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SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for IRF6_IRF4_IRF5

Z-value: 1.62

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Transcription factors associated with IRF6_IRF4_IRF5

Gene Symbol Gene ID Gene Info
IRF6
ENSG00000117595.6 interferon regulatory factor 6
IRF4
ENSG00000137265.10 interferon regulatory factor 4
IRF5
ENSG00000128604.14 interferon regulatory factor 5

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
IRF6hg19_v2_chr1_-_209975494_2099755110.381.0e-01Click!
IRF4hg19_v2_chr6_+_391739_391759-0.302.0e-01Click!
IRF5hg19_v2_chr7_+_128577972_128578047-0.272.5e-01Click!

Activity profile of IRF6_IRF4_IRF5 motif

Sorted Z-values of IRF6_IRF4_IRF5 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr11_-_321050 8.08 ENST00000399808.4
IFITM3
interferon induced transmembrane protein 3
chr1_-_59043166 4.99 ENST00000371225.2
TACSTD2
tumor-associated calcium signal transducer 2
chr11_-_118134997 4.84 ENST00000278937.2
MPZL2
myelin protein zero-like 2
chr11_-_118135160 4.78 ENST00000438295.2
MPZL2
myelin protein zero-like 2
chr19_+_16254488 4.57 ENST00000588246.1
ENST00000593031.1
HSH2D
hematopoietic SH2 domain containing
chr21_+_42792442 4.52 ENST00000398600.2
MX1
myxovirus (influenza virus) resistance 1, interferon-inducible protein p78 (mouse)
chr21_+_42798094 4.22 ENST00000398598.3
ENST00000455164.2
ENST00000424365.1
MX1
myxovirus (influenza virus) resistance 1, interferon-inducible protein p78 (mouse)
chr11_-_615942 3.64 ENST00000397562.3
ENST00000330243.5
ENST00000397570.1
ENST00000397574.2
IRF7
interferon regulatory factor 7
chr9_-_32526184 3.28 ENST00000545044.1
ENST00000379868.1
DDX58
DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
chr11_-_321340 3.25 ENST00000526811.1
IFITM3
interferon induced transmembrane protein 3
chr9_-_32526299 3.04 ENST00000379882.1
ENST00000379883.2
DDX58
DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
chr11_+_5710919 3.01 ENST00000379965.3
ENST00000425490.1
TRIM22
tripartite motif containing 22
chr11_+_5711010 3.01 ENST00000454828.1
TRIM22
tripartite motif containing 22
chr17_+_6659153 2.98 ENST00000441631.1
ENST00000438512.1
ENST00000346752.4
ENST00000361842.3
XAF1
XIAP associated factor 1
chr10_-_10836919 2.60 ENST00000602763.1
ENST00000415590.2
ENST00000434919.2
SFTA1P
surfactant associated 1, pseudogene
chr21_+_42733870 2.46 ENST00000330714.3
ENST00000436410.1
ENST00000435611.1
MX2
myxovirus (influenza virus) resistance 2 (mouse)
chr21_+_42798124 2.43 ENST00000417963.1
MX1
myxovirus (influenza virus) resistance 1, interferon-inducible protein p78 (mouse)
chr17_-_7164410 2.30 ENST00000574070.1
CLDN7
claudin 7
chr19_+_10196981 2.18 ENST00000591813.1
C19orf66
chromosome 19 open reading frame 66
chr11_-_57335280 2.08 ENST00000287156.4
UBE2L6
ubiquitin-conjugating enzyme E2L 6
chr21_+_42798158 2.08 ENST00000441677.1
MX1
myxovirus (influenza virus) resistance 1, interferon-inducible protein p78 (mouse)
chr21_+_42797958 2.02 ENST00000419044.1
MX1
myxovirus (influenza virus) resistance 1, interferon-inducible protein p78 (mouse)
chr17_+_25958174 1.95 ENST00000313648.6
ENST00000577392.1
ENST00000584661.1
ENST00000413914.2
LGALS9
lectin, galactoside-binding, soluble, 9
chr3_-_122283100 1.89 ENST00000492382.1
ENST00000462315.1
PARP9
poly (ADP-ribose) polymerase family, member 9
chr3_-_122283079 1.76 ENST00000471785.1
ENST00000466126.1
PARP9
poly (ADP-ribose) polymerase family, member 9
chr3_-_122283424 1.75 ENST00000477522.2
ENST00000360356.2
PARP9
poly (ADP-ribose) polymerase family, member 9
chr10_-_10836865 1.74 ENST00000446372.2
SFTA1P
surfactant associated 1, pseudogene
chrM_+_10053 1.74 ENST00000361227.2
MT-ND3
mitochondrially encoded NADH dehydrogenase 3
chr2_-_7005785 1.72 ENST00000256722.5
ENST00000404168.1
ENST00000458098.1
CMPK2
cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial
chr17_-_39677971 1.56 ENST00000393976.2
KRT15
keratin 15
chr15_+_41136734 1.44 ENST00000568580.1
SPINT1
serine peptidase inhibitor, Kunitz type 1
chr11_-_615570 1.42 ENST00000525445.1
ENST00000348655.6
ENST00000397566.1
IRF7
interferon regulatory factor 7
chr11_+_130029457 1.36 ENST00000278742.5
ST14
suppression of tumorigenicity 14 (colon carcinoma)
chr15_+_74287035 1.35 ENST00000395132.2
ENST00000268059.6
ENST00000354026.6
ENST00000268058.3
ENST00000565898.1
ENST00000569477.1
ENST00000569965.1
ENST00000567543.1
ENST00000436891.3
ENST00000435786.2
ENST00000564428.1
ENST00000359928.4
PML
promyelocytic leukemia
chr14_+_94577074 1.33 ENST00000444961.1
ENST00000448882.1
ENST00000557098.1
ENST00000554800.1
ENST00000556544.1
ENST00000298902.5
ENST00000555819.1
ENST00000557634.1
ENST00000555744.1
IFI27
interferon, alpha-inducible protein 27
chr15_+_41136586 1.30 ENST00000431806.1
SPINT1
serine peptidase inhibitor, Kunitz type 1
chr1_+_948803 1.22 ENST00000379389.4
ISG15
ISG15 ubiquitin-like modifier
chr9_-_21995300 1.20 ENST00000498628.2
CDKN2A
cyclin-dependent kinase inhibitor 2A
chr13_-_43566301 1.19 ENST00000398762.3
ENST00000313640.7
ENST00000313624.7
EPSTI1
epithelial stromal interaction 1 (breast)
chr10_+_91061712 1.16 ENST00000371826.3
IFIT2
interferon-induced protein with tetratricopeptide repeats 2
chr9_-_100881466 1.16 ENST00000341469.2
ENST00000342043.3
ENST00000375098.3
TRIM14
tripartite motif containing 14
chr7_-_20256965 1.15 ENST00000400331.5
ENST00000332878.4
MACC1
metastasis associated in colon cancer 1
chr17_+_6659354 1.14 ENST00000574907.1
XAF1
XIAP associated factor 1
chr15_+_74287118 1.14 ENST00000563500.1
PML
promyelocytic leukemia
chr4_+_69917078 1.10 ENST00000502942.1
UGT2B7
UDP glucuronosyltransferase 2 family, polypeptide B7
chr16_+_28962128 1.09 ENST00000564978.1
ENST00000320805.4
NFATC2IP
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 interacting protein
chr1_+_86889769 1.08 ENST00000370565.4
CLCA2
chloride channel accessory 2
chr3_+_187086120 1.07 ENST00000259030.2
RTP4
receptor (chemosensory) transporter protein 4
chr11_+_65554493 1.07 ENST00000335987.3
OVOL1
ovo-like zinc finger 1
chr3_-_182880541 1.01 ENST00000470251.1
ENST00000265598.3
LAMP3
lysosomal-associated membrane protein 3
chr4_+_144258288 1.01 ENST00000514639.1
GAB1
GRB2-associated binding protein 1
chrM_+_9207 0.98 ENST00000362079.2
MT-CO3
mitochondrially encoded cytochrome c oxidase III
chr3_-_146262365 0.97 ENST00000448787.2
PLSCR1
phospholipid scramblase 1
chrX_+_23801280 0.97 ENST00000379251.3
ENST00000379253.3
ENST00000379254.1
ENST00000379270.4
SAT1
spermidine/spermine N1-acetyltransferase 1
chr3_-_146262352 0.97 ENST00000462666.1
PLSCR1
phospholipid scramblase 1
chr4_+_144258021 0.96 ENST00000262994.4
GAB1
GRB2-associated binding protein 1
chr10_+_75668916 0.91 ENST00000481390.1
PLAU
plasminogen activator, urokinase
chr3_+_118892411 0.90 ENST00000479520.1
ENST00000494855.1
UPK1B
uroplakin 1B
chr3_+_122283064 0.86 ENST00000296161.4
DTX3L
deltex 3-like (Drosophila)
chr2_+_7017796 0.85 ENST00000382040.3
RSAD2
radical S-adenosyl methionine domain containing 2
chr12_-_56753858 0.85 ENST00000314128.4
ENST00000557235.1
ENST00000418572.2
STAT2
signal transducer and activator of transcription 2, 113kDa
chr7_-_138794394 0.83 ENST00000242351.5
ENST00000471652.1
ZC3HAV1
zinc finger CCCH-type, antiviral 1
chr3_+_122283175 0.82 ENST00000383661.3
DTX3L
deltex 3-like (Drosophila)
chr19_-_17516449 0.81 ENST00000252593.6
BST2
bone marrow stromal cell antigen 2
chr22_-_31688381 0.79 ENST00000487265.2
PIK3IP1
phosphoinositide-3-kinase interacting protein 1
chr2_-_37384175 0.79 ENST00000411537.2
ENST00000233057.4
ENST00000395127.2
ENST00000390013.3
EIF2AK2
eukaryotic translation initiation factor 2-alpha kinase 2
chr2_-_163175133 0.78 ENST00000421365.2
ENST00000263642.2
IFIH1
interferon induced with helicase C domain 1
chr1_-_159915386 0.74 ENST00000361509.3
ENST00000368094.1
IGSF9
immunoglobulin superfamily, member 9
chr9_+_112542572 0.74 ENST00000374530.3
PALM2-AKAP2
PALM2-AKAP2 readthrough
chr20_-_62203808 0.74 ENST00000467148.1
HELZ2
helicase with zinc finger 2, transcriptional coactivator
chr19_+_10196781 0.74 ENST00000253110.11
C19orf66
chromosome 19 open reading frame 66
chr3_+_118892362 0.73 ENST00000497685.1
ENST00000264234.3
UPK1B
uroplakin 1B
chr11_+_32851487 0.72 ENST00000257836.3
PRRG4
proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)
chr19_+_12273866 0.72 ENST00000425827.1
ENST00000439995.1
ENST00000343979.4
ENST00000398616.2
ENST00000418338.1
ZNF136
zinc finger protein 136
chr3_-_146262428 0.71 ENST00000486631.1
PLSCR1
phospholipid scramblase 1
chr3_-_146262637 0.71 ENST00000472349.1
ENST00000342435.4
PLSCR1
phospholipid scramblase 1
chr18_-_59561417 0.71 ENST00000591306.1
RNF152
ring finger protein 152
chr19_-_53193731 0.70 ENST00000598536.1
ENST00000594682.2
ENST00000601257.1
ZNF83
zinc finger protein 83
chr15_-_30114231 0.69 ENST00000356107.6
ENST00000545208.2
TJP1
tight junction protein 1
chr22_-_31688431 0.69 ENST00000402249.3
ENST00000443175.1
ENST00000215912.5
ENST00000441972.1
PIK3IP1
phosphoinositide-3-kinase interacting protein 1
chr3_+_44771088 0.66 ENST00000396048.2
ZNF501
zinc finger protein 501
chr9_+_112542591 0.65 ENST00000483909.1
ENST00000314527.4
ENST00000413420.1
ENST00000302798.7
ENST00000555236.1
ENST00000510514.5
PALM2
PALM2-AKAP2
AKAP2
paralemmin 2
PALM2-AKAP2 readthrough
A kinase (PRKA) anchor protein 2
chr12_-_50616382 0.64 ENST00000552783.1
LIMA1
LIM domain and actin binding 1
chr15_+_74287009 0.64 ENST00000395135.3
PML
promyelocytic leukemia
chr5_-_95297534 0.57 ENST00000513343.1
ENST00000431061.2
ELL2
elongation factor, RNA polymerase II, 2
chr5_-_95297678 0.55 ENST00000237853.4
ELL2
elongation factor, RNA polymerase II, 2
chr2_+_7005959 0.55 ENST00000442639.1
RSAD2
radical S-adenosyl methionine domain containing 2
chr2_-_191878874 0.54 ENST00000392322.3
ENST00000392323.2
ENST00000424722.1
ENST00000361099.3
STAT1
signal transducer and activator of transcription 1, 91kDa
chr2_-_191878681 0.54 ENST00000409465.1
STAT1
signal transducer and activator of transcription 1, 91kDa
chr12_+_113344582 0.54 ENST00000202917.5
ENST00000445409.2
ENST00000452357.2
OAS1
2'-5'-oligoadenylate synthetase 1, 40/46kDa
chr11_-_57334732 0.53 ENST00000526659.1
ENST00000527022.1
UBE2L6
ubiquitin-conjugating enzyme E2L 6
chr17_+_18380051 0.52 ENST00000581545.1
ENST00000582333.1
ENST00000328114.6
ENST00000412421.2
ENST00000583322.1
ENST00000584941.1
LGALS9C
lectin, galactoside-binding, soluble, 9C
chr1_+_210111534 0.52 ENST00000422431.1
ENST00000534859.1
ENST00000399639.2
ENST00000537238.1
SYT14
synaptotagmin XIV
chr4_+_144257915 0.50 ENST00000262995.4
GAB1
GRB2-associated binding protein 1
chr19_-_9649303 0.49 ENST00000253115.2
ZNF426
zinc finger protein 426
chr2_+_85811525 0.49 ENST00000306384.4
VAMP5
vesicle-associated membrane protein 5
chr15_+_83478370 0.49 ENST00000286760.4
WHAMM
WAS protein homolog associated with actin, golgi membranes and microtubules
chr6_+_43738444 0.47 ENST00000324450.6
ENST00000417285.2
ENST00000413642.3
ENST00000372055.4
ENST00000482630.2
ENST00000425836.2
ENST00000372064.4
ENST00000372077.4
ENST00000519767.1
VEGFA
vascular endothelial growth factor A
chr19_-_9649253 0.46 ENST00000593003.1
ZNF426
zinc finger protein 426
chr2_-_74753332 0.46 ENST00000451518.1
ENST00000404568.3
DQX1
DEAQ box RNA-dependent ATPase 1
chr1_+_78354330 0.46 ENST00000440324.1
NEXN
nexilin (F actin binding protein)
chr12_+_75874580 0.46 ENST00000456650.3
GLIPR1
GLI pathogenesis-related 1
chr11_+_128563652 0.45 ENST00000527786.2
FLI1
Fli-1 proto-oncogene, ETS transcription factor
chrX_-_30877837 0.45 ENST00000378930.3
TAB3
TGF-beta activated kinase 1/MAP3K7 binding protein 3
chr15_+_90895471 0.43 ENST00000354377.3
ENST00000379090.5
ZNF774
zinc finger protein 774
chr6_+_32937083 0.43 ENST00000456339.1
BRD2
bromodomain containing 2
chr17_+_41363854 0.42 ENST00000588693.1
ENST00000588659.1
ENST00000541594.1
ENST00000536052.1
ENST00000331615.3
TMEM106A
transmembrane protein 106A
chr3_+_154797877 0.42 ENST00000462745.1
ENST00000493237.1
MME
membrane metallo-endopeptidase
chr12_+_75874460 0.42 ENST00000266659.3
GLIPR1
GLI pathogenesis-related 1
chr6_-_137365402 0.42 ENST00000541547.1
IL20RA
interleukin 20 receptor, alpha
chr12_-_51663682 0.42 ENST00000603838.1
SMAGP
small cell adhesion glycoprotein
chr4_+_89378261 0.41 ENST00000264350.3
HERC5
HECT and RLD domain containing E3 ubiquitin protein ligase 5
chr1_-_160990886 0.40 ENST00000537746.1
F11R
F11 receptor
chr2_-_74753305 0.39 ENST00000393951.2
DQX1
DEAQ box RNA-dependent ATPase 1
chr6_+_53794780 0.38 ENST00000505762.1
ENST00000511369.1
ENST00000431554.2
MLIP
RP11-411K7.1
muscular LMNA-interacting protein
RP11-411K7.1
chr10_+_24528108 0.38 ENST00000438429.1
KIAA1217
KIAA1217
chr10_+_91174314 0.36 ENST00000371795.4
IFIT5
interferon-induced protein with tetratricopeptide repeats 5
chr5_-_133706695 0.36 ENST00000521755.1
ENST00000523054.1
ENST00000435240.2
ENST00000609654.1
ENST00000536186.1
ENST00000609383.1
CDKL3
cyclin-dependent kinase-like 3
chr20_+_20033158 0.36 ENST00000340348.6
ENST00000377309.2
ENST00000389656.3
ENST00000377306.1
ENST00000245957.5
ENST00000377303.2
ENST00000475466.1
C20orf26
chromosome 20 open reading frame 26
chr17_-_40264692 0.36 ENST00000591220.1
ENST00000251642.3
DHX58
DEXH (Asp-Glu-X-His) box polypeptide 58
chr8_+_13424352 0.36 ENST00000297324.4
C8orf48
chromosome 8 open reading frame 48
chr5_+_140772381 0.35 ENST00000398604.2
PCDHGA8
protocadherin gamma subfamily A, 8
chr22_+_36044411 0.35 ENST00000409652.4
APOL6
apolipoprotein L, 6
chr1_-_25558984 0.35 ENST00000236273.4
SYF2
SYF2 pre-mRNA-splicing factor
chr12_+_46123682 0.34 ENST00000422737.1
ARID2
AT rich interactive domain 2 (ARID, RFX-like)
chr8_+_39972170 0.34 ENST00000521257.1
RP11-359E19.2
RP11-359E19.2
chr17_+_7387677 0.34 ENST00000322644.6
POLR2A
polymerase (RNA) II (DNA directed) polypeptide A, 220kDa
chr7_+_70229899 0.34 ENST00000443672.1
AUTS2
autism susceptibility candidate 2
chr12_+_75874984 0.33 ENST00000550491.1
GLIPR1
GLI pathogenesis-related 1
chr2_-_55920952 0.33 ENST00000447944.2
PNPT1
polyribonucleotide nucleotidyltransferase 1
chr17_+_40118773 0.33 ENST00000472031.1
CNP
2',3'-cyclic nucleotide 3' phosphodiesterase
chr12_-_51663728 0.33 ENST00000603864.1
ENST00000605426.1
SMAGP
small cell adhesion glycoprotein
chr10_+_121410882 0.33 ENST00000369085.3
BAG3
BCL2-associated athanogene 3
chr4_+_144303093 0.33 ENST00000505913.1
GAB1
GRB2-associated binding protein 1
chr3_-_180707306 0.33 ENST00000479269.1
DNAJC19
DnaJ (Hsp40) homolog, subfamily C, member 19
chr6_-_137366096 0.32 ENST00000316649.5
ENST00000367746.3
IL20RA
interleukin 20 receptor, alpha
chr11_-_126138808 0.32 ENST00000332118.6
ENST00000532259.1
SRPR
signal recognition particle receptor (docking protein)
chr12_+_14518598 0.32 ENST00000261168.4
ENST00000538511.1
ENST00000545723.1
ENST00000543189.1
ENST00000536444.1
ATF7IP
activating transcription factor 7 interacting protein
chr12_+_62654119 0.32 ENST00000353364.3
ENST00000549523.1
ENST00000280377.5
USP15
ubiquitin specific peptidase 15
chr7_+_18330035 0.32 ENST00000413509.2
HDAC9
histone deacetylase 9
chr7_-_100895414 0.31 ENST00000435848.1
ENST00000474120.1
FIS1
fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae)
chr6_-_48036363 0.31 ENST00000543600.1
ENST00000398738.2
ENST00000339488.4
PTCHD4
patched domain containing 4
chr6_-_137366163 0.31 ENST00000367748.1
IL20RA
interleukin 20 receptor, alpha
chr21_-_34914394 0.31 ENST00000361093.5
ENST00000381815.4
GART
phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase
chr12_+_113376157 0.31 ENST00000228928.7
OAS3
2'-5'-oligoadenylate synthetase 3, 100kDa
chr1_-_25558963 0.30 ENST00000354361.3
SYF2
SYF2 pre-mRNA-splicing factor
chr7_+_18535893 0.30 ENST00000432645.2
ENST00000441542.2
HDAC9
histone deacetylase 9
chr13_+_103498143 0.28 ENST00000535557.1
ERCC5
excision repair cross-complementing rodent repair deficiency, complementation group 5
chr17_-_76778339 0.28 ENST00000591455.1
ENST00000446868.3
ENST00000361101.4
ENST00000589296.1
CYTH1
cytohesin 1
chr17_-_20370847 0.27 ENST00000423676.3
ENST00000324290.5
LGALS9B
lectin, galactoside-binding, soluble, 9B
chr19_-_4723761 0.27 ENST00000597849.1
ENST00000598800.1
ENST00000602161.1
ENST00000597726.1
ENST00000601130.1
ENST00000262960.9
DPP9
dipeptidyl-peptidase 9
chr6_+_126070726 0.27 ENST00000368364.3
HEY2
hes-related family bHLH transcription factor with YRPW motif 2
chr9_-_21995249 0.27 ENST00000494262.1
CDKN2A
cyclin-dependent kinase inhibitor 2A
chr1_-_54355430 0.26 ENST00000371399.1
ENST00000072644.1
ENST00000412288.1
YIPF1
Yip1 domain family, member 1
chr5_-_115890554 0.26 ENST00000509665.1
SEMA6A
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
chr19_+_18942761 0.26 ENST00000599848.1
UPF1
UPF1 regulator of nonsense transcripts homolog (yeast)
chr22_-_31885727 0.26 ENST00000330125.5
ENST00000344710.5
ENST00000397518.1
EIF4ENIF1
eukaryotic translation initiation factor 4E nuclear import factor 1
chr1_-_52344416 0.25 ENST00000544028.1
NRD1
nardilysin (N-arginine dibasic convertase)
chr8_-_116680833 0.25 ENST00000220888.5
TRPS1
trichorhinophalangeal syndrome I
chr7_+_151038850 0.25 ENST00000355851.4
ENST00000566856.1
ENST00000470229.1
NUB1
negative regulator of ubiquitin-like proteins 1
chr18_+_42260861 0.25 ENST00000282030.5
SETBP1
SET binding protein 1
chr12_-_51663959 0.25 ENST00000604188.1
ENST00000398453.3
SMAGP
small cell adhesion glycoprotein
chr17_-_54991395 0.25 ENST00000316881.4
TRIM25
tripartite motif containing 25
chr6_+_89791507 0.24 ENST00000354922.3
PNRC1
proline-rich nuclear receptor coactivator 1
chr18_-_812517 0.24 ENST00000584307.1
YES1
v-yes-1 Yamaguchi sarcoma viral oncogene homolog 1
chr11_-_2162468 0.23 ENST00000434045.2
IGF2
insulin-like growth factor 2 (somatomedin A)
chr6_-_91296602 0.22 ENST00000369325.3
ENST00000369327.3
MAP3K7
mitogen-activated protein kinase kinase kinase 7
chr17_-_7387524 0.22 ENST00000311403.4
ZBTB4
zinc finger and BTB domain containing 4
chr19_+_41222998 0.22 ENST00000263370.2
ITPKC
inositol-trisphosphate 3-kinase C
chr19_+_18942720 0.22 ENST00000262803.5
UPF1
UPF1 regulator of nonsense transcripts homolog (yeast)
chr1_-_52344471 0.22 ENST00000352171.7
ENST00000354831.7
NRD1
nardilysin (N-arginine dibasic convertase)
chr2_+_120770686 0.22 ENST00000331393.4
ENST00000443124.1
EPB41L5
erythrocyte membrane protein band 4.1 like 5
chr20_-_47894936 0.22 ENST00000371754.4
ZNFX1
zinc finger, NFX1-type containing 1
chr12_+_8850277 0.21 ENST00000539923.1
ENST00000537189.1
RIMKLB
ribosomal modification protein rimK-like family member B
chr14_-_103989033 0.21 ENST00000553878.1
ENST00000557530.1
CKB
creatine kinase, brain
chr17_-_26903900 0.21 ENST00000395319.3
ENST00000581807.1
ENST00000584086.1
ENST00000395321.2
ALDOC
aldolase C, fructose-bisphosphate
chr10_+_91174486 0.21 ENST00000416601.1
IFIT5
interferon-induced protein with tetratricopeptide repeats 5
chr2_+_68961934 0.21 ENST00000409202.3
ARHGAP25
Rho GTPase activating protein 25
chr1_-_54411255 0.21 ENST00000371377.3
HSPB11
heat shock protein family B (small), member 11
chr18_-_812231 0.21 ENST00000314574.4
YES1
v-yes-1 Yamaguchi sarcoma viral oncogene homolog 1
chr17_-_54991369 0.21 ENST00000537230.1
TRIM25
tripartite motif containing 25
chr14_-_23564320 0.20 ENST00000605057.1
ACIN1
apoptotic chromatin condensation inducer 1
chr15_-_30113676 0.20 ENST00000400011.2
TJP1
tight junction protein 1
chr10_+_71562180 0.20 ENST00000517713.1
ENST00000522165.1
ENST00000520133.1
COL13A1
collagen, type XIII, alpha 1
chr11_-_2162162 0.20 ENST00000381389.1
IGF2
insulin-like growth factor 2 (somatomedin A)
chr9_+_109685630 0.20 ENST00000451160.2
RP11-508N12.4
Uncharacterized protein
chr2_-_106810783 0.19 ENST00000283148.7
UXS1
UDP-glucuronate decarboxylase 1
chr2_-_106810742 0.19 ENST00000409501.3
ENST00000428048.2
ENST00000441952.1
ENST00000457835.1
ENST00000540130.1
UXS1
UDP-glucuronate decarboxylase 1
chr4_-_83295296 0.19 ENST00000507010.1
ENST00000503822.1
HNRNPD
heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa)
chr12_-_62653903 0.19 ENST00000552075.1
FAM19A2
family with sequence similarity 19 (chemokine (C-C motif)-like), member A2
chr2_+_68961905 0.18 ENST00000295381.3
ARHGAP25
Rho GTPase activating protein 25
chr2_+_217277271 0.18 ENST00000425815.1
SMARCAL1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1
chr3_-_142166796 0.18 ENST00000392981.2
XRN1
5'-3' exoribonuclease 1
chr12_-_51664058 0.18 ENST00000605627.1
SMAGP
small cell adhesion glycoprotein
chr10_+_129535441 0.18 ENST00000388920.4
FOXI2
forkhead box I2
chr10_+_114710516 0.18 ENST00000542695.1
ENST00000346198.4
TCF7L2
transcription factor 7-like 2 (T-cell specific, HMG-box)
chr1_-_224033596 0.17 ENST00000391878.2
ENST00000343537.7
TP53BP2
tumor protein p53 binding protein, 2
chr12_+_70133152 0.17 ENST00000550536.1
ENST00000362025.5
RAB3IP
RAB3A interacting protein
chr6_-_100016678 0.17 ENST00000523799.1
ENST00000520429.1
CCNC
cyclin C
chr3_-_142166846 0.17 ENST00000463916.1
ENST00000544157.1
XRN1
5'-3' exoribonuclease 1

Network of associatons between targets according to the STRING database.

First level regulatory network of IRF6_IRF4_IRF5

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.8 7.1 GO:0034344 type III interferon production(GO:0034343) regulation of type III interferon production(GO:0034344)
1.0 5.1 GO:2000110 negative regulation of macrophage apoptotic process(GO:2000110)
0.8 17.7 GO:0003373 dynamin polymerization involved in membrane fission(GO:0003373) dynamin polymerization involved in mitochondrial fission(GO:0003374)
0.7 2.0 GO:0002519 natural killer cell tolerance induction(GO:0002519)
0.5 6.3 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
0.5 5.0 GO:0090191 negative regulation of branching involved in ureteric bud morphogenesis(GO:0090191)
0.5 15.1 GO:0035455 response to interferon-alpha(GO:0035455)
0.4 1.7 GO:0009138 pyrimidine nucleoside diphosphate metabolic process(GO:0009138)
0.4 4.6 GO:0051902 negative regulation of mitochondrial depolarization(GO:0051902)
0.4 3.1 GO:0030578 PML body organization(GO:0030578)
0.4 4.2 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.3 1.0 GO:0032918 polyamine acetylation(GO:0032917) spermidine acetylation(GO:0032918)
0.3 1.5 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.3 1.4 GO:0034154 toll-like receptor 7 signaling pathway(GO:0034154)
0.3 1.1 GO:0046725 negative regulation by virus of viral protein levels in host cell(GO:0046725) negative regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072308)
0.3 2.7 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659) regulation of isomerase activity(GO:0010911) positive regulation of isomerase activity(GO:0010912) regulation of DNA topoisomerase (ATP-hydrolyzing) activity(GO:2000371) positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity(GO:2000373)
0.3 1.1 GO:1901994 negative regulation of meiotic cell cycle phase transition(GO:1901994)
0.2 0.9 GO:2000097 regulation of smooth muscle cell-matrix adhesion(GO:2000097)
0.2 0.9 GO:1901350 cell-cell signaling involved in cell-cell junction organization(GO:1901350)
0.2 1.4 GO:0060672 epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
0.2 4.5 GO:0035456 response to interferon-beta(GO:0035456)
0.2 0.5 GO:1903572 regulation of protein kinase D signaling(GO:1903570) positive regulation of protein kinase D signaling(GO:1903572)
0.1 2.7 GO:0060670 branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.1 0.3 GO:0060948 cardiac vascular smooth muscle cell development(GO:0060948)
0.1 0.4 GO:0033320 UDP-D-xylose metabolic process(GO:0033319) UDP-D-xylose biosynthetic process(GO:0033320)
0.1 1.5 GO:0035986 senescence-associated heterochromatin focus assembly(GO:0035986)
0.1 0.5 GO:0000294 nuclear-transcribed mRNA catabolic process, endonucleolytic cleavage-dependent decay(GO:0000294)
0.1 0.3 GO:0001172 transcription, RNA-templated(GO:0001172)
0.1 0.3 GO:1904578 response to thapsigargin(GO:1904578) cellular response to thapsigargin(GO:1904579)
0.1 0.3 GO:0006429 leucyl-tRNA aminoacylation(GO:0006429)
0.1 0.3 GO:1990828 response to putrescine(GO:1904585) cellular response to putrescine(GO:1904586) hepatocyte dedifferentiation(GO:1990828)
0.1 0.3 GO:0098582 innate vocalization behavior(GO:0098582)
0.1 0.3 GO:0035616 histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.1 0.4 GO:0039534 negative regulation of MDA-5 signaling pathway(GO:0039534)
0.1 0.4 GO:0071409 cellular response to cycloheximide(GO:0071409)
0.1 0.7 GO:0071492 cellular response to UV-A(GO:0071492)
0.1 5.3 GO:0070206 protein trimerization(GO:0070206)
0.1 2.9 GO:0035728 response to hepatocyte growth factor(GO:0035728)
0.1 0.2 GO:0006382 adenosine to inosine editing(GO:0006382) IDP metabolic process(GO:0046707) IDP catabolic process(GO:0046709)
0.1 11.8 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.4 GO:2000467 positive regulation of glycogen (starch) synthase activity(GO:2000467)
0.0 0.1 GO:0060733 regulation of eIF2 alpha phosphorylation by amino acid starvation(GO:0060733) regulation of translational initiation in response to starvation(GO:0071262) positive regulation of translational initiation in response to starvation(GO:0071264)
0.0 0.1 GO:0006869 lipid transport(GO:0006869) lipid localization(GO:0010876)
0.0 1.1 GO:0052695 cellular glucuronidation(GO:0052695)
0.0 1.4 GO:0032463 negative regulation of protein homooligomerization(GO:0032463)
0.0 0.2 GO:0007509 mesoderm migration involved in gastrulation(GO:0007509)
0.0 0.7 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.0 1.0 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0 1.8 GO:0010390 histone monoubiquitination(GO:0010390)
0.0 0.6 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.0 1.1 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0 1.2 GO:0032897 negative regulation of viral transcription(GO:0032897)
0.0 0.5 GO:1902187 negative regulation of viral release from host cell(GO:1902187)
0.0 1.8 GO:0046825 regulation of protein export from nucleus(GO:0046825)
0.0 0.5 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.0 0.2 GO:0030644 cellular chloride ion homeostasis(GO:0030644)
0.0 0.2 GO:0060982 coronary artery morphogenesis(GO:0060982)
0.0 0.1 GO:0032242 regulation of nucleoside transport(GO:0032242) positive regulation of necroptotic process(GO:0060545)
0.0 0.2 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.0 0.3 GO:0006189 brainstem development(GO:0003360) 'de novo' IMP biosynthetic process(GO:0006189)
0.0 0.1 GO:1904977 lymphatic endothelial cell migration(GO:1904977)
0.0 0.6 GO:0090527 actin filament reorganization(GO:0090527)
0.0 0.6 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.0 0.1 GO:0030451 regulation of complement activation, alternative pathway(GO:0030451) negative regulation of complement activation, alternative pathway(GO:0045957)
0.0 0.1 GO:0036269 swimming behavior(GO:0036269)
0.0 0.2 GO:0030263 apoptotic chromosome condensation(GO:0030263)
0.0 0.3 GO:0010225 response to UV-C(GO:0010225)
0.0 1.1 GO:0045124 regulation of bone resorption(GO:0045124)
0.0 0.8 GO:0090140 regulation of mitochondrial fission(GO:0090140)
0.0 0.4 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.0 0.1 GO:0048250 mitochondrial iron ion transport(GO:0048250)
0.0 1.3 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 0.1 GO:0010587 miRNA catabolic process(GO:0010587)
0.0 0.4 GO:0071985 multivesicular body sorting pathway(GO:0071985)
0.0 0.1 GO:1904798 positive regulation of core promoter binding(GO:1904798)
0.0 0.1 GO:1901355 cellular response to rapamycin(GO:0072752) response to rapamycin(GO:1901355)
0.0 0.1 GO:0043335 protein unfolding(GO:0043335)
0.0 0.4 GO:0036120 cellular response to platelet-derived growth factor stimulus(GO:0036120)
0.0 0.2 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
0.0 0.5 GO:0035855 megakaryocyte development(GO:0035855)
0.0 0.2 GO:1900119 positive regulation of execution phase of apoptosis(GO:1900119)
0.0 0.2 GO:1901409 positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.0 0.1 GO:0042982 amyloid precursor protein metabolic process(GO:0042982)
0.0 0.3 GO:0045898 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.0 0.2 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0 0.1 GO:0040032 post-embryonic body morphogenesis(GO:0040032)
0.0 0.0 GO:0031587 positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0031587)
0.0 0.2 GO:0007252 I-kappaB phosphorylation(GO:0007252)
0.0 1.1 GO:0009301 snRNA transcription(GO:0009301) snRNA transcription from RNA polymerase II promoter(GO:0042795)
0.0 0.1 GO:0000733 DNA strand renaturation(GO:0000733)
0.0 0.2 GO:0070986 left/right axis specification(GO:0070986)
0.0 0.6 GO:0045071 negative regulation of viral genome replication(GO:0045071)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 3.1 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.3 1.0 GO:0097232 lamellar body membrane(GO:0097232) alveolar lamellar body membrane(GO:0097233)
0.1 1.5 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.1 0.4 GO:0030936 collagen type XIII trimer(GO:0005600) transmembrane collagen trimer(GO:0030936)
0.1 6.1 GO:0009925 basal plasma membrane(GO:0009925)
0.1 0.5 GO:0044530 supraspliceosomal complex(GO:0044530)
0.1 6.1 GO:0015030 Cajal body(GO:0015030)
0.1 2.0 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 1.0 GO:0045277 respiratory chain complex IV(GO:0045277)
0.0 0.7 GO:0060077 inhibitory synapse(GO:0060077)
0.0 0.4 GO:0035749 myelin sheath adaxonal region(GO:0035749)
0.0 0.4 GO:0036057 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 0.3 GO:0042788 polysomal ribosome(GO:0042788)
0.0 0.8 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 7.4 GO:0031902 late endosome membrane(GO:0031902)
0.0 2.5 GO:0005643 nuclear pore(GO:0005643)
0.0 5.7 GO:0032587 ruffle membrane(GO:0032587)
0.0 13.5 GO:0031965 nuclear membrane(GO:0031965)
0.0 0.2 GO:0071664 beta-catenin-TCF7L2 complex(GO:0070369) catenin-TCF7L2 complex(GO:0071664)
0.0 0.4 GO:0000974 Prp19 complex(GO:0000974)
0.0 0.4 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 1.9 GO:0035577 azurophil granule membrane(GO:0035577)
0.0 0.2 GO:0061574 ASAP complex(GO:0061574)
0.0 1.3 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 1.2 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 0.1 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
0.0 0.7 GO:0005921 gap junction(GO:0005921)
0.0 0.0 GO:0005674 transcription factor TFIIF complex(GO:0005674)
0.0 0.1 GO:0061617 MICOS complex(GO:0061617)
0.0 0.1 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.0 1.4 GO:0005811 lipid particle(GO:0005811)
0.0 0.1 GO:0031415 NatA complex(GO:0031415)
0.0 0.2 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 0.9 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 0.1 GO:0000408 EKC/KEOPS complex(GO:0000408)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.5 GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
0.5 2.0 GO:0048030 disaccharide binding(GO:0048030)
0.4 1.7 GO:0009041 uridylate kinase activity(GO:0009041)
0.3 1.0 GO:0004145 diamine N-acetyltransferase activity(GO:0004145) polyamine binding(GO:0019808)
0.3 3.0 GO:0042296 ISG15 transferase activity(GO:0042296)
0.2 6.7 GO:0070403 NAD+ binding(GO:0070403)
0.2 1.1 GO:0031849 olfactory receptor binding(GO:0031849)
0.2 2.3 GO:0031386 protein tag(GO:0031386)
0.2 1.1 GO:0042015 interleukin-20 binding(GO:0042015)
0.1 0.8 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.1 2.7 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.1 0.3 GO:0003968 RNA-directed RNA polymerase activity(GO:0003968)
0.1 0.4 GO:0004113 2',3'-cyclic-nucleotide 3'-phosphodiesterase activity(GO:0004113)
0.1 2.7 GO:0032183 SUMO binding(GO:0032183)
0.1 0.3 GO:0004823 leucine-tRNA ligase activity(GO:0004823)
0.1 0.5 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.1 0.3 GO:0004641 phosphoribosylamine-glycine ligase activity(GO:0004637) phosphoribosylformylglycinamidine cyclo-ligase activity(GO:0004641) phosphoribosylglycinamide formyltransferase activity(GO:0004644)
0.1 0.2 GO:0072591 citrate-L-glutamate ligase activity(GO:0072591)
0.1 0.3 GO:0035939 microsatellite binding(GO:0035939)
0.1 1.5 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.1 8.4 GO:0003727 single-stranded RNA binding(GO:0003727)
0.1 7.4 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 0.3 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.0 0.4 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
0.0 1.3 GO:0005521 lamin binding(GO:0005521)
0.0 0.3 GO:0000405 bubble DNA binding(GO:0000405)
0.0 5.4 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.0 17.4 GO:0008017 microtubule binding(GO:0008017)
0.0 0.9 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.0 0.2 GO:0005503 all-trans retinal binding(GO:0005503)
0.0 0.2 GO:0000386 second spliceosomal transesterification activity(GO:0000386)
0.0 1.0 GO:0015002 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.2 GO:0098519 nucleotide phosphatase activity, acting on free nucleotides(GO:0098519)
0.0 0.8 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.5 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0 6.0 GO:0030674 protein binding, bridging(GO:0030674)
0.0 1.4 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
0.0 0.1 GO:0004877 complement component C4b receptor activity(GO:0001861) complement component C3b receptor activity(GO:0004877)
0.0 1.1 GO:0001972 retinoic acid binding(GO:0001972)
0.0 1.3 GO:0050136 NADH dehydrogenase activity(GO:0003954) NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.2 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.0 0.2 GO:0004111 creatine kinase activity(GO:0004111)
0.0 0.0 GO:0001054 RNA polymerase I activity(GO:0001054)
0.0 0.1 GO:0033754 indoleamine 2,3-dioxygenase activity(GO:0033754)
0.0 0.6 GO:0031078 NAD-dependent histone deacetylase activity(GO:0017136) histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041) NAD-dependent protein deacetylase activity(GO:0034979)
0.0 0.1 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
0.0 0.5 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.0 2.6 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 1.8 GO:0097110 scaffold protein binding(GO:0097110)
0.0 0.1 GO:0070984 SET domain binding(GO:0070984)
0.0 0.2 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.0 0.1 GO:0015485 cholesterol binding(GO:0015485) sterol binding(GO:0032934)
0.0 0.1 GO:0019763 immunoglobulin receptor activity(GO:0019763)
0.0 0.1 GO:0097617 annealing helicase activity(GO:0036310) annealing activity(GO:0097617)
0.0 0.1 GO:0050815 phosphoserine binding(GO:0050815)
0.0 0.3 GO:0003680 AT DNA binding(GO:0003680)
0.0 1.6 GO:0005198 structural molecule activity(GO:0005198)
0.0 1.1 GO:0004004 ATP-dependent RNA helicase activity(GO:0004004) RNA-dependent ATPase activity(GO:0008186)
0.0 0.2 GO:0032395 MHC class II receptor activity(GO:0032395)
0.0 0.6 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.4 GO:0001784 phosphotyrosine binding(GO:0001784)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.9 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.1 4.6 PID MYC PATHWAY C-MYC pathway
0.0 4.1 PID TCPTP PATHWAY Signaling events mediated by TCPTP
0.0 0.8 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 3.8 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 0.9 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 0.9 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.0 0.7 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 1.4 SIG PIP3 SIGNALING IN CARDIAC MYOCTES Genes related to PIP3 signaling in cardiac myocytes
0.0 1.1 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 2.8 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 12.6 REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.4 38.9 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.1 3.1 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.1 2.9 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.1 0.7 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0 3.3 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.0 2.1 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 0.9 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.7 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 0.5 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.4 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.0 1.5 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 0.4 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.0 0.3 REACTOME FORMATION OF TRANSCRIPTION COUPLED NER TC NER REPAIR COMPLEX Genes involved in Formation of transcription-coupled NER (TC-NER) repair complex
0.0 0.3 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.4 REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)