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SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for HOXC12_HOXD12

Z-value: 0.92

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Transcription factors associated with HOXC12_HOXD12

Gene Symbol Gene ID Gene Info
HOXC12
ENSG00000123407.3 homeobox C12
HOXD12
ENSG00000170178.5 homeobox D12

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HOXC12hg19_v2_chr12_+_54348618_543486930.126.2e-01Click!
HOXD12hg19_v2_chr2_+_176964458_176964540-0.087.5e-01Click!

Activity profile of HOXC12_HOXD12 motif

Sorted Z-values of HOXC12_HOXD12 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr1_-_220219775 2.82 ENST00000609181.1
EPRS
glutamyl-prolyl-tRNA synthetase
chr13_+_53029564 1.60 ENST00000468284.1
ENST00000378034.3
ENST00000258607.5
ENST00000378037.5
CKAP2
cytoskeleton associated protein 2
chr22_-_36925124 1.47 ENST00000457241.1
EIF3D
eukaryotic translation initiation factor 3, subunit D
chr13_+_53030107 1.28 ENST00000490903.1
ENST00000480747.1
CKAP2
cytoskeleton associated protein 2
chr11_+_111896090 1.20 ENST00000393051.1
DLAT
dihydrolipoamide S-acetyltransferase
chr11_+_111896320 1.20 ENST00000531306.1
ENST00000537636.1
DLAT
dihydrolipoamide S-acetyltransferase
chr3_+_99979828 1.14 ENST00000485687.1
ENST00000344949.5
ENST00000394144.4
TBC1D23
TBC1 domain family, member 23
chr1_-_220220000 1.09 ENST00000366923.3
EPRS
glutamyl-prolyl-tRNA synthetase
chr4_-_39367949 0.99 ENST00000503784.1
ENST00000349703.2
ENST00000381897.1
RFC1
replication factor C (activator 1) 1, 145kDa
chr18_-_812517 0.96 ENST00000584307.1
YES1
v-yes-1 Yamaguchi sarcoma viral oncogene homolog 1
chr12_+_6603253 0.93 ENST00000382457.4
ENST00000545962.1
NCAPD2
non-SMC condensin I complex, subunit D2
chr5_+_169011033 0.89 ENST00000513795.1
SPDL1
spindle apparatus coiled-coil protein 1
chr5_-_39270725 0.82 ENST00000512138.1
ENST00000512982.1
ENST00000540520.1
FYB
FYN binding protein
chr1_-_156307992 0.81 ENST00000415548.1
CCT3
chaperonin containing TCP1, subunit 3 (gamma)
chr10_-_98347063 0.80 ENST00000443638.1
TM9SF3
transmembrane 9 superfamily member 3
chr5_+_169010638 0.79 ENST00000265295.4
ENST00000506574.1
ENST00000515224.1
ENST00000508247.1
ENST00000513941.1
SPDL1
spindle apparatus coiled-coil protein 1
chr14_+_31028348 0.78 ENST00000550944.1
ENST00000438909.2
ENST00000553504.1
G2E3
G2/M-phase specific E3 ubiquitin protein ligase
chr8_+_101170563 0.77 ENST00000520508.1
ENST00000388798.2
SPAG1
sperm associated antigen 1
chr3_-_17783990 0.75 ENST00000429383.4
ENST00000446863.1
ENST00000414349.1
ENST00000428355.1
ENST00000425944.1
ENST00000445294.1
ENST00000444471.1
ENST00000415814.2
TBC1D5
TBC1 domain family, member 5
chr6_-_56716686 0.74 ENST00000520645.1
DST
dystonin
chr6_+_106988986 0.73 ENST00000457437.1
ENST00000535438.1
AIM1
absent in melanoma 1
chr7_-_35013217 0.71 ENST00000446375.1
DPY19L1
dpy-19-like 1 (C. elegans)
chr22_-_36924944 0.69 ENST00000405442.1
ENST00000402116.1
EIF3D
eukaryotic translation initiation factor 3, subunit D
chr1_-_155948890 0.66 ENST00000471589.1
ARHGEF2
Rho/Rac guanine nucleotide exchange factor (GEF) 2
chr22_+_38035623 0.66 ENST00000336738.5
ENST00000442465.2
SH3BP1
SH3-domain binding protein 1
chr3_-_25706368 0.66 ENST00000424225.1
TOP2B
topoisomerase (DNA) II beta 180kDa
chr7_+_64838712 0.63 ENST00000328747.7
ENST00000431504.1
ENST00000357512.2
ZNF92
zinc finger protein 92
chr17_+_29664830 0.61 ENST00000444181.2
ENST00000417592.2
NF1
neurofibromin 1
chr8_+_94710789 0.55 ENST00000523475.1
FAM92A1
family with sequence similarity 92, member A1
chr22_-_36925186 0.53 ENST00000541106.1
ENST00000455547.1
ENST00000432675.1
EIF3D
eukaryotic translation initiation factor 3, subunit D
chr15_+_79166065 0.53 ENST00000559690.1
ENST00000559158.1
MORF4L1
mortality factor 4 like 1
chr12_-_88535747 0.53 ENST00000309041.7
CEP290
centrosomal protein 290kDa
chr15_-_71184724 0.52 ENST00000560604.1
THAP10
THAP domain containing 10
chr16_-_66907139 0.52 ENST00000561579.2
NAE1
NEDD8 activating enzyme E1 subunit 1
chr2_+_172778952 0.51 ENST00000392584.1
ENST00000264108.4
HAT1
histone acetyltransferase 1
chr15_+_66797627 0.50 ENST00000565627.1
ENST00000564179.1
ZWILCH
zwilch kinetochore protein
chr15_+_78441663 0.48 ENST00000299518.2
ENST00000558554.1
ENST00000557826.1
ENST00000561279.1
ENST00000559186.1
ENST00000560770.1
ENST00000559881.1
ENST00000559205.1
ENST00000441490.2
IDH3A
isocitrate dehydrogenase 3 (NAD+) alpha
chr7_+_64838786 0.46 ENST00000450302.2
ZNF92
zinc finger protein 92
chr10_-_52383644 0.45 ENST00000361781.2
SGMS1
sphingomyelin synthase 1
chr5_-_176433693 0.44 ENST00000507513.1
ENST00000511320.1
UIMC1
ubiquitin interaction motif containing 1
chr3_+_99986036 0.44 ENST00000471098.1
TBC1D23
TBC1 domain family, member 23
chr12_-_122879969 0.43 ENST00000540304.1
CLIP1
CAP-GLY domain containing linker protein 1
chr19_-_40790729 0.43 ENST00000423127.1
ENST00000583859.1
ENST00000456441.1
ENST00000452077.1
AKT2
v-akt murine thymoma viral oncogene homolog 2
chr4_+_106631966 0.42 ENST00000360505.5
ENST00000510865.1
ENST00000509336.1
GSTCD
glutathione S-transferase, C-terminal domain containing
chr4_+_47487285 0.42 ENST00000273859.3
ENST00000504445.1
ATP10D
ATPase, class V, type 10D
chr22_+_38035459 0.41 ENST00000357436.4
SH3BP1
SH3-domain binding protein 1
chr19_+_11200038 0.41 ENST00000558518.1
ENST00000557933.1
ENST00000455727.2
ENST00000535915.1
ENST00000545707.1
ENST00000558013.1
LDLR
low density lipoprotein receptor
chr10_+_31608054 0.41 ENST00000320985.10
ENST00000361642.5
ENST00000560721.2
ENST00000558440.1
ENST00000424869.1
ENST00000542815.3
ZEB1
zinc finger E-box binding homeobox 1
chr17_-_42767092 0.41 ENST00000588687.1
CCDC43
coiled-coil domain containing 43
chr18_-_46895066 0.40 ENST00000583225.1
ENST00000584983.1
ENST00000583280.1
ENST00000581738.1
DYM
dymeclin
chr6_-_27782548 0.40 ENST00000333151.3
HIST1H2AJ
histone cluster 1, H2aj
chr3_-_196911002 0.39 ENST00000452595.1
DLG1
discs, large homolog 1 (Drosophila)
chr17_+_56769924 0.39 ENST00000461271.1
ENST00000583539.1
ENST00000337432.4
ENST00000421782.2
RAD51C
RAD51 paralog C
chr14_+_67291158 0.39 ENST00000555456.1
GPHN
gephyrin
chr19_+_18668616 0.39 ENST00000600372.1
KXD1
KxDL motif containing 1
chr17_+_17685422 0.38 ENST00000395774.1
RAI1
retinoic acid induced 1
chr15_-_72514866 0.38 ENST00000562997.1
PKM
pyruvate kinase, muscle
chr12_+_54384370 0.38 ENST00000504315.1
HOXC6
homeobox C6
chr13_-_79233314 0.37 ENST00000282003.6
RNF219
ring finger protein 219
chr16_-_18908196 0.36 ENST00000565324.1
ENST00000561947.1
SMG1
SMG1 phosphatidylinositol 3-kinase-related kinase
chr22_+_29168652 0.36 ENST00000249064.4
ENST00000444523.1
ENST00000448492.2
ENST00000421503.2
CCDC117
coiled-coil domain containing 117
chr9_+_137979506 0.36 ENST00000539529.1
ENST00000392991.4
ENST00000371793.3
OLFM1
olfactomedin 1
chr8_+_27950619 0.36 ENST00000542181.1
ENST00000524103.1
ENST00000537665.1
ENST00000380353.4
ENST00000520288.1
ELP3
elongator acetyltransferase complex subunit 3
chr5_-_65018834 0.35 ENST00000506816.1
SGTB
small glutamine-rich tetratricopeptide repeat (TPR)-containing, beta
chr12_-_49523896 0.34 ENST00000549870.1
TUBA1B
tubulin, alpha 1b
chr1_-_26231589 0.34 ENST00000374291.1
STMN1
stathmin 1
chr4_+_70894130 0.34 ENST00000526767.1
ENST00000530128.1
ENST00000381057.3
HTN3
histatin 3
chr16_+_66914264 0.34 ENST00000311765.2
ENST00000568869.1
ENST00000561704.1
ENST00000568398.1
ENST00000566776.1
PDP2
pyruvate dehyrogenase phosphatase catalytic subunit 2
chr9_+_2029019 0.33 ENST00000382194.1
SMARCA2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr17_+_34890807 0.33 ENST00000429467.2
ENST00000592983.1
PIGW
phosphatidylinositol glycan anchor biosynthesis, class W
chr8_+_17013515 0.33 ENST00000262096.8
ZDHHC2
zinc finger, DHHC-type containing 2
chr12_+_32832203 0.33 ENST00000553257.1
ENST00000549701.1
ENST00000358214.5
ENST00000266481.6
ENST00000551476.1
ENST00000550154.1
ENST00000547312.1
ENST00000414834.2
ENST00000381000.4
ENST00000548750.1
DNM1L
dynamin 1-like
chr21_-_28215332 0.33 ENST00000517777.1
ADAMTS1
ADAM metallopeptidase with thrombospondin type 1 motif, 1
chr17_-_15496722 0.33 ENST00000472534.1
CDRT1
CMT1A duplicated region transcript 1
chr11_+_33278811 0.33 ENST00000303296.4
ENST00000379016.3
HIPK3
homeodomain interacting protein kinase 3
chr7_+_94536514 0.33 ENST00000413325.1
PPP1R9A
protein phosphatase 1, regulatory subunit 9A
chr3_+_32737027 0.33 ENST00000454516.2
CNOT10
CCR4-NOT transcription complex, subunit 10
chr19_+_21265028 0.33 ENST00000291770.7
ZNF714
zinc finger protein 714
chr13_+_34392200 0.33 ENST00000434425.1
RFC3
replication factor C (activator 1) 3, 38kDa
chr1_-_146989697 0.33 ENST00000437831.1
LINC00624
long intergenic non-protein coding RNA 624
chr3_+_179322573 0.33 ENST00000493866.1
ENST00000472629.1
ENST00000482604.1
NDUFB5
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5, 16kDa
chr9_+_125703282 0.33 ENST00000373647.4
ENST00000402311.1
RABGAP1
RAB GTPase activating protein 1
chrX_-_48326764 0.32 ENST00000413668.1
ENST00000441948.1
SLC38A5
solute carrier family 38, member 5
chr14_+_55494323 0.32 ENST00000339298.2
SOCS4
suppressor of cytokine signaling 4
chr4_-_114682224 0.32 ENST00000342666.5
ENST00000515496.1
ENST00000514328.1
ENST00000508738.1
ENST00000379773.2
CAMK2D
calcium/calmodulin-dependent protein kinase II delta
chr12_+_10658201 0.31 ENST00000322446.3
EIF2S3L
Putative eukaryotic translation initiation factor 2 subunit 3-like protein
chr4_-_111120334 0.31 ENST00000503885.1
ELOVL6
ELOVL fatty acid elongase 6
chr11_-_104480019 0.31 ENST00000536529.1
ENST00000545630.1
ENST00000538641.1
RP11-886D15.1
RP11-886D15.1
chr20_+_19870167 0.31 ENST00000440354.2
RIN2
Ras and Rab interactor 2
chr13_+_34392185 0.31 ENST00000380071.3
RFC3
replication factor C (activator 1) 3, 38kDa
chr8_-_82608409 0.31 ENST00000518568.1
SLC10A5
solute carrier family 10, member 5
chr11_-_107729504 0.31 ENST00000265836.7
SLC35F2
solute carrier family 35, member F2
chr19_-_23869999 0.30 ENST00000601935.1
ENST00000359788.4
ENST00000600313.1
ENST00000596211.1
ENST00000599168.1
ZNF675
zinc finger protein 675
chr19_+_21264980 0.30 ENST00000596053.1
ENST00000597086.1
ENST00000596143.1
ENST00000596367.1
ENST00000601416.1
ZNF714
zinc finger protein 714
chr11_-_107328527 0.30 ENST00000282251.5
ENST00000433523.1
CWF19L2
CWF19-like 2, cell cycle control (S. pombe)
chr14_-_35591156 0.30 ENST00000554361.1
PPP2R3C
protein phosphatase 2, regulatory subunit B'', gamma
chr14_-_50319482 0.30 ENST00000546046.1
ENST00000555970.1
ENST00000554626.1
ENST00000545773.1
ENST00000556672.1
NEMF
nuclear export mediator factor
chr16_+_67143828 0.30 ENST00000563853.2
ENST00000569914.1
ENST00000569600.1
C16orf70
chromosome 16 open reading frame 70
chr10_+_12238171 0.29 ENST00000378900.2
ENST00000442050.1
CDC123
cell division cycle 123
chr9_+_115513003 0.29 ENST00000374232.3
SNX30
sorting nexin family member 30
chr6_-_10694766 0.29 ENST00000460742.2
ENST00000259983.3
ENST00000379586.1
C6orf52
chromosome 6 open reading frame 52
chr14_+_21359558 0.29 ENST00000304639.3
RNASE3
ribonuclease, RNase A family, 3
chr1_+_100818009 0.29 ENST00000370125.2
ENST00000361544.6
ENST00000370124.3
CDC14A
cell division cycle 14A
chr9_-_88896977 0.28 ENST00000311534.6
ISCA1
iron-sulfur cluster assembly 1
chr4_+_110354928 0.28 ENST00000504968.2
ENST00000399100.2
ENST00000265175.5
SEC24B
SEC24 family member B
chr5_-_146833222 0.28 ENST00000534907.1
DPYSL3
dihydropyrimidinase-like 3
chr4_-_17513604 0.28 ENST00000505710.1
QDPR
quinoid dihydropteridine reductase
chr14_-_50319758 0.28 ENST00000298310.5
NEMF
nuclear export mediator factor
chr13_-_46543805 0.28 ENST00000378921.2
ZC3H13
zinc finger CCCH-type containing 13
chr11_-_107729287 0.28 ENST00000375682.4
SLC35F2
solute carrier family 35, member F2
chr10_-_27443294 0.28 ENST00000396296.3
ENST00000375972.3
ENST00000376016.3
ENST00000491542.2
YME1L1
YME1-like 1 ATPase
chr5_-_146833485 0.28 ENST00000398514.3
DPYSL3
dihydropyrimidinase-like 3
chr4_-_111120132 0.28 ENST00000506625.1
ELOVL6
ELOVL fatty acid elongase 6
chr12_-_31743901 0.28 ENST00000354285.4
DENND5B
DENN/MADD domain containing 5B
chr2_-_225811747 0.27 ENST00000409592.3
DOCK10
dedicator of cytokinesis 10
chr1_-_247242048 0.27 ENST00000366503.2
ZNF670
zinc finger protein 670
chr4_+_169842707 0.27 ENST00000503290.1
PALLD
palladin, cytoskeletal associated protein
chr4_-_156298087 0.27 ENST00000311277.4
MAP9
microtubule-associated protein 9
chrX_-_48326683 0.27 ENST00000440085.1
SLC38A5
solute carrier family 38, member 5
chr15_+_66797455 0.26 ENST00000446801.2
ZWILCH
zwilch kinetochore protein
chr14_+_90422239 0.26 ENST00000393452.3
ENST00000554180.1
ENST00000393454.2
ENST00000553617.1
ENST00000335725.4
ENST00000357382.3
ENST00000556867.1
ENST00000553527.1
TDP1
tyrosyl-DNA phosphodiesterase 1
chr10_-_113943447 0.26 ENST00000369425.1
ENST00000348367.4
ENST00000423155.1
GPAM
glycerol-3-phosphate acyltransferase, mitochondrial
chr6_+_126221034 0.26 ENST00000433571.1
NCOA7
nuclear receptor coactivator 7
chr22_+_22676808 0.26 ENST00000390290.2
IGLV1-51
immunoglobulin lambda variable 1-51
chr6_-_131321863 0.26 ENST00000528282.1
EPB41L2
erythrocyte membrane protein band 4.1-like 2
chr11_-_102668879 0.26 ENST00000315274.6
MMP1
matrix metallopeptidase 1 (interstitial collagenase)
chr12_-_30848914 0.26 ENST00000256079.4
IPO8
importin 8
chr2_+_74056066 0.26 ENST00000339566.3
ENST00000409707.1
ENST00000452725.1
ENST00000432295.2
ENST00000424659.1
ENST00000394073.1
STAMBP
STAM binding protein
chr5_+_93954358 0.26 ENST00000504099.1
ANKRD32
ankyrin repeat domain 32
chr15_+_101459420 0.25 ENST00000388948.3
ENST00000284395.5
ENST00000534045.1
ENST00000532029.2
LRRK1
leucine-rich repeat kinase 1
chr1_+_178694300 0.25 ENST00000367635.3
RALGPS2
Ral GEF with PH domain and SH3 binding motif 2
chr4_-_103790026 0.25 ENST00000338145.3
ENST00000357194.6
UBE2D3
ubiquitin-conjugating enzyme E2D 3
chr7_+_152456829 0.24 ENST00000377776.3
ENST00000256001.8
ENST00000397282.2
ACTR3B
ARP3 actin-related protein 3 homolog B (yeast)
chr6_+_30539153 0.24 ENST00000326195.8
ENST00000376545.3
ENST00000396515.4
ENST00000441867.1
ENST00000468958.1
ABCF1
ATP-binding cassette, sub-family F (GCN20), member 1
chr12_+_67663056 0.24 ENST00000545606.1
CAND1
cullin-associated and neddylation-dissociated 1
chr13_+_52586517 0.24 ENST00000523764.1
ENST00000521508.1
ALG11
ALG11, alpha-1,2-mannosyltransferase
chr6_-_166796461 0.24 ENST00000360961.6
ENST00000341756.6
MPC1
mitochondrial pyruvate carrier 1
chr3_+_118905564 0.24 ENST00000460625.1
UPK1B
uroplakin 1B
chr12_+_32832134 0.24 ENST00000452533.2
DNM1L
dynamin 1-like
chr15_+_40674920 0.24 ENST00000416151.2
ENST00000249776.8
KNSTRN
kinetochore-localized astrin/SPAG5 binding protein
chr10_+_12237924 0.24 ENST00000429258.2
ENST00000281141.4
CDC123
cell division cycle 123
chr19_-_48753028 0.23 ENST00000522431.1
CARD8
caspase recruitment domain family, member 8
chr2_+_173955327 0.23 ENST00000422149.1
MLTK
Mitogen-activated protein kinase kinase kinase MLT
chr7_-_151330218 0.23 ENST00000476632.1
PRKAG2
protein kinase, AMP-activated, gamma 2 non-catalytic subunit
chr21_-_27423339 0.23 ENST00000415997.1
APP
amyloid beta (A4) precursor protein
chr2_-_37501692 0.23 ENST00000443977.1
PRKD3
protein kinase D3
chr17_-_74351010 0.23 ENST00000435555.2
PRPSAP1
phosphoribosyl pyrophosphate synthetase-associated protein 1
chr3_+_143690640 0.22 ENST00000315691.3
C3orf58
chromosome 3 open reading frame 58
chr13_+_49551020 0.22 ENST00000541916.1
FNDC3A
fibronectin type III domain containing 3A
chr22_-_38239808 0.22 ENST00000406423.1
ENST00000424350.1
ENST00000458278.2
ANKRD54
ankyrin repeat domain 54
chr15_+_72410629 0.22 ENST00000340912.4
ENST00000544171.1
SENP8
SUMO/sentrin specific peptidase family member 8
chr19_-_44905741 0.22 ENST00000591679.1
ENST00000544719.2
ENST00000330997.4
ENST00000585868.1
ENST00000588212.1
ZNF285
CTC-512J12.6
zinc finger protein 285
Uncharacterized protein
chr3_-_14166316 0.22 ENST00000396914.3
ENST00000295767.5
CHCHD4
coiled-coil-helix-coiled-coil-helix domain containing 4
chr1_-_101491319 0.22 ENST00000342173.7
ENST00000488176.1
ENST00000370109.3
DPH5
diphthamide biosynthesis 5
chr13_-_30160925 0.22 ENST00000450494.1
SLC7A1
solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
chr6_+_26199737 0.22 ENST00000359985.1
HIST1H2BF
histone cluster 1, H2bf
chr1_+_19967014 0.22 ENST00000428975.1
NBL1
neuroblastoma 1, DAN family BMP antagonist
chr17_+_71228793 0.22 ENST00000426147.2
C17orf80
chromosome 17 open reading frame 80
chr2_+_161993465 0.21 ENST00000457476.1
TANK
TRAF family member-associated NFKB activator
chr10_+_124913930 0.21 ENST00000368858.5
BUB3
BUB3 mitotic checkpoint protein
chr1_-_147599549 0.21 ENST00000369228.5
NBPF24
neuroblastoma breakpoint family, member 24
chr3_+_179322481 0.21 ENST00000259037.3
NDUFB5
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5, 16kDa
chr5_+_135468516 0.21 ENST00000507118.1
ENST00000511116.1
ENST00000545279.1
ENST00000545620.1
SMAD5
SMAD family member 5
chr3_+_41241596 0.21 ENST00000450969.1
CTNNB1
catenin (cadherin-associated protein), beta 1, 88kDa
chr3_+_138327542 0.21 ENST00000360570.3
ENST00000393035.2
FAIM
Fas apoptotic inhibitory molecule
chr12_+_28299014 0.21 ENST00000538586.1
ENST00000536154.1
CCDC91
coiled-coil domain containing 91
chr2_-_201753717 0.21 ENST00000409264.2
PPIL3
peptidylprolyl isomerase (cyclophilin)-like 3
chr4_-_74088800 0.20 ENST00000509867.2
ANKRD17
ankyrin repeat domain 17
chr12_+_123259063 0.20 ENST00000392441.4
ENST00000539171.1
CCDC62
coiled-coil domain containing 62
chr5_+_154135453 0.20 ENST00000517616.1
ENST00000518892.1
LARP1
La ribonucleoprotein domain family, member 1
chr12_-_15114603 0.20 ENST00000228945.4
ARHGDIB
Rho GDP dissociation inhibitor (GDI) beta
chrX_+_70503526 0.20 ENST00000413858.1
ENST00000450092.1
NONO
non-POU domain containing, octamer-binding
chr2_+_217277137 0.20 ENST00000430374.1
ENST00000357276.4
ENST00000444508.1
SMARCAL1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1
chr10_+_124913793 0.20 ENST00000368865.4
ENST00000538238.1
ENST00000368859.2
BUB3
BUB3 mitotic checkpoint protein
chr2_+_201450591 0.20 ENST00000374700.2
AOX1
aldehyde oxidase 1
chr2_-_201753859 0.20 ENST00000409361.1
ENST00000392283.4
PPIL3
peptidylprolyl isomerase (cyclophilin)-like 3
chr20_+_5931497 0.19 ENST00000378886.2
ENST00000265187.4
MCM8
minichromosome maintenance complex component 8
chr4_-_176828307 0.19 ENST00000513365.1
ENST00000513667.1
ENST00000503563.1
GPM6A
glycoprotein M6A
chr15_+_77224045 0.19 ENST00000320963.5
ENST00000394883.3
RCN2
reticulocalbin 2, EF-hand calcium binding domain
chr2_-_225362533 0.19 ENST00000451538.1
CUL3
cullin 3
chr19_+_21106081 0.19 ENST00000300540.3
ENST00000595854.1
ENST00000601284.1
ENST00000328178.8
ENST00000599885.1
ENST00000596476.1
ENST00000345030.6
ZNF85
zinc finger protein 85
chr7_+_90012986 0.19 ENST00000416322.1
CLDN12
claudin 12
chr10_-_27529486 0.19 ENST00000375888.1
ACBD5
acyl-CoA binding domain containing 5
chr3_-_131221790 0.19 ENST00000512877.1
ENST00000264995.3
ENST00000511168.1
ENST00000425847.2
MRPL3
mitochondrial ribosomal protein L3
chr16_+_84875609 0.19 ENST00000563066.1
CRISPLD2
cysteine-rich secretory protein LCCL domain containing 2
chr17_-_8286484 0.19 ENST00000582556.1
ENST00000584164.1
ENST00000293842.5
ENST00000584343.1
ENST00000578812.1
ENST00000583011.1
RPL26
ribosomal protein L26
chr8_+_1993173 0.19 ENST00000523438.1
MYOM2
myomesin 2
chr19_-_43708378 0.19 ENST00000599746.1
PSG4
pregnancy specific beta-1-glycoprotein 4
chr3_-_179322416 0.18 ENST00000259038.2
MRPL47
mitochondrial ribosomal protein L47
chr4_-_114682326 0.18 ENST00000505990.1
CAMK2D
calcium/calmodulin-dependent protein kinase II delta
chr13_+_111855414 0.18 ENST00000375737.5
ARHGEF7
Rho guanine nucleotide exchange factor (GEF) 7
chr16_+_20911174 0.18 ENST00000568663.1
LYRM1
LYR motif containing 1
chr17_-_42976736 0.18 ENST00000591382.1
ENST00000593072.1
ENST00000592576.1
ENST00000402521.3
EFTUD2
elongation factor Tu GTP binding domain containing 2
chr10_-_99052382 0.18 ENST00000453547.2
ENST00000316676.8
ENST00000358308.3
ENST00000466484.1
ENST00000358531.4
ARHGAP19-SLIT1
ARHGAP19
ARHGAP19-SLIT1 readthrough (NMD candidate)
Rho GTPase activating protein 19
chr11_-_119991589 0.18 ENST00000526881.1
TRIM29
tripartite motif containing 29
chr5_-_146781153 0.18 ENST00000520473.1
DPYSL3
dihydropyrimidinase-like 3
chr9_+_15553055 0.18 ENST00000380701.3
CCDC171
coiled-coil domain containing 171
chr8_-_38008783 0.17 ENST00000276449.4
STAR
steroidogenic acute regulatory protein
chr1_-_71546690 0.17 ENST00000254821.6
ZRANB2
zinc finger, RAN-binding domain containing 2
chr7_-_3214287 0.17 ENST00000404626.3
AC091801.1
LOC392621; Uncharacterized protein

Network of associatons between targets according to the STRING database.

First level regulatory network of HOXC12_HOXD12

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 3.9 GO:0006433 glutamyl-tRNA aminoacylation(GO:0006424) prolyl-tRNA aminoacylation(GO:0006433)
0.7 2.7 GO:0001732 formation of cytoplasmic translation initiation complex(GO:0001732)
0.2 0.6 GO:0061534 gamma-aminobutyric acid secretion, neurotransmission(GO:0061534)
0.2 0.6 GO:0036466 synaptic vesicle recycling via endosome(GO:0036466)
0.2 0.5 GO:0042040 molybdenum incorporation into molybdenum-molybdopterin complex(GO:0018315) metal incorporation into metallo-molybdopterin complex(GO:0042040) glycine receptor clustering(GO:0072579)
0.1 2.7 GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
0.1 0.4 GO:1903979 negative regulation of microglial cell activation(GO:1903979)
0.1 0.3 GO:1901301 regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.1 0.7 GO:0071802 negative regulation of podosome assembly(GO:0071802)
0.1 0.3 GO:1904049 negative regulation of spontaneous neurotransmitter secretion(GO:1904049)
0.1 0.6 GO:1900264 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.1 1.5 GO:0034501 protein localization to kinetochore(GO:0034501)
0.1 0.9 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.1 0.2 GO:0089700 protein kinase D signaling(GO:0089700)
0.1 0.2 GO:0045041 protein import into mitochondrial intermembrane space(GO:0045041)
0.1 2.9 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026)
0.1 0.5 GO:0071461 cellular response to redox state(GO:0071461)
0.1 0.4 GO:0051177 meiotic sister chromatid cohesion(GO:0051177)
0.1 0.7 GO:0018211 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.1 0.4 GO:0044861 protein transport into plasma membrane raft(GO:0044861)
0.1 0.4 GO:0071486 cellular response to high light intensity(GO:0071486) retinal rod cell apoptotic process(GO:0097473)
0.1 0.2 GO:0006086 acetyl-CoA biosynthetic process from pyruvate(GO:0006086)
0.1 0.2 GO:0014016 neuroblast differentiation(GO:0014016)
0.1 0.6 GO:0019368 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.1 0.2 GO:1904499 glial cell fate determination(GO:0007403) canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation(GO:0061324) regulation of chromatin-mediated maintenance of transcription(GO:1904499) positive regulation of chromatin-mediated maintenance of transcription(GO:1904501) regulation of euchromatin binding(GO:1904793)
0.1 0.3 GO:0051563 smooth endoplasmic reticulum calcium ion homeostasis(GO:0051563)
0.0 0.2 GO:0046110 xanthine metabolic process(GO:0046110)
0.0 0.3 GO:1905098 negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098)
0.0 0.8 GO:1904871 regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871)
0.0 0.5 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0 0.1 GO:0021503 neural fold bending(GO:0021503)
0.0 0.7 GO:0008090 retrograde axonal transport(GO:0008090)
0.0 0.4 GO:0045602 negative regulation of endothelial cell differentiation(GO:0045602)
0.0 0.2 GO:0018963 insecticide metabolic process(GO:0017143) phthalate metabolic process(GO:0018963) cellular response to luteinizing hormone stimulus(GO:0071373)
0.0 0.2 GO:0038098 sequestering of BMP from receptor via BMP binding(GO:0038098)
0.0 0.3 GO:0070537 histone H2A K63-linked deubiquitination(GO:0070537)
0.0 0.4 GO:0042866 pyruvate biosynthetic process(GO:0042866)
0.0 0.4 GO:2000660 negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
0.0 0.5 GO:0030916 otic vesicle formation(GO:0030916)
0.0 0.3 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.0 0.2 GO:0051066 dihydrobiopterin metabolic process(GO:0051066)
0.0 0.3 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.0 0.4 GO:1903764 regulation of potassium ion export across plasma membrane(GO:1903764)
0.0 0.2 GO:0001831 trophectodermal cellular morphogenesis(GO:0001831)
0.0 0.2 GO:1902255 positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator(GO:1902255)
0.0 0.5 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.0 0.6 GO:0050713 negative regulation of interleukin-1 beta secretion(GO:0050713)
0.0 0.1 GO:2000742 anterior head development(GO:0097065) regulation of anterior head development(GO:2000742) positive regulation of anterior head development(GO:2000744)
0.0 0.2 GO:0042360 vitamin E metabolic process(GO:0042360)
0.0 0.5 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.0 0.6 GO:1901725 regulation of cardiac muscle cell action potential involved in regulation of contraction(GO:0098909) regulation of histone deacetylase activity(GO:1901725) regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1902514)
0.0 0.2 GO:0001880 Mullerian duct regression(GO:0001880)
0.0 0.3 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
0.0 0.2 GO:1900245 positive regulation of MDA-5 signaling pathway(GO:1900245)
0.0 0.2 GO:0072752 cellular response to rapamycin(GO:0072752)
0.0 1.0 GO:0070987 error-free translesion synthesis(GO:0070987)
0.0 0.7 GO:0000712 resolution of meiotic recombination intermediates(GO:0000712)
0.0 0.6 GO:0015816 glycine transport(GO:0015816)
0.0 0.1 GO:1903598 positive regulation of gap junction assembly(GO:1903598)
0.0 0.3 GO:0032484 Ral protein signal transduction(GO:0032484) regulation of Ral protein signal transduction(GO:0032485)
0.0 0.3 GO:0002074 extraocular skeletal muscle development(GO:0002074)
0.0 0.3 GO:0002759 regulation of antimicrobial humoral response(GO:0002759)
0.0 0.4 GO:0003190 atrioventricular valve formation(GO:0003190)
0.0 0.3 GO:0070236 negative regulation of activation-induced cell death of T cells(GO:0070236)
0.0 0.3 GO:0017183 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.0 0.2 GO:1903826 arginine transmembrane transport(GO:1903826)
0.0 0.4 GO:0014067 negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067)
0.0 0.2 GO:0010265 SCF complex assembly(GO:0010265)
0.0 0.3 GO:0035973 aggrephagy(GO:0035973)
0.0 0.1 GO:0002933 lipid hydroxylation(GO:0002933)
0.0 0.4 GO:0016926 protein desumoylation(GO:0016926)
0.0 0.3 GO:1902412 regulation of mitotic cytokinesis(GO:1902412)
0.0 0.3 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.0 0.1 GO:0050882 voluntary musculoskeletal movement(GO:0050882)
0.0 0.8 GO:0036120 cellular response to platelet-derived growth factor stimulus(GO:0036120)
0.0 0.4 GO:0051256 mitotic spindle midzone assembly(GO:0051256)
0.0 0.5 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.0 0.3 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.0 0.3 GO:0000733 DNA strand renaturation(GO:0000733)
0.0 0.9 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 0.3 GO:0000012 single strand break repair(GO:0000012)
0.0 0.7 GO:0051764 actin crosslink formation(GO:0051764)
0.0 0.3 GO:0001542 ovulation from ovarian follicle(GO:0001542)
0.0 0.1 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
0.0 0.6 GO:0008608 attachment of spindle microtubules to kinetochore(GO:0008608)
0.0 0.2 GO:0021853 cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.0 0.0 GO:0035995 detection of muscle stretch(GO:0035995)
0.0 0.1 GO:1903377 negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
0.0 0.4 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.0 0.4 GO:1904776 regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.0 0.3 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.0 0.5 GO:0045948 positive regulation of translational initiation(GO:0045948)
0.0 0.1 GO:2001106 regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.0 0.1 GO:0003025 regulation of systemic arterial blood pressure by baroreceptor feedback(GO:0003025)
0.0 0.7 GO:0002092 positive regulation of receptor internalization(GO:0002092)
0.0 0.1 GO:0031987 locomotion involved in locomotory behavior(GO:0031987)
0.0 0.2 GO:0090160 Golgi to lysosome transport(GO:0090160)
0.0 0.4 GO:0045332 phospholipid translocation(GO:0045332)
0.0 0.0 GO:0072299 negative regulation of metanephric glomerulus development(GO:0072299) negative regulation of metanephric glomerular mesangial cell proliferation(GO:0072302)
0.0 0.1 GO:2000389 regulation of neutrophil extravasation(GO:2000389)
0.0 0.3 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.0 0.2 GO:1900181 negative regulation of protein localization to nucleus(GO:1900181)
0.0 0.1 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.0 1.3 GO:0032755 positive regulation of interleukin-6 production(GO:0032755)
0.0 0.4 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.5 GO:0006099 tricarboxylic acid cycle(GO:0006099)
0.0 0.3 GO:0003334 keratinocyte development(GO:0003334)
0.0 0.3 GO:0050832 defense response to fungus(GO:0050832)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.4 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.5 3.9 GO:0097452 GAIT complex(GO:0097452)
0.2 2.7 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.2 0.8 GO:1990423 RZZ complex(GO:1990423)
0.2 1.6 GO:0005663 DNA replication factor C complex(GO:0005663)
0.2 0.9 GO:0000799 nuclear condensin complex(GO:0000799)
0.1 0.4 GO:1990666 PCSK9-LDLR complex(GO:1990666)
0.1 0.4 GO:1990298 mitotic checkpoint complex(GO:0033597) bub1-bub3 complex(GO:1990298)
0.1 0.7 GO:0031673 H zone(GO:0031673)
0.1 0.4 GO:1902912 pyruvate kinase complex(GO:1902912)
0.1 1.7 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.1 0.4 GO:0048476 Holliday junction resolvase complex(GO:0048476)
0.1 0.8 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.1 0.6 GO:1990761 growth cone lamellipodium(GO:1990761)
0.1 0.5 GO:0000138 Golgi trans cisterna(GO:0000138)
0.0 0.1 GO:0002944 cyclin K-CDK12 complex(GO:0002944)
0.0 0.8 GO:0002199 zona pellucida receptor complex(GO:0002199)
0.0 0.4 GO:0044354 pinosome(GO:0044352) macropinosome(GO:0044354)
0.0 0.2 GO:0097362 MCM8-MCM9 complex(GO:0097362)
0.0 0.6 GO:0072559 NLRP3 inflammasome complex(GO:0072559)
0.0 0.4 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.0 3.1 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 0.4 GO:0060091 kinocilium(GO:0060091)
0.0 0.2 GO:0070369 Scrib-APC-beta-catenin complex(GO:0034750) beta-catenin-TCF7L2 complex(GO:0070369)
0.0 0.3 GO:0070531 BRCA1-A complex(GO:0070531)
0.0 0.3 GO:0005955 calcineurin complex(GO:0005955)
0.0 0.5 GO:0036038 MKS complex(GO:0036038)
0.0 0.4 GO:0097025 lateral loop(GO:0043219) MPP7-DLG1-LIN7 complex(GO:0097025)
0.0 0.1 GO:0002189 ribose phosphate diphosphokinase complex(GO:0002189)
0.0 0.4 GO:0008091 spectrin(GO:0008091)
0.0 0.1 GO:0030430 host cell cytoplasm(GO:0030430) host cell cytoplasm part(GO:0033655)
0.0 0.2 GO:0005827 polar microtubule(GO:0005827)
0.0 0.1 GO:0030906 retromer, cargo-selective complex(GO:0030906)
0.0 0.5 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.4 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.6 GO:0044295 axonal growth cone(GO:0044295)
0.0 0.1 GO:0034274 Atg12-Atg5-Atg16 complex(GO:0034274)
0.0 0.3 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 0.2 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.4 GO:0030014 CCR4-NOT complex(GO:0030014)
0.0 0.2 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 0.3 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 0.3 GO:0071564 npBAF complex(GO:0071564)
0.0 0.2 GO:0031931 TORC1 complex(GO:0031931)
0.0 0.1 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.0 0.1 GO:0000801 central element(GO:0000801)
0.0 0.2 GO:0030061 mitochondrial crista(GO:0030061)
0.0 0.3 GO:0032982 myosin filament(GO:0032982)
0.0 0.9 GO:0002102 podosome(GO:0002102)
0.0 0.4 GO:0016580 Sin3 complex(GO:0016580)
0.0 0.2 GO:0032039 integrator complex(GO:0032039)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 3.9 GO:0004827 glutamate-tRNA ligase activity(GO:0004818) proline-tRNA ligase activity(GO:0004827)
0.8 2.4 GO:0016418 S-acetyltransferase activity(GO:0016418)
0.7 2.7 GO:0098808 mRNA cap binding(GO:0098808)
0.2 0.7 GO:0003918 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.2 0.5 GO:0019781 NEDD8 activating enzyme activity(GO:0019781)
0.2 1.7 GO:0043515 kinetochore binding(GO:0043515)
0.2 0.5 GO:0061598 molybdopterin adenylyltransferase activity(GO:0061598) molybdopterin molybdotransferase activity(GO:0061599)
0.2 1.6 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.1 0.5 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.1 0.6 GO:0032089 NACHT domain binding(GO:0032089)
0.1 0.3 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.1 0.5 GO:0047493 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.1 0.4 GO:0004743 pyruvate kinase activity(GO:0004743)
0.1 0.2 GO:0000026 alpha-1,2-mannosyltransferase activity(GO:0000026)
0.1 0.4 GO:0010484 H3 histone acetyltransferase activity(GO:0010484)
0.1 0.6 GO:0009922 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.1 0.2 GO:0004155 6,7-dihydropteridine reductase activity(GO:0004155)
0.1 0.3 GO:0070259 tyrosyl-DNA phosphodiesterase activity(GO:0070259)
0.1 0.4 GO:0030229 very-low-density lipoprotein particle receptor activity(GO:0030229)
0.0 0.7 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.0 0.2 GO:0004031 aldehyde oxidase activity(GO:0004031)
0.0 0.3 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.0 0.8 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.0 0.5 GO:0051011 microtubule minus-end binding(GO:0051011)
0.0 0.3 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.0 0.2 GO:0003990 acetylcholinesterase activity(GO:0003990)
0.0 0.3 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.0 0.6 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.0 0.2 GO:0031208 POZ domain binding(GO:0031208)
0.0 0.1 GO:0008431 vitamin E binding(GO:0008431)
0.0 0.6 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.0 0.3 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.0 0.3 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.0 0.6 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.0 0.4 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.0 0.1 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0 0.4 GO:0042731 PH domain binding(GO:0042731)
0.0 0.4 GO:0097016 L27 domain binding(GO:0097016)
0.0 0.4 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.0 0.4 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.0 1.2 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.2 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
0.0 0.2 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.0 0.2 GO:0015181 arginine transmembrane transporter activity(GO:0015181)
0.0 0.7 GO:0000030 mannosyltransferase activity(GO:0000030)
0.0 0.3 GO:0036310 annealing helicase activity(GO:0036310)
0.0 0.2 GO:0060002 plus-end directed microfilament motor activity(GO:0060002)
0.0 0.1 GO:0019776 Atg8 ligase activity(GO:0019776)
0.0 0.5 GO:0010485 H4 histone acetyltransferase activity(GO:0010485)
0.0 0.2 GO:0016015 morphogen activity(GO:0016015)
0.0 0.6 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 0.1 GO:0003896 DNA primase activity(GO:0003896)
0.0 0.1 GO:0004619 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.0 0.2 GO:0051425 PTB domain binding(GO:0051425)
0.0 0.1 GO:0047631 ADP-ribose diphosphatase activity(GO:0047631)
0.0 0.7 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 1.0 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.1 GO:0001972 retinoic acid binding(GO:0001972)
0.0 0.4 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.6 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.1 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.0 0.0 GO:0070283 lipoate synthase activity(GO:0016992) radical SAM enzyme activity(GO:0070283)
0.0 0.1 GO:0008241 peptidyl-dipeptidase activity(GO:0008241)
0.0 0.1 GO:0005119 smoothened binding(GO:0005119)
0.0 0.2 GO:0070411 I-SMAD binding(GO:0070411)
0.0 0.3 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 0.2 GO:0051400 BH domain binding(GO:0051400)
0.0 0.2 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.0 0.1 GO:0052740 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
0.0 0.1 GO:0030346 protein phosphatase 2B binding(GO:0030346)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.8 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.0 1.4 PID AURORA B PATHWAY Aurora B signaling
0.0 1.0 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 0.4 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0 0.4 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 0.7 PID REELIN PATHWAY Reelin signaling pathway
0.0 0.9 PID ATR PATHWAY ATR signaling pathway
0.0 0.5 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.0 0.3 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.7 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.1 3.9 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.1 0.4 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0 0.6 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 0.7 REACTOME POL SWITCHING Genes involved in Polymerase switching
0.0 0.8 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.0 1.1 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.0 0.9 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 0.7 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 0.6 REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.0 1.5 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 0.4 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.5 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.2 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.0 0.8 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.3 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.6 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.0 0.4 REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS Genes involved in Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components
0.0 0.2 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 0.3 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)