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SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for HOXA9

Z-value: 0.79

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Transcription factors associated with HOXA9

Gene Symbol Gene ID Gene Info
HOXA9
ENSG00000078399.11 homeobox A9

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HOXA9hg19_v2_chr7_-_27205136_27205164-0.651.8e-03Click!

Activity profile of HOXA9 motif

Sorted Z-values of HOXA9 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr18_+_61564389 4.34 ENST00000397996.2
ENST00000418725.1
SERPINB10
serpin peptidase inhibitor, clade B (ovalbumin), member 10
chr10_+_51549498 3.33 ENST00000358559.2
ENST00000298239.6
MSMB
microseminoprotein, beta-
chr1_+_209602771 2.90 ENST00000440276.1
MIR205HG
MIR205 host gene (non-protein coding)
chr1_+_24645865 2.58 ENST00000342072.4
GRHL3
grainyhead-like 3 (Drosophila)
chr6_-_56492816 2.50 ENST00000522360.1
DST
dystonin
chr1_+_24645807 2.49 ENST00000361548.4
GRHL3
grainyhead-like 3 (Drosophila)
chr6_+_35310312 2.48 ENST00000448077.2
ENST00000360694.3
ENST00000418635.2
ENST00000444397.1
PPARD
peroxisome proliferator-activated receptor delta
chr8_+_24151553 1.98 ENST00000265769.4
ENST00000540823.1
ENST00000397649.3
ADAM28
ADAM metallopeptidase domain 28
chr20_-_36152914 1.97 ENST00000397131.1
BLCAP
bladder cancer associated protein
chr1_+_152956549 1.94 ENST00000307122.2
SPRR1A
small proline-rich protein 1A
chr7_-_83824449 1.92 ENST00000420047.1
SEMA3A
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr19_-_52598958 1.90 ENST00000594440.1
ENST00000426391.2
ENST00000389534.4
ZNF841
zinc finger protein 841
chr2_+_234104079 1.79 ENST00000417661.1
INPP5D
inositol polyphosphate-5-phosphatase, 145kDa
chr17_-_7493390 1.78 ENST00000538513.2
ENST00000570788.1
ENST00000250055.2
SOX15
SRY (sex determining region Y)-box 15
chr9_+_71820057 1.77 ENST00000539225.1
TJP2
tight junction protein 2
chr12_-_122879969 1.76 ENST00000540304.1
CLIP1
CAP-GLY domain containing linker protein 1
chr18_+_61254221 1.72 ENST00000431153.1
SERPINB13
serpin peptidase inhibitor, clade B (ovalbumin), member 13
chr8_-_37411648 1.67 ENST00000519738.1
RP11-150O12.1
RP11-150O12.1
chr9_+_71819927 1.65 ENST00000535702.1
TJP2
tight junction protein 2
chr5_+_167182003 1.64 ENST00000520394.1
TENM2
teneurin transmembrane protein 2
chr10_+_24544249 1.58 ENST00000430453.2
KIAA1217
KIAA1217
chr1_+_150254936 1.55 ENST00000447007.1
ENST00000369095.1
ENST00000369094.1
C1orf51
chromosome 1 open reading frame 51
chr8_-_42358742 1.53 ENST00000517366.1
SLC20A2
solute carrier family 20 (phosphate transporter), member 2
chr11_-_104905840 1.46 ENST00000526568.1
ENST00000393136.4
ENST00000531166.1
ENST00000534497.1
ENST00000527979.1
ENST00000446369.1
ENST00000353247.5
ENST00000528974.1
ENST00000533400.1
ENST00000525825.1
ENST00000436863.3
CASP1
caspase 1, apoptosis-related cysteine peptidase
chr4_-_102267953 1.44 ENST00000523694.2
ENST00000507176.1
PPP3CA
protein phosphatase 3, catalytic subunit, alpha isozyme
chr3_+_41241596 1.43 ENST00000450969.1
CTNNB1
catenin (cadherin-associated protein), beta 1, 88kDa
chr8_+_24151620 1.43 ENST00000437154.2
ADAM28
ADAM metallopeptidase domain 28
chr1_+_24646002 1.42 ENST00000356046.2
GRHL3
grainyhead-like 3 (Drosophila)
chr6_+_35310391 1.33 ENST00000337400.2
ENST00000311565.4
ENST00000540939.1
PPARD
peroxisome proliferator-activated receptor delta
chr6_+_25279759 1.29 ENST00000377969.3
LRRC16A
leucine rich repeat containing 16A
chr7_-_83824169 1.28 ENST00000265362.4
SEMA3A
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr18_-_68004529 1.28 ENST00000578633.1
RP11-484N16.1
RP11-484N16.1
chr11_-_125351481 1.23 ENST00000577924.1
FEZ1
fasciculation and elongation protein zeta 1 (zygin I)
chr1_-_43919346 1.22 ENST00000372430.3
ENST00000372433.1
ENST00000372434.1
ENST00000486909.1
HYI
hydroxypyruvate isomerase (putative)
chr7_+_55177416 1.22 ENST00000450046.1
ENST00000454757.2
EGFR
epidermal growth factor receptor
chr4_+_154074217 1.20 ENST00000437508.2
TRIM2
tripartite motif containing 2
chr16_-_65106110 1.18 ENST00000562882.1
ENST00000567934.1
CDH11
cadherin 11, type 2, OB-cadherin (osteoblast)
chr1_+_24645915 1.18 ENST00000350501.5
GRHL3
grainyhead-like 3 (Drosophila)
chr2_-_31637560 1.18 ENST00000379416.3
XDH
xanthine dehydrogenase
chr10_+_5488564 1.17 ENST00000449083.1
ENST00000380359.3
NET1
neuroepithelial cell transforming 1
chr16_+_67063855 1.15 ENST00000563939.2
CBFB
core-binding factor, beta subunit
chr4_+_71384300 1.14 ENST00000504451.1
AMTN
amelotin
chr11_+_34664014 1.14 ENST00000527935.1
EHF
ets homologous factor
chr6_+_47666275 1.14 ENST00000327753.3
ENST00000283303.2
GPR115
G protein-coupled receptor 115
chr3_-_196911002 1.13 ENST00000452595.1
DLG1
discs, large homolog 1 (Drosophila)
chr2_+_238600933 1.13 ENST00000420665.1
ENST00000392000.4
LRRFIP1
leucine rich repeat (in FLII) interacting protein 1
chr1_+_24646263 1.12 ENST00000524724.1
GRHL3
grainyhead-like 3 (Drosophila)
chr12_-_54778471 1.12 ENST00000550120.1
ENST00000394313.2
ENST00000547210.1
ZNF385A
zinc finger protein 385A
chr3_+_136649311 1.11 ENST00000469404.1
ENST00000467911.1
NCK1
NCK adaptor protein 1
chr3_-_149510553 1.09 ENST00000462519.2
ENST00000446160.1
ENST00000383050.3
ANKUB1
ankyrin repeat and ubiquitin domain containing 1
chr5_+_149877334 1.07 ENST00000523767.1
NDST1
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
chr12_-_54778444 1.07 ENST00000551771.1
ZNF385A
zinc finger protein 385A
chr4_+_48018781 1.07 ENST00000295461.5
NIPAL1
NIPA-like domain containing 1
chr10_+_24755416 1.04 ENST00000396446.1
ENST00000396445.1
ENST00000376451.2
KIAA1217
KIAA1217
chr1_-_113498616 1.04 ENST00000433570.4
ENST00000538576.1
ENST00000458229.1
SLC16A1
solute carrier family 16 (monocarboxylate transporter), member 1
chr11_+_113185778 1.03 ENST00000524580.2
TTC12
tetratricopeptide repeat domain 12
chr1_+_117963209 1.02 ENST00000449370.2
MAN1A2
mannosidase, alpha, class 1A, member 2
chr3_+_185300391 1.00 ENST00000545472.1
SENP2
SUMO1/sentrin/SMT3 specific peptidase 2
chr3_+_197687071 0.97 ENST00000482695.1
ENST00000330198.4
ENST00000419117.1
ENST00000420910.2
ENST00000332636.5
LMLN
leishmanolysin-like (metallopeptidase M8 family)
chr7_+_20370746 0.97 ENST00000222573.4
ITGB8
integrin, beta 8
chr1_-_24513737 0.96 ENST00000374421.3
ENST00000374418.3
ENST00000327535.1
ENST00000327575.2
IFNLR1
interferon, lambda receptor 1
chr6_+_25279651 0.92 ENST00000329474.6
LRRC16A
leucine rich repeat containing 16A
chr6_+_18155560 0.91 ENST00000546309.2
ENST00000388870.2
ENST00000397244.1
KDM1B
lysine (K)-specific demethylase 1B
chr1_+_230193521 0.91 ENST00000543760.1
GALNT2
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 2 (GalNAc-T2)
chr1_-_43919573 0.90 ENST00000372432.1
ENST00000372425.4
ENST00000583037.1
HYI
hydroxypyruvate isomerase (putative)
chr4_-_186732048 0.89 ENST00000448662.2
ENST00000439049.1
ENST00000420158.1
ENST00000431808.1
ENST00000319471.9
SORBS2
sorbin and SH3 domain containing 2
chr2_-_230787879 0.87 ENST00000435716.1
TRIP12
thyroid hormone receptor interactor 12
chr3_-_48130707 0.85 ENST00000360240.6
ENST00000383737.4
MAP4
microtubule-associated protein 4
chr7_-_27169801 0.85 ENST00000511914.1
HOXA4
homeobox A4
chr10_-_115904361 0.85 ENST00000428953.1
ENST00000543782.1
C10orf118
chromosome 10 open reading frame 118
chr10_+_24738355 0.85 ENST00000307544.6
KIAA1217
KIAA1217
chr6_+_143447322 0.84 ENST00000458219.1
AIG1
androgen-induced 1
chr4_-_99578789 0.82 ENST00000511651.1
ENST00000505184.1
TSPAN5
tetraspanin 5
chr7_+_5468362 0.81 ENST00000608012.1
RP11-1275H24.3
RP11-1275H24.3
chr1_+_12524965 0.81 ENST00000471923.1
VPS13D
vacuolar protein sorting 13 homolog D (S. cerevisiae)
chr4_-_185733394 0.81 ENST00000504342.1
ACSL1
acyl-CoA synthetase long-chain family member 1
chr9_-_27529726 0.80 ENST00000262244.5
MOB3B
MOB kinase activator 3B
chr15_+_94899183 0.80 ENST00000557742.1
MCTP2
multiple C2 domains, transmembrane 2
chr4_+_169633310 0.79 ENST00000510998.1
PALLD
palladin, cytoskeletal associated protein
chr11_-_57092381 0.78 ENST00000358252.3
TNKS1BP1
tankyrase 1 binding protein 1, 182kDa
chr3_-_195310802 0.78 ENST00000421243.1
ENST00000453131.1
APOD
apolipoprotein D
chr5_+_140800638 0.78 ENST00000398587.2
ENST00000518882.1
PCDHGA11
protocadherin gamma subfamily A, 11
chr6_+_108977520 0.74 ENST00000540898.1
FOXO3
forkhead box O3
chr22_-_31324215 0.74 ENST00000429468.1
MORC2
MORC family CW-type zinc finger 2
chr2_+_201170596 0.73 ENST00000439084.1
ENST00000409718.1
SPATS2L
spermatogenesis associated, serine-rich 2-like
chr4_-_159644507 0.73 ENST00000307720.3
PPID
peptidylprolyl isomerase D
chr2_+_74056147 0.72 ENST00000394070.2
ENST00000536064.1
STAMBP
STAM binding protein
chr2_+_74056066 0.71 ENST00000339566.3
ENST00000409707.1
ENST00000452725.1
ENST00000432295.2
ENST00000424659.1
ENST00000394073.1
STAMBP
STAM binding protein
chr18_+_34124507 0.70 ENST00000591635.1
FHOD3
formin homology 2 domain containing 3
chr18_+_21033239 0.70 ENST00000581585.1
ENST00000577501.1
RIOK3
RIO kinase 3
chr4_+_39046615 0.69 ENST00000261425.3
ENST00000508137.2
KLHL5
kelch-like family member 5
chr7_+_69064300 0.69 ENST00000342771.4
AUTS2
autism susceptibility candidate 2
chr4_-_99578776 0.69 ENST00000515287.1
TSPAN5
tetraspanin 5
chr6_+_130339710 0.69 ENST00000526087.1
ENST00000533560.1
ENST00000361794.2
L3MBTL3
l(3)mbt-like 3 (Drosophila)
chr13_+_52586517 0.68 ENST00000523764.1
ENST00000521508.1
ALG11
ALG11, alpha-1,2-mannosyltransferase
chr1_-_23504176 0.68 ENST00000302291.4
LUZP1
leucine zipper protein 1
chr13_-_30881134 0.68 ENST00000380617.3
ENST00000441394.1
KATNAL1
katanin p60 subunit A-like 1
chr17_-_8021710 0.67 ENST00000380149.1
ENST00000448843.2
ALOXE3
arachidonate lipoxygenase 3
chr1_+_101702417 0.67 ENST00000305352.6
S1PR1
sphingosine-1-phosphate receptor 1
chr18_-_12656715 0.67 ENST00000462226.1
ENST00000497844.2
ENST00000309836.5
ENST00000453447.2
SPIRE1
spire-type actin nucleation factor 1
chr11_-_2162162 0.64 ENST00000381389.1
IGF2
insulin-like growth factor 2 (somatomedin A)
chr2_+_138721850 0.63 ENST00000329366.4
ENST00000280097.3
HNMT
histamine N-methyltransferase
chr4_-_83765613 0.62 ENST00000503937.1
SEC31A
SEC31 homolog A (S. cerevisiae)
chr6_+_90272488 0.62 ENST00000485637.1
ENST00000522705.1
ANKRD6
ankyrin repeat domain 6
chr10_-_24911746 0.61 ENST00000320481.6
ARHGAP21
Rho GTPase activating protein 21
chr2_+_182850551 0.61 ENST00000452904.1
ENST00000409137.3
ENST00000280295.3
PPP1R1C
protein phosphatase 1, regulatory (inhibitor) subunit 1C
chr5_-_168006324 0.61 ENST00000522176.1
PANK3
pantothenate kinase 3
chr10_+_47894572 0.60 ENST00000355876.5
FAM21B
family with sequence similarity 21, member B
chr9_+_470288 0.60 ENST00000382303.1
KANK1
KN motif and ankyrin repeat domains 1
chr17_+_61086917 0.60 ENST00000424789.2
ENST00000389520.4
TANC2
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
chr9_+_2029019 0.60 ENST00000382194.1
SMARCA2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr15_-_41166414 0.59 ENST00000220507.4
RHOV
ras homolog family member V
chr4_-_69215467 0.59 ENST00000579690.1
YTHDC1
YTH domain containing 1
chr1_-_152297679 0.58 ENST00000368799.1
FLG
filaggrin
chr10_-_14050522 0.58 ENST00000342409.2
FRMD4A
FERM domain containing 4A
chr3_-_52713729 0.58 ENST00000296302.7
ENST00000356770.4
ENST00000337303.4
ENST00000409057.1
ENST00000410007.1
ENST00000409114.3
ENST00000409767.1
ENST00000423351.1
PBRM1
polybromo 1
chr17_-_39728303 0.56 ENST00000588431.1
ENST00000246662.4
KRT9
keratin 9
chr2_+_64069016 0.56 ENST00000488245.2
UGP2
UDP-glucose pyrophosphorylase 2
chr4_-_110723134 0.55 ENST00000510800.1
ENST00000512148.1
CFI
complement factor I
chr18_+_21032781 0.54 ENST00000339486.3
RIOK3
RIO kinase 3
chr20_+_12989895 0.54 ENST00000450297.1
SPTLC3
serine palmitoyltransferase, long chain base subunit 3
chr4_+_3076388 0.54 ENST00000355072.5
HTT
huntingtin
chr3_+_157827841 0.53 ENST00000295930.3
ENST00000471994.1
ENST00000464171.1
ENST00000312179.6
ENST00000475278.2
RSRC1
arginine/serine-rich coiled-coil 1
chr8_-_101730061 0.53 ENST00000519100.1
PABPC1
poly(A) binding protein, cytoplasmic 1
chr6_-_46138676 0.53 ENST00000371383.2
ENST00000230565.3
ENPP5
ectonucleotide pyrophosphatase/phosphodiesterase 5 (putative)
chr11_+_57529234 0.52 ENST00000360682.6
ENST00000361796.4
ENST00000529526.1
ENST00000426142.2
ENST00000399050.4
ENST00000361391.6
ENST00000361332.4
ENST00000532463.1
ENST00000529986.1
ENST00000358694.6
ENST00000532787.1
ENST00000533667.1
ENST00000532649.1
ENST00000528621.1
ENST00000530748.1
ENST00000428599.2
ENST00000527467.1
ENST00000528232.1
ENST00000531014.1
ENST00000526772.1
ENST00000529873.1
ENST00000525902.1
ENST00000532844.1
ENST00000526357.1
ENST00000530094.1
ENST00000415361.2
ENST00000532245.1
ENST00000534579.1
ENST00000526938.1
CTNND1
catenin (cadherin-associated protein), delta 1
chr2_-_122262593 0.52 ENST00000418989.1
CLASP1
cytoplasmic linker associated protein 1
chr5_-_150138061 0.52 ENST00000521533.1
ENST00000424236.1
DCTN4
dynactin 4 (p62)
chr12_+_27398584 0.52 ENST00000543246.1
STK38L
serine/threonine kinase 38 like
chr20_+_19870167 0.51 ENST00000440354.2
RIN2
Ras and Rab interactor 2
chr4_-_74088800 0.51 ENST00000509867.2
ANKRD17
ankyrin repeat domain 17
chr15_+_45315302 0.50 ENST00000267814.9
SORD
sorbitol dehydrogenase
chr13_-_30880979 0.49 ENST00000414289.1
KATNAL1
katanin p60 subunit A-like 1
chr4_-_48018680 0.49 ENST00000513178.1
CNGA1
cyclic nucleotide gated channel alpha 1
chr17_-_12920907 0.49 ENST00000609757.1
ENST00000581499.2
ENST00000580504.1
ELAC2
elaC ribonuclease Z 2
chr18_+_56532100 0.49 ENST00000588456.1
ENST00000589481.1
ENST00000591049.1
ZNF532
zinc finger protein 532
chr4_-_69434245 0.48 ENST00000317746.2
UGT2B17
UDP glucuronosyltransferase 2 family, polypeptide B17
chr10_+_85933494 0.48 ENST00000372126.3
C10orf99
chromosome 10 open reading frame 99
chr2_+_149894968 0.48 ENST00000409642.3
LYPD6B
LY6/PLAUR domain containing 6B
chr3_+_57875738 0.48 ENST00000417128.1
ENST00000438794.1
SLMAP
sarcolemma associated protein
chr8_+_69242957 0.48 ENST00000518698.1
ENST00000539993.1
C8orf34
chromosome 8 open reading frame 34
chr7_+_65338312 0.47 ENST00000434382.2
VKORC1L1
vitamin K epoxide reductase complex, subunit 1-like 1
chr1_-_22109484 0.47 ENST00000529637.1
USP48
ubiquitin specific peptidase 48
chr11_+_118938485 0.47 ENST00000300793.6
VPS11
vacuolar protein sorting 11 homolog (S. cerevisiae)
chr1_+_52082751 0.46 ENST00000447887.1
ENST00000435686.2
ENST00000428468.1
ENST00000453295.1
OSBPL9
oxysterol binding protein-like 9
chr15_-_49338748 0.46 ENST00000559471.1
SECISBP2L
SECIS binding protein 2-like
chr5_-_180288248 0.45 ENST00000512132.1
ENST00000506439.1
ENST00000502412.1
ENST00000359141.6
ZFP62
ZFP62 zinc finger protein
chr20_+_58203664 0.44 ENST00000541461.1
PHACTR3
phosphatase and actin regulator 3
chr20_-_48732472 0.44 ENST00000340309.3
ENST00000415862.2
ENST00000371677.3
ENST00000420027.2
UBE2V1
ubiquitin-conjugating enzyme E2 variant 1
chr18_+_11857439 0.44 ENST00000602628.1
GNAL
guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type
chr16_-_89556942 0.44 ENST00000301030.4
ANKRD11
ankyrin repeat domain 11
chr13_+_98794810 0.44 ENST00000595437.1
FARP1
FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)
chr1_-_28969517 0.43 ENST00000263974.4
ENST00000373824.4
TAF12
TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 20kDa
chr6_+_158733692 0.43 ENST00000367094.2
ENST00000367097.3
TULP4
tubby like protein 4
chr18_+_42260861 0.42 ENST00000282030.5
SETBP1
SET binding protein 1
chr18_+_72265084 0.42 ENST00000582337.1
ZNF407
zinc finger protein 407
chr4_-_72649763 0.41 ENST00000513476.1
GC
group-specific component (vitamin D binding protein)
chr17_-_48943706 0.41 ENST00000499247.2
TOB1
transducer of ERBB2, 1
chr17_+_7758374 0.41 ENST00000301599.6
ENST00000574668.1
TMEM88
transmembrane protein 88
chr4_-_48018580 0.40 ENST00000514170.1
CNGA1
cyclic nucleotide gated channel alpha 1
chr11_+_57435441 0.40 ENST00000528177.1
ZDHHC5
zinc finger, DHHC-type containing 5
chr8_-_97247759 0.40 ENST00000518406.1
ENST00000523920.1
ENST00000287022.5
UQCRB
ubiquinol-cytochrome c reductase binding protein
chr10_+_90484301 0.40 ENST00000404190.1
LIPK
lipase, family member K
chr6_+_125304502 0.39 ENST00000519799.1
ENST00000368414.2
ENST00000359704.2
RNF217
ring finger protein 217
chr14_-_90085458 0.39 ENST00000345097.4
ENST00000555855.1
ENST00000555353.1
FOXN3
forkhead box N3
chr12_+_25205666 0.38 ENST00000547044.1
LRMP
lymphoid-restricted membrane protein
chr2_-_197675000 0.38 ENST00000342506.2
C2orf66
chromosome 2 open reading frame 66
chr2_+_219646462 0.38 ENST00000258415.4
CYP27A1
cytochrome P450, family 27, subfamily A, polypeptide 1
chr11_+_27062272 0.38 ENST00000529202.1
ENST00000533566.1
BBOX1
butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
chr10_+_51572339 0.38 ENST00000344348.6
NCOA4
nuclear receptor coactivator 4
chr19_+_4769117 0.37 ENST00000540211.1
ENST00000317292.3
ENST00000586721.1
ENST00000592709.1
ENST00000588711.1
ENST00000589639.1
ENST00000591008.1
ENST00000592663.1
ENST00000588758.1
MIR7-3HG
MIR7-3 host gene (non-protein coding)
chr12_+_25205568 0.37 ENST00000548766.1
ENST00000556887.1
LRMP
lymphoid-restricted membrane protein
chr1_-_33502441 0.37 ENST00000548033.1
ENST00000487289.1
ENST00000373449.2
ENST00000480134.1
ENST00000467905.1
AK2
adenylate kinase 2
chr4_+_26344754 0.37 ENST00000515573.1
RBPJ
recombination signal binding protein for immunoglobulin kappa J region
chr3_-_197686847 0.37 ENST00000265239.6
IQCG
IQ motif containing G
chr4_-_100356291 0.37 ENST00000476959.1
ENST00000482593.1
ADH7
alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
chr1_+_198189921 0.36 ENST00000391974.3
NEK7
NIMA-related kinase 7
chr3_+_177545563 0.36 ENST00000434309.1
RP11-91K9.1
RP11-91K9.1
chr11_+_59522837 0.36 ENST00000437946.2
STX3
syntaxin 3
chr5_-_131347501 0.35 ENST00000543479.1
ACSL6
acyl-CoA synthetase long-chain family member 6
chr12_+_32687221 0.35 ENST00000525053.1
FGD4
FYVE, RhoGEF and PH domain containing 4
chr2_+_64069240 0.35 ENST00000497883.1
UGP2
UDP-glucose pyrophosphorylase 2
chr1_+_38512799 0.35 ENST00000432922.1
ENST00000428151.1
RP5-884C9.2
RP5-884C9.2
chr11_-_104893863 0.35 ENST00000260315.3
ENST00000526056.1
ENST00000531367.1
ENST00000456094.1
ENST00000444749.2
ENST00000393141.2
ENST00000418434.1
ENST00000393139.2
CASP5
caspase 5, apoptosis-related cysteine peptidase
chrX_-_107682702 0.35 ENST00000372216.4
COL4A6
collagen, type IV, alpha 6
chr19_-_18314836 0.35 ENST00000464076.3
ENST00000222256.4
RAB3A
RAB3A, member RAS oncogene family
chr2_-_214017151 0.35 ENST00000452786.1
IKZF2
IKAROS family zinc finger 2 (Helios)
chr3_+_57875711 0.34 ENST00000442599.2
SLMAP
sarcolemma associated protein
chr1_-_22109682 0.34 ENST00000400301.1
ENST00000532737.1
USP48
ubiquitin specific peptidase 48
chr19_+_44645700 0.34 ENST00000592437.1
ZNF234
zinc finger protein 234
chr13_-_30881621 0.34 ENST00000380615.3
KATNAL1
katanin p60 subunit A-like 1
chr1_-_220263096 0.33 ENST00000463953.1
ENST00000354807.3
ENST00000414869.2
ENST00000498237.2
ENST00000498791.2
ENST00000544404.1
ENST00000480959.2
ENST00000322067.7
BPNT1
3'(2'), 5'-bisphosphate nucleotidase 1
chr11_-_108464465 0.33 ENST00000525344.1
EXPH5
exophilin 5
chrX_-_130037162 0.32 ENST00000432489.1
ENOX2
ecto-NOX disulfide-thiol exchanger 2
chr3_-_143567262 0.31 ENST00000474151.1
ENST00000316549.6
SLC9A9
solute carrier family 9, subfamily A (NHE9, cation proton antiporter 9), member 9
chr3_+_577893 0.31 ENST00000420823.1
ENST00000442809.1
AC090044.1
AC090044.1
chr5_+_38845960 0.31 ENST00000502536.1
OSMR
oncostatin M receptor
chr1_-_144866711 0.31 ENST00000530130.1
PDE4DIP
phosphodiesterase 4D interacting protein
chr6_+_71104588 0.30 ENST00000418403.1
RP11-462G2.1
RP11-462G2.1
chr10_-_96829246 0.30 ENST00000371270.3
ENST00000535898.1
ENST00000539050.1
CYP2C8
cytochrome P450, family 2, subfamily C, polypeptide 8

Network of associatons between targets according to the STRING database.

First level regulatory network of HOXA9

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 3.2 GO:1903045 neural crest cell migration involved in sympathetic nervous system development(GO:1903045)
0.6 1.8 GO:0048627 myoblast development(GO:0048627)
0.6 1.7 GO:1902173 negative regulation of keratinocyte apoptotic process(GO:1902173)
0.4 3.8 GO:0043415 positive regulation of skeletal muscle tissue regeneration(GO:0043415)
0.4 1.1 GO:0070175 positive regulation of enamel mineralization(GO:0070175)
0.4 1.1 GO:1903674 regulation of cap-dependent translational initiation(GO:1903674) positive regulation of cap-dependent translational initiation(GO:1903676)
0.4 8.8 GO:0090179 planar cell polarity pathway involved in neural tube closure(GO:0090179)
0.4 1.5 GO:0050717 positive regulation of interleukin-1 alpha secretion(GO:0050717)
0.4 1.4 GO:1905205 positive regulation of connective tissue replacement(GO:1905205)
0.4 1.4 GO:1904501 glial cell fate determination(GO:0007403) canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation(GO:0061324) regulation of chromatin-mediated maintenance of transcription(GO:1904499) positive regulation of chromatin-mediated maintenance of transcription(GO:1904501) regulation of euchromatin binding(GO:1904793)
0.4 1.8 GO:0045658 regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
0.3 1.0 GO:0015728 mevalonate transport(GO:0015728) behavioral response to nutrient(GO:0051780)
0.3 3.4 GO:0071847 TNFSF11-mediated signaling pathway(GO:0071847)
0.3 2.2 GO:0010609 mRNA localization resulting in posttranscriptional regulation of gene expression(GO:0010609) regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902162) positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902164)
0.3 1.2 GO:0043006 activation of phospholipase A2 activity by calcium-mediated signaling(GO:0043006)
0.3 1.2 GO:0046110 xanthine metabolic process(GO:0046110)
0.3 0.5 GO:0031587 positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0031587)
0.3 1.8 GO:0044861 protein transport into plasma membrane raft(GO:0044861)
0.2 1.2 GO:0039534 negative regulation of MDA-5 signaling pathway(GO:0039534)
0.2 0.7 GO:0001544 initiation of primordial ovarian follicle growth(GO:0001544)
0.2 0.7 GO:0021503 neural fold bending(GO:0021503)
0.2 0.7 GO:0003245 cardiac muscle tissue growth involved in heart morphogenesis(GO:0003245)
0.2 0.6 GO:2000393 negative regulation of lamellipodium morphogenesis(GO:2000393)
0.2 0.8 GO:2000097 regulation of smooth muscle cell-matrix adhesion(GO:2000097)
0.2 0.5 GO:0006059 hexitol metabolic process(GO:0006059)
0.2 0.5 GO:0072684 mitochondrial tRNA 3'-trailer cleavage, endonucleolytic(GO:0072684)
0.2 0.9 GO:0002378 immunoglobulin biosynthetic process(GO:0002378)
0.2 1.5 GO:0051013 microtubule severing(GO:0051013)
0.1 1.0 GO:1904381 Golgi apparatus mannose trimming(GO:1904381)
0.1 2.1 GO:0008090 retrograde axonal transport(GO:0008090)
0.1 0.5 GO:0039533 regulation of MDA-5 signaling pathway(GO:0039533) positive regulation of MDA-5 signaling pathway(GO:1900245)
0.1 0.9 GO:0051012 microtubule sliding(GO:0051012)
0.1 1.1 GO:0019255 glucose 1-phosphate metabolic process(GO:0019255)
0.1 0.3 GO:1990709 maintenance of synapse structure(GO:0099558) presynaptic active zone organization(GO:1990709)
0.1 1.1 GO:1903764 regulation of potassium ion export across plasma membrane(GO:1903764)
0.1 0.8 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.1 1.6 GO:0097264 self proteolysis(GO:0097264)
0.1 1.3 GO:0006477 protein sulfation(GO:0006477)
0.1 0.4 GO:0010430 fatty acid omega-oxidation(GO:0010430)
0.1 0.6 GO:0051684 maintenance of Golgi location(GO:0051684)
0.1 0.9 GO:0033183 negative regulation of histone ubiquitination(GO:0033183) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315)
0.1 0.5 GO:0001692 histamine metabolic process(GO:0001692)
0.1 0.3 GO:1904017 cellular response to Thyroglobulin triiodothyronine(GO:1904017)
0.1 0.7 GO:0051122 hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.1 1.4 GO:0014067 negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067)
0.1 0.7 GO:0040038 polar body extrusion after meiotic divisions(GO:0040038) formin-nucleated actin cable assembly(GO:0070649)
0.1 1.0 GO:0035562 negative regulation of chromatin binding(GO:0035562)
0.1 1.2 GO:1902902 negative regulation of autophagosome assembly(GO:1902902)
0.1 0.2 GO:0021912 regulation of transcription from RNA polymerase II promoter involved in spinal cord motor neuron fate specification(GO:0021912)
0.1 0.9 GO:0034720 histone H3-K4 demethylation(GO:0034720)
0.1 0.4 GO:0006172 ADP biosynthetic process(GO:0006172)
0.1 0.7 GO:0071492 cellular response to UV-A(GO:0071492)
0.1 1.2 GO:0051451 myoblast migration(GO:0051451)
0.1 0.8 GO:0034201 response to oleic acid(GO:0034201)
0.1 1.0 GO:0015693 magnesium ion transport(GO:0015693)
0.1 0.3 GO:0038018 Wnt receptor catabolic process(GO:0038018)
0.1 1.2 GO:0021957 corticospinal tract morphogenesis(GO:0021957)
0.1 0.6 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028) positive regulation of glycogen (starch) synthase activity(GO:2000467)
0.1 1.0 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.1 0.2 GO:0033861 negative regulation of NAD(P)H oxidase activity(GO:0033861)
0.1 0.7 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.1 1.4 GO:0003334 keratinocyte development(GO:0003334)
0.1 0.2 GO:0033685 negative regulation of luteinizing hormone secretion(GO:0033685)
0.0 0.2 GO:0006566 threonine metabolic process(GO:0006566)
0.0 0.4 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.0 0.4 GO:1901189 positive regulation of ephrin receptor signaling pathway(GO:1901189) positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068)
0.0 0.3 GO:1901525 negative regulation of macromitophagy(GO:1901525)
0.0 0.9 GO:1902373 negative regulation of mRNA catabolic process(GO:1902373)
0.0 0.7 GO:0043249 erythrocyte maturation(GO:0043249)
0.0 0.4 GO:0007288 sperm axoneme assembly(GO:0007288)
0.0 0.4 GO:0017062 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.0 0.5 GO:0042373 vitamin K metabolic process(GO:0042373)
0.0 0.4 GO:0070269 ectopic germ cell programmed cell death(GO:0035234) pyroptosis(GO:0070269)
0.0 0.2 GO:0043605 cellular amide catabolic process(GO:0043605)
0.0 2.0 GO:0030262 apoptotic nuclear changes(GO:0030262)
0.0 0.4 GO:0098881 exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967)
0.0 0.7 GO:0007097 nuclear migration(GO:0007097)
0.0 0.6 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.0 0.2 GO:0002018 renin-angiotensin regulation of aldosterone production(GO:0002018)
0.0 0.3 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.0 0.2 GO:0045229 cell envelope organization(GO:0043163) external encapsulating structure organization(GO:0045229)
0.0 0.5 GO:0090091 positive regulation of extracellular matrix disassembly(GO:0090091) negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.0 0.5 GO:0034058 endosomal vesicle fusion(GO:0034058) positive regulation of early endosome to late endosome transport(GO:2000643)
0.0 1.2 GO:0045589 regulation of regulatory T cell differentiation(GO:0045589)
0.0 2.1 GO:0018149 peptide cross-linking(GO:0018149)
0.0 1.5 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
0.0 1.0 GO:0002385 mucosal immune response(GO:0002385)
0.0 0.1 GO:2000078 glandular epithelial cell maturation(GO:0002071) type B pancreatic cell maturation(GO:0072560) positive regulation of type B pancreatic cell development(GO:2000078)
0.0 0.5 GO:0001514 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.0 0.6 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 0.2 GO:0044026 DNA hypermethylation(GO:0044026)
0.0 0.4 GO:1904355 regulation of telomere capping(GO:1904353) positive regulation of telomere capping(GO:1904355)
0.0 0.5 GO:0046520 sphingoid biosynthetic process(GO:0046520)
0.0 1.0 GO:0001573 ganglioside metabolic process(GO:0001573)
0.0 0.2 GO:0055011 atrial cardiac muscle cell differentiation(GO:0055011) atrial cardiac muscle cell development(GO:0055014)
0.0 0.2 GO:0010819 regulation of T cell chemotaxis(GO:0010819)
0.0 0.7 GO:0006490 oligosaccharide-lipid intermediate biosynthetic process(GO:0006490)
0.0 0.2 GO:1904550 chemotaxis to arachidonic acid(GO:0034670) response to arachidonic acid(GO:1904550)
0.0 0.7 GO:0051639 actin filament network formation(GO:0051639)
0.0 0.1 GO:2000768 glomerular parietal epithelial cell differentiation(GO:0072139) positive regulation of epithelial cell differentiation involved in kidney development(GO:2000698) positive regulation of nephron tubule epithelial cell differentiation(GO:2000768)
0.0 0.3 GO:0070779 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.0 0.1 GO:0018032 protein amidation(GO:0018032)
0.0 0.6 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.0 0.3 GO:0090204 protein localization to nuclear pore(GO:0090204)
0.0 0.6 GO:0045109 intermediate filament organization(GO:0045109)
0.0 0.2 GO:0038165 oncostatin-M-mediated signaling pathway(GO:0038165)
0.0 0.2 GO:0002326 B cell lineage commitment(GO:0002326) immunoglobulin V(D)J recombination(GO:0033152)
0.0 0.5 GO:0098719 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 0.3 GO:2000400 positive regulation of T cell differentiation in thymus(GO:0033089) positive regulation of thymocyte aggregation(GO:2000400)
0.0 0.1 GO:0070343 white fat cell proliferation(GO:0070343) regulation of white fat cell proliferation(GO:0070350)
0.0 0.2 GO:1902177 positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway(GO:1902177)
0.0 0.3 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.0 0.1 GO:0016480 negative regulation of transcription from RNA polymerase III promoter(GO:0016480)
0.0 0.4 GO:0097094 craniofacial suture morphogenesis(GO:0097094)
0.0 0.1 GO:1901475 pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475)
0.0 0.1 GO:0009236 cobalamin biosynthetic process(GO:0009236)
0.0 0.7 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.0 0.0 GO:2000296 negative regulation of hydrogen peroxide catabolic process(GO:2000296)
0.0 0.1 GO:0006642 triglyceride mobilization(GO:0006642)
0.0 0.6 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.0 0.7 GO:0006622 protein targeting to lysosome(GO:0006622)
0.0 0.5 GO:0035635 entry of bacterium into host cell(GO:0035635)
0.0 0.3 GO:0007191 adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
0.0 0.5 GO:0010800 positive regulation of peptidyl-threonine phosphorylation(GO:0010800)
0.0 0.1 GO:1902527 positive regulation of protein monoubiquitination(GO:1902527)
0.0 0.1 GO:0071231 thymidylate synthase biosynthetic process(GO:0050757) regulation of thymidylate synthase biosynthetic process(GO:0050758) cellular response to folic acid(GO:0071231)
0.0 0.8 GO:0006699 bile acid biosynthetic process(GO:0006699)
0.0 0.5 GO:0050832 defense response to fungus(GO:0050832)
0.0 0.1 GO:0048341 paraxial mesoderm formation(GO:0048341)
0.0 0.2 GO:0045103 intermediate filament-based process(GO:0045103)
0.0 0.4 GO:0060325 face morphogenesis(GO:0060325)
0.0 0.1 GO:0030916 otic vesicle formation(GO:0030916) otic vesicle morphogenesis(GO:0071600)
0.0 0.2 GO:0034356 NAD biosynthesis via nicotinamide riboside salvage pathway(GO:0034356)
0.0 0.3 GO:0052695 cellular glucuronidation(GO:0052695)
0.0 0.5 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0 0.4 GO:0042359 vitamin D metabolic process(GO:0042359)
0.0 0.1 GO:0042427 serotonin biosynthetic process(GO:0042427)
0.0 1.9 GO:0048706 embryonic skeletal system development(GO:0048706)
0.0 0.5 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.5 GO:0031673 H zone(GO:0031673)
0.4 1.2 GO:0097489 multivesicular body, internal vesicle lumen(GO:0097489)
0.3 1.0 GO:0034686 integrin alphav-beta8 complex(GO:0034686)
0.3 1.0 GO:0032002 interleukin-28 receptor complex(GO:0032002)
0.3 0.8 GO:0036457 keratohyalin granule(GO:0036457)
0.3 1.8 GO:0072558 NLRP1 inflammasome complex(GO:0072558)
0.2 1.4 GO:0070369 Scrib-APC-beta-catenin complex(GO:0034750) beta-catenin-TCF7L2 complex(GO:0070369)
0.2 1.8 GO:0044354 pinosome(GO:0044352) macropinosome(GO:0044354)
0.1 1.4 GO:0005955 calcineurin complex(GO:0005955)
0.1 0.5 GO:0031592 centrosomal corona(GO:0031592)
0.1 1.2 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.1 0.4 GO:1990796 photoreceptor cell terminal bouton(GO:1990796)
0.1 0.4 GO:0035370 UBC13-UEV1A complex(GO:0035370)
0.1 1.1 GO:0097025 lateral loop(GO:0043219) MPP7-DLG1-LIN7 complex(GO:0097025)
0.1 0.2 GO:0005900 oncostatin-M receptor complex(GO:0005900)
0.1 1.1 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 0.4 GO:0002177 manchette(GO:0002177)
0.0 0.3 GO:0032589 axolemma(GO:0030673) neuron projection membrane(GO:0032589)
0.0 1.0 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 0.5 GO:0031211 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0 0.7 GO:0044754 autolysosome(GO:0044754)
0.0 0.3 GO:0005587 collagen type IV trimer(GO:0005587)
0.0 0.3 GO:0060201 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.0 1.2 GO:0030014 CCR4-NOT complex(GO:0030014)
0.0 0.4 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0 4.0 GO:0101003 ficolin-1-rich granule membrane(GO:0101003)
0.0 2.3 GO:0001533 cornified envelope(GO:0001533)
0.0 0.4 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0 0.7 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.2 GO:0035032 phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.0 1.1 GO:0005605 basal lamina(GO:0005605)
0.0 0.5 GO:0005915 zonula adherens(GO:0005915)
0.0 1.2 GO:0090544 BAF-type complex(GO:0090544)
0.0 0.5 GO:0008091 spectrin(GO:0008091)
0.0 0.4 GO:0000124 SAGA complex(GO:0000124) STAGA complex(GO:0030914)
0.0 0.5 GO:0030897 HOPS complex(GO:0030897)
0.0 0.2 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
0.0 0.5 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 4.1 GO:0005923 bicellular tight junction(GO:0005923)
0.0 0.3 GO:0005869 dynactin complex(GO:0005869)
0.0 2.6 GO:0016605 PML body(GO:0016605)
0.0 0.4 GO:0000786 nucleosome(GO:0000786)
0.0 0.8 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.0 0.0 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.0 1.4 GO:0030425 dendrite(GO:0030425)
0.0 1.1 GO:0035577 azurophil granule membrane(GO:0035577)
0.0 0.9 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 5.6 GO:0000790 nuclear chromatin(GO:0000790)
0.0 2.6 GO:0042579 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 0.6 GO:0005865 striated muscle thin filament(GO:0005865)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0015130 mevalonate transmembrane transporter activity(GO:0015130)
0.3 1.0 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.2 1.2 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.2 1.8 GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.2 1.1 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
0.2 2.4 GO:0030280 structural constituent of epidermis(GO:0030280)
0.2 1.3 GO:0050119 N-acetylglucosamine deacetylase activity(GO:0050119)
0.2 0.7 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.2 0.7 GO:0000026 alpha-1,2-mannosyltransferase activity(GO:0000026)
0.2 1.5 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.2 1.1 GO:0051748 UTP:glucose-1-phosphate uridylyltransferase activity(GO:0003983) UTP-monosaccharide-1-phosphate uridylyltransferase activity(GO:0051748)
0.1 3.2 GO:0030215 semaphorin receptor binding(GO:0030215)
0.1 4.2 GO:0036041 long-chain fatty acid binding(GO:0036041)
0.1 0.4 GO:1902271 D3 vitamins binding(GO:1902271)
0.1 1.5 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.1 2.2 GO:0016018 cyclosporin A binding(GO:0016018)
0.1 0.7 GO:0051120 hepoxilin A3 synthase activity(GO:0051120)
0.1 2.1 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.1 1.2 GO:0043546 molybdopterin cofactor binding(GO:0043546)
0.1 1.0 GO:0070137 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.1 0.4 GO:0004031 aldehyde oxidase activity(GO:0004031)
0.1 0.5 GO:0042781 3'-tRNA processing endoribonuclease activity(GO:0042781)
0.1 0.9 GO:0034648 histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.1 0.3 GO:0008441 3'(2'),5'-bisphosphate nucleotidase activity(GO:0008441)
0.1 0.3 GO:0005128 erythropoietin receptor binding(GO:0005128)
0.1 4.8 GO:0051010 microtubule plus-end binding(GO:0051010)
0.1 0.5 GO:0047057 oxidoreductase activity, acting on the CH-OH group of donors, disulfide as acceptor(GO:0016900) vitamin-K-epoxide reductase (warfarin-sensitive) activity(GO:0047057)
0.1 1.2 GO:0089720 caspase binding(GO:0089720)
0.1 1.1 GO:0097016 L27 domain binding(GO:0097016)
0.1 0.6 GO:0004594 pantothenate kinase activity(GO:0004594)
0.1 1.5 GO:0050700 CARD domain binding(GO:0050700)
0.1 0.2 GO:0047280 nicotinamide phosphoribosyltransferase activity(GO:0047280)
0.1 0.2 GO:0070644 vitamin D response element binding(GO:0070644)
0.1 0.4 GO:0003875 ADP-ribosylarginine hydrolase activity(GO:0003875)
0.1 3.4 GO:0004385 guanylate kinase activity(GO:0004385)
0.1 0.8 GO:0071532 ankyrin repeat binding(GO:0071532)
0.1 1.0 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.1 0.5 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.1 0.5 GO:0035368 selenocysteine insertion sequence binding(GO:0035368)
0.1 0.3 GO:0010861 thyroid hormone receptor activator activity(GO:0010861) thyroid hormone receptor coactivator activity(GO:0030375)
0.1 0.9 GO:0005221 intracellular cyclic nucleotide activated cation channel activity(GO:0005221) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.1 9.4 GO:0031490 chromatin DNA binding(GO:0031490)
0.1 1.4 GO:0045294 alpha-catenin binding(GO:0045294)
0.1 0.2 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.1 1.5 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.1 0.2 GO:0004995 tachykinin receptor activity(GO:0004995)
0.1 0.7 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.1 0.4 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0 0.6 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.0 0.3 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.0 0.6 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0 0.2 GO:0004906 interferon-gamma receptor activity(GO:0004906)
0.0 0.5 GO:0042731 PH domain binding(GO:0042731)
0.0 0.1 GO:0005477 pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.0 5.0 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.9 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.5 GO:0034452 dynactin binding(GO:0034452)
0.0 0.5 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.0 0.2 GO:0004924 oncostatin-M receptor activity(GO:0004924)
0.0 0.3 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.0 0.2 GO:0016453 C-acetyltransferase activity(GO:0016453)
0.0 0.1 GO:0051011 microtubule minus-end binding(GO:0051011)
0.0 4.3 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 1.2 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 0.3 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.0 0.6 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.4 GO:0015035 protein disulfide oxidoreductase activity(GO:0015035)
0.0 0.5 GO:0008494 translation activator activity(GO:0008494)
0.0 0.1 GO:0004598 peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598)
0.0 0.9 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.4 GO:0000150 recombinase activity(GO:0000150)
0.0 0.7 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 0.2 GO:1990763 arrestin family protein binding(GO:1990763)
0.0 2.5 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 0.4 GO:0004017 adenylate kinase activity(GO:0004017)
0.0 0.1 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.0 0.3 GO:0030548 acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.0 0.9 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.0 0.1 GO:0004510 tryptophan 5-monooxygenase activity(GO:0004510)
0.0 0.1 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.0 0.8 GO:0015485 cholesterol binding(GO:0015485)
0.0 0.1 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.0 0.4 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.0 1.8 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.0 0.1 GO:0061714 folic acid receptor activity(GO:0061714)
0.0 0.5 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.4 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.5 GO:0001972 retinoic acid binding(GO:0001972)
0.0 0.1 GO:0001016 RNA polymerase III regulatory region DNA binding(GO:0001016) thioredoxin peroxidase activity(GO:0008379)
0.0 0.9 GO:0050681 androgen receptor binding(GO:0050681)
0.0 0.4 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.4 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.8 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 3.2 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 3.9 PID INSULIN PATHWAY Insulin Pathway
0.0 3.4 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.0 1.1 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 1.0 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 1.4 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 1.6 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 1.1 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 1.4 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 0.3 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 2.5 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.3 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.0 3.5 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 1.1 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 1.4 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.0 0.2 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.0 0.4 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 0.4 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.0 0.4 PID MYC PATHWAY C-MYC pathway
0.0 4.9 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 1.0 PID ATF2 PATHWAY ATF-2 transcription factor network
0.0 1.9 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.0 1.3 PID CMYB PATHWAY C-MYB transcription factor network
0.0 0.7 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 4.8 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.1 3.2 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.1 1.5 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.1 1.2 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.1 1.2 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 1.1 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 1.5 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 1.1 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 1.1 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 1.0 REACTOME SHC1 EVENTS IN EGFR SIGNALING Genes involved in SHC1 events in EGFR signaling
0.0 1.8 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.2 REACTOME SHC RELATED EVENTS Genes involved in SHC-related events
0.0 0.6 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 1.3 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.4 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0 1.3 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 0.2 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.0 0.6 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 1.4 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.7 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.0 2.4 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.4 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.0 0.7 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0 1.6 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.0 0.7 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 0.4 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.0 0.3 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0 0.4 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 1.7 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 0.4 REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Dopamine Neurotransmitter Release Cycle
0.0 0.4 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 0.5 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor