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SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for IKZF2

Z-value: 1.37

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Transcription factors associated with IKZF2

Gene Symbol Gene ID Gene Info
IKZF2
ENSG00000030419.12 IKAROS family zinc finger 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
IKZF2hg19_v2_chr2_-_214016314_2140163430.975.5e-13Click!

Activity profile of IKZF2 motif

Sorted Z-values of IKZF2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr12_-_28125638 6.66 ENST00000545234.1
PTHLH
parathyroid hormone-like hormone
chr1_+_158979686 4.49 ENST00000368132.3
ENST00000295809.7
IFI16
interferon, gamma-inducible protein 16
chr1_+_158979680 4.43 ENST00000368131.4
ENST00000340979.6
IFI16
interferon, gamma-inducible protein 16
chr16_+_82660560 4.40 ENST00000268613.10
ENST00000565636.1
ENST00000431540.3
ENST00000428848.3
CDH13
cadherin 13
chr12_-_52867569 4.32 ENST00000252250.6
KRT6C
keratin 6C
chr19_-_42947121 4.09 ENST00000601181.1
CXCL17
chemokine (C-X-C motif) ligand 17
chr17_-_39093672 3.82 ENST00000209718.3
ENST00000436344.3
ENST00000485751.1
KRT23
keratin 23 (histone deacetylase inducible)
chr2_-_214014959 3.81 ENST00000442445.1
ENST00000457361.1
ENST00000342002.2
IKZF2
IKAROS family zinc finger 2 (Helios)
chr12_-_50677255 3.74 ENST00000551691.1
ENST00000394943.3
ENST00000341247.4
LIMA1
LIM domain and actin binding 1
chr11_+_58938903 3.65 ENST00000532982.1
DTX4
deltex homolog 4 (Drosophila)
chr1_+_158979792 3.60 ENST00000359709.3
ENST00000430894.2
IFI16
interferon, gamma-inducible protein 16
chr6_+_144665237 3.58 ENST00000421035.2
UTRN
utrophin
chr13_-_38172863 3.58 ENST00000541481.1
ENST00000379743.4
ENST00000379742.4
ENST00000379749.4
ENST00000541179.1
ENST00000379747.4
POSTN
periostin, osteoblast specific factor
chr21_-_28215332 3.32 ENST00000517777.1
ADAMTS1
ADAM metallopeptidase with thrombospondin type 1 motif, 1
chr6_+_106988986 3.20 ENST00000457437.1
ENST00000535438.1
AIM1
absent in melanoma 1
chr2_-_237416071 3.01 ENST00000309507.5
ENST00000431676.2
IQCA1
IQ motif containing with AAA domain 1
chr2_+_158114051 2.97 ENST00000259056.4
GALNT5
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 5 (GalNAc-T5)
chr7_-_127672146 2.92 ENST00000476782.1
LRRC4
leucine rich repeat containing 4
chr10_-_98031265 2.80 ENST00000224337.5
ENST00000371176.2
BLNK
B-cell linker
chr5_-_42811986 2.79 ENST00000511224.1
ENST00000507920.1
ENST00000510965.1
SEPP1
selenoprotein P, plasma, 1
chr14_-_36988882 2.74 ENST00000498187.2
NKX2-1
NK2 homeobox 1
chr4_+_26322409 2.74 ENST00000514807.1
ENST00000348160.4
ENST00000509158.1
ENST00000355476.3
RBPJ
recombination signal binding protein for immunoglobulin kappa J region
chr15_+_43885252 2.66 ENST00000453782.1
ENST00000300283.6
ENST00000437924.1
ENST00000450086.2
CKMT1B
creatine kinase, mitochondrial 1B
chr1_+_68150744 2.54 ENST00000370986.4
ENST00000370985.3
GADD45A
growth arrest and DNA-damage-inducible, alpha
chr15_+_43985084 2.51 ENST00000434505.1
ENST00000411750.1
CKMT1A
creatine kinase, mitochondrial 1A
chr15_+_43985725 2.46 ENST00000413453.2
CKMT1A
creatine kinase, mitochondrial 1A
chr2_-_237416181 2.42 ENST00000409907.3
IQCA1
IQ motif containing with AAA domain 1
chr6_-_31846744 2.42 ENST00000414427.1
ENST00000229729.6
ENST00000375562.4
SLC44A4
solute carrier family 44, member 4
chr9_+_132099158 2.41 ENST00000444125.1
RP11-65J3.1
RP11-65J3.1
chr13_+_73629107 2.40 ENST00000539231.1
KLF5
Kruppel-like factor 5 (intestinal)
chr1_+_79115503 2.39 ENST00000370747.4
ENST00000438486.1
ENST00000545124.1
IFI44
interferon-induced protein 44
chr4_-_83765613 2.38 ENST00000503937.1
SEC31A
SEC31 homolog A (S. cerevisiae)
chr3_+_118905564 2.37 ENST00000460625.1
UPK1B
uroplakin 1B
chr10_-_98031310 2.36 ENST00000427367.2
ENST00000413476.2
BLNK
B-cell linker
chr2_-_216240386 2.33 ENST00000438981.1
FN1
fibronectin 1
chr3_-_18480260 2.33 ENST00000454909.2
SATB1
SATB homeobox 1
chr5_-_42812143 2.33 ENST00000514985.1
SEPP1
selenoprotein P, plasma, 1
chrX_+_100805496 2.32 ENST00000372829.3
ARMCX1
armadillo repeat containing, X-linked 1
chr20_-_45981138 2.24 ENST00000446994.2
ZMYND8
zinc finger, MYND-type containing 8
chr6_-_75912508 2.23 ENST00000416123.2
COL12A1
collagen, type XII, alpha 1
chr4_-_74486217 2.20 ENST00000335049.5
ENST00000307439.5
RASSF6
Ras association (RalGDS/AF-6) domain family member 6
chr3_+_171844762 2.17 ENST00000443501.1
FNDC3B
fibronectin type III domain containing 3B
chr11_-_8892464 2.17 ENST00000527347.1
ENST00000526241.1
ENST00000526126.1
ENST00000530938.1
ENST00000526057.1
ST5
suppression of tumorigenicity 5
chr9_+_34989638 2.16 ENST00000453597.3
ENST00000335998.3
ENST00000312316.5
DNAJB5
DnaJ (Hsp40) homolog, subfamily B, member 5
chrX_-_43741594 2.15 ENST00000536181.1
ENST00000378069.4
MAOB
monoamine oxidase B
chr1_+_117963209 2.14 ENST00000449370.2
MAN1A2
mannosidase, alpha, class 1A, member 2
chr1_+_24646002 2.12 ENST00000356046.2
GRHL3
grainyhead-like 3 (Drosophila)
chr12_-_26278030 2.09 ENST00000242728.4
BHLHE41
basic helix-loop-helix family, member e41
chr3_-_18466026 2.08 ENST00000417717.2
SATB1
SATB homeobox 1
chr1_+_24645865 2.06 ENST00000342072.4
GRHL3
grainyhead-like 3 (Drosophila)
chr2_-_230787879 2.03 ENST00000435716.1
TRIP12
thyroid hormone receptor interactor 12
chr15_+_96876340 2.00 ENST00000453270.2
NR2F2
nuclear receptor subfamily 2, group F, member 2
chr1_+_24645807 1.97 ENST00000361548.4
GRHL3
grainyhead-like 3 (Drosophila)
chr3_+_156393349 1.97 ENST00000473702.1
TIPARP
TCDD-inducible poly(ADP-ribose) polymerase
chr7_-_135194822 1.92 ENST00000428680.2
ENST00000315544.5
ENST00000423368.2
ENST00000451834.1
ENST00000361528.4
ENST00000356162.4
ENST00000541284.1
CNOT4
CCR4-NOT transcription complex, subunit 4
chr1_+_100111580 1.89 ENST00000605497.1
PALMD
palmdelphin
chr4_-_74486347 1.84 ENST00000342081.3
RASSF6
Ras association (RalGDS/AF-6) domain family member 6
chr21_+_39628852 1.83 ENST00000398938.2
KCNJ15
potassium inwardly-rectifying channel, subfamily J, member 15
chr17_+_7387677 1.83 ENST00000322644.6
POLR2A
polymerase (RNA) II (DNA directed) polypeptide A, 220kDa
chr18_+_12288288 1.82 ENST00000586226.1
RP11-64C12.8
RP11-64C12.8
chr15_+_43885799 1.77 ENST00000449946.1
ENST00000417289.1
CKMT1B
creatine kinase, mitochondrial 1B
chr1_-_161337662 1.77 ENST00000367974.1
C1orf192
chromosome 1 open reading frame 192
chr6_+_116691001 1.75 ENST00000537543.1
DSE
dermatan sulfate epimerase
chr1_+_24645915 1.75 ENST00000350501.5
GRHL3
grainyhead-like 3 (Drosophila)
chr6_-_128841503 1.74 ENST00000368215.3
ENST00000532331.1
ENST00000368213.5
ENST00000368207.3
ENST00000525459.1
ENST00000368210.3
ENST00000368226.4
ENST00000368227.3
PTPRK
protein tyrosine phosphatase, receptor type, K
chr12_+_15154767 1.73 ENST00000542689.1
RP11-508P1.2
RP11-508P1.2
chr15_+_73976545 1.73 ENST00000318443.5
ENST00000537340.2
ENST00000318424.5
CD276
CD276 molecule
chr4_-_146859623 1.73 ENST00000379448.4
ENST00000513320.1
ZNF827
zinc finger protein 827
chr2_-_216257849 1.70 ENST00000456923.1
FN1
fibronectin 1
chr6_-_11779403 1.70 ENST00000414691.3
ADTRP
androgen-dependent TFPI-regulating protein
chr16_+_82660635 1.68 ENST00000567445.1
ENST00000446376.2
CDH13
cadherin 13
chr11_-_65429891 1.64 ENST00000527874.1
RELA
v-rel avian reticuloendotheliosis viral oncogene homolog A
chrX_-_30993201 1.62 ENST00000288422.2
ENST00000378932.2
TAB3
TGF-beta activated kinase 1/MAP3K7 binding protein 3
chr2_+_102953608 1.61 ENST00000311734.2
ENST00000409584.1
IL1RL1
interleukin 1 receptor-like 1
chr7_-_127671674 1.60 ENST00000478726.1
LRRC4
leucine rich repeat containing 4
chr4_-_74486109 1.58 ENST00000395777.2
RASSF6
Ras association (RalGDS/AF-6) domain family member 6
chr9_+_2159850 1.58 ENST00000416751.1
SMARCA2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr6_+_149539767 1.56 ENST00000606202.1
ENST00000536230.1
ENST00000445901.1
TAB2
RP1-111D6.3
TGF-beta activated kinase 1/MAP3K7 binding protein 2
RP1-111D6.3
chr3_-_71294304 1.56 ENST00000498215.1
FOXP1
forkhead box P1
chr4_-_157892167 1.54 ENST00000541126.1
PDGFC
platelet derived growth factor C
chr20_+_58179582 1.52 ENST00000371015.1
ENST00000395639.4
PHACTR3
phosphatase and actin regulator 3
chr3_+_193853927 1.52 ENST00000232424.3
HES1
hes family bHLH transcription factor 1
chr1_-_68698197 1.49 ENST00000370973.2
ENST00000370971.1
WLS
wntless Wnt ligand secretion mediator
chrX_-_15619076 1.48 ENST00000252519.3
ACE2
angiotensin I converting enzyme 2
chr1_+_112938803 1.47 ENST00000271277.6
CTTNBP2NL
CTTNBP2 N-terminal like
chr6_-_10412600 1.47 ENST00000379608.3
TFAP2A
transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
chr11_-_65430251 1.42 ENST00000534283.1
ENST00000527749.1
ENST00000533187.1
ENST00000525693.1
ENST00000534558.1
ENST00000532879.1
ENST00000532999.1
RELA
v-rel avian reticuloendotheliosis viral oncogene homolog A
chr4_-_146859787 1.42 ENST00000508784.1
ZNF827
zinc finger protein 827
chr4_-_153303658 1.41 ENST00000296555.5
FBXW7
F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
chr8_-_72268721 1.37 ENST00000419131.1
ENST00000388743.2
EYA1
eyes absent homolog 1 (Drosophila)
chr20_-_50808236 1.36 ENST00000361387.2
ZFP64
ZFP64 zinc finger protein
chr9_+_22646189 1.35 ENST00000436786.1
RP11-399D6.2
RP11-399D6.2
chr11_+_71903169 1.34 ENST00000393676.3
FOLR1
folate receptor 1 (adult)
chr1_-_28384598 1.33 ENST00000373864.1
EYA3
eyes absent homolog 3 (Drosophila)
chr5_-_133706695 1.32 ENST00000521755.1
ENST00000523054.1
ENST00000435240.2
ENST00000609654.1
ENST00000536186.1
ENST00000609383.1
CDKL3
cyclin-dependent kinase-like 3
chr1_+_150954493 1.31 ENST00000368947.4
ANXA9
annexin A9
chr13_-_46756351 1.31 ENST00000323076.2
LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr4_+_26322185 1.30 ENST00000361572.6
RBPJ
recombination signal binding protein for immunoglobulin kappa J region
chr3_+_57882061 1.29 ENST00000461354.1
ENST00000466255.1
SLMAP
sarcolemma associated protein
chr3_+_177159695 1.29 ENST00000442937.1
LINC00578
long intergenic non-protein coding RNA 578
chr1_-_68698222 1.28 ENST00000370976.3
ENST00000354777.2
ENST00000262348.4
ENST00000540432.1
WLS
wntless Wnt ligand secretion mediator
chr12_-_104443890 1.28 ENST00000547583.1
ENST00000360814.4
ENST00000546851.1
GLT8D2
glycosyltransferase 8 domain containing 2
chr4_-_157892498 1.26 ENST00000502773.1
PDGFC
platelet derived growth factor C
chr12_-_80328905 1.24 ENST00000547330.1
PPP1R12A
protein phosphatase 1, regulatory subunit 12A
chr1_+_111682058 1.23 ENST00000545121.1
CEPT1
choline/ethanolamine phosphotransferase 1
chr11_-_96076334 1.22 ENST00000524717.1
MAML2
mastermind-like 2 (Drosophila)
chr6_+_36839616 1.21 ENST00000359359.2
ENST00000510325.2
C6orf89
chromosome 6 open reading frame 89
chr6_-_112081113 1.20 ENST00000517419.1
FYN
FYN oncogene related to SRC, FGR, YES
chr17_-_7387524 1.19 ENST00000311403.4
ZBTB4
zinc finger and BTB domain containing 4
chr3_+_136649311 1.19 ENST00000469404.1
ENST00000467911.1
NCK1
NCK adaptor protein 1
chr6_-_11779014 1.19 ENST00000229583.5
ADTRP
androgen-dependent TFPI-regulating protein
chr8_+_97597148 1.18 ENST00000521590.1
SDC2
syndecan 2
chr13_-_48669204 1.18 ENST00000417167.1
MED4
mediator complex subunit 4
chr16_+_21623958 1.17 ENST00000568826.1
METTL9
methyltransferase like 9
chr8_-_128231299 1.17 ENST00000500112.1
CCAT1
colon cancer associated transcript 1 (non-protein coding)
chr4_+_124320665 1.15 ENST00000394339.2
SPRY1
sprouty homolog 1, antagonist of FGF signaling (Drosophila)
chr1_-_110155671 1.14 ENST00000351050.3
GNAT2
guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2
chr18_-_21852143 1.14 ENST00000399443.3
OSBPL1A
oxysterol binding protein-like 1A
chr13_-_48669232 1.09 ENST00000258648.2
ENST00000378586.1
MED4
mediator complex subunit 4
chr1_+_61330931 1.08 ENST00000371191.1
NFIA
nuclear factor I/A
chr3_-_71632894 1.07 ENST00000493089.1
FOXP1
forkhead box P1
chr14_+_85994943 1.06 ENST00000553678.1
RP11-497E19.2
Uncharacterized protein
chr1_-_152297679 1.06 ENST00000368799.1
FLG
filaggrin
chr8_-_133637624 1.04 ENST00000522789.1
LRRC6
leucine rich repeat containing 6
chr6_+_21593972 1.03 ENST00000244745.1
ENST00000543472.1
SOX4
SRY (sex determining region Y)-box 4
chr4_-_157892055 1.02 ENST00000422544.2
PDGFC
platelet derived growth factor C
chr17_+_4846101 1.02 ENST00000576965.1
RNF167
ring finger protein 167
chr20_+_52105495 1.01 ENST00000439873.2
AL354993.1
Cell growth-inhibiting protein 7; HCG1784586; Uncharacterized protein
chr6_+_158733692 1.00 ENST00000367094.2
ENST00000367097.3
TULP4
tubby like protein 4
chr18_+_43914159 1.00 ENST00000588679.1
ENST00000269439.7
ENST00000543885.1
RNF165
ring finger protein 165
chr12_+_122459757 0.99 ENST00000261822.4
BCL7A
B-cell CLL/lymphoma 7A
chr6_+_43149903 0.98 ENST00000252050.4
ENST00000354495.3
ENST00000372647.2
CUL9
cullin 9
chr4_-_153456153 0.97 ENST00000603548.1
FBXW7
F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
chr9_+_706842 0.97 ENST00000382293.3
KANK1
KN motif and ankyrin repeat domains 1
chr3_+_57881966 0.96 ENST00000495364.1
SLMAP
sarcolemma associated protein
chr9_-_70490107 0.95 ENST00000377395.4
ENST00000429800.2
ENST00000430059.2
ENST00000377384.1
ENST00000382405.3
CBWD5
COBW domain containing 5
chr9_+_124062071 0.95 ENST00000373818.4
GSN
gelsolin
chr5_+_43602750 0.95 ENST00000505678.2
ENST00000512422.1
ENST00000264663.5
NNT
nicotinamide nucleotide transhydrogenase
chr1_+_209941942 0.94 ENST00000487271.1
ENST00000477431.1
TRAF3IP3
TRAF3 interacting protein 3
chr7_+_123469037 0.94 ENST00000489978.1
HYAL4
hyaluronoglucosaminidase 4
chr1_+_2066387 0.93 ENST00000497183.1
PRKCZ
protein kinase C, zeta
chr5_+_122847908 0.93 ENST00000511130.2
ENST00000512718.3
CSNK1G3
casein kinase 1, gamma 3
chrX_-_24665208 0.93 ENST00000356768.4
PCYT1B
phosphate cytidylyltransferase 1, choline, beta
chr10_-_24911746 0.92 ENST00000320481.6
ARHGAP21
Rho GTPase activating protein 21
chr1_+_40627038 0.90 ENST00000372771.4
RLF
rearranged L-myc fusion
chrX_+_133507389 0.90 ENST00000370800.4
PHF6
PHD finger protein 6
chr17_+_55055466 0.89 ENST00000262288.3
ENST00000572710.1
ENST00000575395.1
SCPEP1
serine carboxypeptidase 1
chr1_+_230193521 0.89 ENST00000543760.1
GALNT2
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 2 (GalNAc-T2)
chr6_+_15246501 0.89 ENST00000341776.2
JARID2
jumonji, AT rich interactive domain 2
chrX_-_117119243 0.88 ENST00000539496.1
ENST00000469946.1
KLHL13
kelch-like family member 13
chr19_+_11200038 0.87 ENST00000558518.1
ENST00000557933.1
ENST00000455727.2
ENST00000535915.1
ENST00000545707.1
ENST00000558013.1
LDLR
low density lipoprotein receptor
chr17_+_7387919 0.87 ENST00000572844.1
POLR2A
polymerase (RNA) II (DNA directed) polypeptide A, 220kDa
chr21_+_39628780 0.86 ENST00000417042.1
KCNJ15
potassium inwardly-rectifying channel, subfamily J, member 15
chr4_+_74347400 0.86 ENST00000226355.3
AFM
afamin
chr10_+_121578211 0.85 ENST00000369080.3
INPP5F
inositol polyphosphate-5-phosphatase F
chr2_-_33824336 0.85 ENST00000431950.1
ENST00000403368.1
ENST00000441530.2
FAM98A
family with sequence similarity 98, member A
chr14_+_35591509 0.85 ENST00000604073.1
KIAA0391
KIAA0391
chrX_-_15683147 0.85 ENST00000380342.3
TMEM27
transmembrane protein 27
chr1_+_9711781 0.84 ENST00000536656.1
ENST00000377346.4
PIK3CD
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
chr5_+_173316341 0.84 ENST00000520867.1
ENST00000334035.5
CPEB4
cytoplasmic polyadenylation element binding protein 4
chr6_-_143266297 0.84 ENST00000367603.2
HIVEP2
human immunodeficiency virus type I enhancer binding protein 2
chr7_-_64451414 0.84 ENST00000282869.6
ZNF117
zinc finger protein 117
chr15_-_83837983 0.83 ENST00000562702.1
HDGFRP3
Hepatoma-derived growth factor-related protein 3
chr4_-_186733363 0.82 ENST00000393523.2
ENST00000393528.3
ENST00000449407.2
SORBS2
sorbin and SH3 domain containing 2
chr11_-_33891362 0.82 ENST00000395833.3
LMO2
LIM domain only 2 (rhombotin-like 1)
chr4_-_153274078 0.81 ENST00000263981.5
FBXW7
F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
chr8_-_101964231 0.81 ENST00000521309.1
YWHAZ
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
chr1_+_174933899 0.80 ENST00000367688.3
RABGAP1L
RAB GTPase activating protein 1-like
chr1_-_147955419 0.79 ENST00000539781.1
PPIAL4A
peptidylprolyl isomerase A (cyclophilin A)-like 4A
chr13_+_20532848 0.78 ENST00000382874.2
ZMYM2
zinc finger, MYM-type 2
chr2_-_85637459 0.77 ENST00000409921.1
CAPG
capping protein (actin filament), gelsolin-like
chr5_-_124084493 0.77 ENST00000509799.1
ZNF608
zinc finger protein 608
chr8_+_9046503 0.76 ENST00000512942.2
RP11-10A14.5
RP11-10A14.5
chr4_-_48014931 0.74 ENST00000420489.2
ENST00000504722.1
CNGA1
cyclic nucleotide gated channel alpha 1
chr15_+_40731920 0.74 ENST00000561234.1
BAHD1
bromo adjacent homology domain containing 1
chr2_-_214015111 0.74 ENST00000433134.1
IKZF2
IKAROS family zinc finger 2 (Helios)
chr13_+_76413852 0.72 ENST00000533809.2
LMO7
LIM domain 7
chr2_+_187350883 0.72 ENST00000337859.6
ZC3H15
zinc finger CCCH-type containing 15
chr3_+_57882024 0.72 ENST00000494088.1
SLMAP
sarcolemma associated protein
chr12_-_4488872 0.71 ENST00000237837.1
FGF23
fibroblast growth factor 23
chr8_+_104831554 0.71 ENST00000408894.2
RIMS2
regulating synaptic membrane exocytosis 2
chr19_+_10197463 0.71 ENST00000590378.1
ENST00000397881.3
C19orf66
chromosome 19 open reading frame 66
chr12_-_80328949 0.71 ENST00000450142.2
PPP1R12A
protein phosphatase 1, regulatory subunit 12A
chr2_-_127963343 0.71 ENST00000335247.7
CYP27C1
cytochrome P450, family 27, subfamily C, polypeptide 1
chr10_-_119805558 0.70 ENST00000369199.3
RAB11FIP2
RAB11 family interacting protein 2 (class I)
chr1_+_104198377 0.70 ENST00000370083.4
AMY1A
amylase, alpha 1A (salivary)
chr20_+_44509857 0.70 ENST00000372523.1
ENST00000372520.1
ZSWIM1
zinc finger, SWIM-type containing 1
chr13_+_20532900 0.69 ENST00000382871.2
ZMYM2
zinc finger, MYM-type 2
chr3_+_177159744 0.69 ENST00000439009.1
LINC00578
long intergenic non-protein coding RNA 578
chr14_+_91709279 0.69 ENST00000554096.1
CTD-2547L24.3
HCG1816139; Uncharacterized protein
chr1_-_11118896 0.69 ENST00000465788.1
SRM
spermidine synthase
chr10_+_13628933 0.68 ENST00000417658.1
ENST00000320054.4
PRPF18
pre-mRNA processing factor 18
chr1_+_28995258 0.67 ENST00000361872.4
ENST00000294409.2
GMEB1
glucocorticoid modulatory element binding protein 1
chr7_+_107224364 0.67 ENST00000491150.1
BCAP29
B-cell receptor-associated protein 29
chr10_+_112679301 0.66 ENST00000265277.5
ENST00000369452.4
SHOC2
soc-2 suppressor of clear homolog (C. elegans)
chr10_-_61495760 0.65 ENST00000395347.1
SLC16A9
solute carrier family 16, member 9
chr17_+_28443799 0.65 ENST00000584423.1
ENST00000247026.5
NSRP1
nuclear speckle splicing regulatory protein 1
chrX_+_100663243 0.65 ENST00000316594.5
HNRNPH2
heterogeneous nuclear ribonucleoprotein H2 (H')
chr6_+_106534192 0.64 ENST00000369091.2
ENST00000369096.4
PRDM1
PR domain containing 1, with ZNF domain
chr5_+_34685805 0.64 ENST00000508315.1
RAI14
retinoic acid induced 14

Network of associatons between targets according to the STRING database.

First level regulatory network of IKZF2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 4.0 GO:1904237 regulation of substrate-dependent cell migration, cell attachment to substrate(GO:1904235) positive regulation of substrate-dependent cell migration, cell attachment to substrate(GO:1904237)
1.0 3.1 GO:0006117 acetaldehyde metabolic process(GO:0006117)
0.9 2.7 GO:0001172 transcription, RNA-templated(GO:0001172)
0.7 2.8 GO:0061357 positive regulation of Wnt protein secretion(GO:0061357)
0.7 2.0 GO:0035508 positive regulation of myosin-light-chain-phosphatase activity(GO:0035508)
0.6 2.5 GO:0035905 ascending aorta development(GO:0035905) ascending aorta morphogenesis(GO:0035910)
0.6 3.2 GO:2000639 regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
0.6 3.6 GO:0032571 response to vitamin K(GO:0032571) regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904207) positive regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904209) bone regeneration(GO:1990523)
0.5 4.0 GO:1901189 positive regulation of ephrin receptor signaling pathway(GO:1901189) positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068)
0.5 2.0 GO:0009956 radial pattern formation(GO:0009956)
0.5 2.4 GO:0032474 otolith morphogenesis(GO:0032474)
0.4 1.3 GO:0003147 neural crest cell migration involved in heart formation(GO:0003147) anterior neural tube closure(GO:0061713)
0.4 2.6 GO:0072619 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.4 6.1 GO:0055096 lipoprotein particle mediated signaling(GO:0055095) low-density lipoprotein particle mediated signaling(GO:0055096)
0.4 1.2 GO:1903676 regulation of cap-dependent translational initiation(GO:1903674) positive regulation of cap-dependent translational initiation(GO:1903676)
0.4 3.0 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.4 2.1 GO:0014063 negative regulation of serotonin secretion(GO:0014063)
0.3 7.9 GO:0090179 planar cell polarity pathway involved in neural tube closure(GO:0090179)
0.3 1.0 GO:2000393 negative regulation of lamellipodium morphogenesis(GO:2000393)
0.3 2.1 GO:1904381 Golgi apparatus mannose trimming(GO:1904381)
0.3 1.5 GO:0003051 angiotensin-mediated drinking behavior(GO:0003051)
0.3 1.5 GO:0021557 optic cup structural organization(GO:0003409) oculomotor nerve development(GO:0021557) oculomotor nerve morphogenesis(GO:0021622) oculomotor nerve formation(GO:0021623)
0.3 1.1 GO:0051387 negative regulation of neurotrophin TRK receptor signaling pathway(GO:0051387) epithelial to mesenchymal transition involved in cardiac fibroblast development(GO:0060940)
0.3 4.9 GO:0006600 creatine metabolic process(GO:0006600)
0.3 6.8 GO:0097119 postsynaptic density protein 95 clustering(GO:0097119)
0.3 0.3 GO:2000257 regulation of protein activation cascade(GO:2000257)
0.2 2.4 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.2 1.6 GO:0038172 interleukin-33-mediated signaling pathway(GO:0038172)
0.2 0.7 GO:0071030 nuclear mRNA surveillance of spliceosomal pre-mRNA splicing(GO:0071030) nuclear retention of unspliced pre-mRNA at the site of transcription(GO:0071048)
0.2 2.7 GO:0021759 globus pallidus development(GO:0021759)
0.2 0.9 GO:1903979 negative regulation of microglial cell activation(GO:1903979)
0.2 1.4 GO:0006740 NADPH regeneration(GO:0006740)
0.2 2.0 GO:0033183 negative regulation of histone ubiquitination(GO:0033183) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315)
0.2 6.7 GO:0002076 osteoblast development(GO:0002076)
0.2 13.1 GO:0032731 positive regulation of interleukin-1 beta production(GO:0032731)
0.2 0.9 GO:1903906 plasma membrane raft distribution(GO:0044855) plasma membrane raft localization(GO:0044856) plasma membrane raft polarization(GO:0044858) regulation of plasma membrane raft polarization(GO:1903906)
0.2 3.6 GO:0014894 response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.2 3.9 GO:0090026 positive regulation of monocyte chemotaxis(GO:0090026)
0.2 3.6 GO:0001542 ovulation from ovarian follicle(GO:0001542)
0.2 2.2 GO:0006657 CDP-choline pathway(GO:0006657)
0.2 0.7 GO:0042369 regulation of vitamin D 24-hydroxylase activity(GO:0010979) positive regulation of vitamin D 24-hydroxylase activity(GO:0010980) vitamin D catabolic process(GO:0042369)
0.2 0.5 GO:1903033 regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033)
0.2 1.1 GO:0019418 sulfide oxidation(GO:0019418) sulfide oxidation, using sulfide:quinone oxidoreductase(GO:0070221)
0.2 1.2 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.2 1.2 GO:0008218 bioluminescence(GO:0008218)
0.2 0.8 GO:0060374 mast cell differentiation(GO:0060374)
0.2 0.6 GO:2000434 regulation of protein neddylation(GO:2000434) negative regulation of protein neddylation(GO:2000435)
0.2 2.0 GO:0090646 mitochondrial tRNA processing(GO:0090646)
0.2 1.6 GO:2001181 positive regulation of interleukin-10 secretion(GO:2001181)
0.2 3.3 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.1 0.9 GO:0002378 immunoglobulin biosynthetic process(GO:0002378)
0.1 1.7 GO:0045078 positive regulation of interferon-gamma biosynthetic process(GO:0045078)
0.1 0.4 GO:0021912 regulation of transcription from RNA polymerase II promoter involved in spinal cord motor neuron fate specification(GO:0021912)
0.1 3.8 GO:0007171 activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.1 1.2 GO:1901727 positive regulation of histone deacetylase activity(GO:1901727)
0.1 0.4 GO:1990654 sebum secreting cell proliferation(GO:1990654)
0.1 0.9 GO:0051684 maintenance of Golgi location(GO:0051684)
0.1 2.4 GO:0016576 histone dephosphorylation(GO:0016576)
0.1 0.5 GO:0050902 leukocyte adhesive activation(GO:0050902)
0.1 0.5 GO:0071034 CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043)
0.1 0.9 GO:0030207 chondroitin sulfate catabolic process(GO:0030207)
0.1 2.1 GO:0010944 negative regulation of transcription by competitive promoter binding(GO:0010944)
0.1 2.9 GO:1900745 positive regulation of p38MAPK cascade(GO:1900745)
0.1 1.7 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839)
0.1 2.4 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.1 1.0 GO:0021564 regulation of systemic arterial blood pressure by baroreceptor feedback(GO:0003025) vagus nerve development(GO:0021564)
0.1 0.6 GO:0021691 cerebellar Purkinje cell layer maturation(GO:0021691)
0.1 0.7 GO:0008295 spermidine biosynthetic process(GO:0008295)
0.1 1.1 GO:0042670 retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
0.1 0.8 GO:2001206 positive regulation of osteoclast development(GO:2001206)
0.1 2.1 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.1 1.2 GO:0050966 detection of mechanical stimulus involved in sensory perception of pain(GO:0050966) negative regulation of dendritic spine maintenance(GO:1902951)
0.1 0.4 GO:0061015 snRNA import into nucleus(GO:0061015)
0.1 0.5 GO:0043654 recognition of apoptotic cell(GO:0043654)
0.1 1.0 GO:0060287 epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.1 0.6 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.1 0.5 GO:0032380 regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
0.1 0.5 GO:1904220 regulation of serine C-palmitoyltransferase activity(GO:1904220)
0.1 1.0 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.1 1.7 GO:0072189 ureter development(GO:0072189)
0.1 0.6 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.1 1.1 GO:0090168 Golgi reassembly(GO:0090168)
0.1 0.4 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
0.1 0.7 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.1 0.2 GO:0051834 evasion or tolerance of host defenses by virus(GO:0019049) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) induction by symbiont of host defense response(GO:0044416) induction of host immune response by virus(GO:0046730) active induction of host immune response by virus(GO:0046732) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834) modulation by symbiont of host defense response(GO:0052031) induction by organism of defense response of other organism involved in symbiotic interaction(GO:0052251) modulation by organism of defense response of other organism involved in symbiotic interaction(GO:0052255) positive regulation by symbiont of host defense response(GO:0052509) positive regulation by organism of defense response of other organism involved in symbiotic interaction(GO:0052510) modulation by organism of immune response of other organism involved in symbiotic interaction(GO:0052552) modulation by symbiont of host immune response(GO:0052553) modulation by virus of host immune response(GO:0075528)
0.1 0.5 GO:0003344 pericardium morphogenesis(GO:0003344)
0.1 0.9 GO:0015074 DNA integration(GO:0015074)
0.1 0.4 GO:0051533 positive regulation of NFAT protein import into nucleus(GO:0051533)
0.1 0.7 GO:0061669 spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.1 0.8 GO:0035542 regulation of SNARE complex assembly(GO:0035542)
0.1 3.7 GO:0030835 negative regulation of actin filament depolymerization(GO:0030835)
0.1 0.2 GO:1903445 intermembrane transport(GO:0046909) protein transport from ciliary membrane to plasma membrane(GO:1903445)
0.1 0.2 GO:1905064 response to mycophenolic acid(GO:0071505) cellular response to mycophenolic acid(GO:0071506) metanephric glomerular mesangial cell development(GO:0072255) reversible differentiation(GO:0090677) cell dedifferentiation involved in phenotypic switching(GO:0090678) positive regulation of phenotypic switching(GO:1900241) negative regulation of vascular smooth muscle cell differentiation(GO:1905064) regulation of vascular smooth muscle cell dedifferentiation(GO:1905174) positive regulation of vascular smooth muscle cell dedifferentiation(GO:1905176) vascular smooth muscle cell dedifferentiation(GO:1990936)
0.1 0.9 GO:0042532 negative regulation of tyrosine phosphorylation of STAT protein(GO:0042532)
0.0 8.6 GO:0070268 cornification(GO:0070268)
0.0 0.2 GO:0061209 cell proliferation involved in mesonephros development(GO:0061209) mesenchymal cell proliferation involved in ureteric bud development(GO:0072138)
0.0 0.2 GO:0002678 positive regulation of chronic inflammatory response(GO:0002678) swimming behavior(GO:0036269)
0.0 0.6 GO:2000623 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.0 0.4 GO:0006848 pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475)
0.0 2.3 GO:0060325 face morphogenesis(GO:0060325)
0.0 0.6 GO:0035520 monoubiquitinated protein deubiquitination(GO:0035520)
0.0 0.9 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.0 3.2 GO:0070423 nucleotide-binding oligomerization domain containing signaling pathway(GO:0070423)
0.0 1.6 GO:0042573 retinoic acid metabolic process(GO:0042573)
0.0 0.1 GO:0072361 regulation of glycolytic process by regulation of transcription from RNA polymerase II promoter(GO:0072361)
0.0 0.3 GO:0001555 oocyte growth(GO:0001555)
0.0 2.8 GO:0010107 potassium ion import(GO:0010107)
0.0 0.7 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.0 0.5 GO:0007258 JUN phosphorylation(GO:0007258)
0.0 0.4 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.0 0.8 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
0.0 0.5 GO:0032782 bile acid secretion(GO:0032782)
0.0 0.3 GO:0040032 post-embryonic body morphogenesis(GO:0040032)
0.0 0.7 GO:0031507 heterochromatin assembly(GO:0031507)
0.0 0.7 GO:0007586 digestion(GO:0007586)
0.0 0.1 GO:0006566 threonine metabolic process(GO:0006566)
0.0 0.7 GO:0021889 olfactory bulb interneuron differentiation(GO:0021889)
0.0 0.1 GO:0044029 DNA hypomethylation(GO:0044028) hypomethylation of CpG island(GO:0044029)
0.0 0.2 GO:0003199 endocardial cushion to mesenchymal transition involved in heart valve formation(GO:0003199)
0.0 3.0 GO:0016266 O-glycan processing(GO:0016266)
0.0 0.6 GO:0000183 chromatin silencing at rDNA(GO:0000183)
0.0 0.4 GO:0008595 tripartite regional subdivision(GO:0007351) anterior/posterior axis specification, embryo(GO:0008595)
0.0 0.3 GO:0031344 regulation of cell projection organization(GO:0031344)
0.0 1.9 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.0 1.0 GO:0060384 innervation(GO:0060384)
0.0 1.3 GO:0030517 negative regulation of axon extension(GO:0030517)
0.0 0.2 GO:1902866 regulation of retina development in camera-type eye(GO:1902866)
0.0 0.2 GO:0071225 cellular response to muramyl dipeptide(GO:0071225) negative regulation of podosome assembly(GO:0071802)
0.0 0.8 GO:1901880 negative regulation of protein depolymerization(GO:1901880)
0.0 0.3 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.0 0.1 GO:0033159 negative regulation of protein import into nucleus, translocation(GO:0033159)
0.0 0.1 GO:0060474 positive regulation of sperm motility involved in capacitation(GO:0060474)
0.0 1.0 GO:0003298 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0 0.3 GO:0051964 negative regulation of synapse assembly(GO:0051964)
0.0 0.4 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.0 0.2 GO:0006013 mannose metabolic process(GO:0006013)
0.0 0.4 GO:0072643 interferon-gamma secretion(GO:0072643)
0.0 1.1 GO:0006699 bile acid biosynthetic process(GO:0006699)
0.0 0.1 GO:0030264 nuclear fragmentation involved in apoptotic nuclear change(GO:0030264) mineralocorticoid receptor signaling pathway(GO:0031959)
0.0 1.1 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.7 GO:0022400 regulation of rhodopsin mediated signaling pathway(GO:0022400)
0.0 0.2 GO:0043923 positive regulation by host of viral transcription(GO:0043923)
0.0 3.4 GO:0007219 Notch signaling pathway(GO:0007219)
0.0 0.1 GO:0030007 cellular potassium ion homeostasis(GO:0030007)
0.0 0.5 GO:0007617 mating behavior(GO:0007617) multi-organism reproductive behavior(GO:0044705)
0.0 1.5 GO:0032410 negative regulation of transporter activity(GO:0032410)
0.0 1.8 GO:0030521 androgen receptor signaling pathway(GO:0030521)
0.0 0.9 GO:0051180 vitamin transport(GO:0051180)
0.0 0.3 GO:1990118 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 0.2 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.0 0.6 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.0 0.1 GO:0042866 pyruvate biosynthetic process(GO:0042866)
0.0 0.1 GO:1901374 acetate ester transport(GO:1901374)
0.0 0.3 GO:0006089 lactate metabolic process(GO:0006089)
0.0 0.2 GO:0032515 negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.0 0.0 GO:1901421 positive regulation of response to alcohol(GO:1901421)
0.0 0.4 GO:0002793 positive regulation of peptide secretion(GO:0002793) positive regulation of peptide hormone secretion(GO:0090277)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 3.1 GO:0035525 NF-kappaB p50/p65 complex(GO:0035525)
0.7 2.2 GO:0005595 collagen type XII trimer(GO:0005595)
0.5 3.2 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.4 4.0 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.4 1.1 GO:0036457 keratohyalin granule(GO:0036457)
0.3 0.9 GO:1990666 PCSK9-LDLR complex(GO:1990666)
0.3 4.0 GO:0005577 fibrinogen complex(GO:0005577)
0.3 2.3 GO:0070847 core mediator complex(GO:0070847)
0.3 2.0 GO:0030678 mitochondrial ribonuclease P complex(GO:0030678)
0.2 3.6 GO:0070938 contractile ring(GO:0070938)
0.2 0.7 GO:0071020 post-spliceosomal complex(GO:0071020)
0.2 0.6 GO:0031213 RSF complex(GO:0031213)
0.1 1.8 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.1 2.7 GO:0000974 Prp19 complex(GO:0000974)
0.1 2.0 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.1 2.4 GO:0030127 COPII vesicle coat(GO:0030127)
0.1 1.6 GO:0045179 apical cortex(GO:0045179)
0.1 0.6 GO:0072558 NLRP1 inflammasome complex(GO:0072558)
0.1 1.9 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.1 0.9 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.1 0.7 GO:0005677 chromatin silencing complex(GO:0005677)
0.1 0.4 GO:0045211 postsynaptic membrane(GO:0045211)
0.1 1.9 GO:0030014 CCR4-NOT complex(GO:0030014)
0.1 4.1 GO:0005720 nuclear heterochromatin(GO:0005720)
0.1 0.9 GO:0030478 actin cap(GO:0030478)
0.1 1.8 GO:0005614 interstitial matrix(GO:0005614)
0.1 1.6 GO:0071564 npBAF complex(GO:0071564)
0.1 1.3 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.1 1.8 GO:0001891 phagocytic cup(GO:0001891)
0.1 2.6 GO:0032590 dendrite membrane(GO:0032590)
0.0 3.0 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.0 0.5 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 1.3 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.5 GO:0017059 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0 5.8 GO:0005901 caveola(GO:0005901)
0.0 0.8 GO:0008290 F-actin capping protein complex(GO:0008290)
0.0 0.4 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.0 0.9 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 3.0 GO:0045095 keratin filament(GO:0045095)
0.0 0.5 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0 1.0 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 0.2 GO:0098843 postsynaptic endocytic zone(GO:0098843)
0.0 3.7 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.4 GO:0061689 tricellular tight junction(GO:0061689)
0.0 0.2 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.0 0.5 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.0 0.3 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.0 0.1 GO:0002081 outer acrosomal membrane(GO:0002081)
0.0 3.2 GO:0031594 neuromuscular junction(GO:0031594)
0.0 2.2 GO:0043198 dendritic shaft(GO:0043198)
0.0 17.7 GO:0016607 nuclear speck(GO:0016607)
0.0 0.9 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.9 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.3 GO:0097504 Gemini of coiled bodies(GO:0097504)
0.0 0.8 GO:0005763 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 0.3 GO:0001673 male germ cell nucleus(GO:0001673)
0.0 0.9 GO:0097228 sperm principal piece(GO:0097228)
0.0 0.2 GO:0016013 syntrophin complex(GO:0016013)
0.0 0.3 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 0.5 GO:0044295 axonal growth cone(GO:0044295)
0.0 2.2 GO:0016363 nuclear matrix(GO:0016363)
0.0 0.5 GO:0035371 microtubule plus-end(GO:0035371)
0.0 1.5 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 2.8 GO:0043197 dendritic spine(GO:0043197)
0.0 0.1 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.0 0.9 GO:0042175 endoplasmic reticulum membrane(GO:0005789) nuclear outer membrane-endoplasmic reticulum membrane network(GO:0042175)
0.0 1.6 GO:0005604 basement membrane(GO:0005604)
0.0 1.4 GO:0005746 mitochondrial respiratory chain(GO:0005746)
0.0 2.3 GO:0072562 blood microparticle(GO:0072562)
0.0 0.5 GO:0016592 mediator complex(GO:0016592)
0.0 4.6 GO:0016324 apical plasma membrane(GO:0016324)
0.0 0.1 GO:0070876 SOSS complex(GO:0070876)
0.0 1.9 GO:0055037 recycling endosome(GO:0055037)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 6.1 GO:0055100 adiponectin binding(GO:0055100)
0.9 2.7 GO:0003968 RNA-directed RNA polymerase activity(GO:0003968)
0.6 2.8 GO:0031852 mu-type opioid receptor binding(GO:0031852)
0.5 1.6 GO:0002113 interleukin-33 binding(GO:0002113)
0.5 4.9 GO:0004111 creatine kinase activity(GO:0004111)
0.5 1.4 GO:0008746 NAD(P)+ transhydrogenase activity(GO:0008746) oxidoreductase activity, acting on NAD(P)H, NAD(P) as acceptor(GO:0016652)
0.4 3.2 GO:0050816 phosphothreonine binding(GO:0050816)
0.4 1.8 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.3 1.3 GO:0061714 folic acid receptor activity(GO:0061714)
0.3 1.2 GO:0004307 diacylglycerol cholinephosphotransferase activity(GO:0004142) ethanolaminephosphotransferase activity(GO:0004307)
0.3 2.4 GO:0045118 azole transporter activity(GO:0045118)
0.3 2.3 GO:0008241 peptidyl-dipeptidase activity(GO:0008241)
0.3 3.1 GO:0071532 ankyrin repeat binding(GO:0071532)
0.2 1.2 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
0.2 2.1 GO:0043426 MRF binding(GO:0043426)
0.2 0.7 GO:0004766 spermidine synthase activity(GO:0004766)
0.2 0.9 GO:0008431 vitamin E binding(GO:0008431)
0.2 8.2 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.2 2.2 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.2 4.0 GO:0000150 recombinase activity(GO:0000150)
0.2 0.8 GO:0010348 lithium:proton antiporter activity(GO:0010348)
0.2 0.9 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.2 1.6 GO:0008131 primary amine oxidase activity(GO:0008131)
0.2 5.1 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.2 0.5 GO:0070538 oleic acid binding(GO:0070538)
0.1 0.7 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.1 2.1 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.1 0.7 GO:0005502 11-cis retinal binding(GO:0005502) all-trans retinal binding(GO:0005503)
0.1 0.7 GO:0004556 alpha-amylase activity(GO:0004556)
0.1 0.6 GO:0071987 WD40-repeat domain binding(GO:0071987)
0.1 0.7 GO:0000386 second spliceosomal transesterification activity(GO:0000386)
0.1 0.4 GO:0070506 high-density lipoprotein particle receptor activity(GO:0070506)
0.1 1.1 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.1 0.6 GO:0008267 poly-glutamine tract binding(GO:0008267)
0.1 2.7 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.1 2.4 GO:0042809 vitamin D receptor binding(GO:0042809)
0.1 2.0 GO:0004526 ribonuclease P activity(GO:0004526)
0.1 0.9 GO:0030229 very-low-density lipoprotein particle receptor activity(GO:0030229)
0.1 1.1 GO:0015248 sterol transporter activity(GO:0015248)
0.1 3.6 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.1 2.1 GO:0045295 gamma-catenin binding(GO:0045295)
0.1 3.7 GO:0017166 vinculin binding(GO:0017166)
0.1 0.4 GO:0005477 pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.1 0.9 GO:0008934 inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate 3-phosphatase activity(GO:0052832) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834)
0.1 3.9 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.1 1.1 GO:0030280 structural constituent of epidermis(GO:0030280)
0.1 1.6 GO:0043560 insulin receptor substrate binding(GO:0043560)
0.1 0.9 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.1 1.6 GO:0044213 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.1 0.4 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
0.1 0.9 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)
0.1 0.5 GO:0016454 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.1 3.7 GO:0003785 actin monomer binding(GO:0003785)
0.1 0.9 GO:0045159 myosin II binding(GO:0045159)
0.1 0.6 GO:1990948 ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948)
0.1 2.2 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.1 1.1 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.1 0.5 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.1 0.3 GO:0016428 tRNA (cytosine-5-)-methyltransferase activity(GO:0016428)
0.1 0.5 GO:0017040 ceramidase activity(GO:0017040)
0.1 2.6 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.1 0.9 GO:0032395 MHC class II receptor activity(GO:0032395)
0.0 0.2 GO:0060422 peptidyl-dipeptidase inhibitor activity(GO:0060422)
0.0 0.7 GO:0005221 intracellular cyclic nucleotide activated cation channel activity(GO:0005221) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.0 0.2 GO:0033754 indoleamine 2,3-dioxygenase activity(GO:0033754)
0.0 2.0 GO:0001972 retinoic acid binding(GO:0001972)
0.0 0.4 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 2.6 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 7.0 GO:0031490 chromatin DNA binding(GO:0031490)
0.0 11.8 GO:0008201 heparin binding(GO:0008201)
0.0 0.2 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.0 1.3 GO:0015464 acetylcholine receptor activity(GO:0015464)
0.0 2.0 GO:0071889 14-3-3 protein binding(GO:0071889)
0.0 0.5 GO:0004705 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 11.6 GO:0001047 core promoter binding(GO:0001047)
0.0 1.0 GO:0001056 RNA polymerase III activity(GO:0001056)
0.0 2.0 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.9 GO:0046966 thyroid hormone receptor binding(GO:0046966)
0.0 0.1 GO:0005277 acetylcholine transmembrane transporter activity(GO:0005277) secondary active organic cation transmembrane transporter activity(GO:0008513) acetate ester transmembrane transporter activity(GO:1901375)
0.0 0.5 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 1.2 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 2.6 GO:0050681 androgen receptor binding(GO:0050681)
0.0 0.8 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.0 0.9 GO:0032452 histone demethylase activity(GO:0032452)
0.0 1.4 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.0 1.5 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 1.1 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.0 0.9 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.0 0.3 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.0 1.0 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.2 GO:0004559 alpha-mannosidase activity(GO:0004559)
0.0 1.8 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.0 0.3 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 2.9 GO:0042826 histone deacetylase binding(GO:0042826)
0.0 0.6 GO:0031491 nucleosome binding(GO:0031491)
0.0 0.1 GO:0004743 pyruvate kinase activity(GO:0004743)
0.0 0.3 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.0 0.1 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.0 0.2 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 0.1 GO:0030284 estrogen receptor activity(GO:0030284)
0.0 1.1 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.0 0.4 GO:0004065 arylsulfatase activity(GO:0004065)
0.0 0.4 GO:0005328 neurotransmitter:sodium symporter activity(GO:0005328)
0.0 0.1 GO:0016453 C-acetyltransferase activity(GO:0016453)
0.0 0.1 GO:0030911 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118) TPR domain binding(GO:0030911)
0.0 0.6 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 0.2 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.0 0.2 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.0 0.5 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.0 0.1 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
0.0 1.3 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.3 GO:0016891 endoribonuclease activity, producing 5'-phosphomonoesters(GO:0016891)
0.0 0.1 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.0 2.2 GO:0051087 chaperone binding(GO:0051087)
0.0 0.4 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.4 GO:0000339 RNA cap binding(GO:0000339)
0.0 0.3 GO:0008432 JUN kinase binding(GO:0008432)
0.0 0.4 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 6.1 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.1 4.8 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.1 5.8 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.1 3.1 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.1 5.3 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.1 3.8 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.1 6.9 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 4.0 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 2.3 PID MYC PATHWAY C-MYC pathway
0.0 0.5 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.0 2.1 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 3.7 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 0.9 PID AVB3 OPN PATHWAY Osteopontin-mediated events
0.0 2.9 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 1.7 PID RHOA PATHWAY RhoA signaling pathway
0.0 1.1 PID CONE PATHWAY Visual signal transduction: Cones
0.0 1.1 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.0 0.7 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.0 1.3 PID IGF1 PATHWAY IGF1 pathway
0.0 3.3 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 1.6 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 0.7 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 0.4 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 0.7 PID FGF PATHWAY FGF signaling pathway
0.0 0.9 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 0.7 PID SHP2 PATHWAY SHP2 signaling
0.0 1.1 PID AR PATHWAY Coregulation of Androgen receptor activity

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.5 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.3 5.3 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.2 3.1 REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL Genes involved in NF-kB is activated and signals survival
0.2 3.2 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.2 3.8 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.2 7.1 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.1 4.6 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.1 4.3 REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.1 2.7 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.1 6.1 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.1 1.0 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.1 1.7 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.1 2.4 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.1 5.3 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.1 2.7 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.1 1.8 REACTOME PD1 SIGNALING Genes involved in PD-1 signaling
0.1 0.7 REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS Genes involved in Regulation of Water Balance by Renal Aquaporins
0.0 4.5 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 2.5 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 2.3 REACTOME SIGNALING BY NOTCH1 Genes involved in Signaling by NOTCH1
0.0 0.7 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.0 1.4 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 1.6 REACTOME DESTABILIZATION OF MRNA BY KSRP Genes involved in Destabilization of mRNA by KSRP
0.0 0.7 REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1 Genes involved in Signaling by activated point mutants of FGFR1
0.0 0.9 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 3.9 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 1.4 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.0 1.2 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 2.5 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.0 1.5 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 3.8 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 11.2 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.0 0.9 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 0.4 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 0.5 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 1.1 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.0 0.5 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
0.0 0.6 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 0.5 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 1.7 REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.0 0.4 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.3 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 0.9 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.4 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 0.3 REACTOME PYRUVATE METABOLISM Genes involved in Pyruvate metabolism