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SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for HOXB7

Z-value: 0.75

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Transcription factors associated with HOXB7

Gene Symbol Gene ID Gene Info
HOXB7
ENSG00000260027.3 homeobox B7

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HOXB7hg19_v2_chr17_-_46688334_46688385-0.957.1e-11Click!

Activity profile of HOXB7 motif

Sorted Z-values of HOXB7 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr20_-_1309809 4.99 ENST00000360779.3
SDCBP2
syndecan binding protein (syntenin) 2
chr3_+_189349162 3.59 ENST00000264731.3
ENST00000382063.4
ENST00000418709.2
ENST00000320472.5
ENST00000392460.3
ENST00000440651.2
TP63
tumor protein p63
chr18_+_21464737 3.26 ENST00000586751.1
LAMA3
laminin, alpha 3
chr11_+_57365150 3.21 ENST00000457869.1
ENST00000340687.6
ENST00000378323.4
ENST00000378324.2
ENST00000403558.1
SERPING1
serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
chr18_+_61554932 3.19 ENST00000299502.4
ENST00000457692.1
ENST00000413956.1
SERPINB2
serpin peptidase inhibitor, clade B (ovalbumin), member 2
chr12_-_28124903 3.18 ENST00000395872.1
ENST00000354417.3
ENST00000201015.4
PTHLH
parathyroid hormone-like hormone
chr2_+_169926047 3.09 ENST00000428522.1
ENST00000450153.1
ENST00000421653.1
DHRS9
dehydrogenase/reductase (SDR family) member 9
chr12_-_28125638 3.06 ENST00000545234.1
PTHLH
parathyroid hormone-like hormone
chr10_-_5660118 2.64 ENST00000427341.1
RP11-336A10.4
RP11-336A10.4
chr10_+_51549498 2.59 ENST00000358559.2
ENST00000298239.6
MSMB
microseminoprotein, beta-
chr16_+_82660560 2.42 ENST00000268613.10
ENST00000565636.1
ENST00000431540.3
ENST00000428848.3
CDH13
cadherin 13
chr4_+_100737954 2.37 ENST00000296414.7
ENST00000512369.1
DAPP1
dual adaptor of phosphotyrosine and 3-phosphoinositides
chr12_-_15104040 2.35 ENST00000541644.1
ENST00000545895.1
ARHGDIB
Rho GDP dissociation inhibitor (GDI) beta
chr4_+_71384300 2.27 ENST00000504451.1
AMTN
amelotin
chr1_-_209957882 2.24 ENST00000294811.1
C1orf74
chromosome 1 open reading frame 74
chr3_+_189507460 2.23 ENST00000434928.1
TP63
tumor protein p63
chr2_+_234104079 2.16 ENST00000417661.1
INPP5D
inositol polyphosphate-5-phosphatase, 145kDa
chr11_+_35222629 2.07 ENST00000526553.1
CD44
CD44 molecule (Indian blood group)
chr3_+_189507523 2.06 ENST00000437221.1
ENST00000392463.2
ENST00000392461.3
ENST00000449992.1
ENST00000456148.1
TP63
tumor protein p63
chr4_+_71384257 2.01 ENST00000339336.4
AMTN
amelotin
chr11_-_102668879 1.80 ENST00000315274.6
MMP1
matrix metallopeptidase 1 (interstitial collagenase)
chr19_-_20748541 1.78 ENST00000427401.4
ENST00000594419.1
ZNF737
zinc finger protein 737
chr9_-_73029540 1.77 ENST00000377126.2
KLF9
Kruppel-like factor 9
chr2_-_56150910 1.70 ENST00000424836.2
ENST00000438672.1
ENST00000440439.1
ENST00000429909.1
ENST00000424207.1
ENST00000452337.1
ENST00000355426.3
ENST00000439193.1
ENST00000421664.1
EFEMP1
EGF containing fibulin-like extracellular matrix protein 1
chr3_+_189507432 1.67 ENST00000354600.5
TP63
tumor protein p63
chr6_+_130339710 1.64 ENST00000526087.1
ENST00000533560.1
ENST00000361794.2
L3MBTL3
l(3)mbt-like 3 (Drosophila)
chr19_-_20748614 1.52 ENST00000596797.1
ZNF737
zinc finger protein 737
chr4_+_26324474 1.51 ENST00000514675.1
RBPJ
recombination signal binding protein for immunoglobulin kappa J region
chr11_-_57194948 1.48 ENST00000533235.1
ENST00000526621.1
ENST00000352187.1
SLC43A3
solute carrier family 43, member 3
chr10_+_5488564 1.38 ENST00000449083.1
ENST00000380359.3
NET1
neuroepithelial cell transforming 1
chr19_-_52598958 1.38 ENST00000594440.1
ENST00000426391.2
ENST00000389534.4
ZNF841
zinc finger protein 841
chr1_+_205473720 1.34 ENST00000429964.2
ENST00000506784.1
ENST00000360066.2
CDK18
cyclin-dependent kinase 18
chr11_-_8795787 1.33 ENST00000528196.1
ENST00000533681.1
ST5
suppression of tumorigenicity 5
chr1_+_152956549 1.30 ENST00000307122.2
SPRR1A
small proline-rich protein 1A
chr12_+_56324756 1.29 ENST00000331886.5
ENST00000555090.1
DGKA
diacylglycerol kinase, alpha 80kDa
chr14_+_51955831 1.29 ENST00000356218.4
FRMD6
FERM domain containing 6
chr1_+_101702417 1.29 ENST00000305352.6
S1PR1
sphingosine-1-phosphate receptor 1
chr10_+_13141585 1.25 ENST00000378764.2
OPTN
optineurin
chr14_-_23624511 1.24 ENST00000529705.2
SLC7A8
solute carrier family 7 (amino acid transporter light chain, L system), member 8
chr2_-_70780770 1.22 ENST00000444975.1
ENST00000445399.1
ENST00000418333.2
TGFA
transforming growth factor, alpha
chr7_+_20370746 1.21 ENST00000222573.4
ITGB8
integrin, beta 8
chr15_+_49715449 1.20 ENST00000560979.1
FGF7
fibroblast growth factor 7
chr19_-_51512804 1.20 ENST00000594211.1
ENST00000376832.4
KLK9
kallikrein-related peptidase 9
chr2_-_230787879 1.20 ENST00000435716.1
TRIP12
thyroid hormone receptor interactor 12
chr6_-_113953705 1.18 ENST00000452675.1
RP11-367G18.1
RP11-367G18.1
chr11_-_57194817 1.15 ENST00000529748.1
ENST00000525474.1
SLC43A3
solute carrier family 43, member 3
chr16_-_65106110 1.12 ENST00000562882.1
ENST00000567934.1
CDH11
cadherin 11, type 2, OB-cadherin (osteoblast)
chr10_+_24755416 1.11 ENST00000396446.1
ENST00000396445.1
ENST00000376451.2
KIAA1217
KIAA1217
chr19_+_12203069 1.10 ENST00000430298.2
ENST00000339302.4
ZNF788
ZNF788
zinc finger family member 788
Zinc finger protein 788
chr15_-_93616340 1.07 ENST00000557420.1
ENST00000542321.2
RGMA
repulsive guidance molecule family member a
chr19_+_13135386 1.06 ENST00000360105.4
ENST00000588228.1
ENST00000591028.1
NFIX
nuclear factor I/X (CCAAT-binding transcription factor)
chr4_+_144354644 1.05 ENST00000512843.1
GAB1
GRB2-associated binding protein 1
chr10_+_13142075 1.04 ENST00000378757.2
ENST00000430081.1
ENST00000378752.3
ENST00000378748.3
OPTN
optineurin
chr13_-_41240717 1.03 ENST00000379561.5
FOXO1
forkhead box O1
chr5_+_125695805 1.02 ENST00000513040.1
GRAMD3
GRAM domain containing 3
chr10_+_13142225 1.00 ENST00000378747.3
OPTN
optineurin
chr12_+_56324933 0.99 ENST00000549629.1
ENST00000555218.1
DGKA
diacylglycerol kinase, alpha 80kDa
chr4_+_71600063 0.99 ENST00000513597.1
RUFY3
RUN and FYVE domain containing 3
chr3_+_101659682 0.98 ENST00000465215.1
RP11-221J22.1
RP11-221J22.1
chr15_+_84904525 0.97 ENST00000510439.2
GOLGA6L4
golgin A6 family-like 4
chr10_+_13141441 0.97 ENST00000263036.5
OPTN
optineurin
chr20_+_36531499 0.97 ENST00000373458.3
ENST00000373461.4
ENST00000373459.4
VSTM2L
V-set and transmembrane domain containing 2 like
chr4_+_26323764 0.97 ENST00000514730.1
ENST00000507574.1
RBPJ
recombination signal binding protein for immunoglobulin kappa J region
chr17_+_7758374 0.95 ENST00000301599.6
ENST00000574668.1
TMEM88
transmembrane protein 88
chr2_+_234600253 0.94 ENST00000373424.1
ENST00000441351.1
UGT1A6
UDP glucuronosyltransferase 1 family, polypeptide A6
chr12_-_22063787 0.94 ENST00000544039.1
ABCC9
ATP-binding cassette, sub-family C (CFTR/MRP), member 9
chr4_+_169013666 0.94 ENST00000359299.3
ANXA10
annexin A10
chr16_+_21623958 0.94 ENST00000568826.1
METTL9
methyltransferase like 9
chr8_-_42360015 0.94 ENST00000522707.1
SLC20A2
solute carrier family 20 (phosphate transporter), member 2
chr12_-_91546926 0.94 ENST00000550758.1
DCN
decorin
chr16_+_82660635 0.92 ENST00000567445.1
ENST00000446376.2
CDH13
cadherin 13
chr10_-_98273668 0.91 ENST00000357947.3
TLL2
tolloid-like 2
chr6_+_45390222 0.90 ENST00000359524.5
RUNX2
runt-related transcription factor 2
chr4_-_102267953 0.89 ENST00000523694.2
ENST00000507176.1
PPP3CA
protein phosphatase 3, catalytic subunit, alpha isozyme
chr11_+_18154059 0.89 ENST00000531264.1
MRGPRX3
MAS-related GPR, member X3
chr19_+_49199209 0.88 ENST00000522966.1
ENST00000425340.2
ENST00000391876.4
FUT2
fucosyltransferase 2 (secretor status included)
chr15_-_93616892 0.88 ENST00000556658.1
ENST00000538818.1
ENST00000425933.2
RGMA
repulsive guidance molecule family member a
chr2_+_102413726 0.87 ENST00000350878.4
MAP4K4
mitogen-activated protein kinase kinase kinase kinase 4
chr15_-_99057551 0.84 ENST00000558256.1
FAM169B
family with sequence similarity 169, member B
chr12_+_40787194 0.84 ENST00000425730.2
ENST00000454784.4
MUC19
mucin 19, oligomeric
chr6_-_138833630 0.84 ENST00000533765.1
NHSL1
NHS-like 1
chr8_-_130799134 0.84 ENST00000276708.4
GSDMC
gasdermin C
chr1_-_91487806 0.83 ENST00000361321.5
ZNF644
zinc finger protein 644
chr11_-_67981046 0.83 ENST00000402789.1
ENST00000402185.2
ENST00000458496.1
SUV420H1
suppressor of variegation 4-20 homolog 1 (Drosophila)
chr9_-_27529726 0.82 ENST00000262244.5
MOB3B
MOB kinase activator 3B
chr15_+_83098710 0.81 ENST00000561062.1
ENST00000358583.3
GOLGA6L9
golgin A6 family-like 20
chr17_+_61151306 0.79 ENST00000580068.1
ENST00000580466.1
TANC2
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
chr8_-_116681123 0.79 ENST00000519674.1
TRPS1
trichorhinophalangeal syndrome I
chr8_-_116681221 0.79 ENST00000395715.3
TRPS1
trichorhinophalangeal syndrome I
chr3_-_55539287 0.79 ENST00000472238.1
RP11-875H7.5
RP11-875H7.5
chr5_+_125758865 0.78 ENST00000542322.1
ENST00000544396.1
GRAMD3
GRAM domain containing 3
chr1_-_91487770 0.76 ENST00000337393.5
ZNF644
zinc finger protein 644
chr15_-_82641706 0.76 ENST00000439287.4
GOLGA6L10
golgin A6 family-like 10
chr22_+_25465786 0.75 ENST00000401395.1
KIAA1671
KIAA1671
chr5_-_132073111 0.75 ENST00000403231.1
KIF3A
kinesin family member 3A
chr2_-_151344172 0.74 ENST00000375734.2
ENST00000263895.4
ENST00000454202.1
RND3
Rho family GTPase 3
chr4_+_71600144 0.74 ENST00000502653.1
RUFY3
RUN and FYVE domain containing 3
chr4_-_48014931 0.74 ENST00000420489.2
ENST00000504722.1
CNGA1
cyclic nucleotide gated channel alpha 1
chr10_+_90484301 0.73 ENST00000404190.1
LIPK
lipase, family member K
chr5_+_125758813 0.73 ENST00000285689.3
ENST00000515200.1
GRAMD3
GRAM domain containing 3
chr1_-_9953295 0.72 ENST00000377258.1
CTNNBIP1
catenin, beta interacting protein 1
chr3_+_181429704 0.72 ENST00000431565.2
ENST00000325404.1
SOX2
SRY (sex determining region Y)-box 2
chr2_+_63277927 0.72 ENST00000282549.2
OTX1
orthodenticle homeobox 1
chr13_-_46756351 0.71 ENST00000323076.2
LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr14_+_55034599 0.70 ENST00000392067.3
ENST00000357634.3
SAMD4A
sterile alpha motif domain containing 4A
chr21_-_33984456 0.70 ENST00000431216.1
ENST00000553001.1
ENST00000440966.1
AP000275.65
C21orf59
Uncharacterized protein
chromosome 21 open reading frame 59
chr12_-_118628350 0.69 ENST00000537952.1
ENST00000537822.1
TAOK3
TAO kinase 3
chr3_+_193853927 0.68 ENST00000232424.3
HES1
hes family bHLH transcription factor 1
chr5_-_171881362 0.68 ENST00000519643.1
SH3PXD2B
SH3 and PX domains 2B
chr2_-_208030295 0.68 ENST00000458272.1
KLF7
Kruppel-like factor 7 (ubiquitous)
chr4_+_74301880 0.68 ENST00000395792.2
ENST00000226359.2
AFP
alpha-fetoprotein
chr4_+_148653206 0.68 ENST00000336498.3
ARHGAP10
Rho GTPase activating protein 10
chr8_-_116680833 0.68 ENST00000220888.5
TRPS1
trichorhinophalangeal syndrome I
chr5_+_131409476 0.68 ENST00000296871.2
CSF2
colony stimulating factor 2 (granulocyte-macrophage)
chr3_-_183145873 0.67 ENST00000447025.2
ENST00000414362.2
ENST00000328913.3
MCF2L2
MCF.2 cell line derived transforming sequence-like 2
chr3_+_101818088 0.67 ENST00000491959.1
ZPLD1
zona pellucida-like domain containing 1
chrM_+_10053 0.67 ENST00000361227.2
MT-ND3
mitochondrially encoded NADH dehydrogenase 3
chr15_+_82722225 0.67 ENST00000300515.8
GOLGA6L9
golgin A6 family-like 9
chr3_-_47932759 0.65 ENST00000441748.2
ENST00000335271.5
MAP4
microtubule-associated protein 4
chr6_+_144904334 0.65 ENST00000367526.4
UTRN
utrophin
chr14_+_101295638 0.64 ENST00000523671.2
MEG3
maternally expressed 3 (non-protein coding)
chr1_+_117963209 0.64 ENST00000449370.2
MAN1A2
mannosidase, alpha, class 1A, member 2
chr1_+_12524965 0.63 ENST00000471923.1
VPS13D
vacuolar protein sorting 13 homolog D (S. cerevisiae)
chr5_+_125759140 0.62 ENST00000543198.1
GRAMD3
GRAM domain containing 3
chr10_+_63661053 0.62 ENST00000279873.7
ARID5B
AT rich interactive domain 5B (MRF1-like)
chr2_+_192141611 0.61 ENST00000392316.1
MYO1B
myosin IB
chr3_-_142166846 0.60 ENST00000463916.1
ENST00000544157.1
XRN1
5'-3' exoribonuclease 1
chr10_-_62332357 0.60 ENST00000503366.1
ANK3
ankyrin 3, node of Ranvier (ankyrin G)
chr11_-_2162162 0.59 ENST00000381389.1
IGF2
insulin-like growth factor 2 (somatomedin A)
chr19_+_13134772 0.59 ENST00000587760.1
ENST00000585575.1
NFIX
nuclear factor I/X (CCAAT-binding transcription factor)
chr3_-_71114066 0.59 ENST00000485326.2
FOXP1
forkhead box P1
chr8_+_104892639 0.59 ENST00000436393.2
RIMS2
regulating synaptic membrane exocytosis 2
chr2_+_171036635 0.57 ENST00000484338.2
ENST00000334231.6
MYO3B
myosin IIIB
chr22_-_22337154 0.57 ENST00000413067.2
ENST00000437929.1
ENST00000456075.1
ENST00000434517.1
ENST00000424393.1
ENST00000449704.1
ENST00000437103.1
TOP3B
topoisomerase (DNA) III beta
chr11_+_6947647 0.57 ENST00000278319.5
ZNF215
zinc finger protein 215
chr7_+_30185496 0.57 ENST00000455738.1
C7orf41
maturin, neural progenitor differentiation regulator homolog (Xenopus)
chr2_-_207078154 0.57 ENST00000447845.1
GPR1
G protein-coupled receptor 1
chr1_-_104238912 0.56 ENST00000330330.5
AMY1B
amylase, alpha 1B (salivary)
chr10_+_102891048 0.56 ENST00000467928.2
TLX1
T-cell leukemia homeobox 1
chr5_-_125930929 0.56 ENST00000553117.1
ENST00000447989.2
ENST00000409134.3
ALDH7A1
aldehyde dehydrogenase 7 family, member A1
chr19_+_12203100 0.56 ENST00000596883.1
ZNF788
zinc finger family member 788
chr3_+_136581042 0.55 ENST00000288986.2
ENST00000481752.1
ENST00000491539.1
ENST00000485096.1
NCK1
NCK adaptor protein 1
chr2_-_207078086 0.55 ENST00000442134.1
GPR1
G protein-coupled receptor 1
chr22_-_36761081 0.54 ENST00000456729.1
ENST00000401701.1
MYH9
myosin, heavy chain 9, non-muscle
chr1_-_104239076 0.54 ENST00000370080.3
AMY1B
amylase, alpha 1B (salivary)
chr13_-_103719196 0.54 ENST00000245312.3
SLC10A2
solute carrier family 10 (sodium/bile acid cotransporter), member 2
chr2_+_201242715 0.54 ENST00000421573.1
SPATS2L
spermatogenesis associated, serine-rich 2-like
chr12_+_65996599 0.54 ENST00000539116.1
ENST00000541391.1
RP11-221N13.3
RP11-221N13.3
chr3_+_154741907 0.53 ENST00000492661.1
MME
membrane metallo-endopeptidase
chr1_+_16084428 0.52 ENST00000510929.1
ENST00000502638.1
FBLIM1
filamin binding LIM protein 1
chr17_-_39728303 0.52 ENST00000588431.1
ENST00000246662.4
KRT9
keratin 9
chr12_+_96252706 0.50 ENST00000266735.5
ENST00000553192.1
ENST00000552085.1
SNRPF
small nuclear ribonucleoprotein polypeptide F
chr6_+_42584847 0.50 ENST00000372883.3
UBR2
ubiquitin protein ligase E3 component n-recognin 2
chr4_-_72649763 0.50 ENST00000513476.1
GC
group-specific component (vitamin D binding protein)
chr12_+_123944070 0.49 ENST00000412157.2
SNRNP35
small nuclear ribonucleoprotein 35kDa (U11/U12)
chr20_+_52105495 0.49 ENST00000439873.2
AL354993.1
Cell growth-inhibiting protein 7; HCG1784586; Uncharacterized protein
chr10_+_47894572 0.49 ENST00000355876.5
FAM21B
family with sequence similarity 21, member B
chr1_+_196621002 0.48 ENST00000367429.4
ENST00000439155.2
CFH
complement factor H
chr11_-_104893863 0.48 ENST00000260315.3
ENST00000526056.1
ENST00000531367.1
ENST00000456094.1
ENST00000444749.2
ENST00000393141.2
ENST00000418434.1
ENST00000393139.2
CASP5
caspase 5, apoptosis-related cysteine peptidase
chr3_+_157827841 0.48 ENST00000295930.3
ENST00000471994.1
ENST00000464171.1
ENST00000312179.6
ENST00000475278.2
RSRC1
arginine/serine-rich coiled-coil 1
chr5_-_125930877 0.48 ENST00000510111.2
ENST00000509270.1
ALDH7A1
aldehyde dehydrogenase 7 family, member A1
chr14_-_74417096 0.48 ENST00000286544.3
FAM161B
family with sequence similarity 161, member B
chr14_+_24584056 0.47 ENST00000561001.1
DCAF11
DDB1 and CUL4 associated factor 11
chr3_+_177545563 0.47 ENST00000434309.1
RP11-91K9.1
RP11-91K9.1
chr15_-_42343388 0.47 ENST00000399518.3
PLA2G4E
phospholipase A2, group IVE
chr11_+_28724129 0.46 ENST00000513853.1
RP11-115J23.1
RP11-115J23.1
chr19_+_41698927 0.45 ENST00000310054.4
CYP2S1
cytochrome P450, family 2, subfamily S, polypeptide 1
chrX_-_77225135 0.45 ENST00000458128.1
PGAM4
phosphoglycerate mutase family member 4
chr8_-_6115044 0.45 ENST00000519555.1
RP11-124B13.1
RP11-124B13.1
chr19_+_44645700 0.45 ENST00000592437.1
ZNF234
zinc finger protein 234
chr6_-_32157947 0.44 ENST00000375050.4
PBX2
pre-B-cell leukemia homeobox 2
chr6_+_90272027 0.44 ENST00000522441.1
ANKRD6
ankyrin repeat domain 6
chr7_+_30185406 0.44 ENST00000324489.5
C7orf41
maturin, neural progenitor differentiation regulator homolog (Xenopus)
chr5_-_132073210 0.43 ENST00000378735.1
ENST00000378746.4
KIF3A
kinesin family member 3A
chr1_+_104198377 0.43 ENST00000370083.4
AMY1A
amylase, alpha 1A (salivary)
chr21_+_44313375 0.43 ENST00000354250.2
ENST00000340344.4
NDUFV3
NADH dehydrogenase (ubiquinone) flavoprotein 3, 10kDa
chr7_+_117824210 0.42 ENST00000422760.1
ENST00000411938.1
NAA38
N(alpha)-acetyltransferase 38, NatC auxiliary subunit
chr11_+_44117219 0.42 ENST00000532479.1
ENST00000527014.1
EXT2
exostosin glycosyltransferase 2
chr1_-_31538517 0.42 ENST00000440538.2
ENST00000423018.2
ENST00000424085.2
ENST00000426105.2
ENST00000257075.5
ENST00000373747.3
ENST00000525843.1
ENST00000373742.2
PUM1
pumilio RNA-binding family member 1
chr12_-_67197760 0.42 ENST00000539540.1
ENST00000540433.1
ENST00000541947.1
ENST00000538373.1
GRIP1
glutamate receptor interacting protein 1
chr5_-_179047881 0.41 ENST00000521173.1
HNRNPH1
heterogeneous nuclear ribonucleoprotein H1 (H)
chr11_+_128563652 0.41 ENST00000527786.2
FLI1
Fli-1 proto-oncogene, ETS transcription factor
chr17_+_41363854 0.41 ENST00000588693.1
ENST00000588659.1
ENST00000541594.1
ENST00000536052.1
ENST00000331615.3
TMEM106A
transmembrane protein 106A
chr1_-_28241024 0.41 ENST00000313433.7
ENST00000444045.1
RPA2
replication protein A2, 32kDa
chr1_-_147610081 0.40 ENST00000369226.3
NBPF24
neuroblastoma breakpoint family, member 24
chr17_+_45973516 0.40 ENST00000376741.4
SP2
Sp2 transcription factor
chr21_+_43619796 0.39 ENST00000398457.2
ABCG1
ATP-binding cassette, sub-family G (WHITE), member 1
chr3_+_111393659 0.39 ENST00000477665.1
PLCXD2
phosphatidylinositol-specific phospholipase C, X domain containing 2
chr8_-_37411648 0.39 ENST00000519738.1
RP11-150O12.1
RP11-150O12.1
chr14_+_62229075 0.39 ENST00000216294.4
SNAPC1
small nuclear RNA activating complex, polypeptide 1, 43kDa
chr4_-_69215467 0.39 ENST00000579690.1
YTHDC1
YTH domain containing 1
chr1_+_19923454 0.39 ENST00000602662.1
ENST00000602293.1
ENST00000322753.6
MINOS1-NBL1
MINOS1
MINOS1-NBL1 readthrough
mitochondrial inner membrane organizing system 1
chr2_+_234621551 0.38 ENST00000608381.1
ENST00000373414.3
UGT1A1
UGT1A5
UDP glucuronosyltransferase 1 family, polypeptide A8
UDP glucuronosyltransferase 1 family, polypeptide A5
chr19_+_37837185 0.38 ENST00000541583.2
HKR1
HKR1, GLI-Kruppel zinc finger family member
chr11_-_57194919 0.38 ENST00000532795.1
SLC43A3
solute carrier family 43, member 3
chr7_-_86595190 0.37 ENST00000398276.2
ENST00000416314.1
ENST00000425689.1
KIAA1324L
KIAA1324-like
chr4_-_69434245 0.37 ENST00000317746.2
UGT2B17
UDP glucuronosyltransferase 2 family, polypeptide B17
chr15_-_60683326 0.37 ENST00000559350.1
ENST00000558986.1
ENST00000560389.1
ANXA2
annexin A2
chr2_+_234637754 0.37 ENST00000482026.1
ENST00000609767.1
UGT1A3
UGT1A1
UDP glucuronosyltransferase 1 family, polypeptide A3
UDP glucuronosyltransferase 1 family, polypeptide A8
chr12_-_92821922 0.37 ENST00000538965.1
ENST00000378487.2
CLLU1OS
chronic lymphocytic leukemia up-regulated 1 opposite strand

Network of associatons between targets according to the STRING database.

First level regulatory network of HOXB7

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
2.4 9.6 GO:0007499 ectoderm and mesoderm interaction(GO:0007499)
1.4 4.3 GO:0070175 positive regulation of enamel mineralization(GO:0070175)
0.5 4.3 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.4 2.2 GO:0045658 regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
0.4 1.3 GO:0003245 cardiac muscle tissue growth involved in heart morphogenesis(GO:0003245)
0.3 2.3 GO:0071461 cellular response to redox state(GO:0071461)
0.3 2.5 GO:1901189 positive regulation of ephrin receptor signaling pathway(GO:1901189) positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068)
0.3 3.2 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.3 3.1 GO:0042905 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.3 0.8 GO:1903674 regulation of cap-dependent translational initiation(GO:1903674) positive regulation of cap-dependent translational initiation(GO:1903676)
0.3 1.0 GO:0031456 glycine betaine biosynthetic process from choline(GO:0019285) glycine betaine metabolic process(GO:0031455) glycine betaine biosynthetic process(GO:0031456)
0.3 1.8 GO:0051414 response to cortisol(GO:0051414)
0.2 3.3 GO:0055096 lipoprotein particle mediated signaling(GO:0055095) low-density lipoprotein particle mediated signaling(GO:0055096)
0.2 2.1 GO:1900625 regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.2 0.7 GO:0042668 auditory receptor cell fate determination(GO:0042668) negative regulation of auditory receptor cell differentiation(GO:0045608) regulation of timing of neuron differentiation(GO:0060164) negative regulation of pro-B cell differentiation(GO:2000974)
0.2 0.9 GO:0048631 regulation of skeletal muscle tissue growth(GO:0048631)
0.2 0.7 GO:0032747 positive regulation of interleukin-23 production(GO:0032747)
0.2 0.2 GO:0070585 protein localization to mitochondrion(GO:0070585)
0.2 0.9 GO:1905205 positive regulation of connective tissue replacement(GO:1905205)
0.2 7.2 GO:0032331 negative regulation of chondrocyte differentiation(GO:0032331)
0.2 1.0 GO:0035947 regulation of gluconeogenesis by regulation of transcription from RNA polymerase II promoter(GO:0035947)
0.2 1.0 GO:0060437 lung growth(GO:0060437)
0.1 0.7 GO:0002528 regulation of vascular permeability involved in acute inflammatory response(GO:0002528)
0.1 1.3 GO:0003383 apical constriction(GO:0003383)
0.1 0.4 GO:0055099 response to high density lipoprotein particle(GO:0055099)
0.1 1.1 GO:0048706 embryonic skeletal system development(GO:0048706)
0.1 1.6 GO:0002051 osteoblast fate commitment(GO:0002051)
0.1 1.2 GO:0033183 negative regulation of histone ubiquitination(GO:0033183) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315)
0.1 0.5 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
0.1 0.6 GO:0071409 cellular response to cycloheximide(GO:0071409)
0.1 1.6 GO:0043249 erythrocyte maturation(GO:0043249)
0.1 0.5 GO:0032796 uropod organization(GO:0032796)
0.1 0.7 GO:0048852 diencephalon morphogenesis(GO:0048852)
0.1 0.6 GO:1900827 maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.1 0.5 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.1 0.6 GO:0032625 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.1 0.4 GO:0042796 snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.1 0.3 GO:0072356 chromosome passenger complex localization to kinetochore(GO:0072356)
0.1 0.7 GO:0051012 microtubule sliding(GO:0051012)
0.1 0.4 GO:0052227 multi-organism catabolic process(GO:0044035) development of symbiont involved in interaction with host(GO:0044115) modulation of development of symbiont involved in interaction with host(GO:0044145) negative regulation of development of symbiont involved in interaction with host(GO:0044147) metabolism of substance in other organism involved in symbiotic interaction(GO:0052214) catabolism of substance in other organism involved in symbiotic interaction(GO:0052227) metabolism of macromolecule in other organism involved in symbiotic interaction(GO:0052229) catabolism by host of symbiont macromolecule(GO:0052360) catabolism by organism of macromolecule in other organism involved in symbiotic interaction(GO:0052361) catabolism by host of symbiont protein(GO:0052362) catabolism by organism of protein in other organism involved in symbiotic interaction(GO:0052363) catabolism by host of substance in symbiont(GO:0052364) metabolism by host of symbiont macromolecule(GO:0052416) metabolism by host of symbiont protein(GO:0052417) metabolism by organism of protein in other organism involved in symbiotic interaction(GO:0052418) metabolism by host of substance in symbiont(GO:0052419)
0.1 0.6 GO:1904381 Golgi apparatus mannose trimming(GO:1904381)
0.1 3.3 GO:0031581 hemidesmosome assembly(GO:0031581)
0.1 0.2 GO:0070173 regulation of enamel mineralization(GO:0070173)
0.1 0.3 GO:0006419 alanyl-tRNA aminoacylation(GO:0006419)
0.1 1.2 GO:0072383 plus-end-directed vesicle transport along microtubule(GO:0072383)
0.1 0.2 GO:1903033 regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033)
0.1 1.4 GO:0051451 myoblast migration(GO:0051451)
0.1 0.3 GO:0050902 leukocyte adhesive activation(GO:0050902)
0.1 1.9 GO:0048681 negative regulation of axon regeneration(GO:0048681)
0.1 2.3 GO:0046339 diacylglycerol metabolic process(GO:0046339)
0.1 0.5 GO:0044026 DNA hypermethylation(GO:0044026)
0.1 0.4 GO:0006789 bilirubin conjugation(GO:0006789)
0.1 0.7 GO:0001714 endodermal cell fate specification(GO:0001714)
0.1 0.3 GO:0052405 negative regulation by host of symbiont molecular function(GO:0052405)
0.1 0.6 GO:2000467 positive regulation of glycogen (starch) synthase activity(GO:2000467)
0.1 0.9 GO:0042355 fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355)
0.1 1.0 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.1 0.6 GO:1990253 cellular response to leucine starvation(GO:1990253)
0.1 0.9 GO:0021957 corticospinal tract morphogenesis(GO:0021957)
0.1 0.5 GO:0035234 ectopic germ cell programmed cell death(GO:0035234)
0.1 0.5 GO:0071492 cellular response to UV-A(GO:0071492)
0.1 1.0 GO:0045741 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741)
0.1 0.3 GO:0046092 deoxycytidine metabolic process(GO:0046092)
0.1 0.8 GO:0097475 motor neuron migration(GO:0097475)
0.1 0.9 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.1 2.6 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 0.2 GO:2001045 negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.0 0.6 GO:0061669 spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.0 0.3 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.0 0.1 GO:0006147 guanine catabolic process(GO:0006147)
0.0 0.2 GO:0008050 female courtship behavior(GO:0008050)
0.0 1.0 GO:0006265 DNA topological change(GO:0006265)
0.0 0.4 GO:0060449 bud elongation involved in lung branching(GO:0060449)
0.0 0.2 GO:0006127 glycerophosphate shuttle(GO:0006127)
0.0 0.2 GO:0036269 swimming behavior(GO:0036269)
0.0 1.8 GO:0032461 positive regulation of protein oligomerization(GO:0032461)
0.0 0.3 GO:1901475 pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475)
0.0 0.1 GO:1903774 positive regulation of viral budding via host ESCRT complex(GO:1903774)
0.0 3.9 GO:0071349 interleukin-12-mediated signaling pathway(GO:0035722) cellular response to interleukin-12(GO:0071349)
0.0 0.6 GO:0014877 response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.0 0.1 GO:1904046 negative regulation of vascular endothelial growth factor production(GO:1904046)
0.0 0.3 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.0 0.2 GO:0035553 oxidative RNA demethylation(GO:0035513) oxidative single-stranded RNA demethylation(GO:0035553)
0.0 0.7 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.0 1.7 GO:2000114 regulation of establishment of cell polarity(GO:2000114)
0.0 0.4 GO:1900246 positive regulation of RIG-I signaling pathway(GO:1900246)
0.0 1.2 GO:0015695 organic cation transport(GO:0015695)
0.0 0.7 GO:0001542 ovulation from ovarian follicle(GO:0001542)
0.0 0.1 GO:1903347 negative regulation of bicellular tight junction assembly(GO:1903347)
0.0 1.2 GO:0001573 ganglioside metabolic process(GO:0001573)
0.0 0.3 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.0 0.3 GO:0010587 miRNA catabolic process(GO:0010587)
0.0 0.1 GO:0070105 positive regulation of interleukin-6-mediated signaling pathway(GO:0070105)
0.0 0.3 GO:0034378 chylomicron assembly(GO:0034378)
0.0 0.2 GO:0001757 somite specification(GO:0001757)
0.0 0.4 GO:0035264 multicellular organism growth(GO:0035264)
0.0 0.2 GO:0060025 primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185) regulation of synaptic activity(GO:0060025)
0.0 0.9 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 0.2 GO:0015747 urate transport(GO:0015747)
0.0 1.0 GO:0035728 response to hepatocyte growth factor(GO:0035728)
0.0 0.1 GO:0097498 endothelial tube lumen extension(GO:0097498)
0.0 0.2 GO:1902412 regulation of mitotic cytokinesis(GO:1902412)
0.0 0.2 GO:0048549 positive regulation of pinocytosis(GO:0048549)
0.0 0.5 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.0 0.6 GO:0042359 vitamin D metabolic process(GO:0042359)
0.0 0.1 GO:0034372 very-low-density lipoprotein particle remodeling(GO:0034372)
0.0 0.4 GO:0052695 cellular glucuronidation(GO:0052695)
0.0 0.1 GO:0072221 distal convoluted tubule development(GO:0072025) metanephric distal convoluted tubule development(GO:0072221)
0.0 0.1 GO:1903935 response to sodium arsenite(GO:1903935) cellular response to sodium arsenite(GO:1903936)
0.0 0.3 GO:2001224 positive regulation of neuron migration(GO:2001224)
0.0 0.3 GO:0010592 positive regulation of lamellipodium assembly(GO:0010592)
0.0 0.0 GO:0032661 regulation of interleukin-18 production(GO:0032661)
0.0 0.3 GO:0050773 regulation of dendrite development(GO:0050773)
0.0 0.2 GO:0051415 interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418)
0.0 0.3 GO:0043518 negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518)
0.0 1.3 GO:0018149 peptide cross-linking(GO:0018149)
0.0 0.4 GO:0036149 phosphatidylinositol acyl-chain remodeling(GO:0036149)
0.0 0.5 GO:0019373 epoxygenase P450 pathway(GO:0019373)
0.0 0.1 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.0 0.1 GO:1903300 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.0 0.3 GO:0038180 nerve growth factor signaling pathway(GO:0038180)
0.0 0.7 GO:0022400 regulation of rhodopsin mediated signaling pathway(GO:0022400)
0.0 0.0 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.0 0.1 GO:1904425 negative regulation of GTP binding(GO:1904425)
0.0 0.4 GO:2000001 regulation of DNA damage checkpoint(GO:2000001)
0.0 0.2 GO:0045040 protein import into mitochondrial outer membrane(GO:0045040)
0.0 0.1 GO:0043126 regulation of 1-phosphatidylinositol 4-kinase activity(GO:0043126) positive regulation of 1-phosphatidylinositol 4-kinase activity(GO:0043128)
0.0 0.9 GO:0010107 potassium ion import(GO:0010107)
0.0 0.4 GO:0050908 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.0 1.1 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 0.3 GO:0045176 apical protein localization(GO:0045176)
0.0 0.4 GO:0035855 megakaryocyte development(GO:0035855)
0.0 0.5 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.0 0.7 GO:0016577 histone demethylation(GO:0016577)
0.0 0.2 GO:0035563 positive regulation of chromatin binding(GO:0035563)
0.0 0.2 GO:0090646 mitochondrial tRNA processing(GO:0090646)
0.0 0.4 GO:0009954 proximal/distal pattern formation(GO:0009954)
0.0 0.2 GO:0009812 flavonoid metabolic process(GO:0009812)
0.0 0.5 GO:0031572 G2 DNA damage checkpoint(GO:0031572)
0.0 0.2 GO:0046951 ketone body biosynthetic process(GO:0046951)
0.0 0.7 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.0 0.3 GO:0042346 positive regulation of NF-kappaB import into nucleus(GO:0042346)
0.0 1.4 GO:0070268 cornification(GO:0070268)
0.0 0.2 GO:0034356 NAD biosynthesis via nicotinamide riboside salvage pathway(GO:0034356)
0.0 0.3 GO:0006054 N-acetylneuraminate metabolic process(GO:0006054)
0.0 0.4 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.2 GO:0034686 integrin alphav-beta8 complex(GO:0034686)
0.3 3.3 GO:0005610 laminin-5 complex(GO:0005610)
0.3 1.2 GO:0016939 kinesin II complex(GO:0016939)
0.3 2.1 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
0.2 2.5 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.2 0.8 GO:0031417 NatC complex(GO:0031417)
0.1 1.0 GO:0043541 UDP-N-acetylglucosamine transferase complex(GO:0043541)
0.1 0.9 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.1 0.3 GO:0036194 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.1 0.6 GO:1990131 Gtr1-Gtr2 GTPase complex(GO:1990131)
0.1 0.5 GO:0097513 myosin II filament(GO:0097513)
0.1 0.9 GO:0005955 calcineurin complex(GO:0005955)
0.1 0.3 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
0.1 0.4 GO:1990667 PCSK9-AnxA2 complex(GO:1990667)
0.1 0.4 GO:0071149 TEAD-2-YAP complex(GO:0071149)
0.1 0.5 GO:0072558 NLRP1 inflammasome complex(GO:0072558)
0.1 0.5 GO:0034715 pICln-Sm protein complex(GO:0034715)
0.1 7.9 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.1 2.3 GO:0005605 basal lamina(GO:0005605)
0.1 0.5 GO:0070552 BRISC complex(GO:0070552)
0.1 0.3 GO:0009328 phenylalanine-tRNA ligase complex(GO:0009328)
0.0 0.4 GO:0061617 MICOS complex(GO:0061617)
0.0 0.5 GO:0000243 commitment complex(GO:0000243)
0.0 1.7 GO:0071437 invadopodium(GO:0071437)
0.0 4.0 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 0.6 GO:0070938 contractile ring(GO:0070938)
0.0 0.8 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 0.4 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.0 0.7 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 0.3 GO:0099572 postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)
0.0 0.2 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0 0.7 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.0 0.2 GO:0008275 gamma-tubulin small complex(GO:0008275)
0.0 0.2 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.0 3.6 GO:0005901 caveola(GO:0005901)
0.0 0.1 GO:0042585 germinal vesicle(GO:0042585)
0.0 1.0 GO:0043231 intracellular membrane-bounded organelle(GO:0043231)
0.0 0.3 GO:0097470 ribbon synapse(GO:0097470)
0.0 0.2 GO:0030678 mitochondrial ribonuclease P complex(GO:0030678)
0.0 0.7 GO:0001891 phagocytic cup(GO:0001891)
0.0 1.6 GO:0001533 cornified envelope(GO:0001533)
0.0 0.6 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 0.3 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0 0.4 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 0.4 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.0 1.1 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.2 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 2.9 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 0.1 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.0 0.5 GO:0097228 sperm principal piece(GO:0097228)
0.0 0.3 GO:1990023 mitotic spindle midzone(GO:1990023)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 3.3 GO:0055100 adiponectin binding(GO:0055100)
0.6 9.6 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.4 1.2 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.3 1.7 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.3 2.2 GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.2 0.9 GO:0008281 sulfonylurea receptor activity(GO:0008281)
0.2 3.3 GO:0004022 alcohol dehydrogenase (NAD) activity(GO:0004022)
0.2 1.0 GO:0050509 N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity(GO:0050509)
0.2 2.3 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.2 0.5 GO:1902271 D3 vitamins binding(GO:1902271)
0.2 0.8 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
0.2 5.8 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.1 0.4 GO:0034041 sterol-transporting ATPase activity(GO:0034041)
0.1 2.5 GO:0000150 recombinase activity(GO:0000150)
0.1 2.0 GO:1990459 transferrin receptor binding(GO:1990459)
0.1 0.5 GO:0004082 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.1 1.2 GO:0019534 toxin transporter activity(GO:0019534)
0.1 1.3 GO:0030280 structural constituent of epidermis(GO:0030280)
0.1 0.9 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.1 4.3 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.1 1.3 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.1 1.0 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.1 0.5 GO:0004556 alpha-amylase activity(GO:0004556)
0.1 2.4 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.1 0.9 GO:0004111 creatine kinase activity(GO:0004111)
0.1 0.3 GO:0004813 alanine-tRNA ligase activity(GO:0004813)
0.1 0.3 GO:0005477 pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.1 0.5 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.1 0.6 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
0.1 0.2 GO:0047280 nicotinamide phosphoribosyltransferase activity(GO:0047280)
0.1 0.5 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
0.1 0.9 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.1 0.3 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.1 0.3 GO:0004906 interferon-gamma receptor activity(GO:0004906)
0.1 0.8 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.1 0.3 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
0.1 2.0 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.1 0.2 GO:0052590 sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity(GO:0052590) sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity(GO:0052591)
0.0 0.7 GO:0005221 intracellular cyclic nucleotide activated cation channel activity(GO:0005221) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.0 1.4 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 1.2 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 0.9 GO:0008417 fucosyltransferase activity(GO:0008417)
0.0 0.1 GO:0005499 vitamin D binding(GO:0005499)
0.0 0.3 GO:0047894 flavonol 3-sulfotransferase activity(GO:0047894) steroid sulfotransferase activity(GO:0050294)
0.0 0.1 GO:0008892 guanine deaminase activity(GO:0008892)
0.0 0.3 GO:0004797 deoxycytidine kinase activity(GO:0004137) thymidine kinase activity(GO:0004797)
0.0 0.2 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.0 0.7 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 0.6 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0 1.0 GO:0042923 neuropeptide binding(GO:0042923)
0.0 0.2 GO:0033754 indoleamine 2,3-dioxygenase activity(GO:0033754)
0.0 0.3 GO:0030267 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.0 0.3 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.0 0.2 GO:0035515 oxidative RNA demethylase activity(GO:0035515)
0.0 0.1 GO:0008384 IkappaB kinase activity(GO:0008384)
0.0 0.4 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.0 1.0 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.3 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.0 0.3 GO:0003720 telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.0 0.9 GO:0035198 miRNA binding(GO:0035198)
0.0 4.5 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 1.0 GO:0004029 aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.0 1.0 GO:0001223 transcription coactivator binding(GO:0001223)
0.0 0.4 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.0 0.5 GO:0098505 G-rich strand telomeric DNA binding(GO:0098505)
0.0 0.2 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.0 0.7 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.3 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.0 0.4 GO:0008970 phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
0.0 0.9 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 1.5 GO:0030507 spectrin binding(GO:0030507)
0.0 0.9 GO:0017166 vinculin binding(GO:0017166)
0.0 0.2 GO:1901702 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.0 0.7 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 3.4 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 1.2 GO:0046966 thyroid hormone receptor binding(GO:0046966)
0.0 0.1 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.0 1.8 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.8 GO:0001972 retinoic acid binding(GO:0001972)
0.0 0.5 GO:0031005 filamin binding(GO:0031005)
0.0 0.1 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.0 0.5 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.0 1.1 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.2 GO:0004887 thyroid hormone receptor activity(GO:0004887)
0.0 0.7 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.9 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.4 GO:0000980 RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980)
0.0 0.3 GO:0048156 tau protein binding(GO:0048156)
0.0 0.7 GO:0030371 translation repressor activity(GO:0030371)
0.0 1.0 GO:0050681 androgen receptor binding(GO:0050681)
0.0 0.1 GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)
0.0 0.5 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0 0.2 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.6 GO:0032452 histone demethylase activity(GO:0032452)
0.0 0.2 GO:0015266 protein channel activity(GO:0015266)
0.0 0.2 GO:0045504 dynein heavy chain binding(GO:0045504)
0.0 2.0 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.0 0.2 GO:0071837 HMG box domain binding(GO:0071837)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.3 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.1 8.6 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.1 4.2 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.1 5.6 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.1 2.1 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 3.4 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 0.9 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 1.3 PID S1P META PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.0 0.3 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.0 2.6 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 1.8 PID ERBB1 RECEPTOR PROXIMAL PATHWAY EGF receptor (ErbB1) signaling pathway
0.0 1.2 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions
0.0 3.3 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 8.5 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.5 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 1.2 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 0.9 PID EPHB FWD PATHWAY EPHB forward signaling
0.0 1.3 PID BMP PATHWAY BMP receptor signaling
0.0 0.7 PID RHODOPSIN PATHWAY Visual signal transduction: Rods

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.2 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.1 0.1 REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein
0.1 1.4 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.1 2.4 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1 4.7 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.1 0.5 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.1 3.9 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.0 1.0 REACTOME ACTIVATED POINT MUTANTS OF FGFR2 Genes involved in Activated point mutants of FGFR2
0.0 2.4 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.9 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 2.9 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 3.9 REACTOME CELL JUNCTION ORGANIZATION Genes involved in Cell junction organization
0.0 1.3 REACTOME INWARDLY RECTIFYING K CHANNELS Genes involved in Inwardly rectifying K+ channels
0.0 4.5 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.5 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0 1.1 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 0.4 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.0 0.9 REACTOME LIPOPROTEIN METABOLISM Genes involved in Lipoprotein metabolism
0.0 1.0 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.6 REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.0 0.8 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.0 0.5 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.3 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.7 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 0.2 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.0 0.3 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.0 0.3 REACTOME ARMS MEDIATED ACTIVATION Genes involved in ARMS-mediated activation
0.0 0.3 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 0.2 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.0 0.5 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo