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SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for HOXB4_LHX9

Z-value: 2.33

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Transcription factors associated with HOXB4_LHX9

Gene Symbol Gene ID Gene Info
HOXB4
ENSG00000182742.5 homeobox B4
LHX9
ENSG00000143355.11 LIM homeobox 9

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
LHX9hg19_v2_chr1_+_197881592_197881635-0.811.5e-05Click!
HOXB4hg19_v2_chr17_-_46657473_466574730.521.9e-02Click!

Activity profile of HOXB4_LHX9 motif

Sorted Z-values of HOXB4_LHX9 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr17_-_39743139 31.51 ENST00000167586.6
KRT14
keratin 14
chr10_-_105845674 25.82 ENST00000353479.5
ENST00000369733.3
COL17A1
collagen, type XVII, alpha 1
chr10_-_105845536 21.59 ENST00000393211.3
COL17A1
collagen, type XVII, alpha 1
chrX_+_43515467 14.06 ENST00000338702.3
ENST00000542639.1
MAOA
monoamine oxidase A
chr2_-_161056762 12.92 ENST00000428609.2
ENST00000409967.2
ITGB6
integrin, beta 6
chr2_-_161056802 12.57 ENST00000283249.2
ENST00000409872.1
ITGB6
integrin, beta 6
chr17_+_1674982 11.24 ENST00000572048.1
ENST00000573763.1
SERPINF1
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
chr18_+_29027696 9.69 ENST00000257189.4
DSG3
desmoglein 3
chr11_+_5710919 9.35 ENST00000379965.3
ENST00000425490.1
TRIM22
tripartite motif containing 22
chr19_+_49199209 8.47 ENST00000522966.1
ENST00000425340.2
ENST00000391876.4
FUT2
fucosyltransferase 2 (secretor status included)
chr3_-_151034734 8.34 ENST00000260843.4
GPR87
G protein-coupled receptor 87
chr5_+_66300464 7.75 ENST00000436277.1
MAST4
microtubule associated serine/threonine kinase family member 4
chr9_+_124329336 6.80 ENST00000394340.3
ENST00000436835.1
ENST00000259371.2
DAB2IP
DAB2 interacting protein
chr14_-_67878917 6.80 ENST00000216446.4
PLEK2
pleckstrin 2
chr17_+_66511540 6.76 ENST00000588188.2
PRKAR1A
protein kinase, cAMP-dependent, regulatory, type I, alpha
chr2_+_182850551 6.61 ENST00000452904.1
ENST00000409137.3
ENST00000280295.3
PPP1R1C
protein phosphatase 1, regulatory (inhibitor) subunit 1C
chr7_+_150020363 6.57 ENST00000359623.4
ENST00000493307.1
LRRC61
leucine rich repeat containing 61
chr2_+_102953608 6.39 ENST00000311734.2
ENST00000409584.1
IL1RL1
interleukin 1 receptor-like 1
chr11_-_104827425 6.32 ENST00000393150.3
CASP4
caspase 4, apoptosis-related cysteine peptidase
chr11_-_128894053 6.28 ENST00000392657.3
ARHGAP32
Rho GTPase activating protein 32
chr4_-_74486109 6.23 ENST00000395777.2
RASSF6
Ras association (RalGDS/AF-6) domain family member 6
chr11_-_119991589 6.21 ENST00000526881.1
TRIM29
tripartite motif containing 29
chr2_-_74618907 6.16 ENST00000421392.1
ENST00000437375.1
DCTN1
dynactin 1
chr6_+_130339710 6.13 ENST00000526087.1
ENST00000533560.1
ENST00000361794.2
L3MBTL3
l(3)mbt-like 3 (Drosophila)
chr15_+_94899183 6.09 ENST00000557742.1
MCTP2
multiple C2 domains, transmembrane 2
chr5_+_66300446 6.04 ENST00000261569.7
MAST4
microtubule associated serine/threonine kinase family member 4
chr1_+_160370344 5.79 ENST00000368061.2
VANGL2
VANGL planar cell polarity protein 2
chr7_+_150020329 5.76 ENST00000323078.7
LRRC61
leucine rich repeat containing 61
chr11_-_13011081 5.75 ENST00000532541.1
ENST00000526388.1
ENST00000534477.1
ENST00000531402.1
ENST00000527945.1
ENST00000504230.2
LINC00958
long intergenic non-protein coding RNA 958
chr11_-_327537 5.68 ENST00000602735.1
IFITM3
interferon induced transmembrane protein 3
chr19_-_36001113 5.66 ENST00000434389.1
DMKN
dermokine
chr17_+_57233087 5.51 ENST00000578777.1
ENST00000577457.1
ENST00000582995.1
PRR11
proline rich 11
chr4_+_169418255 5.33 ENST00000505667.1
ENST00000511948.1
PALLD
palladin, cytoskeletal associated protein
chr3_+_195447738 5.31 ENST00000447234.2
ENST00000320736.6
ENST00000436408.1
MUC20
mucin 20, cell surface associated
chr8_-_116504448 5.17 ENST00000518018.1
TRPS1
trichorhinophalangeal syndrome I
chr5_+_81575281 5.16 ENST00000380167.4
ATP6AP1L
ATPase, H+ transporting, lysosomal accessory protein 1-like
chr2_+_182850743 4.87 ENST00000409702.1
PPP1R1C
protein phosphatase 1, regulatory (inhibitor) subunit 1C
chr15_-_53002007 4.65 ENST00000561490.1
FAM214A
family with sequence similarity 214, member A
chr8_-_49833978 4.50 ENST00000020945.1
SNAI2
snail family zinc finger 2
chr8_-_125577940 4.49 ENST00000519168.1
ENST00000395508.2
MTSS1
metastasis suppressor 1
chr8_-_49834299 4.45 ENST00000396822.1
SNAI2
snail family zinc finger 2
chr11_-_107729504 4.43 ENST00000265836.7
SLC35F2
solute carrier family 35, member F2
chr7_+_134528635 4.41 ENST00000445569.2
CALD1
caldesmon 1
chr9_+_22646189 4.40 ENST00000436786.1
RP11-399D6.2
RP11-399D6.2
chr10_+_24755416 4.34 ENST00000396446.1
ENST00000396445.1
ENST00000376451.2
KIAA1217
KIAA1217
chr4_-_90757364 4.33 ENST00000508895.1
SNCA
synuclein, alpha (non A4 component of amyloid precursor)
chr3_-_185538849 4.29 ENST00000421047.2
IGF2BP2
insulin-like growth factor 2 mRNA binding protein 2
chr17_-_45266542 4.28 ENST00000531206.1
ENST00000527547.1
ENST00000446365.2
ENST00000575483.1
ENST00000066544.3
CDC27
cell division cycle 27
chr2_+_191221240 4.24 ENST00000409027.1
ENST00000458193.1
INPP1
inositol polyphosphate-1-phosphatase
chr21_-_28215332 4.15 ENST00000517777.1
ADAMTS1
ADAM metallopeptidase with thrombospondin type 1 motif, 1
chr19_-_14064114 4.04 ENST00000585607.1
ENST00000538517.2
ENST00000587458.1
ENST00000538371.2
PODNL1
podocan-like 1
chr18_+_20494078 3.99 ENST00000579124.1
ENST00000577588.1
ENST00000582354.1
ENST00000581819.1
RBBP8
retinoblastoma binding protein 8
chr14_+_62164340 3.96 ENST00000557538.1
ENST00000539097.1
HIF1A
hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
chr6_-_138866823 3.96 ENST00000342260.5
NHSL1
NHS-like 1
chr5_+_179135246 3.91 ENST00000508787.1
CANX
calnexin
chr11_-_107729287 3.90 ENST00000375682.4
SLC35F2
solute carrier family 35, member F2
chr18_+_21452804 3.76 ENST00000269217.6
LAMA3
laminin, alpha 3
chr3_+_111717511 3.74 ENST00000478951.1
ENST00000393917.2
TAGLN3
transgelin 3
chr18_+_21452964 3.73 ENST00000587184.1
LAMA3
laminin, alpha 3
chr4_-_74486217 3.62 ENST00000335049.5
ENST00000307439.5
RASSF6
Ras association (RalGDS/AF-6) domain family member 6
chr8_-_93978216 3.57 ENST00000517751.1
ENST00000524107.1
TRIQK
triple QxxK/R motif containing
chr5_+_40841410 3.56 ENST00000381677.3
CARD6
caspase recruitment domain family, member 6
chr4_+_37455536 3.50 ENST00000381980.4
ENST00000508175.1
C4orf19
chromosome 4 open reading frame 19
chr5_+_89770664 3.49 ENST00000503973.1
ENST00000399107.1
POLR3G
polymerase (RNA) III (DNA directed) polypeptide G (32kD)
chr6_+_26440700 3.45 ENST00000494393.1
ENST00000482451.1
ENST00000244519.2
ENST00000339789.4
ENST00000471353.1
ENST00000361232.3
ENST00000487627.1
ENST00000496719.1
ENST00000490254.1
ENST00000487272.1
BTN3A3
butyrophilin, subfamily 3, member A3
chr3_-_141747950 3.32 ENST00000497579.1
TFDP2
transcription factor Dp-2 (E2F dimerization partner 2)
chr4_-_74486347 3.29 ENST00000342081.3
RASSF6
Ras association (RalGDS/AF-6) domain family member 6
chr4_+_169552748 3.28 ENST00000504519.1
ENST00000512127.1
PALLD
palladin, cytoskeletal associated protein
chr18_-_32870148 3.18 ENST00000589178.1
ENST00000333206.5
ENST00000592278.1
ENST00000592211.1
ENST00000420878.3
ENST00000383091.2
ENST00000586922.2
ZSCAN30
RP11-158H5.7
zinc finger and SCAN domain containing 30
RP11-158H5.7
chr1_-_109584608 3.10 ENST00000400794.3
ENST00000528747.1
ENST00000369962.3
ENST00000361054.3
WDR47
WD repeat domain 47
chr2_+_102456277 3.10 ENST00000421882.1
MAP4K4
mitogen-activated protein kinase kinase kinase kinase 4
chr7_-_150020814 3.09 ENST00000477871.1
ACTR3C
ARP3 actin-related protein 3 homolog C (yeast)
chr8_-_124553437 3.09 ENST00000517956.1
ENST00000443022.2
FBXO32
F-box protein 32
chr3_+_28390637 3.08 ENST00000420223.1
ENST00000383768.2
ZCWPW2
zinc finger, CW type with PWWP domain 2
chr18_-_74839891 3.02 ENST00000581878.1
MBP
myelin basic protein
chr5_-_176889381 2.98 ENST00000393563.4
ENST00000512501.1
DBN1
drebrin 1
chr5_-_102898465 2.97 ENST00000507423.1
ENST00000230792.2
NUDT12
nudix (nucleoside diphosphate linked moiety X)-type motif 12
chr11_-_107729887 2.97 ENST00000525815.1
SLC35F2
solute carrier family 35, member F2
chr3_+_111718036 2.95 ENST00000455401.2
TAGLN3
transgelin 3
chr1_-_183538319 2.92 ENST00000420553.1
ENST00000419402.1
NCF2
neutrophil cytosolic factor 2
chr18_+_47087055 2.87 ENST00000577628.1
LIPG
lipase, endothelial
chr3_-_141719195 2.83 ENST00000397991.4
TFDP2
transcription factor Dp-2 (E2F dimerization partner 2)
chr15_+_89631647 2.78 ENST00000569550.1
ENST00000565066.1
ENST00000565973.1
ABHD2
abhydrolase domain containing 2
chr6_+_42584847 2.78 ENST00000372883.3
UBR2
ubiquitin protein ligase E3 component n-recognin 2
chr3_+_111717600 2.77 ENST00000273368.4
TAGLN3
transgelin 3
chr3_+_136649311 2.75 ENST00000469404.1
ENST00000467911.1
NCK1
NCK adaptor protein 1
chr11_-_8857248 2.75 ENST00000534248.1
ENST00000530959.1
ENST00000531578.1
ENST00000533225.1
ST5
suppression of tumorigenicity 5
chr16_+_48278178 2.72 ENST00000285737.4
ENST00000535754.1
LONP2
lon peptidase 2, peroxisomal
chr4_-_39979576 2.70 ENST00000303538.8
ENST00000503396.1
PDS5A
PDS5, regulator of cohesion maintenance, homolog A (S. cerevisiae)
chr7_-_87856303 2.67 ENST00000394641.3
SRI
sorcin
chr7_-_150020750 2.66 ENST00000539352.1
ACTR3C
ARP3 actin-related protein 3 homolog C (yeast)
chr5_+_89770696 2.63 ENST00000504930.1
ENST00000514483.1
POLR3G
polymerase (RNA) III (DNA directed) polypeptide G (32kD)
chr12_-_22063787 2.61 ENST00000544039.1
ABCC9
ATP-binding cassette, sub-family C (CFTR/MRP), member 9
chr16_+_82068873 2.61 ENST00000566213.1
HSD17B2
hydroxysteroid (17-beta) dehydrogenase 2
chr4_-_103749205 2.60 ENST00000508249.1
UBE2D3
ubiquitin-conjugating enzyme E2D 3
chrX_-_77225135 2.55 ENST00000458128.1
PGAM4
phosphoglycerate mutase family member 4
chr4_-_103998439 2.54 ENST00000503230.1
ENST00000503818.1
SLC9B2
solute carrier family 9, subfamily B (NHA2, cation proton antiporter 2), member 2
chr8_-_93978333 2.53 ENST00000524037.1
ENST00000520430.1
ENST00000521617.1
TRIQK
triple QxxK/R motif containing
chr1_+_152784447 2.52 ENST00000360090.3
LCE1B
late cornified envelope 1B
chr3_-_122233723 2.50 ENST00000493510.1
ENST00000344337.6
ENST00000476916.1
ENST00000465882.1
KPNA1
karyopherin alpha 1 (importin alpha 5)
chr7_+_134430212 2.50 ENST00000436461.2
CALD1
caldesmon 1
chr4_+_26324474 2.49 ENST00000514675.1
RBPJ
recombination signal binding protein for immunoglobulin kappa J region
chr13_+_110958124 2.47 ENST00000400163.2
COL4A2
collagen, type IV, alpha 2
chr1_+_117963209 2.45 ENST00000449370.2
MAN1A2
mannosidase, alpha, class 1A, member 2
chrX_+_3189861 2.45 ENST00000457435.1
ENST00000420429.2
CXorf28
chromosome X open reading frame 28
chr2_-_128284020 2.42 ENST00000295321.4
ENST00000455721.2
IWS1
IWS1 homolog (S. cerevisiae)
chr7_+_107224364 2.41 ENST00000491150.1
BCAP29
B-cell receptor-associated protein 29
chr1_+_157963063 2.36 ENST00000360089.4
ENST00000368173.3
ENST00000392272.2
KIRREL
kin of IRRE like (Drosophila)
chr7_-_87856280 2.29 ENST00000490437.1
ENST00000431660.1
SRI
sorcin
chr10_-_28571015 2.29 ENST00000375719.3
ENST00000375732.1
MPP7
membrane protein, palmitoylated 7 (MAGUK p55 subfamily member 7)
chr9_-_26947220 2.29 ENST00000520884.1
PLAA
phospholipase A2-activating protein
chr1_-_36020531 2.27 ENST00000440579.1
ENST00000494948.1
KIAA0319L
KIAA0319-like
chr4_-_119759795 2.26 ENST00000419654.2
SEC24D
SEC24 family member D
chrX_+_100663243 2.22 ENST00000316594.5
HNRNPH2
heterogeneous nuclear ribonucleoprotein H2 (H')
chr1_-_47184745 2.22 ENST00000544071.1
EFCAB14
EF-hand calcium binding domain 14
chr8_-_93978357 2.20 ENST00000522925.1
ENST00000522903.1
ENST00000537541.1
ENST00000518748.1
ENST00000519069.1
ENST00000521988.1
TRIQK
triple QxxK/R motif containing
chr5_+_40841276 2.17 ENST00000254691.5
CARD6
caspase recruitment domain family, member 6
chr2_+_201242941 2.16 ENST00000449647.1
SPATS2L
spermatogenesis associated, serine-rich 2-like
chrX_+_1710484 2.14 ENST00000313871.3
ENST00000381261.3
AKAP17A
A kinase (PRKA) anchor protein 17A
chrX_+_107334983 2.13 ENST00000457035.1
ENST00000545696.1
ATG4A
autophagy related 4A, cysteine peptidase
chr4_+_169418195 2.12 ENST00000261509.6
ENST00000335742.7
PALLD
palladin, cytoskeletal associated protein
chr12_+_128399965 2.11 ENST00000540882.1
ENST00000542089.1
LINC00507
long intergenic non-protein coding RNA 507
chr4_+_37978891 2.04 ENST00000446803.2
TBC1D1
TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1
chr3_+_139063372 2.04 ENST00000478464.1
MRPS22
mitochondrial ribosomal protein S22
chr4_+_86525299 2.03 ENST00000512201.1
ARHGAP24
Rho GTPase activating protein 24
chr8_-_42396185 2.03 ENST00000518717.1
SLC20A2
solute carrier family 20 (phosphate transporter), member 2
chr14_+_72064945 2.00 ENST00000537413.1
SIPA1L1
signal-induced proliferation-associated 1 like 1
chr3_+_186692745 1.97 ENST00000438590.1
ST6GAL1
ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
chr2_+_201242715 1.95 ENST00000421573.1
SPATS2L
spermatogenesis associated, serine-rich 2-like
chr5_-_16916624 1.94 ENST00000513882.1
MYO10
myosin X
chr16_-_66583994 1.93 ENST00000564917.1
TK2
thymidine kinase 2, mitochondrial
chr10_+_127585093 1.93 ENST00000368695.1
ENST00000368693.1
FANK1
fibronectin type III and ankyrin repeat domains 1
chr2_-_88285309 1.91 ENST00000420840.2
RGPD2
RANBP2-like and GRIP domain containing 2
chr14_+_104182105 1.91 ENST00000311141.2
ZFYVE21
zinc finger, FYVE domain containing 21
chr12_-_112123524 1.87 ENST00000327551.6
BRAP
BRCA1 associated protein
chr4_-_103749179 1.86 ENST00000502690.1
UBE2D3
ubiquitin-conjugating enzyme E2D 3
chrX_+_107334895 1.84 ENST00000372232.3
ENST00000345734.3
ENST00000372254.3
ATG4A
autophagy related 4A, cysteine peptidase
chr5_-_150473127 1.83 ENST00000521001.1
TNIP1
TNFAIP3 interacting protein 1
chr18_+_21033239 1.78 ENST00000581585.1
ENST00000577501.1
RIOK3
RIO kinase 3
chrX_-_102510120 1.77 ENST00000451678.1
TCEAL8
transcription elongation factor A (SII)-like 8
chr5_-_125930929 1.76 ENST00000553117.1
ENST00000447989.2
ENST00000409134.3
ALDH7A1
aldehyde dehydrogenase 7 family, member A1
chr4_-_185275104 1.75 ENST00000317596.3
RP11-290F5.2
RP11-290F5.2
chr1_-_205091115 1.74 ENST00000264515.6
ENST00000367164.1
RBBP5
retinoblastoma binding protein 5
chr6_-_91296737 1.73 ENST00000369332.3
ENST00000369329.3
MAP3K7
mitogen-activated protein kinase kinase kinase 7
chr18_+_47087390 1.72 ENST00000583083.1
LIPG
lipase, endothelial
chr4_-_109541539 1.72 ENST00000509984.1
ENST00000507248.1
ENST00000506795.1
RPL34-AS1
RPL34 antisense RNA 1 (head to head)
chr10_+_63808970 1.70 ENST00000309334.5
ARID5B
AT rich interactive domain 5B (MRF1-like)
chr20_-_50722183 1.70 ENST00000371523.4
ZFP64
ZFP64 zinc finger protein
chr3_+_111718173 1.69 ENST00000494932.1
TAGLN3
transgelin 3
chr2_+_234637754 1.68 ENST00000482026.1
ENST00000609767.1
UGT1A3
UGT1A1
UDP glucuronosyltransferase 1 family, polypeptide A3
UDP glucuronosyltransferase 1 family, polypeptide A8
chr2_+_187454749 1.68 ENST00000261023.3
ENST00000374907.3
ITGAV
integrin, alpha V
chr6_+_64345698 1.66 ENST00000506783.1
ENST00000481385.2
ENST00000515594.1
ENST00000494284.2
ENST00000262043.3
PHF3
PHD finger protein 3
chr4_-_111120334 1.66 ENST00000503885.1
ELOVL6
ELOVL fatty acid elongase 6
chr4_+_87857538 1.65 ENST00000511442.1
AFF1
AF4/FMR2 family, member 1
chr6_-_82957433 1.64 ENST00000306270.7
IBTK
inhibitor of Bruton agammaglobulinemia tyrosine kinase
chr8_-_30670384 1.63 ENST00000221138.4
ENST00000518243.1
PPP2CB
protein phosphatase 2, catalytic subunit, beta isozyme
chr9_+_125133315 1.62 ENST00000223423.4
ENST00000362012.2
PTGS1
prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
chr10_+_122610853 1.60 ENST00000604585.1
WDR11
WD repeat domain 11
chr14_+_104182061 1.59 ENST00000216602.6
ZFYVE21
zinc finger, FYVE domain containing 21
chr4_-_57547870 1.59 ENST00000381260.3
ENST00000420433.1
ENST00000554144.1
ENST00000557328.1
HOPX
HOP homeobox
chr19_+_21324827 1.58 ENST00000600692.1
ENST00000599296.1
ENST00000594425.1
ENST00000311048.7
ZNF431
zinc finger protein 431
chr4_+_25162253 1.57 ENST00000512921.1
PI4K2B
phosphatidylinositol 4-kinase type 2 beta
chr12_+_128399917 1.54 ENST00000544645.1
LINC00507
long intergenic non-protein coding RNA 507
chr4_+_186990298 1.53 ENST00000296795.3
ENST00000513189.1
TLR3
toll-like receptor 3
chr13_-_36050819 1.53 ENST00000379919.4
MAB21L1
mab-21-like 1 (C. elegans)
chr1_+_78383813 1.52 ENST00000342754.5
NEXN
nexilin (F actin binding protein)
chr4_-_111120132 1.51 ENST00000506625.1
ELOVL6
ELOVL fatty acid elongase 6
chr13_+_111837279 1.50 ENST00000467053.1
ARHGEF7
Rho guanine nucleotide exchange factor (GEF) 7
chrX_+_22050546 1.49 ENST00000379374.4
PHEX
phosphate regulating endopeptidase homolog, X-linked
chr6_-_91296602 1.48 ENST00000369325.3
ENST00000369327.3
MAP3K7
mitogen-activated protein kinase kinase kinase 7
chr2_+_27886330 1.47 ENST00000326019.6
SLC4A1AP
solute carrier family 4 (anion exchanger), member 1, adaptor protein
chr16_+_24549014 1.47 ENST00000564314.1
ENST00000567686.1
RBBP6
retinoblastoma binding protein 6
chr4_+_108745711 1.45 ENST00000394684.4
SGMS2
sphingomyelin synthase 2
chr14_-_75083313 1.44 ENST00000556652.1
ENST00000555313.1
CTD-2207P18.2
CTD-2207P18.2
chr3_-_160823040 1.43 ENST00000484127.1
ENST00000492353.1
ENST00000473142.1
ENST00000468268.1
ENST00000460353.1
ENST00000320474.4
ENST00000392781.2
B3GALNT1
beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group)
chr11_+_35201826 1.43 ENST00000531873.1
CD44
CD44 molecule (Indian blood group)
chrX_+_7137475 1.43 ENST00000217961.4
STS
steroid sulfatase (microsomal), isozyme S
chr7_+_115862858 1.43 ENST00000393481.2
TES
testis derived transcript (3 LIM domains)
chr16_-_28634874 1.41 ENST00000395609.1
ENST00000350842.4
SULT1A1
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
chr14_-_104387888 1.40 ENST00000286953.3
C14orf2
chromosome 14 open reading frame 2
chr10_-_116418053 1.40 ENST00000277895.5
ABLIM1
actin binding LIM protein 1
chr7_-_150020578 1.38 ENST00000478393.1
ACTR3C
ARP3 actin-related protein 3 homolog C (yeast)
chr2_-_169887827 1.38 ENST00000263817.6
ABCB11
ATP-binding cassette, sub-family B (MDR/TAP), member 11
chr18_-_47018897 1.37 ENST00000418495.1
RPL17
ribosomal protein L17
chr1_+_174669653 1.37 ENST00000325589.5
RABGAP1L
RAB GTPase activating protein 1-like
chr5_-_159546396 1.37 ENST00000523662.1
ENST00000456329.3
ENST00000307063.7
PWWP2A
PWWP domain containing 2A
chr14_-_74551096 1.35 ENST00000350259.4
ALDH6A1
aldehyde dehydrogenase 6 family, member A1
chr2_-_74618964 1.33 ENST00000417090.1
ENST00000409868.1
DCTN1
dynactin 1
chr6_+_129204337 1.33 ENST00000421865.2
LAMA2
laminin, alpha 2
chr6_-_109702885 1.32 ENST00000504373.1
CD164
CD164 molecule, sialomucin
chr14_+_35591509 1.31 ENST00000604073.1
KIAA0391
KIAA0391
chr9_-_99540328 1.30 ENST00000223428.4
ENST00000375231.1
ENST00000374641.3
ZNF510
zinc finger protein 510
chr11_+_59522837 1.30 ENST00000437946.2
STX3
syntaxin 3
chr5_+_1225470 1.28 ENST00000324642.3
ENST00000296821.4
SLC6A18
solute carrier family 6 (neutral amino acid transporter), member 18
chr8_+_104310661 1.28 ENST00000522566.1
FZD6
frizzled family receptor 6
chr17_+_18086392 1.27 ENST00000541285.1
ALKBH5
alkB, alkylation repair homolog 5 (E. coli)
chr10_+_99205894 1.27 ENST00000370854.3
ENST00000393760.1
ENST00000414567.1
ENST00000370846.4
ZDHHC16
zinc finger, DHHC-type containing 16
chr16_-_66764119 1.25 ENST00000569320.1
DYNC1LI2
dynein, cytoplasmic 1, light intermediate chain 2
chr19_+_58694396 1.22 ENST00000326804.4
ENST00000345813.3
ENST00000424679.2
ZNF274
zinc finger protein 274
chr4_-_103749313 1.21 ENST00000394803.5
UBE2D3
ubiquitin-conjugating enzyme E2D 3

Network of associatons between targets according to the STRING database.

First level regulatory network of HOXB4_LHX9

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
5.3 31.5 GO:0045110 intermediate filament bundle assembly(GO:0045110)
3.0 9.0 GO:0070563 negative regulation of vitamin D receptor signaling pathway(GO:0070563)
2.5 27.2 GO:0038044 transforming growth factor-beta secretion(GO:0038044)
1.9 5.8 GO:0060489 orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490)
1.5 54.9 GO:0031581 hemidesmosome assembly(GO:0031581)
1.5 10.5 GO:0071279 cellular response to cobalt ion(GO:0071279)
1.4 6.8 GO:0043553 vascular endothelial growth factor receptor-2 signaling pathway(GO:0036324) negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
1.1 4.6 GO:0010983 positive regulation of high-density lipoprotein particle clearance(GO:0010983)
1.0 4.0 GO:0035188 blastocyst hatching(GO:0001835) hatching(GO:0035188) organism emergence from protective structure(GO:0071684)
1.0 4.0 GO:0051541 elastin metabolic process(GO:0051541)
1.0 3.0 GO:0019364 NADP catabolic process(GO:0006742) pyridine nucleotide catabolic process(GO:0019364)
0.9 8.4 GO:0090063 positive regulation of microtubule nucleation(GO:0090063)
0.9 2.8 GO:1903676 regulation of cap-dependent translational initiation(GO:1903674) positive regulation of cap-dependent translational initiation(GO:1903676)
0.9 6.4 GO:0038172 interleukin-33-mediated signaling pathway(GO:0038172)
0.9 14.1 GO:0042420 dopamine catabolic process(GO:0042420)
0.9 4.3 GO:0045914 negative regulation of catecholamine metabolic process(GO:0045914) negative regulation of dopamine metabolic process(GO:0045963) negative regulation of dopamine uptake involved in synaptic transmission(GO:0051585) norepinephrine uptake(GO:0051620) regulation of norepinephrine uptake(GO:0051621) negative regulation of norepinephrine uptake(GO:0051622) negative regulation of catecholamine uptake involved in synaptic transmission(GO:0051945) regulation of glutathione peroxidase activity(GO:1903282) positive regulation of glutathione peroxidase activity(GO:1903284) positive regulation of hydrogen peroxide catabolic process(GO:1903285) positive regulation of peroxidase activity(GO:2000470)
0.8 5.7 GO:1903575 cornified envelope assembly(GO:1903575)
0.8 2.4 GO:0097198 histone H3-K36 trimethylation(GO:0097198)
0.7 6.3 GO:1903265 positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
0.6 4.5 GO:0030035 microspike assembly(GO:0030035)
0.6 2.5 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
0.6 5.0 GO:0006880 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.6 4.0 GO:0051697 protein delipidation(GO:0051697)
0.6 8.5 GO:0019317 fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355)
0.6 2.8 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.5 4.6 GO:2001206 positive regulation of osteoclast development(GO:2001206)
0.5 2.6 GO:0046092 deoxycytidine metabolic process(GO:0046092)
0.5 3.0 GO:1904207 regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904207) positive regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904209)
0.5 3.0 GO:0010643 cell communication by chemical coupling(GO:0010643)
0.4 7.2 GO:0043249 erythrocyte maturation(GO:0043249)
0.4 1.8 GO:0031455 glycine betaine biosynthetic process from choline(GO:0019285) glycine betaine metabolic process(GO:0031455) glycine betaine biosynthetic process(GO:0031456)
0.4 10.7 GO:0003334 keratinocyte development(GO:0003334)
0.4 1.5 GO:0034344 type III interferon production(GO:0034343) regulation of type III interferon production(GO:0034344) positive regulation of interferon-alpha biosynthetic process(GO:0045356)
0.4 1.5 GO:0019859 pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
0.4 1.8 GO:0052250 modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032)
0.4 9.2 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.4 6.8 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.4 1.8 GO:0039534 negative regulation of MDA-5 signaling pathway(GO:0039534)
0.4 2.5 GO:1904381 Golgi apparatus mannose trimming(GO:1904381)
0.3 1.0 GO:1904956 regulation of midbrain dopaminergic neuron differentiation(GO:1904956)
0.3 1.7 GO:0070980 biphenyl catabolic process(GO:0070980)
0.3 1.7 GO:0071460 cellular response to cell-matrix adhesion(GO:0071460)
0.3 1.3 GO:0035880 embryonic nail plate morphogenesis(GO:0035880)
0.3 2.5 GO:1901295 positive regulation of ephrin receptor signaling pathway(GO:1901189) regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901295) positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) regulation of canonical Wnt signaling pathway involved in heart development(GO:1905066) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068)
0.3 1.5 GO:0014886 transition between slow and fast fiber(GO:0014886)
0.3 3.7 GO:0090646 mitochondrial tRNA processing(GO:0090646)
0.3 3.2 GO:0019367 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.3 1.3 GO:0035513 oxidative RNA demethylation(GO:0035513) oxidative single-stranded RNA demethylation(GO:0035553)
0.3 2.3 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
0.2 1.5 GO:1904383 response to sodium phosphate(GO:1904383)
0.2 4.0 GO:0097475 motor neuron migration(GO:0097475)
0.2 11.5 GO:1900087 positive regulation of G1/S transition of mitotic cell cycle(GO:1900087)
0.2 1.4 GO:0015722 canalicular bile acid transport(GO:0015722)
0.2 2.3 GO:0071896 protein localization to adherens junction(GO:0071896)
0.2 0.9 GO:0070318 positive regulation of G0 to G1 transition(GO:0070318)
0.2 0.9 GO:0052362 multi-organism catabolic process(GO:0044035) development of symbiont involved in interaction with host(GO:0044115) modulation of development of symbiont involved in interaction with host(GO:0044145) negative regulation of development of symbiont involved in interaction with host(GO:0044147) metabolism of substance in other organism involved in symbiotic interaction(GO:0052214) catabolism of substance in other organism involved in symbiotic interaction(GO:0052227) metabolism of macromolecule in other organism involved in symbiotic interaction(GO:0052229) catabolism by host of symbiont macromolecule(GO:0052360) catabolism by organism of macromolecule in other organism involved in symbiotic interaction(GO:0052361) catabolism by host of symbiont protein(GO:0052362) catabolism by organism of protein in other organism involved in symbiotic interaction(GO:0052363) catabolism by host of substance in symbiont(GO:0052364) metabolism by host of symbiont macromolecule(GO:0052416) metabolism by host of symbiont protein(GO:0052417) metabolism by organism of protein in other organism involved in symbiotic interaction(GO:0052418) metabolism by host of substance in symbiont(GO:0052419)
0.2 2.4 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.2 3.9 GO:0001542 ovulation from ovarian follicle(GO:0001542)
0.2 10.5 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.2 4.2 GO:0014870 response to muscle inactivity(GO:0014870)
0.2 0.5 GO:0002476 antigen processing and presentation of endogenous peptide antigen via MHC class Ib(GO:0002476)
0.2 3.9 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.2 5.2 GO:0046597 negative regulation of viral entry into host cell(GO:0046597)
0.2 1.3 GO:0098967 exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967)
0.2 3.5 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.2 1.4 GO:1900625 regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.2 3.6 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.2 7.7 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.2 1.2 GO:0046952 ketone body catabolic process(GO:0046952)
0.1 0.7 GO:2000521 negative regulation of immunological synapse formation(GO:2000521) negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:2001189)
0.1 6.1 GO:0006359 regulation of transcription from RNA polymerase III promoter(GO:0006359)
0.1 1.7 GO:0072520 seminiferous tubule development(GO:0072520)
0.1 8.1 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.1 2.7 GO:0010992 ubiquitin homeostasis(GO:0010992)
0.1 1.1 GO:1990253 cellular response to leucine starvation(GO:1990253)
0.1 6.0 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.1 1.5 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.1 3.9 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.1 0.5 GO:0032053 ciliary basal body organization(GO:0032053)
0.1 4.8 GO:0048012 hepatocyte growth factor receptor signaling pathway(GO:0048012)
0.1 0.7 GO:2000301 negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.1 1.0 GO:0044829 positive regulation by host of viral genome replication(GO:0044829)
0.1 2.0 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.1 2.7 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)
0.1 1.3 GO:0032224 positive regulation of synaptic transmission, cholinergic(GO:0032224)
0.1 3.8 GO:0048240 sperm capacitation(GO:0048240)
0.1 2.3 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.1 2.3 GO:0006068 ethanol catabolic process(GO:0006068)
0.1 1.2 GO:0098814 spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.1 0.4 GO:0046338 phosphatidylethanolamine catabolic process(GO:0046338)
0.1 2.6 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.1 1.3 GO:0018243 protein O-linked glycosylation via threonine(GO:0018243)
0.1 2.5 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063)
0.1 0.4 GO:0043324 eye pigment biosynthetic process(GO:0006726) eye pigment metabolic process(GO:0042441) pigment metabolic process involved in developmental pigmentation(GO:0043324) pigment metabolic process involved in pigmentation(GO:0043474)
0.1 1.5 GO:1904424 regulation of GTP binding(GO:1904424)
0.1 3.3 GO:0015991 ATP hydrolysis coupled proton transport(GO:0015991)
0.1 1.2 GO:1900112 regulation of histone H3-K9 trimethylation(GO:1900112)
0.1 1.5 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.1 2.0 GO:0006054 N-acetylneuraminate metabolic process(GO:0006054)
0.1 2.6 GO:0000042 protein targeting to Golgi(GO:0000042)
0.1 0.3 GO:0009597 detection of virus(GO:0009597)
0.1 1.7 GO:0008285 negative regulation of cell proliferation(GO:0008285)
0.1 0.8 GO:0098856 intestinal cholesterol absorption(GO:0030299) intestinal lipid absorption(GO:0098856)
0.1 3.5 GO:0006458 'de novo' protein folding(GO:0006458)
0.1 2.6 GO:0018149 peptide cross-linking(GO:0018149)
0.1 9.4 GO:0010508 positive regulation of autophagy(GO:0010508)
0.1 9.6 GO:0070268 cornification(GO:0070268)
0.1 1.6 GO:0001829 trophectodermal cell differentiation(GO:0001829) chaperone-mediated protein complex assembly(GO:0051131)
0.1 4.4 GO:1904893 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.1 0.4 GO:0061767 negative regulation of lung blood pressure(GO:0061767)
0.1 1.0 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
0.1 2.7 GO:0006515 misfolded or incompletely synthesized protein catabolic process(GO:0006515)
0.1 0.5 GO:0030242 pexophagy(GO:0030242)
0.0 1.4 GO:0006706 steroid catabolic process(GO:0006706)
0.0 0.3 GO:0052565 response to defense-related nitric oxide production by other organism involved in symbiotic interaction(GO:0052551) response to defense-related host nitric oxide production(GO:0052565)
0.0 0.2 GO:1904798 positive regulation of core promoter binding(GO:1904798)
0.0 1.0 GO:0060044 negative regulation of cardiac muscle cell proliferation(GO:0060044)
0.0 2.6 GO:0010107 potassium ion import(GO:0010107)
0.0 0.6 GO:0015727 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873)
0.0 1.7 GO:0018345 protein palmitoylation(GO:0018345)
0.0 0.8 GO:0072643 interferon-gamma secretion(GO:0072643)
0.0 0.3 GO:1903826 arginine transmembrane transport(GO:1903826)
0.0 4.3 GO:0042035 regulation of cytokine biosynthetic process(GO:0042035)
0.0 0.5 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.0 0.2 GO:0061107 seminal vesicle development(GO:0061107)
0.0 5.4 GO:1900181 negative regulation of protein localization to nucleus(GO:1900181)
0.0 1.7 GO:0016577 histone demethylation(GO:0016577)
0.0 0.7 GO:0006474 N-terminal protein amino acid acetylation(GO:0006474)
0.0 1.3 GO:0045730 respiratory burst(GO:0045730)
0.0 0.2 GO:0048842 positive regulation of axon extension involved in axon guidance(GO:0048842)
0.0 1.1 GO:0061099 negative regulation of protein tyrosine kinase activity(GO:0061099)
0.0 0.4 GO:0051096 positive regulation of helicase activity(GO:0051096)
0.0 5.0 GO:0090630 activation of GTPase activity(GO:0090630)
0.0 2.7 GO:0016266 O-glycan processing(GO:0016266)
0.0 0.2 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.0 0.3 GO:2000622 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.0 1.7 GO:1904837 beta-catenin-TCF complex assembly(GO:1904837)
0.0 3.1 GO:0046847 filopodium assembly(GO:0046847)
0.0 2.4 GO:0007588 excretion(GO:0007588)
0.0 1.1 GO:1901998 toxin transport(GO:1901998)
0.0 0.1 GO:0090402 oncogene-induced cell senescence(GO:0090402)
0.0 0.9 GO:0051764 actin crosslink formation(GO:0051764)
0.0 1.3 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 3.4 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.0 1.5 GO:0061053 somite development(GO:0061053)
0.0 0.8 GO:0060285 cilium-dependent cell motility(GO:0060285)
0.0 1.6 GO:0046677 response to antibiotic(GO:0046677)
0.0 0.5 GO:2000010 positive regulation of protein localization to cell surface(GO:2000010)
0.0 3.4 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.0 0.3 GO:2000726 negative regulation of cardiac muscle cell differentiation(GO:2000726)
0.0 1.4 GO:0030032 lamellipodium assembly(GO:0030032)
0.0 0.6 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0 0.2 GO:0098719 sodium ion import(GO:0097369) sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 7.1 GO:0018105 peptidyl-serine phosphorylation(GO:0018105)
0.0 3.1 GO:0019722 calcium-mediated signaling(GO:0019722)
0.0 0.4 GO:0006833 water transport(GO:0006833)
0.0 0.1 GO:0014717 regulation of satellite cell activation involved in skeletal muscle regeneration(GO:0014717) satellite cell activation involved in skeletal muscle regeneration(GO:0014901)
0.0 6.9 GO:0031346 positive regulation of cell projection organization(GO:0031346)
0.0 2.0 GO:0098869 cellular oxidant detoxification(GO:0098869)
0.0 0.8 GO:0002763 positive regulation of myeloid leukocyte differentiation(GO:0002763)
0.0 1.0 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 0.4 GO:0031468 nuclear envelope reassembly(GO:0031468)
0.0 0.3 GO:1902895 positive regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902895)
0.0 2.4 GO:0048706 embryonic skeletal system development(GO:0048706)
0.0 1.6 GO:0043433 negative regulation of sequence-specific DNA binding transcription factor activity(GO:0043433)
0.0 0.4 GO:0061049 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0 0.1 GO:2000628 regulation of miRNA metabolic process(GO:2000628)
0.0 1.1 GO:0048207 vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208)
0.0 1.1 GO:0002456 T cell mediated immunity(GO:0002456)
0.0 0.2 GO:2000479 regulation of cAMP-dependent protein kinase activity(GO:2000479)
0.0 0.2 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.0 0.6 GO:0032755 positive regulation of interleukin-6 production(GO:0032755)
0.0 1.4 GO:0070125 mitochondrial translational elongation(GO:0070125)
0.0 5.2 GO:0051056 regulation of small GTPase mediated signal transduction(GO:0051056)
0.0 1.3 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.0 1.4 GO:0043484 regulation of RNA splicing(GO:0043484)
0.0 0.6 GO:0007219 Notch signaling pathway(GO:0007219)
0.0 0.2 GO:0016446 somatic hypermutation of immunoglobulin genes(GO:0016446)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
9.1 27.2 GO:0034685 integrin alphav-beta6 complex(GO:0034685)
2.3 6.8 GO:1990032 parallel fiber(GO:1990032)
1.5 47.4 GO:0030056 hemidesmosome(GO:0030056)
1.4 5.8 GO:0060187 cell pole(GO:0060187)
0.7 6.3 GO:0097169 AIM2 inflammasome complex(GO:0097169)
0.7 7.5 GO:0005610 laminin-5 complex(GO:0005610)
0.6 5.0 GO:0044326 dendritic spine neck(GO:0044326)
0.5 8.4 GO:0005869 dynactin complex(GO:0005869)
0.5 11.2 GO:0043203 axon hillock(GO:0043203)
0.5 3.7 GO:0030678 mitochondrial ribonuclease P complex(GO:0030678)
0.5 6.9 GO:0030478 actin cap(GO:0030478)
0.4 36.8 GO:0045178 basal part of cell(GO:0045178)
0.3 3.8 GO:0097524 sperm plasma membrane(GO:0097524)
0.3 8.1 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.3 2.6 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.3 1.3 GO:1990796 photoreceptor cell terminal bouton(GO:1990796)
0.3 5.2 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.3 0.9 GO:0042585 germinal vesicle(GO:0042585)
0.3 2.9 GO:0032010 phagolysosome(GO:0032010)
0.3 1.7 GO:0034991 nuclear meiotic cohesin complex(GO:0034991)
0.3 1.1 GO:1902912 pyruvate kinase complex(GO:1902912)
0.3 2.5 GO:0005587 collagen type IV trimer(GO:0005587)
0.3 6.8 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.2 3.9 GO:0044233 ER-mitochondrion membrane contact site(GO:0044233)
0.2 2.2 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.2 6.1 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.2 3.0 GO:0033269 internode region of axon(GO:0033269)
0.2 1.0 GO:0070852 cell body fiber(GO:0070852)
0.2 7.9 GO:0030057 desmosome(GO:0030057)
0.2 1.1 GO:1990131 Gtr1-Gtr2 GTPase complex(GO:1990131)
0.2 8.2 GO:0031258 lamellipodium membrane(GO:0031258)
0.2 0.9 GO:1990667 PCSK9-AnxA2 complex(GO:1990667)
0.2 7.2 GO:0097228 sperm principal piece(GO:0097228)
0.1 1.8 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.1 10.7 GO:0002102 podosome(GO:0002102)
0.1 0.7 GO:0031417 NatC complex(GO:0031417)
0.1 2.3 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.1 3.8 GO:0036020 endolysosome membrane(GO:0036020)
0.1 3.2 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671) IkappaB kinase complex(GO:0008385)
0.1 1.7 GO:0044666 MLL3/4 complex(GO:0044666)
0.1 1.4 GO:0046581 intercellular canaliculus(GO:0046581)
0.1 2.6 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.1 1.5 GO:0000322 storage vacuole(GO:0000322)
0.1 4.3 GO:0005680 anaphase-promoting complex(GO:0005680)
0.1 4.3 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.1 9.1 GO:0015030 Cajal body(GO:0015030)
0.1 2.5 GO:0030127 COPII vesicle coat(GO:0030127)
0.1 1.9 GO:0032433 filopodium tip(GO:0032433)
0.1 0.3 GO:0070939 Dsl1p complex(GO:0070939)
0.1 0.5 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.1 5.7 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.1 0.5 GO:0042825 TAP complex(GO:0042825)
0.1 3.1 GO:0005921 gap junction(GO:0005921)
0.1 10.4 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.1 3.2 GO:0001533 cornified envelope(GO:0001533)
0.1 0.4 GO:1990730 VCP-NSFL1C complex(GO:1990730)
0.1 1.7 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.1 0.3 GO:0070931 Golgi-associated vesicle lumen(GO:0070931)
0.1 0.4 GO:0002177 manchette(GO:0002177)
0.1 0.3 GO:0071148 TEAD-1-YAP complex(GO:0071148)
0.1 3.5 GO:1904115 axon cytoplasm(GO:1904115)
0.1 0.2 GO:0036027 protein C inhibitor-TMPRSS7 complex(GO:0036024) protein C inhibitor-TMPRSS11E complex(GO:0036025) protein C inhibitor-PLAT complex(GO:0036026) protein C inhibitor-PLAU complex(GO:0036027) protein C inhibitor-thrombin complex(GO:0036028) protein C inhibitor-KLK3 complex(GO:0036029) protein C inhibitor-plasma kallikrein complex(GO:0036030) serine protease inhibitor complex(GO:0097180) protein C inhibitor-coagulation factor V complex(GO:0097181) protein C inhibitor-coagulation factor Xa complex(GO:0097182) protein C inhibitor-coagulation factor XI complex(GO:0097183)
0.1 4.8 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 1.4 GO:0097517 stress fiber(GO:0001725) actin filament bundle(GO:0032432) contractile actin filament bundle(GO:0097517)
0.0 5.2 GO:0005604 basement membrane(GO:0005604)
0.0 10.6 GO:0043209 myelin sheath(GO:0043209)
0.0 1.6 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 1.2 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 1.3 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 1.4 GO:0005763 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 11.0 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.0 0.4 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.0 0.2 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.0 4.5 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 1.7 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 11.2 GO:0000790 nuclear chromatin(GO:0000790)
0.0 4.6 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 5.2 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.0 3.6 GO:0005925 focal adhesion(GO:0005925)
0.0 1.6 GO:0043198 dendritic shaft(GO:0043198)
0.0 2.7 GO:0005796 Golgi lumen(GO:0005796)
0.0 3.9 GO:0001650 fibrillar center(GO:0001650)
0.0 2.8 GO:0005643 nuclear pore(GO:0005643)
0.0 0.9 GO:0016592 mediator complex(GO:0016592)
0.0 7.5 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 0.4 GO:0033162 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.0 1.1 GO:0005801 cis-Golgi network(GO:0005801)
0.0 3.4 GO:0000785 chromatin(GO:0000785)
0.0 1.7 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 1.1 GO:0031594 neuromuscular junction(GO:0031594)
0.0 0.8 GO:0031526 brush border membrane(GO:0031526)
0.0 0.6 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.6 GO:0005747 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 1.3 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 6.6 GO:0005759 mitochondrial matrix(GO:0005759)
0.0 0.5 GO:0001772 immunological synapse(GO:0001772)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
4.5 31.5 GO:1990254 keratin filament binding(GO:1990254)
2.1 6.4 GO:0002113 interleukin-33 binding(GO:0002113)
1.6 14.1 GO:0008131 primary amine oxidase activity(GO:0008131)
1.2 4.6 GO:0010348 lithium:proton antiporter activity(GO:0010348)
1.0 6.8 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.9 4.3 GO:0060961 phospholipase D inhibitor activity(GO:0060961)
0.8 4.2 GO:0052829 inositol-1,4-bisphosphate 1-phosphatase activity(GO:0004441) inositol-1,3,4-trisphosphate 1-phosphatase activity(GO:0052829)
0.8 11.5 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.7 2.7 GO:0016005 phospholipase A2 activator activity(GO:0016005)
0.7 2.6 GO:0008281 sulfonylurea receptor activity(GO:0008281)
0.6 2.6 GO:0047273 galactosylgalactosylglucosylceramide beta-D-acetylgalactosaminyltransferase activity(GO:0047273)
0.6 2.5 GO:0004082 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.6 3.5 GO:0047006 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity(GO:0047006)
0.6 1.7 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.6 2.8 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
0.5 2.5 GO:0035529 NADH pyrophosphatase activity(GO:0035529)
0.5 1.4 GO:0015432 bile acid-exporting ATPase activity(GO:0015432)
0.4 8.5 GO:0008417 fucosyltransferase activity(GO:0008417)
0.4 3.5 GO:0000285 1-phosphatidylinositol-3-phosphate 5-kinase activity(GO:0000285)
0.4 2.6 GO:0004137 deoxycytidine kinase activity(GO:0004137) thymidine kinase activity(GO:0004797)
0.4 2.0 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.4 9.2 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.3 2.7 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.3 2.3 GO:0047894 flavonol 3-sulfotransferase activity(GO:0047894)
0.3 1.6 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.3 4.4 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.3 3.1 GO:0004111 creatine kinase activity(GO:0004111)
0.3 1.2 GO:0008260 3-oxoacid CoA-transferase activity(GO:0008260)
0.3 2.1 GO:0070728 leucine binding(GO:0070728)
0.3 6.8 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.3 3.2 GO:0102337 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.3 1.3 GO:0035515 oxidative RNA demethylase activity(GO:0035515)
0.3 6.3 GO:0050700 CARD domain binding(GO:0050700)
0.2 0.9 GO:0036033 mediator complex binding(GO:0036033)
0.2 2.0 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.2 3.8 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.2 1.5 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.2 3.7 GO:0004526 ribonuclease P activity(GO:0004526)
0.2 6.9 GO:0005523 tropomyosin binding(GO:0005523)
0.2 4.0 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.2 2.0 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.2 1.8 GO:0089720 caspase binding(GO:0089720)
0.2 1.1 GO:0004743 pyruvate kinase activity(GO:0004743)
0.2 21.5 GO:0001618 virus receptor activity(GO:0001618)
0.2 3.0 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.2 5.7 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.2 1.9 GO:0060002 plus-end directed microfilament motor activity(GO:0060002)
0.2 8.4 GO:0070840 dynein complex binding(GO:0070840)
0.2 1.6 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.2 7.1 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.2 2.9 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.2 5.2 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.1 5.1 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.1 0.7 GO:0019863 IgE binding(GO:0019863)
0.1 1.3 GO:0050544 arachidonic acid binding(GO:0050544)
0.1 0.4 GO:0072544 L-DOPA receptor activity(GO:0035643) L-DOPA binding(GO:0072544)
0.1 3.0 GO:0005522 profilin binding(GO:0005522)
0.1 0.5 GO:0015433 peptide antigen-transporting ATPase activity(GO:0015433)
0.1 5.0 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.1 5.9 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.1 4.4 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.1 6.1 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899)
0.1 3.9 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.1 5.1 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.1 2.1 GO:0034185 apolipoprotein binding(GO:0034185)
0.1 2.3 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 0.8 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.1 2.3 GO:0098748 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.1 4.5 GO:0003785 actin monomer binding(GO:0003785)
0.1 1.0 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.1 0.3 GO:0008466 glycogenin glucosyltransferase activity(GO:0008466)
0.1 1.9 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.1 1.7 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.1 0.8 GO:0043225 anion transmembrane-transporting ATPase activity(GO:0043225)
0.1 11.6 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.1 0.4 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.1 8.3 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.1 1.2 GO:0045504 dynein heavy chain binding(GO:0045504)
0.1 0.3 GO:0008798 beta-aspartyl-peptidase activity(GO:0008798)
0.1 3.4 GO:0050699 WW domain binding(GO:0050699)
0.1 1.8 GO:0004029 aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.1 1.0 GO:0000150 recombinase activity(GO:0000150)
0.0 4.4 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.3 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.6 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.0 1.7 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 1.3 GO:0005328 neurotransmitter:sodium symporter activity(GO:0005328)
0.0 0.7 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 1.3 GO:0005112 Notch binding(GO:0005112)
0.0 13.8 GO:0000287 magnesium ion binding(GO:0000287)
0.0 5.6 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 4.4 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.0 2.2 GO:0051018 protein kinase A binding(GO:0051018)
0.0 3.2 GO:0017022 myosin binding(GO:0017022)
0.0 3.9 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 1.4 GO:0001972 retinoic acid binding(GO:0001972)
0.0 2.0 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.8 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 0.3 GO:0015181 arginine transmembrane transporter activity(GO:0015181)
0.0 11.6 GO:0060090 binding, bridging(GO:0060090)
0.0 9.8 GO:0051015 actin filament binding(GO:0051015)
0.0 0.2 GO:0003923 GPI-anchor transamidase activity(GO:0003923)
0.0 1.7 GO:0032452 histone demethylase activity(GO:0032452)
0.0 4.4 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 5.5 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.0 1.5 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.0 0.6 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 0.9 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
0.0 0.4 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.0 0.9 GO:0003682 chromatin binding(GO:0003682)
0.0 0.4 GO:0015250 water channel activity(GO:0015250)
0.0 0.6 GO:0046914 transition metal ion binding(GO:0046914)
0.0 0.3 GO:0022889 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0 0.8 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 1.0 GO:0030544 Hsp70 protein binding(GO:0030544)
0.0 0.2 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.0 4.1 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 5.1 GO:0035091 phosphatidylinositol binding(GO:0035091)
0.0 1.4 GO:0005518 collagen binding(GO:0005518)
0.0 1.7 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 2.1 GO:0019903 protein phosphatase binding(GO:0019903)
0.0 0.1 GO:0035197 siRNA binding(GO:0035197)
0.0 1.7 GO:0016779 nucleotidyltransferase activity(GO:0016779)
0.0 4.8 GO:0003723 RNA binding(GO:0003723)
0.0 1.6 GO:0001046 core promoter sequence-specific DNA binding(GO:0001046)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 49.7 NABA COLLAGENS Genes encoding collagen proteins
0.7 27.2 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.3 8.5 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.3 31.5 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.1 10.2 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.1 6.2 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.1 8.4 PID NCADHERIN PATHWAY N-cadherin signaling events
0.1 8.9 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.1 2.7 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.1 7.5 PID RAS PATHWAY Regulation of Ras family activation
0.1 5.1 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.1 0.7 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.1 4.3 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.1 1.9 PID NETRIN PATHWAY Netrin-mediated signaling events
0.1 3.1 PID EPHB FWD PATHWAY EPHB forward signaling
0.1 4.8 PID FOXO PATHWAY FoxO family signaling
0.1 1.4 PID AVB3 OPN PATHWAY Osteopontin-mediated events
0.1 6.8 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.1 3.9 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.1 1.3 PID RAC1 PATHWAY RAC1 signaling pathway
0.1 2.0 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.1 6.0 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.1 3.7 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 5.3 PID E2F PATHWAY E2F transcription factor network
0.0 12.2 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 1.3 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.9 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 1.6 PID BCR 5PATHWAY BCR signaling pathway
0.0 2.0 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 1.3 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 1.5 PID AURORA A PATHWAY Aurora A signaling
0.0 2.3 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 1.2 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.0 1.1 PID MTOR 4PATHWAY mTOR signaling pathway
0.0 1.2 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0 0.9 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 14.1 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.6 49.9 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.4 9.4 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.3 3.2 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.2 10.2 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.2 6.7 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.2 4.2 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.2 1.5 REACTOME TRAF6 MEDIATED INDUCTION OF TAK1 COMPLEX Genes involved in TRAF6 mediated induction of TAK1 complex
0.1 23.9 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.1 6.8 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.1 2.3 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.1 4.0 REACTOME PHOSPHORYLATION OF THE APC C Genes involved in Phosphorylation of the APC/C
0.1 4.7 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.1 2.3 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.1 2.2 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.1 6.9 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.1 8.4 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.1 3.2 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.1 2.6 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.1 2.3 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.1 1.4 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.1 0.9 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.1 0.8 REACTOME ADP SIGNALLING THROUGH P2RY1 Genes involved in ADP signalling through P2Y purinoceptor 1
0.1 1.6 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.1 1.4 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.1 5.7 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.1 1.7 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.1 1.3 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.1 1.3 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.1 1.4 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
0.0 2.7 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 2.5 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.0 2.5 REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
0.0 4.3 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 2.6 REACTOME INWARDLY RECTIFYING K CHANNELS Genes involved in Inwardly rectifying K+ channels
0.0 1.9 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 1.3 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0 1.7 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 0.4 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 1.7 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.0 3.7 REACTOME CELL JUNCTION ORGANIZATION Genes involved in Cell junction organization
0.0 0.9 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 1.3 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.7 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.1 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0 0.3 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 0.4 REACTOME ACYL CHAIN REMODELLING OF PE Genes involved in Acyl chain remodelling of PE
0.0 0.4 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 0.2 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.0 1.1 REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds