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SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for HOXA10_HOXB9

Z-value: 0.37

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Transcription factors associated with HOXA10_HOXB9

Gene Symbol Gene ID Gene Info
HOXA10
ENSG00000253293.3 homeobox A10
HOXB9
ENSG00000170689.8 homeobox B9

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HOXB9hg19_v2_chr17_-_46703826_46703845-0.742.1e-04Click!
HOXA10hg19_v2_chr7_-_27213893_27213954-0.697.4e-04Click!

Activity profile of HOXA10_HOXB9 motif

Sorted Z-values of HOXA10_HOXB9 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr7_-_41742697 1.52 ENST00000242208.4
INHBA
inhibin, beta A
chrX_+_105936982 1.19 ENST00000418562.1
RNF128
ring finger protein 128, E3 ubiquitin protein ligase
chr1_+_153003671 1.15 ENST00000307098.4
SPRR1B
small proline-rich protein 1B
chrX_+_105937068 1.05 ENST00000324342.3
RNF128
ring finger protein 128, E3 ubiquitin protein ligase
chr4_+_71384300 0.98 ENST00000504451.1
AMTN
amelotin
chr4_+_71384257 0.91 ENST00000339336.4
AMTN
amelotin
chr19_-_53636125 0.77 ENST00000601493.1
ENST00000599261.1
ENST00000597503.1
ENST00000500065.4
ENST00000243643.4
ENST00000594011.1
ENST00000455735.2
ENST00000595193.1
ENST00000448501.1
ENST00000421033.1
ENST00000440291.1
ENST00000595813.1
ENST00000600574.1
ENST00000596051.1
ENST00000601110.1
ZNF415
zinc finger protein 415
chrX_-_73072534 0.77 ENST00000429829.1
XIST
X inactive specific transcript (non-protein coding)
chr3_-_172241250 0.75 ENST00000420541.2
ENST00000241261.2
TNFSF10
tumor necrosis factor (ligand) superfamily, member 10
chr2_+_113885138 0.70 ENST00000409930.3
IL1RN
interleukin 1 receptor antagonist
chr11_+_113185778 0.67 ENST00000524580.2
TTC12
tetratricopeptide repeat domain 12
chr4_-_119274121 0.66 ENST00000296498.3
PRSS12
protease, serine, 12 (neurotrypsin, motopsin)
chr15_-_83952071 0.66 ENST00000569704.1
BNC1
basonuclin 1
chr1_+_160370344 0.64 ENST00000368061.2
VANGL2
VANGL planar cell polarity protein 2
chr5_+_166711804 0.62 ENST00000518659.1
ENST00000545108.1
TENM2
teneurin transmembrane protein 2
chr22_-_31324215 0.61 ENST00000429468.1
MORC2
MORC family CW-type zinc finger 2
chr3_+_189507460 0.57 ENST00000434928.1
TP63
tumor protein p63
chr3_-_18480260 0.57 ENST00000454909.2
SATB1
SATB homeobox 1
chr11_-_104905840 0.57 ENST00000526568.1
ENST00000393136.4
ENST00000531166.1
ENST00000534497.1
ENST00000527979.1
ENST00000446369.1
ENST00000353247.5
ENST00000528974.1
ENST00000533400.1
ENST00000525825.1
ENST00000436863.3
CASP1
caspase 1, apoptosis-related cysteine peptidase
chr3_+_189507523 0.56 ENST00000437221.1
ENST00000392463.2
ENST00000392461.3
ENST00000449992.1
ENST00000456148.1
TP63
tumor protein p63
chr17_+_61151306 0.56 ENST00000580068.1
ENST00000580466.1
TANC2
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
chr21_-_28215332 0.55 ENST00000517777.1
ADAMTS1
ADAM metallopeptidase with thrombospondin type 1 motif, 1
chr11_-_104972158 0.55 ENST00000598974.1
ENST00000593315.1
ENST00000594519.1
ENST00000415981.2
ENST00000525374.1
ENST00000375707.1
CASP1
CARD16
CARD17
caspase 1, apoptosis-related cysteine peptidase
caspase recruitment domain family, member 16
caspase recruitment domain family, member 17
chr11_-_104916034 0.53 ENST00000528513.1
ENST00000375706.2
ENST00000375704.3
CARD16
caspase recruitment domain family, member 16
chr1_+_117963209 0.51 ENST00000449370.2
MAN1A2
mannosidase, alpha, class 1A, member 2
chr1_+_209878182 0.50 ENST00000367027.3
HSD11B1
hydroxysteroid (11-beta) dehydrogenase 1
chr7_-_143105941 0.49 ENST00000275815.3
EPHA1
EPH receptor A1
chr15_+_101417919 0.48 ENST00000561338.1
ALDH1A3
aldehyde dehydrogenase 1 family, member A3
chr3_+_189507432 0.44 ENST00000354600.5
TP63
tumor protein p63
chr9_+_124413873 0.41 ENST00000408936.3
DAB2IP
DAB2 interacting protein
chr4_-_90759440 0.39 ENST00000336904.3
SNCA
synuclein, alpha (non A4 component of amyloid precursor)
chr1_+_12524965 0.38 ENST00000471923.1
VPS13D
vacuolar protein sorting 13 homolog D (S. cerevisiae)
chr19_+_21106081 0.38 ENST00000300540.3
ENST00000595854.1
ENST00000601284.1
ENST00000328178.8
ENST00000599885.1
ENST00000596476.1
ENST00000345030.6
ZNF85
zinc finger protein 85
chr11_-_104827425 0.37 ENST00000393150.3
CASP4
caspase 4, apoptosis-related cysteine peptidase
chr11_+_63606373 0.35 ENST00000402010.2
ENST00000315032.8
ENST00000377809.4
ENST00000413835.2
ENST00000377810.3
MARK2
MAP/microtubule affinity-regulating kinase 2
chr3_-_196911002 0.33 ENST00000452595.1
DLG1
discs, large homolog 1 (Drosophila)
chr14_-_60952739 0.33 ENST00000555476.1
ENST00000321731.3
C14orf39
chromosome 14 open reading frame 39
chr19_+_21106028 0.33 ENST00000597314.1
ENST00000601924.1
ZNF85
zinc finger protein 85
chr3_-_18480173 0.33 ENST00000414509.1
SATB1
SATB homeobox 1
chr1_+_87012922 0.30 ENST00000263723.5
CLCA4
chloride channel accessory 4
chr11_+_71900703 0.30 ENST00000393681.2
FOLR1
folate receptor 1 (adult)
chr11_+_71900572 0.29 ENST00000312293.4
FOLR1
folate receptor 1 (adult)
chr6_+_43738444 0.29 ENST00000324450.6
ENST00000417285.2
ENST00000413642.3
ENST00000372055.4
ENST00000482630.2
ENST00000425836.2
ENST00000372064.4
ENST00000372077.4
ENST00000519767.1
VEGFA
vascular endothelial growth factor A
chr8_-_71157595 0.28 ENST00000519724.1
NCOA2
nuclear receptor coactivator 2
chr14_+_73706308 0.28 ENST00000554301.1
ENST00000555445.1
PAPLN
papilin, proteoglycan-like sulfated glycoprotein
chrX_-_15619076 0.28 ENST00000252519.3
ACE2
angiotensin I converting enzyme 2
chr11_-_46113756 0.27 ENST00000531959.1
PHF21A
PHD finger protein 21A
chr4_-_76957214 0.27 ENST00000306621.3
CXCL11
chemokine (C-X-C motif) ligand 11
chr1_-_152386732 0.27 ENST00000271835.3
CRNN
cornulin
chr1_+_154401791 0.27 ENST00000476006.1
IL6R
interleukin 6 receptor
chr4_-_57522673 0.27 ENST00000381255.3
ENST00000317745.7
ENST00000555760.2
ENST00000556614.2
HOPX
HOP homeobox
chr18_-_5396271 0.27 ENST00000579951.1
EPB41L3
erythrocyte membrane protein band 4.1-like 3
chr6_+_143447322 0.26 ENST00000458219.1
AIG1
androgen-induced 1
chr2_+_234668894 0.26 ENST00000305208.5
ENST00000608383.1
ENST00000360418.3
UGT1A8
UGT1A1
UDP glucuronosyltransferase 1 family, polypeptide A1
UDP glucuronosyltransferase 1 family, polypeptide A8
chr1_+_152730499 0.26 ENST00000368773.1
KPRP
keratinocyte proline-rich protein
chr6_+_43737939 0.26 ENST00000372067.3
VEGFA
vascular endothelial growth factor A
chr9_+_109685630 0.25 ENST00000451160.2
RP11-508N12.4
Uncharacterized protein
chr9_-_179018 0.25 ENST00000431099.2
ENST00000382447.4
ENST00000382389.1
ENST00000377447.3
ENST00000314367.10
ENST00000356521.4
ENST00000382393.1
ENST00000377400.4
CBWD1
COBW domain containing 1
chr8_-_8318847 0.25 ENST00000521218.1
CTA-398F10.2
CTA-398F10.2
chr4_+_169633310 0.25 ENST00000510998.1
PALLD
palladin, cytoskeletal associated protein
chr2_+_220143989 0.24 ENST00000336576.5
DNAJB2
DnaJ (Hsp40) homolog, subfamily B, member 2
chr2_+_138721850 0.24 ENST00000329366.4
ENST00000280097.3
HNMT
histamine N-methyltransferase
chr15_-_101817492 0.23 ENST00000528346.1
ENST00000531964.1
VIMP
VCP-interacting membrane protein
chr2_-_216878305 0.23 ENST00000263268.6
MREG
melanoregulin
chr4_+_37455536 0.23 ENST00000381980.4
ENST00000508175.1
C4orf19
chromosome 4 open reading frame 19
chr2_+_220144052 0.22 ENST00000425450.1
ENST00000392086.4
ENST00000421532.1
DNAJB2
DnaJ (Hsp40) homolog, subfamily B, member 2
chr18_+_42260861 0.22 ENST00000282030.5
SETBP1
SET binding protein 1
chr3_+_107364769 0.22 ENST00000449271.1
ENST00000425868.1
ENST00000449213.1
BBX
bobby sox homolog (Drosophila)
chr2_+_102928009 0.22 ENST00000404917.2
ENST00000447231.1
IL1RL1
interleukin 1 receptor-like 1
chr21_+_30503282 0.21 ENST00000399925.1
MAP3K7CL
MAP3K7 C-terminal like
chr1_+_46152886 0.21 ENST00000372025.4
TMEM69
transmembrane protein 69
chr7_+_138915102 0.21 ENST00000486663.1
UBN2
ubinuclein 2
chr13_-_46626847 0.21 ENST00000242848.4
ENST00000282007.3
ZC3H13
zinc finger CCCH-type containing 13
chr6_+_158733692 0.20 ENST00000367094.2
ENST00000367097.3
TULP4
tubby like protein 4
chr12_+_25205568 0.20 ENST00000548766.1
ENST00000556887.1
LRMP
lymphoid-restricted membrane protein
chr19_+_19626531 0.20 ENST00000507754.4
NDUFA13
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 13
chr17_+_61086917 0.20 ENST00000424789.2
ENST00000389520.4
TANC2
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
chr1_+_52682052 0.20 ENST00000371591.1
ZFYVE9
zinc finger, FYVE domain containing 9
chr11_+_10471836 0.20 ENST00000444303.2
AMPD3
adenosine monophosphate deaminase 3
chr5_-_126409159 0.20 ENST00000607731.1
ENST00000535381.1
ENST00000296662.5
ENST00000509733.3
C5orf63
chromosome 5 open reading frame 63
chr12_+_4130143 0.19 ENST00000543206.1
RP11-320N7.2
RP11-320N7.2
chr4_-_87281224 0.19 ENST00000395169.3
ENST00000395161.2
MAPK10
mitogen-activated protein kinase 10
chr12_+_25205446 0.19 ENST00000557489.1
ENST00000354454.3
ENST00000536173.1
LRMP
lymphoid-restricted membrane protein
chr10_+_24755416 0.19 ENST00000396446.1
ENST00000396445.1
ENST00000376451.2
KIAA1217
KIAA1217
chr4_+_79472975 0.18 ENST00000512373.1
ENST00000514171.1
ANXA3
annexin A3
chrX_-_117119243 0.18 ENST00000539496.1
ENST00000469946.1
KLHL13
kelch-like family member 13
chr5_-_159766528 0.18 ENST00000505287.2
CCNJL
cyclin J-like
chr1_-_226926864 0.17 ENST00000429204.1
ENST00000366784.1
ITPKB
inositol-trisphosphate 3-kinase B
chr16_+_12070567 0.17 ENST00000566228.1
SNX29
sorting nexin 29
chr5_-_159846399 0.17 ENST00000297151.4
SLU7
SLU7 splicing factor homolog (S. cerevisiae)
chr4_-_104021009 0.17 ENST00000509245.1
ENST00000296424.4
BDH2
3-hydroxybutyrate dehydrogenase, type 2
chr2_+_28718921 0.17 ENST00000327757.5
ENST00000422425.2
ENST00000404858.1
PLB1
phospholipase B1
chr4_-_72649763 0.16 ENST00000513476.1
GC
group-specific component (vitamin D binding protein)
chr18_-_52989217 0.16 ENST00000570287.2
TCF4
transcription factor 4
chr17_-_39553844 0.16 ENST00000251645.2
KRT31
keratin 31
chr5_+_140767452 0.16 ENST00000519479.1
PCDHGB4
protocadherin gamma subfamily B, 4
chr10_+_85933494 0.15 ENST00000372126.3
C10orf99
chromosome 10 open reading frame 99
chr5_+_67586465 0.15 ENST00000336483.5
PIK3R1
phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
chr5_-_125930929 0.15 ENST00000553117.1
ENST00000447989.2
ENST00000409134.3
ALDH7A1
aldehyde dehydrogenase 7 family, member A1
chr3_+_157828152 0.15 ENST00000476899.1
RSRC1
arginine/serine-rich coiled-coil 1
chr20_-_20693131 0.15 ENST00000202677.7
RALGAPA2
Ral GTPase activating protein, alpha subunit 2 (catalytic)
chr4_-_57547870 0.15 ENST00000381260.3
ENST00000420433.1
ENST00000554144.1
ENST00000557328.1
HOPX
HOP homeobox
chrX_-_80457385 0.15 ENST00000451455.1
ENST00000436386.1
ENST00000358130.2
HMGN5
high mobility group nucleosome binding domain 5
chr11_-_26744908 0.15 ENST00000533617.1
SLC5A12
solute carrier family 5 (sodium/monocarboxylate cotransporter), member 12
chr4_-_110723194 0.15 ENST00000394635.3
CFI
complement factor I
chr20_-_36152914 0.14 ENST00000397131.1
BLCAP
bladder cancer associated protein
chr9_+_70856397 0.14 ENST00000360171.6
CBWD3
COBW domain containing 3
chrX_+_55744228 0.14 ENST00000262850.7
RRAGB
Ras-related GTP binding B
chr1_-_115300579 0.14 ENST00000358528.4
ENST00000525132.1
CSDE1
cold shock domain containing E1, RNA-binding
chr11_-_7961141 0.14 ENST00000360759.3
OR10A3
olfactory receptor, family 10, subfamily A, member 3
chr7_+_18536090 0.14 ENST00000441986.1
HDAC9
histone deacetylase 9
chr1_+_43613612 0.14 ENST00000335282.4
FAM183A
family with sequence similarity 183, member A
chr1_-_54355430 0.14 ENST00000371399.1
ENST00000072644.1
ENST00000412288.1
YIPF1
Yip1 domain family, member 1
chr7_+_5468362 0.14 ENST00000608012.1
RP11-1275H24.3
RP11-1275H24.3
chr1_+_67773044 0.13 ENST00000262345.1
ENST00000371000.1
IL12RB2
interleukin 12 receptor, beta 2
chr13_-_103719196 0.13 ENST00000245312.3
SLC10A2
solute carrier family 10 (sodium/bile acid cotransporter), member 2
chr3_+_185046676 0.13 ENST00000428617.1
ENST00000443863.1
MAP3K13
mitogen-activated protein kinase kinase kinase 13
chr12_+_25205666 0.13 ENST00000547044.1
LRMP
lymphoid-restricted membrane protein
chr15_+_93447675 0.13 ENST00000536619.1
CHD2
chromodomain helicase DNA binding protein 2
chr8_+_145215928 0.13 ENST00000528919.1
MROH1
maestro heat-like repeat family member 1
chr6_+_46761118 0.13 ENST00000230588.4
MEP1A
meprin A, alpha (PABA peptide hydrolase)
chr4_-_57522598 0.13 ENST00000553379.2
HOPX
HOP homeobox
chr1_-_115300592 0.13 ENST00000261443.5
ENST00000534699.1
ENST00000339438.6
ENST00000529046.1
ENST00000525970.1
ENST00000369530.1
ENST00000530886.1
CSDE1
cold shock domain containing E1, RNA-binding
chr6_+_12958137 0.13 ENST00000457702.2
ENST00000379345.2
PHACTR1
phosphatase and actin regulator 1
chr6_+_25279759 0.12 ENST00000377969.3
LRRC16A
leucine rich repeat containing 16A
chr6_+_131958436 0.12 ENST00000357639.3
ENST00000543135.1
ENST00000427148.2
ENST00000358229.5
ENPP3
ectonucleotide pyrophosphatase/phosphodiesterase 3
chr13_+_25338290 0.12 ENST00000255324.5
ENST00000381921.1
ENST00000255325.6
RNF17
ring finger protein 17
chr3_-_112329110 0.12 ENST00000479368.1
CCDC80
coiled-coil domain containing 80
chr16_-_75498553 0.12 ENST00000569276.1
ENST00000357613.4
ENST00000561878.1
ENST00000566980.1
ENST00000567194.1
TMEM170A
RP11-77K12.1
transmembrane protein 170A
Uncharacterized protein
chr6_-_31830655 0.12 ENST00000375631.4
NEU1
sialidase 1 (lysosomal sialidase)
chr1_+_23345943 0.12 ENST00000400181.4
ENST00000542151.1
KDM1A
lysine (K)-specific demethylase 1A
chrX_-_54070388 0.12 ENST00000415025.1
PHF8
PHD finger protein 8
chr7_+_57509877 0.12 ENST00000420713.1
ZNF716
zinc finger protein 716
chr22_+_24407642 0.11 ENST00000454754.1
ENST00000263119.5
CABIN1
calcineurin binding protein 1
chr12_+_25205155 0.11 ENST00000550945.1
LRMP
lymphoid-restricted membrane protein
chr5_+_36608280 0.11 ENST00000513646.1
SLC1A3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr3_+_154741907 0.11 ENST00000492661.1
MME
membrane metallo-endopeptidase
chr19_-_9896672 0.11 ENST00000589412.1
ENST00000586814.1
ZNF846
zinc finger protein 846
chr2_-_165630264 0.11 ENST00000452626.1
COBLL1
cordon-bleu WH2 repeat protein-like 1
chr6_+_42584847 0.11 ENST00000372883.3
UBR2
ubiquitin protein ligase E3 component n-recognin 2
chr20_-_7921090 0.11 ENST00000378789.3
HAO1
hydroxyacid oxidase (glycolate oxidase) 1
chr6_+_148663729 0.11 ENST00000367467.3
SASH1
SAM and SH3 domain containing 1
chr1_-_220263096 0.11 ENST00000463953.1
ENST00000354807.3
ENST00000414869.2
ENST00000498237.2
ENST00000498791.2
ENST00000544404.1
ENST00000480959.2
ENST00000322067.7
BPNT1
3'(2'), 5'-bisphosphate nucleotidase 1
chr3_-_129612394 0.11 ENST00000505616.1
ENST00000426664.2
TMCC1
transmembrane and coiled-coil domain family 1
chr5_-_176433565 0.11 ENST00000428382.2
UIMC1
ubiquitin interaction motif containing 1
chr18_+_10526008 0.10 ENST00000542979.1
ENST00000322897.6
NAPG
N-ethylmaleimide-sensitive factor attachment protein, gamma
chr16_-_12070468 0.10 ENST00000538896.1
RP11-166B2.1
Putative NPIP-like protein LOC729978
chr13_-_79979919 0.10 ENST00000267229.7
RBM26
RNA binding motif protein 26
chr12_+_32638897 0.10 ENST00000531134.1
FGD4
FYVE, RhoGEF and PH domain containing 4
chr11_-_5537920 0.10 ENST00000380184.1
UBQLNL
ubiquilin-like
chrX_+_55744166 0.10 ENST00000374941.4
ENST00000414239.1
RRAGB
Ras-related GTP binding B
chr12_+_70219052 0.10 ENST00000552032.2
ENST00000547771.2
MYRFL
myelin regulatory factor-like
chr3_-_138048682 0.10 ENST00000383180.2
NME9
NME/NM23 family member 9
chr2_+_102927962 0.10 ENST00000233954.1
ENST00000393393.3
ENST00000410040.1
IL1RL1
IL18R1
interleukin 1 receptor-like 1
interleukin 18 receptor 1
chr16_-_25122785 0.10 ENST00000563962.1
ENST00000569920.1
RP11-449H11.1
RP11-449H11.1
chr5_-_88120083 0.10 ENST00000509373.1
MEF2C
myocyte enhancer factor 2C
chr11_-_110968081 0.10 ENST00000603154.1
RP11-89C3.4
RP11-89C3.4
chr11_-_65359947 0.10 ENST00000597463.1
AP001362.1
Uncharacterized protein
chr6_+_25279651 0.10 ENST00000329474.6
LRRC16A
leucine rich repeat containing 16A
chr12_-_118628350 0.09 ENST00000537952.1
ENST00000537822.1
TAOK3
TAO kinase 3
chr20_+_30697298 0.09 ENST00000398022.2
TM9SF4
transmembrane 9 superfamily protein member 4
chr1_-_155880672 0.09 ENST00000609492.1
ENST00000368322.3
RIT1
Ras-like without CAAX 1
chr19_+_12175596 0.09 ENST00000441304.2
ZNF844
zinc finger protein 844
chr18_+_19192228 0.09 ENST00000300413.5
ENST00000579618.1
ENST00000582475.1
SNRPD1
small nuclear ribonucleoprotein D1 polypeptide 16kDa
chr1_-_86848760 0.09 ENST00000460698.2
ODF2L
outer dense fiber of sperm tails 2-like
chr3_+_57875711 0.09 ENST00000442599.2
SLMAP
sarcolemma associated protein
chr12_+_25205628 0.09 ENST00000554942.1
LRMP
lymphoid-restricted membrane protein
chr1_-_17766198 0.09 ENST00000375436.4
RCC2
regulator of chromosome condensation 2
chr1_-_186430222 0.09 ENST00000391997.2
PDC
phosducin
chr6_-_137539651 0.09 ENST00000543628.1
IFNGR1
interferon gamma receptor 1
chr13_-_79979952 0.09 ENST00000438724.1
RBM26
RNA binding motif protein 26
chr9_-_69262509 0.09 ENST00000377449.1
ENST00000382399.4
ENST00000377439.1
ENST00000377441.1
ENST00000377457.5
CBWD6
COBW domain containing 6
chr2_+_185463093 0.08 ENST00000302277.6
ZNF804A
zinc finger protein 804A
chr10_+_78078088 0.08 ENST00000496424.2
C10orf11
chromosome 10 open reading frame 11
chr19_-_3500635 0.08 ENST00000250937.3
DOHH
deoxyhypusine hydroxylase/monooxygenase
chr3_-_180707306 0.08 ENST00000479269.1
DNAJC19
DnaJ (Hsp40) homolog, subfamily C, member 19
chr5_-_150467221 0.08 ENST00000522226.1
TNIP1
TNFAIP3 interacting protein 1
chr1_+_53480598 0.08 ENST00000430330.2
ENST00000408941.3
ENST00000478274.2
ENST00000484100.1
ENST00000435345.2
ENST00000488965.1
SCP2
sterol carrier protein 2
chr2_-_207078086 0.08 ENST00000442134.1
GPR1
G protein-coupled receptor 1
chr22_-_43010928 0.08 ENST00000348657.2
ENST00000252115.5
POLDIP3
polymerase (DNA-directed), delta interacting protein 3
chr6_+_80816342 0.08 ENST00000369760.4
ENST00000356489.5
ENST00000320393.6
BCKDHB
branched chain keto acid dehydrogenase E1, beta polypeptide
chr9_+_125703282 0.08 ENST00000373647.4
ENST00000402311.1
RABGAP1
RAB GTPase activating protein 1
chr12_+_19389814 0.08 ENST00000536974.1
PLEKHA5
pleckstrin homology domain containing, family A member 5
chr5_+_36606700 0.08 ENST00000416645.2
SLC1A3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr4_+_146539415 0.08 ENST00000281317.5
MMAA
methylmalonic aciduria (cobalamin deficiency) cblA type
chr4_-_140222358 0.07 ENST00000505036.1
ENST00000544855.1
ENST00000539002.1
NDUFC1
NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa
chr3_+_57875738 0.07 ENST00000417128.1
ENST00000438794.1
SLMAP
sarcolemma associated protein
chr1_-_95846556 0.07 ENST00000426881.2
RP11-14O19.2
RP11-14O19.2
chr18_-_12656715 0.07 ENST00000462226.1
ENST00000497844.2
ENST00000309836.5
ENST00000453447.2
SPIRE1
spire-type actin nucleation factor 1
chr22_-_22337146 0.07 ENST00000398793.2
TOP3B
topoisomerase (DNA) III beta
chr1_-_95846528 0.07 ENST00000427695.3
RP11-14O19.2
RP11-14O19.2
chr3_-_50375657 0.07 ENST00000395126.3
RASSF1
Ras association (RalGDS/AF-6) domain family member 1
chr9_+_96846740 0.07 ENST00000288976.3
PTPDC1
protein tyrosine phosphatase domain containing 1
chr14_-_64846033 0.07 ENST00000556556.1
CTD-2555O16.1
CTD-2555O16.1
chr18_-_53069419 0.07 ENST00000570177.2
TCF4
transcription factor 4
chr1_+_22379179 0.07 ENST00000315554.8
ENST00000421089.2
CDC42
cell division cycle 42
chr1_+_23345930 0.07 ENST00000356634.3
KDM1A
lysine (K)-specific demethylase 1A
chr4_-_68829226 0.07 ENST00000396188.2
TMPRSS11A
transmembrane protease, serine 11A
chr11_+_22688615 0.07 ENST00000533363.1
GAS2
growth arrest-specific 2
chr14_-_38028689 0.07 ENST00000553425.1
RP11-356O9.2
RP11-356O9.2

Network of associatons between targets according to the STRING database.

First level regulatory network of HOXA10_HOXB9

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.9 GO:0070175 positive regulation of enamel mineralization(GO:0070175)
0.5 1.5 GO:0060278 regulation of ovulation(GO:0060278) positive regulation of ovulation(GO:0060279)
0.4 1.6 GO:0007499 ectoderm and mesoderm interaction(GO:0007499)
0.3 1.1 GO:0050717 positive regulation of interleukin-1 alpha secretion(GO:0050717)
0.2 0.6 GO:0060490 orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490)
0.2 0.6 GO:0061713 neural crest cell migration involved in heart formation(GO:0003147) anterior neural tube closure(GO:0061713)
0.2 0.5 GO:1903570 regulation of protein kinase D signaling(GO:1903570) positive regulation of protein kinase D signaling(GO:1903572)
0.2 2.2 GO:1904352 positive regulation of protein catabolic process in the vacuole(GO:1904352)
0.1 0.5 GO:0060166 olfactory pit development(GO:0060166)
0.1 0.3 GO:1904017 cellular response to Thyroglobulin triiodothyronine(GO:1904017)
0.1 0.5 GO:1903644 regulation of chaperone-mediated protein folding(GO:1903644)
0.1 0.3 GO:0002384 hepatic immune response(GO:0002384)
0.1 0.4 GO:0043553 vascular endothelial growth factor receptor-2 signaling pathway(GO:0036324) negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.1 0.7 GO:2000660 negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
0.1 0.4 GO:0051622 negative regulation of dopamine uptake involved in synaptic transmission(GO:0051585) norepinephrine uptake(GO:0051620) regulation of norepinephrine uptake(GO:0051621) negative regulation of norepinephrine uptake(GO:0051622) negative regulation of catecholamine uptake involved in synaptic transmission(GO:0051945) regulation of glutathione peroxidase activity(GO:1903282) positive regulation of glutathione peroxidase activity(GO:1903284) positive regulation of hydrogen peroxide catabolic process(GO:1903285) positive regulation of peroxidase activity(GO:2000470)
0.1 0.5 GO:1904381 Golgi apparatus mannose trimming(GO:1904381)
0.1 0.5 GO:0071494 cellular response to UV-C(GO:0071494)
0.1 0.3 GO:0003051 angiotensin-mediated drinking behavior(GO:0003051) receptor-mediated virion attachment to host cell(GO:0046813)
0.1 0.3 GO:0070980 biphenyl catabolic process(GO:0070980)
0.0 0.3 GO:0038172 interleukin-33-mediated signaling pathway(GO:0038172)
0.0 0.4 GO:1903265 positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
0.0 0.9 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.0 0.1 GO:0030505 inorganic diphosphate transport(GO:0030505)
0.0 0.2 GO:0001692 histamine metabolic process(GO:0001692)
0.0 0.2 GO:0031456 glycine betaine biosynthetic process from choline(GO:0019285) glycine betaine metabolic process(GO:0031455) glycine betaine biosynthetic process(GO:0031456)
0.0 0.1 GO:0035574 histone H4-K20 demethylation(GO:0035574)
0.0 0.3 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.0 0.3 GO:1903764 regulation of potassium ion export across plasma membrane(GO:1903764)
0.0 0.2 GO:1990253 cellular response to leucine starvation(GO:1990253)
0.0 0.3 GO:0002175 protein localization to paranode region of axon(GO:0002175)
0.0 0.1 GO:0072356 chromosome passenger complex localization to kinetochore(GO:0072356)
0.0 0.6 GO:0097264 self proteolysis(GO:0097264)
0.0 0.1 GO:0071233 cellular response to leucine(GO:0071233)
0.0 0.2 GO:0006196 AMP catabolic process(GO:0006196)
0.0 0.6 GO:0001542 ovulation from ovarian follicle(GO:0001542)
0.0 0.2 GO:0046098 guanine metabolic process(GO:0046098)
0.0 0.2 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.2 GO:0003138 primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
0.0 0.3 GO:0043950 positive regulation of cAMP-mediated signaling(GO:0043950)
0.0 0.6 GO:0097296 activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097296)
0.0 0.2 GO:0001781 neutrophil apoptotic process(GO:0001781) regulation of neutrophil apoptotic process(GO:0033029)
0.0 0.1 GO:0046116 queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
0.0 0.1 GO:1904211 membrane protein proteolysis involved in retrograde protein transport, ER to cytosol(GO:1904211)
0.0 0.2 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.0 0.2 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.0 0.5 GO:0006704 glucocorticoid biosynthetic process(GO:0006704)
0.0 0.1 GO:0009236 cobalamin biosynthetic process(GO:0009236)
0.0 0.5 GO:0001829 trophectodermal cell differentiation(GO:0001829)
0.0 0.2 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
0.0 0.2 GO:0070777 gamma-aminobutyric acid biosynthetic process(GO:0009449) D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.0 0.1 GO:0052250 modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032)
0.0 0.1 GO:0009441 glycolate metabolic process(GO:0009441)
0.0 0.1 GO:0018283 metal incorporation into metallo-sulfur cluster(GO:0018282) iron incorporation into metallo-sulfur cluster(GO:0018283)
0.0 0.6 GO:0001701 in utero embryonic development(GO:0001701)
0.0 0.1 GO:0070537 histone H2A K63-linked deubiquitination(GO:0070537)
0.0 0.2 GO:2000344 positive regulation of acrosome reaction(GO:2000344)
0.0 0.1 GO:1902498 regulation of protein autoubiquitination(GO:1902498)
0.0 0.2 GO:0007258 JUN phosphorylation(GO:0007258)
0.0 0.0 GO:0006540 glutamate decarboxylation to succinate(GO:0006540)
0.0 0.1 GO:1902268 negative regulation of polyamine transmembrane transport(GO:1902268)
0.0 0.1 GO:0008612 peptidyl-lysine modification to peptidyl-hypusine(GO:0008612)
0.0 0.1 GO:0032380 regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
0.0 0.1 GO:0051835 positive regulation of synapse structural plasticity(GO:0051835) actin filament branching(GO:0090135)
0.0 0.1 GO:0071492 cellular response to UV-A(GO:0071492)
0.0 0.8 GO:0018149 peptide cross-linking(GO:0018149)
0.0 0.1 GO:0035873 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.5 GO:0043512 inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.2 1.6 GO:0097179 protease inhibitor complex(GO:0097179)
0.2 0.6 GO:0060187 cell pole(GO:0060187)
0.1 0.4 GO:1990032 parallel fiber(GO:1990032)
0.1 0.7 GO:0043083 synaptic cleft(GO:0043083)
0.1 0.3 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.1 0.4 GO:0097169 AIM2 inflammasome complex(GO:0097169)
0.0 2.2 GO:0005605 basal lamina(GO:0005605)
0.0 0.2 GO:1990131 Gtr1-Gtr2 GTPase complex(GO:1990131)
0.0 0.6 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.0 0.4 GO:0097427 microtubule bundle(GO:0097427)
0.0 0.2 GO:1990578 perinuclear endoplasmic reticulum membrane(GO:1990578)
0.0 0.3 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.0 1.2 GO:0001533 cornified envelope(GO:0001533)
0.0 2.0 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 0.1 GO:0031592 centrosomal corona(GO:0031592)
0.0 0.3 GO:0012505 endomembrane system(GO:0012505)
0.0 0.1 GO:0034715 pICln-Sm protein complex(GO:0034715)
0.0 0.3 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.5 GO:0070699 type II activin receptor binding(GO:0070699)
0.2 0.7 GO:0005150 interleukin-1, Type I receptor binding(GO:0005150)
0.2 0.5 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
0.1 0.6 GO:0061714 folic acid receptor activity(GO:0061714)
0.1 0.3 GO:0002113 interleukin-33 binding(GO:0002113)
0.1 1.6 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.1 0.5 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.1 0.3 GO:0070119 ciliary neurotrophic factor binding(GO:0070119)
0.1 0.4 GO:0060961 phospholipase D inhibitor activity(GO:0060961)
0.1 1.1 GO:0089720 caspase binding(GO:0089720)
0.1 0.3 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.1 0.2 GO:0061752 telomeric repeat-containing RNA binding(GO:0061752)
0.1 0.4 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.1 0.3 GO:0010861 thyroid hormone receptor activator activity(GO:0010861) thyroid hormone receptor coactivator activity(GO:0030375)
0.1 0.2 GO:1902271 D3 vitamins binding(GO:1902271)
0.0 0.2 GO:0003858 3-hydroxybutyrate dehydrogenase activity(GO:0003858)
0.0 0.5 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 0.2 GO:0000386 second spliceosomal transesterification activity(GO:0000386)
0.0 0.1 GO:0016899 oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor(GO:0016899)
0.0 0.1 GO:0008441 3'(2'),5'-bisphosphate nucleotidase activity(GO:0008441)
0.0 0.1 GO:0035575 histone demethylase activity (H4-K20 specific)(GO:0035575)
0.0 0.3 GO:0008241 peptidyl-dipeptidase activity(GO:0008241)
0.0 0.2 GO:0050253 retinyl-palmitate esterase activity(GO:0050253)
0.0 0.5 GO:0070324 thyroid hormone binding(GO:0070324)
0.0 0.6 GO:0050700 CARD domain binding(GO:0050700)
0.0 0.1 GO:0070538 oleic acid binding(GO:0070538)
0.0 0.1 GO:0003863 alpha-ketoacid dehydrogenase activity(GO:0003826) 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity(GO:0003863)
0.0 0.1 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
0.0 0.4 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0 0.2 GO:0004882 androgen receptor activity(GO:0004882)
0.0 0.3 GO:0097016 L27 domain binding(GO:0097016)
0.0 0.1 GO:0035529 NADH pyrophosphatase activity(GO:0035529)
0.0 0.1 GO:0031071 cysteine desulfurase activity(GO:0031071)
0.0 0.2 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.2 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.0 0.1 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.0 0.2 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.0 0.1 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.0 0.1 GO:0032427 GBD domain binding(GO:0032427)
0.0 0.2 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.0 0.1 GO:0070728 leucine binding(GO:0070728)
0.0 0.2 GO:0004705 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 0.1 GO:0052796 exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.0 0.1 GO:0004906 interferon-gamma receptor activity(GO:0004906)
0.0 0.3 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 0.4 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.1 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.0 0.1 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.0 0.4 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.0 0.1 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.0 0.2 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.1 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.1 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 0.5 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 1.3 PID ALK1 PATHWAY ALK1 signaling events
0.0 2.1 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 0.9 PID TRAIL PATHWAY TRAIL signaling pathway
0.0 1.6 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.2 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.0 0.3 ST STAT3 PATHWAY STAT3 Pathway
0.0 0.3 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.7 PID IL1 PATHWAY IL1-mediated signaling events
0.0 1.4 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 0.1 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.5 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.1 1.1 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 0.5 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.8 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.7 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.0 0.3 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.3 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.5 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling