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SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for HSF2

Z-value: 0.80

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Transcription factors associated with HSF2

Gene Symbol Gene ID Gene Info
HSF2
ENSG00000025156.8 heat shock transcription factor 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HSF2hg19_v2_chr6_+_122720681_122720713-0.058.4e-01Click!

Activity profile of HSF2 motif

Sorted Z-values of HSF2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr16_+_55600580 1.80 ENST00000457326.2
CAPNS2
calpain, small subunit 2
chr17_-_39661849 1.44 ENST00000246635.3
ENST00000336861.3
ENST00000587544.1
ENST00000587435.1
KRT13
keratin 13
chr15_+_78556428 1.02 ENST00000394855.3
ENST00000489435.2
DNAJA4
DnaJ (Hsp40) homolog, subfamily A, member 4
chr17_-_39661947 0.95 ENST00000590425.1
KRT13
keratin 13
chr8_+_38261880 0.93 ENST00000527175.1
LETM2
leucine zipper-EF-hand containing transmembrane protein 2
chr15_-_81616446 0.91 ENST00000302824.6
STARD5
StAR-related lipid transfer (START) domain containing 5
chr12_-_10007448 0.89 ENST00000538152.1
CLEC2B
C-type lectin domain family 2, member B
chr10_+_135340859 0.88 ENST00000252945.3
ENST00000421586.1
ENST00000418356.1
CYP2E1
cytochrome P450, family 2, subfamily E, polypeptide 1
chr15_+_42651691 0.83 ENST00000357568.3
ENST00000349748.3
ENST00000318023.7
ENST00000397163.3
CAPN3
calpain 3, (p94)
chr2_-_219151487 0.75 ENST00000444881.1
TMBIM1
transmembrane BAX inhibitor motif containing 1
chr12_-_123011476 0.74 ENST00000528279.1
ENST00000344591.4
ENST00000526560.2
RSRC2
arginine/serine-rich coiled-coil 2
chr10_-_25010795 0.71 ENST00000416305.1
ENST00000376410.2
ARHGAP21
Rho GTPase activating protein 21
chr4_+_184427235 0.71 ENST00000412117.1
ENST00000434682.2
ING2
inhibitor of growth family, member 2
chr17_-_79817091 0.70 ENST00000570907.1
P4HB
prolyl 4-hydroxylase, beta polypeptide
chr4_-_153601136 0.66 ENST00000504064.1
ENST00000304385.3
TMEM154
transmembrane protein 154
chr15_+_78556809 0.63 ENST00000343789.3
ENST00000394852.3
DNAJA4
DnaJ (Hsp40) homolog, subfamily A, member 4
chr14_-_67859422 0.61 ENST00000556532.1
PLEK2
pleckstrin 2
chr6_+_149539767 0.57 ENST00000606202.1
ENST00000536230.1
ENST00000445901.1
TAB2
RP1-111D6.3
TGF-beta activated kinase 1/MAP3K7 binding protein 2
RP1-111D6.3
chr4_+_154387480 0.57 ENST00000409663.3
ENST00000440693.1
ENST00000409959.3
KIAA0922
KIAA0922
chrX_-_51239425 0.54 ENST00000375992.3
NUDT11
nudix (nucleoside diphosphate linked moiety X)-type motif 11
chrX_-_30993201 0.53 ENST00000288422.2
ENST00000378932.2
TAB3
TGF-beta activated kinase 1/MAP3K7 binding protein 3
chr19_-_14629224 0.52 ENST00000254322.2
DNAJB1
DnaJ (Hsp40) homolog, subfamily B, member 1
chr19_-_49567124 0.51 ENST00000301411.3
NTF4
neurotrophin 4
chr9_+_34989638 0.51 ENST00000453597.3
ENST00000335998.3
ENST00000312316.5
DNAJB5
DnaJ (Hsp40) homolog, subfamily B, member 5
chr3_+_177534653 0.50 ENST00000436078.1
RP11-91K9.1
RP11-91K9.1
chr15_+_96869165 0.47 ENST00000421109.2
NR2F2
nuclear receptor subfamily 2, group F, member 2
chr18_-_812231 0.46 ENST00000314574.4
YES1
v-yes-1 Yamaguchi sarcoma viral oncogene homolog 1
chr22_+_41253080 0.46 ENST00000541156.1
ENST00000414396.1
ENST00000357137.4
XPNPEP3
X-prolyl aminopeptidase (aminopeptidase P) 3, putative
chr11_-_82997420 0.45 ENST00000455220.2
ENST00000529689.1
CCDC90B
coiled-coil domain containing 90B
chr18_+_32173276 0.45 ENST00000591816.1
ENST00000588125.1
ENST00000598334.1
ENST00000588684.1
ENST00000554864.3
ENST00000399121.5
ENST00000595022.1
ENST00000269190.7
ENST00000399097.3
DTNA
dystrobrevin, alpha
chr20_+_33292507 0.44 ENST00000414082.1
TP53INP2
tumor protein p53 inducible nuclear protein 2
chrX_+_135230712 0.44 ENST00000535737.1
FHL1
four and a half LIM domains 1
chr4_-_159644507 0.43 ENST00000307720.3
PPID
peptidylprolyl isomerase D
chrX_+_135279179 0.42 ENST00000370676.3
FHL1
four and a half LIM domains 1
chr16_+_226658 0.41 ENST00000320868.5
ENST00000397797.1
HBA1
hemoglobin, alpha 1
chr12_+_11802753 0.41 ENST00000396373.4
ETV6
ets variant 6
chr6_+_42584847 0.41 ENST00000372883.3
UBR2
ubiquitin protein ligase E3 component n-recognin 2
chr5_+_148442844 0.40 ENST00000515519.1
CTC-529P8.1
CTC-529P8.1
chr19_-_14628645 0.40 ENST00000598235.1
DNAJB1
DnaJ (Hsp40) homolog, subfamily B, member 1
chr5_-_148442584 0.37 ENST00000394358.2
ENST00000512049.1
SH3TC2
SH3 domain and tetratricopeptide repeats 2
chr1_+_151171012 0.37 ENST00000349792.5
ENST00000409426.1
ENST00000441902.2
ENST00000368890.4
ENST00000424999.1
ENST00000368888.4
PIP5K1A
phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
chr19_+_19516561 0.37 ENST00000457895.2
GATAD2A
GATA zinc finger domain containing 2A
chrX_+_135278908 0.37 ENST00000539015.1
ENST00000370683.1
FHL1
four and a half LIM domains 1
chr2_+_162272605 0.36 ENST00000389554.3
TBR1
T-box, brain, 1
chr4_-_74088800 0.36 ENST00000509867.2
ANKRD17
ankyrin repeat domain 17
chr2_-_178128250 0.35 ENST00000448782.1
ENST00000446151.2
NFE2L2
nuclear factor, erythroid 2-like 2
chr14_-_23624511 0.35 ENST00000529705.2
SLC7A8
solute carrier family 7 (amino acid transporter light chain, L system), member 8
chr12_-_123011536 0.35 ENST00000331738.7
ENST00000354654.2
RSRC2
arginine/serine-rich coiled-coil 2
chr3_-_183735731 0.34 ENST00000334444.6
ABCC5
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
chr10_-_101673782 0.34 ENST00000422692.1
DNMBP
dynamin binding protein
chr4_-_151936416 0.33 ENST00000510413.1
ENST00000507224.1
LRBA
LPS-responsive vesicle trafficking, beach and anchor containing
chr4_+_123161120 0.33 ENST00000446180.1
KIAA1109
KIAA1109
chr19_-_49522727 0.32 ENST00000600007.1
CTB-60B18.10
CTB-60B18.10
chr17_-_71410794 0.31 ENST00000424778.1
SDK2
sidekick cell adhesion molecule 2
chr19_-_49560987 0.31 ENST00000596965.1
CGB7
chorionic gonadotropin, beta polypeptide 7
chr3_-_49131473 0.30 ENST00000430979.1
ENST00000357496.2
ENST00000437939.1
QRICH1
glutamine-rich 1
chr3_-_183735651 0.30 ENST00000427120.2
ENST00000392579.2
ENST00000382494.2
ENST00000446941.2
ABCC5
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
chr14_-_102553371 0.30 ENST00000553585.1
ENST00000216281.8
HSP90AA1
heat shock protein 90kDa alpha (cytosolic), class A member 1
chr5_-_148442687 0.29 ENST00000515425.1
SH3TC2
SH3 domain and tetratricopeptide repeats 2
chr15_-_93965805 0.29 ENST00000556708.1
RP11-164C12.2
RP11-164C12.2
chr5_+_148443049 0.29 ENST00000515304.1
ENST00000507318.1
CTC-529P8.1
CTC-529P8.1
chr1_-_67142710 0.29 ENST00000502413.2
AL139147.1
Uncharacterized protein
chr11_-_111781554 0.29 ENST00000526167.1
ENST00000528961.1
CRYAB
crystallin, alpha B
chr11_+_65769946 0.28 ENST00000533166.1
BANF1
barrier to autointegration factor 1
chr3_+_177545563 0.28 ENST00000434309.1
RP11-91K9.1
RP11-91K9.1
chr13_-_31736132 0.28 ENST00000429785.2
HSPH1
heat shock 105kDa/110kDa protein 1
chr14_+_93357749 0.27 ENST00000557689.1
RP11-862G15.1
RP11-862G15.1
chr3_-_49131013 0.27 ENST00000424300.1
QRICH1
glutamine-rich 1
chr4_-_22517620 0.26 ENST00000502482.1
ENST00000334304.5
GPR125
G protein-coupled receptor 125
chr7_+_18330035 0.26 ENST00000413509.2
HDAC9
histone deacetylase 9
chrX_-_152989499 0.26 ENST00000423827.1
BCAP31
B-cell receptor-associated protein 31
chr6_-_53213587 0.26 ENST00000542638.1
ENST00000370913.5
ENST00000541407.1
ELOVL5
ELOVL fatty acid elongase 5
chr2_-_178128199 0.26 ENST00000449627.1
NFE2L2
nuclear factor, erythroid 2-like 2
chr19_-_2085323 0.25 ENST00000591638.1
MOB3A
MOB kinase activator 3A
chr11_-_122932730 0.25 ENST00000532182.1
ENST00000524590.1
ENST00000528292.1
ENST00000533540.1
ENST00000525463.1
HSPA8
heat shock 70kDa protein 8
chr20_+_4666882 0.25 ENST00000379440.4
ENST00000430350.2
PRNP
prion protein
chr6_+_42531798 0.25 ENST00000372903.2
ENST00000372899.1
ENST00000372901.1
UBR2
ubiquitin protein ligase E3 component n-recognin 2
chr11_+_1855645 0.24 ENST00000381968.3
ENST00000381978.3
SYT8
synaptotagmin VIII
chr2_-_178128149 0.24 ENST00000423513.1
NFE2L2
nuclear factor, erythroid 2-like 2
chrX_+_51075658 0.24 ENST00000356450.2
NUDT10
nudix (nucleoside diphosphate linked moiety X)-type motif 10
chr15_-_70388943 0.24 ENST00000559048.1
ENST00000560939.1
ENST00000440567.3
ENST00000557907.1
ENST00000558379.1
ENST00000451782.2
ENST00000559929.1
TLE3
transducin-like enhancer of split 3 (E(sp1) homolog, Drosophila)
chr20_+_31755934 0.24 ENST00000354932.5
BPIFA2
BPI fold containing family A, member 2
chr6_-_138866823 0.23 ENST00000342260.5
NHSL1
NHS-like 1
chr6_-_155635583 0.23 ENST00000367166.4
TFB1M
transcription factor B1, mitochondrial
chr14_+_38091270 0.22 ENST00000553443.1
TTC6
tetratricopeptide repeat domain 6
chr20_+_33292068 0.22 ENST00000374810.3
ENST00000374809.2
ENST00000451665.1
TP53INP2
tumor protein p53 inducible nuclear protein 2
chr11_+_1856034 0.22 ENST00000341958.3
SYT8
synaptotagmin VIII
chr15_-_43785274 0.22 ENST00000413546.1
TP53BP1
tumor protein p53 binding protein 1
chr12_+_119616447 0.22 ENST00000281938.2
HSPB8
heat shock 22kDa protein 8
chr6_-_53213780 0.21 ENST00000304434.6
ENST00000370918.4
ELOVL5
ELOVL fatty acid elongase 5
chr16_+_4606347 0.21 ENST00000444310.4
C16orf96
chromosome 16 open reading frame 96
chr10_+_122216707 0.21 ENST00000427079.1
ENST00000541332.1
PPAPDC1A
phosphatidic acid phosphatase type 2 domain containing 1A
chr9_+_109685630 0.20 ENST00000451160.2
RP11-508N12.4
Uncharacterized protein
chr15_-_70388599 0.20 ENST00000560996.1
ENST00000558201.1
TLE3
transducin-like enhancer of split 3 (E(sp1) homolog, Drosophila)
chr19_-_49250054 0.20 ENST00000602105.1
ENST00000332955.2
IZUMO1
izumo sperm-egg fusion 1
chr8_+_145065705 0.19 ENST00000533044.1
GRINA
glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding)
chr13_-_20805109 0.19 ENST00000241124.6
GJB6
gap junction protein, beta 6, 30kDa
chr21_+_35445811 0.19 ENST00000399312.2
MRPS6
mitochondrial ribosomal protein S6
chr15_-_58357866 0.18 ENST00000537372.1
ALDH1A2
aldehyde dehydrogenase 1 family, member A2
chr2_+_17997763 0.18 ENST00000281047.3
MSGN1
mesogenin 1
chr1_-_6453426 0.18 ENST00000545482.1
ACOT7
acyl-CoA thioesterase 7
chr9_+_125795788 0.17 ENST00000373643.5
RABGAP1
RAB GTPase activating protein 1
chr2_-_122247879 0.17 ENST00000545861.1
CLASP1
cytoplasmic linker associated protein 1
chr6_-_31782813 0.17 ENST00000375654.4
HSPA1L
heat shock 70kDa protein 1-like
chr11_+_117063295 0.17 ENST00000525478.1
ENST00000532062.1
SIDT2
SID1 transmembrane family, member 2
chr2_+_202937972 0.17 ENST00000541917.1
ENST00000295844.3
AC079354.1
uncharacterized protein KIAA2012
chr17_+_41052808 0.17 ENST00000592383.1
ENST00000253801.2
ENST00000585489.1
G6PC
glucose-6-phosphatase, catalytic subunit
chr6_-_135375986 0.17 ENST00000525067.1
ENST00000367822.5
ENST00000367837.5
HBS1L
HBS1-like (S. cerevisiae)
chr8_-_141931287 0.17 ENST00000517887.1
PTK2
protein tyrosine kinase 2
chr11_-_122933043 0.17 ENST00000534624.1
ENST00000453788.2
ENST00000527387.1
HSPA8
heat shock 70kDa protein 8
chr9_+_841690 0.17 ENST00000382276.3
DMRT1
doublesex and mab-3 related transcription factor 1
chrX_-_128782722 0.16 ENST00000427399.1
APLN
apelin
chr8_+_145065521 0.16 ENST00000534791.1
GRINA
glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding)
chr13_-_31736478 0.16 ENST00000445273.2
HSPH1
heat shock 105kDa/110kDa protein 1
chr18_-_47376197 0.16 ENST00000592688.1
MYO5B
myosin VB
chr2_+_158733088 0.16 ENST00000605860.1
UPP2
uridine phosphorylase 2
chr1_-_112531777 0.15 ENST00000315987.2
ENST00000302127.4
KCND3
potassium voltage-gated channel, Shal-related subfamily, member 3
chr1_+_27248203 0.15 ENST00000321265.5
NUDC
nudC nuclear distribution protein
chr8_+_134125727 0.15 ENST00000521107.1
TG
thyroglobulin
chr5_+_79331164 0.15 ENST00000350881.2
THBS4
thrombospondin 4
chr10_-_104913367 0.15 ENST00000423468.2
NT5C2
5'-nucleotidase, cytosolic II
chr13_+_42712178 0.15 ENST00000536612.1
DGKH
diacylglycerol kinase, eta
chr5_-_112770674 0.14 ENST00000390666.3
TSSK1B
testis-specific serine kinase 1B
chr6_+_44215603 0.14 ENST00000371554.1
HSP90AB1
heat shock protein 90kDa alpha (cytosolic), class B member 1
chr12_-_45270077 0.14 ENST00000551601.1
ENST00000549027.1
ENST00000452445.2
NELL2
NEL-like 2 (chicken)
chr15_-_43785303 0.14 ENST00000382039.3
ENST00000450115.2
ENST00000382044.4
TP53BP1
tumor protein p53 binding protein 1
chr5_+_56469775 0.14 ENST00000424459.3
GPBP1
GC-rich promoter binding protein 1
chr6_-_135375921 0.14 ENST00000367820.2
ENST00000314674.3
ENST00000524715.1
ENST00000415177.2
ENST00000367826.2
HBS1L
HBS1-like (S. cerevisiae)
chr3_-_112360116 0.14 ENST00000206423.3
ENST00000439685.2
CCDC80
coiled-coil domain containing 80
chr19_-_55691377 0.14 ENST00000589172.1
SYT5
synaptotagmin V
chr11_-_82997371 0.14 ENST00000525503.1
CCDC90B
coiled-coil domain containing 90B
chr20_+_57427765 0.14 ENST00000371100.4
GNAS
GNAS complex locus
chr20_+_58203664 0.14 ENST00000541461.1
PHACTR3
phosphatase and actin regulator 3
chr19_+_17416609 0.14 ENST00000602206.1
MRPL34
mitochondrial ribosomal protein L34
chr16_-_30125177 0.13 ENST00000406256.3
GDPD3
glycerophosphodiester phosphodiesterase domain containing 3
chr10_-_90611566 0.13 ENST00000371930.4
ANKRD22
ankyrin repeat domain 22
chr3_-_171489085 0.13 ENST00000418087.1
PLD1
phospholipase D1, phosphatidylcholine-specific
chr19_-_55691614 0.13 ENST00000592470.1
ENST00000354308.3
SYT5
synaptotagmin V
chr1_-_184006611 0.13 ENST00000546159.1
COLGALT2
collagen beta(1-O)galactosyltransferase 2
chr18_-_22804637 0.12 ENST00000577775.1
ZNF521
zinc finger protein 521
chr12_-_45269430 0.12 ENST00000395487.2
NELL2
NEL-like 2 (chicken)
chr12_-_45269769 0.12 ENST00000548826.1
NELL2
NEL-like 2 (chicken)
chr14_+_32963433 0.11 ENST00000554410.1
AKAP6
A kinase (PRKA) anchor protein 6
chr4_+_76932375 0.11 ENST00000513122.1
ART3
ADP-ribosyltransferase 3
chr5_+_56469843 0.11 ENST00000514387.2
GPBP1
GC-rich promoter binding protein 1
chr21_-_30445886 0.11 ENST00000431234.1
ENST00000540844.1
ENST00000286788.4
CCT8
chaperonin containing TCP1, subunit 8 (theta)
chr11_-_111781454 0.11 ENST00000533280.1
CRYAB
crystallin, alpha B
chrX_-_152989531 0.11 ENST00000458587.2
ENST00000416815.1
BCAP31
B-cell receptor-associated protein 31
chr4_+_76932326 0.11 ENST00000513353.1
ENST00000341029.5
ART3
ADP-ribosyltransferase 3
chr19_-_55691472 0.10 ENST00000537500.1
SYT5
synaptotagmin V
chr17_-_56494713 0.10 ENST00000407977.2
RNF43
ring finger protein 43
chrX_-_102941596 0.10 ENST00000441076.2
ENST00000422355.1
ENST00000442614.1
ENST00000422154.2
ENST00000451301.1
MORF4L2
mortality factor 4 like 2
chr9_-_34589734 0.10 ENST00000378980.3
CNTFR
ciliary neurotrophic factor receptor
chr14_+_101293687 0.09 ENST00000455286.1
MEG3
maternally expressed 3 (non-protein coding)
chr6_+_32121218 0.09 ENST00000414204.1
ENST00000361568.2
ENST00000395523.1
PPT2
palmitoyl-protein thioesterase 2
chr1_-_228613026 0.09 ENST00000366696.1
HIST3H3
histone cluster 3, H3
chrX_-_72347916 0.09 ENST00000373518.1
NAP1L6
nucleosome assembly protein 1-like 6
chr14_-_94970559 0.09 ENST00000556881.1
SERPINA12
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 12
chr7_-_80548493 0.09 ENST00000536800.1
SEMA3C
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
chr11_+_65769550 0.09 ENST00000312175.2
ENST00000445560.2
ENST00000530204.1
BANF1
barrier to autointegration factor 1
chrX_-_19983260 0.09 ENST00000340625.3
CXorf23
chromosome X open reading frame 23
chr6_+_106534192 0.09 ENST00000369091.2
ENST00000369096.4
PRDM1
PR domain containing 1, with ZNF domain
chr5_+_56469939 0.09 ENST00000506184.2
GPBP1
GC-rich promoter binding protein 1
chr2_-_85581701 0.08 ENST00000295802.4
RETSAT
retinol saturase (all-trans-retinol 13,14-reductase)
chr11_-_89956461 0.08 ENST00000320585.6
CHORDC1
cysteine and histidine-rich domain (CHORD) containing 1
chr6_+_32121789 0.08 ENST00000437001.2
ENST00000375137.2
PPT2
palmitoyl-protein thioesterase 2
chr2_-_85581623 0.08 ENST00000449375.1
ENST00000409984.2
ENST00000457495.2
ENST00000263854.6
RETSAT
retinol saturase (all-trans-retinol 13,14-reductase)
chr15_+_65134088 0.08 ENST00000323544.4
ENST00000437723.1
PLEKHO2
AC069368.3
pleckstrin homology domain containing, family O member 2
Uncharacterized protein
chr1_-_197744763 0.07 ENST00000422998.1
DENND1B
DENN/MADD domain containing 1B
chr16_+_68119764 0.07 ENST00000570212.1
ENST00000562926.1
NFATC3
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3
chr17_-_56494908 0.07 ENST00000577716.1
RNF43
ring finger protein 43
chr11_+_27062502 0.07 ENST00000263182.3
BBOX1
butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
chr14_+_89060739 0.07 ENST00000318308.6
ZC3H14
zinc finger CCCH-type containing 14
chr11_+_71791693 0.06 ENST00000289488.2
ENST00000447974.1
LRTOMT
leucine rich transmembrane and O-methyltransferase domain containing
chr4_-_186877502 0.06 ENST00000431902.1
ENST00000284776.7
ENST00000415274.1
SORBS2
sorbin and SH3 domain containing 2
chr3_+_96533621 0.06 ENST00000542517.1
ENST00000506569.1
EPHA6
EPH receptor A6
chr1_-_248005254 0.06 ENST00000355784.2
OR11L1
olfactory receptor, family 11, subfamily L, member 1
chr17_-_7297833 0.06 ENST00000571802.1
ENST00000576201.1
ENST00000573213.1
ENST00000324822.11
TMEM256-PLSCR3
TMEM256-PLSCR3 readthrough (NMD candidate)
chr11_+_71791803 0.06 ENST00000539271.1
LRTOMT
leucine rich transmembrane and O-methyltransferase domain containing
chr17_-_56494882 0.06 ENST00000584437.1
RNF43
ring finger protein 43
chr4_-_186877806 0.06 ENST00000355634.5
SORBS2
sorbin and SH3 domain containing 2
chr7_-_103086598 0.06 ENST00000339444.6
ENST00000356767.4
ENST00000393735.2
ENST00000306312.3
ENST00000432958.2
SLC26A5
solute carrier family 26 (anion exchanger), member 5
chr5_+_139505520 0.05 ENST00000333305.3
IGIP
IgA-inducing protein
chr18_-_52989525 0.05 ENST00000457482.3
TCF4
transcription factor 4
chrX_-_107225600 0.05 ENST00000302917.1
TEX13B
testis expressed 13B
chr13_-_31736027 0.05 ENST00000380406.5
ENST00000320027.5
ENST00000380405.4
HSPH1
heat shock 105kDa/110kDa protein 1
chr12_+_58138664 0.05 ENST00000257910.3
TSPAN31
tetraspanin 31
chr9_-_34589700 0.05 ENST00000351266.4
CNTFR
ciliary neurotrophic factor receptor
chr1_-_6453399 0.05 ENST00000608083.1
ACOT7
acyl-CoA thioesterase 7
chr3_+_186692745 0.05 ENST00000438590.1
ST6GAL1
ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
chr7_+_132333553 0.05 ENST00000332558.4
AC009365.3
AC009365.3
chr3_+_96533413 0.05 ENST00000470610.2
ENST00000389672.5
EPHA6
EPH receptor A6
chr5_+_148443113 0.05 ENST00000507373.1
CTC-529P8.1
CTC-529P8.1
chr11_-_111781610 0.04 ENST00000525823.1
CRYAB
crystallin, alpha B
chr7_-_4901625 0.04 ENST00000404991.1
PAPOLB
poly(A) polymerase beta (testis specific)
chrX_-_138304939 0.04 ENST00000448673.1
FGF13
fibroblast growth factor 13
chr6_+_32121908 0.04 ENST00000375143.2
ENST00000424499.1
PPT2
palmitoyl-protein thioesterase 2
chrX_+_115301975 0.04 ENST00000371906.4
AGTR2
angiotensin II receptor, type 2
chr10_-_1246300 0.04 ENST00000381310.3
ADARB2
adenosine deaminase, RNA-specific, B2 (non-functional)
chr17_-_60883993 0.04 ENST00000583803.1
ENST00000456609.2
MARCH10
membrane-associated ring finger (C3HC4) 10, E3 ubiquitin protein ligase

Network of associatons between targets according to the STRING database.

First level regulatory network of HSF2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0010160 sensory organ boundary specification(GO:0008052) formation of organ boundary(GO:0010160) taste bud development(GO:0061193)
0.1 0.9 GO:0010193 response to ozone(GO:0010193)
0.1 2.4 GO:0043587 tongue morphogenesis(GO:0043587)
0.1 0.7 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.1 0.8 GO:1901908 diadenosine polyphosphate catabolic process(GO:0015961) diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.1 0.8 GO:1902045 negative regulation of Fas signaling pathway(GO:1902045)
0.1 0.9 GO:1903786 mycotoxin catabolic process(GO:0043387) aflatoxin catabolic process(GO:0046223) organic heteropentacyclic compound catabolic process(GO:1901377) regulation of glutathione biosynthetic process(GO:1903786) positive regulation of glutathione biosynthetic process(GO:1903788)
0.1 0.8 GO:0014718 positive regulation of satellite cell activation involved in skeletal muscle regeneration(GO:0014718)
0.1 0.5 GO:0009956 radial pattern formation(GO:0009956)
0.1 2.4 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
0.1 0.7 GO:0051684 maintenance of Golgi location(GO:0051684)
0.1 0.4 GO:1904764 negative regulation of fibril organization(GO:1902904) chaperone-mediated autophagy translocation complex disassembly(GO:1904764)
0.1 0.7 GO:0098728 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
0.1 0.5 GO:1903750 regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903750) negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903751)
0.1 0.4 GO:0021764 amygdala development(GO:0021764)
0.1 0.4 GO:1900245 positive regulation of MDA-5 signaling pathway(GO:1900245)
0.1 0.3 GO:0043335 protein unfolding(GO:0043335)
0.1 0.2 GO:0036116 medium-chain fatty-acyl-CoA catabolic process(GO:0036114) long-chain fatty-acyl-CoA catabolic process(GO:0036116) palmitic acid metabolic process(GO:1900533) palmitic acid biosynthetic process(GO:1900535)
0.1 0.2 GO:0043397 corticotropin-releasing hormone secretion(GO:0043396) regulation of corticotropin-releasing hormone secretion(GO:0043397) positive regulation of corticotropin-releasing hormone secretion(GO:0051466)
0.1 0.7 GO:0046598 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401) positive regulation of viral entry into host cell(GO:0046598)
0.1 0.4 GO:1904154 positive regulation of retrograde protein transport, ER to cytosol(GO:1904154)
0.1 0.4 GO:0007296 vitellogenesis(GO:0007296)
0.1 0.3 GO:1902938 regulation of intracellular calcium activated chloride channel activity(GO:1902938) neuron projection maintenance(GO:1990535)
0.0 0.2 GO:0038018 Wnt receptor catabolic process(GO:0038018)
0.0 0.4 GO:0071492 cellular response to UV-A(GO:0071492)
0.0 0.0 GO:0035566 regulation of metanephros size(GO:0035566)
0.0 0.5 GO:0034625 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.2 GO:0097475 motor neuron migration(GO:0097475)
0.0 0.7 GO:0032287 peripheral nervous system myelin maintenance(GO:0032287)
0.0 0.9 GO:0035376 sterol import(GO:0035376) cholesterol import(GO:0070508)
0.0 0.1 GO:1903660 negative regulation of complement-dependent cytotoxicity(GO:1903660)
0.0 0.6 GO:0030213 hyaluronan biosynthetic process(GO:0030213)
0.0 0.2 GO:0032439 endosome localization(GO:0032439)
0.0 0.2 GO:0046108 uridine metabolic process(GO:0046108)
0.0 0.1 GO:1990654 sebum secreting cell proliferation(GO:1990654)
0.0 0.2 GO:0060903 positive regulation of meiosis I(GO:0060903)
0.0 0.4 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.0 0.2 GO:0097623 potassium ion export across plasma membrane(GO:0097623)
0.0 0.4 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.0 0.1 GO:0071603 endothelial cell-cell adhesion(GO:0071603)
0.0 0.4 GO:0015671 oxygen transport(GO:0015671)
0.0 0.2 GO:0035799 ureter maturation(GO:0035799)
0.0 0.4 GO:0007021 tubulin complex assembly(GO:0007021)
0.0 0.1 GO:0040032 post-embryonic body morphogenesis(GO:0040032)
0.0 0.2 GO:0098734 macromolecule depalmitoylation(GO:0098734)
0.0 0.2 GO:0015712 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.0 1.2 GO:0043268 positive regulation of potassium ion transport(GO:0043268)
0.0 0.3 GO:0060219 camera-type eye photoreceptor cell differentiation(GO:0060219)
0.0 0.0 GO:0007402 ganglion mother cell fate determination(GO:0007402)
0.0 0.0 GO:0030718 germ-line stem cell population maintenance(GO:0030718)
0.0 0.5 GO:0036120 cellular response to platelet-derived growth factor stimulus(GO:0036120)
0.0 0.1 GO:0070120 ciliary neurotrophic factor-mediated signaling pathway(GO:0070120)
0.0 0.1 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.0 0.3 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.0 0.2 GO:0090091 positive regulation of extracellular matrix disassembly(GO:0090091)
0.0 0.2 GO:0033227 dsRNA transport(GO:0033227)
0.0 0.2 GO:0038007 netrin-activated signaling pathway(GO:0038007)
0.0 0.8 GO:0048488 synaptic vesicle endocytosis(GO:0048488)
0.0 0.2 GO:0007342 fusion of sperm to egg plasma membrane(GO:0007342)
0.0 0.2 GO:0015705 iodide transport(GO:0015705)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0016222 procollagen-proline 4-dioxygenase complex(GO:0016222)
0.1 0.4 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.1 0.7 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.1 0.4 GO:1990769 proximal neuron projection(GO:1990769)
0.1 0.4 GO:0098575 lumenal side of lysosomal membrane(GO:0098575)
0.1 0.4 GO:0005784 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.0 0.2 GO:0031592 centrosomal corona(GO:0031592)
0.0 0.1 GO:0097059 CNTFR-CLCF1 complex(GO:0097059)
0.0 2.4 GO:0045095 keratin filament(GO:0045095)
0.0 0.8 GO:0071682 endocytic vesicle lumen(GO:0071682)
0.0 0.4 GO:0097512 cardiac myofibril(GO:0097512)
0.0 0.1 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.0 0.4 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 0.6 GO:0031258 lamellipodium membrane(GO:0031258)
0.0 0.2 GO:0045179 apical cortex(GO:0045179)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 GO:0052847 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432) inositol diphosphate tetrakisphosphate diphosphatase activity(GO:0052840) inositol bisdiphosphate tetrakisphosphate diphosphatase activity(GO:0052841) inositol diphosphate pentakisphosphate diphosphatase activity(GO:0052842) inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity(GO:0052843) inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity(GO:0052844) inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity(GO:0052845) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity(GO:0052846) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052847) inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052848)
0.1 0.7 GO:0070728 leucine binding(GO:0070728)
0.1 0.4 GO:0052810 1-phosphatidylinositol-5-kinase activity(GO:0052810)
0.1 0.7 GO:0019798 procollagen-proline 4-dioxygenase activity(GO:0004656) procollagen-proline dioxygenase activity(GO:0019798)
0.1 0.5 GO:0005166 neurotrophin p75 receptor binding(GO:0005166)
0.1 0.2 GO:0004346 glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.1 0.4 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.0 0.1 GO:0050146 nucleoside phosphotransferase activity(GO:0050146)
0.0 0.9 GO:0032052 bile acid binding(GO:0032052)
0.0 0.3 GO:1903135 cupric ion binding(GO:1903135)
0.0 0.5 GO:0009922 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.2 GO:0050211 procollagen galactosyltransferase activity(GO:0050211)
0.0 0.9 GO:0008391 arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392)
0.0 0.2 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.0 0.1 GO:0002134 pyrimidine nucleoside binding(GO:0001884) UTP binding(GO:0002134) sulfonylurea receptor binding(GO:0017098) pyrimidine ribonucleoside binding(GO:0032551)
0.0 0.5 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 0.8 GO:0031432 titin binding(GO:0031432)
0.0 0.6 GO:0043225 anion transmembrane-transporting ATPase activity(GO:0043225)
0.0 0.2 GO:0004850 uridine phosphorylase activity(GO:0004850)
0.0 0.2 GO:0051033 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.0 0.3 GO:0030911 TPR domain binding(GO:0030911)
0.0 0.4 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 0.3 GO:0019534 toxin transporter activity(GO:0019534)
0.0 0.4 GO:0005344 oxygen transporter activity(GO:0005344)
0.0 0.2 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.0 0.2 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.0 0.9 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.4 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.1 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.0 0.2 GO:0043515 kinetochore binding(GO:0043515)
0.0 0.2 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.0 0.8 GO:0005123 death receptor binding(GO:0005123)
0.0 0.6 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 0.4 GO:0023026 MHC class II protein complex binding(GO:0023026)
0.0 0.2 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.1 GO:0004897 ciliary neurotrophic factor receptor activity(GO:0004897)
0.0 0.2 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.0 0.1 GO:0016206 catechol O-methyltransferase activity(GO:0016206)
0.0 0.3 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.9 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 0.2 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.0 0.1 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.0 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.0 0.5 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.1 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0 0.9 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.0 0.7 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.6 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.0 0.5 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.0 0.9 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.0 0.5 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 0.4 REACTOME SEMA3A PAK DEPENDENT AXON REPULSION Genes involved in Sema3A PAK dependent Axon repulsion
0.0 0.1 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.0 0.4 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks