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SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for HSF1

Z-value: 0.50

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Transcription factors associated with HSF1

Gene Symbol Gene ID Gene Info
ENSG00000185122.6 heat shock transcription factor 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HSF1hg19_v2_chr8_+_145515263_145515299-0.623.6e-03Click!

Activity profile of HSF1 motif

Sorted Z-values of HSF1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr12_-_52911718 2.24 ENST00000548409.1
keratin 5
chr17_-_39661849 1.75 ENST00000246635.3
ENST00000336861.3
ENST00000587544.1
ENST00000587435.1
keratin 13
chr16_+_56659687 1.30 ENST00000568293.1
ENST00000330439.6
metallothionein 1E
chr1_-_153363452 1.22 ENST00000368732.1
ENST00000368733.3
S100 calcium binding protein A8
chr17_-_39928106 1.22 ENST00000540235.1
junction plakoglobin
chr11_-_104840093 1.15 ENST00000417440.2
ENST00000444739.2
caspase 4, apoptosis-related cysteine peptidase
chrX_-_73072534 1.14 ENST00000429829.1
X inactive specific transcript (non-protein coding)
chr17_-_39661947 1.14 ENST00000590425.1
keratin 13
chr8_+_124194752 1.13 ENST00000318462.6
family with sequence similarity 83, member A
chr1_+_35247859 1.13 ENST00000373362.3
gap junction protein, beta 3, 31kDa
chr2_+_237476419 0.99 ENST00000447924.1
atypical chemokine receptor 3
chr7_+_157129738 0.94 ENST00000437030.1
DnaJ (Hsp40) homolog, subfamily B, member 6
chr17_-_39677971 0.91 ENST00000393976.2
keratin 15
chr6_+_35265586 0.85 ENST00000542066.1
ENST00000316637.5
differentially expressed in FDCP 6 homolog (mouse)
chr11_-_104905840 0.81 ENST00000526568.1
ENST00000393136.4
ENST00000531166.1
ENST00000534497.1
ENST00000527979.1
ENST00000446369.1
ENST00000353247.5
ENST00000528974.1
ENST00000533400.1
ENST00000525825.1
ENST00000436863.3
caspase 1, apoptosis-related cysteine peptidase
chr6_+_47666275 0.79 ENST00000327753.3
ENST00000283303.2
G protein-coupled receptor 115
chr19_-_36004543 0.75 ENST00000339686.3
ENST00000447113.2
ENST00000440396.1
dermokine
chr2_+_113735575 0.74 ENST00000376489.2
ENST00000259205.4
interleukin 36, gamma
chr19_-_51522955 0.71 ENST00000358789.3
kallikrein-related peptidase 10
chr7_-_3083573 0.70 ENST00000396946.4
caspase recruitment domain family, member 11
chr7_+_150020363 0.65 ENST00000359623.4
ENST00000493307.1
leucine rich repeat containing 61
chr2_-_56150910 0.64 ENST00000424836.2
ENST00000438672.1
ENST00000440439.1
ENST00000429909.1
ENST00000424207.1
ENST00000452337.1
ENST00000355426.3
ENST00000439193.1
ENST00000421664.1
EGF containing fibulin-like extracellular matrix protein 1
chr11_+_123986069 0.64 ENST00000456829.2
ENST00000361352.5
ENST00000449321.1
ENST00000392748.1
ENST00000360334.4
ENST00000392744.4
von Willebrand factor A domain containing 5A
chr11_+_34645791 0.62 ENST00000529527.1
ENST00000531728.1
ENST00000525253.1
ets homologous factor
chr19_-_51456344 0.62 ENST00000336334.3
ENST00000593428.1
kallikrein-related peptidase 5
chr18_+_21452804 0.60 ENST00000269217.6
laminin, alpha 3
chr19_-_53193731 0.59 ENST00000598536.1
ENST00000594682.2
ENST00000601257.1
zinc finger protein 83
chr19_-_12444306 0.59 ENST00000594577.1
ENST00000601858.1
zinc finger protein 563
chr14_+_24837226 0.58 ENST00000554050.1
ENST00000554903.1
ENST00000554779.1
ENST00000250373.4
ENST00000553708.1
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4
chr19_-_51523412 0.57 ENST00000391805.1
ENST00000599077.1
kallikrein-related peptidase 10
chr1_+_19970202 0.57 ENST00000439664.1
neuroblastoma 1, DAN family BMP antagonist
chr14_-_24809154 0.57 ENST00000216274.5
receptor-interacting serine-threonine kinase 3
chr18_+_21452964 0.57 ENST00000587184.1
laminin, alpha 3
chr6_-_32784687 0.56 ENST00000447394.1
ENST00000438763.2
major histocompatibility complex, class II, DO beta
chr19_-_6720686 0.54 ENST00000245907.6
complement component 3
chr6_-_170599561 0.54 ENST00000366756.3
delta-like 1 (Drosophila)
chr4_-_77819002 0.53 ENST00000334306.2
sosondowah ankyrin repeat domain family member B
chr16_-_79634595 0.53 ENST00000326043.4
ENST00000393350.1
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog
chr6_+_46620676 0.52 ENST00000371347.5
ENST00000411689.2
solute carrier family 25, member 27
chr7_+_150020329 0.51 ENST00000323078.7
leucine rich repeat containing 61
chr19_-_2051223 0.50 ENST00000309340.7
ENST00000589534.1
ENST00000250896.3
ENST00000589509.1
MAP kinase interacting serine/threonine kinase 2
chr19_-_51456198 0.50 ENST00000594846.1
kallikrein-related peptidase 5
chr19_-_51523275 0.50 ENST00000309958.3
kallikrein-related peptidase 10
chr4_+_106816644 0.49 ENST00000506666.1
ENST00000503451.1
nephronectin
chr1_-_27682962 0.49 ENST00000486046.1
mitogen-activated protein kinase kinase kinase 6
chr12_-_123011476 0.49 ENST00000528279.1
ENST00000344591.4
ENST00000526560.2
arginine/serine-rich coiled-coil 2
chrX_+_147062844 0.48 ENST00000370467.3
fragile X mental retardation 1 neighbor
chr19_-_2085323 0.48 ENST00000591638.1
MOB kinase activator 3A
chr15_-_72490114 0.47 ENST00000309731.7
GRAM domain containing 2
chr1_-_183538319 0.47 ENST00000420553.1
ENST00000419402.1
neutrophil cytosolic factor 2
chr1_+_10003486 0.46 ENST00000403197.1
ENST00000377205.1
nicotinamide nucleotide adenylyltransferase 1
chr1_+_161494036 0.45 ENST00000309758.4
heat shock 70kDa protein 6 (HSP70B')
chr11_-_111782696 0.44 ENST00000227251.3
ENST00000526180.1
crystallin, alpha B
chr17_+_8339340 0.44 ENST00000580012.1
nudE neurodevelopment protein 1-like 1
chr11_-_125773085 0.44 ENST00000227474.3
ENST00000534158.1
ENST00000529801.1
pseudouridylate synthase 3
chr2_-_220142892 0.44 ENST00000427737.1
tubulin, alpha 4a
chr2_-_241831424 0.44 ENST00000402775.2
ENST00000307486.8
chromosome 2 open reading frame 54
chr21_+_35445827 0.43 ENST00000608209.1
ENST00000381151.3
sodium/myo-inositol cotransporter
solute carrier family 5 (sodium/myo-inositol cotransporter), member 3
chr2_+_47596287 0.41 ENST00000263735.4
epithelial cell adhesion molecule
chr11_+_10471836 0.41 ENST00000444303.2
adenosine monophosphate deaminase 3
chr20_-_62168714 0.40 ENST00000542869.1
protein tyrosine kinase 6
chr6_-_38607628 0.40 ENST00000498633.1
BTB (POZ) domain containing 9
chr2_-_151395525 0.40 ENST00000439275.1
Rho family GTPase 3
chr19_+_8429031 0.40 ENST00000301455.2
ENST00000541807.1
ENST00000393962.2
angiopoietin-like 4
chr12_+_119772502 0.39 ENST00000536742.1
ENST00000327554.2
coiled-coil domain containing 60
chr3_+_44916098 0.39 ENST00000296125.4
transglutaminase 4
chr21_+_39644172 0.39 ENST00000398932.1
potassium inwardly-rectifying channel, subfamily J, member 15
chr6_+_46620705 0.39 ENST00000452689.2
solute carrier family 25, member 27
chr22_-_36556821 0.38 ENST00000531095.1
ENST00000397293.2
ENST00000349314.2
apolipoprotein L, 3
chr6_+_32937083 0.38 ENST00000456339.1
bromodomain containing 2
chr19_-_10628117 0.38 ENST00000333430.4
sphingosine-1-phosphate receptor 5
chr9_+_71736177 0.38 ENST00000606364.1
ENST00000453658.2
tight junction protein 2
chr14_+_101293687 0.37 ENST00000455286.1
maternally expressed 3 (non-protein coding)
chr14_+_75988768 0.36 ENST00000286639.6
basic leucine zipper transcription factor, ATF-like
chr20_-_62168672 0.36 ENST00000217185.2
protein tyrosine kinase 6
chr21_+_39644214 0.36 ENST00000438657.1
potassium inwardly-rectifying channel, subfamily J, member 15
chr1_-_109584716 0.36 ENST00000531337.1
ENST00000529074.1
ENST00000369965.4
WD repeat domain 47
chr17_+_4901199 0.36 ENST00000320785.5
ENST00000574165.1
kinesin family member 1C
chrX_+_37208540 0.35 ENST00000466533.1
ENST00000542554.1
ENST00000543642.1
ENST00000484460.1
ENST00000449135.2
ENST00000463135.1
ENST00000465127.1
proline rich Gla (G-carboxyglutamic acid) 1
Uncharacterized protein; cDNA FLJ59144, highly similar to Tetraspanin-7
chr20_+_43803517 0.35 ENST00000243924.3
peptidase inhibitor 3, skin-derived
chr6_-_10419871 0.34 ENST00000319516.4
transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
chr3_+_156393349 0.34 ENST00000473702.1
TCDD-inducible poly(ADP-ribose) polymerase
chr3_-_122233723 0.34 ENST00000493510.1
ENST00000344337.6
ENST00000476916.1
ENST00000465882.1
karyopherin alpha 1 (importin alpha 5)
chr19_-_14629224 0.34 ENST00000254322.2
DnaJ (Hsp40) homolog, subfamily B, member 1
chr2_-_238499131 0.33 ENST00000538644.1
RAB17, member RAS oncogene family
chr3_-_183735731 0.33 ENST00000334444.6
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
chr3_+_38032216 0.33 ENST00000416303.1
villin-like
chr20_+_37230511 0.33 ENST00000373345.4
Rho GTPase activating protein 40
chr6_-_29648887 0.32 ENST00000376883.1
ZFP57 zinc finger protein
chr19_+_56905024 0.32 ENST00000591172.1
ENST00000589888.1
ENST00000587979.1
ENST00000585659.1
ENST00000593109.1
ZNF582 antisense RNA 1 (head to head)
chr12_-_10826612 0.32 ENST00000535345.1
ENST00000542562.1
serine/threonine/tyrosine kinase 1
chr3_+_42977846 0.32 ENST00000383748.4
KRAB box domain containing 1
chr22_-_38699003 0.32 ENST00000451964.1
casein kinase 1, epsilon
chrX_-_7895755 0.31 ENST00000444736.1
ENST00000537427.1
ENST00000442940.1
patatin-like phospholipase domain containing 4
chr1_-_109584768 0.31 ENST00000357672.3
WD repeat domain 47
chr19_-_49567124 0.31 ENST00000301411.3
neurotrophin 4
chr18_+_14748194 0.31 ENST00000358984.4
ankyrin repeat domain 30B
chr1_-_27709816 0.31 ENST00000374030.1
CD164 sialomucin-like 2
chr7_-_150020750 0.31 ENST00000539352.1
ARP3 actin-related protein 3 homolog C (yeast)
chr14_+_71165292 0.30 ENST00000553682.1
RP6-65G23.1
chr1_-_116926718 0.30 ENST00000598661.1
Uncharacterized protein
chr7_+_157129660 0.30 ENST00000429029.2
ENST00000262177.4
ENST00000417758.1
ENST00000452797.2
ENST00000443280.1
DnaJ (Hsp40) homolog, subfamily B, member 6
chr19_-_2151523 0.30 ENST00000350812.6
ENST00000355272.6
ENST00000356926.4
ENST00000345016.5
adaptor-related protein complex 3, delta 1 subunit
chr14_-_21493123 0.29 ENST00000556147.1
ENST00000554489.1
ENST00000555657.1
ENST00000557274.1
ENST00000555158.1
ENST00000554833.1
ENST00000555384.1
ENST00000556420.1
ENST00000554893.1
ENST00000553503.1
ENST00000555733.1
ENST00000553867.1
ENST00000397856.3
ENST00000397855.3
ENST00000556008.1
ENST00000557182.1
ENST00000554483.1
ENST00000556688.1
ENST00000397853.3
ENST00000556329.2
ENST00000554143.1
ENST00000397851.2
ENST00000555142.1
ENST00000557676.1
ENST00000556924.1
NDRG family member 2
chr11_+_64323098 0.29 ENST00000301891.4
solute carrier family 22 (organic anion/urate transporter), member 11
chr5_+_149887672 0.29 ENST00000261797.6
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
chr21_+_42733870 0.29 ENST00000330714.3
ENST00000436410.1
ENST00000435611.1
myxovirus (influenza virus) resistance 2 (mouse)
chr9_+_470288 0.29 ENST00000382303.1
KN motif and ankyrin repeat domains 1
chr12_-_47219733 0.29 ENST00000547477.1
ENST00000447411.1
ENST00000266579.4
solute carrier family 38, member 4
chr11_+_33563821 0.28 ENST00000321505.4
ENST00000265654.5
ENST00000389726.3
KIAA1549-like
chrX_+_150866779 0.28 ENST00000370353.3
proline rich Gla (G-carboxyglutamic acid) 3 (transmembrane)
chr1_-_47082495 0.28 ENST00000545730.1
ENST00000531769.1
ENST00000319928.3
MAP kinase interacting serine/threonine kinase 1
MOB kinase activator 3C
chr8_-_8318847 0.28 ENST00000521218.1
CTA-398F10.2
chr2_-_9143786 0.28 ENST00000462696.1
ENST00000305997.3
membrane bound O-acyltransferase domain containing 2
chr6_-_46620522 0.28 ENST00000275016.2
cytochrome P450, family 39, subfamily A, polypeptide 1
chr7_-_150020814 0.28 ENST00000477871.1
ARP3 actin-related protein 3 homolog C (yeast)
chr2_+_28718921 0.28 ENST00000327757.5
ENST00000422425.2
ENST00000404858.1
phospholipase B1
chr20_-_18038521 0.27 ENST00000278780.6
ovo-like zinc finger 2
chr9_+_72658490 0.27 ENST00000377182.4
MAM domain containing 2
chr4_+_57396766 0.27 ENST00000512175.2
theg spermatid protein-like
chr11_+_65851443 0.27 ENST00000533756.1
phosphofurin acidic cluster sorting protein 1
chr3_-_18487057 0.27 ENST00000415069.1
SATB homeobox 1
chr4_+_119200215 0.26 ENST00000602573.1
small nucleolar RNA host gene 8 (non-protein coding)
chr4_+_166300084 0.26 ENST00000402744.4
carboxypeptidase E
chr19_-_14628234 0.26 ENST00000595139.1
DnaJ (Hsp40) homolog, subfamily B, member 1
chr6_+_29910301 0.26 ENST00000376809.5
ENST00000376802.2
major histocompatibility complex, class I, A
chr10_+_24528108 0.26 ENST00000438429.1
KIAA1217
chr12_-_10875831 0.26 ENST00000279550.7
ENST00000228251.4
Y box binding protein 3
chr11_+_33563618 0.26 ENST00000526400.1
KIAA1549-like
chr10_-_90611566 0.26 ENST00000371930.4
ankyrin repeat domain 22
chr11_-_111782484 0.26 ENST00000533971.1
crystallin, alpha B
chr20_+_58203664 0.26 ENST00000541461.1
phosphatase and actin regulator 3
chr3_+_42947600 0.26 ENST00000328199.6
ENST00000541208.1
zinc finger protein 662
chr20_+_1875378 0.26 ENST00000356025.3
signal-regulatory protein alpha
chr7_-_139763521 0.25 ENST00000263549.3
poly (ADP-ribose) polymerase family, member 12
chr10_+_15001430 0.25 ENST00000407572.1
meiosis/spermiogenesis associated 1
chr2_+_220144052 0.25 ENST00000425450.1
ENST00000392086.4
ENST00000421532.1
DnaJ (Hsp40) homolog, subfamily B, member 2
chr17_-_43138357 0.25 ENST00000342350.5
dephospho-CoA kinase domain containing
chr11_-_914812 0.25 ENST00000533059.1
chitinase domain containing 1
chr19_-_56904799 0.25 ENST00000589895.1
ENST00000589143.1
ENST00000301310.4
ENST00000586929.1
zinc finger protein 582
chr19_-_44952635 0.25 ENST00000592308.1
ENST00000588931.1
ENST00000291187.4
zinc finger protein 229
chr11_-_134123142 0.25 ENST00000392595.2
ENST00000341541.3
ENST00000352327.5
ENST00000392594.3
thymocyte nuclear protein 1
chr18_-_32870148 0.25 ENST00000589178.1
ENST00000333206.5
ENST00000592278.1
ENST00000592211.1
ENST00000420878.3
ENST00000383091.2
ENST00000586922.2
zinc finger and SCAN domain containing 30
RP11-158H5.7
chr11_-_33744256 0.24 ENST00000415002.2
ENST00000437761.2
ENST00000445143.2
CD59 molecule, complement regulatory protein
chr13_-_79979919 0.24 ENST00000267229.7
RNA binding motif protein 26
chr13_-_79979952 0.24 ENST00000438724.1
RNA binding motif protein 26
chr19_-_12444519 0.24 ENST00000595977.1
zinc finger protein 563
chr2_+_220143989 0.24 ENST00000336576.5
DnaJ (Hsp40) homolog, subfamily B, member 2
chr6_+_10521574 0.24 ENST00000495262.1
glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
chrX_+_37208521 0.24 ENST00000378628.4
proline rich Gla (G-carboxyglutamic acid) 1
chr3_-_59035673 0.24 ENST00000491845.1
ENST00000472469.1
ENST00000471288.1
ENST00000295966.7
chromosome 3 open reading frame 67
chr1_-_236030216 0.24 ENST00000389794.3
ENST00000389793.2
lysosomal trafficking regulator
chr11_-_88070896 0.24 ENST00000529974.1
ENST00000527018.1
cathepsin C
chr12_-_123011536 0.24 ENST00000331738.7
ENST00000354654.2
arginine/serine-rich coiled-coil 2
chr9_+_109685630 0.23 ENST00000451160.2
Uncharacterized protein
chr1_-_27709793 0.23 ENST00000374027.3
ENST00000374025.3
CD164 sialomucin-like 2
chr1_+_152957707 0.23 ENST00000368762.1
small proline-rich protein 1A
chr6_-_112081113 0.23 ENST00000517419.1
FYN oncogene related to SRC, FGR, YES
chr3_+_52720187 0.23 ENST00000474423.1
guanine nucleotide binding protein-like 3 (nucleolar)
chr11_-_105010320 0.23 ENST00000532895.1
ENST00000530950.1
caspase recruitment domain family, member 18
chrX_-_152939252 0.23 ENST00000340888.3
pregnancy up-regulated nonubiquitous CaM kinase
chr2_+_220144168 0.23 ENST00000392087.2
ENST00000442681.1
ENST00000439026.1
DnaJ (Hsp40) homolog, subfamily B, member 2
chr7_+_2393714 0.23 ENST00000431643.1
eukaryotic translation initiation factor 3, subunit B
chr22_+_41253080 0.23 ENST00000541156.1
ENST00000414396.1
ENST00000357137.4
X-prolyl aminopeptidase (aminopeptidase P) 3, putative
chr7_+_116451100 0.22 ENST00000464223.1
ENST00000484325.1
capping protein (actin filament) muscle Z-line, alpha 2
chr6_-_116601044 0.22 ENST00000368608.3
TSPY-like 1
chr9_+_19408999 0.22 ENST00000340967.2
alkaline ceramidase 2
chr4_-_159644507 0.22 ENST00000307720.3
peptidylprolyl isomerase D
chr12_-_76425368 0.22 ENST00000602540.1
pleckstrin homology-like domain, family A, member 1
chr6_-_38607673 0.22 ENST00000481247.1
BTB (POZ) domain containing 9
chr17_+_8339189 0.22 ENST00000585098.1
ENST00000380025.4
ENST00000402554.3
ENST00000584866.1
ENST00000582490.1
nudE neurodevelopment protein 1-like 1
chr6_-_131949200 0.22 ENST00000539158.1
ENST00000368058.1
mediator complex subunit 23
chr2_+_231577532 0.22 ENST00000258418.5
calcium binding protein 39
chr19_+_3762703 0.22 ENST00000589174.1
mitochondrial ribosomal protein L54
chr13_-_79980315 0.22 ENST00000438737.2
RNA binding motif protein 26
chr1_-_10856694 0.22 ENST00000377022.3
ENST00000344008.5
castor zinc finger 1
chr3_+_32433363 0.22 ENST00000465248.1
CKLF-like MARVEL transmembrane domain containing 7
chr6_-_160210604 0.21 ENST00000420894.2
ENST00000539756.1
ENST00000544255.1
t-complex 1
chr1_-_149982624 0.21 ENST00000417191.1
ENST00000369135.4
OTU domain containing 7B
chr7_+_70229899 0.21 ENST00000443672.1
autism susceptibility candidate 2
chr3_-_183735651 0.21 ENST00000427120.2
ENST00000392579.2
ENST00000382494.2
ENST00000446941.2
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
chr1_-_201390846 0.21 ENST00000367312.1
ENST00000555340.2
ENST00000361379.4
troponin I type 1 (skeletal, slow)
chr4_+_90032651 0.21 ENST00000603357.1
RP11-84C13.1
chr5_-_171615315 0.21 ENST00000176763.5
serine/threonine kinase 10
chr6_+_32936353 0.21 ENST00000374825.4
bromodomain containing 2
chr11_-_33744487 0.21 ENST00000426650.2
CD59 molecule, complement regulatory protein
chrX_-_152989499 0.21 ENST00000423827.1
B-cell receptor-associated protein 31
chr17_-_39928501 0.21 ENST00000420370.1
junction plakoglobin
chr2_+_85360499 0.21 ENST00000282111.3
transcription factor 7-like 1 (T-cell specific, HMG-box)
chr1_-_68698197 0.21 ENST00000370973.2
ENST00000370971.1
wntless Wnt ligand secretion mediator
chr22_+_38453207 0.21 ENST00000404072.3
ENST00000424694.1
protein interacting with PRKCA 1
chr5_+_14664762 0.21 ENST00000284274.4
family with sequence similarity 105, member B
chr1_+_47489240 0.20 ENST00000371901.3
cytochrome P450, family 4, subfamily X, polypeptide 1
chr2_+_113816685 0.20 ENST00000393200.2
interleukin 36 receptor antagonist
chr3_-_195603566 0.20 ENST00000424563.1
ENST00000411741.1
tyrosine kinase, non-receptor, 2
chrX_+_64887512 0.20 ENST00000360270.5
moesin
chr17_-_76123101 0.20 ENST00000392467.3
transmembrane channel-like 6
chr9_+_123970052 0.20 ENST00000373823.3
gelsolin
chr21_-_46221684 0.20 ENST00000330942.5
ubiquitin-conjugating enzyme E2G 2
chr22_+_29664241 0.20 ENST00000436425.1
ENST00000447973.1
EWS RNA-binding protein 1

Network of associatons between targets according to the STRING database.

First level regulatory network of HSF1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:0051562 negative regulation of mitochondrial calcium ion concentration(GO:0051562)
0.2 1.0 GO:0050717 positive regulation of interleukin-1 alpha secretion(GO:0050717)
0.2 0.6 GO:0060545 positive regulation of necroptotic process(GO:0060545)
0.2 1.4 GO:0071603 endothelial cell-cell adhesion(GO:0071603)
0.2 0.6 GO:2000297 negative regulation of synapse maturation(GO:2000297)
0.2 0.6 GO:0002581 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581)
0.2 1.1 GO:0002803 positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antimicrobial humoral response(GO:0002760) positive regulation of antibacterial peptide production(GO:0002803)
0.2 0.5 GO:0002894 positive regulation of type IIa hypersensitivity(GO:0001798) positive regulation of type II hypersensitivity(GO:0002894)
0.2 0.5 GO:0048633 negative regulation of auditory receptor cell differentiation(GO:0045608) positive regulation of skeletal muscle tissue growth(GO:0048633)
0.2 0.5 GO:0097195 pilomotor reflex(GO:0097195)
0.1 0.7 GO:1903644 regulation of chaperone-mediated protein folding(GO:1903644)
0.1 2.5 GO:0043587 tongue morphogenesis(GO:0043587)
0.1 1.2 GO:0060715 syncytiotrophoblast cell differentiation involved in labyrinthine layer development(GO:0060715)
0.1 0.4 GO:0032707 negative regulation of interleukin-23 production(GO:0032707)
0.1 0.6 GO:0038098 sequestering of BMP from receptor via BMP binding(GO:0038098)
0.1 0.5 GO:0001971 negative regulation of activation of membrane attack complex(GO:0001971)
0.1 0.8 GO:1903575 cornified envelope assembly(GO:1903575)
0.1 0.3 GO:0002337 B-1a B cell differentiation(GO:0002337)
0.1 0.3 GO:0008052 sensory organ boundary specification(GO:0008052) formation of organ boundary(GO:0010160) taste bud development(GO:0061193)
0.1 0.4 GO:0042000 translocation of peptides or proteins into host(GO:0042000) translocation of peptides or proteins into host cell cytoplasm(GO:0044053) translocation of molecules into host(GO:0044417) translocation of peptides or proteins into other organism involved in symbiotic interaction(GO:0051808) translocation of molecules into other organism involved in symbiotic interaction(GO:0051836)
0.1 0.3 GO:0048003 synaptic vesicle recycling via endosome(GO:0036466) antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003) antigen processing and presentation, exogenous lipid antigen via MHC class Ib(GO:0048007)
0.1 0.3 GO:2000393 negative regulation of lamellipodium morphogenesis(GO:2000393)
0.1 3.4 GO:0031581 hemidesmosome assembly(GO:0031581)
0.1 0.4 GO:1904000 positive regulation of eating behavior(GO:1904000)
0.1 0.4 GO:0070370 heat acclimation(GO:0010286) cellular heat acclimation(GO:0070370)
0.1 0.6 GO:1900242 regulation of synaptic vesicle endocytosis(GO:1900242)
0.1 0.6 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
0.1 0.3 GO:0030070 insulin processing(GO:0030070)
0.1 0.4 GO:0002415 immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor(GO:0002415)
0.1 1.2 GO:0032119 sequestering of zinc ion(GO:0032119)
0.1 0.2 GO:0033364 mast cell secretory granule organization(GO:0033364)
0.1 0.5 GO:0019355 nicotinamide nucleotide biosynthetic process from aspartate(GO:0019355) 'de novo' NAD biosynthetic process from aspartate(GO:0034628)
0.1 0.2 GO:2000687 negative regulation of rubidium ion transport(GO:2000681) negative regulation of rubidium ion transmembrane transporter activity(GO:2000687)
0.1 0.6 GO:1903265 positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
0.1 0.3 GO:0021557 optic cup structural organization(GO:0003409) oculomotor nerve development(GO:0021557) oculomotor nerve morphogenesis(GO:0021622) oculomotor nerve formation(GO:0021623)
0.1 0.2 GO:0040009 regulation of growth rate(GO:0040009)
0.1 0.4 GO:1990481 mRNA pseudouridine synthesis(GO:1990481)
0.1 0.2 GO:0006478 peptidyl-tyrosine sulfation(GO:0006478)
0.1 0.4 GO:0015798 myo-inositol transport(GO:0015798)
0.1 0.6 GO:0071492 cellular response to UV-A(GO:0071492)
0.1 0.4 GO:0006196 AMP catabolic process(GO:0006196)
0.1 0.2 GO:0006433 glutamyl-tRNA aminoacylation(GO:0006424) prolyl-tRNA aminoacylation(GO:0006433)
0.1 0.4 GO:1904154 positive regulation of retrograde protein transport, ER to cytosol(GO:1904154)
0.1 0.3 GO:0030573 bile acid catabolic process(GO:0030573)
0.1 0.7 GO:0060052 neurofilament cytoskeleton organization(GO:0060052)
0.1 0.4 GO:2000048 negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.1 0.2 GO:0086054 atrial ventricular junction remodeling(GO:0003294) atrial cardiac muscle cell to AV node cell communication by electrical coupling(GO:0086044) bundle of His cell to Purkinje myocyte communication by electrical coupling(GO:0086054) Purkinje myocyte to ventricular cardiac muscle cell communication by electrical coupling(GO:0086055) regulation of Purkinje myocyte action potential(GO:0098906) vasomotion(GO:1990029)
0.1 0.2 GO:0098582 innate vocalization behavior(GO:0098582)
0.1 0.3 GO:0090285 negative regulation of protein glycosylation in Golgi(GO:0090285)
0.1 0.2 GO:0035750 protein localization to myelin sheath abaxonal region(GO:0035750)
0.1 0.2 GO:0061357 positive regulation of Wnt protein secretion(GO:0061357)
0.1 0.9 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.1 0.1 GO:0046086 adenosine biosynthetic process(GO:0046086)
0.0 0.2 GO:0001835 blastocyst hatching(GO:0001835) hatching(GO:0035188) organism emergence from protective structure(GO:0071684)
0.0 0.4 GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
0.0 0.1 GO:0032730 positive regulation of interleukin-1 alpha production(GO:0032730)
0.0 0.3 GO:0060214 endocardium formation(GO:0060214)
0.0 0.2 GO:0048294 negative regulation of isotype switching to IgE isotypes(GO:0048294)
0.0 0.7 GO:0070970 interleukin-2 secretion(GO:0070970)
0.0 0.1 GO:0031247 actin rod assembly(GO:0031247)
0.0 0.9 GO:0007021 tubulin complex assembly(GO:0007021)
0.0 0.2 GO:0022614 membrane to membrane docking(GO:0022614)
0.0 0.1 GO:0051466 corticotropin-releasing hormone secretion(GO:0043396) regulation of corticotropin-releasing hormone secretion(GO:0043397) positive regulation of corticotropin-releasing hormone secretion(GO:0051466)
0.0 0.2 GO:1903906 plasma membrane raft distribution(GO:0044855) plasma membrane raft localization(GO:0044856) plasma membrane raft polarization(GO:0044858) regulation of plasma membrane raft polarization(GO:1903906)
0.0 0.4 GO:0051005 negative regulation of lipoprotein lipase activity(GO:0051005)
0.0 0.4 GO:0071847 TNFSF11-mediated signaling pathway(GO:0071847)
0.0 0.1 GO:0006667 sphinganine metabolic process(GO:0006667)
0.0 0.2 GO:0044501 modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032)
0.0 1.2 GO:0071294 cellular response to zinc ion(GO:0071294)
0.0 0.2 GO:0036438 maintenance of lens transparency(GO:0036438)
0.0 0.1 GO:0045715 negative regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045715)
0.0 0.1 GO:0045210 FasL biosynthetic process(GO:0045210)
0.0 0.2 GO:0071947 protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
0.0 0.2 GO:1902766 skeletal muscle satellite cell migration(GO:1902766)
0.0 0.0 GO:0002886 regulation of myeloid leukocyte mediated immunity(GO:0002886)
0.0 0.2 GO:0072660 maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.0 0.1 GO:0070676 intralumenal vesicle formation(GO:0070676)
0.0 0.3 GO:0051533 positive regulation of NFAT protein import into nucleus(GO:0051533)
0.0 0.1 GO:0035720 intraciliary anterograde transport(GO:0035720)
0.0 0.3 GO:0006477 protein sulfation(GO:0006477)
0.0 0.2 GO:0097411 hypoxia-inducible factor-1alpha signaling pathway(GO:0097411)
0.0 0.1 GO:0035606 peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
0.0 0.1 GO:0072308 negative regulation by virus of viral protein levels in host cell(GO:0046725) negative regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072308)
0.0 0.1 GO:0019082 viral protein processing(GO:0019082) regulation of nerve growth factor production(GO:0032903) negative regulation of nerve growth factor production(GO:0032904) dibasic protein processing(GO:0090472)
0.0 0.1 GO:0098972 dendritic transport of mitochondrion(GO:0098939) anterograde dendritic transport of mitochondrion(GO:0098972)
0.0 0.2 GO:0035234 ectopic germ cell programmed cell death(GO:0035234)
0.0 0.1 GO:1900226 negative regulation of NLRP3 inflammasome complex assembly(GO:1900226)
0.0 0.2 GO:0032907 transforming growth factor beta3 production(GO:0032907) regulation of transforming growth factor beta3 production(GO:0032910) positive regulation of transforming growth factor beta3 production(GO:0032916) negative regulation of lung blood pressure(GO:0061767)
0.0 0.0 GO:0046668 regulation of retinal cell programmed cell death(GO:0046668)
0.0 0.3 GO:0015747 urate transport(GO:0015747)
0.0 0.3 GO:0002480 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent(GO:0002480)
0.0 0.2 GO:1902714 negative regulation of interferon-gamma secretion(GO:1902714)
0.0 0.8 GO:0060575 intestinal epithelial cell differentiation(GO:0060575)
0.0 0.3 GO:0035799 ureter maturation(GO:0035799)
0.0 0.3 GO:2000580 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.0 0.1 GO:0097212 lysosomal membrane organization(GO:0097212) negative regulation of hydrogen peroxide catabolic process(GO:2000296) regulation of oxygen metabolic process(GO:2000374)
0.0 0.1 GO:0046947 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.0 0.3 GO:1902219 negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress(GO:1902219)
0.0 0.1 GO:0015855 pyrimidine nucleobase transport(GO:0015855) purine nucleobase transmembrane transport(GO:1904823)
0.0 0.1 GO:0035880 embryonic nail plate morphogenesis(GO:0035880)
0.0 0.1 GO:1904383 response to sodium phosphate(GO:1904383)
0.0 0.2 GO:0075525 viral translational termination-reinitiation(GO:0075525)
0.0 0.4 GO:0030213 hyaluronan biosynthetic process(GO:0030213)
0.0 0.2 GO:0030263 apoptotic chromosome condensation(GO:0030263)
0.0 0.0 GO:1904349 regulation of small intestine smooth muscle contraction(GO:1904347) positive regulation of small intestine smooth muscle contraction(GO:1904349) small intestine smooth muscle contraction(GO:1990770)
0.0 0.1 GO:0040037 negative regulation of fibroblast growth factor receptor signaling pathway(GO:0040037)
0.0 0.2 GO:0048050 post-embryonic eye morphogenesis(GO:0048050)
0.0 0.1 GO:0038178 complement component C5a signaling pathway(GO:0038178)
0.0 0.1 GO:2001034 positive regulation of double-strand break repair via nonhomologous end joining(GO:2001034)
0.0 0.2 GO:2000781 positive regulation of double-strand break repair(GO:2000781)
0.0 0.2 GO:0070131 positive regulation of mitochondrial translation(GO:0070131)
0.0 0.1 GO:1901907 diadenosine polyphosphate catabolic process(GO:0015961) diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.0 0.3 GO:0033235 positive regulation of protein sumoylation(GO:0033235)
0.0 0.2 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.0 0.2 GO:0050713 negative regulation of interleukin-1 beta secretion(GO:0050713)
0.0 0.1 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.0 0.1 GO:0043686 co-translational protein modification(GO:0043686)
0.0 0.1 GO:1901526 positive regulation of macromitophagy(GO:1901526) positive regulation of mitophagy in response to mitochondrial depolarization(GO:1904925)
0.0 0.2 GO:0002349 histamine production involved in inflammatory response(GO:0002349) histamine secretion involved in inflammatory response(GO:0002441) histamine secretion by mast cell(GO:0002553)
0.0 0.3 GO:0090360 platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
0.0 0.1 GO:0010710 regulation of collagen catabolic process(GO:0010710)
0.0 0.1 GO:0000711 meiotic DNA repair synthesis(GO:0000711)
0.0 0.2 GO:0002084 protein depalmitoylation(GO:0002084)
0.0 0.1 GO:0031642 negative regulation of myelination(GO:0031642)
0.0 0.2 GO:0070862 negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.0 0.1 GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.0 0.1 GO:0050689 negative regulation of defense response to virus by host(GO:0050689)
0.0 0.2 GO:1902951 negative regulation of dendritic spine maintenance(GO:1902951)
0.0 0.1 GO:0050712 negative regulation of interleukin-1 alpha production(GO:0032690) negative regulation of interleukin-1 alpha secretion(GO:0050712)
0.0 0.0 GO:2000619 negative regulation of histone H4-K16 acetylation(GO:2000619)
0.0 0.2 GO:0032057 negative regulation of translational initiation in response to stress(GO:0032057)
0.0 0.2 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
0.0 0.7 GO:0070306 lens fiber cell differentiation(GO:0070306)
0.0 0.1 GO:0002296 T-helper 1 cell lineage commitment(GO:0002296)
0.0 0.0 GO:0006579 amino-acid betaine catabolic process(GO:0006579)
0.0 1.0 GO:1902230 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902230)
0.0 0.3 GO:0003373 dynamin polymerization involved in membrane fission(GO:0003373) dynamin polymerization involved in mitochondrial fission(GO:0003374)
0.0 0.1 GO:0040032 post-embryonic body morphogenesis(GO:0040032)
0.0 0.1 GO:0019236 response to pheromone(GO:0019236)
0.0 0.1 GO:1903300 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.0 0.1 GO:0045085 negative regulation of interleukin-2 biosynthetic process(GO:0045085)
0.0 0.4 GO:0043373 T-helper cell lineage commitment(GO:0002295) CD4-positive, alpha-beta T cell lineage commitment(GO:0043373) T-helper 17 cell lineage commitment(GO:0072540)
0.0 0.8 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.0 0.0 GO:0016256 N-glycan processing to lysosome(GO:0016256)
0.0 0.0 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
0.0 0.2 GO:0002051 osteoblast fate commitment(GO:0002051)
0.0 0.1 GO:1900535 medium-chain fatty-acyl-CoA catabolic process(GO:0036114) long-chain fatty-acyl-CoA catabolic process(GO:0036116) palmitic acid metabolic process(GO:1900533) palmitic acid biosynthetic process(GO:1900535)
0.0 0.1 GO:0071374 cellular response to parathyroid hormone stimulus(GO:0071374)
0.0 0.2 GO:0009249 protein lipoylation(GO:0009249)
0.0 0.0 GO:0002305 gamma-delta intraepithelial T cell differentiation(GO:0002304) CD8-positive, gamma-delta intraepithelial T cell differentiation(GO:0002305)
0.0 0.4 GO:0019054 modulation by virus of host process(GO:0019054)
0.0 0.1 GO:0001951 intestinal D-glucose absorption(GO:0001951)
0.0 0.4 GO:0007620 copulation(GO:0007620)
0.0 0.1 GO:0051413 response to cortisone(GO:0051413)
0.0 0.1 GO:2001013 epithelial cell proliferation involved in renal tubule morphogenesis(GO:2001013)
0.0 0.1 GO:0048254 snoRNA localization(GO:0048254)
0.0 0.2 GO:0007258 JUN phosphorylation(GO:0007258)
0.0 0.0 GO:1903660 negative regulation of complement-dependent cytotoxicity(GO:1903660)
0.0 0.2 GO:0001778 plasma membrane repair(GO:0001778)
0.0 0.5 GO:0036151 phosphatidylcholine acyl-chain remodeling(GO:0036151)
0.0 0.1 GO:0046085 adenosine metabolic process(GO:0046085)
0.0 0.1 GO:0060992 response to fungicide(GO:0060992)
0.0 0.1 GO:0071286 cellular response to magnesium ion(GO:0071286)
0.0 0.3 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.0 0.0 GO:0002232 leukocyte chemotaxis involved in inflammatory response(GO:0002232)
0.0 0.8 GO:0010107 potassium ion import(GO:0010107)
0.0 0.4 GO:0045730 respiratory burst(GO:0045730)
0.0 0.0 GO:0061386 closure of optic fissure(GO:0061386)
0.0 0.1 GO:0032482 Rab protein signal transduction(GO:0032482)
0.0 0.2 GO:0046951 ketone body biosynthetic process(GO:0046951)
0.0 0.1 GO:0098881 exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967)
0.0 0.1 GO:0045084 positive regulation of interleukin-12 biosynthetic process(GO:0045084)
0.0 0.1 GO:0032790 ribosome disassembly(GO:0032790)
0.0 1.1 GO:0071300 cellular response to retinoic acid(GO:0071300)
0.0 0.3 GO:2000052 positive regulation of non-canonical Wnt signaling pathway(GO:2000052)
0.0 0.2 GO:0033227 dsRNA transport(GO:0033227)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.4 GO:0071665 gamma-catenin-TCF7L2 complex(GO:0071665)
0.2 2.1 GO:0097169 AIM2 inflammasome complex(GO:0097169)
0.2 1.1 GO:0097209 epidermal lamellar body(GO:0097209)
0.1 0.7 GO:0060053 neurofilament cytoskeleton(GO:0060053)
0.1 0.4 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.1 1.2 GO:0005610 laminin-5 complex(GO:0005610)
0.1 0.6 GO:0034678 integrin alpha8-beta1 complex(GO:0034678)
0.1 0.4 GO:0005784 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.1 4.7 GO:0045095 keratin filament(GO:0045095)
0.0 0.9 GO:0097512 cardiac myofibril(GO:0097512)
0.0 1.3 GO:0005922 connexon complex(GO:0005922)
0.0 0.5 GO:0032010 phagolysosome(GO:0032010)
0.0 0.2 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.0 0.9 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 0.1 GO:0071062 alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.0 0.2 GO:0070436 Grb2-EGFR complex(GO:0070436)
0.0 0.8 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 0.2 GO:0097452 GAIT complex(GO:0097452)
0.0 0.1 GO:1990796 photoreceptor cell terminal bouton(GO:1990796)
0.0 0.6 GO:0097342 ripoptosome(GO:0097342)
0.0 0.2 GO:0070545 PeBoW complex(GO:0070545)
0.0 0.4 GO:0030123 AP-3 adaptor complex(GO:0030123)
0.0 0.3 GO:0042611 MHC protein complex(GO:0042611)
0.0 0.2 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.0 0.2 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
0.0 0.7 GO:0042101 T cell receptor complex(GO:0042101)
0.0 0.3 GO:0002199 zona pellucida receptor complex(GO:0002199)
0.0 0.2 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.0 0.1 GO:0035339 SPOTS complex(GO:0035339)
0.0 0.1 GO:0097450 astrocyte end-foot(GO:0097450)
0.0 0.2 GO:0061574 ASAP complex(GO:0061574)
0.0 0.5 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.0 0.1 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.0 0.2 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.0 0.2 GO:0036128 CatSper complex(GO:0036128)
0.0 0.2 GO:0030478 actin cap(GO:0030478)
0.0 0.1 GO:0031417 NatC complex(GO:0031417)
0.0 0.1 GO:0071546 pi-body(GO:0071546)
0.0 2.1 GO:0045111 intermediate filament cytoskeleton(GO:0045111)
0.0 0.2 GO:0008290 F-actin capping protein complex(GO:0008290)
0.0 0.7 GO:0001533 cornified envelope(GO:0001533)
0.0 0.7 GO:0008180 COP9 signalosome(GO:0008180)
0.0 0.2 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.0 0.2 GO:0031931 TORC1 complex(GO:0031931)
0.0 0.1 GO:0005921 gap junction(GO:0005921)
0.0 0.0 GO:0001534 radial spoke(GO:0001534)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.4 GO:0005199 structural constituent of cell wall(GO:0005199)
0.2 1.2 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.2 0.7 GO:0070012 oligopeptidase activity(GO:0070012)
0.1 0.4 GO:0005365 myo-inositol transmembrane transporter activity(GO:0005365)
0.1 0.6 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.1 0.6 GO:0050253 retinyl-palmitate esterase activity(GO:0050253)
0.1 2.9 GO:0050700 CARD domain binding(GO:0050700)
0.1 0.3 GO:0071633 dihydroceramidase activity(GO:0071633)
0.1 0.5 GO:0000309 nicotinamide-nucleotide adenylyltransferase activity(GO:0000309)
0.1 1.4 GO:0005243 gap junction channel activity(GO:0005243)
0.1 0.2 GO:0001156 TFIIIC-class transcription factor binding(GO:0001156)
0.1 0.2 GO:0008476 protein-tyrosine sulfotransferase activity(GO:0008476)
0.1 1.1 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.1 0.2 GO:0004827 glutamate-tRNA ligase activity(GO:0004818) proline-tRNA ligase activity(GO:0004827)
0.1 0.6 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.1 0.2 GO:0009383 rRNA (cytosine-C5-)-methyltransferase activity(GO:0009383)
0.1 0.9 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.1 0.2 GO:0016608 growth hormone-releasing hormone activity(GO:0016608) ghrelin receptor binding(GO:0031768)
0.1 0.6 GO:0016015 morphogen activity(GO:0016015)
0.1 0.9 GO:0032395 MHC class II receptor activity(GO:0032395)
0.1 2.5 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.2 GO:0003858 3-hydroxybutyrate dehydrogenase activity(GO:0003858)
0.0 0.6 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 0.1 GO:0031731 CCR6 chemokine receptor binding(GO:0031731)
0.0 0.3 GO:0005166 neurotrophin p75 receptor binding(GO:0005166)
0.0 0.2 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.0 0.3 GO:0050119 N-acetylglucosamine deacetylase activity(GO:0050119)
0.0 0.4 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.1 GO:0050146 nucleoside phosphotransferase activity(GO:0050146)
0.0 0.2 GO:0005152 interleukin-1 receptor antagonist activity(GO:0005152)
0.0 0.4 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.0 0.1 GO:0004618 phosphoglycerate kinase activity(GO:0004618)
0.0 0.9 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.1 GO:0015389 pyrimidine- and adenine-specific:sodium symporter activity(GO:0015389)
0.0 0.2 GO:0023024 MHC class I protein complex binding(GO:0023024)
0.0 0.2 GO:0032564 adenyl deoxyribonucleotide binding(GO:0032558) dATP binding(GO:0032564)
0.0 0.7 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 0.2 GO:0050659 N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase activity(GO:0050659)
0.0 0.1 GO:0030272 5-formyltetrahydrofolate cyclo-ligase activity(GO:0030272)
0.0 0.2 GO:0052836 inositol 5-diphosphate pentakisphosphate 5-kinase activity(GO:0052836) inositol diphosphate tetrakisphosphate kinase activity(GO:0052839)
0.0 3.7 GO:0097110 scaffold protein binding(GO:0097110)
0.0 0.8 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 0.1 GO:0000033 alpha-1,3-mannosyltransferase activity(GO:0000033)
0.0 0.8 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.0 0.1 GO:0035373 chondroitin sulfate proteoglycan binding(GO:0035373)
0.0 0.3 GO:0030881 beta-2-microglobulin binding(GO:0030881)
0.0 0.5 GO:0043225 anion transmembrane-transporting ATPase activity(GO:0043225)
0.0 0.4 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.2 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.4 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.2 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.0 0.4 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.2 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.0 0.3 GO:1901702 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.0 0.5 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 0.3 GO:0019960 C-X3-C chemokine binding(GO:0019960)
0.0 0.2 GO:0042610 CD8 receptor binding(GO:0042610)
0.0 0.2 GO:0051032 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.0 0.1 GO:0033823 procollagen-lysine 5-dioxygenase activity(GO:0008475) procollagen glucosyltransferase activity(GO:0033823) procollagen galactosyltransferase activity(GO:0050211)
0.0 0.1 GO:0047676 arachidonate-CoA ligase activity(GO:0047676)
0.0 0.4 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 0.4 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 0.1 GO:0004140 dephospho-CoA kinase activity(GO:0004140)
0.0 0.1 GO:0004878 complement component C5a receptor activity(GO:0004878)
0.0 0.3 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.0 0.3 GO:0008525 phosphatidylcholine transporter activity(GO:0008525)
0.0 0.2 GO:0008172 S-methyltransferase activity(GO:0008172)
0.0 0.1 GO:0000298 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432) inositol diphosphate tetrakisphosphate diphosphatase activity(GO:0052840) inositol bisdiphosphate tetrakisphosphate diphosphatase activity(GO:0052841) inositol diphosphate pentakisphosphate diphosphatase activity(GO:0052842) inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity(GO:0052843) inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity(GO:0052844) inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity(GO:0052845) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity(GO:0052846) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052847) inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052848)
0.0 0.1 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 0.3 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.0 0.3 GO:0031852 mu-type opioid receptor binding(GO:0031852)
0.0 0.6 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.2 GO:0003696 satellite DNA binding(GO:0003696)
0.0 0.1 GO:0046790 virion binding(GO:0046790)
0.0 0.3 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.0 0.2 GO:0004705 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 0.1 GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)
0.0 0.1 GO:0008241 peptidyl-dipeptidase activity(GO:0008241)
0.0 0.0 GO:0003870 5-aminolevulinate synthase activity(GO:0003870) N-succinyltransferase activity(GO:0016749)
0.0 0.2 GO:0031404 chloride ion binding(GO:0031404)
0.0 0.0 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.0 0.1 GO:0016402 pristanoyl-CoA oxidase activity(GO:0016402)
0.0 0.2 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.0 0.1 GO:0043891 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.0 0.0 GO:0016774 phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.0 0.1 GO:0016454 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.0 0.7 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.3 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.2 GO:0045159 myosin II binding(GO:0045159)
0.0 0.2 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.1 GO:0004910 interleukin-1, Type II, blocking receptor activity(GO:0004910)
0.0 0.5 GO:0001848 complement binding(GO:0001848)
0.0 3.8 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.5 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.0 GO:0017082 mineralocorticoid receptor activity(GO:0017082)
0.0 1.3 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.1 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.0 0.1 GO:0050544 arachidonic acid binding(GO:0050544)
0.0 0.0 GO:0031728 CCR3 chemokine receptor binding(GO:0031728)
0.0 0.0 GO:0046997 oxidoreductase activity, acting on the CH-NH group of donors, flavin as acceptor(GO:0046997)
0.0 0.1 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.0 0.3 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.0 0.0 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.0 0.0 GO:0046538 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.0 0.1 GO:0001094 TFIID-class transcription factor binding(GO:0001094)
0.0 0.1 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.0 0.1 GO:0046703 natural killer cell lectin-like receptor binding(GO:0046703)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.2 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 1.9 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 2.4 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 0.8 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 1.3 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.0 0.7 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 0.9 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 0.3 PID S1P S1P4 PATHWAY S1P4 pathway
0.0 1.1 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
0.0 0.8 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.0 0.4 PID IL27 PATHWAY IL27-mediated signaling events
0.0 0.3 ST INTERLEUKIN 4 PATHWAY Interleukin 4 (IL-4) Pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.1 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.1 1.3 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 0.8 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 0.5 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0 1.6 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.5 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 0.5 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
0.0 1.2 REACTOME DOWNSTREAM TCR SIGNALING Genes involved in Downstream TCR signaling
0.0 0.4 REACTOME TRAF6 MEDIATED INDUCTION OF TAK1 COMPLEX Genes involved in TRAF6 mediated induction of TAK1 complex
0.0 0.4 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 0.3 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0 0.5 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.0 0.4 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.0 0.5 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 0.4 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 0.2 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.0 1.0 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.0 0.3 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 0.3 REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI Genes involved in RIP-mediated NFkB activation via DAI
0.0 0.6 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.0 1.0 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.0 0.7 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 0.3 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.0 1.5 REACTOME CELL JUNCTION ORGANIZATION Genes involved in Cell junction organization
0.0 0.2 REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1 Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.0 0.1 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR