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SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for HOXC9

Z-value: 1.33

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Transcription factors associated with HOXC9

Gene Symbol Gene ID Gene Info
HOXC9
ENSG00000180806.4 homeobox C9

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HOXC9hg19_v2_chr12_+_54393880_543939620.502.5e-02Click!

Activity profile of HOXC9 motif

Sorted Z-values of HOXC9 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr3_+_149191723 4.12 ENST00000305354.4
TM4SF4
transmembrane 4 L six family member 4
chr5_+_175288631 3.55 ENST00000509837.1
CPLX2
complexin 2
chr17_+_67498538 2.91 ENST00000589647.1
MAP2K6
mitogen-activated protein kinase kinase 6
chr1_-_197115818 2.75 ENST00000367409.4
ENST00000294732.7
ASPM
asp (abnormal spindle) homolog, microcephaly associated (Drosophila)
chr2_-_225811747 2.65 ENST00000409592.3
DOCK10
dedicator of cytokinesis 10
chr12_+_20963647 2.51 ENST00000381545.3
SLCO1B3
solute carrier organic anion transporter family, member 1B3
chr2_+_196440692 2.50 ENST00000458054.1
SLC39A10
solute carrier family 39 (zinc transporter), member 10
chr5_+_169011033 2.27 ENST00000513795.1
SPDL1
spindle apparatus coiled-coil protein 1
chr3_-_124653579 2.22 ENST00000478191.1
ENST00000311075.3
MUC13
mucin 13, cell surface associated
chr17_+_67498295 2.19 ENST00000589295.1
MAP2K6
mitogen-activated protein kinase kinase 6
chr17_-_46690839 2.18 ENST00000498634.2
HOXB8
homeobox B8
chr8_-_81083890 2.17 ENST00000518937.1
TPD52
tumor protein D52
chr16_-_66907139 2.17 ENST00000561579.2
NAE1
NEDD8 activating enzyme E1 subunit 1
chr3_+_87276407 1.98 ENST00000471660.1
ENST00000263780.4
ENST00000494980.1
CHMP2B
charged multivesicular body protein 2B
chr18_+_32558380 1.96 ENST00000588349.2
MAPRE2
microtubule-associated protein, RP/EB family, member 2
chr5_-_58295712 1.95 ENST00000317118.8
PDE4D
phosphodiesterase 4D, cAMP-specific
chr2_+_37571717 1.87 ENST00000338415.3
ENST00000404976.1
QPCT
glutaminyl-peptide cyclotransferase
chr20_-_35329063 1.85 ENST00000422536.1
NDRG3
NDRG family member 3
chr12_+_20963632 1.82 ENST00000540853.1
ENST00000261196.2
SLCO1B3
solute carrier organic anion transporter family, member 1B3
chr2_+_37571845 1.77 ENST00000537448.1
QPCT
glutaminyl-peptide cyclotransferase
chr9_+_80912059 1.72 ENST00000347159.2
ENST00000376588.3
PSAT1
phosphoserine aminotransferase 1
chr14_+_31046959 1.67 ENST00000547532.1
ENST00000555429.1
G2E3
G2/M-phase specific E3 ubiquitin protein ligase
chr9_+_137979506 1.67 ENST00000539529.1
ENST00000392991.4
ENST00000371793.3
OLFM1
olfactomedin 1
chr8_-_81083731 1.67 ENST00000379096.5
TPD52
tumor protein D52
chr15_+_59910132 1.65 ENST00000559200.1
GCNT3
glucosaminyl (N-acetyl) transferase 3, mucin type
chr5_-_16916624 1.64 ENST00000513882.1
MYO10
myosin X
chr10_-_115614127 1.61 ENST00000369305.1
DCLRE1A
DNA cross-link repair 1A
chr11_-_14521349 1.59 ENST00000534234.1
COPB1
coatomer protein complex, subunit beta 1
chr18_+_32558208 1.55 ENST00000436190.2
MAPRE2
microtubule-associated protein, RP/EB family, member 2
chr10_-_13344341 1.45 ENST00000396920.3
PHYH
phytanoyl-CoA 2-hydroxylase
chr12_-_15815626 1.45 ENST00000540613.1
EPS8
epidermal growth factor receptor pathway substrate 8
chr7_-_156685841 1.44 ENST00000354505.4
ENST00000540390.1
LMBR1
limb development membrane protein 1
chr22_-_38240316 1.43 ENST00000411961.2
ENST00000434930.1
ANKRD54
ankyrin repeat domain 54
chr5_-_139930713 1.43 ENST00000602657.1
SRA1
steroid receptor RNA activator 1
chr9_-_98189055 1.41 ENST00000433644.2
RP11-435O5.2
RP11-435O5.2
chr1_+_157963063 1.37 ENST00000360089.4
ENST00000368173.3
ENST00000392272.2
KIRREL
kin of IRRE like (Drosophila)
chr16_+_56782118 1.37 ENST00000566678.1
NUP93
nucleoporin 93kDa
chr1_-_212965104 1.37 ENST00000422588.2
ENST00000366975.6
ENST00000366977.3
ENST00000366976.1
NSL1
NSL1, MIS12 kinetochore complex component
chr8_-_17555164 1.35 ENST00000297488.6
MTUS1
microtubule associated tumor suppressor 1
chr9_-_95055923 1.34 ENST00000430417.1
IARS
isoleucyl-tRNA synthetase
chr12_+_25348139 1.34 ENST00000557540.2
ENST00000381356.4
LYRM5
LYR motif containing 5
chr16_-_12897642 1.34 ENST00000433677.2
ENST00000261660.4
ENST00000381774.4
CPPED1
calcineurin-like phosphoesterase domain containing 1
chr12_+_25348186 1.33 ENST00000555711.1
ENST00000556885.1
ENST00000554266.1
ENST00000556351.1
ENST00000556927.1
ENST00000556402.1
ENST00000553788.1
LYRM5
LYR motif containing 5
chr2_-_200715834 1.29 ENST00000420128.1
ENST00000416668.1
FTCDNL1
formiminotransferase cyclodeaminase N-terminal like
chr8_-_62602327 1.27 ENST00000445642.3
ENST00000517847.2
ENST00000389204.4
ENST00000517661.1
ENST00000517903.1
ENST00000522603.1
ENST00000522349.1
ENST00000522835.1
ENST00000541428.1
ENST00000518306.1
ASPH
aspartate beta-hydroxylase
chr12_-_90049828 1.26 ENST00000261173.2
ENST00000348959.3
ATP2B1
ATPase, Ca++ transporting, plasma membrane 1
chr5_+_61874562 1.26 ENST00000334994.5
ENST00000409534.1
LRRC70
IPO11
leucine rich repeat containing 70
importin 11
chr19_-_48759119 1.25 ENST00000522889.1
ENST00000520753.1
ENST00000519940.1
ENST00000519332.1
ENST00000521437.1
ENST00000520007.1
ENST00000521613.1
CARD8
caspase recruitment domain family, member 8
chr2_+_161993465 1.24 ENST00000457476.1
TANK
TRAF family member-associated NFKB activator
chr2_+_109237717 1.24 ENST00000409441.1
LIMS1
LIM and senescent cell antigen-like domains 1
chr12_-_63328817 1.23 ENST00000228705.6
PPM1H
protein phosphatase, Mg2+/Mn2+ dependent, 1H
chr2_+_143635222 1.19 ENST00000375773.2
ENST00000409512.1
ENST00000410015.2
KYNU
kynureninase
chr17_-_34257731 1.19 ENST00000431884.2
ENST00000425909.3
ENST00000394528.3
ENST00000430160.2
RDM1
RAD52 motif 1
chr11_+_125496619 1.19 ENST00000532669.1
ENST00000278916.3
CHEK1
checkpoint kinase 1
chr8_-_17579726 1.19 ENST00000381861.3
MTUS1
microtubule associated tumor suppressor 1
chr8_+_104033296 1.18 ENST00000521514.1
ENST00000518738.1
ATP6V1C1
ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1
chr12_-_90049878 1.16 ENST00000359142.3
ATP2B1
ATPase, Ca++ transporting, plasma membrane 1
chr10_+_5238793 1.14 ENST00000263126.1
AKR1C4
aldo-keto reductase family 1, member C4
chr1_+_220863187 1.12 ENST00000294889.5
C1orf115
chromosome 1 open reading frame 115
chr9_-_95055956 1.11 ENST00000375629.3
ENST00000447699.2
ENST00000375643.3
ENST00000395554.3
IARS
isoleucyl-tRNA synthetase
chr15_+_40987327 1.11 ENST00000423169.2
ENST00000267868.3
ENST00000557850.1
ENST00000532743.1
ENST00000382643.3
RAD51
RAD51 recombinase
chr12_-_31743901 1.10 ENST00000354285.4
DENND5B
DENN/MADD domain containing 5B
chr1_+_157963391 1.10 ENST00000359209.6
ENST00000416935.2
KIRREL
kin of IRRE like (Drosophila)
chr11_+_125496400 1.09 ENST00000524737.1
CHEK1
checkpoint kinase 1
chr10_-_27529486 1.09 ENST00000375888.1
ACBD5
acyl-CoA binding domain containing 5
chr10_-_123687497 1.08 ENST00000369040.3
ENST00000224652.6
ENST00000369043.3
ATE1
arginyltransferase 1
chr20_+_5987890 1.07 ENST00000378868.4
CRLS1
cardiolipin synthase 1
chr2_+_109204909 1.06 ENST00000393310.1
LIMS1
LIM and senescent cell antigen-like domains 1
chr15_+_52155001 1.05 ENST00000544199.1
TMOD3
tropomodulin 3 (ubiquitous)
chr16_+_19619083 1.04 ENST00000538552.1
C16orf62
chromosome 16 open reading frame 62
chr2_+_38177575 1.02 ENST00000407257.1
ENST00000417700.2
ENST00000234195.3
ENST00000442857.1
RMDN2
regulator of microtubule dynamics 2
chr19_-_48753064 1.00 ENST00000520153.1
ENST00000357778.5
ENST00000520015.1
CARD8
caspase recruitment domain family, member 8
chr7_+_64838712 0.99 ENST00000328747.7
ENST00000431504.1
ENST00000357512.2
ZNF92
zinc finger protein 92
chr8_-_80993010 0.99 ENST00000537855.1
ENST00000520527.1
ENST00000517427.1
ENST00000448733.2
ENST00000379097.3
TPD52
tumor protein D52
chr5_-_65018834 0.97 ENST00000506816.1
SGTB
small glutamine-rich tetratricopeptide repeat (TPR)-containing, beta
chr2_+_109271481 0.97 ENST00000542845.1
ENST00000393314.2
LIMS1
LIM and senescent cell antigen-like domains 1
chr4_+_169633310 0.97 ENST00000510998.1
PALLD
palladin, cytoskeletal associated protein
chr7_-_76955563 0.97 ENST00000441833.2
GSAP
gamma-secretase activating protein
chr17_-_42767092 0.94 ENST00000588687.1
CCDC43
coiled-coil domain containing 43
chr1_-_26231589 0.93 ENST00000374291.1
STMN1
stathmin 1
chr12_-_110906027 0.93 ENST00000537466.2
ENST00000550974.1
ENST00000228827.3
GPN3
GPN-loop GTPase 3
chr9_-_15472730 0.90 ENST00000481862.1
PSIP1
PC4 and SFRS1 interacting protein 1
chr3_-_134092561 0.89 ENST00000510560.1
ENST00000504234.1
ENST00000515172.1
AMOTL2
angiomotin like 2
chr9_-_95056010 0.89 ENST00000443024.2
IARS
isoleucyl-tRNA synthetase
chr18_+_3466248 0.88 ENST00000581029.1
ENST00000581442.1
ENST00000579007.1
RP11-838N2.4
RP11-838N2.4
chr9_-_37384431 0.88 ENST00000452923.1
RP11-397D12.4
RP11-397D12.4
chr2_+_62132800 0.87 ENST00000538736.1
COMMD1
copper metabolism (Murr1) domain containing 1
chr7_+_130126165 0.87 ENST00000427521.1
ENST00000416162.2
ENST00000378576.4
MEST
mesoderm specific transcript
chr2_+_160590469 0.86 ENST00000409591.1
MARCH7
membrane-associated ring finger (C3HC4) 7, E3 ubiquitin protein ligase
chrX_+_120181457 0.86 ENST00000328078.1
GLUD2
glutamate dehydrogenase 2
chr14_+_55494323 0.85 ENST00000339298.2
SOCS4
suppressor of cytokine signaling 4
chr15_+_101459420 0.83 ENST00000388948.3
ENST00000284395.5
ENST00000534045.1
ENST00000532029.2
LRRK1
leucine-rich repeat kinase 1
chr10_+_67330096 0.82 ENST00000433152.4
ENST00000601979.1
ENST00000599409.1
ENST00000608678.1
RP11-222A11.1
RP11-222A11.1
chr7_+_7196565 0.81 ENST00000429911.1
C1GALT1
core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase, 1
chr3_+_69811858 0.80 ENST00000433517.1
MITF
microphthalmia-associated transcription factor
chr13_-_30424821 0.80 ENST00000380680.4
UBL3
ubiquitin-like 3
chr8_+_16884740 0.80 ENST00000318063.5
MICU3
mitochondrial calcium uptake family, member 3
chr12_+_113354341 0.80 ENST00000553152.1
OAS1
2'-5'-oligoadenylate synthetase 1, 40/46kDa
chr1_+_221051699 0.80 ENST00000366903.6
HLX
H2.0-like homeobox
chr7_+_130126012 0.80 ENST00000341441.5
MEST
mesoderm specific transcript
chr1_+_26798955 0.79 ENST00000361427.5
HMGN2
high mobility group nucleosomal binding domain 2
chr2_+_109204743 0.79 ENST00000332345.6
LIMS1
LIM and senescent cell antigen-like domains 1
chr12_-_15374343 0.78 ENST00000256953.2
ENST00000546331.1
RERG
RAS-like, estrogen-regulated, growth inhibitor
chr17_+_33914276 0.78 ENST00000592545.1
ENST00000538556.1
ENST00000312678.8
ENST00000589344.1
AP2B1
adaptor-related protein complex 2, beta 1 subunit
chr2_+_172309634 0.78 ENST00000339506.3
DCAF17
DDB1 and CUL4 associated factor 17
chr2_+_207630081 0.77 ENST00000236980.6
ENST00000418289.1
ENST00000402774.3
ENST00000403094.3
FASTKD2
FAST kinase domains 2
chr2_-_17981462 0.77 ENST00000402989.1
ENST00000428868.1
SMC6
structural maintenance of chromosomes 6
chr17_+_67498396 0.77 ENST00000588110.1
MAP2K6
mitogen-activated protein kinase kinase 6
chr3_+_112709804 0.76 ENST00000383677.3
GTPBP8
GTP-binding protein 8 (putative)
chr5_+_156696362 0.76 ENST00000377576.3
CYFIP2
cytoplasmic FMR1 interacting protein 2
chr10_-_94257512 0.75 ENST00000371581.5
IDE
insulin-degrading enzyme
chr8_+_76452097 0.75 ENST00000396423.2
HNF4G
hepatocyte nuclear factor 4, gamma
chr8_+_104033277 0.75 ENST00000518857.1
ENST00000395862.3
ATP6V1C1
ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1
chr16_-_74734742 0.74 ENST00000308807.7
ENST00000573267.1
MLKL
mixed lineage kinase domain-like
chr17_-_34257771 0.74 ENST00000394529.3
ENST00000293273.6
RDM1
RAD52 motif 1
chr12_-_118628315 0.74 ENST00000540561.1
TAOK3
TAO kinase 3
chr19_-_48753028 0.74 ENST00000522431.1
CARD8
caspase recruitment domain family, member 8
chr10_+_115614370 0.74 ENST00000369301.3
NHLRC2
NHL repeat containing 2
chr14_+_52327350 0.74 ENST00000555472.1
ENST00000556766.1
GNG2
guanine nucleotide binding protein (G protein), gamma 2
chr14_+_39944025 0.73 ENST00000554328.1
ENST00000556620.1
ENST00000557197.1
RP11-111A21.1
RP11-111A21.1
chr14_+_100240019 0.73 ENST00000556199.1
EML1
echinoderm microtubule associated protein like 1
chrX_+_150565653 0.73 ENST00000330374.6
VMA21
VMA21 vacuolar H+-ATPase homolog (S. cerevisiae)
chr13_+_24844857 0.73 ENST00000409126.1
ENST00000343003.6
SPATA13
spermatogenesis associated 13
chr4_+_106631966 0.72 ENST00000360505.5
ENST00000510865.1
ENST00000509336.1
GSTCD
glutathione S-transferase, C-terminal domain containing
chr10_-_123687431 0.72 ENST00000423243.1
ATE1
arginyltransferase 1
chr7_+_64838786 0.72 ENST00000450302.2
ZNF92
zinc finger protein 92
chr7_-_156685890 0.71 ENST00000353442.5
LMBR1
limb development membrane protein 1
chr14_+_20187174 0.71 ENST00000557414.1
OR4N2
olfactory receptor, family 4, subfamily N, member 2
chr21_+_30673091 0.71 ENST00000447177.1
BACH1
BTB and CNC homology 1, basic leucine zipper transcription factor 1
chr18_-_74839891 0.70 ENST00000581878.1
MBP
myelin basic protein
chr14_+_53173890 0.70 ENST00000445930.2
PSMC6
proteasome (prosome, macropain) 26S subunit, ATPase, 6
chr6_-_26189304 0.69 ENST00000340756.2
HIST1H4D
histone cluster 1, H4d
chr17_+_44803922 0.69 ENST00000465370.1
NSF
N-ethylmaleimide-sensitive factor
chr19_-_55677920 0.69 ENST00000524407.2
ENST00000526003.1
ENST00000534170.1
DNAAF3
dynein, axonemal, assembly factor 3
chr12_+_104235229 0.67 ENST00000551650.1
RP11-650K20.3
Uncharacterized protein
chr2_+_128458514 0.67 ENST00000310981.4
SFT2D3
SFT2 domain containing 3
chr19_-_46105411 0.65 ENST00000323040.4
ENST00000544371.1
GPR4
OPA3
G protein-coupled receptor 4
optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
chr14_+_60712463 0.65 ENST00000325642.3
ENST00000529574.1
PPM1A
protein phosphatase, Mg2+/Mn2+ dependent, 1A
chr6_+_32812568 0.63 ENST00000414474.1
PSMB9
proteasome (prosome, macropain) subunit, beta type, 9
chr19_-_55677999 0.63 ENST00000532817.1
ENST00000527223.2
ENST00000391720.4
DNAAF3
dynein, axonemal, assembly factor 3
chr16_+_58074069 0.61 ENST00000570065.1
MMP15
matrix metallopeptidase 15 (membrane-inserted)
chr19_-_48752812 0.61 ENST00000359009.4
CARD8
caspase recruitment domain family, member 8
chr2_-_69664586 0.60 ENST00000303698.3
ENST00000394305.1
ENST00000410022.2
NFU1
NFU1 iron-sulfur cluster scaffold homolog (S. cerevisiae)
chr5_-_16738451 0.60 ENST00000274203.9
ENST00000515803.1
MYO10
myosin X
chrX_-_119077695 0.60 ENST00000371410.3
NKAP
NFKB activating protein
chr2_+_133174147 0.60 ENST00000329321.3
GPR39
G protein-coupled receptor 39
chr11_+_92085262 0.59 ENST00000298047.6
ENST00000409404.2
ENST00000541502.1
FAT3
FAT atypical cadherin 3
chr10_-_123687399 0.59 ENST00000543447.1
ATE1
arginyltransferase 1
chr11_+_125496124 0.58 ENST00000533778.2
ENST00000534070.1
CHEK1
checkpoint kinase 1
chr7_-_111424506 0.56 ENST00000450156.1
ENST00000494651.2
DOCK4
dedicator of cytokinesis 4
chr6_-_109702885 0.56 ENST00000504373.1
CD164
CD164 molecule, sialomucin
chr19_+_30433372 0.55 ENST00000312051.6
URI1
URI1, prefoldin-like chaperone
chr22_+_22676808 0.55 ENST00000390290.2
IGLV1-51
immunoglobulin lambda variable 1-51
chr6_-_111804905 0.54 ENST00000358835.3
ENST00000435970.1
REV3L
REV3-like, polymerase (DNA directed), zeta, catalytic subunit
chr17_-_38956205 0.53 ENST00000306658.7
KRT28
keratin 28
chr6_-_135424186 0.53 ENST00000529882.1
HBS1L
HBS1-like (S. cerevisiae)
chr19_-_48753104 0.52 ENST00000447740.2
CARD8
caspase recruitment domain family, member 8
chrX_-_131353461 0.52 ENST00000370874.1
RAP2C
RAP2C, member of RAS oncogene family
chr17_+_55162453 0.52 ENST00000575322.1
ENST00000337714.3
ENST00000314126.3
AKAP1
A kinase (PRKA) anchor protein 1
chrX_+_123097014 0.51 ENST00000394478.1
STAG2
stromal antigen 2
chr8_-_93978309 0.51 ENST00000517858.1
ENST00000378861.5
TRIQK
triple QxxK/R motif containing
chr8_-_93978333 0.50 ENST00000524037.1
ENST00000520430.1
ENST00000521617.1
TRIQK
triple QxxK/R motif containing
chrX_-_16887963 0.50 ENST00000380084.4
RBBP7
retinoblastoma binding protein 7
chr13_-_24007815 0.50 ENST00000382298.3
SACS
spastic ataxia of Charlevoix-Saguenay (sacsin)
chr3_+_69812701 0.50 ENST00000472437.1
MITF
microphthalmia-associated transcription factor
chr3_+_143690640 0.50 ENST00000315691.3
C3orf58
chromosome 3 open reading frame 58
chr10_-_113943447 0.50 ENST00000369425.1
ENST00000348367.4
ENST00000423155.1
GPAM
glycerol-3-phosphate acyltransferase, mitochondrial
chrX_+_153775821 0.50 ENST00000263518.6
ENST00000470142.1
ENST00000393549.2
ENST00000455588.2
ENST00000369602.3
IKBKG
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
chr13_+_36050881 0.49 ENST00000537702.1
NBEA
neurobeachin
chr11_+_43333513 0.48 ENST00000534695.1
ENST00000455725.2
ENST00000531273.1
ENST00000420461.2
ENST00000378852.3
ENST00000534600.1
API5
apoptosis inhibitor 5
chr3_+_41241596 0.48 ENST00000450969.1
CTNNB1
catenin (cadherin-associated protein), beta 1, 88kDa
chr5_-_145562147 0.48 ENST00000545646.1
ENST00000274562.9
ENST00000510191.1
ENST00000394434.2
LARS
leucyl-tRNA synthetase
chr17_+_12569306 0.48 ENST00000425538.1
MYOCD
myocardin
chr9_-_130889990 0.48 ENST00000449878.1
PTGES2
prostaglandin E synthase 2
chr9_-_138853156 0.47 ENST00000371756.3
UBAC1
UBA domain containing 1
chrX_+_150565038 0.47 ENST00000370361.1
VMA21
VMA21 vacuolar H+-ATPase homolog (S. cerevisiae)
chr19_-_58864848 0.46 ENST00000263100.3
A1BG
alpha-1-B glycoprotein
chr8_-_30670384 0.46 ENST00000221138.4
ENST00000518243.1
PPP2CB
protein phosphatase 2, catalytic subunit, beta isozyme
chrX_+_41193407 0.46 ENST00000457138.2
ENST00000441189.2
DDX3X
DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked
chr11_-_107729287 0.46 ENST00000375682.4
SLC35F2
solute carrier family 35, member F2
chr1_+_81106951 0.45 ENST00000443565.1
RP5-887A10.1
RP5-887A10.1
chr2_+_48541776 0.45 ENST00000413569.1
ENST00000340553.3
FOXN2
forkhead box N2
chr11_-_107729504 0.45 ENST00000265836.7
SLC35F2
solute carrier family 35, member F2
chr12_+_58176525 0.45 ENST00000543727.1
ENST00000540550.1
ENST00000323833.8
ENST00000350762.5
ENST00000550559.1
ENST00000548851.1
ENST00000434359.1
ENST00000457189.1
TSFM
Ts translation elongation factor, mitochondrial
chr16_-_66764119 0.44 ENST00000569320.1
DYNC1LI2
dynein, cytoplasmic 1, light intermediate chain 2
chr3_-_170587815 0.44 ENST00000466674.1
RPL22L1
ribosomal protein L22-like 1
chr12_+_122880045 0.44 ENST00000539034.1
ENST00000535976.1
RP11-450K4.1
RP11-450K4.1
chr3_-_170587974 0.44 ENST00000463836.1
RPL22L1
ribosomal protein L22-like 1
chr12_-_25055177 0.44 ENST00000538118.1
BCAT1
branched chain amino-acid transaminase 1, cytosolic
chr16_+_28505955 0.43 ENST00000564831.1
ENST00000328423.5
ENST00000431282.1
APOBR
apolipoprotein B receptor
chr2_-_200715573 0.43 ENST00000420922.2
FTCDNL1
formiminotransferase cyclodeaminase N-terminal like
chr16_-_74734672 0.43 ENST00000306247.7
ENST00000575686.1
MLKL
mixed lineage kinase domain-like
chr20_-_29896388 0.41 ENST00000400549.1
DEFB116
defensin, beta 116
chr7_-_111424462 0.40 ENST00000437129.1
DOCK4
dedicator of cytokinesis 4
chr17_+_58018269 0.40 ENST00000591035.1
RP11-178C3.1
Uncharacterized protein
chr17_+_42264556 0.40 ENST00000319511.6
ENST00000589785.1
ENST00000592825.1
ENST00000589184.1
TMUB2
transmembrane and ubiquitin-like domain containing 2
chr1_+_241695424 0.40 ENST00000366558.3
ENST00000366559.4
KMO
kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
chr6_-_27782548 0.39 ENST00000333151.3
HIST1H2AJ
histone cluster 1, H2aj
chr3_+_16306691 0.39 ENST00000285083.5
ENST00000605932.1
ENST00000435829.2
OXNAD1
oxidoreductase NAD-binding domain containing 1
chr2_+_202047843 0.38 ENST00000272879.5
ENST00000374650.3
ENST00000346817.5
ENST00000313728.7
ENST00000448480.1
CASP10
caspase 10, apoptosis-related cysteine peptidase

Network of associatons between targets according to the STRING database.

First level regulatory network of HOXC9

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 3.6 GO:0017186 peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase(GO:0017186)
1.2 5.9 GO:0072709 cellular response to sorbitol(GO:0072709)
0.9 2.8 GO:0009786 regulation of asymmetric cell division(GO:0009786)
0.8 3.3 GO:0006428 isoleucyl-tRNA aminoacylation(GO:0006428)
0.6 2.4 GO:0016598 protein arginylation(GO:0016598)
0.5 2.5 GO:1903613 regulation of protein tyrosine phosphatase activity(GO:1903613) positive regulation of protein tyrosine phosphatase activity(GO:1903615)
0.5 2.0 GO:0061763 multivesicular body-lysosome fusion(GO:0061763)
0.5 2.9 GO:0035407 histone H3-T11 phosphorylation(GO:0035407)
0.4 1.6 GO:0002426 immunoglobulin production in mucosal tissue(GO:0002426)
0.3 1.0 GO:1990426 homologous recombination-dependent replication fork processing(GO:1990426)
0.3 1.3 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
0.3 1.2 GO:0019442 tryptophan catabolic process to acetyl-CoA(GO:0019442)
0.3 1.5 GO:0097089 methyl-branched fatty acid metabolic process(GO:0097089)
0.3 1.7 GO:0042816 vitamin B6 metabolic process(GO:0042816)
0.3 2.4 GO:1990034 cellular response to corticosterone stimulus(GO:0071386) calcium ion export from cell(GO:1990034)
0.2 0.7 GO:0000349 generation of catalytic spliceosome for first transesterification step(GO:0000349)
0.2 0.9 GO:1990022 RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022)
0.2 0.8 GO:0016267 O-glycan processing, core 1(GO:0016267)
0.2 2.0 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.2 0.8 GO:0001560 regulation of cell growth by extracellular stimulus(GO:0001560)
0.2 0.8 GO:1901143 insulin catabolic process(GO:1901143)
0.2 1.5 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.2 2.2 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.2 0.5 GO:0006429 glutaminyl-tRNA aminoacylation(GO:0006425) leucyl-tRNA aminoacylation(GO:0006429)
0.2 0.8 GO:1902775 mitochondrial large ribosomal subunit assembly(GO:1902775)
0.2 1.4 GO:0090521 glomerular visceral epithelial cell migration(GO:0090521)
0.1 2.7 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.1 1.1 GO:0071395 response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395)
0.1 0.7 GO:0000117 regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117)
0.1 0.7 GO:0035633 maintenance of blood-brain barrier(GO:0035633)
0.1 1.7 GO:0003190 atrioventricular valve formation(GO:0003190)
0.1 2.3 GO:0050713 negative regulation of interleukin-1 beta secretion(GO:0050713)
0.1 0.9 GO:1905098 negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098)
0.1 3.6 GO:0031915 positive regulation of synaptic plasticity(GO:0031915)
0.1 0.4 GO:0002101 tRNA wobble cytosine modification(GO:0002101) RNA repair(GO:0042245)
0.1 1.1 GO:0030242 pexophagy(GO:0030242)
0.1 1.0 GO:1904694 negative regulation of vascular smooth muscle contraction(GO:1904694)
0.1 0.5 GO:0007403 glial cell fate determination(GO:0007403) canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation(GO:0061324) regulation of chromatin-mediated maintenance of transcription(GO:1904499) positive regulation of chromatin-mediated maintenance of transcription(GO:1904501) regulation of euchromatin binding(GO:1904793)
0.1 2.3 GO:0034501 protein localization to kinetochore(GO:0034501)
0.1 1.1 GO:1904386 response to thyroxine(GO:0097068) response to L-phenylalanine derivative(GO:1904386)
0.1 0.8 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
0.1 1.6 GO:0031848 protection from non-homologous end joining at telomere(GO:0031848)
0.1 0.9 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.1 0.3 GO:0042040 molybdenum incorporation into molybdenum-molybdopterin complex(GO:0018315) metal incorporation into metallo-molybdopterin complex(GO:0042040) glycine receptor clustering(GO:0072579)
0.1 4.3 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.1 1.1 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.1 0.4 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.1 0.3 GO:0071418 cellular response to amine stimulus(GO:0071418)
0.1 0.8 GO:0045629 negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.1 0.3 GO:0002188 translation reinitiation(GO:0002188)
0.1 0.7 GO:0072144 glomerular mesangial cell development(GO:0072144)
0.1 0.6 GO:0006499 N-terminal protein myristoylation(GO:0006499)
0.1 2.2 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.1 0.4 GO:0019805 quinolinate biosynthetic process(GO:0019805)
0.1 4.1 GO:0051894 positive regulation of focal adhesion assembly(GO:0051894)
0.1 0.3 GO:0098905 regulation of bundle of His cell action potential(GO:0098905)
0.1 0.7 GO:0035494 SNARE complex disassembly(GO:0035494)
0.1 0.4 GO:2001170 positive regulation of fat cell proliferation(GO:0070346) negative regulation of ATP biosynthetic process(GO:2001170)
0.1 0.3 GO:0010513 positive regulation of phosphatidylinositol biosynthetic process(GO:0010513)
0.1 0.2 GO:0000961 negative regulation of mitochondrial RNA catabolic process(GO:0000961)
0.1 0.4 GO:0009098 branched-chain amino acid biosynthetic process(GO:0009082) leucine biosynthetic process(GO:0009098) valine biosynthetic process(GO:0009099)
0.1 2.2 GO:0021516 dorsal spinal cord development(GO:0021516)
0.1 0.5 GO:0070370 heat acclimation(GO:0010286) cellular heat acclimation(GO:0070370)
0.1 0.9 GO:0006538 glutamate catabolic process(GO:0006538)
0.1 0.8 GO:0000722 telomere maintenance via recombination(GO:0000722)
0.1 1.3 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.1 0.8 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.1 0.9 GO:0070072 proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.1 0.5 GO:0071651 positive regulation of chemokine (C-C motif) ligand 5 production(GO:0071651)
0.1 1.9 GO:0090383 phagosome acidification(GO:0090383)
0.1 0.5 GO:0070236 negative regulation of activation-induced cell death of T cells(GO:0070236)
0.1 0.4 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.0 1.0 GO:1902004 positive regulation of beta-amyloid formation(GO:1902004)
0.0 0.2 GO:0036509 trimming of terminal mannose on B branch(GO:0036509) trimming of first mannose on A branch(GO:0036511) trimming of second mannose on A branch(GO:0036512)
0.0 0.5 GO:2000270 negative regulation of fibroblast apoptotic process(GO:2000270)
0.0 0.2 GO:1902268 negative regulation of polyamine transmembrane transport(GO:1902268)
0.0 0.3 GO:1903435 positive regulation of constitutive secretory pathway(GO:1903435)
0.0 0.8 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.0 1.0 GO:0045899 positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.0 1.4 GO:0045648 positive regulation of erythrocyte differentiation(GO:0045648)
0.0 0.6 GO:0048245 eosinophil chemotaxis(GO:0048245)
0.0 1.3 GO:2000144 positive regulation of DNA-templated transcription, initiation(GO:2000144)
0.0 0.9 GO:0002643 regulation of tolerance induction(GO:0002643)
0.0 4.1 GO:0042246 tissue regeneration(GO:0042246)
0.0 1.3 GO:0044458 motile cilium assembly(GO:0044458)
0.0 0.5 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
0.0 1.0 GO:0003334 keratinocyte development(GO:0003334)
0.0 0.2 GO:0030950 establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.0 0.4 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.0 0.1 GO:0070327 thyroid hormone transport(GO:0070327)
0.0 1.2 GO:0070207 protein homotrimerization(GO:0070207)
0.0 0.8 GO:0006851 mitochondrial calcium ion transport(GO:0006851)
0.0 0.1 GO:2000296 negative regulation of hydrogen peroxide catabolic process(GO:2000296)
0.0 0.4 GO:0070129 regulation of mitochondrial translation(GO:0070129)
0.0 3.0 GO:0007588 excretion(GO:0007588)
0.0 0.4 GO:0034447 very-low-density lipoprotein particle clearance(GO:0034447)
0.0 0.5 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
0.0 0.5 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.0 0.5 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.0 2.3 GO:0042733 embryonic digit morphogenesis(GO:0042733)
0.0 0.1 GO:0046292 formaldehyde metabolic process(GO:0046292)
0.0 0.6 GO:0031163 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.0 0.3 GO:2000269 regulation of fibroblast apoptotic process(GO:2000269)
0.0 0.1 GO:0050917 sensory perception of umami taste(GO:0050917)
0.0 1.6 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.0 0.8 GO:0036035 osteoclast development(GO:0036035)
0.0 0.3 GO:0006108 malate metabolic process(GO:0006108)
0.0 1.0 GO:0044364 killing of cells of other organism(GO:0031640) disruption of cells of other organism(GO:0044364)
0.0 0.1 GO:0031296 B cell costimulation(GO:0031296)
0.0 0.1 GO:0061534 gamma-aminobutyric acid secretion, neurotransmission(GO:0061534)
0.0 0.6 GO:0071380 cellular response to prostaglandin E stimulus(GO:0071380)
0.0 0.4 GO:0060009 Sertoli cell development(GO:0060009)
0.0 0.1 GO:0070101 positive regulation of chemokine-mediated signaling pathway(GO:0070101)
0.0 0.1 GO:0048630 skeletal muscle tissue growth(GO:0048630)
0.0 1.1 GO:0050982 detection of mechanical stimulus(GO:0050982)
0.0 2.8 GO:0002433 immune response-regulating cell surface receptor signaling pathway involved in phagocytosis(GO:0002433) Fc-gamma receptor signaling pathway involved in phagocytosis(GO:0038096)
0.0 0.7 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.0 0.1 GO:0033206 meiotic cytokinesis(GO:0033206) polar body extrusion after meiotic divisions(GO:0040038) formin-nucleated actin cable assembly(GO:0070649)
0.0 0.2 GO:1902894 negative regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902894)
0.0 0.6 GO:0071425 hematopoietic stem cell proliferation(GO:0071425)
0.0 0.2 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.0 0.2 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
0.0 2.3 GO:0030183 B cell differentiation(GO:0030183)
0.0 0.2 GO:0006449 regulation of translational termination(GO:0006449)
0.0 0.5 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.0 0.9 GO:0035329 hippo signaling(GO:0035329)
0.0 0.1 GO:0006041 glucosamine metabolic process(GO:0006041)
0.0 0.8 GO:2000273 positive regulation of receptor activity(GO:2000273)
0.0 0.1 GO:1901857 positive regulation of cellular respiration(GO:1901857)
0.0 0.3 GO:1904380 endoplasmic reticulum mannose trimming(GO:1904380)
0.0 0.7 GO:1904837 beta-catenin-TCF complex assembly(GO:1904837)
0.0 0.4 GO:0046339 diacylglycerol metabolic process(GO:0046339)
0.0 0.3 GO:0006517 protein deglycosylation(GO:0006517)
0.0 0.7 GO:0034198 cellular response to amino acid starvation(GO:0034198)
0.0 0.2 GO:0048227 plasma membrane to endosome transport(GO:0048227)
0.0 0.2 GO:0007379 segment specification(GO:0007379) positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.0 0.2 GO:0036148 phosphatidylglycerol acyl-chain remodeling(GO:0036148)
0.0 0.7 GO:0007405 neuroblast proliferation(GO:0007405)
0.0 2.5 GO:0030308 negative regulation of cell growth(GO:0030308)
0.0 0.5 GO:0043276 anoikis(GO:0043276)
0.0 1.7 GO:0007062 sister chromatid cohesion(GO:0007062)
0.0 0.9 GO:0006893 Golgi to plasma membrane transport(GO:0006893)
0.0 0.5 GO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.0 0.1 GO:0046092 deoxycytidine metabolic process(GO:0046092)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 3.6 GO:0070033 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033) synaptobrevin 2-SNAP-25-syntaxin-3-complexin complex(GO:0070554)
0.3 1.9 GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221)
0.3 1.4 GO:0000444 MIS12/MIND type complex(GO:0000444)
0.2 2.8 GO:0072687 meiotic spindle(GO:0072687)
0.2 0.7 GO:0071006 U2-type catalytic step 1 spliceosome(GO:0071006)
0.2 3.8 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.1 2.3 GO:0072559 NLRP3 inflammasome complex(GO:0072559)
0.1 2.3 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.1 2.1 GO:0030126 COPI vesicle coat(GO:0030126)
0.1 1.3 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.1 2.0 GO:0000815 ESCRT III complex(GO:0000815)
0.1 0.8 GO:0035061 interchromatin granule(GO:0035061)
0.1 2.2 GO:0032433 filopodium tip(GO:0032433)
0.1 2.4 GO:0032591 dendritic spine membrane(GO:0032591)
0.1 0.5 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.1 1.0 GO:0031595 nuclear proteasome complex(GO:0031595)
0.1 0.6 GO:1990111 spermatoproteasome complex(GO:1990111)
0.1 0.2 GO:0005602 complement component C1 complex(GO:0005602)
0.1 0.8 GO:0031597 cytosolic proteasome complex(GO:0031597)
0.1 3.4 GO:0035371 microtubule plus-end(GO:0035371)
0.1 1.5 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.1 0.5 GO:0070369 Scrib-APC-beta-catenin complex(GO:0034750) beta-catenin-TCF7L2 complex(GO:0070369)
0.1 0.5 GO:0070852 cell body fiber(GO:0070852)
0.1 0.7 GO:0033269 internode region of axon(GO:0033269)
0.0 1.2 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.0 1.7 GO:0044295 axonal growth cone(GO:0044295)
0.0 1.0 GO:0000800 lateral element(GO:0000800)
0.0 0.7 GO:1990023 mitotic spindle midzone(GO:1990023)
0.0 3.6 GO:0035580 specific granule lumen(GO:0035580)
0.0 2.2 GO:0045171 intercellular bridge(GO:0045171)
0.0 2.9 GO:0000794 condensed nuclear chromosome(GO:0000794)
0.0 0.9 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.0 0.8 GO:0036020 endolysosome membrane(GO:0036020)
0.0 2.0 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.3 GO:0030134 ER to Golgi transport vesicle(GO:0030134)
0.0 1.4 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 0.4 GO:0042627 chylomicron(GO:0042627)
0.0 0.5 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0 0.5 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 0.8 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 0.4 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.2 GO:0042382 paraspeckles(GO:0042382)
0.0 0.2 GO:0061700 GATOR2 complex(GO:0061700)
0.0 0.5 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.0 0.2 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 0.4 GO:0071564 npBAF complex(GO:0071564)
0.0 2.3 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 0.1 GO:0043541 UDP-N-acetylglucosamine transferase complex(GO:0043541)
0.0 0.8 GO:0032420 stereocilium(GO:0032420)
0.0 0.1 GO:0035859 Seh1-associated complex(GO:0035859)
0.0 0.3 GO:0031045 dense core granule(GO:0031045)
0.0 0.5 GO:0090545 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 1.0 GO:0002102 podosome(GO:0002102)
0.0 0.4 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 1.4 GO:0043657 host(GO:0018995) host cell(GO:0043657)
0.0 1.4 GO:0035578 azurophil granule lumen(GO:0035578)
0.0 0.1 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.0 1.1 GO:0031903 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 0.2 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.2 GO:0031932 TORC2 complex(GO:0031932)
0.0 1.2 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 3.6 GO:0016603 glutaminyl-peptide cyclotransferase activity(GO:0016603)
0.8 3.3 GO:0004822 isoleucine-tRNA ligase activity(GO:0004822)
0.7 2.2 GO:0019781 NEDD8 activating enzyme activity(GO:0019781)
0.7 4.1 GO:0032089 NACHT domain binding(GO:0032089)
0.6 2.4 GO:0004057 arginyltransferase activity(GO:0004057)
0.5 1.6 GO:0047225 acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0047225)
0.5 1.5 GO:0048244 phytanoyl-CoA dioxygenase activity(GO:0048244)
0.5 2.9 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
0.4 1.3 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.4 1.1 GO:0008808 cardiolipin synthase activity(GO:0008808) phosphatidyltransferase activity(GO:0030572) CDP-diacylglycerol-phosphatidylglycerol phosphatidyltransferase activity(GO:0043337)
0.3 0.8 GO:0031626 beta-endorphin binding(GO:0031626)
0.2 1.1 GO:0047023 androsterone dehydrogenase activity(GO:0047023)
0.2 2.2 GO:0043515 kinetochore binding(GO:0043515)
0.2 0.9 GO:0016639 oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor(GO:0016639)
0.2 2.2 GO:0060002 plus-end directed microfilament motor activity(GO:0060002)
0.2 0.8 GO:0016263 glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity(GO:0016263)
0.2 1.2 GO:0016823 hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
0.2 1.9 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.2 0.5 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.2 0.5 GO:0004823 glutamine-tRNA ligase activity(GO:0004819) leucine-tRNA ligase activity(GO:0004823)
0.1 4.0 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.1 5.9 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.1 1.6 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.1 0.5 GO:1990450 linear polyubiquitin binding(GO:1990450)
0.1 0.3 GO:0061599 molybdopterin adenylyltransferase activity(GO:0061598) molybdopterin molybdotransferase activity(GO:0061599)
0.1 0.5 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
0.1 1.0 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.1 0.4 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.1 0.3 GO:0000224 peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity(GO:0000224)
0.1 0.3 GO:0004852 uroporphyrinogen-III synthase activity(GO:0004852)
0.1 1.0 GO:0001540 beta-amyloid binding(GO:0001540)
0.1 2.2 GO:0008483 transaminase activity(GO:0008483)
0.1 4.0 GO:0017075 syntaxin-1 binding(GO:0017075)
0.1 0.9 GO:0097100 supercoiled DNA binding(GO:0097100)
0.1 2.4 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.1 0.8 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.1 1.0 GO:0043142 single-stranded DNA-dependent ATPase activity(GO:0043142)
0.1 0.7 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.1 0.4 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.1 2.5 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.1 1.2 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.1 0.4 GO:0030229 very-low-density lipoprotein particle receptor activity(GO:0030229)
0.1 1.3 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 0.4 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.0 0.6 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.0 0.2 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.0 0.7 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.7 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 1.4 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.3 GO:0030060 L-malate dehydrogenase activity(GO:0030060)
0.0 0.1 GO:0015173 aromatic amino acid transmembrane transporter activity(GO:0015173)
0.0 0.5 GO:0033592 RNA strand annealing activity(GO:0033592)
0.0 0.2 GO:0030197 extracellular matrix constituent, lubricant activity(GO:0030197)
0.0 1.1 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.0 0.1 GO:0000035 acyl binding(GO:0000035)
0.0 0.3 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.0 0.2 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.0 0.2 GO:0000386 second spliceosomal transesterification activity(GO:0000386)
0.0 1.1 GO:0005523 tropomyosin binding(GO:0005523)
0.0 1.0 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 0.3 GO:0051378 amine binding(GO:0043176) serotonin binding(GO:0051378)
0.0 0.7 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 1.0 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.4 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.0 0.8 GO:0098748 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 0.3 GO:0016713 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen(GO:0016713)
0.0 0.2 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.0 0.6 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.7 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 0.6 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 2.2 GO:0017022 myosin binding(GO:0017022)
0.0 0.1 GO:0098519 nucleotide phosphatase activity, acting on free nucleotides(GO:0098519)
0.0 0.1 GO:0023024 MHC class I protein complex binding(GO:0023024)
0.0 0.6 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 1.1 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
0.0 1.5 GO:0019003 GDP binding(GO:0019003)
0.0 0.4 GO:0045504 dynein heavy chain binding(GO:0045504)
0.0 0.4 GO:0070513 death domain binding(GO:0070513)
0.0 0.9 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.1 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.0 0.5 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 1.8 GO:0048365 Rac GTPase binding(GO:0048365)
0.0 1.4 GO:0070888 E-box binding(GO:0070888)
0.0 0.5 GO:0070628 proteasome binding(GO:0070628)
0.0 0.2 GO:0047144 2-acylglycerol-3-phosphate O-acyltransferase activity(GO:0047144)
0.0 0.1 GO:0030492 hemoglobin binding(GO:0030492)
0.0 0.3 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0 0.2 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0 0.8 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 0.8 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 0.4 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.2 GO:0033038 bitter taste receptor activity(GO:0033038)
0.0 0.1 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.0 0.4 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 1.7 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 0.6 GO:0042056 chemoattractant activity(GO:0042056)
0.0 0.5 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.0 1.1 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.0 GO:0005148 prolactin receptor binding(GO:0005148)
0.0 0.4 GO:0005248 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0 0.2 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
0.0 0.1 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.0 0.2 GO:0031543 peptidyl-proline dioxygenase activity(GO:0031543)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 6.8 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.2 2.9 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.1 0.5 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.0 4.4 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 3.5 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 0.5 PID IFNG PATHWAY IFN-gamma pathway
0.0 2.5 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 0.7 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.0 2.5 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.0 1.2 ST INTERLEUKIN 4 PATHWAY Interleukin 4 (IL-4) Pathway
0.0 1.5 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 1.0 PID ATR PATHWAY ATR signaling pathway
0.0 0.6 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.7 PID TRAIL PATHWAY TRAIL signaling pathway
0.0 1.3 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 0.2 PID MYC PATHWAY C-MYC pathway
0.0 1.9 PID CMYB PATHWAY C-MYB transcription factor network
0.0 2.5 PID PDGFRB PATHWAY PDGFR-beta signaling pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.9 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.1 6.4 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.1 2.9 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.1 1.6 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.1 0.9 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.1 3.7 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.1 3.8 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.1 2.5 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.1 0.9 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.1 1.3 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.1 1.6 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.1 1.9 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.1 1.7 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 2.0 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 4.9 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 1.5 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.0 0.8 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.0 2.4 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 1.0 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0 2.4 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 0.4 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.0 0.5 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 1.4 REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.0 0.7 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0 1.7 REACTOME P53 INDEPENDENT G1 S DNA DAMAGE CHECKPOINT Genes involved in p53-Independent G1/S DNA damage checkpoint
0.0 4.6 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 1.1 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 0.7 REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA Genes involved in G beta:gamma signalling through PLC beta
0.0 0.4 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.0 0.2 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.0 0.2 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.0 0.9 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.5 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 0.6 REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.0 0.7 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.2 REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.0 0.2 REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.0 0.5 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 1.8 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 0.5 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.4 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.2 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.2 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.3 REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins