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SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for HOXC10_HOXD13

Z-value: 1.89

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Transcription factors associated with HOXC10_HOXD13

Gene Symbol Gene ID Gene Info
HOXC10
ENSG00000180818.4 homeobox C10
HOXD13
ENSG00000128714.5 homeobox D13

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HOXC10hg19_v2_chr12_+_54378923_54378970-0.975.4e-13Click!
HOXD13hg19_v2_chr2_+_176957619_176957619-0.732.8e-04Click!

Activity profile of HOXC10_HOXD13 motif

Sorted Z-values of HOXC10_HOXD13 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr8_-_49834299 16.37 ENST00000396822.1
SNAI2
snail family zinc finger 2
chr1_+_153003671 12.05 ENST00000307098.4
SPRR1B
small proline-rich protein 1B
chr15_-_83952071 11.26 ENST00000569704.1
BNC1
basonuclin 1
chr1_+_209859510 8.04 ENST00000367028.2
ENST00000261465.1
HSD11B1
hydroxysteroid (11-beta) dehydrogenase 1
chr4_+_71384257 7.30 ENST00000339336.4
AMTN
amelotin
chrX_-_73072534 7.16 ENST00000429829.1
XIST
X inactive specific transcript (non-protein coding)
chr2_-_216300784 6.86 ENST00000421182.1
ENST00000432072.2
ENST00000323926.6
ENST00000336916.4
ENST00000357867.4
ENST00000359671.1
ENST00000346544.3
ENST00000345488.5
ENST00000357009.2
ENST00000446046.1
ENST00000356005.4
ENST00000443816.1
ENST00000426059.1
ENST00000354785.4
FN1
fibronectin 1
chr4_+_71384300 6.45 ENST00000504451.1
AMTN
amelotin
chr21_+_39644395 6.05 ENST00000398934.1
KCNJ15
potassium inwardly-rectifying channel, subfamily J, member 15
chr3_-_52090461 5.72 ENST00000296483.6
ENST00000495880.1
DUSP7
dual specificity phosphatase 7
chr21_+_39644305 5.65 ENST00000398930.1
KCNJ15
potassium inwardly-rectifying channel, subfamily J, member 15
chr21_+_39644172 5.56 ENST00000398932.1
KCNJ15
potassium inwardly-rectifying channel, subfamily J, member 15
chr11_+_93754513 5.55 ENST00000315765.9
HEPHL1
hephaestin-like 1
chr3_-_151034734 5.52 ENST00000260843.4
GPR87
G protein-coupled receptor 87
chr8_-_124553437 5.41 ENST00000517956.1
ENST00000443022.2
FBXO32
F-box protein 32
chr2_+_158114051 5.36 ENST00000259056.4
GALNT5
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 5 (GalNAc-T5)
chr11_+_118401706 5.34 ENST00000411589.2
ENST00000442938.2
ENST00000359862.4
TMEM25
transmembrane protein 25
chr4_+_169013666 5.11 ENST00000359299.3
ANXA10
annexin A10
chr7_-_41742697 5.04 ENST00000242208.4
INHBA
inhibin, beta A
chrM_+_4431 4.99 ENST00000361453.3
MT-ND2
mitochondrially encoded NADH dehydrogenase 2
chr13_-_46626847 4.86 ENST00000242848.4
ENST00000282007.3
ZC3H13
zinc finger CCCH-type containing 13
chr19_-_54676846 4.81 ENST00000301187.4
TMC4
transmembrane channel-like 4
chr21_+_39644214 4.81 ENST00000438657.1
KCNJ15
potassium inwardly-rectifying channel, subfamily J, member 15
chr15_-_75017711 4.76 ENST00000567032.1
ENST00000564596.1
ENST00000566503.1
ENST00000395049.4
ENST00000395048.2
ENST00000379727.3
CYP1A1
cytochrome P450, family 1, subfamily A, polypeptide 1
chr19_-_54676884 4.70 ENST00000376591.4
TMC4
transmembrane channel-like 4
chr1_+_32042131 4.61 ENST00000271064.7
ENST00000537531.1
TINAGL1
tubulointerstitial nephritis antigen-like 1
chrX_+_105936982 4.59 ENST00000418562.1
RNF128
ring finger protein 128, E3 ubiquitin protein ligase
chr1_+_32042105 4.55 ENST00000457433.2
ENST00000441210.2
TINAGL1
tubulointerstitial nephritis antigen-like 1
chr18_+_61554932 4.29 ENST00000299502.4
ENST00000457692.1
ENST00000413956.1
SERPINB2
serpin peptidase inhibitor, clade B (ovalbumin), member 2
chr21_-_28217721 4.19 ENST00000284984.3
ADAMTS1
ADAM metallopeptidase with thrombospondin type 1 motif, 1
chrM_+_12331 4.00 ENST00000361567.2
MT-ND5
mitochondrially encoded NADH dehydrogenase 5
chr4_-_68749699 3.99 ENST00000545541.1
TMPRSS11D
transmembrane protease, serine 11D
chrX_+_105937068 3.97 ENST00000324342.3
RNF128
ring finger protein 128, E3 ubiquitin protein ligase
chr3_+_189507460 3.81 ENST00000434928.1
TP63
tumor protein p63
chr12_-_52828147 3.68 ENST00000252245.5
KRT75
keratin 75
chr11_-_119999539 3.62 ENST00000541857.1
TRIM29
tripartite motif containing 29
chrM_-_14670 3.55 ENST00000361681.2
MT-ND6
mitochondrially encoded NADH dehydrogenase 6
chr11_+_118401899 3.55 ENST00000528373.1
ENST00000544878.1
ENST00000354284.4
ENST00000533137.1
ENST00000532762.1
ENST00000526973.1
ENST00000354064.7
ENST00000533102.1
ENST00000313236.5
ENST00000527267.1
ENST00000524725.1
ENST00000533689.1
TMEM25
transmembrane protein 25
chr16_+_55600580 3.53 ENST00000457326.2
CAPNS2
calpain, small subunit 2
chr11_-_119999611 3.52 ENST00000529044.1
TRIM29
tripartite motif containing 29
chr3_+_160394940 3.48 ENST00000320767.2
ARL14
ADP-ribosylation factor-like 14
chr1_-_43919346 3.32 ENST00000372430.3
ENST00000372433.1
ENST00000372434.1
ENST00000486909.1
HYI
hydroxypyruvate isomerase (putative)
chr17_-_39684550 3.30 ENST00000455635.1
ENST00000361566.3
KRT19
keratin 19
chr14_-_21493123 3.15 ENST00000556147.1
ENST00000554489.1
ENST00000555657.1
ENST00000557274.1
ENST00000555158.1
ENST00000554833.1
ENST00000555384.1
ENST00000556420.1
ENST00000554893.1
ENST00000553503.1
ENST00000555733.1
ENST00000553867.1
ENST00000397856.3
ENST00000397855.3
ENST00000556008.1
ENST00000557182.1
ENST00000554483.1
ENST00000556688.1
ENST00000397853.3
ENST00000556329.2
ENST00000554143.1
ENST00000397851.2
ENST00000555142.1
ENST00000557676.1
ENST00000556924.1
NDRG2
NDRG family member 2
chr4_+_69313145 3.09 ENST00000305363.4
TMPRSS11E
transmembrane protease, serine 11E
chr13_-_46626820 3.00 ENST00000428921.1
ZC3H13
zinc finger CCCH-type containing 13
chr1_+_160370344 2.95 ENST00000368061.2
VANGL2
VANGL planar cell polarity protein 2
chr10_-_4720333 2.90 ENST00000430998.2
LINC00704
long intergenic non-protein coding RNA 704
chr8_+_38831683 2.88 ENST00000302495.4
HTRA4
HtrA serine peptidase 4
chr1_-_43919573 2.86 ENST00000372432.1
ENST00000372425.4
ENST00000583037.1
HYI
hydroxypyruvate isomerase (putative)
chr5_-_42825983 2.85 ENST00000506577.1
SEPP1
selenoprotein P, plasma, 1
chr3_+_189507432 2.85 ENST00000354600.5
TP63
tumor protein p63
chr7_+_134551583 2.83 ENST00000435928.1
CALD1
caldesmon 1
chr7_+_134464376 2.83 ENST00000454108.1
ENST00000361675.2
CALD1
caldesmon 1
chr4_+_48018781 2.80 ENST00000295461.5
NIPAL1
NIPA-like domain containing 1
chr7_+_40174565 2.79 ENST00000309930.5
ENST00000401647.2
ENST00000335693.4
ENST00000413931.1
ENST00000416370.1
ENST00000540834.1
C7orf10
succinylCoA:glutarate-CoA transferase
chr9_+_130911770 2.77 ENST00000372998.1
LCN2
lipocalin 2
chr12_-_8814669 2.75 ENST00000535411.1
ENST00000540087.1
MFAP5
microfibrillar associated protein 5
chr21_-_28215332 2.72 ENST00000517777.1
ADAMTS1
ADAM metallopeptidase with thrombospondin type 1 motif, 1
chr1_+_52682052 2.70 ENST00000371591.1
ZFYVE9
zinc finger, FYVE domain containing 9
chr3_+_190105909 2.68 ENST00000456423.1
CLDN16
claudin 16
chr6_-_75828774 2.64 ENST00000493109.2
COL12A1
collagen, type XII, alpha 1
chr2_+_210444142 2.63 ENST00000360351.4
ENST00000361559.4
MAP2
microtubule-associated protein 2
chr9_+_130911723 2.63 ENST00000277480.2
ENST00000373013.2
ENST00000540948.1
LCN2
lipocalin 2
chr18_-_68004529 2.61 ENST00000578633.1
RP11-484N16.1
RP11-484N16.1
chr10_-_4720301 2.60 ENST00000449712.1
LINC00704
long intergenic non-protein coding RNA 704
chr4_-_68749745 2.56 ENST00000283916.6
TMPRSS11D
transmembrane protease, serine 11D
chr1_-_152386732 2.54 ENST00000271835.3
CRNN
cornulin
chr14_-_61748550 2.50 ENST00000555868.1
TMEM30B
transmembrane protein 30B
chr4_-_87028478 2.47 ENST00000515400.1
ENST00000395157.3
MAPK10
mitogen-activated protein kinase 10
chr18_+_21032781 2.47 ENST00000339486.3
RIOK3
RIO kinase 3
chr18_-_12656715 2.44 ENST00000462226.1
ENST00000497844.2
ENST00000309836.5
ENST00000453447.2
SPIRE1
spire-type actin nucleation factor 1
chr16_+_57653625 2.43 ENST00000567553.1
ENST00000565314.1
GPR56
G protein-coupled receptor 56
chr16_+_57653596 2.42 ENST00000568791.1
ENST00000570044.1
GPR56
G protein-coupled receptor 56
chr9_+_22646189 2.42 ENST00000436786.1
RP11-399D6.2
RP11-399D6.2
chr4_-_153601136 2.38 ENST00000504064.1
ENST00000304385.3
TMEM154
transmembrane protein 154
chr22_-_30814469 2.37 ENST00000598426.1
KIAA1658
KIAA1658
chr13_-_38172863 2.32 ENST00000541481.1
ENST00000379743.4
ENST00000379742.4
ENST00000379749.4
ENST00000541179.1
ENST00000379747.4
POSTN
periostin, osteoblast specific factor
chr18_+_61445205 2.32 ENST00000431370.1
SERPINB7
serpin peptidase inhibitor, clade B (ovalbumin), member 7
chr2_+_210443993 2.29 ENST00000392193.1
MAP2
microtubule-associated protein 2
chrX_+_99899180 2.29 ENST00000373004.3
SRPX2
sushi-repeat containing protein, X-linked 2
chr7_+_90338712 2.27 ENST00000265741.3
ENST00000406263.1
CDK14
cyclin-dependent kinase 14
chr5_+_167182003 2.26 ENST00000520394.1
TENM2
teneurin transmembrane protein 2
chr20_-_50722183 2.25 ENST00000371523.4
ZFP64
ZFP64 zinc finger protein
chr20_+_58179582 2.21 ENST00000371015.1
ENST00000395639.4
PHACTR3
phosphatase and actin regulator 3
chr12_-_49418407 2.19 ENST00000526209.1
KMT2D
lysine (K)-specific methyltransferase 2D
chr18_+_61445007 2.19 ENST00000447428.1
ENST00000546027.1
SERPINB7
serpin peptidase inhibitor, clade B (ovalbumin), member 7
chr12_-_95044309 2.18 ENST00000261226.4
TMCC3
transmembrane and coiled-coil domain family 3
chrX_-_15619076 2.14 ENST00000252519.3
ACE2
angiotensin I converting enzyme 2
chr17_-_39553844 2.14 ENST00000251645.2
KRT31
keratin 31
chr1_+_174844645 2.14 ENST00000486220.1
RABGAP1L
RAB GTPase activating protein 1-like
chr18_-_53253323 2.12 ENST00000540999.1
ENST00000563888.2
TCF4
transcription factor 4
chr3_-_121379739 2.10 ENST00000428394.2
ENST00000314583.3
HCLS1
hematopoietic cell-specific Lyn substrate 1
chr3_-_138048682 2.07 ENST00000383180.2
NME9
NME/NM23 family member 9
chrX_+_102840408 2.07 ENST00000468024.1
ENST00000472484.1
ENST00000415568.2
ENST00000490644.1
ENST00000459722.1
ENST00000472745.1
ENST00000494801.1
ENST00000434216.2
ENST00000425011.1
TCEAL4
transcription elongation factor A (SII)-like 4
chr1_+_116654376 2.06 ENST00000369500.3
MAB21L3
mab-21-like 3 (C. elegans)
chr3_+_57875738 2.04 ENST00000417128.1
ENST00000438794.1
SLMAP
sarcolemma associated protein
chr16_-_4852915 2.04 ENST00000322048.7
ROGDI
rogdi homolog (Drosophila)
chr12_-_26278030 2.01 ENST00000242728.4
BHLHE41
basic helix-loop-helix family, member e41
chr7_-_92747269 2.01 ENST00000446617.1
ENST00000379958.2
SAMD9
sterile alpha motif domain containing 9
chrX_-_30993201 2.00 ENST00000288422.2
ENST00000378932.2
TAB3
TGF-beta activated kinase 1/MAP3K7 binding protein 3
chr1_+_12524965 1.99 ENST00000471923.1
VPS13D
vacuolar protein sorting 13 homolog D (S. cerevisiae)
chrX_-_3264682 1.97 ENST00000217939.6
MXRA5
matrix-remodelling associated 5
chr18_-_53253112 1.96 ENST00000568673.1
ENST00000562847.1
ENST00000568147.1
TCF4
transcription factor 4
chr12_+_8995832 1.95 ENST00000541459.1
A2ML1
alpha-2-macroglobulin-like 1
chr1_+_152957707 1.94 ENST00000368762.1
SPRR1A
small proline-rich protein 1A
chrY_+_15418467 1.90 ENST00000595988.1
AC010877.1
Uncharacterized protein
chr6_-_10415470 1.87 ENST00000379604.2
ENST00000379613.3
TFAP2A
transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
chr3_+_177159695 1.86 ENST00000442937.1
LINC00578
long intergenic non-protein coding RNA 578
chr3_-_185538849 1.83 ENST00000421047.2
IGF2BP2
insulin-like growth factor 2 mRNA binding protein 2
chr5_+_36608280 1.82 ENST00000513646.1
SLC1A3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr1_-_209957882 1.80 ENST00000294811.1
C1orf74
chromosome 1 open reading frame 74
chrM_+_14741 1.80 ENST00000361789.2
MT-CYB
mitochondrially encoded cytochrome b
chr17_-_62340581 1.77 ENST00000258991.3
ENST00000583738.1
ENST00000584379.1
TEX2
testis expressed 2
chr8_-_73793975 1.75 ENST00000523881.1
RP11-1145L24.1
RP11-1145L24.1
chr5_-_137475071 1.72 ENST00000265191.2
NME5
NME/NM23 family member 5
chr7_+_22766766 1.71 ENST00000426291.1
ENST00000401651.1
ENST00000258743.5
ENST00000420258.2
ENST00000407492.1
ENST00000401630.3
ENST00000406575.1
IL6
interleukin 6 (interferon, beta 2)
chr1_-_55341551 1.68 ENST00000537443.1
DHCR24
24-dehydrocholesterol reductase
chr3_-_195310802 1.68 ENST00000421243.1
ENST00000453131.1
APOD
apolipoprotein D
chr9_+_70856397 1.67 ENST00000360171.6
CBWD3
COBW domain containing 3
chr10_-_62332357 1.65 ENST00000503366.1
ANK3
ankyrin 3, node of Ranvier (ankyrin G)
chr2_+_210444748 1.64 ENST00000392194.1
MAP2
microtubule-associated protein 2
chr11_-_128392085 1.63 ENST00000526145.2
ENST00000531611.1
ENST00000319397.6
ENST00000345075.4
ENST00000535549.1
ETS1
v-ets avian erythroblastosis virus E26 oncogene homolog 1
chr12_+_130646999 1.63 ENST00000539839.1
ENST00000229030.4
FZD10
frizzled family receptor 10
chr7_-_75401513 1.62 ENST00000005180.4
CCL26
chemokine (C-C motif) ligand 26
chr6_+_35310391 1.62 ENST00000337400.2
ENST00000311565.4
ENST00000540939.1
PPARD
peroxisome proliferator-activated receptor delta
chr12_+_1738363 1.61 ENST00000397196.2
WNT5B
wingless-type MMTV integration site family, member 5B
chr6_-_56716686 1.61 ENST00000520645.1
DST
dystonin
chr10_-_98031265 1.61 ENST00000224337.5
ENST00000371176.2
BLNK
B-cell linker
chr2_-_151344172 1.61 ENST00000375734.2
ENST00000263895.4
ENST00000454202.1
RND3
Rho family GTPase 3
chr20_+_19870167 1.60 ENST00000440354.2
RIN2
Ras and Rab interactor 2
chr11_-_102826434 1.60 ENST00000340273.4
ENST00000260302.3
MMP13
matrix metallopeptidase 13 (collagenase 3)
chr11_-_7961141 1.59 ENST00000360759.3
OR10A3
olfactory receptor, family 10, subfamily A, member 3
chr3_-_69249863 1.54 ENST00000478263.1
ENST00000462512.1
FRMD4B
FERM domain containing 4B
chr3_-_18480260 1.54 ENST00000454909.2
SATB1
SATB homeobox 1
chr18_+_20494078 1.53 ENST00000579124.1
ENST00000577588.1
ENST00000582354.1
ENST00000581819.1
RBBP8
retinoblastoma binding protein 8
chr2_+_131769256 1.52 ENST00000355771.3
ARHGEF4
Rho guanine nucleotide exchange factor (GEF) 4
chr4_+_39046615 1.51 ENST00000261425.3
ENST00000508137.2
KLHL5
kelch-like family member 5
chr12_+_14561422 1.51 ENST00000541056.1
ATF7IP
activating transcription factor 7 interacting protein
chr12_+_25205568 1.50 ENST00000548766.1
ENST00000556887.1
LRMP
lymphoid-restricted membrane protein
chr11_+_113185778 1.50 ENST00000524580.2
TTC12
tetratricopeptide repeat domain 12
chr6_-_111888474 1.49 ENST00000368735.1
TRAF3IP2
TRAF3 interacting protein 2
chr2_+_169923577 1.49 ENST00000432060.2
DHRS9
dehydrogenase/reductase (SDR family) member 9
chr6_+_130339710 1.48 ENST00000526087.1
ENST00000533560.1
ENST00000361794.2
L3MBTL3
l(3)mbt-like 3 (Drosophila)
chr12_+_70219052 1.45 ENST00000552032.2
ENST00000547771.2
MYRFL
myelin regulatory factor-like
chr9_-_14180778 1.44 ENST00000380924.1
ENST00000543693.1
NFIB
nuclear factor I/B
chr18_+_32173276 1.43 ENST00000591816.1
ENST00000588125.1
ENST00000598334.1
ENST00000588684.1
ENST00000554864.3
ENST00000399121.5
ENST00000595022.1
ENST00000269190.7
ENST00000399097.3
DTNA
dystrobrevin, alpha
chr2_+_138721850 1.42 ENST00000329366.4
ENST00000280097.3
HNMT
histamine N-methyltransferase
chr6_+_42847348 1.41 ENST00000493763.1
ENST00000304734.5
RPL7L1
ribosomal protein L7-like 1
chr11_+_63606373 1.40 ENST00000402010.2
ENST00000315032.8
ENST00000377809.4
ENST00000413835.2
ENST00000377810.3
MARK2
MAP/microtubule affinity-regulating kinase 2
chr18_+_34124507 1.40 ENST00000591635.1
FHOD3
formin homology 2 domain containing 3
chr12_-_117799446 1.40 ENST00000317775.6
ENST00000344089.3
NOS1
nitric oxide synthase 1 (neuronal)
chr20_+_62327996 1.39 ENST00000369996.1
TNFRSF6B
tumor necrosis factor receptor superfamily, member 6b, decoy
chr5_-_43412418 1.39 ENST00000537013.1
ENST00000361115.4
CCL28
chemokine (C-C motif) ligand 28
chr17_-_48943706 1.38 ENST00000499247.2
TOB1
transducer of ERBB2, 1
chr16_-_21431078 1.38 ENST00000458643.2
NPIPB3
nuclear pore complex interacting protein family, member B3
chr1_+_90460661 1.38 ENST00000340281.4
ENST00000361911.5
ENST00000370447.3
ENST00000455342.2
ZNF326
zinc finger protein 326
chr8_-_114449112 1.37 ENST00000455883.2
ENST00000352409.3
ENST00000297405.5
CSMD3
CUB and Sushi multiple domains 3
chr2_+_66662510 1.37 ENST00000272369.9
ENST00000407092.2
MEIS1
Meis homeobox 1
chr11_+_129939779 1.35 ENST00000533195.1
ENST00000533713.1
ENST00000528499.1
ENST00000539648.1
ENST00000263574.5
APLP2
amyloid beta (A4) precursor-like protein 2
chr22_+_50981079 1.35 ENST00000609268.1
CTA-384D8.34
CTA-384D8.34
chr4_-_48018680 1.34 ENST00000513178.1
CNGA1
cyclic nucleotide gated channel alpha 1
chr1_+_17559776 1.31 ENST00000537499.1
ENST00000413717.2
ENST00000536552.1
PADI1
peptidyl arginine deiminase, type I
chr9_+_115913222 1.30 ENST00000259392.3
SLC31A2
solute carrier family 31 (copper transporter), member 2
chr18_-_33709268 1.30 ENST00000269187.5
ENST00000590986.1
ENST00000440549.2
SLC39A6
solute carrier family 39 (zinc transporter), member 6
chr4_+_75174180 1.30 ENST00000413830.1
EPGN
epithelial mitogen
chr13_-_33112823 1.29 ENST00000504114.1
N4BP2L2
NEDD4 binding protein 2-like 2
chr3_-_183145873 1.28 ENST00000447025.2
ENST00000414362.2
ENST00000328913.3
MCF2L2
MCF.2 cell line derived transforming sequence-like 2
chr17_+_35851570 1.27 ENST00000394386.1
DUSP14
dual specificity phosphatase 14
chr7_+_134576317 1.26 ENST00000424922.1
ENST00000495522.1
CALD1
caldesmon 1
chr2_-_207023918 1.25 ENST00000455934.2
ENST00000449699.1
ENST00000454195.1
NDUFS1
NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)
chr20_+_52105495 1.25 ENST00000439873.2
AL354993.1
Cell growth-inhibiting protein 7; HCG1784586; Uncharacterized protein
chr7_+_138915102 1.25 ENST00000486663.1
UBN2
ubinuclein 2
chrX_+_107683096 1.24 ENST00000328300.6
ENST00000361603.2
COL4A5
collagen, type IV, alpha 5
chr12_+_80838126 1.24 ENST00000266688.5
PTPRQ
protein tyrosine phosphatase, receptor type, Q
chr8_+_26150628 1.24 ENST00000523925.1
ENST00000315985.7
PPP2R2A
protein phosphatase 2, regulatory subunit B, alpha
chr3_+_41241596 1.23 ENST00000450969.1
CTNNB1
catenin (cadherin-associated protein), beta 1, 88kDa
chr7_+_134464414 1.23 ENST00000361901.2
CALD1
caldesmon 1
chr6_+_151042224 1.22 ENST00000358517.2
PLEKHG1
pleckstrin homology domain containing, family G (with RhoGef domain) member 1
chr2_-_197675000 1.21 ENST00000342506.2
C2orf66
chromosome 2 open reading frame 66
chr12_-_118628350 1.20 ENST00000537952.1
ENST00000537822.1
TAOK3
TAO kinase 3
chr18_-_47018897 1.20 ENST00000418495.1
RPL17
ribosomal protein L17
chr4_-_48018580 1.20 ENST00000514170.1
CNGA1
cyclic nucleotide gated channel alpha 1
chr12_+_93096759 1.19 ENST00000544406.2
C12orf74
chromosome 12 open reading frame 74
chr3_-_71353892 1.19 ENST00000484350.1
FOXP1
forkhead box P1
chr10_+_85933494 1.17 ENST00000372126.3
C10orf99
chromosome 10 open reading frame 99
chr8_-_103424986 1.17 ENST00000521922.1
UBR5
ubiquitin protein ligase E3 component n-recognin 5
chr14_-_35344093 1.17 ENST00000382422.2
BAZ1A
bromodomain adjacent to zinc finger domain, 1A
chr11_-_13461790 1.16 ENST00000530907.1
BTBD10
BTB (POZ) domain containing 10
chr5_+_36608422 1.16 ENST00000381918.3
SLC1A3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr11_-_26588634 1.15 ENST00000436318.2
ENST00000281268.8
MUC15
mucin 15, cell surface associated
chr8_-_103424916 1.15 ENST00000220959.4
UBR5
ubiquitin protein ligase E3 component n-recognin 5
chr1_-_9129631 1.15 ENST00000377414.3
SLC2A5
solute carrier family 2 (facilitated glucose/fructose transporter), member 5
chr6_-_33548006 1.15 ENST00000374467.3
BAK1
BCL2-antagonist/killer 1
chr17_-_38859996 1.15 ENST00000264651.2
KRT24
keratin 24
chr1_-_86848760 1.14 ENST00000460698.2
ODF2L
outer dense fiber of sperm tails 2-like
chr1_+_211432775 1.13 ENST00000419091.2
RCOR3
REST corepressor 3
chr18_-_47018769 1.13 ENST00000583637.1
ENST00000578528.1
ENST00000578532.1
ENST00000580387.1
ENST00000579248.1
ENST00000581373.1
RPL17
ribosomal protein L17
chr18_-_5396271 1.13 ENST00000579951.1
EPB41L3
erythrocyte membrane protein band 4.1-like 3
chr14_+_52164820 1.13 ENST00000554167.1
FRMD6
FERM domain containing 6

Network of associatons between targets according to the STRING database.

First level regulatory network of HOXC10_HOXD13

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
5.5 16.4 GO:0070563 negative regulation of vitamin D receptor signaling pathway(GO:0070563)
4.6 13.8 GO:0070175 positive regulation of enamel mineralization(GO:0070175)
2.3 6.9 GO:1904237 regulation of substrate-dependent cell migration, cell attachment to substrate(GO:1904235) positive regulation of substrate-dependent cell migration, cell attachment to substrate(GO:1904237)
1.7 5.0 GO:0060278 regulation of ovulation(GO:0060278) positive regulation of ovulation(GO:0060279)
1.7 6.7 GO:0007499 ectoderm and mesoderm interaction(GO:0007499)
1.6 4.8 GO:0043449 cellular alkene metabolic process(GO:0043449)
1.1 7.6 GO:0010046 response to mycotoxin(GO:0010046)
1.0 2.9 GO:0060490 orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490)
0.9 4.5 GO:0090362 positive regulation of platelet-derived growth factor production(GO:0090362)
0.7 5.4 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.6 8.6 GO:1904352 positive regulation of protein catabolic process in the vacuole(GO:1904352)
0.5 3.5 GO:0032445 fructose import(GO:0032445) carbohydrate import into cell(GO:0097319) carbohydrate import across plasma membrane(GO:0098704) fructose import across plasma membrane(GO:1990539)
0.5 2.5 GO:0039534 negative regulation of MDA-5 signaling pathway(GO:0039534)
0.5 1.4 GO:0002514 B cell tolerance induction(GO:0002514) regulation of B cell tolerance induction(GO:0002661) positive regulation of B cell tolerance induction(GO:0002663)
0.5 1.4 GO:0071879 positive regulation of adrenergic receptor signaling pathway(GO:0071879)
0.5 2.3 GO:0032571 response to vitamin K(GO:0032571)
0.4 2.7 GO:0072658 maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.4 1.7 GO:0002384 hepatic immune response(GO:0002384)
0.4 2.1 GO:0003051 angiotensin-mediated drinking behavior(GO:0003051) receptor-mediated virion attachment to host cell(GO:0046813)
0.4 1.7 GO:2000097 regulation of smooth muscle cell-matrix adhesion(GO:2000097)
0.4 1.5 GO:0001835 blastocyst hatching(GO:0001835) hatching(GO:0035188) organism emergence from protective structure(GO:0071684)
0.4 1.1 GO:1904017 cellular response to Thyroglobulin triiodothyronine(GO:1904017)
0.4 1.9 GO:0021622 optic cup structural organization(GO:0003409) oculomotor nerve morphogenesis(GO:0021622) oculomotor nerve formation(GO:0021623)
0.4 2.2 GO:0032625 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.4 2.2 GO:0001555 oocyte growth(GO:0001555)
0.4 7.1 GO:0001542 ovulation from ovarian follicle(GO:0001542)
0.3 4.5 GO:0090360 platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
0.3 3.1 GO:1902035 positive regulation of hematopoietic stem cell proliferation(GO:1902035)
0.3 21.4 GO:0010107 potassium ion import(GO:0010107)
0.3 7.8 GO:0006704 glucocorticoid biosynthetic process(GO:0006704)
0.3 3.3 GO:1901315 negative regulation of histone ubiquitination(GO:0033183) progesterone receptor signaling pathway(GO:0050847) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315)
0.3 1.9 GO:0001692 histamine metabolic process(GO:0001692)
0.3 0.3 GO:0033227 dsRNA transport(GO:0033227)
0.3 1.2 GO:0007403 glial cell fate determination(GO:0007403) canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation(GO:0061324) regulation of chromatin-mediated maintenance of transcription(GO:1904499) positive regulation of chromatin-mediated maintenance of transcription(GO:1904501) regulation of euchromatin binding(GO:1904793)
0.3 2.4 GO:0070649 polar body extrusion after meiotic divisions(GO:0040038) formin-nucleated actin cable assembly(GO:0070649)
0.3 5.4 GO:0014877 response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.3 0.8 GO:0061394 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394)
0.3 1.7 GO:0033489 cholesterol biosynthetic process via desmosterol(GO:0033489) cholesterol biosynthetic process via lathosterol(GO:0033490)
0.3 1.4 GO:1903237 negative regulation of leukocyte tethering or rolling(GO:1903237)
0.3 0.8 GO:1903515 calcium ion transport from cytosol to endoplasmic reticulum(GO:1903515)
0.3 1.1 GO:0035905 N-terminal peptidyl-lysine acetylation(GO:0018076) ascending aorta development(GO:0035905) ascending aorta morphogenesis(GO:0035910)
0.3 3.0 GO:0070779 gamma-aminobutyric acid biosynthetic process(GO:0009449) D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.3 1.3 GO:0036414 protein citrullination(GO:0018101) histone citrullination(GO:0036414)
0.2 1.6 GO:1904996 positive regulation of leukocyte adhesion to vascular endothelial cell(GO:1904996)
0.2 5.5 GO:1903830 magnesium ion transmembrane transport(GO:1903830)
0.2 1.0 GO:2000639 regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
0.2 5.1 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.2 1.0 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.2 3.8 GO:0006183 GTP biosynthetic process(GO:0006183)
0.2 0.8 GO:0010430 fatty acid omega-oxidation(GO:0010430)
0.2 2.8 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.2 1.6 GO:0043415 positive regulation of skeletal muscle tissue regeneration(GO:0043415)
0.2 1.4 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.2 2.5 GO:0007258 JUN phosphorylation(GO:0007258)
0.2 1.0 GO:2001106 regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.2 13.5 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.2 1.0 GO:0001781 neutrophil apoptotic process(GO:0001781)
0.2 0.7 GO:0021502 neural fold elevation formation(GO:0021502)
0.2 12.8 GO:0018149 peptide cross-linking(GO:0018149)
0.2 1.6 GO:0038030 non-canonical Wnt signaling pathway via MAPK cascade(GO:0038030) non-canonical Wnt signaling pathway via JNK cascade(GO:0038031)
0.2 1.0 GO:0060437 lung growth(GO:0060437)
0.2 2.3 GO:0045741 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741)
0.2 1.1 GO:0051012 microtubule sliding(GO:0051012)
0.2 0.5 GO:0035038 female pronucleus assembly(GO:0035038)
0.1 0.9 GO:0002933 lipid hydroxylation(GO:0002933)
0.1 2.9 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.1 2.3 GO:0097264 self proteolysis(GO:0097264)
0.1 2.3 GO:0010944 negative regulation of transcription by competitive promoter binding(GO:0010944)
0.1 0.8 GO:0061668 mitochondrial ribosome assembly(GO:0061668)
0.1 2.9 GO:0060044 negative regulation of cardiac muscle cell proliferation(GO:0060044)
0.1 1.1 GO:0002175 protein localization to paranode region of axon(GO:0002175)
0.1 1.1 GO:0003383 apical constriction(GO:0003383)
0.1 6.4 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.1 0.5 GO:0009236 cobalamin biosynthetic process(GO:0009236)
0.1 2.5 GO:0070863 positive regulation of protein exit from endoplasmic reticulum(GO:0070863)
0.1 1.0 GO:0072092 ureteric bud invasion(GO:0072092)
0.1 2.1 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.1 0.9 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.1 0.9 GO:0003185 primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
0.1 0.9 GO:0046098 guanine metabolic process(GO:0046098)
0.1 0.6 GO:0070980 biphenyl catabolic process(GO:0070980)
0.1 1.2 GO:0042904 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.1 1.8 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.1 1.3 GO:0035434 copper ion transmembrane transport(GO:0035434)
0.1 0.8 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.1 0.6 GO:1901727 positive regulation of histone deacetylase activity(GO:1901727)
0.1 0.3 GO:0006429 leucyl-tRNA aminoacylation(GO:0006429)
0.1 1.6 GO:0015705 iodide transport(GO:0015705)
0.1 1.2 GO:0006777 Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720) molybdopterin cofactor biosynthetic process(GO:0032324) molybdopterin cofactor metabolic process(GO:0043545) prosthetic group metabolic process(GO:0051189)
0.1 0.9 GO:1901297 positive regulation of ephrin receptor signaling pathway(GO:1901189) positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068)
0.1 0.8 GO:2000111 positive regulation of macrophage apoptotic process(GO:2000111)
0.1 2.3 GO:1902373 negative regulation of mRNA catabolic process(GO:1902373)
0.1 0.3 GO:0072356 chromosome passenger complex localization to kinetochore(GO:0072356)
0.1 12.5 GO:0016266 O-glycan processing(GO:0016266)
0.1 2.4 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.1 0.3 GO:0006540 glutamate decarboxylation to succinate(GO:0006540)
0.1 1.1 GO:2000467 positive regulation of glycogen (starch) synthase activity(GO:2000467)
0.1 0.4 GO:0006408 snRNA export from nucleus(GO:0006408)
0.1 1.6 GO:0008090 retrograde axonal transport(GO:0008090)
0.1 1.4 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.1 0.4 GO:0019482 beta-alanine metabolic process(GO:0019482)
0.1 1.5 GO:0043249 erythrocyte maturation(GO:0043249)
0.1 0.7 GO:0021943 regulation of collagen catabolic process(GO:0010710) formation of radial glial scaffolds(GO:0021943)
0.1 0.9 GO:0019255 glucose 1-phosphate metabolic process(GO:0019255)
0.1 1.7 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
0.1 0.6 GO:0036493 positive regulation of translation in response to endoplasmic reticulum stress(GO:0036493)
0.1 0.4 GO:0097045 phosphatidylserine exposure on blood platelet(GO:0097045)
0.1 1.7 GO:2000675 negative regulation of type B pancreatic cell apoptotic process(GO:2000675)
0.1 0.2 GO:0098712 L-glutamate import across plasma membrane(GO:0098712)
0.1 1.4 GO:0070307 lens fiber cell development(GO:0070307)
0.1 1.1 GO:0035973 aggrephagy(GO:0035973)
0.1 0.4 GO:0048341 paraxial mesoderm formation(GO:0048341)
0.1 0.6 GO:1902498 regulation of protein autoubiquitination(GO:1902498)
0.1 1.4 GO:0010818 T cell chemotaxis(GO:0010818)
0.1 3.0 GO:0060828 regulation of canonical Wnt signaling pathway(GO:0060828)
0.1 1.2 GO:0034197 acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197)
0.1 0.7 GO:0030913 paranodal junction assembly(GO:0030913)
0.1 0.4 GO:0035553 oxidative RNA demethylation(GO:0035513) oxidative single-stranded RNA demethylation(GO:0035553)
0.1 0.8 GO:0008286 insulin receptor signaling pathway(GO:0008286)
0.1 0.4 GO:0071460 cellular response to cell-matrix adhesion(GO:0071460)
0.1 0.1 GO:0060300 regulation of cytokine activity(GO:0060300)
0.1 0.6 GO:0048194 Golgi vesicle budding(GO:0048194)
0.1 1.6 GO:0003417 growth plate cartilage development(GO:0003417)
0.1 0.2 GO:0030505 inorganic diphosphate transport(GO:0030505)
0.1 0.7 GO:0035583 sequestering of TGFbeta in extracellular matrix(GO:0035583)
0.1 0.3 GO:0042357 thiamine diphosphate metabolic process(GO:0042357)
0.1 0.3 GO:0016098 monoterpenoid metabolic process(GO:0016098)
0.1 0.4 GO:1904796 regulation of core promoter binding(GO:1904796)
0.1 1.3 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.1 1.1 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.1 3.5 GO:0002244 hematopoietic progenitor cell differentiation(GO:0002244)
0.1 0.9 GO:0015727 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873)
0.1 2.7 GO:0007184 SMAD protein import into nucleus(GO:0007184)
0.1 0.5 GO:0046952 ketone body catabolic process(GO:0046952)
0.1 2.8 GO:0097435 fibril organization(GO:0097435)
0.1 0.4 GO:2001013 epithelial cell proliferation involved in renal tubule morphogenesis(GO:2001013)
0.1 2.8 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.1 0.7 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
0.1 0.3 GO:0009441 glycolate metabolic process(GO:0009441)
0.1 0.9 GO:0016081 synaptic vesicle docking(GO:0016081)
0.1 0.7 GO:0098814 spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.1 0.5 GO:0055118 negative regulation of striated muscle contraction(GO:0045988) negative regulation of cardiac muscle contraction(GO:0055118)
0.1 0.4 GO:0071492 cellular response to UV-A(GO:0071492)
0.1 0.2 GO:0006579 amino-acid betaine catabolic process(GO:0006579)
0.1 1.5 GO:0001783 B cell apoptotic process(GO:0001783)
0.1 6.9 GO:0001578 microtubule bundle formation(GO:0001578)
0.1 0.3 GO:0015722 canalicular bile acid transport(GO:0015722)
0.1 0.5 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.1 0.6 GO:0000447 endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000447)
0.1 1.5 GO:0055003 cardiac myofibril assembly(GO:0055003)
0.1 2.1 GO:0022400 regulation of rhodopsin mediated signaling pathway(GO:0022400)
0.1 0.5 GO:0031022 nuclear migration along microfilament(GO:0031022)
0.0 0.5 GO:0010265 SCF complex assembly(GO:0010265)
0.0 1.2 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063)
0.0 0.8 GO:0051531 NFAT protein import into nucleus(GO:0051531)
0.0 0.3 GO:0048388 endosomal lumen acidification(GO:0048388)
0.0 0.0 GO:0010700 negative regulation of norepinephrine secretion(GO:0010700)
0.0 0.6 GO:1904936 cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.0 0.3 GO:2000537 regulation of cGMP-mediated signaling(GO:0010752) regulation of B cell chemotaxis(GO:2000537) positive regulation of B cell chemotaxis(GO:2000538)
0.0 1.2 GO:0044342 type B pancreatic cell proliferation(GO:0044342)
0.0 0.5 GO:2000074 regulation of type B pancreatic cell development(GO:2000074)
0.0 0.4 GO:0019896 axonal transport of mitochondrion(GO:0019896)
0.0 0.1 GO:0051902 negative regulation of mitochondrial depolarization(GO:0051902)
0.0 1.5 GO:0042730 fibrinolysis(GO:0042730)
0.0 0.3 GO:0019236 response to pheromone(GO:0019236)
0.0 0.6 GO:0060252 positive regulation of glial cell proliferation(GO:0060252)
0.0 5.3 GO:1900181 negative regulation of protein localization to nucleus(GO:1900181)
0.0 0.2 GO:0061760 antifungal innate immune response(GO:0061760)
0.0 0.8 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.0 0.7 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0 0.5 GO:0006689 ganglioside catabolic process(GO:0006689)
0.0 2.1 GO:0060706 cell differentiation involved in embryonic placenta development(GO:0060706)
0.0 0.3 GO:0008343 adult feeding behavior(GO:0008343)
0.0 0.2 GO:0060005 vestibular reflex(GO:0060005)
0.0 0.3 GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.0 1.5 GO:0035666 TRIF-dependent toll-like receptor signaling pathway(GO:0035666)
0.0 0.3 GO:0045905 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.0 4.6 GO:0022617 extracellular matrix disassembly(GO:0022617)
0.0 0.1 GO:1902683 regulation of receptor localization to synapse(GO:1902683)
0.0 1.8 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.0 0.1 GO:0061056 sclerotome development(GO:0061056)
0.0 0.3 GO:2000767 positive regulation of cytoplasmic translation(GO:2000767)
0.0 8.4 GO:0006906 vesicle fusion(GO:0006906)
0.0 0.1 GO:0046373 arabinose metabolic process(GO:0019566) L-arabinose metabolic process(GO:0046373)
0.0 0.7 GO:0007635 chemosensory behavior(GO:0007635)
0.0 2.1 GO:0000186 activation of MAPKK activity(GO:0000186)
0.0 1.5 GO:0051646 mitochondrion localization(GO:0051646)
0.0 2.0 GO:0070423 nucleotide-binding oligomerization domain containing signaling pathway(GO:0070423)
0.0 1.2 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.0 0.2 GO:2001034 positive regulation of double-strand break repair via nonhomologous end joining(GO:2001034)
0.0 0.1 GO:1903045 neural crest cell migration involved in sympathetic nervous system development(GO:1903045)
0.0 0.6 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)
0.0 0.5 GO:0072189 ureter development(GO:0072189)
0.0 0.2 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
0.0 0.4 GO:0046085 adenosine metabolic process(GO:0046085)
0.0 0.1 GO:0097498 endothelial tube lumen extension(GO:0097498)
0.0 0.2 GO:0021979 hypothalamus cell differentiation(GO:0021979)
0.0 1.1 GO:0050427 purine ribonucleoside bisphosphate metabolic process(GO:0034035) 3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427)
0.0 0.4 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0 0.2 GO:0097116 gephyrin clustering involved in postsynaptic density assembly(GO:0097116)
0.0 0.7 GO:0050832 defense response to fungus(GO:0050832)
0.0 0.2 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.0 1.4 GO:0032784 regulation of DNA-templated transcription, elongation(GO:0032784)
0.0 1.0 GO:0090630 activation of GTPase activity(GO:0090630)
0.0 4.5 GO:0035023 regulation of Rho protein signal transduction(GO:0035023)
0.0 0.1 GO:0042214 terpene metabolic process(GO:0042214)
0.0 1.4 GO:0046580 negative regulation of Ras protein signal transduction(GO:0046580)
0.0 6.8 GO:0016197 endosomal transport(GO:0016197)
0.0 0.1 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.0 0.1 GO:1902268 negative regulation of polyamine transmembrane transport(GO:1902268)
0.0 0.4 GO:0090527 actin filament reorganization(GO:0090527)
0.0 0.5 GO:0036344 platelet formation(GO:0030220) platelet morphogenesis(GO:0036344)
0.0 0.1 GO:0060693 regulation of branching involved in salivary gland morphogenesis(GO:0060693)
0.0 0.1 GO:2001045 negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.0 0.2 GO:0048813 dendrite morphogenesis(GO:0048813)
0.0 0.1 GO:0060029 convergent extension involved in organogenesis(GO:0060029)
0.0 0.3 GO:0071985 multivesicular body sorting pathway(GO:0071985)
0.0 0.2 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
0.0 1.8 GO:0030521 androgen receptor signaling pathway(GO:0030521)
0.0 0.6 GO:0010591 regulation of lamellipodium assembly(GO:0010591)
0.0 0.1 GO:0035494 SNARE complex disassembly(GO:0035494)
0.0 0.2 GO:0007039 protein catabolic process in the vacuole(GO:0007039)
0.0 0.5 GO:0070884 regulation of calcineurin-NFAT signaling cascade(GO:0070884)
0.0 0.3 GO:0060009 Sertoli cell development(GO:0060009)
0.0 0.1 GO:0071918 urea transmembrane transport(GO:0071918)
0.0 0.1 GO:0090107 regulation of high-density lipoprotein particle assembly(GO:0090107)
0.0 1.5 GO:0006305 DNA alkylation(GO:0006305) DNA methylation(GO:0006306)
0.0 0.3 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.0 0.2 GO:0006474 N-terminal protein amino acid acetylation(GO:0006474)
0.0 0.1 GO:0021847 ventricular zone neuroblast division(GO:0021847)
0.0 0.1 GO:0070459 prolactin secretion(GO:0070459)
0.0 0.1 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.0 0.6 GO:0050775 positive regulation of dendrite morphogenesis(GO:0050775)
0.0 0.1 GO:0031532 actin cytoskeleton reorganization(GO:0031532)
0.0 0.2 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.0 0.2 GO:0001502 cartilage condensation(GO:0001502)
0.0 0.5 GO:0006699 bile acid biosynthetic process(GO:0006699)
0.0 0.5 GO:1900740 regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900739) positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900740)
0.0 0.1 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.0 0.2 GO:1903392 negative regulation of focal adhesion assembly(GO:0051895) negative regulation of adherens junction organization(GO:1903392)
0.0 0.2 GO:0015671 oxygen transport(GO:0015671)
0.0 0.3 GO:0033006 regulation of mast cell activation involved in immune response(GO:0033006) regulation of mast cell degranulation(GO:0043304)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 5.0 GO:0043511 inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.9 7.6 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.9 2.6 GO:0005595 collagen type XII trimer(GO:0005595)
0.7 2.9 GO:0060187 cell pole(GO:0060187)
0.6 9.7 GO:0030478 actin cap(GO:0030478)
0.5 3.1 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.5 1.4 GO:0044609 DBIRD complex(GO:0044609)
0.4 21.6 GO:0005605 basal lamina(GO:0005605)
0.4 1.2 GO:0019008 molybdopterin synthase complex(GO:0019008)
0.4 1.2 GO:0008623 CHRAC(GO:0008623)
0.3 1.7 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.3 2.0 GO:0045272 plasma membrane respiratory chain complex I(GO:0045272)
0.3 0.9 GO:0036457 keratohyalin granule(GO:0036457)
0.3 1.4 GO:1990425 ryanodine receptor complex(GO:1990425)
0.3 1.6 GO:0031673 H zone(GO:0031673)
0.3 1.1 GO:0097635 extrinsic component of autophagosome membrane(GO:0097635)
0.3 1.3 GO:0031417 NatC complex(GO:0031417)
0.2 0.7 GO:0034677 integrin alpha7-beta1 complex(GO:0034677)
0.2 0.6 GO:0000806 Y chromosome(GO:0000806)
0.2 2.5 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.2 13.9 GO:0001533 cornified envelope(GO:0001533)
0.2 2.2 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.2 1.2 GO:0070369 Scrib-APC-beta-catenin complex(GO:0034750) beta-catenin-TCF7L2 complex(GO:0070369) catenin-TCF7L2 complex(GO:0071664)
0.2 0.6 GO:0031592 centrosomal corona(GO:0031592)
0.1 1.0 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.1 0.8 GO:1990037 Lewy body core(GO:1990037)
0.1 1.8 GO:0045275 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.1 3.5 GO:0001527 microfibril(GO:0001527) fibril(GO:0043205)
0.1 1.4 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.1 0.9 GO:0005587 collagen type IV trimer(GO:0005587)
0.1 0.6 GO:0031088 platelet dense granule membrane(GO:0031088)
0.1 7.9 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.1 6.7 GO:0043034 costamere(GO:0043034)
0.1 0.9 GO:0070695 FHF complex(GO:0070695)
0.1 2.5 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.1 0.6 GO:0070069 cytochrome complex(GO:0070069)
0.1 0.3 GO:0002944 cyclin K-CDK12 complex(GO:0002944)
0.1 3.6 GO:0070469 respiratory chain(GO:0070469)
0.1 3.3 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.1 0.8 GO:1990578 perinuclear endoplasmic reticulum membrane(GO:1990578)
0.1 0.7 GO:0043541 UDP-N-acetylglucosamine transferase complex(GO:0043541)
0.1 0.9 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.1 5.9 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.1 1.3 GO:0044666 MLL3/4 complex(GO:0044666)
0.1 1.4 GO:0097427 microtubule bundle(GO:0097427)
0.1 1.4 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.1 0.7 GO:0031467 Cul7-RING ubiquitin ligase complex(GO:0031467)
0.1 0.4 GO:0097255 R2TP complex(GO:0097255)
0.1 5.2 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.1 2.0 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.1 1.1 GO:0061700 GATOR2 complex(GO:0061700)
0.1 6.4 GO:0005604 basement membrane(GO:0005604)
0.1 0.8 GO:0097470 ribbon synapse(GO:0097470)
0.1 0.8 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.1 30.0 GO:0000790 nuclear chromatin(GO:0000790)
0.0 1.4 GO:0030014 CCR4-NOT complex(GO:0030014)
0.0 0.5 GO:0005916 fascia adherens(GO:0005916)
0.0 7.0 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 4.9 GO:0035580 specific granule lumen(GO:0035580)
0.0 1.1 GO:0033270 paranode region of axon(GO:0033270)
0.0 5.0 GO:0035577 azurophil granule membrane(GO:0035577)
0.0 0.9 GO:0016461 unconventional myosin complex(GO:0016461)
0.0 0.5 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.0 0.3 GO:0033565 ESCRT-0 complex(GO:0033565)
0.0 0.7 GO:0034518 mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518)
0.0 5.2 GO:0005796 Golgi lumen(GO:0005796)
0.0 0.4 GO:0032584 growth cone membrane(GO:0032584)
0.0 0.9 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.2 GO:0070852 cell body fiber(GO:0070852)
0.0 0.9 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 3.4 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 0.6 GO:0017119 Golgi transport complex(GO:0017119)
0.0 0.4 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 0.3 GO:0035253 ciliary rootlet(GO:0035253)
0.0 0.3 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 1.2 GO:0032432 actin filament bundle(GO:0032432)
0.0 0.7 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.7 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 1.3 GO:0031258 lamellipodium membrane(GO:0031258)
0.0 0.6 GO:0060076 excitatory synapse(GO:0060076)
0.0 0.7 GO:0005686 U2 snRNP(GO:0005686)
0.0 0.3 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.0 9.4 GO:0005770 late endosome(GO:0005770)
0.0 3.9 GO:0035579 specific granule membrane(GO:0035579)
0.0 0.3 GO:0061200 clathrin-sculpted gamma-aminobutyric acid transport vesicle(GO:0061200) clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane(GO:0061202)
0.0 0.1 GO:0031251 PAN complex(GO:0031251)
0.0 2.1 GO:0001726 ruffle(GO:0001726)
0.0 0.3 GO:0005642 annulate lamellae(GO:0005642)
0.0 2.5 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 0.4 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 0.2 GO:0061689 tricellular tight junction(GO:0061689)
0.0 3.8 GO:0043296 apical junction complex(GO:0043296)
0.0 3.0 GO:0031901 early endosome membrane(GO:0031901)
0.0 0.2 GO:0036157 outer dynein arm(GO:0036157)
0.0 0.3 GO:0008091 spectrin(GO:0008091)
0.0 0.3 GO:0097225 sperm midpiece(GO:0097225)
0.0 2.5 GO:0016605 PML body(GO:0016605)
0.0 1.5 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0 0.6 GO:0030686 90S preribosome(GO:0030686)
0.0 0.5 GO:0005639 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.0 0.2 GO:0005721 pericentric heterochromatin(GO:0005721)
0.0 0.9 GO:0031201 SNARE complex(GO:0031201)
0.0 0.6 GO:0005871 kinesin complex(GO:0005871)
0.0 0.0 GO:0000438 core TFIIH complex portion of holo TFIIH complex(GO:0000438)
0.0 1.2 GO:0034707 chloride channel complex(GO:0034707)
0.0 0.9 GO:0005762 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 0.2 GO:0032426 stereocilium tip(GO:0032426)
0.0 0.7 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 0.5 GO:0005811 lipid particle(GO:0005811)
0.0 1.7 GO:0032587 ruffle membrane(GO:0032587)
0.0 0.3 GO:0097440 apical dendrite(GO:0097440)
0.0 2.6 GO:0005802 trans-Golgi network(GO:0005802)
0.0 0.4 GO:0034399 nuclear periphery(GO:0034399)
0.0 2.0 GO:0010008 endosome membrane(GO:0010008)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
2.7 8.0 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
1.0 22.1 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
1.0 4.8 GO:0070576 vitamin D 24-hydroxylase activity(GO:0070576)
0.8 4.7 GO:0070699 type II activin receptor binding(GO:0070699)
0.5 3.5 GO:0005353 fructose transmembrane transporter activity(GO:0005353)
0.4 6.7 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.4 1.6 GO:0031728 CCR3 chemokine receptor binding(GO:0031728)
0.4 7.5 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.4 7.0 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.4 1.4 GO:0005026 transforming growth factor beta receptor activity, type II(GO:0005026)
0.4 1.1 GO:0008441 3'(2'),5'-bisphosphate nucleotidase activity(GO:0008441)
0.3 9.4 GO:0001871 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.3 2.9 GO:0043426 MRF binding(GO:0043426)
0.3 0.9 GO:0060001 minus-end directed microfilament motor activity(GO:0060001)
0.3 1.8 GO:0004882 androgen receptor activity(GO:0004882)
0.3 4.8 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.3 3.0 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.3 0.9 GO:0034875 oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875)
0.3 9.5 GO:0005523 tropomyosin binding(GO:0005523)
0.3 0.8 GO:0086039 lutropin-choriogonadotropic hormone receptor binding(GO:0031775) calcium-transporting ATPase activity involved in regulation of cardiac muscle cell membrane potential(GO:0086039)
0.3 2.1 GO:0008241 peptidyl-dipeptidase activity(GO:0008241)
0.3 1.3 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.2 2.6 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.2 1.4 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.2 5.5 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.2 1.1 GO:0030375 thyroid hormone receptor activator activity(GO:0010861) thyroid hormone receptor coactivator activity(GO:0030375)
0.2 1.8 GO:0016679 oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679)
0.2 14.0 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.2 6.8 GO:0002162 dystroglycan binding(GO:0002162)
0.2 1.0 GO:0016623 oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623)
0.2 2.5 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.2 5.1 GO:0001608 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.2 1.6 GO:0015111 iodide transmembrane transporter activity(GO:0015111)
0.2 1.7 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.2 2.5 GO:0089720 caspase binding(GO:0089720)
0.2 2.1 GO:0030280 structural constituent of epidermis(GO:0030280)
0.2 6.9 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.2 2.5 GO:0005221 intracellular cyclic nucleotide activated cation channel activity(GO:0005221) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.2 1.7 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.2 6.5 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.2 0.8 GO:0003829 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.1 1.0 GO:0070728 leucine binding(GO:0070728)
0.1 0.7 GO:0050509 N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity(GO:0050509)
0.1 1.5 GO:0004022 alcohol dehydrogenase (NAD) activity(GO:0004022)
0.1 3.3 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.1 1.0 GO:0050816 phosphothreonine binding(GO:0050816)
0.1 0.7 GO:0050436 microfibril binding(GO:0050436)
0.1 0.4 GO:0050146 nucleoside phosphotransferase activity(GO:0050146)
0.1 0.9 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.1 0.9 GO:0003983 UTP:glucose-1-phosphate uridylyltransferase activity(GO:0003983) UTP-monosaccharide-1-phosphate uridylyltransferase activity(GO:0051748)
0.1 1.3 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
0.1 0.5 GO:0008260 3-oxoacid CoA-transferase activity(GO:0008260)
0.1 0.3 GO:0004823 leucine-tRNA ligase activity(GO:0004823)
0.1 3.8 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.1 0.3 GO:0016503 pheromone receptor activity(GO:0016503)
0.1 0.3 GO:0015432 bile acid-exporting ATPase activity(GO:0015432)
0.1 6.9 GO:0016504 peptidase activator activity(GO:0016504)
0.1 1.0 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.1 0.5 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.1 0.7 GO:0098639 collagen binding involved in cell-matrix adhesion(GO:0098639)
0.1 0.2 GO:0070506 high-density lipoprotein particle receptor activity(GO:0070506)
0.1 0.3 GO:0047223 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase activity(GO:0047223)
0.1 3.0 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.1 5.1 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.1 0.3 GO:0099609 microtubule lateral binding(GO:0099609)
0.1 2.2 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.1 0.4 GO:0035515 oxidative RNA demethylase activity(GO:0035515)
0.1 0.8 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.1 1.7 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 1.3 GO:0003691 double-stranded telomeric DNA binding(GO:0003691)
0.1 0.5 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.1 0.9 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.1 0.4 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.1 3.4 GO:0030332 cyclin binding(GO:0030332)
0.1 2.3 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.1 1.9 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.1 8.9 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.1 2.4 GO:0051059 NF-kappaB binding(GO:0051059)
0.1 2.6 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.1 1.2 GO:0045294 alpha-catenin binding(GO:0045294)
0.1 0.5 GO:0052794 exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.1 13.3 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.1 1.4 GO:0050321 tau-protein kinase activity(GO:0050321)
0.1 16.6 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.1 1.0 GO:0004791 thioredoxin-disulfide reductase activity(GO:0004791)
0.1 0.3 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.1 1.2 GO:0048156 tau protein binding(GO:0048156)
0.1 0.3 GO:0051033 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.1 2.5 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.1 0.9 GO:0008494 translation activator activity(GO:0008494)
0.0 0.3 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.0 5.4 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 1.6 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.3 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.0 0.9 GO:0000150 recombinase activity(GO:0000150)
0.0 0.3 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.0 1.8 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.0 0.8 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 1.4 GO:0030275 LRR domain binding(GO:0030275)
0.0 1.6 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.2 GO:0046997 oxidoreductase activity, acting on the CH-NH group of donors, flavin as acceptor(GO:0046997)
0.0 0.9 GO:0051400 BH domain binding(GO:0051400)
0.0 2.7 GO:0030507 spectrin binding(GO:0030507)
0.0 2.3 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 1.1 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.0 1.1 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 1.0 GO:0031005 filamin binding(GO:0031005)
0.0 1.6 GO:0005109 frizzled binding(GO:0005109)
0.0 1.5 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 10.5 GO:0030674 protein binding, bridging(GO:0030674)
0.0 1.4 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 1.6 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.0 1.4 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 0.2 GO:0004977 melanocortin receptor activity(GO:0004977)
0.0 0.3 GO:0016778 diphosphotransferase activity(GO:0016778)
0.0 0.6 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0 0.1 GO:0046556 alpha-L-arabinofuranosidase activity(GO:0046556)
0.0 2.9 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 1.4 GO:0001159 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978) core promoter proximal region sequence-specific DNA binding(GO:0000987) core promoter proximal region DNA binding(GO:0001159)
0.0 0.7 GO:0070064 proline-rich region binding(GO:0070064)
0.0 2.6 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 1.0 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 1.4 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
0.0 0.7 GO:0000339 RNA cap binding(GO:0000339)
0.0 1.6 GO:0043621 protein self-association(GO:0043621)
0.0 0.5 GO:0097602 cullin family protein binding(GO:0097602)
0.0 0.7 GO:0070403 NAD+ binding(GO:0070403)
0.0 0.6 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0 0.2 GO:0099529 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.0 1.0 GO:0042605 peptide antigen binding(GO:0042605)
0.0 0.2 GO:0004522 ribonuclease A activity(GO:0004522)
0.0 0.4 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 3.4 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 0.6 GO:0017136 NAD-dependent histone deacetylase activity(GO:0017136) histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041) NAD-dependent protein deacetylase activity(GO:0034979)
0.0 0.0 GO:0034618 arginine binding(GO:0034618)
0.0 0.2 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.0 0.6 GO:0017166 vinculin binding(GO:0017166)
0.0 15.2 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.0 1.1 GO:0032452 histone demethylase activity(GO:0032452)
0.0 0.9 GO:0015248 sterol transporter activity(GO:0015248)
0.0 0.1 GO:0034186 apolipoprotein A-I binding(GO:0034186)
0.0 1.6 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.1 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.0 0.9 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.2 GO:0030957 Tat protein binding(GO:0030957)
0.0 1.1 GO:0050699 WW domain binding(GO:0050699)
0.0 0.4 GO:0008391 arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392)
0.0 0.4 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.9 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 0.2 GO:0070628 proteasome binding(GO:0070628)
0.0 0.2 GO:0033038 bitter taste receptor activity(GO:0033038)
0.0 1.4 GO:0034212 peptide N-acetyltransferase activity(GO:0034212)
0.0 0.3 GO:0042923 neuropeptide binding(GO:0042923)
0.0 0.8 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0 0.6 GO:0001972 retinoic acid binding(GO:0001972)
0.0 0.3 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0 0.7 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.0 0.3 GO:0015643 toxic substance binding(GO:0015643)
0.0 0.5 GO:0015485 cholesterol binding(GO:0015485)
0.0 0.4 GO:0017160 Ral GTPase binding(GO:0017160)
0.0 2.8 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 0.3 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.5 GO:0000983 transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
0.0 0.1 GO:0015265 urea channel activity(GO:0015265)
0.0 0.0 GO:0001515 opioid peptide activity(GO:0001515)
0.0 0.1 GO:0019870 potassium channel inhibitor activity(GO:0019870)
0.0 0.5 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 1.7 GO:0036459 thiol-dependent ubiquitinyl hydrolase activity(GO:0036459)
0.0 0.2 GO:0072509 calcium-transporting ATPase activity(GO:0005388) calcium ion transmembrane transporter activity(GO:0015085) divalent inorganic cation transmembrane transporter activity(GO:0072509)
0.0 0.4 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0 0.5 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 0.2 GO:0008381 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.0 0.1 GO:0043237 laminin-1 binding(GO:0043237)
0.0 0.5 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 30.4 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.3 1.5 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.1 26.5 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.1 1.7 ST STAT3 PATHWAY STAT3 Pathway
0.1 2.2 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.1 7.4 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.1 8.3 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.1 8.2 PID FOXO PATHWAY FoxO family signaling
0.1 9.5 PID NOTCH PATHWAY Notch signaling pathway
0.1 1.0 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.1 7.5 PID LKB1 PATHWAY LKB1 signaling events
0.1 21.2 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1 2.1 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.1 1.6 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 1.5 PID PS1 PATHWAY Presenilin action in Notch and Wnt signaling
0.0 2.1 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.0 0.8 PID IL5 PATHWAY IL5-mediated signaling events
0.0 1.5 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0 5.0 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 1.5 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.0 5.3 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 1.7 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 3.0 PID IL4 2PATHWAY IL4-mediated signaling events
0.0 13.2 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.3 ST GAQ PATHWAY G alpha q Pathway
0.0 0.9 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.0 2.0 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 2.0 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 4.2 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 0.7 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.0 0.9 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 0.7 ST GA12 PATHWAY G alpha 12 Pathway
0.0 8.3 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.6 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.0 2.4 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 0.5 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 0.4 PID IL27 PATHWAY IL27-mediated signaling events
0.0 1.2 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.0 0.6 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 0.7 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 0.6 PID IL2 1PATHWAY IL2-mediated signaling events
0.0 0.7 PID EPHB FWD PATHWAY EPHB forward signaling
0.0 0.5 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 0.6 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 0.5 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 0.9 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 1.2 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.0 0.2 PID ALK1 PATHWAY ALK1 signaling events
0.0 0.1 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.0 0.3 PID NCADHERIN PATHWAY N-cadherin signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 5.0 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.4 21.9 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.3 6.0 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.3 5.7 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.2 0.9 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.2 8.0 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.1 2.0 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.1 2.5 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.1 12.5 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.1 10.0 REACTOME MYOGENESIS Genes involved in Myogenesis
0.1 3.5 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.1 4.3 REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.1 6.4 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.1 1.7 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.1 3.7 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.1 2.0 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.1 0.8 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.1 2.3 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.1 2.2 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.1 1.3 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.1 0.7 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.1 2.4 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 0.9 REACTOME SIGNALLING TO P38 VIA RIT AND RIN Genes involved in Signalling to p38 via RIT and RIN
0.0 1.5 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 1.1 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 1.0 REACTOME ACTIVATED POINT MUTANTS OF FGFR2 Genes involved in Activated point mutants of FGFR2
0.0 0.9 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 1.4 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.0 0.7 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.0 1.3 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.0 0.9 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.0 0.8 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 2.2 REACTOME INTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.0 1.3 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.5 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.0 1.9 REACTOME EXTRACELLULAR MATRIX ORGANIZATION Genes involved in Extracellular matrix organization
0.0 3.4 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.0 1.1 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 2.9 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 1.4 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0 0.8 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 2.3 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.0 0.4 REACTOME NRIF SIGNALS CELL DEATH FROM THE NUCLEUS Genes involved in NRIF signals cell death from the nucleus
0.0 0.3 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 1.1 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.4 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.0 0.5 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 0.7 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 1.0 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.5 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.0 0.9 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 0.5 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.7 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.9 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 1.6 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 1.7 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.9 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.4 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
0.0 0.3 REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.0 1.5 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 1.6 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 1.1 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.0 0.3 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
0.0 0.6 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.3 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 1.5 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.0 0.9 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport