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SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for HOXD10

Z-value: 0.85

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Transcription factors associated with HOXD10

Gene Symbol Gene ID Gene Info
HOXD10
ENSG00000128710.5 homeobox D10

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HOXD10hg19_v2_chr2_+_176981307_176981307-0.705.5e-04Click!

Activity profile of HOXD10 motif

Sorted Z-values of HOXD10 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr4_-_68749745 2.96 ENST00000283916.6
TMPRSS11D
transmembrane protease, serine 11D
chr18_+_29027696 2.57 ENST00000257189.4
DSG3
desmoglein 3
chr13_+_78109884 2.49 ENST00000377246.3
ENST00000349847.3
SCEL
sciellin
chr18_+_61564389 2.47 ENST00000397996.2
ENST00000418725.1
SERPINB10
serpin peptidase inhibitor, clade B (ovalbumin), member 10
chr13_+_78109804 2.36 ENST00000535157.1
SCEL
sciellin
chr4_-_68749699 2.36 ENST00000545541.1
TMPRSS11D
transmembrane protease, serine 11D
chr2_-_161056762 2.09 ENST00000428609.2
ENST00000409967.2
ITGB6
integrin, beta 6
chr3_+_136676707 1.89 ENST00000329582.4
IL20RB
interleukin 20 receptor beta
chr2_-_161056802 1.80 ENST00000283249.2
ENST00000409872.1
ITGB6
integrin, beta 6
chr14_+_37126765 1.67 ENST00000402703.2
PAX9
paired box 9
chr4_-_90758227 1.63 ENST00000506691.1
ENST00000394986.1
ENST00000506244.1
ENST00000394989.2
ENST00000394991.3
SNCA
synuclein, alpha (non A4 component of amyloid precursor)
chr8_+_95653840 1.59 ENST00000520385.1
ESRP1
epithelial splicing regulatory protein 1
chr3_+_118892411 1.59 ENST00000479520.1
ENST00000494855.1
UPK1B
uroplakin 1B
chr1_+_158978768 1.56 ENST00000447473.2
IFI16
interferon, gamma-inducible protein 16
chr11_-_104827425 1.50 ENST00000393150.3
CASP4
caspase 4, apoptosis-related cysteine peptidase
chr1_+_152975488 1.49 ENST00000542696.1
SPRR3
small proline-rich protein 3
chr19_-_51456321 1.44 ENST00000391809.2
KLK5
kallikrein-related peptidase 5
chr18_+_61445007 1.39 ENST00000447428.1
ENST00000546027.1
SERPINB7
serpin peptidase inhibitor, clade B (ovalbumin), member 7
chr6_-_135375921 1.39 ENST00000367820.2
ENST00000314674.3
ENST00000524715.1
ENST00000415177.2
ENST00000367826.2
HBS1L
HBS1-like (S. cerevisiae)
chr11_-_79151695 1.39 ENST00000278550.7
TENM4
teneurin transmembrane protein 4
chr1_-_111743285 1.38 ENST00000357640.4
DENND2D
DENN/MADD domain containing 2D
chr18_-_68004529 1.36 ENST00000578633.1
RP11-484N16.1
RP11-484N16.1
chr6_-_135375986 1.33 ENST00000525067.1
ENST00000367822.5
ENST00000367837.5
HBS1L
HBS1-like (S. cerevisiae)
chr2_-_214016314 1.30 ENST00000434687.1
ENST00000374319.4
IKZF2
IKAROS family zinc finger 2 (Helios)
chr6_+_36097992 1.29 ENST00000211287.4
MAPK13
mitogen-activated protein kinase 13
chr1_-_153113927 1.27 ENST00000368752.4
SPRR2B
small proline-rich protein 2B
chr11_-_104905840 1.25 ENST00000526568.1
ENST00000393136.4
ENST00000531166.1
ENST00000534497.1
ENST00000527979.1
ENST00000446369.1
ENST00000353247.5
ENST00000528974.1
ENST00000533400.1
ENST00000525825.1
ENST00000436863.3
CASP1
caspase 1, apoptosis-related cysteine peptidase
chr11_+_58938903 1.24 ENST00000532982.1
DTX4
deltex homolog 4 (Drosophila)
chr8_-_112248400 1.12 ENST00000519506.1
ENST00000522778.1
RP11-946L20.4
RP11-946L20.4
chr10_-_28623368 1.11 ENST00000441595.2
MPP7
membrane protein, palmitoylated 7 (MAGUK p55 subfamily member 7)
chr18_+_20494078 1.07 ENST00000579124.1
ENST00000577588.1
ENST00000582354.1
ENST00000581819.1
RBBP8
retinoblastoma binding protein 8
chr3_-_185538849 1.06 ENST00000421047.2
IGF2BP2
insulin-like growth factor 2 mRNA binding protein 2
chr5_+_96211643 1.06 ENST00000437043.3
ENST00000510373.1
ERAP2
endoplasmic reticulum aminopeptidase 2
chr13_+_76378305 1.03 ENST00000526371.1
ENST00000526528.1
LMO7
LIM domain 7
chr15_+_42566384 0.98 ENST00000440615.2
ENST00000318010.8
GANC
glucosidase, alpha; neutral C
chr7_+_90338712 0.98 ENST00000265741.3
ENST00000406263.1
CDK14
cyclin-dependent kinase 14
chr18_-_21891460 0.97 ENST00000357041.4
OSBPL1A
oxysterol binding protein-like 1A
chr18_-_61329118 0.96 ENST00000332821.8
ENST00000283752.5
SERPINB3
serpin peptidase inhibitor, clade B (ovalbumin), member 3
chr2_-_165698662 0.93 ENST00000194871.6
ENST00000445474.2
COBLL1
cordon-bleu WH2 repeat protein-like 1
chr12_+_48876275 0.93 ENST00000314014.2
C12orf54
chromosome 12 open reading frame 54
chr3_+_136649311 0.93 ENST00000469404.1
ENST00000467911.1
NCK1
NCK adaptor protein 1
chr3_-_99569821 0.92 ENST00000487087.1
FILIP1L
filamin A interacting protein 1-like
chr12_-_48164812 0.92 ENST00000549151.1
ENST00000548919.1
RAPGEF3
Rap guanine nucleotide exchange factor (GEF) 3
chr4_-_90756769 0.91 ENST00000345009.4
ENST00000505199.1
ENST00000502987.1
SNCA
synuclein, alpha (non A4 component of amyloid precursor)
chr4_-_187517928 0.91 ENST00000512772.1
FAT1
FAT atypical cadherin 1
chr4_-_153332886 0.90 ENST00000603841.1
FBXW7
F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
chr3_-_69249863 0.90 ENST00000478263.1
ENST00000462512.1
FRMD4B
FERM domain containing 4B
chr11_-_18258342 0.90 ENST00000278222.4
SAA4
serum amyloid A4, constitutive
chr2_+_210444748 0.90 ENST00000392194.1
MAP2
microtubule-associated protein 2
chr5_-_39203093 0.88 ENST00000515010.1
FYB
FYN binding protein
chr14_+_51955831 0.87 ENST00000356218.4
FRMD6
FERM domain containing 6
chr14_+_57671888 0.87 ENST00000391612.1
AL391152.1
AL391152.1
chrX_+_15808569 0.86 ENST00000380308.3
ENST00000307771.7
ZRSR2
zinc finger (CCCH type), RNA-binding motif and serine/arginine rich 2
chr4_-_102268708 0.85 ENST00000525819.1
PPP3CA
protein phosphatase 3, catalytic subunit, alpha isozyme
chr4_+_71384257 0.85 ENST00000339336.4
AMTN
amelotin
chr18_+_61445205 0.85 ENST00000431370.1
SERPINB7
serpin peptidase inhibitor, clade B (ovalbumin), member 7
chr14_+_75988768 0.84 ENST00000286639.6
BATF
basic leucine zipper transcription factor, ATF-like
chr11_-_104972158 0.82 ENST00000598974.1
ENST00000593315.1
ENST00000594519.1
ENST00000415981.2
ENST00000525374.1
ENST00000375707.1
CASP1
CARD16
CARD17
caspase 1, apoptosis-related cysteine peptidase
caspase recruitment domain family, member 16
caspase recruitment domain family, member 17
chr2_+_102456277 0.79 ENST00000421882.1
MAP4K4
mitogen-activated protein kinase kinase kinase kinase 4
chr1_+_117963209 0.78 ENST00000449370.2
MAN1A2
mannosidase, alpha, class 1A, member 2
chr17_-_4463856 0.78 ENST00000574584.1
ENST00000381550.3
ENST00000301395.3
GGT6
gamma-glutamyltransferase 6
chr3_-_93747425 0.77 ENST00000315099.2
STX19
syntaxin 19
chr10_+_13141585 0.77 ENST00000378764.2
OPTN
optineurin
chr7_+_90339169 0.75 ENST00000436577.2
CDK14
cyclin-dependent kinase 14
chr14_-_36990354 0.75 ENST00000518149.1
NKX2-1
NK2 homeobox 1
chr8_-_101718991 0.73 ENST00000517990.1
PABPC1
poly(A) binding protein, cytoplasmic 1
chr17_+_48610074 0.73 ENST00000503690.1
ENST00000514874.1
ENST00000537145.1
ENST00000541226.1
EPN3
epsin 3
chr12_-_9102224 0.73 ENST00000543845.1
ENST00000544245.1
M6PR
mannose-6-phosphate receptor (cation dependent)
chr10_+_5488564 0.72 ENST00000449083.1
ENST00000380359.3
NET1
neuroepithelial cell transforming 1
chr3_-_195310802 0.70 ENST00000421243.1
ENST00000453131.1
APOD
apolipoprotein D
chr1_+_174844645 0.70 ENST00000486220.1
RABGAP1L
RAB GTPase activating protein 1-like
chr3_+_57882061 0.69 ENST00000461354.1
ENST00000466255.1
SLMAP
sarcolemma associated protein
chr5_+_145583107 0.65 ENST00000506502.1
RBM27
RNA binding motif protein 27
chr1_+_40810516 0.64 ENST00000435168.2
SMAP2
small ArfGAP2
chr7_+_134551583 0.64 ENST00000435928.1
CALD1
caldesmon 1
chr4_-_76944621 0.64 ENST00000306602.1
CXCL10
chemokine (C-X-C motif) ligand 10
chr14_+_37131058 0.64 ENST00000361487.6
PAX9
paired box 9
chr5_-_137475071 0.63 ENST00000265191.2
NME5
NME/NM23 family member 5
chr1_+_14075903 0.63 ENST00000343137.4
ENST00000503842.1
ENST00000407521.3
ENST00000505823.1
PRDM2
PR domain containing 2, with ZNF domain
chr19_-_6690723 0.62 ENST00000601008.1
C3
complement component 3
chr1_+_79115503 0.62 ENST00000370747.4
ENST00000438486.1
ENST00000545124.1
IFI44
interferon-induced protein 44
chr17_+_67759813 0.61 ENST00000587241.1
AC003051.1
AC003051.1
chr3_-_56950407 0.61 ENST00000496106.1
ARHGEF3
Rho guanine nucleotide exchange factor (GEF) 3
chr7_+_132937820 0.61 ENST00000393161.2
ENST00000253861.4
EXOC4
exocyst complex component 4
chr13_+_76378357 0.60 ENST00000489941.2
ENST00000525373.1
LMO7
LIM domain 7
chr4_+_71384300 0.60 ENST00000504451.1
AMTN
amelotin
chr6_+_145118873 0.60 ENST00000432686.1
ENST00000417142.1
UTRN
utrophin
chr14_+_72064945 0.60 ENST00000537413.1
SIPA1L1
signal-induced proliferation-associated 1 like 1
chr3_+_196466710 0.59 ENST00000327134.3
PAK2
p21 protein (Cdc42/Rac)-activated kinase 2
chr3_+_177159695 0.59 ENST00000442937.1
LINC00578
long intergenic non-protein coding RNA 578
chr9_+_103189405 0.59 ENST00000395067.2
MSANTD3
Myb/SANT-like DNA-binding domain containing 3
chr12_+_14561422 0.58 ENST00000541056.1
ATF7IP
activating transcription factor 7 interacting protein
chr18_+_55816546 0.58 ENST00000435432.2
ENST00000357895.5
ENST00000586263.1
NEDD4L
neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
chrM_+_10464 0.57 ENST00000361335.1
MT-ND4L
mitochondrially encoded NADH dehydrogenase 4L
chr12_+_118814185 0.57 ENST00000543473.1
SUDS3
suppressor of defective silencing 3 homolog (S. cerevisiae)
chr6_+_147527103 0.57 ENST00000179882.6
STXBP5
syntaxin binding protein 5 (tomosyn)
chr5_+_64064748 0.56 ENST00000381070.3
ENST00000508024.1
CWC27
CWC27 spliceosome-associated protein homolog (S. cerevisiae)
chr6_+_37897735 0.56 ENST00000373389.5
ZFAND3
zinc finger, AN1-type domain 3
chr2_-_74875432 0.55 ENST00000536235.1
ENST00000421985.1
M1AP
meiosis 1 associated protein
chr10_+_116697946 0.55 ENST00000298746.3
TRUB1
TruB pseudouridine (psi) synthase family member 1
chrX_-_102565858 0.55 ENST00000449185.1
ENST00000536889.1
BEX2
brain expressed X-linked 2
chr10_+_13141441 0.55 ENST00000263036.5
OPTN
optineurin
chr17_-_4464081 0.55 ENST00000574154.1
GGT6
gamma-glutamyltransferase 6
chr4_-_102268484 0.55 ENST00000394853.4
PPP3CA
protein phosphatase 3, catalytic subunit, alpha isozyme
chr10_+_13142225 0.54 ENST00000378747.3
OPTN
optineurin
chr9_+_70856397 0.54 ENST00000360171.6
CBWD3
COBW domain containing 3
chr9_+_103189458 0.53 ENST00000398977.2
MSANTD3
Myb/SANT-like DNA-binding domain containing 3
chr2_-_74618907 0.53 ENST00000421392.1
ENST00000437375.1
DCTN1
dynactin 1
chr4_-_47983519 0.52 ENST00000358519.4
ENST00000544810.1
ENST00000402813.3
CNGA1
cyclic nucleotide gated channel alpha 1
chr2_+_90458201 0.52 ENST00000603238.1
CH17-132F21.1
Uncharacterized protein
chr10_-_62332357 0.52 ENST00000503366.1
ANK3
ankyrin 3, node of Ranvier (ankyrin G)
chrM_+_10053 0.52 ENST00000361227.2
MT-ND3
mitochondrially encoded NADH dehydrogenase 3
chr13_+_114567131 0.52 ENST00000608651.1
GAS6-AS2
GAS6 antisense RNA 2 (head to head)
chr4_+_76649797 0.52 ENST00000538159.1
ENST00000514213.2
USO1
USO1 vesicle transport factor
chr3_+_57881966 0.51 ENST00000495364.1
SLMAP
sarcolemma associated protein
chr1_-_95391315 0.51 ENST00000545882.1
ENST00000415017.1
CNN3
calponin 3, acidic
chr3_+_44666519 0.51 ENST00000344387.4
ENST00000383745.2
ZNF197
zinc finger protein 197
chr4_+_87857538 0.50 ENST00000511442.1
AFF1
AF4/FMR2 family, member 1
chr1_-_33642151 0.50 ENST00000543586.1
TRIM62
tripartite motif containing 62
chr6_-_130543958 0.50 ENST00000437477.2
ENST00000439090.2
SAMD3
sterile alpha motif domain containing 3
chr10_-_104913367 0.50 ENST00000423468.2
NT5C2
5'-nucleotidase, cytosolic II
chr1_-_197036364 0.50 ENST00000367412.1
F13B
coagulation factor XIII, B polypeptide
chr11_-_130786333 0.50 ENST00000533214.1
ENST00000528555.1
ENST00000530356.1
ENST00000539184.1
SNX19
sorting nexin 19
chr10_+_11047259 0.49 ENST00000379261.4
ENST00000416382.2
CELF2
CUGBP, Elav-like family member 2
chr3_+_120461484 0.48 ENST00000484715.1
ENST00000469772.1
ENST00000283875.5
ENST00000492959.1
GTF2E1
general transcription factor IIE, polypeptide 1, alpha 56kDa
chr1_+_15986364 0.47 ENST00000345034.1
RSC1A1
regulatory solute carrier protein, family 1, member 1
chr2_+_135809835 0.47 ENST00000264158.8
ENST00000539493.1
ENST00000442034.1
ENST00000425393.1
RAB3GAP1
RAB3 GTPase activating protein subunit 1 (catalytic)
chr3_+_107318157 0.47 ENST00000406780.1
BBX
bobby sox homolog (Drosophila)
chr2_-_188312971 0.46 ENST00000410068.1
ENST00000447403.1
ENST00000410102.1
CALCRL
calcitonin receptor-like
chr6_+_30856507 0.46 ENST00000513240.1
ENST00000424544.2
DDR1
discoidin domain receptor tyrosine kinase 1
chr12_+_118814344 0.46 ENST00000397564.2
SUDS3
suppressor of defective silencing 3 homolog (S. cerevisiae)
chr5_+_54603566 0.46 ENST00000230640.5
SKIV2L2
superkiller viralicidic activity 2-like 2 (S. cerevisiae)
chr21_-_27423339 0.46 ENST00000415997.1
APP
amyloid beta (A4) precursor protein
chr3_-_37216055 0.45 ENST00000336686.4
LRRFIP2
leucine rich repeat (in FLII) interacting protein 2
chr12_-_76817036 0.45 ENST00000546946.1
OSBPL8
oxysterol binding protein-like 8
chr12_+_75784850 0.45 ENST00000550916.1
ENST00000435775.1
ENST00000378689.2
ENST00000378692.3
ENST00000320460.4
ENST00000547164.1
GLIPR1L2
GLI pathogenesis-related 1 like 2
chr13_+_76378407 0.45 ENST00000447038.1
LMO7
LIM domain 7
chr20_+_57467204 0.44 ENST00000603546.1
GNAS
GNAS complex locus
chr2_+_172543919 0.44 ENST00000452242.1
ENST00000340296.4
DYNC1I2
dynein, cytoplasmic 1, intermediate chain 2
chr4_+_100495864 0.44 ENST00000265517.5
ENST00000422897.2
MTTP
microsomal triglyceride transfer protein
chr7_+_93652116 0.44 ENST00000415536.1
AC003092.1
AC003092.1
chr1_-_40042073 0.43 ENST00000372858.3
PABPC4
poly(A) binding protein, cytoplasmic 4 (inducible form)
chrM_+_8366 0.42 ENST00000361851.1
MT-ATP8
mitochondrially encoded ATP synthase 8
chr5_-_41794313 0.42 ENST00000512084.1
OXCT1
3-oxoacid CoA transferase 1
chr1_+_78383813 0.42 ENST00000342754.5
NEXN
nexilin (F actin binding protein)
chr12_-_91546926 0.42 ENST00000550758.1
DCN
decorin
chr11_+_120255997 0.42 ENST00000532993.1
ARHGEF12
Rho guanine nucleotide exchange factor (GEF) 12
chr11_+_122753391 0.42 ENST00000307257.6
ENST00000227349.2
C11orf63
chromosome 11 open reading frame 63
chr17_+_61151306 0.42 ENST00000580068.1
ENST00000580466.1
TANC2
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
chr12_-_10022735 0.42 ENST00000228438.2
CLEC2B
C-type lectin domain family 2, member B
chr8_-_18871159 0.42 ENST00000327040.8
ENST00000440756.2
PSD3
pleckstrin and Sec7 domain containing 3
chrX_-_41449204 0.42 ENST00000378179.3
CASK
calcium/calmodulin-dependent serine protein kinase (MAGUK family)
chr5_+_95997885 0.41 ENST00000511097.2
CAST
calpastatin
chr18_+_48918368 0.41 ENST00000583982.1
ENST00000578152.1
ENST00000583609.1
ENST00000435144.1
ENST00000580841.1
RP11-267C16.1
RP11-267C16.1
chr3_+_57882024 0.40 ENST00000494088.1
SLMAP
sarcolemma associated protein
chr6_-_100016527 0.40 ENST00000523985.1
ENST00000518714.1
ENST00000520371.1
CCNC
cyclin C
chr14_+_75988851 0.40 ENST00000555504.1
BATF
basic leucine zipper transcription factor, ATF-like
chr2_-_122247879 0.40 ENST00000545861.1
CLASP1
cytoplasmic linker associated protein 1
chr3_+_30647994 0.40 ENST00000295754.5
TGFBR2
transforming growth factor, beta receptor II (70/80kDa)
chr1_+_40862501 0.39 ENST00000539317.1
SMAP2
small ArfGAP2
chr6_-_33754778 0.39 ENST00000508327.1
ENST00000513701.1
LEMD2
LEM domain containing 2
chrX_+_107334983 0.39 ENST00000457035.1
ENST00000545696.1
ATG4A
autophagy related 4A, cysteine peptidase
chrX_+_107334895 0.39 ENST00000372232.3
ENST00000345734.3
ENST00000372254.3
ATG4A
autophagy related 4A, cysteine peptidase
chr5_-_122759032 0.38 ENST00000510582.3
ENST00000328236.5
ENST00000306481.6
ENST00000508442.2
ENST00000395431.2
CEP120
centrosomal protein 120kDa
chr5_-_1801408 0.37 ENST00000505818.1
MRPL36
mitochondrial ribosomal protein L36
chr8_+_132952112 0.37 ENST00000520362.1
ENST00000519656.1
EFR3A
EFR3 homolog A (S. cerevisiae)
chr3_+_63953415 0.37 ENST00000484332.1
ATXN7
ataxin 7
chr8_+_26150628 0.37 ENST00000523925.1
ENST00000315985.7
PPP2R2A
protein phosphatase 2, regulatory subunit B, alpha
chr16_+_21623958 0.36 ENST00000568826.1
METTL9
methyltransferase like 9
chr2_+_157330081 0.36 ENST00000409674.1
GPD2
glycerol-3-phosphate dehydrogenase 2 (mitochondrial)
chr7_+_151038850 0.36 ENST00000355851.4
ENST00000566856.1
ENST00000470229.1
NUB1
negative regulator of ubiquitin-like proteins 1
chr6_-_134639180 0.35 ENST00000367858.5
SGK1
serum/glucocorticoid regulated kinase 1
chr3_+_130569592 0.34 ENST00000533801.2
ATP2C1
ATPase, Ca++ transporting, type 2C, member 1
chr11_-_130786400 0.34 ENST00000265909.4
SNX19
sorting nexin 19
chr7_+_107224364 0.33 ENST00000491150.1
BCAP29
B-cell receptor-associated protein 29
chr9_+_71944241 0.33 ENST00000257515.8
FAM189A2
family with sequence similarity 189, member A2
chr4_-_23735183 0.33 ENST00000507666.1
RP11-380P13.2
RP11-380P13.2
chr6_+_158733692 0.32 ENST00000367094.2
ENST00000367097.3
TULP4
tubby like protein 4
chr7_+_116451100 0.32 ENST00000464223.1
ENST00000484325.1
CAPZA2
capping protein (actin filament) muscle Z-line, alpha 2
chr10_+_96522361 0.31 ENST00000371321.3
CYP2C19
cytochrome P450, family 2, subfamily C, polypeptide 19
chr4_-_70725856 0.31 ENST00000226444.3
SULT1E1
sulfotransferase family 1E, estrogen-preferring, member 1
chr2_+_68961934 0.31 ENST00000409202.3
ARHGAP25
Rho GTPase activating protein 25
chr18_+_21719018 0.31 ENST00000585037.1
ENST00000415309.2
ENST00000399481.2
ENST00000577705.1
ENST00000327201.6
CABYR
calcium binding tyrosine-(Y)-phosphorylation regulated
chr1_-_86848760 0.31 ENST00000460698.2
ODF2L
outer dense fiber of sperm tails 2-like
chr3_+_130569429 0.31 ENST00000505330.1
ENST00000504381.1
ENST00000507488.2
ENST00000393221.4
ATP2C1
ATPase, Ca++ transporting, type 2C, member 1
chr20_+_52105495 0.31 ENST00000439873.2
AL354993.1
Cell growth-inhibiting protein 7; HCG1784586; Uncharacterized protein
chr9_+_82188077 0.30 ENST00000425506.1
TLE4
transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
chr3_+_43328004 0.30 ENST00000454177.1
ENST00000429705.2
ENST00000296088.7
ENST00000437827.1
SNRK
SNF related kinase
chr17_+_29664830 0.30 ENST00000444181.2
ENST00000417592.2
NF1
neurofibromin 1
chr4_+_166300084 0.30 ENST00000402744.4
CPE
carboxypeptidase E
chr12_+_133195356 0.30 ENST00000389110.3
ENST00000449132.2
ENST00000343948.4
ENST00000352418.4
ENST00000350048.5
ENST00000351222.4
ENST00000348800.5
ENST00000542301.1
ENST00000536121.1
P2RX2
purinergic receptor P2X, ligand-gated ion channel, 2
chr5_-_64064508 0.29 ENST00000513458.4
SREK1IP1
SREK1-interacting protein 1
chr6_-_88299678 0.29 ENST00000369536.5
RARS2
arginyl-tRNA synthetase 2, mitochondrial
chr2_-_207082748 0.29 ENST00000407325.2
ENST00000411719.1
GPR1
G protein-coupled receptor 1
chr2_+_68961905 0.29 ENST00000295381.3
ARHGAP25
Rho GTPase activating protein 25
chr2_+_68962014 0.29 ENST00000467265.1
ARHGAP25
Rho GTPase activating protein 25
chr18_+_21718924 0.29 ENST00000399496.3
CABYR
calcium binding tyrosine-(Y)-phosphorylation regulated
chr6_-_36515177 0.28 ENST00000229812.7
STK38
serine/threonine kinase 38
chr13_+_102142296 0.28 ENST00000376162.3
ITGBL1
integrin, beta-like 1 (with EGF-like repeat domains)
chr8_-_18666360 0.28 ENST00000286485.8
PSD3
pleckstrin and Sec7 domain containing 3

Network of associatons between targets according to the STRING database.

First level regulatory network of HOXD10

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.1 GO:0050717 positive regulation of interleukin-1 alpha secretion(GO:0050717)
0.5 2.5 GO:1903285 negative regulation of dopamine uptake involved in synaptic transmission(GO:0051585) norepinephrine uptake(GO:0051620) regulation of norepinephrine uptake(GO:0051621) negative regulation of norepinephrine uptake(GO:0051622) negative regulation of catecholamine uptake involved in synaptic transmission(GO:0051945) regulation of glutathione peroxidase activity(GO:1903282) positive regulation of glutathione peroxidase activity(GO:1903284) positive regulation of hydrogen peroxide catabolic process(GO:1903285) positive regulation of peroxidase activity(GO:2000470)
0.5 1.5 GO:0070175 positive regulation of enamel mineralization(GO:0070175)
0.5 1.9 GO:0001808 negative regulation of type IV hypersensitivity(GO:0001808)
0.5 1.4 GO:0032289 central nervous system myelin formation(GO:0032289)
0.4 2.2 GO:0090362 positive regulation of platelet-derived growth factor production(GO:0090362)
0.4 1.7 GO:1905205 positive regulation of connective tissue replacement(GO:1905205)
0.4 3.9 GO:0038044 transforming growth factor-beta secretion(GO:0038044)
0.3 0.9 GO:1903674 regulation of cap-dependent translational initiation(GO:1903674) positive regulation of cap-dependent translational initiation(GO:1903676)
0.3 1.1 GO:0035188 blastocyst hatching(GO:0001835) hatching(GO:0035188) organism emergence from protective structure(GO:0071684)
0.2 1.0 GO:0035425 autocrine signaling(GO:0035425)
0.2 1.4 GO:0002225 positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antimicrobial humoral response(GO:0002760) positive regulation of antibacterial peptide production(GO:0002803)
0.2 0.8 GO:1990502 dense core granule maturation(GO:1990502)
0.2 0.6 GO:0001798 positive regulation of type IIa hypersensitivity(GO:0001798) positive regulation of type II hypersensitivity(GO:0002894)
0.2 1.6 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.2 0.9 GO:0030807 positive regulation of cyclic nucleotide catabolic process(GO:0030807) positive regulation of cAMP catabolic process(GO:0030822) positive regulation of purine nucleotide catabolic process(GO:0033123)
0.2 0.9 GO:2000638 regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
0.2 1.6 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.2 0.7 GO:2000097 regulation of smooth muscle cell-matrix adhesion(GO:2000097)
0.2 1.5 GO:1903265 positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
0.2 0.5 GO:0002514 B cell tolerance induction(GO:0002514) regulation of B cell tolerance induction(GO:0002661) positive regulation of B cell tolerance induction(GO:0002663)
0.2 0.5 GO:1903371 establishment of protein localization to endoplasmic reticulum membrane(GO:0097051) regulation of endoplasmic reticulum tubular network organization(GO:1903371)
0.1 0.8 GO:0051697 protein delipidation(GO:0051697)
0.1 1.1 GO:0071896 protein localization to adherens junction(GO:0071896)
0.1 0.8 GO:1904381 Golgi apparatus mannose trimming(GO:1904381)
0.1 1.0 GO:0000023 maltose metabolic process(GO:0000023)
0.1 0.4 GO:0032053 ciliary basal body organization(GO:0032053)
0.1 0.3 GO:0006711 estrogen catabolic process(GO:0006711)
0.1 0.3 GO:0061534 gamma-aminobutyric acid secretion, neurotransmission(GO:0061534)
0.1 0.3 GO:0030070 insulin processing(GO:0030070)
0.1 0.9 GO:0003383 apical constriction(GO:0003383)
0.1 0.7 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
0.1 0.6 GO:0007060 male meiosis chromosome segregation(GO:0007060)
0.1 0.5 GO:0014004 microglia differentiation(GO:0014004) microglia development(GO:0014005) cellular response to norepinephrine stimulus(GO:0071874)
0.1 0.5 GO:1900827 maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.1 0.6 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.1 0.2 GO:0019516 lactate oxidation(GO:0019516)
0.1 0.2 GO:0042040 molybdenum incorporation into molybdenum-molybdopterin complex(GO:0018315) metal incorporation into metallo-molybdopterin complex(GO:0042040) glycine receptor clustering(GO:0072579)
0.1 0.6 GO:1990481 mRNA pseudouridine synthesis(GO:1990481)
0.1 1.1 GO:0019885 antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.1 0.5 GO:0090063 positive regulation of microtubule nucleation(GO:0090063)
0.1 0.9 GO:2000623 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.1 0.6 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.1 0.2 GO:0048007 antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003) antigen processing and presentation, exogenous lipid antigen via MHC class Ib(GO:0048007)
0.1 1.3 GO:1901748 leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750)
0.1 0.4 GO:0006127 glycerophosphate shuttle(GO:0006127)
0.1 0.4 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.1 0.8 GO:0021759 globus pallidus development(GO:0021759)
0.1 0.8 GO:0033299 secretion of lysosomal enzymes(GO:0033299)
0.1 2.3 GO:0042481 regulation of odontogenesis(GO:0042481)
0.1 5.3 GO:0007585 respiratory gaseous exchange(GO:0007585)
0.1 0.6 GO:0043950 positive regulation of cAMP-mediated signaling(GO:0043950)
0.1 2.7 GO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.1 0.2 GO:0072616 interleukin-18 secretion(GO:0072616)
0.1 0.4 GO:0046952 ketone body catabolic process(GO:0046952)
0.0 0.2 GO:0046338 phosphatidylethanolamine catabolic process(GO:0046338)
0.0 1.2 GO:0072540 T-helper 17 cell lineage commitment(GO:0072540)
0.0 0.4 GO:0040032 post-embryonic body morphogenesis(GO:0040032)
0.0 0.3 GO:0016098 monoterpenoid metabolic process(GO:0016098)
0.0 0.7 GO:0051451 myoblast migration(GO:0051451)
0.0 0.6 GO:0006228 UTP biosynthetic process(GO:0006228)
0.0 0.5 GO:0009744 response to sucrose(GO:0009744) response to disaccharide(GO:0034285)
0.0 0.4 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.0 0.2 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.0 0.7 GO:0090435 protein localization to nuclear envelope(GO:0090435)
0.0 0.5 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.0 0.4 GO:2000582 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.0 0.3 GO:0032497 detection of lipopolysaccharide(GO:0032497)
0.0 0.4 GO:0044821 meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
0.0 0.9 GO:0051639 actin filament network formation(GO:0051639)
0.0 0.6 GO:0048341 paraxial mesoderm formation(GO:0048341)
0.0 1.5 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.0 0.6 GO:0014877 response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.0 0.4 GO:0034378 chylomicron assembly(GO:0034378)
0.0 0.4 GO:1901409 positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.0 0.5 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.0 0.3 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.0 0.1 GO:0006543 glutamine catabolic process(GO:0006543)
0.0 0.5 GO:0046085 adenosine metabolic process(GO:0046085)
0.0 2.1 GO:0018149 peptide cross-linking(GO:0018149)
0.0 0.3 GO:0070294 renal sodium ion transport(GO:0003096) renal sodium ion absorption(GO:0070294)
0.0 0.7 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.0 0.1 GO:0042214 terpene metabolic process(GO:0042214)
0.0 0.5 GO:0060348 bone development(GO:0060348)
0.0 1.6 GO:0045824 negative regulation of innate immune response(GO:0045824)
0.0 0.1 GO:0060152 peroxisome localization(GO:0060151) microtubule-based peroxisome localization(GO:0060152)
0.0 0.1 GO:0002318 myeloid progenitor cell differentiation(GO:0002318)
0.0 0.8 GO:0030033 microvillus assembly(GO:0030033)
0.0 0.4 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.0 0.2 GO:0071802 negative regulation of podosome assembly(GO:0071802)
0.0 0.4 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839)
0.0 0.2 GO:1990504 dense core granule exocytosis(GO:1990504)
0.0 0.2 GO:0097056 selenocysteinyl-tRNA(Sec) biosynthetic process(GO:0097056)
0.0 0.4 GO:2000675 negative regulation of type B pancreatic cell apoptotic process(GO:2000675)
0.0 0.1 GO:0035038 female pronucleus assembly(GO:0035038)
0.0 0.1 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.0 0.3 GO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)
0.0 0.2 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.0 6.3 GO:0030216 keratinocyte differentiation(GO:0030216)
0.0 0.3 GO:0030432 peristalsis(GO:0030432)
0.0 0.1 GO:0019918 peptidyl-arginine methylation, to symmetrical-dimethyl arginine(GO:0019918)
0.0 0.6 GO:0003351 epithelial cilium movement(GO:0003351)
0.0 0.2 GO:0035754 B cell chemotaxis(GO:0035754)
0.0 0.2 GO:0031987 locomotion involved in locomotory behavior(GO:0031987)
0.0 0.2 GO:0035095 behavioral response to nicotine(GO:0035095)
0.0 0.1 GO:0061484 hematopoietic stem cell homeostasis(GO:0061484)
0.0 0.4 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
0.0 0.2 GO:0002329 pre-B cell differentiation(GO:0002329)
0.0 0.6 GO:0045898 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.0 0.4 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.0 0.1 GO:0046598 positive regulation of viral entry into host cell(GO:0046598)
0.0 0.2 GO:1903599 positive regulation of mitophagy(GO:1903599)
0.0 0.5 GO:0046596 regulation of viral entry into host cell(GO:0046596)
0.0 0.2 GO:1904776 regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.0 0.4 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.0 0.1 GO:0085032 modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032)
0.0 0.7 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 0.1 GO:0060005 vestibular reflex(GO:0060005)
0.0 0.1 GO:1904425 negative regulation of GTP binding(GO:1904425)
0.0 0.3 GO:0031629 synaptic vesicle fusion to presynaptic active zone membrane(GO:0031629) vesicle fusion to plasma membrane(GO:0099500)
0.0 0.1 GO:0035494 SNARE complex disassembly(GO:0035494)
0.0 0.1 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.0 1.1 GO:0021762 substantia nigra development(GO:0021762)
0.0 0.2 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.0 0.0 GO:0009236 cobalamin biosynthetic process(GO:0009236)
0.0 0.1 GO:0033625 positive regulation of integrin activation(GO:0033625)
0.0 1.2 GO:0032755 positive regulation of interleukin-6 production(GO:0032755)
0.0 1.2 GO:0000245 spliceosomal complex assembly(GO:0000245)
0.0 0.2 GO:0031532 actin cytoskeleton reorganization(GO:0031532)
0.0 0.1 GO:1903546 protein localization to photoreceptor outer segment(GO:1903546)
0.0 0.2 GO:0042359 vitamin D metabolic process(GO:0042359)
0.0 0.3 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 3.9 GO:0034685 integrin alphav-beta6 complex(GO:0034685)
0.4 3.4 GO:0097169 AIM2 inflammasome complex(GO:0097169)
0.3 1.7 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.2 1.4 GO:0097209 epidermal lamellar body(GO:0097209)
0.2 1.9 GO:0005955 calcineurin complex(GO:0005955)
0.1 0.9 GO:0089701 U2AF(GO:0089701)
0.1 0.9 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.1 9.2 GO:0001533 cornified envelope(GO:0001533)
0.1 0.9 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.1 0.4 GO:0031592 centrosomal corona(GO:0031592)
0.1 1.3 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.1 2.5 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.1 0.6 GO:0032584 growth cone membrane(GO:0032584)
0.1 0.4 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0 0.5 GO:1990812 growth cone filopodium(GO:1990812)
0.0 0.5 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.0 0.6 GO:0030478 actin cap(GO:0030478)
0.0 0.9 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 0.5 GO:0035686 sperm fibrous sheath(GO:0035686)
0.0 0.2 GO:1990037 Lewy body core(GO:1990037)
0.0 1.4 GO:0030904 retromer complex(GO:0030904)
0.0 0.9 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.5 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.0 1.5 GO:0005605 basal lamina(GO:0005605)
0.0 0.8 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 1.0 GO:0016580 Sin3 complex(GO:0016580)
0.0 0.6 GO:0070938 contractile ring(GO:0070938)
0.0 1.8 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.0 0.3 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.0 0.3 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.0 0.4 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.0 0.2 GO:0070695 FHF complex(GO:0070695)
0.0 0.4 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.7 GO:0005639 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.0 0.5 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 2.3 GO:0101003 ficolin-1-rich granule membrane(GO:0101003)
0.0 0.1 GO:0000333 telomerase catalytic core complex(GO:0000333)
0.0 0.5 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 0.2 GO:0008091 spectrin(GO:0008091)
0.0 0.3 GO:0008290 F-actin capping protein complex(GO:0008290)
0.0 0.2 GO:0030123 AP-3 adaptor complex(GO:0030123)
0.0 0.4 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 1.9 GO:0005776 autophagosome(GO:0005776)
0.0 0.5 GO:0000178 exosome (RNase complex)(GO:0000178)
0.0 0.5 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.0 1.6 GO:0035578 azurophil granule lumen(GO:0035578)
0.0 0.3 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.2 GO:0012505 endomembrane system(GO:0012505)
0.0 0.5 GO:0034364 high-density lipoprotein particle(GO:0034364)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.5 GO:0060961 phospholipase D inhibitor activity(GO:0060961)
0.3 1.9 GO:0042015 interleukin-20 binding(GO:0042015)
0.2 0.9 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
0.2 0.7 GO:1990175 EH domain binding(GO:1990175)
0.2 0.5 GO:0050146 nucleoside phosphotransferase activity(GO:0050146)
0.1 0.6 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.1 3.6 GO:0050700 CARD domain binding(GO:0050700)
0.1 0.4 GO:0017130 poly(C) RNA binding(GO:0017130)
0.1 1.9 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.1 0.5 GO:0005026 transforming growth factor beta receptor activity, type II(GO:0005026)
0.1 0.5 GO:0004948 calcitonin receptor activity(GO:0004948)
0.1 0.9 GO:0050816 phosphothreonine binding(GO:0050816)
0.1 1.0 GO:0004558 alpha-1,4-glucosidase activity(GO:0004558) maltose alpha-glucosidase activity(GO:0032450)
0.1 0.4 GO:0008260 3-oxoacid CoA-transferase activity(GO:0008260)
0.1 0.9 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.1 0.4 GO:0052590 sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity(GO:0052590) sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity(GO:0052591)
0.1 0.2 GO:0061599 molybdopterin adenylyltransferase activity(GO:0061598) molybdopterin molybdotransferase activity(GO:0061599)
0.1 0.8 GO:0004111 creatine kinase activity(GO:0004111)
0.1 2.7 GO:0003746 translation elongation factor activity(GO:0003746)
0.1 1.3 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.1 0.4 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.1 0.2 GO:1902271 D3 vitamins binding(GO:1902271)
0.1 1.0 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.1 1.1 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.1 0.8 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.1 0.3 GO:0050815 phosphoserine binding(GO:0050815)
0.0 1.9 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 0.3 GO:0047894 flavonol 3-sulfotransferase activity(GO:0047894)
0.0 0.3 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.0 0.8 GO:0005537 mannose binding(GO:0005537)
0.0 1.3 GO:0002162 dystroglycan binding(GO:0002162)
0.0 1.1 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 4.8 GO:0001618 virus receptor activity(GO:0001618)
0.0 0.4 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.0 1.3 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.6 GO:0019870 potassium channel inhibitor activity(GO:0019870)
0.0 0.3 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.0 0.5 GO:0005221 intracellular cyclic nucleotide activated cation channel activity(GO:0005221) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.0 0.2 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.0 0.8 GO:0044213 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.0 0.5 GO:0051425 PTB domain binding(GO:0051425)
0.0 1.7 GO:0030332 cyclin binding(GO:0030332)
0.0 0.1 GO:0008511 sodium:potassium:chloride symporter activity(GO:0008511)
0.0 0.5 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.0 0.4 GO:0051430 corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.0 0.6 GO:0008494 translation activator activity(GO:0008494)
0.0 0.6 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 4.1 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.7 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.7 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 1.1 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.0 0.3 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.0 0.1 GO:1901375 acetylcholine transmembrane transporter activity(GO:0005277) secondary active organic cation transmembrane transporter activity(GO:0008513) acetate ester transmembrane transporter activity(GO:1901375)
0.0 0.2 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.0 0.6 GO:0008392 arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392)
0.0 6.9 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.4 GO:0048156 tau protein binding(GO:0048156)
0.0 1.0 GO:0015248 sterol transporter activity(GO:0015248)
0.0 1.9 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.1 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.0 0.6 GO:0017166 vinculin binding(GO:0017166)
0.0 0.1 GO:0035243 protein-arginine omega-N symmetric methyltransferase activity(GO:0035243)
0.0 0.1 GO:0005477 pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.0 0.4 GO:0045504 dynein heavy chain binding(GO:0045504)
0.0 0.6 GO:0017160 Ral GTPase binding(GO:0017160)
0.0 0.6 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.9 GO:0042056 chemoattractant activity(GO:0042056)
0.0 0.7 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.2 GO:0042731 PH domain binding(GO:0042731)
0.0 0.6 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.0 0.7 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.9 GO:0015485 cholesterol binding(GO:0015485)
0.0 1.0 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 0.6 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.0 0.9 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.1 GO:0004359 glutaminase activity(GO:0004359)
0.0 0.5 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0 0.5 GO:0030275 LRR domain binding(GO:0030275)
0.0 0.2 GO:0097016 L27 domain binding(GO:0097016)
0.0 0.3 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0 0.5 GO:0070840 dynein complex binding(GO:0070840)
0.0 0.0 GO:1904854 proteasome core complex binding(GO:1904854)
0.0 0.0 GO:0016503 pheromone receptor activity(GO:0016503)
0.0 0.3 GO:0017081 chloride channel regulator activity(GO:0017081)
0.0 0.4 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.2 GO:0001972 retinoic acid binding(GO:0001972)
0.0 0.3 GO:0031210 phosphatidylcholine binding(GO:0031210)
0.0 1.0 GO:0004407 histone deacetylase activity(GO:0004407)
0.0 0.6 GO:0036002 pre-mRNA binding(GO:0036002)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.9 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.1 1.3 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.1 2.1 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 1.8 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 2.4 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 0.9 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 0.6 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 1.5 PID MYC PATHWAY C-MYC pathway
0.0 0.9 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 1.7 PID EPHB FWD PATHWAY EPHB forward signaling
0.0 0.4 PID ARF 3PATHWAY Arf1 pathway
0.0 0.9 PID BARD1 PATHWAY BARD1 signaling events
0.0 0.4 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 1.8 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 4.3 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.5 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.0 0.6 PID CXCR3 PATHWAY CXCR3-mediated signaling events
0.0 0.9 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 1.2 PID CASPASE PATHWAY Caspase cascade in apoptosis

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.5 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.1 2.6 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.1 1.1 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.0 1.5 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 0.5 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 0.6 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.0 0.6 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
0.0 1.5 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.0 0.3 REACTOME TRAF6 MEDIATED INDUCTION OF TAK1 COMPLEX Genes involved in TRAF6 mediated induction of TAK1 complex
0.0 0.5 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.0 1.2 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 0.9 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 0.5 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 1.8 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 0.9 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.0 0.8 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.0 0.9 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 1.5 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 0.9 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 0.3 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 0.4 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 1.6 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 0.8 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 1.0 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.0 0.4 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 0.3 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.0 0.6 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 0.4 REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR Genes involved in Prostacyclin signalling through prostacyclin receptor
0.0 0.2 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle