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SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for HOXA13

Z-value: 0.47

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Transcription factors associated with HOXA13

Gene Symbol Gene ID Gene Info
ENSG00000106031.6 homeobox A13

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HOXA13hg19_v2_chr7_-_27239703_272397250.802.4e-05Click!

Activity profile of HOXA13 motif

Sorted Z-values of HOXA13 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr20_+_37554955 1.40 ENST00000217429.4
family with sequence similarity 83, member D
chr2_-_225811747 1.07 ENST00000409592.3
dedicator of cytokinesis 10
chr4_-_40516560 0.93 ENST00000513473.1
RNA binding motif protein 47
chr3_+_160117062 0.77 ENST00000497311.1
structural maintenance of chromosomes 4
chr2_+_37571717 0.69 ENST00000338415.3
ENST00000404976.1
glutaminyl-peptide cyclotransferase
chr8_-_95274536 0.63 ENST00000297596.2
ENST00000396194.2
GTP binding protein overexpressed in skeletal muscle
chr2_-_25100893 0.61 ENST00000433852.1
adenylate cyclase 3
chrX_-_20236970 0.60 ENST00000379548.4
ribosomal protein S6 kinase, 90kDa, polypeptide 3
chr12_-_116714564 0.60 ENST00000548743.1
mediator complex subunit 13-like
chr5_+_169010638 0.57 ENST00000265295.4
ENST00000506574.1
ENST00000515224.1
ENST00000508247.1
ENST00000513941.1
spindle apparatus coiled-coil protein 1
chr13_+_34392200 0.56 ENST00000434425.1
replication factor C (activator 1) 3, 38kDa
chr9_+_67977438 0.55 ENST00000456982.1
Protein LOC644249
chr1_+_199996733 0.55 ENST00000236914.3
nuclear receptor subfamily 5, group A, member 2
chr4_+_106631966 0.55 ENST00000360505.5
ENST00000510865.1
ENST00000509336.1
glutathione S-transferase, C-terminal domain containing
chr4_+_48485341 0.55 ENST00000273861.4
solute carrier family 10, member 4
chr17_+_17685422 0.54 ENST00000395774.1
retinoic acid induced 1
chr12_+_20963632 0.52 ENST00000540853.1
ENST00000261196.2
solute carrier organic anion transporter family, member 1B3
chr15_+_85523671 0.52 ENST00000310298.4
ENST00000557957.1
phosphodiesterase 8A
chr16_+_19619083 0.52 ENST00000538552.1
chromosome 16 open reading frame 62
chrX_-_19688475 0.51 ENST00000541422.1
SH3-domain kinase binding protein 1
chr2_+_37571845 0.50 ENST00000537448.1
glutaminyl-peptide cyclotransferase
chr17_+_57233087 0.50 ENST00000578777.1
ENST00000577457.1
ENST00000582995.1
proline rich 11
chr5_-_58571935 0.49 ENST00000503258.1
phosphodiesterase 4D, cAMP-specific
chr1_+_222886694 0.47 ENST00000426638.1
ENST00000537020.1
ENST00000539697.1
BRO1 domain and CAAX motif containing
chr17_-_46806540 0.47 ENST00000290295.7
homeobox B13
chr5_+_138210919 0.47 ENST00000522013.1
ENST00000520260.1
ENST00000523298.1
ENST00000520865.1
ENST00000519634.1
ENST00000517533.1
ENST00000523685.1
ENST00000519768.1
ENST00000517656.1
ENST00000521683.1
ENST00000521640.1
ENST00000519116.1
catenin (cadherin-associated protein), alpha 1, 102kDa
chr11_+_111896090 0.44 ENST00000393051.1
dihydrolipoamide S-acetyltransferase
chr13_+_34392185 0.44 ENST00000380071.3
replication factor C (activator 1) 3, 38kDa
chr20_-_25320367 0.44 ENST00000450393.1
ENST00000491682.1
abhydrolase domain containing 12
chr12_-_47473425 0.44 ENST00000550413.1
adhesion molecule with Ig-like domain 2
chr17_-_76824975 0.43 ENST00000586066.2
ubiquitin specific peptidase 36
chr16_+_53483983 0.43 ENST00000544545.1
retinoblastoma-like 2 (p130)
chr14_-_80678512 0.43 ENST00000553968.1
deiodinase, iodothyronine, type II
chr3_-_123339343 0.42 ENST00000578202.1
myosin light chain kinase
chr2_+_109223595 0.42 ENST00000410093.1
LIM and senescent cell antigen-like domains 1
chr3_+_113667354 0.42 ENST00000491556.1
zinc finger, DHHC-type containing 23
chr9_+_137979506 0.41 ENST00000539529.1
ENST00000392991.4
ENST00000371793.3
olfactomedin 1
chr7_-_27196267 0.41 ENST00000242159.3
homeobox A7
chr3_-_8811288 0.41 ENST00000316793.3
ENST00000431493.1
oxytocin receptor
chr16_-_28192360 0.41 ENST00000570033.1
exportin 6
chr19_+_36545781 0.41 ENST00000388999.3
WD repeat domain 62
chr11_+_111896320 0.41 ENST00000531306.1
ENST00000537636.1
dihydrolipoamide S-acetyltransferase
chr2_+_7073174 0.40 ENST00000416587.1
ring finger protein 144A
chr19_+_36545833 0.40 ENST00000401500.2
ENST00000270301.7
ENST00000427823.2
WD repeat domain 62
chr15_-_88799661 0.39 ENST00000360948.2
ENST00000357724.2
ENST00000355254.2
ENST00000317501.3
neurotrophic tyrosine kinase, receptor, type 3
chr17_-_46688334 0.39 ENST00000239165.7
homeobox B7
chr11_+_61891445 0.39 ENST00000394818.3
ENST00000533896.1
ENST00000278849.4
inner centromere protein antigens 135/155kDa
chr5_-_146781153 0.39 ENST00000520473.1
dihydropyrimidinase-like 3
chr15_+_59908633 0.38 ENST00000559626.1
glucosaminyl (N-acetyl) transferase 3, mucin type
chr17_+_55183261 0.37 ENST00000576295.1
A kinase (PRKA) anchor protein 1
chr16_-_18908196 0.36 ENST00000565324.1
ENST00000561947.1
SMG1 phosphatidylinositol 3-kinase-related kinase
chr2_+_174219548 0.36 ENST00000347703.3
ENST00000392567.2
ENST00000306721.3
ENST00000410101.3
ENST00000410019.3
cell division cycle associated 7
chr1_+_173793777 0.36 ENST00000239457.5
aspartyl-tRNA synthetase 2, mitochondrial
chr12_+_97300995 0.36 ENST00000266742.4
ENST00000429527.2
ENST00000554226.1
ENST00000557478.1
ENST00000557092.1
ENST00000411739.2
ENST00000553609.1
neural precursor cell expressed, developmentally down-regulated 1
chr4_+_141178440 0.35 ENST00000394205.3
short coiled-coil protein
chr11_-_115127611 0.35 ENST00000545094.1
cell adhesion molecule 1
chr17_-_57158523 0.35 ENST00000581468.1
tripartite motif containing 37
chr17_-_40170506 0.35 ENST00000589773.1
ENST00000590348.1
DnaJ (Hsp40) homolog, subfamily C, member 7
chr3_-_123339418 0.35 ENST00000583087.1
myosin light chain kinase
chr11_+_34999328 0.34 ENST00000526309.1
pyruvate dehydrogenase complex, component X
chr12_+_47473369 0.33 ENST00000546455.1
PC-esterase domain containing 1B
chrX_-_10645724 0.33 ENST00000413894.1
midline 1 (Opitz/BBB syndrome)
chr14_+_56078695 0.33 ENST00000416613.1
kinectin 1 (kinesin receptor)
chr19_+_34887220 0.33 ENST00000592740.1
Uncharacterized protein
chr12_+_45609862 0.32 ENST00000423947.3
ENST00000435642.1
anoctamin 6
chr2_-_133429091 0.32 ENST00000345008.6
LY6/PLAUR domain containing 1
chrY_+_2709527 0.32 ENST00000250784.8
ribosomal protein S4, Y-linked 1
chr12_+_45609797 0.32 ENST00000425752.2
anoctamin 6
chr3_+_99979828 0.31 ENST00000485687.1
ENST00000344949.5
ENST00000394144.4
TBC1 domain family, member 23
chr12_+_20963647 0.30 ENST00000381545.3
solute carrier organic anion transporter family, member 1B3
chr2_+_32390925 0.30 ENST00000440718.1
ENST00000379343.2
ENST00000282587.5
ENST00000435660.1
ENST00000538303.1
ENST00000357055.3
ENST00000406369.1
solute carrier family 30 (zinc transporter), member 6
chr1_+_199996702 0.30 ENST00000367362.3
nuclear receptor subfamily 5, group A, member 2
chr1_+_100818009 0.29 ENST00000370125.2
ENST00000361544.6
ENST00000370124.3
cell division cycle 14A
chr1_-_207224307 0.29 ENST00000315927.4
YOD1 deubiquitinase
chr22_+_45714301 0.29 ENST00000427777.1
family with sequence similarity 118, member A
chr3_-_118753716 0.29 ENST00000393775.2
immunoglobulin superfamily, member 11
chrX_+_9431324 0.29 ENST00000407597.2
ENST00000424279.1
ENST00000536365.1
ENST00000441088.1
ENST00000380961.1
ENST00000415293.1
transducin (beta)-like 1X-linked
chr19_+_35773242 0.28 ENST00000222304.3
hepcidin antimicrobial peptide
chr3_+_57882024 0.28 ENST00000494088.1
sarcolemma associated protein
chr8_-_110346614 0.28 ENST00000239690.4
NudC domain containing 1
chr2_+_182756615 0.27 ENST00000431877.2
ENST00000320370.7
sperm specific antigen 2
chr10_-_30638090 0.27 ENST00000421701.1
ENST00000263063.4
mitochondrial poly(A) polymerase
chr3_+_99986036 0.27 ENST00000471098.1
TBC1 domain family, member 23
chr5_-_78808617 0.27 ENST00000282260.6
ENST00000508576.1
ENST00000535690.1
homer homolog 1 (Drosophila)
chr3_-_118753626 0.26 ENST00000489689.1
immunoglobulin superfamily, member 11
chr17_-_17480779 0.26 ENST00000395782.1
phosphatidylethanolamine N-methyltransferase
chr1_-_150208291 0.26 ENST00000533654.1
acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
chr1_-_230991747 0.26 ENST00000523410.1
chromosome 1 open reading frame 198
chr10_-_113943447 0.26 ENST00000369425.1
ENST00000348367.4
ENST00000423155.1
glycerol-3-phosphate acyltransferase, mitochondrial
chr8_-_29939933 0.25 ENST00000522794.1
transmembrane protein 66
chr15_+_77713299 0.25 ENST00000559099.1
high mobility group 20A
chr1_-_150208498 0.25 ENST00000314136.8
acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
chr22_+_18632666 0.25 ENST00000215794.7
ubiquitin specific peptidase 18
chr5_-_40755987 0.25 ENST00000337702.4
tetratricopeptide repeat domain 33
chr7_-_73256838 0.25 ENST00000297873.4
Williams Beuren syndrome chromosome region 27
chr14_-_20774092 0.25 ENST00000423949.2
ENST00000553828.1
ENST00000258821.3
tetratricopeptide repeat domain 5
chr15_+_71228826 0.24 ENST00000558456.1
ENST00000560158.2
ENST00000558808.1
ENST00000559806.1
ENST00000559069.1
leucine rich repeat containing 49
chr1_-_150208412 0.24 ENST00000532744.1
ENST00000369114.5
ENST00000369115.2
ENST00000369116.4
acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
chr5_+_133861790 0.23 ENST00000395003.1
jade family PHD finger 2
chr1_+_84609944 0.23 ENST00000370685.3
protein kinase, cAMP-dependent, catalytic, beta
chr2_+_33359473 0.23 ENST00000432635.1
latent transforming growth factor beta binding protein 1
chr3_-_149093499 0.23 ENST00000472441.1
transmembrane 4 L six family member 1
chr20_+_19870167 0.23 ENST00000440354.2
Ras and Rab interactor 2
chr15_+_52155001 0.22 ENST00000544199.1
tropomodulin 3 (ubiquitous)
chr17_-_40021656 0.22 ENST00000319121.3
kelch-like family member 11
chr7_-_69062391 0.22 ENST00000436600.2
RP5-942I16.1
chr15_-_55881135 0.22 ENST00000302000.6
pygopus family PHD finger 1
chr2_-_74007095 0.22 ENST00000452812.1
dual specificity phosphatase 11 (RNA/RNP complex 1-interacting)
chr4_+_122722466 0.22 ENST00000243498.5
ENST00000379663.3
ENST00000509800.1
exosome component 9
chr15_-_99789736 0.21 ENST00000560235.1
ENST00000394132.2
ENST00000560860.1
ENST00000558078.1
ENST00000394136.1
ENST00000262074.4
ENST00000558613.1
ENST00000394130.1
ENST00000560772.1
tetratricopeptide repeat domain 23
chr6_+_121756809 0.20 ENST00000282561.3
gap junction protein, alpha 1, 43kDa
chr9_-_116172617 0.20 ENST00000374169.3
polymerase (DNA directed), epsilon 3, accessory subunit
chr19_-_14530112 0.20 ENST00000592632.1
ENST00000589675.1
DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A
chr1_-_150208320 0.20 ENST00000534220.1
acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
chr13_+_78315466 0.20 ENST00000314070.5
ENST00000462234.1
SLAIN motif family, member 1
chrX_+_123097014 0.20 ENST00000394478.1
stromal antigen 2
chr5_+_140180635 0.20 ENST00000522353.2
ENST00000532566.2
protocadherin alpha 3
chr20_+_55204351 0.19 ENST00000201031.2
transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)
chrX_-_135962923 0.19 ENST00000565438.1
RNA binding motif protein, X-linked
chr16_-_66764119 0.19 ENST00000569320.1
dynein, cytoplasmic 1, light intermediate chain 2
chr9_-_139137648 0.19 ENST00000358701.5
quiescin Q6 sulfhydryl oxidase 2
chr6_+_134273300 0.19 ENST00000416965.1
TBP-like 1
chrX_-_135962876 0.19 ENST00000431446.3
ENST00000570135.1
ENST00000320676.7
ENST00000562646.1
RNA binding motif protein, X-linked
chr3_+_101498269 0.19 ENST00000491511.2
neurexophilin and PC-esterase domain family, member 3
chr4_-_17513604 0.19 ENST00000505710.1
quinoid dihydropteridine reductase
chr2_+_33359687 0.18 ENST00000402934.1
ENST00000404525.1
ENST00000407925.1
latent transforming growth factor beta binding protein 1
chr1_-_150208363 0.18 ENST00000436748.2
acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
chr17_-_15496722 0.18 ENST00000472534.1
CMT1A duplicated region transcript 1
chr10_-_13544945 0.18 ENST00000378605.3
ENST00000341083.3
BEN domain containing 7
chr10_+_90750493 0.18 ENST00000357339.2
ENST00000355279.2
Fas cell surface death receptor
chr5_+_95997885 0.18 ENST00000511097.2
calpastatin
chr9_-_21305312 0.17 ENST00000259555.4
interferon, alpha 5
chr19_-_6279932 0.17 ENST00000252674.7
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 1
chr10_-_52383644 0.17 ENST00000361781.2
sphingomyelin synthase 1
chr14_-_71067360 0.17 ENST00000554963.1
ENST00000430055.2
ENST00000440435.2
ENST00000256379.5
mediator complex subunit 6
chr9_-_98269481 0.17 ENST00000418258.1
ENST00000553011.1
ENST00000551845.1
patched 1
chr16_+_66914264 0.17 ENST00000311765.2
ENST00000568869.1
ENST00000561704.1
ENST00000568398.1
ENST00000566776.1
pyruvate dehyrogenase phosphatase catalytic subunit 2
chr5_+_68860949 0.16 ENST00000507595.1
general transcription factor IIH, polypeptide 2C
chr3_+_111578027 0.16 ENST00000431670.2
ENST00000412622.1
pleckstrin homology-like domain, family B, member 2
chr2_+_33359646 0.16 ENST00000390003.4
ENST00000418533.2
latent transforming growth factor beta binding protein 1
chr3_-_118753792 0.16 ENST00000480431.1
immunoglobulin superfamily, member 11
chr1_+_153631130 0.16 ENST00000368685.5
SNAP-associated protein
chr4_-_128887069 0.16 ENST00000541133.1
ENST00000296468.3
ENST00000513559.1
major facilitator superfamily domain containing 8
chr5_-_79287060 0.16 ENST00000512560.1
ENST00000509852.1
ENST00000512528.1
metaxin 3
chrX_+_100878079 0.16 ENST00000471229.2
armadillo repeat containing, X-linked 3
chr17_+_77030267 0.15 ENST00000581774.1
C1q and tumor necrosis factor related protein 1
chr16_-_1538765 0.15 ENST00000447419.2
ENST00000440447.2
pentraxin 4, long
chr2_+_64681103 0.15 ENST00000464281.1
lectin, galactoside-binding-like
chr12_-_4647606 0.15 ENST00000261250.3
ENST00000541014.1
ENST00000545746.1
ENST00000542080.1
chromosome 12 open reading frame 4
chr17_-_39538550 0.15 ENST00000394001.1
keratin 34
chr14_+_50234309 0.15 ENST00000298307.5
kelch domain containing 2
chr10_+_92631709 0.15 ENST00000413330.1
ENST00000277882.3
ribonuclease P/MRP 30kDa subunit
chr7_-_151511911 0.15 ENST00000392801.2
protein kinase, AMP-activated, gamma 2 non-catalytic subunit
chr3_+_129159039 0.14 ENST00000507564.1
ENST00000431818.2
ENST00000504021.1
ENST00000349441.2
ENST00000348417.2
ENST00000440957.2
intraflagellar transport 122 homolog (Chlamydomonas)
chr19_+_49497121 0.14 ENST00000413176.2
RuvB-like AAA ATPase 2
chr1_+_179050512 0.14 ENST00000367627.3
torsin family 3, member A
chrX_-_38186775 0.14 ENST00000339363.3
ENST00000309513.3
ENST00000338898.3
ENST00000342811.3
ENST00000378505.2
retinitis pigmentosa GTPase regulator
chr2_-_169104651 0.14 ENST00000355999.4
serine threonine kinase 39
chr14_+_74353320 0.14 ENST00000540593.1
ENST00000555730.1
zinc finger protein 410
chr8_+_26150628 0.14 ENST00000523925.1
ENST00000315985.7
protein phosphatase 2, regulatory subunit B, alpha
chr3_-_160117035 0.14 ENST00000489004.1
ENST00000496589.1
intraflagellar transport 80 homolog (Chlamydomonas)
chr13_+_78315528 0.14 ENST00000496045.1
SLAIN motif family, member 1
chr1_-_155948890 0.14 ENST00000471589.1
Rho/Rac guanine nucleotide exchange factor (GEF) 2
chr7_+_129015671 0.13 ENST00000466993.1
adenosylhomocysteinase-like 2
chr7_-_23145288 0.13 ENST00000419813.1
KLHL7 antisense RNA 1 (head to head)
chr14_-_92414294 0.13 ENST00000554468.1
fibulin 5
chr17_+_33895090 0.13 ENST00000592381.1
RP11-1094M14.11
chr6_+_4706368 0.13 ENST00000328908.5
chromodomain protein, Y-like
chr19_+_49496782 0.13 ENST00000601968.1
ENST00000596837.1
RuvB-like AAA ATPase 2
chr17_+_16284604 0.13 ENST00000395839.1
ENST00000395837.1
ubiquitin B
chr1_+_171750776 0.13 ENST00000458517.1
ENST00000362019.3
ENST00000367737.5
ENST00000361735.3
methyltransferase like 13
chr9_-_130889990 0.12 ENST00000449878.1
prostaglandin E synthase 2
chr13_+_78315295 0.12 ENST00000351546.3
SLAIN motif family, member 1
chr3_+_57882061 0.12 ENST00000461354.1
ENST00000466255.1
sarcolemma associated protein
chr19_-_14529847 0.12 ENST00000590239.1
ENST00000590696.1
ENST00000591275.1
ENST00000586993.1
DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A
chr4_+_128702969 0.12 ENST00000508776.1
ENST00000439123.2
heat shock 70kDa protein 4-like
chr14_-_92414055 0.12 ENST00000342058.4
fibulin 5
chr13_+_78315348 0.11 ENST00000441784.1
SLAIN motif family, member 1
chr19_+_54369434 0.11 ENST00000421337.1
myeloid-associated differentiation marker
chr3_-_170587974 0.11 ENST00000463836.1
ribosomal protein L22-like 1
chr3_-_170587815 0.11 ENST00000466674.1
ribosomal protein L22-like 1
chr1_-_217804377 0.11 ENST00000366935.3
ENST00000366934.3
G patch domain containing 2
chr2_+_26256938 0.11 ENST00000264710.4
RAB10, member RAS oncogene family
chr12_+_45609893 0.11 ENST00000320560.8
anoctamin 6
chrX_+_117480036 0.11 ENST00000371822.5
ENST00000254029.3
ENST00000371825.3
WD repeat domain 44
chr5_-_75008244 0.11 ENST00000510798.1
ENST00000446329.2
POC5 centriolar protein
chr19_+_36426452 0.11 ENST00000588831.1
leucine rich repeat and fibronectin type III domain containing 3
chr12_-_53074182 0.11 ENST00000252244.3
keratin 1
chr8_-_63998590 0.11 ENST00000260116.4
tocopherol (alpha) transfer protein
chr9_-_98269699 0.11 ENST00000429896.2
patched 1
chr9_-_2844058 0.11 ENST00000397885.2
KIAA0020
chr20_+_37590942 0.10 ENST00000373325.2
ENST00000252011.3
ENST00000373323.4
DEAH (Asp-Glu-Ala-His) box polypeptide 35
chr8_+_94710789 0.10 ENST00000523475.1
family with sequence similarity 92, member A1
chr3_-_160116995 0.10 ENST00000465537.1
ENST00000486856.1
ENST00000468218.1
ENST00000478370.1
intraflagellar transport 80 homolog (Chlamydomonas)
chr11_+_101983176 0.10 ENST00000524575.1
Yes-associated protein 1
chr14_+_24540154 0.10 ENST00000559778.1
ENST00000560761.1
ENST00000557889.1
copine VI (neuronal)
chr3_-_123680246 0.10 ENST00000488653.2
coiled-coil domain containing 14
chr17_+_78234625 0.10 ENST00000508628.2
ENST00000582970.1
ENST00000456466.1
ENST00000319921.4
ring finger protein 213
chr16_-_11876408 0.10 ENST00000396516.2
zinc finger CCCH-type containing 7A
chr6_-_3912207 0.09 ENST00000566733.1
RP1-140K8.5

Network of associatons between targets according to the STRING database.

First level regulatory network of HOXA13

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.2 GO:0017186 peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase(GO:0017186)
0.2 0.6 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.2 0.8 GO:0097045 phosphatidylserine exposure on blood platelet(GO:0097045)
0.2 0.6 GO:0008355 olfactory learning(GO:0008355)
0.1 0.4 GO:0034059 response to anoxia(GO:0034059) positive regulation of penile erection(GO:0060406)
0.1 0.8 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.1 1.0 GO:1900264 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.1 0.8 GO:0061113 pancreas morphogenesis(GO:0061113)
0.1 0.5 GO:0060743 epithelial cell maturation involved in prostate gland development(GO:0060743)
0.1 0.4 GO:0052651 monoacylglycerol metabolic process(GO:0046462) monoacylglycerol catabolic process(GO:0052651)
0.1 0.4 GO:0048691 modulation by virus of host transcription(GO:0019056) positive regulation of sprouting of injured axon(GO:0048687) positive regulation of axon extension involved in regeneration(GO:0048691) modulation by symbiont of host transcription(GO:0052026)
0.1 0.4 GO:0002426 immunoglobulin production in mucosal tissue(GO:0002426)
0.1 0.3 GO:1904479 cellular response to bile acid(GO:1903413) negative regulation of intestinal absorption(GO:1904479) response to iron ion starvation(GO:1990641)
0.1 0.5 GO:2001045 negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.1 0.4 GO:0006421 asparaginyl-tRNA aminoacylation(GO:0006421)
0.1 0.3 GO:0098507 polynucleotide 5' dephosphorylation(GO:0098507)
0.1 0.9 GO:0016554 cytidine to uridine editing(GO:0016554)
0.1 0.3 GO:1990167 protein K27-linked deubiquitination(GO:1990167) protein K33-linked deubiquitination(GO:1990168)
0.1 1.4 GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
0.1 0.4 GO:0090579 transcriptional activation by promoter-enhancer looping(GO:0071733) gene looping(GO:0090202) dsDNA loop formation(GO:0090579)
0.1 0.3 GO:0007206 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
0.1 0.8 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.1 1.1 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.1 0.4 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.1 0.3 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
0.1 0.3 GO:0010157 response to chlorate(GO:0010157)
0.1 0.2 GO:0034473 U1 snRNA 3'-end processing(GO:0034473) U5 snRNA 3'-end processing(GO:0034476)
0.1 0.2 GO:1902824 positive regulation of late endosome to lysosome transport(GO:1902824)
0.1 0.6 GO:0035583 sequestering of TGFbeta in extracellular matrix(GO:0035583)
0.0 0.5 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.0 0.4 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.0 0.1 GO:2000687 negative regulation of rubidium ion transport(GO:2000681) negative regulation of rubidium ion transmembrane transporter activity(GO:2000687)
0.0 0.2 GO:0010652 regulation of cell communication by chemical coupling(GO:0010645) positive regulation of cell communication by chemical coupling(GO:0010652)
0.0 0.4 GO:0045617 negative regulation of keratinocyte differentiation(GO:0045617)
0.0 0.2 GO:0051066 dihydrobiopterin metabolic process(GO:0051066)
0.0 0.4 GO:0003190 atrioventricular valve formation(GO:0003190)
0.0 0.1 GO:0097051 establishment of protein localization to endoplasmic reticulum membrane(GO:0097051)
0.0 0.4 GO:0046498 S-adenosylhomocysteine metabolic process(GO:0046498)
0.0 0.6 GO:0034501 protein localization to kinetochore(GO:0034501)
0.0 2.3 GO:0072698 protein localization to microtubule cytoskeleton(GO:0072698)
0.0 0.2 GO:0097527 necroptotic signaling pathway(GO:0097527)
0.0 0.1 GO:0035720 intraciliary anterograde transport(GO:0035720) ciliary receptor clustering involved in smoothened signaling pathway(GO:0060830)
0.0 0.5 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.0 0.3 GO:0070236 negative regulation of activation-induced cell death of T cells(GO:0070236)
0.0 0.1 GO:0010902 positive regulation of very-low-density lipoprotein particle remodeling(GO:0010902)
0.0 0.2 GO:1902527 positive regulation of protein monoubiquitination(GO:1902527)
0.0 0.2 GO:0097338 response to clozapine(GO:0097338)
0.0 0.2 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
0.0 0.1 GO:0090212 vitamin E metabolic process(GO:0042360) regulation of establishment of blood-brain barrier(GO:0090210) negative regulation of establishment of blood-brain barrier(GO:0090212)
0.0 0.4 GO:0061635 regulation of protein complex stability(GO:0061635)
0.0 0.8 GO:0007099 centriole replication(GO:0007099)
0.0 0.2 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.0 0.4 GO:0001514 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.0 0.2 GO:2000860 positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.0 0.1 GO:2000051 negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
0.0 0.2 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.0 1.1 GO:0043486 histone exchange(GO:0043486)
0.0 0.1 GO:0006433 glutamyl-tRNA aminoacylation(GO:0006424) prolyl-tRNA aminoacylation(GO:0006433)
0.0 0.0 GO:0009826 unidimensional cell growth(GO:0009826)
0.0 0.1 GO:0061534 gamma-aminobutyric acid secretion, neurotransmission(GO:0061534)
0.0 0.2 GO:0048251 elastic fiber assembly(GO:0048251)
0.0 0.3 GO:0051256 mitotic spindle midzone assembly(GO:0051256)
0.0 0.1 GO:0071802 negative regulation of podosome assembly(GO:0071802)
0.0 0.2 GO:0061088 regulation of sequestering of zinc ion(GO:0061088)
0.0 0.1 GO:0006235 dTTP biosynthetic process(GO:0006235) pyrimidine deoxyribonucleoside triphosphate biosynthetic process(GO:0009212)
0.0 0.4 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.0 0.8 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.0 0.2 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.0 0.1 GO:0050882 voluntary musculoskeletal movement(GO:0050882)
0.0 0.5 GO:1903206 negative regulation of hydrogen peroxide-induced cell death(GO:1903206)
0.0 0.2 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.0 0.0 GO:0052314 phytoalexin metabolic process(GO:0052314)
0.0 0.1 GO:0090158 endoplasmic reticulum membrane organization(GO:0090158)
0.0 0.4 GO:0090190 positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190)
0.0 0.2 GO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.0 0.5 GO:0007050 cell cycle arrest(GO:0007050)
0.0 0.2 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.0 0.3 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.0 0.3 GO:1905145 acetylcholine receptor signaling pathway(GO:0095500) postsynaptic signal transduction(GO:0098926) signal transduction involved in cellular response to ammonium ion(GO:1903831) response to acetylcholine(GO:1905144) cellular response to acetylcholine(GO:1905145)
0.0 0.1 GO:0035799 ureter maturation(GO:0035799)
0.0 0.4 GO:0018345 protein palmitoylation(GO:0018345)
0.0 0.2 GO:0007289 spermatid nucleus differentiation(GO:0007289)
0.0 0.1 GO:0061146 Peyer's patch morphogenesis(GO:0061146)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.9 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.1 1.0 GO:0005663 DNA replication factor C complex(GO:0005663)
0.1 1.5 GO:0000812 Swr1 complex(GO:0000812)
0.1 0.4 GO:0044530 supraspliceosomal complex(GO:0044530)
0.1 0.8 GO:0000796 condensin complex(GO:0000796)
0.1 0.3 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.0 0.4 GO:0000801 central element(GO:0000801)
0.0 1.4 GO:0097431 mitotic spindle pole(GO:0097431)
0.0 0.3 GO:0044294 dendritic growth cone(GO:0044294)
0.0 0.6 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 0.2 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.0 0.5 GO:0016600 flotillin complex(GO:0016600)
0.0 0.6 GO:0001527 microfibril(GO:0001527) fibril(GO:0043205)
0.0 0.3 GO:0060091 kinocilium(GO:0060091)
0.0 0.2 GO:0071953 elastic fiber(GO:0071953)
0.0 0.2 GO:0070847 core mediator complex(GO:0070847)
0.0 0.1 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.0 0.1 GO:0071149 TEAD-2-YAP complex(GO:0071149)
0.0 0.6 GO:0051233 spindle midzone(GO:0051233)
0.0 0.2 GO:0000138 Golgi trans cisterna(GO:0000138)
0.0 0.6 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.5 GO:0071011 precatalytic spliceosome(GO:0071011)
0.0 0.3 GO:0045179 apical cortex(GO:0045179)
0.0 0.2 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.0 0.6 GO:0016592 mediator complex(GO:0016592)
0.0 0.4 GO:0044295 axonal growth cone(GO:0044295)
0.0 0.1 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.0 GO:0031592 centrosomal corona(GO:0031592)
0.0 0.4 GO:0000242 pericentriolar material(GO:0000242)
0.0 0.1 GO:0034680 integrin alpha10-beta1 complex(GO:0034680)
0.0 0.2 GO:0005916 fascia adherens(GO:0005916)
0.0 0.1 GO:0030991 intraciliary transport particle A(GO:0030991)
0.0 0.2 GO:0045180 basal cortex(GO:0045180)
0.0 0.1 GO:0005784 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.2 GO:0016603 glutaminyl-peptide cyclotransferase activity(GO:0016603)
0.3 0.9 GO:0016418 S-acetyltransferase activity(GO:0016418)
0.1 0.4 GO:0047225 acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0047225)
0.1 1.0 GO:0033170 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.1 0.6 GO:0050436 microfibril binding(GO:0050436)
0.1 0.3 GO:0000773 phosphatidyl-N-methylethanolamine N-methyltransferase activity(GO:0000773) phosphatidylethanolamine N-methyltransferase activity(GO:0004608) phosphatidyl-N-dimethylethanolamine N-methyltransferase activity(GO:0080101)
0.1 0.3 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.1 0.3 GO:0004651 polynucleotide 5'-phosphatase activity(GO:0004651)
0.1 0.3 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.1 0.8 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.1 0.3 GO:1904455 ubiquitin-specific protease activity involved in negative regulation of ERAD pathway(GO:1904455)
0.1 0.3 GO:0032551 pyrimidine nucleoside binding(GO:0001884) UTP binding(GO:0002134) pyrimidine ribonucleoside binding(GO:0032551)
0.1 0.6 GO:0043515 kinetochore binding(GO:0043515)
0.1 0.4 GO:0004815 aspartate-tRNA ligase activity(GO:0004815)
0.1 0.3 GO:0034603 pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604)
0.1 0.2 GO:0004155 6,7-dihydropteridine reductase activity(GO:0004155)
0.1 0.4 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.0 0.4 GO:0043141 ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.0 0.3 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.0 0.3 GO:0005119 smoothened binding(GO:0005119)
0.0 0.2 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.0 0.7 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.0 0.4 GO:0005000 vasopressin receptor activity(GO:0005000)
0.0 0.7 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 0.2 GO:0043120 tumor necrosis factor binding(GO:0043120)
0.0 0.5 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 0.1 GO:0008431 vitamin E binding(GO:0008431)
0.0 0.4 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.0 0.2 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 0.1 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
0.0 0.4 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.0 0.4 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.2 GO:0047493 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.0 0.2 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.0 0.5 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.0 0.2 GO:0005132 type I interferon receptor binding(GO:0005132)
0.0 1.7 GO:0019894 kinesin binding(GO:0019894)
0.0 0.2 GO:0086075 gap junction channel activity involved in cardiac conduction electrical coupling(GO:0086075)
0.0 0.1 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0 0.1 GO:0016639 oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor(GO:0016639)
0.0 0.1 GO:0004827 glutamate-tRNA ligase activity(GO:0004818) proline-tRNA ligase activity(GO:0004827)
0.0 0.6 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 0.2 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.0 0.1 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.0 0.4 GO:0045295 gamma-catenin binding(GO:0045295)
0.0 0.6 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 1.1 GO:0019212 phosphatase inhibitor activity(GO:0019212)
0.0 0.1 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.0 0.6 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 0.2 GO:0004526 ribonuclease P activity(GO:0004526)
0.0 0.4 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 0.3 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.0 0.2 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.4 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.8 PID AURORA B PATHWAY Aurora B signaling
0.0 0.6 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 1.0 PID FANCONI PATHWAY Fanconi anemia pathway
0.0 0.4 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 0.6 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.4 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.1 1.0 REACTOME POL SWITCHING Genes involved in Polymerase switching
0.0 0.6 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.0 0.5 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.0 0.2 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0 0.4 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
0.0 0.8 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.0 0.4 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.0 0.4 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0 0.4 REACTOME EXTENSION OF TELOMERES Genes involved in Extension of Telomeres
0.0 0.2 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.0 0.4 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 0.4 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 0.6 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.0 0.7 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.4 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.4 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling