binding protein 10, 65 kDa
chr20_+_60174827 0.55 ENST00000543233.1
CDH4
cadherin 4, type 1, R-cadherin (retinal)
chr21_-_46340884 0.55 ENST00000302347.5
ENST00000517819.1
ITGB2
integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
chr3_+_9834227 0.54 ENST00000287613.7
ENST00000397261.3
ARPC4
actin related protein 2/3 complex, subunit 4, 20kDa
chr12_+_69742121 0.54 ENST00000261267.2
ENST00000549690.1
ENST00000548839.1
LYZ
lysozyme
chr6_-_44233361 0.53 ENST00000275015.5
NFKBIE
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon
chr8_-_66546439 0.52 ENST00000276569.3
ARMC1
armadillo repeat containing 1
chr2_+_74685527 0.52 ENST00000393972.3
ENST00000409737.1
ENST00000428943.1
WBP1
WW domain binding protein 1
chr4_-_144826682 0.52 ENST00000358615.4
ENST00000437468.2
GYPE
glycophorin E (MNS blood group)
chr1_-_103574024 0.52 ENST00000512756.1
ENST00000370096.3
ENST00000358392.2
ENST00000353414.4
COL11A1
collagen, type XI, alpha 1
chr18_+_18943554 0.51 ENST00000580732.2
GREB1L
growth regulation by estrogen in breast cancer-like
chr3_+_111260954 0.50 ENST00000283285.5
CD96
CD96 molecule
chr3_-_179322436 0.50 ENST00000392659.2
ENST00000476781.1
MRPL47
mitochondrial ribosomal protein L47
chr2_-_158345341 0.49 ENST00000435117.1
CYTIP
cytohesin 1 interacting protein
chr2_+_264913 0.49 ENST00000439645.2
ENST00000405233.1
ACP1
acid phosphatase 1, soluble
chr3_-_71774516 0.47 ENST00000425534.3
EIF4E3
eukaryotic translation initiation factor 4E family member 3
chr7_+_77469439 0.47 ENST00000450574.1
ENST00000416283.2
ENST00000248550.7
PHTF2
putative homeodomain transcription factor 2
chr1_-_149812765 0.47 ENST00000369158.1
HIST2H3C
histone cluster 2, H3c
chr1_+_12776118 0.45 ENST00000332530.3
ENST00000359318.5
AADACL3
arylacetamide deacetylase-like 3
chr20_-_30458491 0.45 ENST00000339738.5
DUSP15
dual specificity phosphatase 15
chr13_+_28519343 0.45 ENST00000381026.3
ATP5EP2
ATP synthase, H+ transporting, mitochondrial F1 complex, epsilon subunit pseudogene 2
chr1_+_165864800 0.45 ENST00000469256.2
UCK2
uridine-cytidine kinase 2
chr12_+_21525818 0.45 ENST00000240652.3
ENST00000542023.1
ENST00000537593.1
IAPP
islet amyloid polypeptide
chr3_+_111260856 0.45 ENST00000352690.4
CD96
CD96 molecule
chr10_-_102045882 0.44 ENST00000579542.1
BLOC1S2
biogenesis of lysosomal organelles complex-1, subunit 2
chr2_-_71062938 0.44 ENST00000410009.3
CD207
CD207 molecule, langerin
chr1_-_152539248 0.44 ENST00000368789.1
LCE3E
late cornified envelope 3E
chr10_-_79397547 0.44 ENST00000481070.1
KCNMA1
potassium large conductance calcium-activated channel, subfamily M, alpha member 1
chr2_+_161993465 0.44 ENST00000457476.1
TANK
TRAF family member-associated NFKB activator
chr6_-_15586238 0.43 ENST00000462989.2
DTNBP1
dystrobrevin binding protein 1
chr3_+_196366616 0.43 ENST00000426755.1
PIGX
phosphatidylinositol glycan anchor biosynthesis, class X
chr6_+_99282570 0.43 ENST00000328345.5
POU3F2
POU class 3 homeobox 2
chr7_+_139529085 0.43 ENST00000539806.1
TBXAS1
thromboxane A synthase 1 (platelet)
chr3_-_179322416 0.43 ENST00000259038.2
MRPL47
mitochondrial ribosomal protein L47
chr12_-_10978957 0.43 ENST00000240619.2
TAS2R10
taste receptor, type 2, member 10
chr5_+_150040403 0.43 ENST00000517768.1
ENST00000297130.4
MYOZ3
myozenin 3
chr10_+_90562487 0.42 ENST00000404743.4
LIPM
lipase, family member M
chr9_+_113431059 0.42 ENST00000416899.2
MUSK
muscle, skeletal, receptor tyrosine kinase
chr7_-_3214287 0.42 ENST00000404626.3
AC091801.1
LOC392621; Uncharacterized protein

Network of associatons between targets according to the STRING database.

First level regulatory network of HOXA1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
2.1 16.7 GO:1902847 regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
1.9 5.8 GO:2000437 monocyte extravasation(GO:0035696) regulation of monocyte extravasation(GO:2000437)
1.6 9.8 GO:0061143 alveolar primary septum development(GO:0061143)
1.4 4.1 GO:0002121 inter-male aggressive behavior(GO:0002121)
1.0 5.1 GO:0071409 cellular response to cycloheximide(GO:0071409)
0.9 4.7 GO:0061030 epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030)
0.6 8.5 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.5 1.4 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.5 1.4 GO:0060061 Spemann organizer formation(GO:0060061)
0.4 1.3 GO:0032304 negative regulation of icosanoid secretion(GO:0032304)
0.4 1.3 GO:0002728 negative regulation of natural killer cell cytokine production(GO:0002728)
0.4 1.2 GO:0051541 elastin metabolic process(GO:0051541)
0.4 1.9 GO:0061737 leukotriene signaling pathway(GO:0061737)
0.3 1.0 GO:0021775 smoothened signaling pathway involved in ventral spinal cord interneuron specification(GO:0021775) smoothened signaling pathway involved in spinal cord motor neuron cell fate specification(GO:0021776)
0.3 2.4 GO:0014038 regulation of Schwann cell differentiation(GO:0014038)
0.3 1.7 GO:0007181 transforming growth factor beta receptor complex assembly(GO:0007181)
0.3 1.3 GO:0071393 cellular response to progesterone stimulus(GO:0071393)
0.3 0.9 GO:2000824 negative regulation of androgen receptor activity(GO:2000824)
0.3 6.4 GO:0034356 NAD biosynthesis via nicotinamide riboside salvage pathway(GO:0034356)
0.3 1.1 GO:0000412 histone peptidyl-prolyl isomerization(GO:0000412)
0.3 1.4 GO:0015688 iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
0.3 1.3 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.3 2.3 GO:0055064 chloride ion homeostasis(GO:0055064)
0.2 1.2 GO:0018262 isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine(GO:0018153) isopeptide cross-linking(GO:0018262)
0.2 4.8 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.2 1.5 GO:0072156 distal tubule morphogenesis(GO:0072156)
0.2 0.8 GO:1901594 detection of temperature stimulus involved in thermoception(GO:0050960) response to capsazepine(GO:1901594)
0.2 0.8 GO:0090119 vesicle-mediated cholesterol transport(GO:0090119)
0.2 0.6 GO:0051758 homologous chromosome movement towards spindle pole involved in homologous chromosome segregation(GO:0051758)
0.2 1.6 GO:0014807 regulation of somitogenesis(GO:0014807)
0.2 0.5 GO:1904395 positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395) negative regulation of neuromuscular junction development(GO:1904397)
0.2 2.7 GO:0035372 protein localization to microtubule(GO:0035372)
0.2 3.2 GO:0090520 sphingosine-1-phosphate signaling pathway(GO:0003376) sphingolipid mediated signaling pathway(GO:0090520)
0.1 0.7 GO:1902378 vestibulocochlear nerve structural organization(GO:0021649) positive regulation of cytokine activity(GO:0060301) ganglion morphogenesis(GO:0061552) endothelial tip cell fate specification(GO:0097102) VEGF-activated neuropilin signaling pathway involved in axon guidance(GO:1902378) dorsal root ganglion morphogenesis(GO:1904835) otic placode development(GO:1905040)
0.1 0.7 GO:0036371 protein localization to T-tubule(GO:0036371)
0.1 0.5 GO:0043376 regulation of CD8-positive, alpha-beta T cell differentiation(GO:0043376)
0.1 0.8 GO:0018343 protein farnesylation(GO:0018343)
0.1 1.1 GO:1903976 negative regulation of glial cell migration(GO:1903976)
0.1 0.4 GO:0042137 sequestering of neurotransmitter(GO:0042137)
0.1 0.4 GO:0015680 intracellular copper ion transport(GO:0015680)
0.1 1.0 GO:0021831 embryonic olfactory bulb interneuron precursor migration(GO:0021831)
0.1 0.5 GO:0009224 CMP salvage(GO:0006238) CMP biosynthetic process(GO:0009224) CMP metabolic process(GO:0046035)
0.1 1.1 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659) regulation of DNA topoisomerase (ATP-hydrolyzing) activity(GO:2000371) positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity(GO:2000373)
0.1 0.8 GO:0035624 receptor transactivation(GO:0035624)
0.1 0.2 GO:0030185 nitric oxide transport(GO:0030185)
0.1 0.3 GO:0034130 toll-like receptor 1 signaling pathway(GO:0034130)
0.1 0.9 GO:1990928 response to amino acid starvation(GO:1990928)
0.1 0.8 GO:0018344 protein geranylgeranylation(GO:0018344)
0.1 0.7 GO:0045163 clustering of voltage-gated potassium channels(GO:0045163)
0.1 0.4 GO:0001808 negative regulation of type IV hypersensitivity(GO:0001808)
0.1 2.1 GO:0060124 positive regulation of growth hormone secretion(GO:0060124)
0.1 1.3 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.1 0.3 GO:0060370 susceptibility to T cell mediated cytotoxicity(GO:0060370)
0.1 0.5 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.1 0.6 GO:0030950 establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.1 0.4 GO:1904844 response to L-glutamine(GO:1904844) cellular response to L-glutamine(GO:1904845)
0.1 0.7 GO:0070294 renal sodium ion absorption(GO:0070294)
0.1 0.6 GO:0045586 regulation of gamma-delta T cell differentiation(GO:0045586)
0.1 0.7 GO:0090043 regulation of tubulin deacetylation(GO:0090043)
0.1 0.1 GO:0010512 negative regulation of phosphatidylinositol biosynthetic process(GO:0010512)
0.1 0.5 GO:0035989 tendon development(GO:0035989)
0.1 0.2 GO:0050894 determination of affect(GO:0050894)
0.1 0.6 GO:0051533 positive regulation of NFAT protein import into nucleus(GO:0051533)
0.1 0.3 GO:1990022 RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022)
0.1 0.6 GO:0006049 UDP-N-acetylglucosamine catabolic process(GO:0006049)
0.1 0.9 GO:0060155 platelet dense granule organization(GO:0060155)
0.1 0.8 GO:0051601 exocyst localization(GO:0051601)
0.1 1.0 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.1 0.8 GO:0061469 regulation of type B pancreatic cell proliferation(GO:0061469)
0.1 0.4 GO:0006499 N-terminal protein myristoylation(GO:0006499)
0.1 0.2 GO:0031508 pericentric heterochromatin assembly(GO:0031508) regulation of chromosome condensation(GO:0060623)
0.0 0.5 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
0.0 0.3 GO:0051697 protein delipidation(GO:0051697)
0.0 0.3 GO:0050803 regulation of synapse structure or activity(GO:0050803)
0.0 1.4 GO:0002021 response to dietary excess(GO:0002021)
0.0 0.8 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.0 0.3 GO:0002933 lipid hydroxylation(GO:0002933)
0.0 2.9 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.0 0.5 GO:0042940 D-amino acid transport(GO:0042940)
0.0 0.2 GO:0050917 sensory perception of umami taste(GO:0050917)
0.0 0.1 GO:0045554 TRAIL biosynthetic process(GO:0045553) regulation of TRAIL biosynthetic process(GO:0045554) positive regulation of TRAIL biosynthetic process(GO:0045556)
0.0 0.4 GO:0021979 hypothalamus cell differentiation(GO:0021979)
0.0 0.2 GO:0018101 protein citrullination(GO:0018101) histone citrullination(GO:0036414)
0.0 0.2 GO:1903644 regulation of chaperone-mediated protein folding(GO:1903644)
0.0 0.3 GO:0098912 membrane depolarization during atrial cardiac muscle cell action potential(GO:0098912) positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.0 0.4 GO:0055059 asymmetric neuroblast division(GO:0055059)
0.0 0.6 GO:0015868 purine ribonucleotide transport(GO:0015868)
0.0 0.1 GO:0060005 vestibular reflex(GO:0060005)
0.0 1.0 GO:0045663 positive regulation of myoblast differentiation(GO:0045663)
0.0 0.3 GO:0002857 positive regulation of natural killer cell mediated immune response to tumor cell(GO:0002857) positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002860)
0.0 0.4 GO:0045078 positive regulation of interferon-gamma biosynthetic process(GO:0045078)
0.0 0.2 GO:1902952 positive regulation of dendritic spine maintenance(GO:1902952)
0.0 0.8 GO:0045109 intermediate filament organization(GO:0045109)
0.0 2.0 GO:2000273 positive regulation of receptor activity(GO:2000273)
0.0 0.3 GO:0051612 negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.0 0.7 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0 1.0 GO:0045880 positive regulation of smoothened signaling pathway(GO:0045880)
0.0 1.0 GO:0008045 motor neuron axon guidance(GO:0008045)
0.0 0.1 GO:1904647 response to rotenone(GO:1904647)
0.0 0.5 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)
0.0 1.3 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.0 0.4 GO:0006451 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.0 2.2 GO:0035690 cellular response to drug(GO:0035690)
0.0 2.3 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.0 0.4 GO:1903874 ferrous iron transport(GO:0015684) ferrous iron transmembrane transport(GO:1903874)
0.0 0.1 GO:0071163 DNA replication preinitiation complex assembly(GO:0071163)
0.0 0.4 GO:0015671 oxygen transport(GO:0015671)
0.0 1.0 GO:0097503 sialylation(GO:0097503)
0.0 0.9 GO:0042462 eye photoreceptor cell development(GO:0042462)
0.0 0.8 GO:0048873 homeostasis of number of cells within a tissue(GO:0048873)
0.0 0.3 GO:0003356 regulation of cilium beat frequency(GO:0003356)
0.0 0.9 GO:1903861 positive regulation of dendrite extension(GO:1903861)
0.0 0.2 GO:0072498 embryonic skeletal joint development(GO:0072498)
0.0 0.9 GO:0072348 sulfur compound transport(GO:0072348)
0.0 0.1 GO:1903597 negative regulation of gap junction assembly(GO:1903597)
0.0 0.4 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.0 1.1 GO:0015949 nucleobase-containing small molecule interconversion(GO:0015949)
0.0 1.9 GO:0070125 mitochondrial translational elongation(GO:0070125)
0.0 2.0 GO:0043647 inositol phosphate metabolic process(GO:0043647)
0.0 4.3 GO:0043488 regulation of mRNA stability(GO:0043488)
0.0 0.4 GO:0002479 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent(GO:0002479)
0.0 0.1 GO:0090116 C-5 methylation of cytosine(GO:0090116)
0.0 2.1 GO:0018107 peptidyl-threonine phosphorylation(GO:0018107)
0.0 2.1 GO:0007368 determination of left/right symmetry(GO:0007368)
0.0 0.8 GO:0010803 regulation of tumor necrosis factor-mediated signaling pathway(GO:0010803)
0.0 0.2 GO:0098915 membrane repolarization during ventricular cardiac muscle cell action potential(GO:0098915)
0.0 0.3 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.0 0.4 GO:0021904 dorsal/ventral neural tube patterning(GO:0021904)
0.0 0.1 GO:0010727 negative regulation of hydrogen peroxide metabolic process(GO:0010727)
0.0 4.0 GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043123)
0.0 2.1 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0 0.6 GO:0007019 microtubule depolymerization(GO:0007019)
0.0 0.4 GO:0010107 potassium ion import(GO:0010107)
0.0 0.0 GO:0051852 disruption by host of symbiont cells(GO:0051852) killing by host of symbiont cells(GO:0051873)
0.0 0.7 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.0 0.1 GO:1904220 regulation of serine C-palmitoyltransferase activity(GO:1904220)
0.0 0.7 GO:0050829 defense response to Gram-negative bacterium(GO:0050829)
0.0 0.1 GO:0048845 venous blood vessel morphogenesis(GO:0048845)
0.0 2.3 GO:0009952 anterior/posterior pattern specification(GO:0009952)
0.0 0.5 GO:0015986 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 16.7 GO:0034366 spherical high-density lipoprotein particle(GO:0034366)
0.5 2.4 GO:0097125 cyclin B1-CDK1 complex(GO:0097125)
0.5 1.4 GO:0005588 collagen type V trimer(GO:0005588)
0.3 1.7 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.2 0.8 GO:0005965 protein farnesyltransferase complex(GO:0005965)
0.1 0.6 GO:0071458 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458)
0.1 1.4 GO:1990909 Wnt signalosome(GO:1990909)
0.1 0.3 GO:0035354 Toll-like receptor 1-Toll-like receptor 2 protein complex(GO:0035354)
0.1 0.5 GO:0034688 integrin alphaM-beta2 complex(GO:0034688)
0.1 0.2 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.1 0.7 GO:0097443 sorting endosome(GO:0097443)
0.1 0.5 GO:0000275 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275)
0.1 0.2 GO:0045160 myosin I complex(GO:0045160)
0.0 4.4 GO:0043198 dendritic shaft(GO:0043198)
0.0 0.5 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 0.8 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 0.7 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 3.9 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 0.7 GO:0042383 sarcolemma(GO:0042383)
0.0 0.3 GO:0035253 ciliary rootlet(GO:0035253)
0.0 2.7 GO:0045171 intercellular bridge(GO:0045171)
0.0 0.7 GO:0030914 STAGA complex(GO:0030914)
0.0 0.4 GO:0060199 clathrin-sculpted glutamate transport vesicle(GO:0060199) clathrin-sculpted glutamate transport vesicle membrane(GO:0060203)
0.0 2.0 GO:0097542 ciliary tip(GO:0097542)
0.0 1.8 GO:0070160 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.0 1.0 GO:0044295 axonal growth cone(GO:0044295)
0.0 1.0 GO:0005763 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 1.9 GO:0031430 M band(GO:0031430)
0.0 0.9 GO:0031083 BLOC-1 complex(GO:0031083)
0.0 13.9 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 0.7 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 0.2 GO:0001740 Barr body(GO:0001740)
0.0 0.7 GO:0031932 TORC2 complex(GO:0031932)
0.0 0.8 GO:0030904 retromer complex(GO:0030904)
0.0 0.2 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.0 1.7 GO:0005871 kinesin complex(GO:0005871)
0.0 1.4 GO:0032420 stereocilium(GO:0032420)
0.0 0.9 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 0.4 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 1.6 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.2 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.0 0.5 GO:0034518 mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518)
0.0 0.5 GO:0005922 connexon complex(GO:0005922)
0.0 0.2 GO:0005787 signal peptidase complex(GO:0005787)
0.0 0.3 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 0.4 GO:0001931 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0 0.7 GO:0005876 spindle microtubule(GO:0005876)
0.0 0.2 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.9 GO:0005762 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 0.8 GO:0031594 neuromuscular junction(GO:0031594)
0.0 4.2 GO:0000790 nuclear chromatin(GO:0000790)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 6.0 GO:0008112 nicotinamide N-methyltransferase activity(GO:0008112) pyridine N-methyltransferase activity(GO:0030760)
1.2 4.8 GO:0004796 thromboxane-A synthase activity(GO:0004796) 12-hydroxyheptadecatrienoic acid synthase activity(GO:0036134)
0.7 2.0 GO:0008969 phosphohistidine phosphatase activity(GO:0008969)
0.6 1.7 GO:0070123 transforming growth factor beta receptor activity, type III(GO:0070123)
0.5 3.2 GO:0046624 sphingolipid transporter activity(GO:0046624)
0.5 16.7 GO:0051787 misfolded protein binding(GO:0051787)
0.5 1.9 GO:0001632 leukotriene B4 receptor activity(GO:0001632)
0.4 1.3 GO:0097258 tocopherol omega-hydroxylase activity(GO:0052870) alpha-tocopherol omega-hydroxylase activity(GO:0052871) 20-hydroxy-leukotriene B4 omega oxidase activity(GO:0097258) 20-aldehyde-leukotriene B4 20-monooxygenase activity(GO:0097259)
0.4 1.3 GO:0005146 leukemia inhibitory factor receptor binding(GO:0005146)
0.3 3.4 GO:0097322 7SK snRNA binding(GO:0097322)
0.3 1.0 GO:0004727 prenylated protein tyrosine phosphatase activity(GO:0004727)
0.2 0.9 GO:0035939 microsatellite binding(GO:0035939)
0.2 1.6 GO:0016413 O-acetyltransferase activity(GO:0016413)
0.2 4.8 GO:0050786 RAGE receptor binding(GO:0050786)
0.2 0.8 GO:0004660 protein farnesyltransferase activity(GO:0004660)
0.2 9.5 GO:0051183 vitamin transporter activity(GO:0051183)
0.2 5.8 GO:0005112 Notch binding(GO:0005112)
0.2 1.2 GO:0038085 vascular endothelial growth factor binding(GO:0038085)
0.2 0.8 GO:0047374 methylumbelliferyl-acetate deacetylase activity(GO:0047374)
0.2 1.1 GO:0004127 cytidylate kinase activity(GO:0004127)
0.1 5.3 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.1 1.8 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.1 2.3 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.1 0.7 GO:0042015 interleukin-20 binding(GO:0042015)
0.1 1.3 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.1 2.1 GO:0008179 adenylate cyclase binding(GO:0008179)
0.1 0.8 GO:0097603 temperature-gated ion channel activity(GO:0097603)
0.1 2.4 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.1 0.6 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.1 1.2 GO:0071253 connexin binding(GO:0071253)
0.1 0.4 GO:0032767 copper-dependent protein binding(GO:0032767)
0.1 0.4 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.1 0.8 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.1 0.4 GO:0004514 nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.1 0.7 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250) ER retention sequence binding(GO:0046923)
0.1 1.3 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.1 0.4 GO:0051373 FATZ binding(GO:0051373)
0.1 0.2 GO:0031877 somatostatin receptor binding(GO:0031877)
0.1 0.6 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.1 0.9 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.1 0.2 GO:0010698 acetyltransferase activator activity(GO:0010698)
0.1 1.4 GO:0048018 receptor agonist activity(GO:0048018)
0.1 0.3 GO:0035663 Toll-like receptor 2 binding(GO:0035663)
0.1 1.5 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.1 0.5 GO:0030369 ICAM-3 receptor activity(GO:0030369)
0.1 0.4 GO:0035368 selenocysteine insertion sequence binding(GO:0035368)
0.1 0.4 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.1 1.0 GO:0008527 taste receptor activity(GO:0008527)
0.1 0.5 GO:0004849 uridine kinase activity(GO:0004849)
0.0 1.4 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.8 GO:0031996 thioesterase binding(GO:0031996)
0.0 1.1 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 0.3 GO:0001602 pancreatic polypeptide receptor activity(GO:0001602)
0.0 0.7 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 0.5 GO:0003796 lysozyme activity(GO:0003796)
0.0 0.3 GO:0047288 monosialoganglioside sialyltransferase activity(GO:0047288)
0.0 0.7 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.0 1.5 GO:0070410 co-SMAD binding(GO:0070410)
0.0 0.2 GO:0030492 hemoglobin binding(GO:0030492)
0.0 0.3 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 0.6 GO:0005243 gap junction channel activity(GO:0005243)
0.0 0.2 GO:0017098 sulfonylurea receptor binding(GO:0017098)
0.0 0.1 GO:0051800 phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity(GO:0051800)
0.0 1.4 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.0 2.7 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 0.2 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.0 1.8 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.3 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.0 0.2 GO:0050509 N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity(GO:0050509)
0.0 0.7 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 4.2 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 0.4 GO:0015093 ferrous iron transmembrane transporter activity(GO:0015093)
0.0 0.4 GO:0005344 oxygen transporter activity(GO:0005344)
0.0 1.9 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 0.8 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.2 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.0 0.1 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.4 GO:0005537 mannose binding(GO:0005537)
0.0 0.6 GO:0005234 extracellular-glutamate-gated ion channel activity(GO:0005234)
0.0 0.1 GO:0004423 iduronate-2-sulfatase activity(GO:0004423)
0.0 0.9 GO:1901682 sulfur compound transmembrane transporter activity(GO:1901682)
0.0 2.9 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.4 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.0 0.1 GO:1990189 peptide-serine-N-acetyltransferase activity(GO:1990189)
0.0 0.6 GO:0031418 L-ascorbic acid binding(GO:0031418)
0.0 0.4 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 2.6 GO:0051219 phosphoprotein binding(GO:0051219)
0.0 0.6 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 1.5 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 0.1 GO:0008048 calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.0 0.5 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 1.2 GO:0005507 copper ion binding(GO:0005507)
0.0 0.1 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0 0.6 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.8 GO:0050699 WW domain binding(GO:0050699)
0.0 0.1 GO:0048406 nerve growth factor binding(GO:0048406)
0.0 0.3 GO:0070330 aromatase activity(GO:0070330)
0.0 0.1 GO:0008240 tripeptidyl-peptidase activity(GO:0008240)
0.0 0.5 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 0.3 GO:0001608 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.1 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.0 0.1 GO:0022833 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.0 0.2 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 0.1 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.4 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.1 19.4 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.1 7.1 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 0.8 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 1.4 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.7 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 1.2 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 1.0 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 2.5 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 0.8 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 1.5 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 3.1 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 1.9 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.0 2.7 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 2.0 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.0 0.4 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 0.7 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.0 0.6 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.0 1.8 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 0.5 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.0 0.5 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 0.8 PID HIV NEF PATHWAY HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.0 0.6 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 2.0 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 6.0 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 0.2 SIG CHEMOTAXIS Genes related to chemotaxis
0.0 1.3 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 0.6 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 1.1 PID RAC1 PATHWAY RAC1 signaling pathway
0.0 3.3 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.7 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 0.1 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.4 REACTOME RAF MAP KINASE CASCADE Genes involved in RAF/MAP kinase cascade
0.1 2.3 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.1 4.1 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.1 1.9 REACTOME EICOSANOID LIGAND BINDING RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
0.1 17.3 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.1 5.4 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.1 1.3 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.1 0.8 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.1 0.7 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.6 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 5.9 REACTOME PHASE II CONJUGATION Genes involved in Phase II conjugation
0.0 2.5 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0 0.7 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 7.0 REACTOME SIGNALING BY PDGF Genes involved in Signaling by PDGF
0.0 1.4 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 2.8 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 0.5 REACTOME DEFENSINS Genes involved in Defensins
0.0 2.1 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 2.1 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 1.2 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.5 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 0.5 REACTOME ACTIVATION OF NF KAPPAB IN B CELLS Genes involved in Activation of NF-kappaB in B Cells
0.0 0.8 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 1.3 REACTOME TRAFFICKING OF AMPA RECEPTORS Genes involved in Trafficking of AMPA receptors
0.0 0.4 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 1.0 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.3 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.7 REACTOME EXTRACELLULAR MATRIX ORGANIZATION Genes involved in Extracellular matrix organization
0.0 0.4 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.0 0.9 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription