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SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for HOXB3

Z-value: 1.60

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Transcription factors associated with HOXB3

Gene Symbol Gene ID Gene Info
HOXB3
ENSG00000120093.7 homeobox B3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HOXB3hg19_v2_chr17_-_46667628_46667642-0.843.8e-06Click!

Activity profile of HOXB3 motif

Sorted Z-values of HOXB3 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr12_-_123187890 8.56 ENST00000328880.5
HCAR2
hydroxycarboxylic acid receptor 2
chr1_+_209602156 8.35 ENST00000429156.1
ENST00000366437.3
ENST00000603283.1
ENST00000431096.1
MIR205HG
MIR205 host gene (non-protein coding)
chr8_-_49834299 7.98 ENST00000396822.1
SNAI2
snail family zinc finger 2
chr8_-_49833978 7.93 ENST00000020945.1
SNAI2
snail family zinc finger 2
chr3_+_195447738 7.62 ENST00000447234.2
ENST00000320736.6
ENST00000436408.1
MUC20
mucin 20, cell surface associated
chr12_-_123201337 7.37 ENST00000528880.2
HCAR3
hydroxycarboxylic acid receptor 3
chr3_-_151034734 6.52 ENST00000260843.4
GPR87
G protein-coupled receptor 87
chr1_+_156030937 6.03 ENST00000361084.5
RAB25
RAB25, member RAS oncogene family
chr18_+_61554932 5.84 ENST00000299502.4
ENST00000457692.1
ENST00000413956.1
SERPINB2
serpin peptidase inhibitor, clade B (ovalbumin), member 2
chr9_+_130911723 5.78 ENST00000277480.2
ENST00000373013.2
ENST00000540948.1
LCN2
lipocalin 2
chr9_+_130911770 5.57 ENST00000372998.1
LCN2
lipocalin 2
chr18_+_61557781 5.26 ENST00000443281.1
SERPINB2
serpin peptidase inhibitor, clade B (ovalbumin), member 2
chr11_+_5710919 5.10 ENST00000379965.3
ENST00000425490.1
TRIM22
tripartite motif containing 22
chr11_-_118134997 5.01 ENST00000278937.2
MPZL2
myelin protein zero-like 2
chr11_-_118135160 4.88 ENST00000438295.2
MPZL2
myelin protein zero-like 2
chr19_+_11071546 4.59 ENST00000358026.2
SMARCA4
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
chr11_-_119991589 4.57 ENST00000526881.1
TRIM29
tripartite motif containing 29
chr11_+_65554493 4.15 ENST00000335987.3
OVOL1
ovo-like zinc finger 1
chr1_+_79115503 3.93 ENST00000370747.4
ENST00000438486.1
ENST00000545124.1
IFI44
interferon-induced protein 44
chr1_+_152486950 3.80 ENST00000368790.3
CRCT1
cysteine-rich C-terminal 1
chr12_-_6484376 3.76 ENST00000360168.3
ENST00000358945.3
SCNN1A
sodium channel, non-voltage-gated 1 alpha subunit
chrX_+_43515467 3.72 ENST00000338702.3
ENST00000542639.1
MAOA
monoamine oxidase A
chr3_-_185538849 3.66 ENST00000421047.2
IGF2BP2
insulin-like growth factor 2 mRNA binding protein 2
chr11_-_104905840 3.60 ENST00000526568.1
ENST00000393136.4
ENST00000531166.1
ENST00000534497.1
ENST00000527979.1
ENST00000446369.1
ENST00000353247.5
ENST00000528974.1
ENST00000533400.1
ENST00000525825.1
ENST00000436863.3
CASP1
caspase 1, apoptosis-related cysteine peptidase
chr12_-_50643664 3.43 ENST00000550592.1
LIMA1
LIM domain and actin binding 1
chr22_+_30792980 3.39 ENST00000403484.1
ENST00000405717.3
ENST00000402592.3
SEC14L2
SEC14-like 2 (S. cerevisiae)
chr11_-_104827425 3.21 ENST00000393150.3
CASP4
caspase 4, apoptosis-related cysteine peptidase
chr1_+_158978768 3.10 ENST00000447473.2
IFI16
interferon, gamma-inducible protein 16
chr17_+_1666108 2.97 ENST00000570731.1
SERPINF1
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
chr9_+_135937365 2.88 ENST00000372080.4
ENST00000351304.7
CEL
carboxyl ester lipase
chr5_+_36608422 2.76 ENST00000381918.3
SLC1A3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr11_-_102651343 2.72 ENST00000279441.4
ENST00000539681.1
MMP10
matrix metallopeptidase 10 (stromelysin 2)
chr21_-_27423339 2.66 ENST00000415997.1
APP
amyloid beta (A4) precursor protein
chr12_+_128399965 2.66 ENST00000540882.1
ENST00000542089.1
LINC00507
long intergenic non-protein coding RNA 507
chr3_-_176914191 2.65 ENST00000437738.1
ENST00000424913.1
ENST00000443315.1
TBL1XR1
transducin (beta)-like 1 X-linked receptor 1
chr5_+_150639360 2.61 ENST00000523004.1
GM2A
GM2 ganglioside activator
chr14_-_24711764 2.54 ENST00000557921.1
ENST00000558476.1
TINF2
TERF1 (TRF1)-interacting nuclear factor 2
chr2_+_113816685 2.52 ENST00000393200.2
IL36RN
interleukin 36 receptor antagonist
chr4_+_37455536 2.44 ENST00000381980.4
ENST00000508175.1
C4orf19
chromosome 4 open reading frame 19
chr1_+_174843548 2.41 ENST00000478442.1
ENST00000465412.1
RABGAP1L
RAB GTPase activating protein 1-like
chr12_+_66582919 2.39 ENST00000545837.1
ENST00000457197.2
IRAK3
interleukin-1 receptor-associated kinase 3
chr2_+_113816215 2.37 ENST00000346807.3
IL36RN
interleukin 36 receptor antagonist
chr3_+_121774202 2.37 ENST00000469710.1
ENST00000493101.1
ENST00000330540.2
ENST00000264468.5
CD86
CD86 molecule
chr19_-_36001113 2.35 ENST00000434389.1
DMKN
dermokine
chr2_+_191221240 2.33 ENST00000409027.1
ENST00000458193.1
INPP1
inositol polyphosphate-1-phosphatase
chr3_-_160823040 2.32 ENST00000484127.1
ENST00000492353.1
ENST00000473142.1
ENST00000468268.1
ENST00000460353.1
ENST00000320474.4
ENST00000392781.2
B3GALNT1
beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group)
chr1_+_160370344 2.28 ENST00000368061.2
VANGL2
VANGL planar cell polarity protein 2
chr14_-_24711470 2.26 ENST00000559969.1
TINF2
TERF1 (TRF1)-interacting nuclear factor 2
chr19_+_7895074 2.23 ENST00000270530.4
EVI5L
ecotropic viral integration site 5-like
chr11_-_96076334 2.12 ENST00000524717.1
MAML2
mastermind-like 2 (Drosophila)
chr9_+_124329336 2.10 ENST00000394340.3
ENST00000436835.1
ENST00000259371.2
DAB2IP
DAB2 interacting protein
chr6_+_45296391 2.06 ENST00000371436.6
ENST00000576263.1
RUNX2
runt-related transcription factor 2
chr1_-_68698222 2.00 ENST00000370976.3
ENST00000354777.2
ENST00000262348.4
ENST00000540432.1
WLS
wntless Wnt ligand secretion mediator
chr12_+_128399917 1.97 ENST00000544645.1
LINC00507
long intergenic non-protein coding RNA 507
chr7_-_92777606 1.94 ENST00000437805.1
ENST00000446959.1
ENST00000439952.1
ENST00000414791.1
ENST00000446033.1
ENST00000411955.1
ENST00000318238.4
SAMD9L
sterile alpha motif domain containing 9-like
chr18_+_55888767 1.92 ENST00000431212.2
ENST00000586268.1
ENST00000587190.1
NEDD4L
neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
chr1_-_9953295 1.91 ENST00000377258.1
CTNNBIP1
catenin, beta interacting protein 1
chr3_-_160823158 1.89 ENST00000392779.2
ENST00000392780.1
ENST00000494173.1
B3GALNT1
beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group)
chr14_+_61654271 1.88 ENST00000555185.1
ENST00000557294.1
ENST00000556778.1
PRKCH
protein kinase C, eta
chr14_-_24711865 1.86 ENST00000399423.4
ENST00000267415.7
TINF2
TERF1 (TRF1)-interacting nuclear factor 2
chr8_+_27168988 1.83 ENST00000397501.1
ENST00000338238.4
ENST00000544172.1
PTK2B
protein tyrosine kinase 2 beta
chr1_-_68698197 1.83 ENST00000370973.2
ENST00000370971.1
WLS
wntless Wnt ligand secretion mediator
chr11_-_95523500 1.81 ENST00000540054.1
FAM76B
family with sequence similarity 76, member B
chr11_-_95522907 1.77 ENST00000358780.5
ENST00000542135.1
FAM76B
family with sequence similarity 76, member B
chr11_-_26593677 1.75 ENST00000527569.1
MUC15
mucin 15, cell surface associated
chr18_-_21891460 1.72 ENST00000357041.4
OSBPL1A
oxysterol binding protein-like 1A
chr4_+_144354644 1.71 ENST00000512843.1
GAB1
GRB2-associated binding protein 1
chr4_+_87515454 1.68 ENST00000427191.2
ENST00000436978.1
ENST00000502971.1
PTPN13
protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase)
chr11_-_26593779 1.67 ENST00000529533.1
MUC15
mucin 15, cell surface associated
chr12_+_6419877 1.66 ENST00000536531.1
PLEKHG6
pleckstrin homology domain containing, family G (with RhoGef domain) member 6
chr12_-_6740802 1.65 ENST00000431922.1
LPAR5
lysophosphatidic acid receptor 5
chr3_-_105587879 1.61 ENST00000264122.4
ENST00000403724.1
ENST00000405772.1
CBLB
Cbl proto-oncogene B, E3 ubiquitin protein ligase
chr1_+_16090914 1.61 ENST00000441801.2
FBLIM1
filamin binding LIM protein 1
chr4_+_144312659 1.54 ENST00000509992.1
GAB1
GRB2-associated binding protein 1
chrX_+_37208540 1.46 ENST00000466533.1
ENST00000542554.1
ENST00000543642.1
ENST00000484460.1
ENST00000449135.2
ENST00000463135.1
ENST00000465127.1
PRRG1
TM4SF2
proline rich Gla (G-carboxyglutamic acid) 1
Uncharacterized protein; cDNA FLJ59144, highly similar to Tetraspanin-7
chr12_+_112563335 1.44 ENST00000549358.1
ENST00000257604.5
ENST00000548092.1
ENST00000552896.1
TRAFD1
TRAF-type zinc finger domain containing 1
chr1_+_47489240 1.42 ENST00000371901.3
CYP4X1
cytochrome P450, family 4, subfamily X, polypeptide 1
chr3_+_28390637 1.41 ENST00000420223.1
ENST00000383768.2
ZCWPW2
zinc finger, CW type with PWWP domain 2
chr12_+_112563303 1.41 ENST00000412615.2
TRAFD1
TRAF-type zinc finger domain containing 1
chr11_-_128894053 1.41 ENST00000392657.3
ARHGAP32
Rho GTPase activating protein 32
chr6_-_138833630 1.38 ENST00000533765.1
NHSL1
NHS-like 1
chr6_+_130339710 1.38 ENST00000526087.1
ENST00000533560.1
ENST00000361794.2
L3MBTL3
l(3)mbt-like 3 (Drosophila)
chr2_+_138721850 1.37 ENST00000329366.4
ENST00000280097.3
HNMT
histamine N-methyltransferase
chr1_+_144173162 1.36 ENST00000356801.6
NBPF8
neuroblastoma breakpoint family, member 8
chr6_+_47666275 1.34 ENST00000327753.3
ENST00000283303.2
GPR115
G protein-coupled receptor 115
chr4_-_87515202 1.32 ENST00000502302.1
ENST00000513186.1
MAPK10
mitogen-activated protein kinase 10
chr16_+_31724552 1.28 ENST00000539915.1
ENST00000316491.9
ENST00000399681.3
ENST00000398696.3
ENST00000534369.1
ZNF720
zinc finger protein 720
chr14_-_24711806 1.27 ENST00000540705.1
ENST00000538777.1
ENST00000558566.1
ENST00000559019.1
TINF2
TERF1 (TRF1)-interacting nuclear factor 2
chr7_-_134896234 1.26 ENST00000354475.4
ENST00000344400.5
WDR91
WD repeat domain 91
chr14_+_32798462 1.25 ENST00000280979.4
AKAP6
A kinase (PRKA) anchor protein 6
chr12_-_22063787 1.25 ENST00000544039.1
ABCC9
ATP-binding cassette, sub-family C (CFTR/MRP), member 9
chr4_-_74486109 1.24 ENST00000395777.2
RASSF6
Ras association (RalGDS/AF-6) domain family member 6
chr2_+_191208656 1.24 ENST00000458647.1
INPP1
inositol polyphosphate-1-phosphatase
chr14_+_85994943 1.22 ENST00000553678.1
RP11-497E19.2
Uncharacterized protein
chr17_+_74846230 1.22 ENST00000592919.1
LINC00868
long intergenic non-protein coding RNA 868
chr11_-_95522639 1.20 ENST00000536839.1
FAM76B
family with sequence similarity 76, member B
chr6_-_32095968 1.20 ENST00000375203.3
ENST00000375201.4
ATF6B
activating transcription factor 6 beta
chr9_+_470288 1.19 ENST00000382303.1
KANK1
KN motif and ankyrin repeat domains 1
chr11_-_26593649 1.18 ENST00000455601.2
MUC15
mucin 15, cell surface associated
chr5_+_148737562 1.17 ENST00000274569.4
PCYOX1L
prenylcysteine oxidase 1 like
chr8_-_57123815 1.16 ENST00000316981.3
ENST00000423799.2
ENST00000429357.2
PLAG1
pleiomorphic adenoma gene 1
chr12_-_10022735 1.15 ENST00000228438.2
CLEC2B
C-type lectin domain family 2, member B
chr13_+_102142296 1.15 ENST00000376162.3
ITGBL1
integrin, beta-like 1 (with EGF-like repeat domains)
chr3_+_43732362 1.15 ENST00000458276.2
ABHD5
abhydrolase domain containing 5
chr3_-_105588231 1.10 ENST00000545639.1
ENST00000394027.3
ENST00000438603.1
ENST00000447441.1
ENST00000443752.1
CBLB
Cbl proto-oncogene B, E3 ubiquitin protein ligase
chr16_+_31724618 1.10 ENST00000530881.1
ENST00000529515.1
ZNF720
zinc finger protein 720
chr2_+_87140935 1.06 ENST00000398193.3
RGPD1
RANBP2-like and GRIP domain containing 1
chr2_+_138722028 1.05 ENST00000280096.5
HNMT
histamine N-methyltransferase
chr4_-_102268484 1.04 ENST00000394853.4
PPP3CA
protein phosphatase 3, catalytic subunit, alpha isozyme
chr14_-_73360796 1.04 ENST00000556509.1
ENST00000541685.1
ENST00000546183.1
DPF3
D4, zinc and double PHD fingers, family 3
chr19_-_6737576 1.02 ENST00000601716.1
ENST00000264080.7
GPR108
G protein-coupled receptor 108
chr5_+_36608280 0.98 ENST00000513646.1
SLC1A3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr3_+_158519654 0.98 ENST00000415822.2
ENST00000392813.4
ENST00000264266.8
MFSD1
major facilitator superfamily domain containing 1
chr3_+_186288454 0.98 ENST00000265028.3
DNAJB11
DnaJ (Hsp40) homolog, subfamily B, member 11
chr16_-_21431078 0.97 ENST00000458643.2
NPIPB3
nuclear pore complex interacting protein family, member B3
chr1_-_206671061 0.96 ENST00000367119.1
C1orf147
chromosome 1 open reading frame 147
chr12_+_56521840 0.96 ENST00000394048.5
ESYT1
extended synaptotagmin-like protein 1
chr10_-_135379132 0.96 ENST00000343131.5
SYCE1
synaptonemal complex central element protein 1
chr2_+_191208601 0.93 ENST00000413239.1
ENST00000431594.1
ENST00000444194.1
INPP1
inositol polyphosphate-1-phosphatase
chr2_+_191208791 0.93 ENST00000423767.1
ENST00000451089.1
INPP1
inositol polyphosphate-1-phosphatase
chr7_-_99764853 0.91 ENST00000411994.1
ENST00000426974.2
GAL3ST4
galactose-3-O-sulfotransferase 4
chr11_-_107729887 0.91 ENST00000525815.1
SLC35F2
solute carrier family 35, member F2
chr1_+_81771806 0.90 ENST00000370721.1
ENST00000370727.1
ENST00000370725.1
ENST00000370723.1
ENST00000370728.1
ENST00000370730.1
LPHN2
latrophilin 2
chr7_-_100860851 0.89 ENST00000223127.3
PLOD3
procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3
chrX_+_37208521 0.89 ENST00000378628.4
PRRG1
proline rich Gla (G-carboxyglutamic acid) 1
chr12_+_56522001 0.88 ENST00000267113.4
ENST00000541590.1
ESYT1
extended synaptotagmin-like protein 1
chr6_-_133035185 0.88 ENST00000367928.4
VNN1
vanin 1
chr3_-_143567262 0.88 ENST00000474151.1
ENST00000316549.6
SLC9A9
solute carrier family 9, subfamily A (NHE9, cation proton antiporter 9), member 9
chr4_-_68995571 0.87 ENST00000356291.2
TMPRSS11F
transmembrane protease, serine 11F
chr9_+_131062367 0.85 ENST00000601297.1
AL359091.2
CDNA: FLJ21673 fis, clone COL09042; HCG2036511; Uncharacterized protein
chrX_-_77225135 0.84 ENST00000458128.1
PGAM4
phosphoglycerate mutase family member 4
chr7_-_99764907 0.83 ENST00000413800.1
GAL3ST4
galactose-3-O-sulfotransferase 4
chr8_+_22132810 0.83 ENST00000356766.6
PIWIL2
piwi-like RNA-mediated gene silencing 2
chr2_-_70780572 0.83 ENST00000450929.1
TGFA
transforming growth factor, alpha
chr2_-_169887827 0.83 ENST00000263817.6
ABCB11
ATP-binding cassette, sub-family B (MDR/TAP), member 11
chr13_+_73632897 0.83 ENST00000377687.4
KLF5
Kruppel-like factor 5 (intestinal)
chr4_+_123161120 0.82 ENST00000446180.1
KIAA1109
KIAA1109
chr16_-_28621298 0.82 ENST00000566189.1
SULT1A1
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
chr19_+_54641444 0.81 ENST00000221232.5
ENST00000358389.3
CNOT3
CCR4-NOT transcription complex, subunit 3
chr9_-_5339873 0.80 ENST00000223862.1
ENST00000223858.4
RLN1
relaxin 1
chr19_+_18669809 0.80 ENST00000602094.1
KXD1
KxDL motif containing 1
chr1_-_54879140 0.80 ENST00000525990.1
SSBP3
single stranded DNA binding protein 3
chr2_+_234637754 0.80 ENST00000482026.1
ENST00000609767.1
UGT1A3
UGT1A1
UDP glucuronosyltransferase 1 family, polypeptide A3
UDP glucuronosyltransferase 1 family, polypeptide A8
chr1_+_207226574 0.78 ENST00000367080.3
ENST00000367079.2
PFKFB2
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
chr1_-_54356404 0.77 ENST00000539954.1
YIPF1
Yip1 domain family, member 1
chr2_-_88125471 0.76 ENST00000398146.3
RGPD2
RANBP2-like and GRIP domain containing 2
chr3_-_121740969 0.75 ENST00000393631.1
ENST00000273691.3
ENST00000344209.5
ILDR1
immunoglobulin-like domain containing receptor 1
chr8_+_22132847 0.75 ENST00000521356.1
PIWIL2
piwi-like RNA-mediated gene silencing 2
chr15_+_59279851 0.74 ENST00000348370.4
ENST00000434298.1
ENST00000559160.1
RNF111
ring finger protein 111
chr16_-_28621312 0.73 ENST00000314752.7
SULT1A1
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
chr14_+_57671888 0.73 ENST00000391612.1
AL391152.1
AL391152.1
chr2_+_234545148 0.72 ENST00000373445.1
UGT1A10
UDP glucuronosyltransferase 1 family, polypeptide A10
chr17_+_46970127 0.71 ENST00000355938.5
ATP5G1
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C1 (subunit 9)
chr3_-_186288097 0.69 ENST00000446782.1
TBCCD1
TBCC domain containing 1
chr17_+_40610862 0.68 ENST00000393829.2
ENST00000546249.1
ENST00000537728.1
ENST00000264649.6
ENST00000585525.1
ENST00000343619.4
ENST00000544137.1
ENST00000589727.1
ENST00000587824.1
ATP6V0A1
ATPase, H+ transporting, lysosomal V0 subunit a1
chr12_+_55248289 0.67 ENST00000308796.6
MUCL1
mucin-like 1
chr20_-_5485166 0.66 ENST00000589201.1
ENST00000379053.4
LINC00654
long intergenic non-protein coding RNA 654
chr9_-_116172946 0.66 ENST00000374171.4
POLE3
polymerase (DNA directed), epsilon 3, accessory subunit
chr4_-_176733897 0.66 ENST00000393658.2
GPM6A
glycoprotein M6A
chr2_-_112237835 0.66 ENST00000442293.1
ENST00000439494.1
MIR4435-1HG
MIR4435-1 host gene (non-protein coding)
chr19_-_3985455 0.66 ENST00000309311.6
EEF2
eukaryotic translation elongation factor 2
chr4_+_119199904 0.64 ENST00000602483.1
ENST00000602819.1
SNHG8
small nucleolar RNA host gene 8 (non-protein coding)
chr1_+_24019099 0.64 ENST00000443624.1
ENST00000458455.1
RPL11
ribosomal protein L11
chr20_-_40247002 0.64 ENST00000373222.3
CHD6
chromodomain helicase DNA binding protein 6
chr4_-_25865159 0.63 ENST00000502949.1
ENST00000264868.5
ENST00000513691.1
ENST00000514872.1
SEL1L3
sel-1 suppressor of lin-12-like 3 (C. elegans)
chr2_+_201242941 0.63 ENST00000449647.1
SPATS2L
spermatogenesis associated, serine-rich 2-like
chr19_+_50270219 0.62 ENST00000354293.5
ENST00000359032.5
AP2A1
adaptor-related protein complex 2, alpha 1 subunit
chr14_-_23058063 0.62 ENST00000538631.1
ENST00000543337.1
ENST00000250498.4
DAD1
defender against cell death 1
chrX_-_24690771 0.62 ENST00000379145.1
PCYT1B
phosphate cytidylyltransferase 1, choline, beta
chr16_-_21868739 0.61 ENST00000415645.2
NPIPB4
nuclear pore complex interacting protein family, member B4
chr1_+_144989309 0.60 ENST00000596396.1
AL590452.1
Uncharacterized protein
chr22_-_32766972 0.59 ENST00000382084.4
ENST00000382086.2
RFPL3S
RFPL3 antisense
chr3_+_130745688 0.59 ENST00000510769.1
ENST00000429253.2
ENST00000356918.4
ENST00000510688.1
ENST00000511262.1
ENST00000383366.4
NEK11
NIMA-related kinase 11
chr20_-_40247133 0.58 ENST00000373233.3
ENST00000309279.7
CHD6
chromodomain helicase DNA binding protein 6
chr15_+_92006567 0.58 ENST00000554333.1
RP11-661P17.1
RP11-661P17.1
chr15_-_55562451 0.57 ENST00000568803.1
RAB27A
RAB27A, member RAS oncogene family
chr16_-_21436459 0.56 ENST00000448012.2
ENST00000504841.2
ENST00000419180.2
NPIPB3
nuclear pore complex interacting protein family, member B3
chr5_+_128795958 0.55 ENST00000274487.4
ADAMTS19
ADAM metallopeptidase with thrombospondin type 1 motif, 19
chr14_-_90085458 0.55 ENST00000345097.4
ENST00000555855.1
ENST00000555353.1
FOXN3
forkhead box N3
chr8_-_13134246 0.55 ENST00000503161.2
DLC1
deleted in liver cancer 1
chr11_-_107729504 0.55 ENST00000265836.7
SLC35F2
solute carrier family 35, member F2
chr2_+_29336855 0.55 ENST00000404424.1
CLIP4
CAP-GLY domain containing linker protein family, member 4
chr5_+_110427983 0.54 ENST00000513710.2
ENST00000505303.1
WDR36
WD repeat domain 36
chr4_-_69111401 0.54 ENST00000332644.5
TMPRSS11B
transmembrane protease, serine 11B
chr7_+_90012986 0.54 ENST00000416322.1
CLDN12
claudin 12
chr12_+_122688090 0.53 ENST00000324189.4
ENST00000546192.1
B3GNT4
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4
chr1_-_1710229 0.53 ENST00000341991.3
NADK
NAD kinase
chr4_-_109541539 0.53 ENST00000509984.1
ENST00000507248.1
ENST00000506795.1
RPL34-AS1
RPL34 antisense RNA 1 (head to head)
chr1_-_93257951 0.51 ENST00000543509.1
ENST00000370331.1
ENST00000540033.1
EVI5
ecotropic viral integration site 5
chr16_-_30257122 0.51 ENST00000520915.1
RP11-347C12.1
Putative NPIP-like protein LOC613037
chr22_-_30234218 0.50 ENST00000307790.3
ENST00000542393.1
ENST00000397771.2
ASCC2
activating signal cointegrator 1 complex subunit 2
chr11_-_63439013 0.50 ENST00000398868.3
ATL3
atlastin GTPase 3
chr8_+_27169138 0.49 ENST00000522338.1
PTK2B
protein tyrosine kinase 2 beta
chr16_-_28621353 0.48 ENST00000567512.1
SULT1A1
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
chr3_-_130745403 0.47 ENST00000504725.1
ENST00000509060.1
ASTE1
asteroid homolog 1 (Drosophila)
chr15_-_44969086 0.47 ENST00000434130.1
ENST00000560780.1
PATL2
protein associated with topoisomerase II homolog 2 (yeast)
chr16_+_50730910 0.46 ENST00000300589.2
NOD2
nucleotide-binding oligomerization domain containing 2
chr17_-_73258425 0.46 ENST00000578348.1
ENST00000582486.1
ENST00000582717.1
GGA3
golgi-associated, gamma adaptin ear containing, ARF binding protein 3
chr8_+_39972170 0.46 ENST00000521257.1
RP11-359E19.2
RP11-359E19.2
chr2_+_65215604 0.46 ENST00000531327.1
SLC1A4
solute carrier family 1 (glutamate/neutral amino acid transporter), member 4

Network of associatons between targets according to the STRING database.

First level regulatory network of HOXB3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
5.3 15.9 GO:0070563 negative regulation of vitamin D receptor signaling pathway(GO:0070563)
2.3 11.4 GO:0015688 iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
1.4 8.6 GO:0033031 positive regulation of neutrophil apoptotic process(GO:0033031)
1.0 4.2 GO:1901994 negative regulation of meiotic cell cycle phase transition(GO:1901994)
1.0 7.9 GO:0010836 negative regulation of protein ADP-ribosylation(GO:0010836)
1.0 3.8 GO:0061357 positive regulation of Wnt protein secretion(GO:0061357)
0.9 4.6 GO:0007070 negative regulation of transcription during mitosis(GO:0007068) negative regulation of transcription from RNA polymerase II promoter during mitosis(GO:0007070)
0.9 3.6 GO:0050717 positive regulation of interleukin-1 alpha secretion(GO:0050717)
0.8 2.4 GO:0002644 negative regulation of tolerance induction(GO:0002644) positive regulation of interleukin-4 biosynthetic process(GO:0045404)
0.8 2.3 GO:0060489 orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490)
0.6 4.9 GO:1902714 antifungal humoral response(GO:0019732) negative regulation of interferon-gamma secretion(GO:1902714)
0.5 2.7 GO:0071874 cellular response to norepinephrine stimulus(GO:0071874)
0.4 2.1 GO:0043553 vascular endothelial growth factor receptor-2 signaling pathway(GO:0036324) negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.4 2.4 GO:0001692 histamine metabolic process(GO:0001692)
0.4 2.4 GO:0010936 negative regulation of macrophage cytokine production(GO:0010936)
0.4 1.2 GO:2000393 negative regulation of lamellipodium morphogenesis(GO:2000393)
0.4 1.6 GO:0030718 germ-line stem cell population maintenance(GO:0030718)
0.4 1.2 GO:0030327 prenylated protein catabolic process(GO:0030327)
0.4 1.9 GO:0002528 regulation of vascular permeability involved in acute inflammatory response(GO:0002528)
0.4 3.4 GO:1903265 positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
0.4 4.1 GO:0070777 gamma-aminobutyric acid biosynthetic process(GO:0009449) D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.3 2.4 GO:1903575 cornified envelope assembly(GO:1903575)
0.3 2.3 GO:2000538 regulation of cGMP-mediated signaling(GO:0010752) regulation of B cell chemotaxis(GO:2000537) positive regulation of B cell chemotaxis(GO:2000538)
0.3 1.9 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.3 6.0 GO:0031268 pseudopodium organization(GO:0031268)
0.3 3.0 GO:0060770 negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.3 0.8 GO:2000744 anterior head development(GO:0097065) regulation of anterior head development(GO:2000742) positive regulation of anterior head development(GO:2000744)
0.3 1.0 GO:1905205 positive regulation of connective tissue replacement(GO:1905205)
0.2 6.1 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.2 11.1 GO:0042730 fibrinolysis(GO:0042730)
0.2 3.7 GO:0042420 dopamine catabolic process(GO:0042420)
0.2 0.9 GO:0046946 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.2 2.6 GO:0006689 ganglioside catabolic process(GO:0006689)
0.2 0.8 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
0.2 0.6 GO:1900126 negative regulation of hyaluronan biosynthetic process(GO:1900126)
0.2 2.9 GO:0016127 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.2 1.9 GO:0034350 regulation of glial cell apoptotic process(GO:0034350) negative regulation of glial cell apoptotic process(GO:0034351)
0.2 1.5 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
0.2 2.6 GO:0060613 fat pad development(GO:0060613)
0.2 7.6 GO:0048012 hepatocyte growth factor receptor signaling pathway(GO:0048012)
0.2 0.6 GO:2000435 regulation of protein neddylation(GO:2000434) negative regulation of protein neddylation(GO:2000435)
0.2 2.1 GO:0002051 osteoblast fate commitment(GO:0002051)
0.2 4.4 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.1 2.1 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.1 1.4 GO:0097475 motor neuron migration(GO:0097475)
0.1 0.8 GO:0015722 canalicular bile acid transport(GO:0015722)
0.1 1.9 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.1 1.1 GO:0010898 positive regulation of triglyceride catabolic process(GO:0010898)
0.1 0.4 GO:1902948 regulation of choline O-acetyltransferase activity(GO:1902769) positive regulation of choline O-acetyltransferase activity(GO:1902771) negative regulation of tau-protein kinase activity(GO:1902948) positive regulation of early endosome to recycling endosome transport(GO:1902955) negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902960) negative regulation of neurofibrillary tangle assembly(GO:1902997) negative regulation of aspartic-type peptidase activity(GO:1905246)
0.1 3.2 GO:0035728 response to hepatocyte growth factor(GO:0035728)
0.1 2.7 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.1 0.5 GO:0060584 detection of peptidoglycan(GO:0032499) activation of MAPK activity involved in innate immune response(GO:0035419) regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585) positive regulation of protein K63-linked ubiquitination(GO:1902523)
0.1 0.8 GO:0033133 positive regulation of glucokinase activity(GO:0033133) positive regulation of hexokinase activity(GO:1903301)
0.1 1.2 GO:0036091 positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0036091)
0.1 0.5 GO:0030311 poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.1 2.2 GO:1902018 negative regulation of cilium assembly(GO:1902018)
0.1 0.7 GO:0051684 maintenance of Golgi location(GO:0051684)
0.1 1.3 GO:0007258 JUN phosphorylation(GO:0007258)
0.1 0.7 GO:2001034 positive regulation of double-strand break repair via nonhomologous end joining(GO:2001034)
0.1 2.0 GO:0006068 ethanol catabolic process(GO:0006068)
0.1 6.0 GO:0045824 negative regulation of innate immune response(GO:0045824)
0.1 1.4 GO:0043249 erythrocyte maturation(GO:0043249)
0.1 0.7 GO:0006741 NADP biosynthetic process(GO:0006741)
0.1 0.8 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.1 0.7 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.1 1.6 GO:0033623 regulation of integrin activation(GO:0033623)
0.1 1.2 GO:1990440 positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)
0.1 1.2 GO:0060252 positive regulation of glial cell proliferation(GO:0060252)
0.1 0.4 GO:0007525 somatic muscle development(GO:0007525)
0.1 0.7 GO:0046887 positive regulation of hormone secretion(GO:0046887)
0.1 3.8 GO:0055078 sodium ion homeostasis(GO:0055078)
0.1 0.7 GO:2000767 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183) positive regulation of cytoplasmic translation(GO:2000767)
0.1 0.6 GO:0031572 G2 DNA damage checkpoint(GO:0031572)
0.1 0.9 GO:0033089 positive regulation of T cell differentiation in thymus(GO:0033089) positive regulation of thymocyte aggregation(GO:2000400)
0.1 0.6 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.1 0.5 GO:0006868 glutamine transport(GO:0006868)
0.1 0.6 GO:0006657 CDP-choline pathway(GO:0006657)
0.1 0.3 GO:0046292 formaldehyde metabolic process(GO:0046292)
0.0 0.3 GO:0015692 lead ion transport(GO:0015692)
0.0 0.5 GO:1900119 positive regulation of execution phase of apoptosis(GO:1900119)
0.0 0.9 GO:0098719 sodium ion import(GO:0097369) sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 0.2 GO:2000078 glandular epithelial cell maturation(GO:0002071) type B pancreatic cell maturation(GO:0072560) positive regulation of type B pancreatic cell development(GO:2000078)
0.0 3.9 GO:0070206 protein trimerization(GO:0070206)
0.0 5.3 GO:0016266 O-glycan processing(GO:0016266)
0.0 3.3 GO:0031529 ruffle organization(GO:0031529)
0.0 0.8 GO:0045741 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741)
0.0 0.7 GO:0070070 proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.0 0.4 GO:0051005 negative regulation of lipoprotein lipase activity(GO:0051005)
0.0 0.1 GO:0048241 epinephrine transport(GO:0048241)
0.0 5.4 GO:0043647 inositol phosphate metabolic process(GO:0043647)
0.0 0.3 GO:2000628 regulation of miRNA metabolic process(GO:2000628)
0.0 0.1 GO:0036058 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.0 3.4 GO:0045540 regulation of cholesterol biosynthetic process(GO:0045540)
0.0 8.5 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.2 GO:0021784 postganglionic parasympathetic fiber development(GO:0021784)
0.0 3.0 GO:0030574 collagen catabolic process(GO:0030574)
0.0 1.7 GO:0006699 bile acid biosynthetic process(GO:0006699)
0.0 0.5 GO:0097094 craniofacial suture morphogenesis(GO:0097094)
0.0 0.5 GO:0006307 DNA dealkylation involved in DNA repair(GO:0006307)
0.0 4.6 GO:1900181 negative regulation of protein localization to nucleus(GO:1900181)
0.0 1.0 GO:0007130 synaptonemal complex assembly(GO:0007130)
0.0 0.5 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.0 0.8 GO:0001829 trophectodermal cell differentiation(GO:0001829)
0.0 0.1 GO:0042214 terpene metabolic process(GO:0042214)
0.0 0.9 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0 1.2 GO:0010107 potassium ion import(GO:0010107)
0.0 3.0 GO:0042035 regulation of cytokine biosynthetic process(GO:0042035)
0.0 0.4 GO:0006067 ethanol metabolic process(GO:0006067) ethanol oxidation(GO:0006069)
0.0 1.7 GO:0009311 oligosaccharide metabolic process(GO:0009311)
0.0 2.6 GO:0031338 regulation of vesicle fusion(GO:0031338)
0.0 0.4 GO:0034063 stress granule assembly(GO:0034063)
0.0 0.2 GO:0060087 relaxation of vascular smooth muscle(GO:0060087) negative regulation of platelet aggregation(GO:0090331)
0.0 0.6 GO:0000042 protein targeting to Golgi(GO:0000042)
0.0 0.2 GO:0008627 intrinsic apoptotic signaling pathway in response to osmotic stress(GO:0008627)
0.0 0.7 GO:0032201 telomere maintenance via semi-conservative replication(GO:0032201)
0.0 0.3 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.0 0.7 GO:0051491 positive regulation of filopodium assembly(GO:0051491)
0.0 0.3 GO:0005513 detection of calcium ion(GO:0005513)
0.0 0.6 GO:0018279 protein N-linked glycosylation via asparagine(GO:0018279)
0.0 0.2 GO:0015701 bicarbonate transport(GO:0015701)
0.0 0.4 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.0 0.2 GO:0048312 intracellular distribution of mitochondria(GO:0048312)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 9.5 GO:0010370 perinucleolar chromocenter(GO:0010370)
0.8 7.0 GO:0097169 AIM2 inflammasome complex(GO:0097169)
0.7 2.1 GO:1990032 parallel fiber(GO:1990032)
0.7 2.6 GO:0005889 hydrogen:potassium-exchanging ATPase complex(GO:0005889)
0.6 2.3 GO:0060187 cell pole(GO:0060187)
0.3 2.7 GO:1990812 growth cone filopodium(GO:1990812)
0.2 7.6 GO:0031528 microvillus membrane(GO:0031528)
0.2 6.0 GO:0031143 pseudopodium(GO:0031143)
0.2 5.6 GO:0071565 nBAF complex(GO:0071565)
0.2 1.2 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.1 3.0 GO:0043203 axon hillock(GO:0043203)
0.1 3.9 GO:0034706 sodium channel complex(GO:0034706)
0.1 1.0 GO:0005955 calcineurin complex(GO:0005955)
0.1 3.8 GO:0032839 dendrite cytoplasm(GO:0032839)
0.1 1.0 GO:0000801 central element(GO:0000801)
0.1 0.7 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.1 0.6 GO:0014802 terminal cisterna(GO:0014802)
0.1 1.9 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.1 0.5 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.1 1.5 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.1 9.4 GO:0035580 specific granule lumen(GO:0035580)
0.1 0.7 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.1 1.8 GO:0044232 organelle membrane contact site(GO:0044232)
0.1 0.8 GO:0046581 intercellular canaliculus(GO:0046581)
0.1 2.3 GO:0097440 apical dendrite(GO:0097440)
0.1 0.7 GO:0042788 polysomal ribosome(GO:0042788)
0.1 0.7 GO:0061689 tricellular tight junction(GO:0061689)
0.1 0.8 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.1 0.7 GO:0005721 pericentric heterochromatin(GO:0005721)
0.0 0.3 GO:0070826 paraferritin complex(GO:0070826)
0.0 4.0 GO:0015030 Cajal body(GO:0015030)
0.0 5.1 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 1.2 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 0.4 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.6 GO:0030130 clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.0 5.0 GO:0005796 Golgi lumen(GO:0005796)
0.0 0.4 GO:0035686 sperm fibrous sheath(GO:0035686)
0.0 0.6 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 1.9 GO:0005771 multivesicular body(GO:0005771)
0.0 2.6 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 14.6 GO:0000790 nuclear chromatin(GO:0000790)
0.0 4.1 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 0.8 GO:0031083 BLOC-1 complex(GO:0031083)
0.0 0.8 GO:0097228 sperm principal piece(GO:0097228)
0.0 0.9 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.0 0.3 GO:0017119 Golgi transport complex(GO:0017119)
0.0 9.9 GO:0016607 nuclear speck(GO:0016607)
0.0 2.2 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 0.7 GO:0044295 axonal growth cone(GO:0044295)
0.0 0.5 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.5 GO:0098827 endoplasmic reticulum subcompartment(GO:0098827)
0.0 0.4 GO:0002080 acrosomal membrane(GO:0002080)
0.0 1.7 GO:0030027 lamellipodium(GO:0030027)
0.0 1.2 GO:0032587 ruffle membrane(GO:0032587)
0.0 1.5 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 2.4 GO:0098857 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.0 0.9 GO:0035577 azurophil granule membrane(GO:0035577)
0.0 1.2 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 1.1 GO:0005811 lipid particle(GO:0005811)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 5.4 GO:0052829 inositol-1,4-bisphosphate 1-phosphatase activity(GO:0004441) inositol-1,3,4-trisphosphate 1-phosphatase activity(GO:0052829)
1.1 4.2 GO:0047273 galactosylgalactosylglucosylceramide beta-D-acetylgalactosaminyltransferase activity(GO:0047273)
1.0 4.9 GO:0005152 interleukin-1 receptor antagonist activity(GO:0005152)
0.8 3.4 GO:0008431 vitamin E binding(GO:0008431)
0.4 1.7 GO:0050698 proteoglycan sulfotransferase activity(GO:0050698)
0.4 3.7 GO:0008131 primary amine oxidase activity(GO:0008131)
0.4 4.1 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.4 2.3 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.4 2.9 GO:0004771 sterol esterase activity(GO:0004771)
0.3 1.6 GO:0034584 piRNA binding(GO:0034584)
0.3 1.2 GO:0008281 sulfonylurea receptor activity(GO:0008281)
0.3 2.1 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.3 7.5 GO:0050700 CARD domain binding(GO:0050700)
0.3 2.0 GO:0047894 flavonol 3-sulfotransferase activity(GO:0047894) steroid sulfotransferase activity(GO:0050294)
0.3 2.6 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.3 0.8 GO:0015432 bile acid-exporting ATPase activity(GO:0015432)
0.3 1.9 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.2 0.7 GO:0070506 high-density lipoprotein particle receptor activity(GO:0070506)
0.2 6.1 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.2 4.6 GO:0030957 Tat protein binding(GO:0030957)
0.2 0.9 GO:0033823 procollagen-lysine 5-dioxygenase activity(GO:0008475) procollagen glucosyltransferase activity(GO:0033823) procollagen galactosyltransferase activity(GO:0050211)
0.2 3.8 GO:0031852 mu-type opioid receptor binding(GO:0031852)
0.2 0.8 GO:0004619 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.2 3.8 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.2 2.7 GO:0051425 PTB domain binding(GO:0051425)
0.2 0.7 GO:0032184 SUMO polymer binding(GO:0032184)
0.1 0.9 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.1 1.2 GO:0016670 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor(GO:0016670)
0.1 0.6 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.1 4.1 GO:0031489 myosin V binding(GO:0031489)
0.1 1.9 GO:0019870 potassium channel inhibitor activity(GO:0019870)
0.1 7.9 GO:0042162 telomeric DNA binding(GO:0042162)
0.1 1.3 GO:0004705 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.1 0.5 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.1 4.4 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.1 0.5 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.1 0.8 GO:0004331 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.1 14.1 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.1 0.4 GO:0010465 nerve growth factor receptor activity(GO:0010465)
0.1 21.6 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.1 1.7 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.1 1.3 GO:0008097 5S rRNA binding(GO:0008097)
0.1 3.7 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.1 1.5 GO:0008179 adenylate cyclase binding(GO:0008179)
0.1 1.0 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.1 0.2 GO:0047275 glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275)
0.1 1.9 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.1 0.4 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.1 0.9 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.1 0.5 GO:0015186 L-glutamine transmembrane transporter activity(GO:0015186)
0.1 1.6 GO:0031005 filamin binding(GO:0031005)
0.1 3.4 GO:0003785 actin monomer binding(GO:0003785)
0.0 11.4 GO:0005506 iron ion binding(GO:0005506)
0.0 0.3 GO:0015086 cadmium ion transmembrane transporter activity(GO:0015086) cobalt ion transmembrane transporter activity(GO:0015087) lead ion transmembrane transporter activity(GO:0015094) ferrous iron uptake transmembrane transporter activity(GO:0015639)
0.0 3.4 GO:0016303 1-phosphatidylinositol-3-kinase activity(GO:0016303)
0.0 0.2 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.0 2.5 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 1.2 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.4 GO:0004024 alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
0.0 0.8 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.0 0.7 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 0.6 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0 1.1 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 2.1 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.0 1.7 GO:0015248 sterol transporter activity(GO:0015248)
0.0 0.1 GO:0005277 acetylcholine transmembrane transporter activity(GO:0005277) secondary active organic cation transmembrane transporter activity(GO:0008513) acetate ester transmembrane transporter activity(GO:1901375)
0.0 1.9 GO:0015026 coreceptor activity(GO:0015026)
0.0 3.8 GO:0008013 beta-catenin binding(GO:0008013)
0.0 0.2 GO:0003998 acylphosphatase activity(GO:0003998)
0.0 16.0 GO:0004930 G-protein coupled receptor activity(GO:0004930)
0.0 1.2 GO:0001221 transcription cofactor binding(GO:0001221)
0.0 0.7 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.0 0.2 GO:0004064 arylesterase activity(GO:0004064)
0.0 5.7 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 0.6 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 0.7 GO:0003951 NAD+ kinase activity(GO:0003951)
0.0 2.4 GO:0008170 N-methyltransferase activity(GO:0008170)
0.0 0.8 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.1 GO:0031386 protein tag(GO:0031386)
0.0 0.1 GO:0008079 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.0 0.8 GO:0042169 SH2 domain binding(GO:0042169)
0.0 4.4 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.1 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.0 0.3 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 0.7 GO:0005080 protein kinase C binding(GO:0005080)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 4.6 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.2 19.3 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.1 3.6 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.1 2.3 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.1 3.4 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.1 7.9 PID TELOMERASE PATHWAY Regulation of Telomerase
0.1 3.0 PID CD40 PATHWAY CD40/CD40L signaling
0.1 4.2 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.1 18.5 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1 7.5 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0 2.4 PID IL1 PATHWAY IL1-mediated signaling events
0.0 3.4 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 1.7 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 2.1 PID RAS PATHWAY Regulation of Ras family activation
0.0 3.3 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 3.2 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 3.1 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.0 1.1 PID ARF 3PATHWAY Arf1 pathway
0.0 2.1 PID TXA2PATHWAY Thromboxane A2 receptor signaling
0.0 6.3 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.3 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 2.2 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 0.5 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 6.3 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.2 3.7 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.1 5.3 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.1 1.9 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.1 6.9 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.1 2.1 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.1 4.7 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.1 1.3 REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1 Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.1 2.4 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.1 3.0 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.1 3.2 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.1 2.0 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.1 16.1 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events
0.1 2.7 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.1 3.9 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.1 2.2 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 0.8 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.0 1.6 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 1.2 REACTOME INWARDLY RECTIFYING K CHANNELS Genes involved in Inwardly rectifying K+ channels
0.0 1.5 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.0 1.1 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.5 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.0 0.6 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.0 0.3 REACTOME DESTABILIZATION OF MRNA BY KSRP Genes involved in Destabilization of mRNA by KSRP
0.0 0.6 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.0 0.8 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 0.8 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 0.7 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 3.6 REACTOME TRANSMISSION ACROSS CHEMICAL SYNAPSES Genes involved in Transmission across Chemical Synapses
0.0 8.4 REACTOME HEMOSTASIS Genes involved in Hemostasis
0.0 1.7 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.0 0.6 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 1.0 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.2 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.9 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation