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SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for HOXD9

Z-value: 0.54

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Transcription factors associated with HOXD9

Gene Symbol Gene ID Gene Info
ENSG00000128709.10 homeobox D9

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HOXD9hg19_v2_chr2_+_176987088_176987088-0.321.6e-01Click!

Activity profile of HOXD9 motif

Sorted Z-values of HOXD9 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr18_+_61554932 3.82 ENST00000299502.4
ENST00000457692.1
ENST00000413956.1
serpin peptidase inhibitor, clade B (ovalbumin), member 2
chr10_-_105845674 3.33 ENST00000353479.5
ENST00000369733.3
collagen, type XVII, alpha 1
chr1_-_59043166 3.00 ENST00000371225.2
tumor-associated calcium signal transducer 2
chr10_-_105845536 2.55 ENST00000393211.3
collagen, type XVII, alpha 1
chr4_-_68749699 2.14 ENST00000545541.1
transmembrane protease, serine 11D
chr11_-_104972158 1.97 ENST00000598974.1
ENST00000593315.1
ENST00000594519.1
ENST00000415981.2
ENST00000525374.1
ENST00000375707.1
caspase 1, apoptosis-related cysteine peptidase
caspase recruitment domain family, member 16
caspase recruitment domain family, member 17
chr6_-_32634425 1.90 ENST00000399082.3
ENST00000399079.3
ENST00000374943.4
ENST00000434651.2
major histocompatibility complex, class II, DQ beta 1
chr18_+_21452804 1.78 ENST00000269217.6
laminin, alpha 3
chr12_-_15104040 1.73 ENST00000541644.1
ENST00000545895.1
Rho GDP dissociation inhibitor (GDI) beta
chr4_-_68749745 1.72 ENST00000283916.6
transmembrane protease, serine 11D
chr11_+_123986069 1.70 ENST00000456829.2
ENST00000361352.5
ENST00000449321.1
ENST00000392748.1
ENST00000360334.4
ENST00000392744.4
von Willebrand factor A domain containing 5A
chr4_+_71384300 1.64 ENST00000504451.1
amelotin
chr4_+_69313145 1.52 ENST00000305363.4
transmembrane protease, serine 11E
chr11_-_104905840 1.37 ENST00000526568.1
ENST00000393136.4
ENST00000531166.1
ENST00000534497.1
ENST00000527979.1
ENST00000446369.1
ENST00000353247.5
ENST00000528974.1
ENST00000533400.1
ENST00000525825.1
ENST00000436863.3
caspase 1, apoptosis-related cysteine peptidase
chr2_+_210444748 1.33 ENST00000392194.1
microtubule-associated protein 2
chr19_-_53466095 1.30 ENST00000391786.2
ENST00000434371.2
ENST00000357666.4
ENST00000438970.2
ENST00000270457.4
ENST00000535506.1
ENST00000444460.2
ENST00000457013.2
zinc finger protein 816
chr1_+_152956549 1.24 ENST00000307122.2
small proline-rich protein 1A
chr3_-_139258521 1.23 ENST00000483943.2
ENST00000232219.2
ENST00000492918.1
retinol binding protein 1, cellular
chr17_+_61151306 1.21 ENST00000580068.1
ENST00000580466.1
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
chr6_-_138833630 1.17 ENST00000533765.1
NHS-like 1
chr6_+_18387570 1.15 ENST00000259939.3
ring finger protein 144B
chr3_+_182511266 1.12 ENST00000323116.5
ENST00000493826.1
ATPase, class VI, type 11B
chr1_+_87012922 1.11 ENST00000263723.5
chloride channel accessory 4
chr4_+_71384257 1.08 ENST00000339336.4
amelotin
chr1_+_16083154 1.07 ENST00000375771.1
filamin binding LIM protein 1
chr3_-_196987309 1.07 ENST00000453607.1
discs, large homolog 1 (Drosophila)
chr15_+_49715449 1.05 ENST00000560979.1
fibroblast growth factor 7
chr5_-_39274617 0.99 ENST00000510188.1
FYN binding protein
chr1_+_87012753 0.92 ENST00000370563.3
chloride channel accessory 4
chr11_-_104827425 0.85 ENST00000393150.3
caspase 4, apoptosis-related cysteine peptidase
chr12_-_122879969 0.83 ENST00000540304.1
CAP-GLY domain containing linker protein 1
chr4_+_169633310 0.83 ENST00000510998.1
palladin, cytoskeletal associated protein
chr14_-_24733444 0.81 ENST00000560478.1
ENST00000560443.1
transglutaminase 1
chr11_+_93754513 0.80 ENST00000315765.9
hephaestin-like 1
chr12_-_88974236 0.78 ENST00000228280.5
ENST00000552044.1
ENST00000357116.4
KIT ligand
chr12_-_95009837 0.75 ENST00000551457.1
transmembrane and coiled-coil domain family 3
chr6_+_130339710 0.73 ENST00000526087.1
ENST00000533560.1
ENST00000361794.2
l(3)mbt-like 3 (Drosophila)
chr12_-_10007448 0.71 ENST00000538152.1
C-type lectin domain family 2, member B
chr4_+_186990298 0.71 ENST00000296795.3
ENST00000513189.1
toll-like receptor 3
chr6_+_149539767 0.69 ENST00000606202.1
ENST00000536230.1
ENST00000445901.1
TGF-beta activated kinase 1/MAP3K7 binding protein 2
RP1-111D6.3
chr12_+_119772502 0.68 ENST00000536742.1
ENST00000327554.2
coiled-coil domain containing 60
chr2_+_210518057 0.68 ENST00000452717.1
microtubule-associated protein 2
chr1_-_9953295 0.67 ENST00000377258.1
catenin, beta interacting protein 1
chr5_-_78808617 0.65 ENST00000282260.6
ENST00000508576.1
ENST00000535690.1
homer homolog 1 (Drosophila)
chr1_+_81771806 0.64 ENST00000370721.1
ENST00000370727.1
ENST00000370725.1
ENST00000370723.1
ENST00000370728.1
ENST00000370730.1
latrophilin 2
chr9_+_70856397 0.63 ENST00000360171.6
COBW domain containing 3
chr11_-_46639436 0.62 ENST00000532281.1
harbinger transposase derived 1
chr3_-_195310802 0.61 ENST00000421243.1
ENST00000453131.1
apolipoprotein D
chr4_+_37455536 0.61 ENST00000381980.4
ENST00000508175.1
chromosome 4 open reading frame 19
chr2_+_210517895 0.61 ENST00000447185.1
microtubule-associated protein 2
chr19_+_45843994 0.60 ENST00000391946.2
kinesin light chain 3
chr6_+_15401075 0.59 ENST00000541660.1
jumonji, AT rich interactive domain 2
chr1_+_78383813 0.59 ENST00000342754.5
nexilin (F actin binding protein)
chr17_+_61086917 0.59 ENST00000424789.2
ENST00000389520.4
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
chr20_-_20693131 0.58 ENST00000202677.7
Ral GTPase activating protein, alpha subunit 2 (catalytic)
chr4_-_83765613 0.58 ENST00000503937.1
SEC31 homolog A (S. cerevisiae)
chr16_+_4545853 0.57 ENST00000575129.1
ENST00000398595.3
ENST00000414777.1
heme oxygenase (decycling) 2
chr7_+_6713376 0.56 ENST00000399484.3
ENST00000544825.1
ENST00000401847.1
Uncharacterized protein
chr7_-_130353553 0.56 ENST00000330992.7
ENST00000445977.2
coatomer protein complex, subunit gamma 2
chr22_-_19466643 0.55 ENST00000474226.1
ubiquitin fusion degradation 1 like (yeast)
chr1_+_38022513 0.54 ENST00000296218.7
dynein, axonemal, light intermediate chain 1
chr1_+_16083098 0.54 ENST00000496928.2
ENST00000508310.1
filamin binding LIM protein 1
chr3_+_107364769 0.53 ENST00000449271.1
ENST00000425868.1
ENST00000449213.1
bobby sox homolog (Drosophila)
chr11_+_69924639 0.53 ENST00000538023.1
ENST00000398543.2
anoctamin 1, calcium activated chloride channel
chr17_+_44679808 0.53 ENST00000571172.1
N-ethylmaleimide-sensitive factor
chr2_+_135809835 0.53 ENST00000264158.8
ENST00000539493.1
ENST00000442034.1
ENST00000425393.1
RAB3 GTPase activating protein subunit 1 (catalytic)
chr17_+_66521936 0.52 ENST00000592800.1
protein kinase, cAMP-dependent, regulatory, type I, alpha
chr7_-_92777606 0.51 ENST00000437805.1
ENST00000446959.1
ENST00000439952.1
ENST00000414791.1
ENST00000446033.1
ENST00000411955.1
ENST00000318238.4
sterile alpha motif domain containing 9-like
chr1_+_160370344 0.51 ENST00000368061.2
VANGL planar cell polarity protein 2
chr6_+_45390222 0.51 ENST00000359524.5
runt-related transcription factor 2
chr11_-_16430399 0.51 ENST00000528252.1
SRY (sex determining region Y)-box 6
chr8_+_79503458 0.50 ENST00000518467.1
protein kinase (cAMP-dependent, catalytic) inhibitor alpha
chr3_-_99569821 0.50 ENST00000487087.1
filamin A interacting protein 1-like
chr20_+_19870167 0.50 ENST00000440354.2
Ras and Rab interactor 2
chr8_-_42396185 0.49 ENST00000518717.1
solute carrier family 20 (phosphate transporter), member 2
chr20_-_39928756 0.48 ENST00000432768.2
zinc fingers and homeoboxes 3
chr14_+_62164340 0.48 ENST00000557538.1
ENST00000539097.1
hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
chr3_-_182703688 0.48 ENST00000466812.1
ENST00000487822.1
ENST00000460412.1
ENST00000469954.1
DCN1, defective in cullin neddylation 1, domain containing 1
chr18_-_5396271 0.48 ENST00000579951.1
erythrocyte membrane protein band 4.1-like 3
chr4_+_75174180 0.46 ENST00000413830.1
epithelial mitogen
chr4_-_146859787 0.46 ENST00000508784.1
zinc finger protein 827
chr8_+_104892639 0.45 ENST00000436393.2
regulating synaptic membrane exocytosis 2
chr1_+_82165350 0.44 ENST00000359929.3
latrophilin 2
chr2_-_128284020 0.44 ENST00000295321.4
ENST00000455721.2
IWS1 homolog (S. cerevisiae)
chr4_-_120225600 0.43 ENST00000399075.4
chromosome 4 open reading frame 3
chr13_+_76413852 0.43 ENST00000533809.2
LIM domain 7
chr2_+_234668894 0.43 ENST00000305208.5
ENST00000608383.1
ENST00000360418.3
UDP glucuronosyltransferase 1 family, polypeptide A1
UDP glucuronosyltransferase 1 family, polypeptide A8
chrX_-_68385274 0.43 ENST00000374584.3
ENST00000590146.1
praja ring finger 1, E3 ubiquitin protein ligase
chr12_-_118628350 0.42 ENST00000537952.1
ENST00000537822.1
TAO kinase 3
chr10_-_28623368 0.42 ENST00000441595.2
membrane protein, palmitoylated 7 (MAGUK p55 subfamily member 7)
chr2_+_234627424 0.42 ENST00000373409.3
UDP glucuronosyltransferase 1 family, polypeptide A4
chrX_-_68385354 0.42 ENST00000361478.1
praja ring finger 1, E3 ubiquitin protein ligase
chr7_+_123469037 0.41 ENST00000489978.1
hyaluronoglucosaminidase 4
chr7_-_107204706 0.41 ENST00000393603.2
component of oligomeric golgi complex 5
chr12_+_19358228 0.41 ENST00000424268.1
ENST00000543806.1
pleckstrin homology domain containing, family A member 5
chr3_+_107318157 0.41 ENST00000406780.1
bobby sox homolog (Drosophila)
chr11_-_128457446 0.41 ENST00000392668.4
v-ets avian erythroblastosis virus E26 oncogene homolog 1
chr1_-_95391315 0.40 ENST00000545882.1
ENST00000415017.1
calponin 3, acidic
chr3_+_102153859 0.38 ENST00000306176.1
ENST00000466937.1
zona pellucida-like domain containing 1
chr7_+_18536090 0.37 ENST00000441986.1
histone deacetylase 9
chr11_-_105010320 0.35 ENST00000532895.1
ENST00000530950.1
caspase recruitment domain family, member 18
chr10_+_86184676 0.35 ENST00000543283.1
coiled-coil serine-rich protein 2
chr12_-_91546926 0.35 ENST00000550758.1
decorin
chr15_-_49913126 0.35 ENST00000561064.1
ENST00000299338.6
family with sequence similarity 227, member B
chr2_+_191334212 0.35 ENST00000444317.1
ENST00000535751.1
major facilitator superfamily domain containing 6
chr4_+_74606223 0.33 ENST00000307407.3
ENST00000401931.1
interleukin 8
chr3_+_107364683 0.33 ENST00000413213.1
bobby sox homolog (Drosophila)
chr4_-_76944621 0.33 ENST00000306602.1
chemokine (C-X-C motif) ligand 10
chr4_-_69434245 0.33 ENST00000317746.2
UDP glucuronosyltransferase 2 family, polypeptide B17
chr1_-_21377383 0.32 ENST00000374935.3
eukaryotic translation initiation factor 4 gamma, 3
chr11_+_69924679 0.31 ENST00000531604.1
anoctamin 1, calcium activated chloride channel
chr9_+_20927764 0.31 ENST00000603044.1
ENST00000604254.1
focadhesin
chr16_-_66764119 0.30 ENST00000569320.1
dynein, cytoplasmic 1, light intermediate chain 2
chr7_+_90012986 0.29 ENST00000416322.1
claudin 12
chr18_-_46895066 0.29 ENST00000583225.1
ENST00000584983.1
ENST00000583280.1
ENST00000581738.1
dymeclin
chr8_-_71157595 0.28 ENST00000519724.1
nuclear receptor coactivator 2
chr18_-_57027194 0.28 ENST00000251047.5
lectin, mannose-binding, 1
chr1_+_16083123 0.28 ENST00000510393.1
ENST00000430076.1
filamin binding LIM protein 1
chr11_+_12115543 0.28 ENST00000537344.1
ENST00000532179.1
ENST00000526065.1
microtubule associated monooxygenase, calponin and LIM domain containing 2
chr1_-_197036364 0.28 ENST00000367412.1
coagulation factor XIII, B polypeptide
chrX_-_77150911 0.27 ENST00000373336.3
magnesium transporter 1
chr10_+_115511213 0.25 ENST00000361048.1
pleckstrin homology domain containing, family S member 1
chr5_-_147211226 0.25 ENST00000296695.5
serine peptidase inhibitor, Kazal type 1
chr22_-_19466683 0.25 ENST00000399523.1
ENST00000421968.2
ENST00000447868.1
ubiquitin fusion degradation 1 like (yeast)
chr3_+_195413160 0.25 ENST00000599448.1
long intergenic non-protein coding RNA 969
chr3_-_107777208 0.25 ENST00000398258.3
CD47 molecule
chr6_-_31632962 0.24 ENST00000456540.1
ENST00000445768.1
G patch domain and ankyrin repeats 1
chr13_-_33924755 0.24 ENST00000439831.1
ENST00000567873.1
StAR-related lipid transfer (START) domain containing 13
chr19_+_10397648 0.24 ENST00000340992.4
ENST00000393717.2
intercellular adhesion molecule 4 (Landsteiner-Wiener blood group)
chr5_+_158654712 0.24 ENST00000520323.1
CTB-11I22.2
chr13_+_33160553 0.23 ENST00000315596.10
PDS5, regulator of cohesion maintenance, homolog B (S. cerevisiae)
chr15_+_52155001 0.23 ENST00000544199.1
tropomodulin 3 (ubiquitous)
chr9_+_96846740 0.23 ENST00000288976.3
protein tyrosine phosphatase domain containing 1
chr14_+_57671888 0.21 ENST00000391612.1
AL391152.1
chr17_+_75181292 0.21 ENST00000431431.2
SEC14-like 1 (S. cerevisiae)
chr10_-_71169031 0.20 ENST00000373307.1
tachykinin receptor 2
chr2_+_181988560 0.19 ENST00000424170.1
ENST00000435411.1
AC104820.2
chr2_+_181988620 0.18 ENST00000428474.1
ENST00000424655.1
AC104820.2
chr5_+_112043186 0.18 ENST00000509732.1
ENST00000457016.1
ENST00000507379.1
adenomatous polyposis coli
chr22_-_41682172 0.17 ENST00000356244.3
Ran GTPase activating protein 1
chr15_-_39486510 0.17 ENST00000560743.1
RP11-265N7.1
chr13_-_81801115 0.17 ENST00000567258.1
long intergenic non-protein coding RNA 564
chr7_-_92146729 0.16 ENST00000541751.1
peroxisomal biogenesis factor 1
chr2_-_70417827 0.16 ENST00000457952.1
chromosome 2 open reading frame 42
chr4_-_185395191 0.16 ENST00000510814.1
ENST00000507523.1
ENST00000506230.1
interferon regulatory factor 2
chr11_-_78052923 0.16 ENST00000340149.2
GRB2-associated binding protein 2
chr11_+_63606373 0.16 ENST00000402010.2
ENST00000315032.8
ENST00000377809.4
ENST00000413835.2
ENST00000377810.3
MAP/microtubule affinity-regulating kinase 2
chr7_+_5920429 0.15 ENST00000242104.5
oncomodulin
chr22_-_19466732 0.15 ENST00000263202.10
ENST00000360834.4
ubiquitin fusion degradation 1 like (yeast)
chr2_+_185463093 0.15 ENST00000302277.6
zinc finger protein 804A
chr17_+_57233087 0.15 ENST00000578777.1
ENST00000577457.1
ENST00000582995.1
proline rich 11
chr6_+_31021225 0.14 ENST00000565192.1
ENST00000562344.1
HLA complex group 22
chr14_-_38028689 0.13 ENST00000553425.1
RP11-356O9.2
chr1_-_152196669 0.13 ENST00000368801.2
hornerin
chr2_+_109223595 0.13 ENST00000410093.1
LIM and senescent cell antigen-like domains 1
chr2_-_207078154 0.13 ENST00000447845.1
G protein-coupled receptor 1
chr4_-_72649763 0.12 ENST00000513476.1
group-specific component (vitamin D binding protein)
chr4_-_110723194 0.12 ENST00000394635.3
complement factor I
chr12_-_95510743 0.12 ENST00000551521.1
FYVE, RhoGEF and PH domain containing 6
chr6_+_46761118 0.12 ENST00000230588.4
meprin A, alpha (PABA peptide hydrolase)
chr5_-_119669160 0.12 ENST00000514240.1
CTC-552D5.1
chr2_-_188312971 0.12 ENST00000410068.1
ENST00000447403.1
ENST00000410102.1
calcitonin receptor-like
chr12_+_19358192 0.11 ENST00000538305.1
pleckstrin homology domain containing, family A member 5
chr9_+_124103625 0.11 ENST00000594963.1
Uncharacterized protein
chr5_-_111093167 0.10 ENST00000446294.2
ENST00000419114.2
neuronal regeneration related protein
chr18_-_53069419 0.10 ENST00000570177.2
transcription factor 4
chr4_-_84035868 0.10 ENST00000426923.2
ENST00000509973.1
placenta-specific 8
chr19_-_19739321 0.10 ENST00000588461.1
lysophosphatidic acid receptor 2
chr14_+_23709555 0.10 ENST00000430154.2
chromosome 14 open reading frame 164
chr2_-_166702601 0.10 ENST00000428888.1
AC009495.4
chr6_-_39399087 0.10 ENST00000229913.5
ENST00000541946.1
ENST00000394362.1
kinesin family member 6
chr5_+_140588269 0.10 ENST00000541609.1
ENST00000239450.2
protocadherin beta 12
chr13_+_111748183 0.10 ENST00000422994.1
long intergenic non-protein coding RNA 368
chr14_+_62462541 0.10 ENST00000430451.2
synaptotagmin XVI
chrX_-_33229636 0.09 ENST00000357033.4
dystrophin
chr21_-_31588365 0.09 ENST00000399899.1
claudin 8
chr1_+_146373546 0.09 ENST00000446760.2
neuroblastoma breakpoint family, member 12
chr6_+_53948328 0.09 ENST00000370876.2
muscular LMNA-interacting protein
chr14_+_23654525 0.08 ENST00000399910.1
ENST00000492621.1
chromosome 14 open reading frame 164
chr4_-_36245561 0.08 ENST00000506189.1
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr1_-_236046872 0.08 ENST00000536965.1
lysosomal trafficking regulator
chr6_+_131958436 0.08 ENST00000357639.3
ENST00000543135.1
ENST00000427148.2
ENST00000358229.5
ectonucleotide pyrophosphatase/phosphodiesterase 3
chr12_-_11002063 0.08 ENST00000544994.1
ENST00000228811.4
ENST00000540107.1
proline rich 4 (lacrimal)
chr2_+_28824786 0.08 ENST00000541605.1
phospholipase B1
chr12_-_118797475 0.07 ENST00000541786.1
ENST00000419821.2
ENST00000541878.1
TAO kinase 3
chr4_-_70361579 0.07 ENST00000512583.1
UDP glucuronosyltransferase 2 family, polypeptide B4
chr14_-_36645674 0.07 ENST00000556013.2
papillary thyroid carcinoma susceptibility candidate 3 (non-protein coding)
chr13_-_47012325 0.07 ENST00000409879.2
KIAA0226-like
chr3_+_62936098 0.07 ENST00000475886.1
ENST00000465684.1
ENST00000465262.1
ENST00000468072.1
long intergenic non-protein coding RNA 698
chr6_-_74231444 0.07 ENST00000331523.2
ENST00000356303.2
eukaryotic translation elongation factor 1 alpha 1
chr13_+_46039037 0.06 ENST00000349995.5
component of oligomeric golgi complex 3
chr7_-_5998714 0.06 ENST00000539903.1
radial spoke head 10 homolog B (Chlamydomonas)
chr18_+_616672 0.06 ENST00000338387.7
clusterin-like 1 (retinal)
chr4_-_70361615 0.06 ENST00000305107.6
UDP glucuronosyltransferase 2 family, polypeptide B4
chr18_-_24443151 0.06 ENST00000440832.3
aquaporin 4
chr6_-_133055815 0.05 ENST00000509351.1
ENST00000417437.2
ENST00000414302.2
ENST00000423615.2
ENST00000427187.2
ENST00000275223.3
ENST00000519686.2
vanin 3
chr16_+_21689835 0.05 ENST00000286149.4
ENST00000388958.3
otoancorin
chr7_+_120629653 0.05 ENST00000450913.2
ENST00000340646.5
cadherin-like and PC-esterase domain containing 1
chr14_-_68000442 0.05 ENST00000554278.1
transmembrane protein 229B
chr3_-_27498235 0.05 ENST00000295736.5
ENST00000428386.1
ENST00000428179.1
solute carrier family 4, sodium bicarbonate cotransporter, member 7

Network of associatons between targets according to the STRING database.

First level regulatory network of HOXD9

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.7 GO:0070175 positive regulation of enamel mineralization(GO:0070175)
0.8 3.3 GO:0050717 positive regulation of interleukin-1 alpha secretion(GO:0050717)
0.3 3.0 GO:0090191 negative regulation of branching involved in ureteric bud morphogenesis(GO:0090191)
0.3 0.8 GO:0033023 mast cell homeostasis(GO:0033023) mast cell apoptotic process(GO:0033024) regulation of mast cell apoptotic process(GO:0033025) regulation of mast cell proliferation(GO:0070666) positive regulation of mast cell proliferation(GO:0070668)
0.2 1.7 GO:0071461 cellular response to redox state(GO:0071461)
0.2 1.1 GO:0015917 aminophospholipid transport(GO:0015917)
0.2 7.7 GO:0031581 hemidesmosome assembly(GO:0031581)
0.2 0.7 GO:0034343 type III interferon production(GO:0034343) regulation of type III interferon production(GO:0034344) positive regulation of interferon-alpha biosynthetic process(GO:0045356)
0.2 0.5 GO:1903371 establishment of protein localization to endoplasmic reticulum membrane(GO:0097051) regulation of endoplasmic reticulum tubular network organization(GO:1903371)
0.2 1.0 GO:0060437 lung growth(GO:0060437)
0.2 0.5 GO:0060489 orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490)
0.2 0.6 GO:0007206 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
0.2 0.6 GO:2000097 regulation of smooth muscle cell-matrix adhesion(GO:2000097)
0.1 0.4 GO:0097198 histone H3-K36 trimethylation(GO:0097198)
0.1 0.6 GO:0006788 heme oxidation(GO:0006788)
0.1 0.8 GO:0006789 bilirubin conjugation(GO:0006789)
0.1 0.9 GO:0043163 cell envelope organization(GO:0043163) external encapsulating structure organization(GO:0045229)
0.1 0.7 GO:0002528 regulation of vascular permeability involved in acute inflammatory response(GO:0002528)
0.1 0.8 GO:0044861 protein transport into plasma membrane raft(GO:0044861)
0.1 1.1 GO:1903764 regulation of potassium ion export across plasma membrane(GO:1903764)
0.1 0.5 GO:0051541 neural fold elevation formation(GO:0021502) elastin metabolic process(GO:0051541) epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030) positive regulation of chemokine-mediated signaling pathway(GO:0070101)
0.1 0.3 GO:1904017 cellular response to Thyroglobulin triiodothyronine(GO:1904017)
0.1 0.9 GO:1903265 positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
0.1 1.9 GO:0033623 regulation of integrin activation(GO:0033623)
0.1 3.8 GO:0042730 fibrinolysis(GO:0042730)
0.1 0.5 GO:0021778 oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780)
0.1 1.2 GO:0006776 vitamin A metabolic process(GO:0006776)
0.1 1.2 GO:0097475 motor neuron migration(GO:0097475)
0.1 0.3 GO:0019417 sulfur oxidation(GO:0019417)
0.1 0.8 GO:0015705 iodide transport(GO:0015705)
0.1 0.5 GO:0035494 SNARE complex disassembly(GO:0035494)
0.1 0.5 GO:0002175 protein localization to paranode region of axon(GO:0002175)
0.1 0.4 GO:0030578 PML body organization(GO:0030578)
0.1 0.3 GO:0010751 negative regulation of nitric oxide mediated signal transduction(GO:0010751)
0.0 0.2 GO:0033685 negative regulation of luteinizing hormone secretion(GO:0033685)
0.0 1.0 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0 0.7 GO:0043249 erythrocyte maturation(GO:0043249)
0.0 0.1 GO:0006711 estrogen catabolic process(GO:0006711)
0.0 0.2 GO:1904117 response to vasopressin(GO:1904116) cellular response to vasopressin(GO:1904117)
0.0 0.4 GO:0071896 protein localization to adherens junction(GO:0071896)
0.0 0.2 GO:0097498 endothelial tube lumen extension(GO:0097498)
0.0 0.2 GO:0060151 peroxisome localization(GO:0060151) microtubule-based peroxisome localization(GO:0060152)
0.0 0.6 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.0 3.6 GO:0007585 respiratory gaseous exchange(GO:0007585)
0.0 0.6 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.0 0.5 GO:0098814 spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.0 0.5 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.0 0.5 GO:0042487 regulation of odontogenesis of dentin-containing tooth(GO:0042487)
0.0 0.4 GO:0061458 reproductive system development(GO:0061458)
0.0 0.3 GO:0010819 regulation of T cell chemotaxis(GO:0010819)
0.0 0.4 GO:0050713 negative regulation of interleukin-1 beta secretion(GO:0050713)
0.0 0.5 GO:0045741 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741)
0.0 0.5 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.0 0.3 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.0 0.6 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 0.1 GO:0033364 mast cell secretory granule organization(GO:0033364)
0.0 0.1 GO:0030505 inorganic diphosphate transport(GO:0030505)
0.0 0.8 GO:0006825 copper ion transport(GO:0006825)
0.0 0.6 GO:0003334 keratinocyte development(GO:0003334)
0.0 1.2 GO:0018149 peptide cross-linking(GO:0018149)
0.0 0.5 GO:0045116 protein neddylation(GO:0045116)
0.0 0.2 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.0 0.4 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.0 2.7 GO:0001578 microtubule bundle formation(GO:0001578)
0.0 0.2 GO:1904885 beta-catenin destruction complex assembly(GO:1904885)
0.0 1.0 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 0.1 GO:0034285 response to sucrose(GO:0009744) response to disaccharide(GO:0034285)
0.0 0.1 GO:1904588 cellular response to glycoprotein(GO:1904588) cellular response to thyrotropin-releasing hormone(GO:1905229)
0.0 0.3 GO:0052695 cellular glucuronidation(GO:0052695)
0.0 0.4 GO:0030207 chondroitin sulfate catabolic process(GO:0030207)
0.0 0.3 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.0 0.2 GO:0015693 magnesium ion transport(GO:0015693)
0.0 1.0 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.0 0.2 GO:0039536 negative regulation of RIG-I signaling pathway(GO:0039536)
0.0 1.2 GO:0002381 immunoglobulin production involved in immunoglobulin mediated immune response(GO:0002381)
0.0 0.4 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.0 1.9 GO:1902476 chloride transmembrane transport(GO:1902476)
0.0 0.4 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 3.3 GO:0072558 NLRP1 inflammasome complex(GO:0072558) protease inhibitor complex(GO:0097179)
0.3 2.6 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.2 5.9 GO:0030056 hemidesmosome(GO:0030056)
0.2 0.9 GO:0097169 AIM2 inflammasome complex(GO:0097169)
0.2 1.8 GO:0005610 laminin-5 complex(GO:0005610)
0.1 0.5 GO:0060187 cell pole(GO:0060187)
0.1 3.8 GO:0005605 basal lamina(GO:0005605)
0.1 1.9 GO:0042613 MHC class II protein complex(GO:0042613)
0.1 0.8 GO:0044352 pinosome(GO:0044352) macropinosome(GO:0044354)
0.1 3.0 GO:0009925 basal plasma membrane(GO:0009925)
0.1 0.2 GO:1990723 cytoplasmic periphery of the nuclear pore complex(GO:1990723)
0.1 0.4 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.0 0.3 GO:0033655 host cell cytoplasm(GO:0030430) host cell cytoplasm part(GO:0033655)
0.0 0.1 GO:0036457 keratohyalin granule(GO:0036457)
0.0 0.6 GO:0035253 ciliary rootlet(GO:0035253)
0.0 0.8 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.0 0.6 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 2.0 GO:0001533 cornified envelope(GO:0001533)
0.0 0.7 GO:0036020 endolysosome membrane(GO:0036020)
0.0 0.6 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.5 GO:0017119 Golgi transport complex(GO:0017119)
0.0 0.5 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.4 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 0.7 GO:0043034 costamere(GO:0043034)
0.0 0.2 GO:0098647 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.0 0.6 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.5 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.0 1.9 GO:0097517 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 0.3 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 1.3 GO:0035577 azurophil granule membrane(GO:0035577)
0.0 0.8 GO:0030286 dynein complex(GO:0030286)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.8 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.2 4.6 GO:0050700 CARD domain binding(GO:0050700)
0.1 1.7 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.1 0.6 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.1 1.9 GO:0032395 MHC class II receptor activity(GO:0032395)
0.1 0.8 GO:0015111 iodide transmembrane transporter activity(GO:0015111)
0.1 1.2 GO:0030280 structural constituent of epidermis(GO:0030280)
0.1 1.1 GO:0097016 L27 domain binding(GO:0097016)
0.1 0.3 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.1 2.4 GO:0002162 dystroglycan binding(GO:0002162)
0.1 1.9 GO:0031005 filamin binding(GO:0031005)
0.1 0.8 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.1 2.0 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.1 0.8 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.1 0.3 GO:0010861 thyroid hormone receptor activator activity(GO:0010861) thyroid hormone receptor coactivator activity(GO:0030375)
0.1 0.5 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.0 0.2 GO:0004995 tachykinin receptor activity(GO:0004995)
0.0 1.2 GO:0016918 retinal binding(GO:0016918) retinol binding(GO:0019841)
0.0 0.1 GO:1902271 D3 vitamins binding(GO:1902271)
0.0 1.1 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.8 GO:0045504 dynein heavy chain binding(GO:0045504)
0.0 1.0 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.0 1.0 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.2 GO:0039552 RIG-I binding(GO:0039552)
0.0 0.4 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)
0.0 1.2 GO:0001972 retinoic acid binding(GO:0001972)
0.0 0.1 GO:0004948 calcitonin receptor activity(GO:0004948)
0.0 1.6 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.6 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.0 1.0 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.5 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 0.7 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.6 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 2.8 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.9 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 0.2 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.0 0.1 GO:0035529 NADH pyrophosphatase activity(GO:0035529)
0.0 0.1 GO:0050253 retinyl-palmitate esterase activity(GO:0050253)
0.0 0.3 GO:0005537 mannose binding(GO:0005537)
0.0 0.6 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0 0.2 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0 0.5 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 1.0 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.4 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0 0.0 GO:0031626 beta-endorphin binding(GO:0031626)
0.0 0.4 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.2 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.1 5.8 NABA COLLAGENS Genes encoding collagen proteins
0.1 1.8 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 1.5 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.0 1.1 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 2.8 PID LKB1 PATHWAY LKB1 signaling events
0.0 2.6 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 0.8 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 0.7 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 1.0 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 1.1 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 0.8 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.3 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.1 5.8 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.1 1.4 REACTOME TRAF6 MEDIATED INDUCTION OF TAK1 COMPLEX Genes involved in TRAF6 mediated induction of TAK1 complex
0.0 1.0 REACTOME ACTIVATED POINT MUTANTS OF FGFR2 Genes involved in Activated point mutants of FGFR2
0.0 1.9 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 1.2 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 1.1 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.8 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.0 1.2 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 0.6 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.2 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 1.1 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 2.2 REACTOME CELL JUNCTION ORGANIZATION Genes involved in Cell junction organization
0.0 0.6 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 0.8 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.9 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.0 0.3 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 0.6 REACTOME KINESINS Genes involved in Kinesins
0.0 0.5 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0 0.5 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 0.3 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 0.5 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB