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SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for HOXD4

Z-value: 0.46

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Transcription factors associated with HOXD4

Gene Symbol Gene ID Gene Info
HOXD4
ENSG00000170166.5 homeobox D4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HOXD4hg19_v2_chr2_+_177015950_1770159500.811.6e-05Click!

Activity profile of HOXD4 motif

Sorted Z-values of HOXD4 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr4_+_155484155 2.28 ENST00000509493.1
FGB
fibrinogen beta chain
chr4_+_155484103 2.25 ENST00000302068.4
FGB
fibrinogen beta chain
chr1_-_238108575 2.09 ENST00000604646.1
MTRNR2L11
MT-RNR2-like 11 (pseudogene)
chr17_-_64225508 1.68 ENST00000205948.6
APOH
apolipoprotein H (beta-2-glycoprotein I)
chr15_-_88799661 1.61 ENST00000360948.2
ENST00000357724.2
ENST00000355254.2
ENST00000317501.3
NTRK3
neurotrophic tyrosine kinase, receptor, type 3
chr1_+_186798073 1.41 ENST00000367466.3
ENST00000442353.2
PLA2G4A
phospholipase A2, group IVA (cytosolic, calcium-dependent)
chr19_+_48828788 1.02 ENST00000594198.1
ENST00000597279.1
ENST00000593437.1
EMP3
epithelial membrane protein 3
chr2_-_165424973 0.96 ENST00000543549.1
GRB14
growth factor receptor-bound protein 14
chr17_-_78450398 0.92 ENST00000306773.4
NPTX1
neuronal pentraxin I
chr19_+_48828582 0.89 ENST00000270221.6
ENST00000596315.1
EMP3
epithelial membrane protein 3
chr22_-_29107919 0.70 ENST00000434810.1
ENST00000456369.1
CHEK2
checkpoint kinase 2
chr3_+_159943362 0.70 ENST00000326474.3
C3orf80
chromosome 3 open reading frame 80
chr1_+_42846443 0.67 ENST00000410070.2
ENST00000431473.3
RIMKLA
ribosomal modification protein rimK-like family member A
chr4_-_89442940 0.66 ENST00000527353.1
PIGY
phosphatidylinositol glycan anchor biosynthesis, class Y
chr3_-_149095652 0.64 ENST00000305366.3
TM4SF1
transmembrane 4 L six family member 1
chr8_-_40200877 0.63 ENST00000521030.1
CTA-392C11.1
CTA-392C11.1
chr7_-_77427676 0.63 ENST00000257663.3
TMEM60
transmembrane protein 60
chr3_-_137851220 0.63 ENST00000236709.3
A4GNT
alpha-1,4-N-acetylglucosaminyltransferase
chr16_-_29910853 0.57 ENST00000308713.5
SEZ6L2
seizure related 6 homolog (mouse)-like 2
chr4_-_105416039 0.57 ENST00000394767.2
CXXC4
CXXC finger protein 4
chr12_-_112279694 0.56 ENST00000443596.1
ENST00000442119.1
MAPKAPK5-AS1
MAPKAPK5 antisense RNA 1
chr6_-_76072719 0.56 ENST00000370020.1
FILIP1
filamin A interacting protein 1
chr16_+_87636474 0.56 ENST00000284262.2
JPH3
junctophilin 3
chr11_-_31531121 0.55 ENST00000532287.1
ENST00000526776.1
ENST00000534812.1
ENST00000529749.1
ENST00000278200.1
ENST00000530023.1
ENST00000533642.1
IMMP1L
IMP1 inner mitochondrial membrane peptidase-like (S. cerevisiae)
chr15_-_64386120 0.54 ENST00000300030.3
FAM96A
family with sequence similarity 96, member A
chrX_-_10645773 0.53 ENST00000453318.2
MID1
midline 1 (Opitz/BBB syndrome)
chr15_-_54025300 0.52 ENST00000559418.1
WDR72
WD repeat domain 72
chr1_-_231560790 0.50 ENST00000366641.3
EGLN1
egl-9 family hypoxia-inducible factor 1
chr14_-_54425475 0.50 ENST00000559642.1
BMP4
bone morphogenetic protein 4
chr18_+_68002675 0.49 ENST00000584919.1
RP11-41O4.1
Uncharacterized protein
chr15_-_56209306 0.49 ENST00000506154.1
ENST00000338963.2
ENST00000508342.1
NEDD4
neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase
chr2_+_234826016 0.48 ENST00000324695.4
ENST00000433712.2
TRPM8
transient receptor potential cation channel, subfamily M, member 8
chr2_+_176981307 0.47 ENST00000249501.4
HOXD10
homeobox D10
chr14_+_61449076 0.46 ENST00000526105.1
SLC38A6
solute carrier family 38, member 6
chr15_-_64385981 0.45 ENST00000557835.1
ENST00000380290.3
ENST00000559950.1
FAM96A
family with sequence similarity 96, member A
chr5_-_179499108 0.44 ENST00000521389.1
RNF130
ring finger protein 130
chr8_-_102803163 0.44 ENST00000523645.1
ENST00000520346.1
ENST00000220931.6
ENST00000522448.1
ENST00000522951.1
ENST00000522252.1
ENST00000519098.1
NCALD
neurocalcin delta
chr9_-_128246769 0.44 ENST00000444226.1
MAPKAP1
mitogen-activated protein kinase associated protein 1
chr19_+_50016610 0.44 ENST00000596975.1
FCGRT
Fc fragment of IgG, receptor, transporter, alpha
chr10_+_48189612 0.43 ENST00000453919.1
AGAP9
ArfGAP with GTPase domain, ankyrin repeat and PH domain 9
chr1_+_159750776 0.43 ENST00000368107.1
DUSP23
dual specificity phosphatase 23
chrX_+_70752917 0.41 ENST00000373719.3
OGT
O-linked N-acetylglucosamine (GlcNAc) transferase
chr11_-_77790865 0.40 ENST00000534029.1
ENST00000525085.1
ENST00000527806.1
ENST00000528164.1
ENST00000528251.1
ENST00000530054.1
NDUFC2
NDUFC2-KCTD14
NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 2, 14.5kDa
NDUFC2-KCTD14 readthrough
chr3_+_158787041 0.39 ENST00000471575.1
ENST00000476809.1
ENST00000485419.1
IQCJ-SCHIP1
IQCJ-SCHIP1 readthrough
chr12_+_21168630 0.39 ENST00000421593.2
SLCO1B7
solute carrier organic anion transporter family, member 1B7 (non-functional)
chr1_-_235814048 0.38 ENST00000450593.1
ENST00000366598.4
GNG4
guanine nucleotide binding protein (G protein), gamma 4
chr2_-_176046391 0.38 ENST00000392541.3
ENST00000409194.1
ATP5G3
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C3 (subunit 9)
chr14_+_23067146 0.37 ENST00000428304.2
ABHD4
abhydrolase domain containing 4
chr2_+_234590556 0.37 ENST00000373426.3
UGT1A7
UDP glucuronosyltransferase 1 family, polypeptide A7
chr3_+_142342228 0.36 ENST00000337777.3
PLS1
plastin 1
chr3_+_173116225 0.34 ENST00000457714.1
NLGN1
neuroligin 1
chr5_-_179499086 0.33 ENST00000261947.4
RNF130
ring finger protein 130
chr17_-_26733179 0.33 ENST00000440501.1
ENST00000321666.5
SLC46A1
solute carrier family 46 (folate transporter), member 1
chrX_-_110655306 0.32 ENST00000371993.2
DCX
doublecortin
chr16_+_84801852 0.32 ENST00000569925.1
ENST00000567526.1
USP10
ubiquitin specific peptidase 10
chr19_-_5903714 0.31 ENST00000586349.1
ENST00000585661.1
ENST00000308961.4
ENST00000592634.1
ENST00000418389.2
ENST00000252675.5
AC024592.12
NDUFA11
FUT5
Uncharacterized protein
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 11, 14.7kDa
fucosyltransferase 5 (alpha (1,3) fucosyltransferase)
chr11_-_64684672 0.31 ENST00000377264.3
ENST00000421419.2
ATG2A
autophagy related 2A
chr1_-_101360331 0.31 ENST00000416479.1
ENST00000370113.3
EXTL2
exostosin-like glycosyltransferase 2
chr3_-_178103144 0.30 ENST00000417383.1
ENST00000418585.1
ENST00000411727.1
ENST00000439810.1
RP11-33A14.1
RP11-33A14.1
chr16_+_103816 0.29 ENST00000383018.3
ENST00000417493.1
SNRNP25
small nuclear ribonucleoprotein 25kDa (U11/U12)
chr22_-_30642728 0.29 ENST00000403987.3
LIF
leukemia inhibitory factor
chr9_+_97562440 0.29 ENST00000395357.2
C9orf3
chromosome 9 open reading frame 3
chr22_+_23248512 0.28 ENST00000390325.2
IGLC3
immunoglobulin lambda constant 3 (Kern-Oz+ marker)
chr10_+_95848824 0.28 ENST00000371385.3
ENST00000371375.1
PLCE1
phospholipase C, epsilon 1
chr2_+_179317994 0.28 ENST00000375129.4
DFNB59
deafness, autosomal recessive 59
chr7_-_121944491 0.28 ENST00000331178.4
ENST00000427185.2
ENST00000442488.2
FEZF1
FEZ family zinc finger 1
chr18_+_32556892 0.28 ENST00000591734.1
ENST00000413393.1
ENST00000589180.1
ENST00000587359.1
MAPRE2
microtubule-associated protein, RP/EB family, member 2
chr2_-_99279928 0.27 ENST00000414521.2
MGAT4A
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A
chr3_+_69812877 0.27 ENST00000457080.1
ENST00000328528.6
MITF
microphthalmia-associated transcription factor
chr18_-_19283649 0.26 ENST00000584464.1
ENST00000578270.1
ABHD3
abhydrolase domain containing 3
chr12_+_41831485 0.26 ENST00000539469.2
ENST00000298919.7
PDZRN4
PDZ domain containing ring finger 4
chr6_-_49712147 0.26 ENST00000433368.2
ENST00000354620.4
CRISP3
cysteine-rich secretory protein 3
chr2_+_90198535 0.26 ENST00000390276.2
IGKV1D-12
immunoglobulin kappa variable 1D-12
chr12_+_9066472 0.26 ENST00000538657.1
PHC1
polyhomeotic homolog 1 (Drosophila)
chr22_+_44427230 0.25 ENST00000444029.1
PARVB
parvin, beta
chr2_+_179318295 0.25 ENST00000442710.1
DFNB59
deafness, autosomal recessive 59
chr3_-_149293990 0.25 ENST00000472417.1
WWTR1
WW domain containing transcription regulator 1
chr7_-_137028534 0.24 ENST00000348225.2
PTN
pleiotrophin
chr3_-_11623804 0.24 ENST00000451674.2
VGLL4
vestigial like 4 (Drosophila)
chr9_-_131790550 0.24 ENST00000372554.4
ENST00000372564.3
SH3GLB2
SH3-domain GRB2-like endophilin B2
chr1_+_87380299 0.23 ENST00000370551.4
ENST00000370550.5
HS2ST1
heparan sulfate 2-O-sulfotransferase 1
chr3_-_186524144 0.23 ENST00000427785.1
RFC4
replication factor C (activator 1) 4, 37kDa
chr17_-_29624343 0.23 ENST00000247271.4
OMG
oligodendrocyte myelin glycoprotein
chr17_-_7218631 0.23 ENST00000577040.2
ENST00000389167.5
ENST00000391950.3
GPS2
G protein pathway suppressor 2
chr14_-_101036119 0.23 ENST00000355173.2
BEGAIN
brain-enriched guanylate kinase-associated
chr6_-_15548591 0.23 ENST00000509674.1
DTNBP1
dystrobrevin binding protein 1
chr4_+_183065793 0.22 ENST00000512480.1
TENM3
teneurin transmembrane protein 3
chr2_-_99871570 0.22 ENST00000333017.2
ENST00000409679.1
ENST00000423306.1
LYG2
lysozyme G-like 2
chr1_+_170115142 0.22 ENST00000439373.2
METTL11B
methyltransferase like 11B
chr21_+_43823983 0.22 ENST00000291535.6
ENST00000450356.1
ENST00000319294.6
ENST00000398367.1
UBASH3A
ubiquitin associated and SH3 domain containing A
chr7_-_137028498 0.22 ENST00000393083.2
PTN
pleiotrophin
chr3_-_191000172 0.22 ENST00000427544.2
UTS2B
urotensin 2B
chr2_+_190541153 0.22 ENST00000313581.4
ENST00000438402.2
ENST00000431575.2
ENST00000281412.6
ANKAR
ankyrin and armadillo repeat containing
chr6_+_123317116 0.22 ENST00000275162.5
CLVS2
clavesin 2
chr15_-_94614049 0.22 ENST00000556447.1
ENST00000555772.1
CTD-3049M7.1
CTD-3049M7.1
chr14_+_23067166 0.21 ENST00000216327.6
ENST00000542041.1
ABHD4
abhydrolase domain containing 4
chr14_+_78174414 0.21 ENST00000557342.1
ENST00000238688.5
ENST00000557623.1
ENST00000557431.1
ENST00000556831.1
ENST00000556375.1
ENST00000553981.1
SLIRP
SRA stem-loop interacting RNA binding protein
chr2_-_175462456 0.21 ENST00000409891.1
ENST00000410117.1
WIPF1
WAS/WASL interacting protein family, member 1
chr14_-_24911868 0.20 ENST00000554698.1
SDR39U1
short chain dehydrogenase/reductase family 39U, member 1
chr4_+_71019903 0.20 ENST00000344526.5
C4orf40
chromosome 4 open reading frame 40
chr3_+_140981456 0.20 ENST00000504264.1
ACPL2
acid phosphatase-like 2
chr1_+_109265033 0.20 ENST00000445274.1
FNDC7
fibronectin type III domain containing 7
chr14_-_24911971 0.20 ENST00000555365.1
ENST00000399395.3
SDR39U1
short chain dehydrogenase/reductase family 39U, member 1
chr3_+_178276488 0.19 ENST00000432997.1
ENST00000455865.1
KCNMB2
potassium large conductance calcium-activated channel, subfamily M, beta member 2
chr17_+_59489112 0.19 ENST00000335108.2
C17orf82
chromosome 17 open reading frame 82
chr3_-_4927447 0.19 ENST00000449914.1
AC018816.3
Uncharacterized protein
chr4_+_124571409 0.19 ENST00000514823.1
ENST00000511919.1
ENST00000508111.1
RP11-93L9.1
long intergenic non-protein coding RNA 1091
chr2_-_166060571 0.18 ENST00000360093.3
SCN3A
sodium channel, voltage-gated, type III, alpha subunit
chr11_-_36310958 0.18 ENST00000532705.1
ENST00000263401.5
ENST00000452374.2
COMMD9
COMM domain containing 9
chr18_+_22040593 0.18 ENST00000256906.4
HRH4
histamine receptor H4
chr5_+_52083730 0.18 ENST00000282588.6
ENST00000274311.2
ITGA1
PELO
integrin, alpha 1
pelota homolog (Drosophila)
chr4_-_130014609 0.18 ENST00000511426.1
SCLT1
sodium channel and clathrin linker 1
chr1_-_101360374 0.18 ENST00000535414.1
EXTL2
exostosin-like glycosyltransferase 2
chr20_+_5931497 0.17 ENST00000378886.2
ENST00000265187.4
MCM8
minichromosome maintenance complex component 8
chr2_-_228497888 0.17 ENST00000264387.4
ENST00000409066.1
C2orf83
chromosome 2 open reading frame 83
chr1_-_87379785 0.17 ENST00000401030.3
ENST00000370554.1
SEP15
Homo sapiens 15 kDa selenoprotein (SEP15), transcript variant 2, mRNA.
chr1_-_190446759 0.17 ENST00000367462.3
BRINP3
bone morphogenetic protein/retinoic acid inducible neural-specific 3
chr6_-_26250835 0.17 ENST00000446824.2
HIST1H3F
histone cluster 1, H3f
chr7_+_135611542 0.17 ENST00000416501.1
AC015987.2
AC015987.2
chrX_+_37850026 0.16 ENST00000341016.3
CXorf27
chromosome X open reading frame 27
chr2_-_166060552 0.16 ENST00000283254.7
ENST00000453007.1
SCN3A
sodium channel, voltage-gated, type III, alpha subunit
chr11_-_89224638 0.16 ENST00000535633.1
ENST00000263317.4
NOX4
NADPH oxidase 4
chr4_-_130014705 0.16 ENST00000503401.1
SCLT1
sodium channel and clathrin linker 1
chr9_+_130026756 0.16 ENST00000314904.5
ENST00000373387.4
GARNL3
GTPase activating Rap/RanGAP domain-like 3
chrX_+_77166172 0.15 ENST00000343533.5
ENST00000350425.4
ENST00000341514.6
ATP7A
ATPase, Cu++ transporting, alpha polypeptide
chr2_+_204801471 0.15 ENST00000316386.6
ENST00000435193.1
ICOS
inducible T-cell co-stimulator
chr9_-_93405352 0.15 ENST00000375765.3
DIRAS2
DIRAS family, GTP-binding RAS-like 2
chr2_-_163695128 0.15 ENST00000332142.5
KCNH7
potassium voltage-gated channel, subfamily H (eag-related), member 7
chr5_-_150727111 0.15 ENST00000335244.4
ENST00000521967.1
SLC36A2
solute carrier family 36 (proton/amino acid symporter), member 2
chr7_+_77428066 0.15 ENST00000422959.2
ENST00000307305.8
ENST00000424760.1
PHTF2
putative homeodomain transcription factor 2
chr13_+_24144509 0.14 ENST00000248484.4
TNFRSF19
tumor necrosis factor receptor superfamily, member 19
chr4_-_138453606 0.14 ENST00000412923.2
ENST00000344876.4
ENST00000507846.1
ENST00000510305.1
PCDH18
protocadherin 18
chr11_-_72492878 0.14 ENST00000535054.1
ENST00000545082.1
STARD10
StAR-related lipid transfer (START) domain containing 10
chr4_-_103940791 0.14 ENST00000510559.1
ENST00000394789.3
ENST00000296422.7
SLC9B1
solute carrier family 9, subfamily B (NHA1, cation proton antiporter 1), member 1
chr11_-_121986923 0.14 ENST00000560104.1
BLID
BH3-like motif containing, cell death inducer
chr12_-_86650045 0.14 ENST00000604798.1
MGAT4C
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme C (putative)
chr2_+_224822121 0.14 ENST00000258383.3
MRPL44
mitochondrial ribosomal protein L44
chr10_+_18629628 0.14 ENST00000377329.4
CACNB2
calcium channel, voltage-dependent, beta 2 subunit
chr2_-_190927447 0.14 ENST00000260950.4
MSTN
myostatin
chr2_-_27579842 0.13 ENST00000423998.1
ENST00000264720.3
GTF3C2
general transcription factor IIIC, polypeptide 2, beta 110kDa
chr17_-_41132410 0.13 ENST00000409446.3
ENST00000453594.1
ENST00000409399.1
ENST00000421990.2
PTGES3L
PTGES3L-AARSD1
prostaglandin E synthase 3 (cytosolic)-like
PTGES3L-AARSD1 readthrough
chr12_-_81763184 0.13 ENST00000548670.1
ENST00000541570.2
ENST00000553058.1
PPFIA2
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2
chr15_+_55700741 0.13 ENST00000569691.1
C15orf65
chromosome 15 open reading frame 65
chr3_+_158787098 0.13 ENST00000397832.2
ENST00000451172.1
ENST00000482126.1
IQCJ
IQ motif containing J
chr7_+_16793160 0.13 ENST00000262067.4
TSPAN13
tetraspanin 13
chr5_+_157158205 0.13 ENST00000231198.7
THG1L
tRNA-histidine guanylyltransferase 1-like (S. cerevisiae)
chr5_+_69321074 0.13 ENST00000380751.5
ENST00000380750.3
ENST00000503931.1
ENST00000506542.1
SERF1B
small EDRK-rich factor 1B (centromeric)
chr17_+_47448102 0.12 ENST00000576461.1
RP11-81K2.1
Uncharacterized protein
chr14_-_72458326 0.12 ENST00000542853.1
AC005477.1
AC005477.1
chr15_+_48483736 0.12 ENST00000417307.2
ENST00000559641.1
CTXN2
SLC12A1
cortexin 2
solute carrier family 12 (sodium/potassium/chloride transporter), member 1
chr6_-_49712072 0.12 ENST00000423399.2
CRISP3
cysteine-rich secretory protein 3
chrX_-_13835147 0.12 ENST00000493677.1
ENST00000355135.2
GPM6B
glycoprotein M6B
chr4_-_130014532 0.12 ENST00000506368.1
ENST00000439369.2
ENST00000503215.1
SCLT1
sodium channel and clathrin linker 1
chr13_+_51913819 0.12 ENST00000419898.2
SERPINE3
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 3
chr10_+_69869237 0.12 ENST00000373675.3
MYPN
myopalladin
chr1_+_109256067 0.12 ENST00000271311.2
FNDC7
fibronectin type III domain containing 7
chr1_+_214161854 0.11 ENST00000435016.1
PROX1
prospero homeobox 1
chr1_-_101360205 0.11 ENST00000450240.1
EXTL2
exostosin-like glycosyltransferase 2
chrX_+_36246735 0.11 ENST00000378653.3
CXorf30
chromosome X open reading frame 30
chrX_+_139791917 0.11 ENST00000607004.1
ENST00000370535.3
LINC00632
long intergenic non-protein coding RNA 632
chr11_-_57519253 0.11 ENST00000422652.1
ENST00000527995.1
BTBD18
BTB (POZ) domain containing 18
chr17_+_41132564 0.11 ENST00000361677.1
ENST00000589705.1
RUNDC1
RUN domain containing 1
chr6_+_72926145 0.11 ENST00000425662.2
ENST00000453976.2
RIMS1
regulating synaptic membrane exocytosis 1
chr12_+_112279782 0.10 ENST00000550735.2
MAPKAPK5
mitogen-activated protein kinase-activated protein kinase 5
chr17_+_68164752 0.10 ENST00000535240.1
KCNJ2
potassium inwardly-rectifying channel, subfamily J, member 2
chr6_-_49712091 0.10 ENST00000371159.4
CRISP3
cysteine-rich secretory protein 3
chr17_+_9479944 0.10 ENST00000396219.3
ENST00000352665.5
WDR16
WD repeat domain 16
chr5_+_101569696 0.10 ENST00000597120.1
AC008948.1
AC008948.1
chr6_-_53013620 0.10 ENST00000259803.7
GCM1
glial cells missing homolog 1 (Drosophila)
chr5_-_55412774 0.10 ENST00000434982.2
ANKRD55
ankyrin repeat domain 55
chr17_-_10452929 0.09 ENST00000532183.2
ENST00000397183.2
ENST00000420805.1
MYH2
myosin, heavy chain 2, skeletal muscle, adult
chr8_-_124279627 0.09 ENST00000357082.4
ZHX1-C8ORF76
ZHX1-C8ORF76 readthrough
chr2_+_196313239 0.09 ENST00000413290.1
AC064834.1
AC064834.1
chr5_+_59783941 0.09 ENST00000506884.1
ENST00000504876.2
PART1
prostate androgen-regulated transcript 1 (non-protein coding)
chr1_+_67632083 0.09 ENST00000347310.5
ENST00000371002.1
IL23R
interleukin 23 receptor
chr7_+_123488124 0.08 ENST00000476325.1
HYAL4
hyaluronoglucosaminidase 4
chr15_+_36887069 0.08 ENST00000566807.1
ENST00000567389.1
ENST00000562877.1
C15orf41
chromosome 15 open reading frame 41
chr12_+_96196875 0.08 ENST00000553095.1
RP11-536G4.1
Uncharacterized protein
chr8_-_27941380 0.08 ENST00000413272.2
ENST00000341513.6
NUGGC
nuclear GTPase, germinal center associated
chr5_-_10761206 0.08 ENST00000432074.2
ENST00000230895.6
DAP
death-associated protein
chr1_+_182419261 0.08 ENST00000294854.8
ENST00000542961.1
RGSL1
regulator of G-protein signaling like 1
chr9_-_107361788 0.08 ENST00000374779.2
OR13C5
olfactory receptor, family 13, subfamily C, member 5
chr12_+_26348246 0.07 ENST00000422622.2
SSPN
sarcospan
chr7_-_122339162 0.07 ENST00000340112.2
RNF133
ring finger protein 133
chr12_+_12938541 0.07 ENST00000356591.4
APOLD1
apolipoprotein L domain containing 1
chr3_-_157221380 0.07 ENST00000468233.1
VEPH1
ventricular zone expressed PH domain-containing 1
chr12_-_91505608 0.07 ENST00000266718.4
LUM
lumican
chr2_-_183291741 0.07 ENST00000351439.5
ENST00000409365.1
PDE1A
phosphodiesterase 1A, calmodulin-dependent
chr13_-_61989655 0.07 ENST00000409204.4
PCDH20
protocadherin 20
chr15_-_50558223 0.07 ENST00000267845.3
HDC
histidine decarboxylase
chr18_-_51750948 0.07 ENST00000583046.1
ENST00000398398.2
MBD2
methyl-CpG binding domain protein 2
chr2_+_204571375 0.07 ENST00000374478.4
CD28
CD28 molecule
chr2_+_166095898 0.06 ENST00000424833.1
ENST00000375437.2
ENST00000357398.3
SCN2A
sodium channel, voltage-gated, type II, alpha subunit
chr18_+_22040620 0.06 ENST00000426880.2
HRH4
histamine receptor H4
chr15_+_80364901 0.06 ENST00000560228.1
ENST00000559835.1
ENST00000559775.1
ENST00000558688.1
ENST00000560392.1
ENST00000560976.1
ENST00000558272.1
ENST00000558390.1
ZFAND6
zinc finger, AN1-type domain 6
chr17_-_39203519 0.06 ENST00000542137.1
ENST00000391419.3
KRTAP2-1
keratin associated protein 2-1
chr12_-_94673956 0.06 ENST00000551941.1
RP11-1105G2.3
Uncharacterized protein
chr2_+_149447783 0.06 ENST00000449013.1
EPC2
enhancer of polycomb homolog 2 (Drosophila)
chr21_+_35736302 0.06 ENST00000290310.3
KCNE2
potassium voltage-gated channel, Isk-related family, member 2
chr1_+_203444887 0.06 ENST00000343110.2
PRELP
proline/arginine-rich end leucine-rich repeat protein

Network of associatons between targets according to the STRING database.

First level regulatory network of HOXD4

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.4 GO:0006663 platelet activating factor biosynthetic process(GO:0006663)
0.4 1.6 GO:0048687 modulation by virus of host transcription(GO:0019056) positive regulation of sprouting of injured axon(GO:0048687) positive regulation of axon extension involved in regeneration(GO:0048691) modulation by symbiont of host transcription(GO:0052026)
0.3 4.5 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.2 0.7 GO:0072428 signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926)
0.2 0.5 GO:1904395 positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395) negative regulation of neuromuscular junction development(GO:1904397)
0.1 0.4 GO:0002416 IgG immunoglobulin transcytosis in epithelial cells mediated by FcRn immunoglobulin receptor(GO:0002416)
0.1 1.7 GO:0034392 negative regulation of smooth muscle cell apoptotic process(GO:0034392)
0.1 0.5 GO:0030806 negative regulation of cyclic nucleotide catabolic process(GO:0030806) negative regulation of cAMP catabolic process(GO:0030821) negative regulation of purine nucleotide catabolic process(GO:0033122)
0.1 0.3 GO:0099543 retrograde trans-synaptic signaling by soluble gas(GO:0098923) trans-synaptic signaling by soluble gas(GO:0099543) trans-synaptic signaling by trans-synaptic complex(GO:0099545)
0.1 0.4 GO:0090526 regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.1 0.5 GO:0061216 apoptotic process involved in endocardial cushion morphogenesis(GO:0003277) intermediate mesoderm morphogenesis(GO:0048390) intermediate mesoderm formation(GO:0048391) intermediate mesodermal cell differentiation(GO:0048392) regulation of cardiac muscle fiber development(GO:0055018) positive regulation of cardiac muscle fiber development(GO:0055020) bud dilation involved in lung branching(GO:0060503) BMP signaling pathway involved in ureter morphogenesis(GO:0061149) renal system segmentation(GO:0061150) BMP signaling pathway involved in renal system segmentation(GO:0061151) pulmonary artery endothelial tube morphogenesis(GO:0061155) regulation of transcription from RNA polymerase II promoter involved in mesonephros development(GO:0061216) BMP signaling pathway involved in nephric duct formation(GO:0071893) negative regulation of branch elongation involved in ureteric bud branching(GO:0072096) negative regulation of branch elongation involved in ureteric bud branching by BMP signaling pathway(GO:0072097) anterior/posterior pattern specification involved in ureteric bud development(GO:0072099) specification of ureteric bud anterior/posterior symmetry(GO:0072100) specification of ureteric bud anterior/posterior symmetry by BMP signaling pathway(GO:0072101) ureter epithelial cell differentiation(GO:0072192) negative regulation of mesenchymal cell proliferation involved in ureter development(GO:0072200) positive regulation of cell proliferation involved in outflow tract morphogenesis(GO:1901964) cardiac jelly development(GO:1905072) regulation of metanephric S-shaped body morphogenesis(GO:2000004) negative regulation of metanephric S-shaped body morphogenesis(GO:2000005) regulation of metanephric comma-shaped body morphogenesis(GO:2000006) negative regulation of metanephric comma-shaped body morphogenesis(GO:2000007)
0.1 0.6 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.1 0.5 GO:0044111 development involved in symbiotic interaction(GO:0044111)
0.1 0.5 GO:0050955 thermoception(GO:0050955)
0.1 0.2 GO:0000961 negative regulation of mitochondrial RNA catabolic process(GO:0000961)
0.1 1.9 GO:0032060 bleb assembly(GO:0032060)
0.1 0.4 GO:0030950 establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.1 0.6 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.1 0.9 GO:0060385 axonogenesis involved in innervation(GO:0060385)
0.1 0.3 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.1 0.4 GO:1902896 terminal web assembly(GO:1902896)
0.1 0.2 GO:0006480 N-terminal protein amino acid methylation(GO:0006480)
0.1 0.3 GO:0051958 methotrexate transport(GO:0051958)
0.1 0.6 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.1 0.4 GO:0009804 coumarin metabolic process(GO:0009804)
0.0 0.3 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.0 0.3 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.0 0.1 GO:1902725 negative regulation of skeletal muscle cell proliferation(GO:0014859) negative regulation of skeletal muscle satellite cell proliferation(GO:1902723) negative regulation of satellite cell differentiation(GO:1902725)
0.0 0.2 GO:0042414 epinephrine metabolic process(GO:0042414) cellular response to lead ion(GO:0071284)
0.0 0.1 GO:0061114 hepatocyte cell migration(GO:0002194) otic placode formation(GO:0043049) branching involved in pancreas morphogenesis(GO:0061114) acinar cell differentiation(GO:0090425) positive regulation of forebrain neuron differentiation(GO:2000979)
0.0 0.2 GO:0071934 thiamine transmembrane transport(GO:0071934)
0.0 0.5 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.0 0.5 GO:0035372 protein localization to microtubule(GO:0035372)
0.0 0.2 GO:1900262 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.0 0.2 GO:0000270 peptidoglycan metabolic process(GO:0000270) peptidoglycan catabolic process(GO:0009253)
0.0 0.5 GO:0070166 enamel mineralization(GO:0070166)
0.0 0.2 GO:0071963 establishment or maintenance of cell polarity regulating cell shape(GO:0071963)
0.0 0.1 GO:0060018 astrocyte fate commitment(GO:0060018)
0.0 0.1 GO:0001694 histamine biosynthetic process(GO:0001694)
0.0 0.3 GO:0042354 fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355)
0.0 0.1 GO:0090076 relaxation of skeletal muscle(GO:0090076)
0.0 0.1 GO:0038155 interleukin-23-mediated signaling pathway(GO:0038155)
0.0 0.3 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.0 0.1 GO:1904879 membrane depolarization during atrial cardiac muscle cell action potential(GO:0098912) positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.0 0.6 GO:0036152 phosphatidylethanolamine acyl-chain remodeling(GO:0036152)
0.0 0.1 GO:0042797 5S class rRNA transcription from RNA polymerase III type 1 promoter(GO:0042791) tRNA transcription from RNA polymerase III promoter(GO:0042797)
0.0 0.1 GO:0015808 L-alanine transport(GO:0015808)
0.0 0.2 GO:0060155 platelet dense granule organization(GO:0060155) regulation of dopamine receptor signaling pathway(GO:0060159)
0.0 0.6 GO:0035640 exploration behavior(GO:0035640)
0.0 0.2 GO:0032790 ribosome disassembly(GO:0032790)
0.0 0.7 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.0 0.1 GO:0051612 negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.0 0.1 GO:1901979 regulation of inward rectifier potassium channel activity(GO:1901979) regulation of cyclic nucleotide-gated ion channel activity(GO:1902159)
0.0 0.1 GO:0032782 bile acid secretion(GO:0032782)
0.0 0.4 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.0 0.2 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.0 0.2 GO:0097264 self proteolysis(GO:0097264)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 4.5 GO:0005577 fibrinogen complex(GO:0005577)
0.2 0.6 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.1 1.7 GO:0031089 platelet dense granule lumen(GO:0031089)
0.0 0.4 GO:1990357 terminal web(GO:1990357)
0.0 0.6 GO:0030314 junctional membrane complex(GO:0030314)
0.0 0.2 GO:0034665 integrin alpha1-beta1 complex(GO:0034665)
0.0 0.7 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 0.2 GO:0097362 MCM8-MCM9 complex(GO:0097362)
0.0 0.3 GO:0071439 clathrin complex(GO:0071439)
0.0 0.2 GO:0005663 DNA replication factor C complex(GO:0005663)
0.0 0.4 GO:0030130 clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.0 0.4 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.4 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.1 GO:0072536 interleukin-23 receptor complex(GO:0072536)
0.0 0.1 GO:0098636 protein complex involved in cell adhesion(GO:0098636)
0.0 0.4 GO:0031932 TORC2 complex(GO:0031932)
0.0 0.3 GO:0032433 filopodium tip(GO:0032433)
0.0 0.1 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.0 1.7 GO:0005811 lipid particle(GO:0005811)
0.0 0.1 GO:0005826 actomyosin contractile ring(GO:0005826)
0.0 0.5 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.1 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 0.3 GO:0035102 PRC1 complex(GO:0035102)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.7 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.2 0.6 GO:0035248 alpha-1,4-N-acetylgalactosaminyltransferase activity(GO:0035248)
0.2 0.7 GO:0072590 N-acetyl-L-aspartate-L-glutamate ligase activity(GO:0072590)
0.1 1.4 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.1 0.5 GO:0035373 chondroitin sulfate proteoglycan binding(GO:0035373)
0.1 1.6 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.1 0.4 GO:0097363 protein O-GlcNAc transferase activity(GO:0097363)
0.1 0.3 GO:0005146 leukemia inhibitory factor receptor binding(GO:0005146)
0.1 0.4 GO:0019770 IgG receptor activity(GO:0019770)
0.1 0.5 GO:0050815 phosphoserine binding(GO:0050815) phosphothreonine binding(GO:0050816)
0.1 0.2 GO:0071885 N-terminal protein N-methyltransferase activity(GO:0071885)
0.1 0.3 GO:0015350 methotrexate transporter activity(GO:0015350)
0.1 0.4 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.1 0.3 GO:0052740 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
0.1 0.3 GO:0017060 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity(GO:0017060)
0.0 0.2 GO:0015403 thiamine uptake transmembrane transporter activity(GO:0015403)
0.0 0.1 GO:0008193 tRNA guanylyltransferase activity(GO:0008193)
0.0 0.1 GO:0008511 sodium:potassium:chloride symporter activity(GO:0008511)
0.0 0.2 GO:0016532 superoxide dismutase copper chaperone activity(GO:0016532) copper-dependent protein binding(GO:0032767)
0.0 0.5 GO:0070700 BMP receptor binding(GO:0070700)
0.0 0.2 GO:0019826 oxygen sensor activity(GO:0019826)
0.0 0.5 GO:0031545 peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.0 4.2 GO:0051087 chaperone binding(GO:0051087)
0.0 0.2 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0 0.1 GO:0032296 ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
0.0 0.2 GO:0098639 collagen binding involved in cell-matrix adhesion(GO:0098639)
0.0 0.2 GO:0004969 histamine receptor activity(GO:0004969)
0.0 0.6 GO:0015278 calcium-release channel activity(GO:0015278) ligand-gated calcium channel activity(GO:0099604)
0.0 0.2 GO:0003796 lysozyme activity(GO:0003796)
0.0 0.1 GO:0042019 interleukin-23 binding(GO:0042019) interleukin-23 receptor activity(GO:0042020)
0.0 0.1 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.0 0.7 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 0.1 GO:0015180 L-alanine transmembrane transporter activity(GO:0015180) alanine transmembrane transporter activity(GO:0022858)
0.0 0.4 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.0 0.4 GO:0005248 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0 0.3 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.1 GO:0050692 DBD domain binding(GO:0050692)
0.0 0.4 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 0.0 GO:0004139 deoxyribose-phosphate aldolase activity(GO:0004139)
0.0 0.2 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934)
0.0 0.2 GO:0034483 heparan sulfate sulfotransferase activity(GO:0034483)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 4.5 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 1.8 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 0.5 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 1.0 PID INSULIN PATHWAY Insulin Pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 4.5 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.1 1.4 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.0 0.7 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.0 0.2 REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.0 0.4 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.2 REACTOME POL SWITCHING Genes involved in Polymerase switching
0.0 0.4 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 0.4 REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA Genes involved in G beta:gamma signalling through PLC beta
0.0 0.5 REACTOME CD28 DEPENDENT PI3K AKT SIGNALING Genes involved in CD28 dependent PI3K/Akt signaling