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SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for INSM1

Z-value: 0.82

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Transcription factors associated with INSM1

Gene Symbol Gene ID Gene Info
INSM1
ENSG00000173404.3 INSM transcriptional repressor 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
INSM1hg19_v2_chr20_+_20348740_203487650.262.7e-01Click!

Activity profile of INSM1 motif

Sorted Z-values of INSM1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr12_-_52887034 5.55 ENST00000330722.6
KRT6A
keratin 6A
chr3_+_50192499 4.07 ENST00000413852.1
SEMA3F
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
chr3_+_50192537 3.91 ENST00000002829.3
SEMA3F
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
chr3_+_50192457 3.82 ENST00000414301.1
ENST00000450338.1
SEMA3F
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
chr3_+_50192833 2.51 ENST00000426511.1
SEMA3F
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
chr1_-_6321035 1.52 ENST00000377893.2
GPR153
G protein-coupled receptor 153
chr1_+_160370344 1.46 ENST00000368061.2
VANGL2
VANGL planar cell polarity protein 2
chr10_+_91061712 1.44 ENST00000371826.3
IFIT2
interferon-induced protein with tetratricopeptide repeats 2
chr12_-_54779511 1.43 ENST00000551109.1
ENST00000546970.1
ZNF385A
zinc finger protein 385A
chr20_-_45980621 1.36 ENST00000446894.1
ZMYND8
zinc finger, MYND-type containing 8
chr12_+_70760056 1.36 ENST00000258111.4
KCNMB4
potassium large conductance calcium-activated channel, subfamily M, beta member 4
chr19_+_10197463 1.32 ENST00000590378.1
ENST00000397881.3
C19orf66
chromosome 19 open reading frame 66
chr11_+_8704748 1.28 ENST00000526562.1
ENST00000525981.1
RPL27A
ribosomal protein L27a
chr1_+_2398876 1.26 ENST00000449969.1
PLCH2
phospholipase C, eta 2
chr14_+_85996507 1.14 ENST00000554746.1
FLRT2
fibronectin leucine rich transmembrane protein 2
chr4_+_26322409 1.12 ENST00000514807.1
ENST00000348160.4
ENST00000509158.1
ENST00000355476.3
RBPJ
recombination signal binding protein for immunoglobulin kappa J region
chr11_+_124933191 1.11 ENST00000532000.1
ENST00000308074.4
SLC37A2
solute carrier family 37 (glucose-6-phosphate transporter), member 2
chr19_+_10196981 1.10 ENST00000591813.1
C19orf66
chromosome 19 open reading frame 66
chr14_+_85996471 1.07 ENST00000330753.4
FLRT2
fibronectin leucine rich transmembrane protein 2
chr3_+_10857885 1.06 ENST00000254488.2
ENST00000454147.1
SLC6A11
solute carrier family 6 (neurotransmitter transporter), member 11
chr11_+_124932986 1.04 ENST00000407458.1
ENST00000298280.5
SLC37A2
solute carrier family 37 (glucose-6-phosphate transporter), member 2
chr15_+_45722727 0.96 ENST00000396650.2
ENST00000558435.1
ENST00000344300.3
C15orf48
chromosome 15 open reading frame 48
chr3_-_69062764 0.94 ENST00000295571.5
EOGT
EGF domain-specific O-linked N-acetylglucosamine (GlcNAc) transferase
chr11_+_124932955 0.94 ENST00000403796.2
SLC37A2
solute carrier family 37 (glucose-6-phosphate transporter), member 2
chr22_-_20104700 0.89 ENST00000439169.2
ENST00000445045.1
ENST00000404751.3
ENST00000252136.7
ENST00000403707.3
TRMT2A
tRNA methyltransferase 2 homolog A (S. cerevisiae)
chr4_-_143767428 0.89 ENST00000513000.1
ENST00000509777.1
ENST00000503927.1
INPP4B
inositol polyphosphate-4-phosphatase, type II, 105kDa
chr8_-_57123815 0.86 ENST00000316981.3
ENST00000423799.2
ENST00000429357.2
PLAG1
pleiomorphic adenoma gene 1
chr18_+_34409069 0.85 ENST00000543923.1
ENST00000280020.5
ENST00000435985.2
ENST00000592521.1
ENST00000587139.1
KIAA1328
KIAA1328
chr20_-_45981138 0.82 ENST00000446994.2
ZMYND8
zinc finger, MYND-type containing 8
chr1_-_6557156 0.82 ENST00000537245.1
PLEKHG5
pleckstrin homology domain containing, family G (with RhoGef domain) member 5
chr3_-_69062790 0.80 ENST00000540955.1
ENST00000456376.1
EOGT
EGF domain-specific O-linked N-acetylglucosamine (GlcNAc) transferase
chr19_+_10196781 0.80 ENST00000253110.11
C19orf66
chromosome 19 open reading frame 66
chr8_-_11058847 0.79 ENST00000297303.4
ENST00000416569.2
XKR6
XK, Kell blood group complex subunit-related family, member 6
chr1_-_154531095 0.79 ENST00000292211.4
UBE2Q1
ubiquitin-conjugating enzyme E2Q family member 1
chr10_+_115999089 0.77 ENST00000392982.3
VWA2
von Willebrand factor A domain containing 2
chr11_+_8704298 0.75 ENST00000531978.1
ENST00000524496.1
ENST00000532359.1
ENST00000530022.1
RPL27A
ribosomal protein L27a
chr22_+_20104947 0.74 ENST00000402752.1
RANBP1
RAN binding protein 1
chr19_+_19626531 0.72 ENST00000507754.4
NDUFA13
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 13
chr3_+_185304059 0.71 ENST00000427465.2
SENP2
SUMO1/sentrin/SMT3 specific peptidase 2
chr22_+_20105012 0.70 ENST00000331821.3
ENST00000411892.1
RANBP1
RAN binding protein 1
chr17_-_1508379 0.69 ENST00000412517.3
SLC43A2
solute carrier family 43 (amino acid system L transporter), member 2
chr1_-_154943002 0.68 ENST00000606391.1
SHC1
SHC (Src homology 2 domain containing) transforming protein 1
chr4_-_120548779 0.68 ENST00000264805.5
PDE5A
phosphodiesterase 5A, cGMP-specific
chr17_+_42081914 0.68 ENST00000293404.3
ENST00000589767.1
NAGS
N-acetylglutamate synthase
chr21_-_46707793 0.67 ENST00000331343.7
ENST00000349485.5
POFUT2
protein O-fucosyltransferase 2
chr5_-_175964366 0.64 ENST00000274811.4
RNF44
ring finger protein 44
chr21_-_46238034 0.64 ENST00000332859.6
SUMO3
small ubiquitin-like modifier 3
chr15_+_89182178 0.62 ENST00000559876.1
ISG20
interferon stimulated exonuclease gene 20kDa
chr14_-_104313824 0.59 ENST00000553739.1
ENST00000202556.9
PPP1R13B
protein phosphatase 1, regulatory subunit 13B
chr14_-_85996332 0.59 ENST00000380722.1
RP11-497E19.1
RP11-497E19.1
chr11_-_65429891 0.59 ENST00000527874.1
RELA
v-rel avian reticuloendotheliosis viral oncogene homolog A
chr22_+_20105259 0.58 ENST00000416427.1
ENST00000421656.1
ENST00000423859.1
ENST00000418705.2
RANBP1
RAN binding protein 1
chr6_-_41863098 0.58 ENST00000373006.1
USP49
ubiquitin specific peptidase 49
chr11_-_65430251 0.58 ENST00000534283.1
ENST00000527749.1
ENST00000533187.1
ENST00000525693.1
ENST00000534558.1
ENST00000532879.1
ENST00000532999.1
RELA
v-rel avian reticuloendotheliosis viral oncogene homolog A
chr3_-_69062742 0.58 ENST00000424374.1
EOGT
EGF domain-specific O-linked N-acetylglucosamine (GlcNAc) transferase
chr1_+_65613217 0.57 ENST00000545314.1
AK4
adenylate kinase 4
chr15_+_89181974 0.56 ENST00000306072.5
ISG20
interferon stimulated exonuclease gene 20kDa
chr10_+_115999004 0.56 ENST00000603594.1
VWA2
von Willebrand factor A domain containing 2
chr1_+_65613340 0.56 ENST00000546702.1
AK4
adenylate kinase 4
chr17_-_7297833 0.55 ENST00000571802.1
ENST00000576201.1
ENST00000573213.1
ENST00000324822.11
TMEM256-PLSCR3
TMEM256-PLSCR3 readthrough (NMD candidate)
chr2_+_24272576 0.55 ENST00000380986.4
ENST00000452109.1
FKBP1B
FK506 binding protein 1B, 12.6 kDa
chr13_-_52027134 0.55 ENST00000311234.4
ENST00000425000.1
ENST00000463928.1
ENST00000442263.3
ENST00000398119.2
INTS6
integrator complex subunit 6
chr15_-_43802769 0.54 ENST00000263801.3
TP53BP1
tumor protein p53 binding protein 1
chr18_-_34409116 0.54 ENST00000334295.4
TPGS2
tubulin polyglutamylase complex subunit 2
chr18_-_34408902 0.54 ENST00000593035.1
ENST00000383056.3
ENST00000588909.1
ENST00000590337.1
TPGS2
tubulin polyglutamylase complex subunit 2
chr6_+_155054459 0.53 ENST00000367178.3
ENST00000417268.1
ENST00000367186.4
SCAF8
SR-related CTD-associated factor 8
chr9_-_112083229 0.52 ENST00000374566.3
ENST00000374557.4
EPB41L4B
erythrocyte membrane protein band 4.1 like 4B
chr9_-_140115775 0.52 ENST00000391553.1
ENST00000392827.1
RNF208
ring finger protein 208
chr21_-_46237959 0.51 ENST00000397898.3
ENST00000411651.2
SUMO3
small ubiquitin-like modifier 3
chr17_+_45608430 0.50 ENST00000322157.4
NPEPPS
aminopeptidase puromycin sensitive
chr14_+_102027688 0.49 ENST00000510508.4
ENST00000359323.3
DIO3
deiodinase, iodothyronine, type III
chr8_-_116681686 0.48 ENST00000519815.1
TRPS1
trichorhinophalangeal syndrome I
chrX_+_146993648 0.48 ENST00000370470.1
FMR1
fragile X mental retardation 1
chr4_-_151936865 0.48 ENST00000535741.1
LRBA
LPS-responsive vesicle trafficking, beach and anchor containing
chr11_-_57092381 0.48 ENST00000358252.3
TNKS1BP1
tankyrase 1 binding protein 1, 182kDa
chrX_+_69674943 0.47 ENST00000542398.1
DLG3
discs, large homolog 3 (Drosophila)
chr3_+_185303962 0.46 ENST00000296257.5
SENP2
SUMO1/sentrin/SMT3 specific peptidase 2
chr8_-_124286495 0.46 ENST00000297857.2
ZHX1
zinc fingers and homeoboxes 1
chr15_+_89182156 0.46 ENST00000379224.5
ISG20
interferon stimulated exonuclease gene 20kDa
chr13_-_52026730 0.45 ENST00000420668.2
INTS6
integrator complex subunit 6
chr15_+_79166065 0.44 ENST00000559690.1
ENST00000559158.1
MORF4L1
mortality factor 4 like 1
chr3_-_48601206 0.44 ENST00000273610.3
UCN2
urocortin 2
chr3_+_14989186 0.43 ENST00000435454.1
ENST00000323373.6
NR2C2
nuclear receptor subfamily 2, group C, member 2
chr11_-_65430554 0.43 ENST00000308639.9
ENST00000406246.3
RELA
v-rel avian reticuloendotheliosis viral oncogene homolog A
chr2_+_232575128 0.42 ENST00000412128.1
PTMA
prothymosin, alpha
chr2_+_24272543 0.42 ENST00000380991.4
FKBP1B
FK506 binding protein 1B, 12.6 kDa
chr16_+_610407 0.42 ENST00000409413.3
C16orf11
chromosome 16 open reading frame 11
chr4_-_129209221 0.41 ENST00000512483.1
PGRMC2
progesterone receptor membrane component 2
chr4_-_151936416 0.41 ENST00000510413.1
ENST00000507224.1
LRBA
LPS-responsive vesicle trafficking, beach and anchor containing
chr1_-_154943212 0.40 ENST00000368445.5
ENST00000448116.2
ENST00000368449.4
SHC1
SHC (Src homology 2 domain containing) transforming protein 1
chr2_-_153573887 0.40 ENST00000493468.2
ENST00000545856.1
PRPF40A
PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae)
chr5_-_11904152 0.39 ENST00000304623.8
ENST00000458100.2
CTNND2
catenin (cadherin-associated protein), delta 2
chr11_-_46142615 0.38 ENST00000529734.1
ENST00000323180.6
PHF21A
PHD finger protein 21A
chr12_-_80328700 0.37 ENST00000550107.1
PPP1R12A
protein phosphatase 1, regulatory subunit 12A
chr6_+_32938665 0.37 ENST00000374831.4
ENST00000395289.2
BRD2
bromodomain containing 2
chr11_+_118307179 0.36 ENST00000534358.1
ENST00000531904.2
ENST00000389506.5
ENST00000354520.4
KMT2A
lysine (K)-specific methyltransferase 2A
chr15_-_70388943 0.36 ENST00000559048.1
ENST00000560939.1
ENST00000440567.3
ENST00000557907.1
ENST00000558379.1
ENST00000451782.2
ENST00000559929.1
TLE3
transducin-like enhancer of split 3 (E(sp1) homolog, Drosophila)
chr11_+_120207787 0.36 ENST00000397843.2
ENST00000356641.3
ARHGEF12
Rho guanine nucleotide exchange factor (GEF) 12
chr2_-_74667612 0.35 ENST00000305557.5
ENST00000233330.6
RTKN
rhotekin
chr16_-_30134441 0.34 ENST00000395200.1
MAPK3
mitogen-activated protein kinase 3
chr6_+_32938692 0.33 ENST00000443797.2
BRD2
bromodomain containing 2
chr1_-_39325431 0.33 ENST00000373001.3
RRAGC
Ras-related GTP binding C
chr5_-_11904100 0.32 ENST00000359640.2
CTNND2
catenin (cadherin-associated protein), delta 2
chr5_-_141030943 0.32 ENST00000522783.1
ENST00000519800.1
ENST00000435817.2
FCHSD1
FCH and double SH3 domains 1
chr7_-_91509986 0.32 ENST00000456229.1
ENST00000442961.1
ENST00000406735.2
ENST00000419292.1
ENST00000351870.3
MTERF
mitochondrial transcription termination factor
chr10_-_104001231 0.31 ENST00000370002.3
PITX3
paired-like homeodomain 3
chr22_+_47158578 0.31 ENST00000355704.3
TBC1D22A
TBC1 domain family, member 22A
chr17_-_7297519 0.31 ENST00000576362.1
ENST00000571078.1
TMEM256-PLSCR3
TMEM256-PLSCR3 readthrough (NMD candidate)
chr8_-_120685608 0.31 ENST00000427067.2
ENPP2
ectonucleotide pyrophosphatase/phosphodiesterase 2
chr7_-_91509972 0.30 ENST00000425936.1
MTERF
mitochondrial transcription termination factor
chr17_-_32906388 0.30 ENST00000357754.1
C17orf102
chromosome 17 open reading frame 102
chr12_+_3000037 0.30 ENST00000544943.1
ENST00000448120.2
TULP3
tubby like protein 3
chr9_-_34637718 0.30 ENST00000378892.1
ENST00000277010.4
SIGMAR1
sigma non-opioid intracellular receptor 1
chr6_-_29595779 0.29 ENST00000355973.3
ENST00000377012.4
GABBR1
gamma-aminobutyric acid (GABA) B receptor, 1
chrX_-_71525742 0.29 ENST00000450875.1
ENST00000417400.1
ENST00000431381.1
ENST00000445983.1
CITED1
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1
chr6_+_108881012 0.29 ENST00000343882.6
FOXO3
forkhead box O3
chr17_-_4890919 0.29 ENST00000572543.1
ENST00000381311.5
ENST00000348066.3
ENST00000358183.4
CAMTA2
calmodulin binding transcription activator 2
chr15_+_43803143 0.28 ENST00000382031.1
MAP1A
microtubule-associated protein 1A
chrX_+_37430822 0.27 ENST00000378621.3
ENST00000378619.3
LANCL3
LanC lantibiotic synthetase component C-like 3 (bacterial)
chr1_-_37980344 0.26 ENST00000448519.2
ENST00000373075.2
ENST00000373073.4
ENST00000296214.5
MEAF6
MYST/Esa1-associated factor 6
chr6_-_38607673 0.26 ENST00000481247.1
BTBD9
BTB (POZ) domain containing 9
chr6_+_108882069 0.26 ENST00000406360.1
FOXO3
forkhead box O3
chr16_+_88704978 0.26 ENST00000244241.4
IL17C
interleukin 17C
chr18_-_34408802 0.26 ENST00000590842.1
TPGS2
tubulin polyglutamylase complex subunit 2
chr12_+_58148842 0.25 ENST00000266643.5
MARCH9
membrane-associated ring finger (C3HC4) 9
chr7_-_132262060 0.25 ENST00000359827.3
PLXNA4
plexin A4
chr11_+_117049445 0.24 ENST00000324225.4
ENST00000532960.1
SIDT2
SID1 transmembrane family, member 2
chrX_+_146993534 0.24 ENST00000334557.6
ENST00000439526.2
ENST00000370475.4
FMR1
fragile X mental retardation 1
chr19_+_48972459 0.23 ENST00000427476.1
CYTH2
cytohesin 2
chr1_+_230203010 0.23 ENST00000541865.1
GALNT2
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 2 (GalNAc-T2)
chr4_-_147443043 0.23 ENST00000394059.4
ENST00000502607.1
ENST00000335472.7
ENST00000432059.2
ENST00000394062.3
SLC10A7
solute carrier family 10, member 7
chr14_+_62162258 0.22 ENST00000337138.4
ENST00000394997.1
HIF1A
hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
chrX_-_153059958 0.22 ENST00000370092.3
ENST00000217901.5
IDH3G
isocitrate dehydrogenase 3 (NAD+) gamma
chr1_+_154474689 0.22 ENST00000368482.4
TDRD10
tudor domain containing 10
chr22_+_44351419 0.22 ENST00000396202.3
SAMM50
SAMM50 sorting and assembly machinery component
chr14_-_62162541 0.22 ENST00000557544.1
HIF1A-AS1
HIF1A antisense RNA 1
chrX_-_153059811 0.22 ENST00000427365.2
ENST00000444450.1
ENST00000370093.1
IDH3G
isocitrate dehydrogenase 3 (NAD+) gamma
chr12_-_118810688 0.22 ENST00000542532.1
ENST00000392533.3
TAOK3
TAO kinase 3
chr8_+_145065705 0.21 ENST00000533044.1
GRINA
glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding)
chr14_-_77227695 0.21 ENST00000556271.1
RP11-99E15.2
RP11-99E15.2
chr11_+_10772534 0.21 ENST00000361367.2
CTR9
CTR9, Paf1/RNA polymerase II complex component
chr17_+_7211280 0.20 ENST00000419711.2
ENST00000571955.1
ENST00000573714.1
EIF5A
eukaryotic translation initiation factor 5A
chr12_-_76953513 0.20 ENST00000547540.1
OSBPL8
oxysterol binding protein-like 8
chr4_+_619386 0.20 ENST00000496514.1
PDE6B
phosphodiesterase 6B, cGMP-specific, rod, beta
chr8_-_145550337 0.20 ENST00000531896.1
DGAT1
diacylglycerol O-acyltransferase 1
chr7_+_100318423 0.19 ENST00000252723.2
EPO
erythropoietin
chr4_+_619347 0.18 ENST00000255622.6
PDE6B
phosphodiesterase 6B, cGMP-specific, rod, beta
chr15_-_74045088 0.18 ENST00000569673.1
C15orf59
chromosome 15 open reading frame 59
chr6_-_17706618 0.18 ENST00000262077.2
ENST00000537253.1
NUP153
nucleoporin 153kDa
chr1_+_53098862 0.18 ENST00000517870.1
FAM159A
family with sequence similarity 159, member A
chr20_+_44657807 0.17 ENST00000372315.1
SLC12A5
solute carrier family 12 (potassium/chloride transporter), member 5
chr20_+_35202909 0.17 ENST00000558530.1
ENST00000558028.1
ENST00000560025.1
TGIF2-C20orf24
TGIF2
TGIF2-C20orf24 readthrough
TGFB-induced factor homeobox 2
chr9_+_136243264 0.17 ENST00000371955.1
C9orf96
chromosome 9 open reading frame 96
chr1_-_85725316 0.17 ENST00000344356.5
ENST00000471115.1
C1orf52
chromosome 1 open reading frame 52
chr1_-_36851475 0.17 ENST00000373129.3
STK40
serine/threonine kinase 40
chr15_-_96590126 0.17 ENST00000561051.1
RP11-4G2.1
RP11-4G2.1
chr11_+_120110863 0.16 ENST00000543440.2
POU2F3
POU class 2 homeobox 3
chrX_+_153059608 0.16 ENST00000370087.1
SSR4
signal sequence receptor, delta
chr18_+_46065570 0.16 ENST00000591412.1
CTIF
CBP80/20-dependent translation initiation factor
chr9_-_130517522 0.16 ENST00000373274.3
ENST00000420366.1
SH2D3C
SH2 domain containing 3C
chr17_-_37382105 0.16 ENST00000333461.5
STAC2
SH3 and cysteine rich domain 2
chr1_-_99470368 0.16 ENST00000263177.4
LPPR5
Lipid phosphate phosphatase-related protein type 5
chr22_+_47158518 0.15 ENST00000337137.4
ENST00000380995.1
ENST00000407381.3
TBC1D22A
TBC1 domain family, member 22A
chr16_+_23569021 0.15 ENST00000567212.1
ENST00000567264.1
UBFD1
ubiquitin family domain containing 1
chr18_+_46065483 0.15 ENST00000382998.4
CTIF
CBP80/20-dependent translation initiation factor
chr12_-_76953453 0.15 ENST00000549570.1
OSBPL8
oxysterol binding protein-like 8
chr13_-_36871886 0.14 ENST00000491049.2
ENST00000503173.1
ENST00000239860.6
ENST00000379862.2
ENST00000239859.7
ENST00000379864.2
ENST00000510088.1
ENST00000554962.1
ENST00000511166.1
CCDC169
SOHLH2
CCDC169-SOHLH2
coiled-coil domain containing 169
spermatogenesis and oogenesis specific basic helix-loop-helix 2
CCDC169-SOHLH2 readthrough
chr16_-_56553882 0.14 ENST00000568104.1
BBS2
Bardet-Biedl syndrome 2
chr16_-_30134524 0.14 ENST00000395202.1
ENST00000395199.3
ENST00000263025.4
ENST00000322266.5
ENST00000403394.1
MAPK3
mitogen-activated protein kinase 3
chrX_-_41782249 0.14 ENST00000442742.2
ENST00000421587.2
ENST00000378166.4
ENST00000318588.9
ENST00000361962.4
CASK
calcium/calmodulin-dependent serine protein kinase (MAGUK family)
chr1_+_156863470 0.14 ENST00000338302.3
ENST00000455314.1
ENST00000292357.7
PEAR1
platelet endothelial aggregation receptor 1
chr2_-_159313214 0.14 ENST00000409889.1
ENST00000283233.5
ENST00000536771.1
CCDC148
coiled-coil domain containing 148
chr1_-_154474589 0.14 ENST00000304760.2
SHE
Src homology 2 domain containing E
chr19_-_48894104 0.13 ENST00000597017.1
KDELR1
KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1
chr1_-_85666688 0.13 ENST00000341460.5
SYDE2
synapse defective 1, Rho GTPase, homolog 2 (C. elegans)
chr15_-_52263937 0.12 ENST00000315141.5
ENST00000299601.5
LEO1
Leo1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)
chr14_+_106938440 0.12 ENST00000433371.1
ENST00000449670.1
ENST00000334298.3
LINC00221
long intergenic non-protein coding RNA 221
chr17_-_46623441 0.12 ENST00000330070.4
HOXB2
homeobox B2
chr17_-_56606664 0.12 ENST00000580844.1
SEPT4
septin 4
chr9_-_37034028 0.12 ENST00000520281.1
ENST00000446742.1
ENST00000522003.1
ENST00000523145.1
ENST00000414447.1
ENST00000377847.2
ENST00000377853.2
ENST00000377852.2
ENST00000523241.1
ENST00000520154.1
ENST00000358127.4
PAX5
paired box 5
chr6_-_31125850 0.12 ENST00000507751.1
ENST00000448162.2
ENST00000502557.1
ENST00000503420.1
ENST00000507892.1
ENST00000507226.1
ENST00000513222.1
ENST00000503934.1
ENST00000396263.2
ENST00000508683.1
ENST00000428174.1
ENST00000448141.2
ENST00000507829.1
ENST00000455279.2
ENST00000376266.5
CCHCR1
coiled-coil alpha-helical rod protein 1
chr15_+_27216530 0.12 ENST00000555083.1
GABRG3
gamma-aminobutyric acid (GABA) A receptor, gamma 3
chr14_-_51297197 0.11 ENST00000382043.4
NIN
ninein (GSK3B interacting protein)
chr17_-_56606705 0.11 ENST00000317268.3
SEPT4
septin 4
chr1_-_36851489 0.11 ENST00000373130.3
ENST00000373132.3
STK40
serine/threonine kinase 40
chr10_+_76585303 0.11 ENST00000372725.1
KAT6B
K(lysine) acetyltransferase 6B
chr12_+_120105558 0.10 ENST00000229328.5
ENST00000541640.1
PRKAB1
protein kinase, AMP-activated, beta 1 non-catalytic subunit
chr11_-_46142948 0.10 ENST00000257821.4
PHF21A
PHD finger protein 21A
chr4_+_56815102 0.10 ENST00000257287.4
CEP135
centrosomal protein 135kDa
chr7_-_15726296 0.10 ENST00000262041.5
MEOX2
mesenchyme homeobox 2
chr17_-_56606639 0.10 ENST00000579371.1
SEPT4
septin 4
chr18_-_51750948 0.09 ENST00000583046.1
ENST00000398398.2
MBD2
methyl-CpG binding domain protein 2
chr18_+_46065393 0.09 ENST00000256413.3
CTIF
CBP80/20-dependent translation initiation factor
chr4_-_129208940 0.09 ENST00000296425.5
PGRMC2
progesterone receptor membrane component 2
chr1_+_168148273 0.09 ENST00000367830.3
TIPRL
TIP41, TOR signaling pathway regulator-like (S. cerevisiae)
chr22_-_30695471 0.09 ENST00000434291.1
RP1-130H16.18
Uncharacterized protein
chr16_+_67360712 0.09 ENST00000569499.2
ENST00000329956.6
ENST00000561948.1
LRRC36
leucine rich repeat containing 36
chr20_+_44657845 0.09 ENST00000243964.3
SLC12A5
solute carrier family 12 (potassium/chloride transporter), member 5
chr2_+_232575168 0.09 ENST00000440384.1
PTMA
prothymosin, alpha
chr5_+_178986693 0.09 ENST00000437570.2
ENST00000393438.2
RUFY1
RUN and FYVE domain containing 1

Network of associatons between targets according to the STRING database.

First level regulatory network of INSM1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 5.6 GO:0051710 cytolysis by symbiont of host cells(GO:0001897) regulation of cytolysis in other organism(GO:0051710)
1.0 14.3 GO:0035290 trunk segmentation(GO:0035290) trunk neural crest cell migration(GO:0036484) ventral trunk neural crest cell migration(GO:0036486) neural crest cell migration involved in autonomic nervous system development(GO:1901166)
0.5 1.6 GO:0006117 acetaldehyde metabolic process(GO:0006117)
0.5 1.5 GO:0060489 orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490)
0.4 2.2 GO:0061343 cell adhesion involved in heart morphogenesis(GO:0061343)
0.3 1.6 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
0.3 3.1 GO:0015760 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.3 0.8 GO:1901254 modulation by host of viral RNA genome replication(GO:0044830) positive regulation of intracellular transport of viral material(GO:1901254)
0.3 2.0 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.2 2.2 GO:1902952 positive regulation of dendritic spine maintenance(GO:1902952) regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903756) negative regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903758)
0.2 1.4 GO:1902164 mRNA localization resulting in posttranscriptional regulation of gene expression(GO:0010609) regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902162) positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902164)
0.2 0.5 GO:0001544 initiation of primordial ovarian follicle growth(GO:0001544)
0.2 0.2 GO:0046832 negative regulation of nucleobase-containing compound transport(GO:0032240) negative regulation of RNA export from nucleus(GO:0046832)
0.2 0.3 GO:0060434 bronchus morphogenesis(GO:0060434)
0.2 0.5 GO:2000657 regulation of apolipoprotein binding(GO:2000656) negative regulation of apolipoprotein binding(GO:2000657)
0.1 0.6 GO:0035616 histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.1 1.1 GO:1901189 positive regulation of ephrin receptor signaling pathway(GO:1901189) positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068)
0.1 0.4 GO:0035508 positive regulation of myosin-light-chain-phosphatase activity(GO:0035508)
0.1 1.1 GO:0046940 nucleoside monophosphate phosphorylation(GO:0046940)
0.1 1.3 GO:0007161 calcium-independent cell-matrix adhesion(GO:0007161)
0.1 1.4 GO:0035457 cellular response to interferon-alpha(GO:0035457)
0.1 0.3 GO:0040040 thermosensory behavior(GO:0040040)
0.1 0.7 GO:0060282 positive regulation of oocyte development(GO:0060282)
0.1 0.2 GO:0021793 chemorepulsion of branchiomotor axon(GO:0021793)
0.1 1.0 GO:0010459 negative regulation of heart rate(GO:0010459)
0.1 1.2 GO:0035562 protein desumoylation(GO:0016926) negative regulation of chromatin binding(GO:0035562)
0.1 0.7 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.1 0.6 GO:0044154 histone H3-K14 acetylation(GO:0044154)
0.1 0.7 GO:0006526 arginine biosynthetic process(GO:0006526)
0.1 0.3 GO:0030382 sperm mitochondrion organization(GO:0030382)
0.1 0.2 GO:0038162 erythropoietin-mediated signaling pathway(GO:0038162)
0.1 0.4 GO:0006102 isocitrate metabolic process(GO:0006102)
0.1 0.3 GO:1904933 regulation of cell proliferation in midbrain(GO:1904933)
0.1 1.1 GO:0015812 gamma-aminobutyric acid transport(GO:0015812)
0.1 0.5 GO:0051549 positive regulation of keratinocyte migration(GO:0051549)
0.1 0.8 GO:0070459 prolactin secretion(GO:0070459)
0.1 0.2 GO:0051541 elastin metabolic process(GO:0051541)
0.1 0.4 GO:0032185 septin cytoskeleton organization(GO:0032185)
0.1 0.5 GO:0043401 steroid hormone mediated signaling pathway(GO:0043401)
0.0 0.3 GO:0002378 immunoglobulin biosynthetic process(GO:0002378)
0.0 1.3 GO:0005513 detection of calcium ion(GO:0005513)
0.0 0.7 GO:0036066 protein O-linked fucosylation(GO:0036066)
0.0 0.9 GO:0060252 positive regulation of glial cell proliferation(GO:0060252)
0.0 0.5 GO:0046549 retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
0.0 0.1 GO:0021569 rhombomere 3 development(GO:0021569)
0.0 0.3 GO:0071105 response to interleukin-9(GO:0071104) response to interleukin-11(GO:0071105)
0.0 1.0 GO:0016180 snRNA processing(GO:0016180)
0.0 0.3 GO:1900242 regulation of synaptic vesicle endocytosis(GO:1900242)
0.0 0.3 GO:0097396 response to interleukin-17(GO:0097396) cellular response to interleukin-17(GO:0097398)
0.0 0.1 GO:0038108 negative regulation of appetite by leptin-mediated signaling pathway(GO:0038108)
0.0 0.1 GO:2001162 regulation of histone H3-K79 methylation(GO:2001160) positive regulation of histone H3-K79 methylation(GO:2001162)
0.0 0.3 GO:0090204 protein localization to nuclear pore(GO:0090204)
0.0 0.2 GO:0006452 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.0 0.5 GO:0071481 cellular response to X-ray(GO:0071481)
0.0 0.1 GO:0098582 innate vocalization behavior(GO:0098582)
0.0 0.3 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.0 0.1 GO:0043654 recognition of apoptotic cell(GO:0043654)
0.0 1.1 GO:0007176 regulation of epidermal growth factor-activated receptor activity(GO:0007176)
0.0 0.2 GO:0045040 protein import into mitochondrial outer membrane(GO:0045040)
0.0 1.2 GO:0070911 global genome nucleotide-excision repair(GO:0070911)
0.0 0.3 GO:0036155 acylglycerol acyl-chain remodeling(GO:0036155)
0.0 0.1 GO:0001757 somite specification(GO:0001757)
0.0 0.2 GO:0033227 dsRNA transport(GO:0033227)
0.0 2.0 GO:0002181 cytoplasmic translation(GO:0002181)
0.0 0.8 GO:0035767 endothelial cell chemotaxis(GO:0035767)
0.0 2.1 GO:0043647 inositol phosphate metabolic process(GO:0043647)
0.0 1.0 GO:0046037 GMP metabolic process(GO:0046037)
0.0 2.2 GO:0006493 protein O-linked glycosylation(GO:0006493)
0.0 0.5 GO:0010800 positive regulation of peptidyl-threonine phosphorylation(GO:0010800)
0.0 0.9 GO:0001510 RNA methylation(GO:0001510)
0.0 0.7 GO:0015804 neutral amino acid transport(GO:0015804)
0.0 0.4 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0 0.5 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.6 GO:0035525 NF-kappaB p50/p65 complex(GO:0035525)
0.4 1.5 GO:0060187 cell pole(GO:0060187)
0.3 0.8 GO:1902737 dendritic filopodium(GO:1902737)
0.1 1.1 GO:0070435 Shc-EGFR complex(GO:0070435)
0.1 1.1 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.1 0.3 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
0.1 4.8 GO:0045095 keratin filament(GO:0045095)
0.1 0.3 GO:1990131 Gtr1-Gtr2 GTPase complex(GO:1990131)
0.1 0.9 GO:0032039 integrator complex(GO:0032039)
0.0 2.9 GO:0043198 dendritic shaft(GO:0043198)
0.0 0.4 GO:0070775 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 0.3 GO:0030991 intraciliary transport particle A(GO:0030991)
0.0 0.2 GO:0071256 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.0 0.4 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.0 4.0 GO:0016605 PML body(GO:0016605)
0.0 0.1 GO:0005944 phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
0.0 0.3 GO:0031594 neuromuscular junction(GO:0031594)
0.0 0.2 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.0 0.2 GO:0002116 semaphorin receptor complex(GO:0002116)
0.0 0.8 GO:0030175 filopodium(GO:0030175)
0.0 2.0 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 0.3 GO:0097227 sperm annulus(GO:0097227)
0.0 0.3 GO:0036477 somatodendritic compartment(GO:0036477)
0.0 0.3 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.2 GO:0005642 annulate lamellae(GO:0005642)
0.0 0.5 GO:0031143 pseudopodium(GO:0031143)
0.0 1.0 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 0.2 GO:0042405 nuclear inclusion body(GO:0042405)
0.0 0.5 GO:1990391 DNA repair complex(GO:1990391)
0.0 0.4 GO:0097381 photoreceptor disc membrane(GO:0097381)
0.0 0.1 GO:0034464 BBSome(GO:0034464)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 16.4 GO:0045499 chemorepellent activity(GO:0045499)
0.5 1.6 GO:0008859 exoribonuclease II activity(GO:0008859)
0.4 2.3 GO:0016262 protein N-acetylglucosaminyltransferase activity(GO:0016262)
0.4 3.1 GO:0015315 hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.2 1.0 GO:0005219 ryanodine-sensitive calcium-release channel activity(GO:0005219)
0.2 0.2 GO:0005128 erythropoietin receptor binding(GO:0005128)
0.2 2.1 GO:0071532 ankyrin repeat binding(GO:0071532)
0.2 1.1 GO:0046899 nucleoside triphosphate adenylate kinase activity(GO:0046899)
0.1 0.9 GO:0052828 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828)
0.1 1.2 GO:0070137 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.1 0.7 GO:0016774 phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.1 1.1 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.1 1.1 GO:0048408 epidermal growth factor binding(GO:0048408)
0.1 0.4 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.1 0.8 GO:0034046 poly(G) binding(GO:0034046)
0.1 0.4 GO:0051431 corticotropin-releasing hormone receptor 2 binding(GO:0051431)
0.1 0.4 GO:0045322 unmethylated CpG binding(GO:0045322)
0.1 1.2 GO:0031386 protein tag(GO:0031386)
0.1 0.5 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.1 0.5 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.1 0.3 GO:0047391 alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391)
0.1 2.9 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.1 0.3 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.1 2.0 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.1 1.1 GO:0000150 recombinase activity(GO:0000150)
0.1 0.3 GO:0050252 retinol O-fatty-acyltransferase activity(GO:0050252)
0.0 1.4 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 0.2 GO:0051033 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.0 1.1 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.0 0.1 GO:0005046 KDEL sequence binding(GO:0005046)
0.0 1.3 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 5.8 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.3 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.0 0.3 GO:0050693 LBD domain binding(GO:0050693)
0.0 0.5 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.8 GO:0071889 14-3-3 protein binding(GO:0071889)
0.0 0.1 GO:0050815 phosphoserine binding(GO:0050815)
0.0 0.8 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 0.3 GO:0008417 fucosyltransferase activity(GO:0008417)
0.0 0.3 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)
0.0 1.7 GO:0002039 p53 binding(GO:0002039)
0.0 0.5 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.4 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.9 GO:0008173 RNA methyltransferase activity(GO:0008173)
0.0 0.6 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 0.7 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.0 0.7 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.2 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.2 GO:0017070 U6 snRNA binding(GO:0017070)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 14.7 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 1.6 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.0 1.8 SIG IL4RECEPTOR IN B LYPHOCYTES Genes related to IL4 rceptor signaling in B lymphocytes
0.0 1.2 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 1.1 PID PS1 PATHWAY Presenilin action in Notch and Wnt signaling
0.0 2.0 PID E2F PATHWAY E2F transcription factor network
0.0 0.5 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 0.4 PID ARF 3PATHWAY Arf1 pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.6 REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL Genes involved in NF-kB is activated and signals survival
0.1 1.1 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.1 2.4 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 1.2 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.0 1.1 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.9 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 3.1 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.5 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.0 0.5 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0 0.5 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 0.4 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 2.0 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 2.2 REACTOME LATE PHASE OF HIV LIFE CYCLE Genes involved in Late Phase of HIV Life Cycle
0.0 0.7 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane