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SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for HOXC13

Z-value: 0.69

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Transcription factors associated with HOXC13

Gene Symbol Gene ID Gene Info
ENSG00000123364.3 homeobox C13

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HOXC13hg19_v2_chr12_+_54332535_54332636-0.741.8e-04Click!

Activity profile of HOXC13 motif

Sorted Z-values of HOXC13 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr1_+_153003671 3.47 ENST00000307098.4
small proline-rich protein 1B
chr18_+_61554932 3.17 ENST00000299502.4
ENST00000457692.1
ENST00000413956.1
serpin peptidase inhibitor, clade B (ovalbumin), member 2
chr3_-_172241250 3.03 ENST00000420541.2
ENST00000241261.2
tumor necrosis factor (ligand) superfamily, member 10
chr1_-_209975494 2.35 ENST00000456314.1
interferon regulatory factor 6
chr17_-_74639886 1.76 ENST00000156626.7
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1
chr7_-_41742697 1.46 ENST00000242208.4
inhibin, beta A
chr6_+_106988986 1.44 ENST00000457437.1
ENST00000535438.1
absent in melanoma 1
chr6_-_32784687 1.35 ENST00000447394.1
ENST00000438763.2
major histocompatibility complex, class II, DO beta
chr10_+_51549498 1.34 ENST00000358559.2
ENST00000298239.6
microseminoprotein, beta-
chr6_-_150217195 1.20 ENST00000532335.1
retinoic acid early transcript 1E
chr2_+_210444142 1.12 ENST00000360351.4
ENST00000361559.4
microtubule-associated protein 2
chr1_+_158979686 1.08 ENST00000368132.3
ENST00000295809.7
interferon, gamma-inducible protein 16
chr15_+_94774767 1.07 ENST00000543482.1
multiple C2 domains, transmembrane 2
chr1_+_158979680 1.07 ENST00000368131.4
ENST00000340979.6
interferon, gamma-inducible protein 16
chr5_-_39270725 1.03 ENST00000512138.1
ENST00000512982.1
ENST00000540520.1
FYN binding protein
chr21_+_39628655 1.03 ENST00000398925.1
ENST00000398928.1
ENST00000328656.4
ENST00000443341.1
potassium inwardly-rectifying channel, subfamily J, member 15
chr1_+_17516275 1.00 ENST00000412427.1
RP11-380J14.1
chr10_+_118187379 0.99 ENST00000369230.3
pancreatic lipase-related protein 3
chr2_+_210443993 0.98 ENST00000392193.1
microtubule-associated protein 2
chr1_-_55266926 0.89 ENST00000371276.4
tetratricopeptide repeat domain 22
chr7_-_27169801 0.88 ENST00000511914.1
homeobox A4
chrX_-_30993201 0.85 ENST00000288422.2
ENST00000378932.2
TGF-beta activated kinase 1/MAP3K7 binding protein 3
chr1_+_174844645 0.85 ENST00000486220.1
RAB GTPase activating protein 1-like
chr19_-_20748614 0.84 ENST00000596797.1
zinc finger protein 737
chr12_-_57630873 0.81 ENST00000556732.1
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2
chr15_-_44069741 0.81 ENST00000319359.3
elongation factor RNA polymerase II-like 3
chr16_-_9770700 0.79 ENST00000561538.1
Uncharacterized protein
chr4_-_83769996 0.78 ENST00000511338.1
SEC31 homolog A (S. cerevisiae)
chr3_-_195310802 0.76 ENST00000421243.1
ENST00000453131.1
apolipoprotein D
chr19_+_50084561 0.75 ENST00000246794.5
proline rich Gla (G-carboxyglutamic acid) 2
chr12_-_52828147 0.75 ENST00000252245.5
keratin 75
chr4_-_148605265 0.73 ENST00000541232.1
ENST00000322396.6
protein arginine methyltransferase 10 (putative)
chr19_+_45409011 0.73 ENST00000252486.4
ENST00000446996.1
ENST00000434152.1
apolipoprotein E
chrM_+_8527 0.72 ENST00000361899.2
mitochondrially encoded ATP synthase 6
chr3_+_50211240 0.71 ENST00000420831.1
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
chr2_+_102953608 0.70 ENST00000311734.2
ENST00000409584.1
interleukin 1 receptor-like 1
chr14_+_72052983 0.70 ENST00000358550.2
signal-induced proliferation-associated 1 like 1
chr2_+_210444298 0.67 ENST00000445941.1
microtubule-associated protein 2
chr4_+_119200215 0.67 ENST00000602573.1
small nucleolar RNA host gene 8 (non-protein coding)
chr12_-_53207842 0.66 ENST00000458244.2
keratin 4
chr19_+_21106081 0.65 ENST00000300540.3
ENST00000595854.1
ENST00000601284.1
ENST00000328178.8
ENST00000599885.1
ENST00000596476.1
ENST00000345030.6
zinc finger protein 85
chr6_-_112080256 0.63 ENST00000462856.2
ENST00000229471.4
FYN oncogene related to SRC, FGR, YES
chr14_-_50319482 0.62 ENST00000546046.1
ENST00000555970.1
ENST00000554626.1
ENST00000545773.1
ENST00000556672.1
nuclear export mediator factor
chr4_+_128702969 0.59 ENST00000508776.1
ENST00000439123.2
heat shock 70kDa protein 4-like
chr17_-_8286484 0.58 ENST00000582556.1
ENST00000584164.1
ENST00000293842.5
ENST00000584343.1
ENST00000578812.1
ENST00000583011.1
ribosomal protein L26
chr1_+_174128639 0.57 ENST00000251507.4
RAB GTPase activating protein 1-like
chr4_+_54243917 0.55 ENST00000507166.1
factor interacting with PAPOLA and CPSF1
chrM_+_8366 0.55 ENST00000361851.1
mitochondrially encoded ATP synthase 8
chr17_-_74639730 0.54 ENST00000589992.1
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1
chr10_+_24738355 0.54 ENST00000307544.6
KIAA1217
chr3_-_179169181 0.54 ENST00000497513.1
guanine nucleotide binding protein (G protein), beta polypeptide 4
chr14_-_88200641 0.53 ENST00000556168.1
RP11-1152H15.1
chr9_+_112887772 0.53 ENST00000259318.7
A kinase (PRKA) anchor protein 2
chr5_+_110409012 0.51 ENST00000379706.4
thymic stromal lymphopoietin
chr17_-_39553844 0.50 ENST00000251645.2
keratin 31
chr14_-_50319758 0.50 ENST00000298310.5
nuclear export mediator factor
chr20_-_52687059 0.50 ENST00000371435.2
ENST00000395961.3
breast carcinoma amplified sequence 1
chr15_-_99057551 0.49 ENST00000558256.1
family with sequence similarity 169, member B
chr3_-_99569821 0.47 ENST00000487087.1
filamin A interacting protein 1-like
chr1_+_152730499 0.47 ENST00000368773.1
keratinocyte proline-rich protein
chr1_+_17559776 0.46 ENST00000537499.1
ENST00000413717.2
ENST00000536552.1
peptidyl arginine deiminase, type I
chr20_-_44420507 0.46 ENST00000243938.4
WAP four-disulfide core domain 3
chr2_+_138721850 0.45 ENST00000329366.4
ENST00000280097.3
histamine N-methyltransferase
chr4_-_170533723 0.45 ENST00000510533.1
ENST00000439128.2
ENST00000511633.1
ENST00000512193.1
ENST00000507142.1
NIMA-related kinase 1
chr19_-_38085633 0.44 ENST00000593133.1
ENST00000590751.1
ENST00000358744.3
ENST00000328550.2
ENST00000451802.2
zinc finger protein 571
chr5_-_79287060 0.43 ENST00000512560.1
ENST00000509852.1
ENST00000512528.1
metaxin 3
chr2_+_162016804 0.42 ENST00000392749.2
ENST00000440506.1
TRAF family member-associated NFKB activator
chr11_+_85566422 0.42 ENST00000342404.3
coiled-coil domain containing 83
chr17_+_66521936 0.41 ENST00000592800.1
protein kinase, cAMP-dependent, regulatory, type I, alpha
chr2_+_162016827 0.39 ENST00000429217.1
ENST00000406287.1
ENST00000402568.1
TRAF family member-associated NFKB activator
chr3_-_126373929 0.39 ENST00000523403.1
ENST00000524230.2
thioredoxin reductase 3
chr3_+_42977846 0.39 ENST00000383748.4
KRAB box domain containing 1
chr13_+_103451399 0.38 ENST00000257336.1
ENST00000448849.2
basic, immunoglobulin-like variable motif containing
chr6_-_36515177 0.37 ENST00000229812.7
serine/threonine kinase 38
chr3_+_57875738 0.37 ENST00000417128.1
ENST00000438794.1
sarcolemma associated protein
chr21_-_27423339 0.36 ENST00000415997.1
amyloid beta (A4) precursor protein
chr1_+_90460661 0.36 ENST00000340281.4
ENST00000361911.5
ENST00000370447.3
ENST00000455342.2
zinc finger protein 326
chr3_+_100428188 0.35 ENST00000418917.2
ENST00000490574.1
TRK-fused gene
chr3_+_122513642 0.35 ENST00000261038.5
disrupted in renal carcinoma 2
chr10_+_13628933 0.35 ENST00000417658.1
ENST00000320054.4
pre-mRNA processing factor 18
chr2_+_192109911 0.34 ENST00000418908.1
ENST00000339514.4
ENST00000392318.3
myosin IB
chr15_+_79166065 0.33 ENST00000559690.1
ENST00000559158.1
mortality factor 4 like 1
chrX_+_13707235 0.33 ENST00000464506.1
RAB9A, member RAS oncogene family
chr1_+_174128704 0.32 ENST00000457696.1
RAB GTPase activating protein 1-like
chr2_+_162016916 0.32 ENST00000405852.1
TRAF family member-associated NFKB activator
chr12_+_45609862 0.32 ENST00000423947.3
ENST00000435642.1
anoctamin 6
chr6_-_11807277 0.31 ENST00000379415.2
androgen-dependent TFPI-regulating protein
chr12_+_45609797 0.31 ENST00000425752.2
anoctamin 6
chr18_-_46895066 0.31 ENST00000583225.1
ENST00000584983.1
ENST00000583280.1
ENST00000581738.1
dymeclin
chr4_+_106631966 0.31 ENST00000360505.5
ENST00000510865.1
ENST00000509336.1
glutathione S-transferase, C-terminal domain containing
chr19_+_21265028 0.30 ENST00000291770.7
zinc finger protein 714
chr3_-_46037299 0.30 ENST00000296137.2
FYVE and coiled-coil domain containing 1
chr7_+_134551583 0.30 ENST00000435928.1
caldesmon 1
chr3_+_111630451 0.30 ENST00000495180.1
pleckstrin homology-like domain, family B, member 2
chr19_+_16999654 0.30 ENST00000248076.3
coagulation factor II (thrombin) receptor-like 3
chr1_+_174128536 0.30 ENST00000357444.6
ENST00000367689.3
RAB GTPase activating protein 1-like
chr1_-_86174065 0.30 ENST00000370574.3
ENST00000431532.2
zinc finger, HIT-type containing 6
chr7_+_138915102 0.30 ENST00000486663.1
ubinuclein 2
chr7_-_92777606 0.30 ENST00000437805.1
ENST00000446959.1
ENST00000439952.1
ENST00000414791.1
ENST00000446033.1
ENST00000411955.1
ENST00000318238.4
sterile alpha motif domain containing 9-like
chr19_-_56904799 0.29 ENST00000589895.1
ENST00000589143.1
ENST00000301310.4
ENST00000586929.1
zinc finger protein 582
chr1_-_220220000 0.29 ENST00000366923.3
glutamyl-prolyl-tRNA synthetase
chr12_-_91546926 0.29 ENST00000550758.1
decorin
chr3_-_71179699 0.29 ENST00000497355.1
forkhead box P1
chr19_-_18632861 0.29 ENST00000262809.4
elongation factor RNA polymerase II
chr3_+_99986036 0.28 ENST00000471098.1
TBC1 domain family, member 23
chr7_-_64023441 0.28 ENST00000309683.6
zinc finger protein 680
chr11_-_85565906 0.28 ENST00000544076.1
CDNA FLJ26432 fis, clone KDN01418; Uncharacterized protein
chr20_+_19870167 0.28 ENST00000440354.2
Ras and Rab interactor 2
chr18_-_5544241 0.28 ENST00000341928.2
ENST00000540638.2
erythrocyte membrane protein band 4.1-like 3
chr6_-_75953484 0.28 ENST00000472311.2
ENST00000460985.1
ENST00000377978.3
ENST00000509698.1
ENST00000230459.4
ENST00000370089.2
cytochrome c oxidase subunit VIIa polypeptide 2 (liver)
chr1_+_213224572 0.27 ENST00000543470.1
ENST00000366960.3
ENST00000366959.3
ENST00000543354.1
ribosomal protein S6 kinase, 52kDa, polypeptide 1
chr21_+_25801041 0.27 ENST00000453784.2
ENST00000423581.1
AP000476.1
chr19_-_6737576 0.27 ENST00000601716.1
ENST00000264080.7
G protein-coupled receptor 108
chr19_-_6279932 0.26 ENST00000252674.7
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 1
chr14_+_23727694 0.26 ENST00000399905.1
ENST00000470456.1
chromosome 14 open reading frame 164
chr4_+_119199904 0.25 ENST00000602483.1
ENST00000602819.1
small nucleolar RNA host gene 8 (non-protein coding)
chr11_+_101983176 0.25 ENST00000524575.1
Yes-associated protein 1
chr3_-_112320749 0.25 ENST00000610103.1
RP11-572C15.6
chr5_+_36608280 0.25 ENST00000513646.1
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr8_-_82608409 0.25 ENST00000518568.1
solute carrier family 10, member 5
chr17_-_56769382 0.25 ENST00000240361.8
ENST00000349033.5
ENST00000389934.3
testis expressed 14
chr19_-_23869999 0.25 ENST00000601935.1
ENST00000359788.4
ENST00000600313.1
ENST00000596211.1
ENST00000599168.1
zinc finger protein 675
chr7_-_30066233 0.24 ENST00000222803.5
FK506 binding protein 14, 22 kDa
chr7_-_104909435 0.24 ENST00000357311.3
SRSF protein kinase 2
chr18_-_24722995 0.23 ENST00000581714.1
carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 9
chrX_-_135338503 0.23 ENST00000370663.5
MAP7 domain containing 3
chr2_-_122262593 0.22 ENST00000418989.1
cytoplasmic linker associated protein 1
chr12_-_49418407 0.22 ENST00000526209.1
lysine (K)-specific methyltransferase 2D
chr5_-_176433565 0.22 ENST00000428382.2
ubiquitin interaction motif containing 1
chr6_-_112081113 0.22 ENST00000517419.1
FYN oncogene related to SRC, FGR, YES
chr11_+_63606373 0.21 ENST00000402010.2
ENST00000315032.8
ENST00000377809.4
ENST00000413835.2
ENST00000377810.3
MAP/microtubule affinity-regulating kinase 2
chr3_-_51533966 0.21 ENST00000504652.1
Vpr (HIV-1) binding protein
chr13_-_51101468 0.21 ENST00000428276.1
RP11-175B12.2
chr22_+_32439019 0.21 ENST00000266088.4
solute carrier family 5 (sodium/glucose cotransporter), member 1
chr14_+_73634537 0.21 ENST00000406768.1
presenilin 1
chr14_-_92333873 0.21 ENST00000435962.2
tandem C2 domains, nuclear
chr7_+_57509877 0.20 ENST00000420713.1
zinc finger protein 716
chr1_+_40862501 0.20 ENST00000539317.1
small ArfGAP2
chr5_+_42756903 0.20 ENST00000361970.5
ENST00000388827.4
coiled-coil domain containing 152
chr1_-_33502441 0.20 ENST00000548033.1
ENST00000487289.1
ENST00000373449.2
ENST00000480134.1
ENST00000467905.1
adenylate kinase 2
chr6_+_151042224 0.20 ENST00000358517.2
pleckstrin homology domain containing, family G (with RhoGef domain) member 1
chr1_+_206858232 0.20 ENST00000294981.4
mitogen-activated protein kinase-activated protein kinase 2
chr12_-_4647606 0.19 ENST00000261250.3
ENST00000541014.1
ENST00000545746.1
ENST00000542080.1
chromosome 12 open reading frame 4
chr2_+_33359687 0.19 ENST00000402934.1
ENST00000404525.1
ENST00000407925.1
latent transforming growth factor beta binding protein 1
chr10_+_90484301 0.19 ENST00000404190.1
lipase, family member K
chr17_-_28257080 0.19 ENST00000579954.1
ENST00000540801.1
ENST00000269033.3
ENST00000590153.1
ENST00000582084.1
slingshot protein phosphatase 2
chr5_+_150020214 0.19 ENST00000307662.4
synaptopodin
chr12_+_111537227 0.19 ENST00000397643.3
cut-like homeobox 2
chr17_-_39140549 0.18 ENST00000377755.4
keratin 40
chr6_-_33239712 0.18 ENST00000436044.2
vacuolar protein sorting 52 homolog (S. cerevisiae)
chr3_+_57875711 0.18 ENST00000442599.2
sarcolemma associated protein
chr12_+_93115281 0.18 ENST00000549856.1
pleckstrin homology domain containing, family G (with RhoGef domain) member 7
chr15_+_92006567 0.18 ENST00000554333.1
RP11-661P17.1
chr7_+_90012986 0.18 ENST00000416322.1
claudin 12
chr2_+_48010312 0.17 ENST00000540021.1
mutS homolog 6
chr2_+_33359646 0.17 ENST00000390003.4
ENST00000418533.2
latent transforming growth factor beta binding protein 1
chr17_+_29664830 0.17 ENST00000444181.2
ENST00000417592.2
neurofibromin 1
chr1_+_78511586 0.17 ENST00000370759.3
GIPC PDZ domain containing family, member 2
chr16_-_46865286 0.17 ENST00000285697.4
chromosome 16 open reading frame 87
chr16_+_81348528 0.17 ENST00000568107.2
gigaxonin
chr11_-_124670550 0.16 ENST00000239614.4
Myb/SANT-like DNA-binding domain containing 2
chr1_+_100435986 0.16 ENST00000532693.1
solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3
chr2_-_207078086 0.16 ENST00000442134.1
G protein-coupled receptor 1
chr4_+_119199864 0.16 ENST00000602414.1
ENST00000602520.1
small nucleolar RNA host gene 8 (non-protein coding)
chr12_+_45609893 0.16 ENST00000320560.8
anoctamin 6
chr14_-_68000442 0.15 ENST00000554278.1
transmembrane protein 229B
chr3_+_185080908 0.15 ENST00000265026.3
mitogen-activated protein kinase kinase kinase 13
chr12_-_89413456 0.15 ENST00000500381.2
RP11-13A1.1
chr10_-_70287231 0.15 ENST00000609923.1
solute carrier family 25 (mitochondrial carrier; Graves disease autoantigen), member 16
chr2_-_207078154 0.15 ENST00000447845.1
G protein-coupled receptor 1
chr19_+_39574945 0.15 ENST00000331256.5
Iron/zinc purple acid phosphatase-like protein
chr2_+_61372226 0.15 ENST00000426997.1
chromosome 2 open reading frame 74
chr19_+_21264980 0.15 ENST00000596053.1
ENST00000597086.1
ENST00000596143.1
ENST00000596367.1
ENST00000601416.1
zinc finger protein 714
chr2_+_138722028 0.15 ENST00000280096.5
histamine N-methyltransferase
chr12_+_70219052 0.14 ENST00000552032.2
ENST00000547771.2
myelin regulatory factor-like
chr19_+_7011509 0.14 ENST00000377296.3
Uncharacterized protein
chr6_-_33239612 0.14 ENST00000482399.1
ENST00000445902.2
vacuolar protein sorting 52 homolog (S. cerevisiae)
chr19_+_52102540 0.14 ENST00000601315.1
AC018755.17
chr3_+_100428316 0.14 ENST00000479672.1
ENST00000476228.1
ENST00000463568.1
TRK-fused gene
chr19_+_41698927 0.14 ENST00000310054.4
cytochrome P450, family 2, subfamily S, polypeptide 1
chr7_-_86595190 0.13 ENST00000398276.2
ENST00000416314.1
ENST00000425689.1
KIAA1324-like
chr18_-_74839891 0.13 ENST00000581878.1
myelin basic protein
chr3_-_98241760 0.13 ENST00000507874.1
ENST00000502299.1
ENST00000508659.1
ENST00000510545.1
ENST00000511667.1
ENST00000394185.2
ENST00000394181.2
ENST00000508902.1
ENST00000341181.6
ENST00000437922.1
ENST00000394180.2
claudin domain containing 1
chr15_+_74421961 0.13 ENST00000565159.1
ENST00000567206.1
immunoglobulin superfamily containing leucine-rich repeat 2
chr4_+_170581213 0.13 ENST00000507875.1
chloride channel, voltage-sensitive 3
chr8_+_95565947 0.13 ENST00000523011.1
RP11-267M23.4
chr1_-_154150651 0.12 ENST00000302206.5
tropomyosin 3
chr12_+_93096759 0.12 ENST00000544406.2
chromosome 12 open reading frame 74
chr13_+_28813645 0.11 ENST00000282391.5
PAN3 poly(A) specific ribonuclease subunit homolog (S. cerevisiae)
chr11_+_101785727 0.11 ENST00000263468.8
KIAA1377
chr1_+_46769303 0.11 ENST00000311672.5
ubiquinol-cytochrome c reductase hinge protein
chr1_-_155880672 0.11 ENST00000609492.1
ENST00000368322.3
Ras-like without CAAX 1
chr14_-_82089405 0.11 ENST00000554211.1
RP11-799P8.1
chr1_-_47407111 0.11 ENST00000371904.4
cytochrome P450, family 4, subfamily A, polypeptide 11
chr15_-_78538025 0.11 ENST00000560817.1
acyl-CoA synthetase bubblegum family member 1
chr7_+_23719749 0.11 ENST00000409192.3
ENST00000344962.4
ENST00000409653.1
ENST00000409994.3
family with sequence similarity 221, member A
chr5_-_74532696 0.10 ENST00000506364.2
ENST00000274361.3
ankyrin repeat domain 31
chr14_-_24701539 0.10 ENST00000534348.1
ENST00000524927.1
ENST00000250495.5
NEDD8-MDP1 readthrough
neural precursor cell expressed, developmentally down-regulated 8
chr11_+_94706804 0.10 ENST00000335080.5
lysine (K)-specific demethylase 4D
chr19_+_21264943 0.10 ENST00000597424.1
zinc finger protein 714

Network of associatons between targets according to the STRING database.

First level regulatory network of HOXC13

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.5 GO:0060278 regulation of ovulation(GO:0060278) positive regulation of ovulation(GO:0060279)
0.4 1.3 GO:0002581 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581)
0.2 0.7 GO:2000646 lipid transport involved in lipid storage(GO:0010877) positive regulation of receptor catabolic process(GO:2000646)
0.2 0.8 GO:0097045 phosphatidylserine exposure on blood platelet(GO:0097045)
0.2 0.8 GO:2000097 regulation of smooth muscle cell-matrix adhesion(GO:2000097)
0.1 0.3 GO:0071048 nuclear mRNA surveillance of spliceosomal pre-mRNA splicing(GO:0071030) nuclear retention of unspliced pre-mRNA at the site of transcription(GO:0071048)
0.1 3.0 GO:0097296 activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097296)
0.1 0.9 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.1 2.3 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.1 0.3 GO:0007439 ectodermal digestive tract development(GO:0007439) embryonic ectodermal digestive tract development(GO:0048611)
0.1 0.7 GO:0038172 interleukin-33-mediated signaling pathway(GO:0038172)
0.1 0.6 GO:0001692 histamine metabolic process(GO:0001692)
0.1 0.3 GO:0006433 glutamyl-tRNA aminoacylation(GO:0006424) prolyl-tRNA aminoacylation(GO:0006433)
0.1 0.6 GO:0051563 smooth endoplasmic reticulum calcium ion homeostasis(GO:0051563)
0.1 0.5 GO:0036414 protein citrullination(GO:0018101) histone citrullination(GO:0036414)
0.1 0.6 GO:1902231 regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902162) positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902164) positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.1 0.3 GO:0042796 snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.1 0.5 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.1 0.3 GO:0044362 modulation of molecular function in other organism(GO:0044359) negative regulation of molecular function in other organism(GO:0044362) negative regulation of molecular function in other organism involved in symbiotic interaction(GO:0052204) modulation of molecular function in other organism involved in symbiotic interaction(GO:0052205) negative regulation by host of symbiont molecular function(GO:0052405) modification by host of symbiont molecular function(GO:0052428)
0.1 2.4 GO:0060644 mammary gland epithelial cell differentiation(GO:0060644)
0.1 0.8 GO:1902951 negative regulation of dendritic spine maintenance(GO:1902951)
0.1 0.2 GO:0061534 gamma-aminobutyric acid secretion, neurotransmission(GO:0061534)
0.1 0.7 GO:0035290 trunk segmentation(GO:0035290) trunk neural crest cell migration(GO:0036484) ventral trunk neural crest cell migration(GO:0036486) neural crest cell migration involved in autonomic nervous system development(GO:1901166)
0.0 0.3 GO:0032625 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.0 3.8 GO:0018149 peptide cross-linking(GO:0018149)
0.0 1.9 GO:0042730 fibrinolysis(GO:0042730)
0.0 0.2 GO:0003095 pressure natriuresis(GO:0003095)
0.0 0.2 GO:0006172 ADP biosynthetic process(GO:0006172)
0.0 0.2 GO:0035063 nuclear speck organization(GO:0035063)
0.0 0.2 GO:0001555 oocyte growth(GO:0001555)
0.0 1.3 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.0 0.4 GO:0035583 sequestering of TGFbeta in extracellular matrix(GO:0035583)
0.0 0.8 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 0.2 GO:0015788 UDP-N-acetylglucosamine transport(GO:0015788) UDP-N-acetylglucosamine transmembrane transport(GO:1990569)
0.0 0.6 GO:0098789 pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.0 0.2 GO:0098886 modification of dendritic spine(GO:0098886)
0.0 0.8 GO:1902166 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:1902166)
0.0 0.5 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.0 0.3 GO:0002175 protein localization to paranode region of axon(GO:0002175)
0.0 0.3 GO:0000492 box C/D snoRNP assembly(GO:0000492)
0.0 2.1 GO:0045824 negative regulation of innate immune response(GO:0045824)
0.0 0.3 GO:1901098 positive regulation of autophagosome maturation(GO:1901098)
0.0 0.2 GO:2000660 negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
0.0 0.2 GO:0070537 histone H2A K63-linked deubiquitination(GO:0070537)
0.0 0.1 GO:0061394 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394)
0.0 0.4 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.0 0.1 GO:0048388 endosomal lumen acidification(GO:0048388)
0.0 0.2 GO:0001951 intestinal D-glucose absorption(GO:0001951)
0.0 0.3 GO:0070779 gamma-aminobutyric acid biosynthetic process(GO:0009449) D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.0 0.2 GO:0032466 negative regulation of cytokinesis(GO:0032466)
0.0 0.1 GO:1904207 regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904207) positive regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904209)
0.0 0.3 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.0 2.7 GO:0001578 microtubule bundle formation(GO:0001578)
0.0 1.0 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 0.2 GO:0000710 meiotic mismatch repair(GO:0000710)
0.0 0.3 GO:0060155 platelet dense granule organization(GO:0060155)
0.0 1.0 GO:0001913 T cell mediated cytotoxicity(GO:0001913)
0.0 0.3 GO:0060449 bud elongation involved in lung branching(GO:0060449) positive regulation of stem cell population maintenance(GO:1902459)
0.0 2.0 GO:0031338 regulation of vesicle fusion(GO:0031338)
0.0 1.0 GO:0010107 potassium ion import(GO:0010107)
0.0 2.3 GO:0070268 cornification(GO:0070268)
0.0 0.1 GO:0002074 extraocular skeletal muscle development(GO:0002074)
0.0 0.1 GO:1900113 negative regulation of histone H3-K9 trimethylation(GO:1900113) positive regulation of double-strand break repair via nonhomologous end joining(GO:2001034)
0.0 0.2 GO:0044351 macropinocytosis(GO:0044351)
0.0 0.9 GO:0061001 regulation of dendritic spine morphogenesis(GO:0061001)
0.0 0.1 GO:0009257 10-formyltetrahydrofolate biosynthetic process(GO:0009257)
0.0 0.9 GO:0070423 nucleotide-binding oligomerization domain containing signaling pathway(GO:0070423)
0.0 0.3 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.1 GO:0043152 induction of bacterial agglutination(GO:0043152)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.5 GO:0043512 inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.3 2.8 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.2 0.7 GO:0034365 discoidal high-density lipoprotein particle(GO:0034365)
0.1 0.4 GO:0044609 DBIRD complex(GO:0044609)
0.1 0.3 GO:0071020 post-spliceosomal complex(GO:0071020)
0.1 0.3 GO:1990745 EARP complex(GO:1990745)
0.1 1.4 GO:0042613 MHC class II protein complex(GO:0042613)
0.1 0.2 GO:0097444 spine apparatus(GO:0097444)
0.1 1.3 GO:0045263 proton-transporting ATP synthase complex, coupling factor F(o)(GO:0045263)
0.1 0.2 GO:0031592 centrosomal corona(GO:0031592)
0.1 0.3 GO:0071149 TEAD-2-YAP complex(GO:0071149)
0.0 0.8 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.0 3.5 GO:0001533 cornified envelope(GO:0001533)
0.0 1.4 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.0 0.3 GO:1902560 GMP reductase complex(GO:1902560)
0.0 0.3 GO:0097452 GAIT complex(GO:0097452)
0.0 0.4 GO:1990812 growth cone filopodium(GO:1990812)
0.0 0.2 GO:0032301 MutSalpha complex(GO:0032301)
0.0 0.1 GO:0031251 PAN complex(GO:0031251)
0.0 0.3 GO:0070761 pre-snoRNP complex(GO:0070761)
0.0 0.6 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 0.3 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.0 0.3 GO:0030478 actin cap(GO:0030478)
0.0 0.3 GO:0045180 basal cortex(GO:0045180)
0.0 1.5 GO:0045095 keratin filament(GO:0045095)
0.0 1.4 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 0.2 GO:0035253 ciliary rootlet(GO:0035253) gamma-secretase complex(GO:0070765)
0.0 0.2 GO:0070531 BRCA1-A complex(GO:0070531)
0.0 0.4 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.4 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.0 0.3 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.0 0.2 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 0.1 GO:1990037 Lewy body core(GO:1990037)
0.0 0.1 GO:0033269 internode region of axon(GO:0033269)
0.0 0.5 GO:0000242 pericentriolar material(GO:0000242)
0.0 0.2 GO:0097427 microtubule bundle(GO:0097427)
0.0 0.1 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0 0.3 GO:0033270 paranode region of axon(GO:0033270)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.5 GO:0070699 type II activin receptor binding(GO:0070699)
0.2 0.7 GO:0002113 interleukin-33 binding(GO:0002113)
0.2 2.3 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.2 0.7 GO:0070326 very-low-density lipoprotein particle receptor binding(GO:0070326)
0.1 0.9 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.1 0.3 GO:0004827 glutamate-tRNA ligase activity(GO:0004818) proline-tRNA ligase activity(GO:0004827)
0.1 0.8 GO:0042610 CD8 receptor binding(GO:0042610)
0.1 1.2 GO:0046703 natural killer cell lectin-like receptor binding(GO:0046703)
0.1 0.5 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.1 1.4 GO:0032395 MHC class II receptor activity(GO:0032395)
0.1 2.7 GO:0002162 dystroglycan binding(GO:0002162)
0.1 0.3 GO:0000386 second spliceosomal transesterification activity(GO:0000386)
0.1 0.4 GO:0050436 microfibril binding(GO:0050436)
0.1 3.0 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 1.0 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 0.2 GO:0018685 alkane 1-monooxygenase activity(GO:0018685)
0.0 0.3 GO:0015057 thrombin receptor activity(GO:0015057)
0.0 0.3 GO:0003920 GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657)
0.0 1.2 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 0.8 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 0.2 GO:0032143 single thymine insertion binding(GO:0032143)
0.0 0.2 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.0 1.1 GO:0015002 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.2 GO:0005462 UDP-N-acetylglucosamine transmembrane transporter activity(GO:0005462)
0.0 0.2 GO:0047756 chondroitin 4-sulfotransferase activity(GO:0047756)
0.0 0.7 GO:0045499 chemorepellent activity(GO:0045499)
0.0 0.1 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.0 0.4 GO:0051425 PTB domain binding(GO:0051425)
0.0 0.3 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.0 3.4 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.2 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.0 0.1 GO:0016744 transferase activity, transferring aldehyde or ketonic groups(GO:0016744)
0.0 0.4 GO:0004791 thioredoxin-disulfide reductase activity(GO:0004791)
0.0 0.1 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.0 0.1 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
0.0 0.3 GO:0001094 TFIID-class transcription factor binding(GO:0001094)
0.0 0.4 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0 0.1 GO:0047006 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity(GO:0047006)
0.0 0.4 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0 0.3 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 0.3 GO:0042923 neuropeptide binding(GO:0042923)
0.0 0.1 GO:0016681 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0 0.7 GO:0071889 14-3-3 protein binding(GO:0071889)
0.0 0.4 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 0.1 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.0 0.6 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.0 0.1 GO:0004329 formate-tetrahydrofolate ligase activity(GO:0004329)
0.0 1.3 GO:0015078 hydrogen ion transmembrane transporter activity(GO:0015078)
0.0 1.3 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.1 GO:0015056 corticotrophin-releasing factor receptor activity(GO:0015056)
0.0 0.3 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.8 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 0.2 GO:0004017 adenylate kinase activity(GO:0004017)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 3.0 PID TRAIL PATHWAY TRAIL signaling pathway
0.0 1.5 PID ALK1 PATHWAY ALK1 signaling events
0.0 0.5 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 1.1 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 3.0 PID LKB1 PATHWAY LKB1 signaling events
0.0 1.0 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 0.3 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.5 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.1 3.0 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.1 0.9 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.1 0.5 REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA Genes involved in G beta:gamma signalling through PLC beta
0.0 0.8 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.0 0.7 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 0.8 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 2.0 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.8 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.0 1.0 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 0.5 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 1.0 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 0.5 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 0.2 REACTOME REGULATED PROTEOLYSIS OF P75NTR Genes involved in Regulated proteolysis of p75NTR
0.0 0.3 REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.0 1.0 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell