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SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for IRF7

Z-value: 0.53

Motif logo

Transcription factors associated with IRF7

Gene Symbol Gene ID Gene Info
ENSG00000185507.15 interferon regulatory factor 7

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
IRF7hg19_v2_chr11_-_615570_6157280.351.3e-01Click!

Activity profile of IRF7 motif

Sorted Z-values of IRF7 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr10_+_91152303 1.58 ENST00000371804.3
interferon-induced protein with tetratricopeptide repeats 1
chr1_+_948803 0.93 ENST00000379389.4
ISG15 ubiquitin-like modifier
chr10_+_91061712 0.74 ENST00000371826.3
interferon-induced protein with tetratricopeptide repeats 2
chr8_-_145060593 0.60 ENST00000313059.5
ENST00000524918.1
ENST00000313028.7
ENST00000525773.1
poly (ADP-ribose) polymerase family, member 10
chr10_+_91092241 0.54 ENST00000371811.4
interferon-induced protein with tetratricopeptide repeats 3
chr2_-_231084659 0.52 ENST00000258381.6
ENST00000358662.4
ENST00000455674.1
ENST00000392048.3
SP110 nuclear body protein
chr19_+_39759154 0.52 ENST00000331982.5
interferon, lambda 2
chr11_-_615942 0.43 ENST00000397562.3
ENST00000330243.5
ENST00000397570.1
ENST00000397574.2
interferon regulatory factor 7
chr10_+_91087651 0.39 ENST00000371818.4
interferon-induced protein with tetratricopeptide repeats 3
chr1_+_79115503 0.38 ENST00000370747.4
ENST00000438486.1
ENST00000545124.1
interferon-induced protein 44
chr11_-_615570 0.38 ENST00000525445.1
ENST00000348655.6
ENST00000397566.1
interferon regulatory factor 7
chr4_-_169401628 0.37 ENST00000514748.1
ENST00000512371.1
ENST00000260184.7
ENST00000505890.1
ENST00000511577.1
DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like
chr19_+_39786962 0.36 ENST00000333625.2
interferon, lambda 1
chr14_+_94577074 0.32 ENST00000444961.1
ENST00000448882.1
ENST00000557098.1
ENST00000554800.1
ENST00000556544.1
ENST00000298902.5
ENST00000555819.1
ENST00000557634.1
ENST00000555744.1
interferon, alpha-inducible protein 27
chr12_+_113416265 0.30 ENST00000449768.2
2'-5'-oligoadenylate synthetase 2, 69/71kDa
chr19_-_39735646 0.29 ENST00000413851.2
interferon, lambda 3
chr2_-_231084820 0.28 ENST00000258382.5
ENST00000338556.3
SP110 nuclear body protein
chr12_+_113416191 0.27 ENST00000342315.4
ENST00000392583.2
2'-5'-oligoadenylate synthetase 2, 69/71kDa
chr11_-_64764435 0.26 ENST00000534177.1
ENST00000301887.4
basic leucine zipper transcription factor, ATF-like 2
chr12_+_113344582 0.25 ENST00000202917.5
ENST00000445409.2
ENST00000452357.2
2'-5'-oligoadenylate synthetase 1, 40/46kDa
chr1_-_150693318 0.24 ENST00000442853.1
ENST00000368995.4
ENST00000368993.2
ENST00000361824.2
ENST00000322343.7
HORMA domain containing 1
chr9_-_32526299 0.24 ENST00000379882.1
ENST00000379883.2
DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
chr9_-_32526184 0.24 ENST00000545044.1
ENST00000379868.1
DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
chr12_+_113344755 0.23 ENST00000550883.1
2'-5'-oligoadenylate synthetase 1, 40/46kDa
chr2_-_231084617 0.22 ENST00000409815.2
SP110 nuclear body protein
chr2_-_7005785 0.21 ENST00000256722.5
ENST00000404168.1
ENST00000458098.1
cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial
chr2_-_188419078 0.21 ENST00000437725.1
ENST00000409676.1
ENST00000339091.4
ENST00000420747.1
tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
chr19_-_17516449 0.21 ENST00000252593.6
bone marrow stromal cell antigen 2
chr1_+_158979680 0.21 ENST00000368131.4
ENST00000340979.6
interferon, gamma-inducible protein 16
chr4_+_103790462 0.19 ENST00000503643.1
CDGSH iron sulfur domain 2
chr1_+_158979792 0.19 ENST00000359709.3
ENST00000430894.2
interferon, gamma-inducible protein 16
chr2_-_191878162 0.19 ENST00000540176.1
signal transducer and activator of transcription 1, 91kDa
chr2_+_7017796 0.18 ENST00000382040.3
radical S-adenosyl methionine domain containing 2
chr2_-_191878874 0.18 ENST00000392322.3
ENST00000392323.2
ENST00000424722.1
ENST00000361099.3
signal transducer and activator of transcription 1, 91kDa
chr2_-_191878681 0.18 ENST00000409465.1
signal transducer and activator of transcription 1, 91kDa
chr11_-_321050 0.18 ENST00000399808.4
interferon induced transmembrane protein 3
chr4_-_169239921 0.18 ENST00000514995.1
ENST00000393743.3
DEAD (Asp-Glu-Ala-Asp) box polypeptide 60
chr1_-_150693305 0.18 ENST00000368987.1
HORMA domain containing 1
chr10_+_91174486 0.18 ENST00000416601.1
interferon-induced protein with tetratricopeptide repeats 5
chr1_+_158979686 0.17 ENST00000368132.3
ENST00000295809.7
interferon, gamma-inducible protein 16
chr2_-_163175133 0.17 ENST00000421365.2
ENST00000263642.2
interferon induced with helicase C domain 1
chr2_-_188419200 0.17 ENST00000233156.3
ENST00000426055.1
ENST00000453013.1
ENST00000417013.1
tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
chr17_+_6659153 0.17 ENST00000441631.1
ENST00000438512.1
ENST00000346752.4
ENST00000361842.3
XIAP associated factor 1
chr2_-_55237484 0.17 ENST00000394609.2
reticulon 4
chr9_-_119162885 0.16 ENST00000445861.2
PAPPA antisense RNA 1
chr7_-_92777606 0.16 ENST00000437805.1
ENST00000446959.1
ENST00000439952.1
ENST00000414791.1
ENST00000446033.1
ENST00000411955.1
ENST00000318238.4
sterile alpha motif domain containing 9-like
chr3_-_49851313 0.16 ENST00000333486.3
ubiquitin-like modifier activating enzyme 7
chr22_+_36649056 0.15 ENST00000397278.3
ENST00000422706.1
ENST00000426053.1
ENST00000319136.4
apolipoprotein L, 1
chr22_+_18632666 0.15 ENST00000215794.7
ubiquitin specific peptidase 18
chr3_-_28390120 0.15 ENST00000334100.6
5-azacytidine induced 2
chr12_-_10007448 0.15 ENST00000538152.1
C-type lectin domain family 2, member B
chr10_+_91174314 0.15 ENST00000371795.4
interferon-induced protein with tetratricopeptide repeats 5
chr11_+_17298522 0.15 ENST00000529313.1
nucleobindin 2
chr3_-_122283100 0.14 ENST00000492382.1
ENST00000462315.1
poly (ADP-ribose) polymerase family, member 9
chr20_+_10199468 0.14 ENST00000254976.2
ENST00000304886.2
synaptosomal-associated protein, 25kDa
chr1_-_114430169 0.14 ENST00000393316.3
BCL2-like 15
chr6_+_32811861 0.14 ENST00000453426.1
TAP1 and PSMB8 antisense RNA 1
chr4_+_41614909 0.14 ENST00000509454.1
ENST00000396595.3
ENST00000381753.4
LIM and calponin homology domains 1
chr3_+_122399444 0.14 ENST00000474629.2
poly (ADP-ribose) polymerase family, member 14
chr6_+_32821924 0.14 ENST00000374859.2
ENST00000453265.2
proteasome (prosome, macropain) subunit, beta type, 9
chr5_+_133707252 0.13 ENST00000506787.1
ENST00000507277.1
ubiquitin-conjugating enzyme E2B
chr4_-_14889791 0.13 ENST00000509654.1
ENST00000515031.1
ENST00000505089.2
long intergenic non-protein coding RNA 504
chr3_-_122283079 0.13 ENST00000471785.1
ENST00000466126.1
poly (ADP-ribose) polymerase family, member 9
chr14_-_35182994 0.13 ENST00000341223.3
cofilin 2 (muscle)
chr17_-_57229155 0.13 ENST00000584089.1
spindle and kinetochore associated complex subunit 2
chr11_+_5646213 0.13 ENST00000429814.2
tripartite motif containing 34
chr16_+_57023406 0.13 ENST00000262510.6
ENST00000308149.7
ENST00000436936.1
NLR family, CARD domain containing 5
chr5_+_133706865 0.13 ENST00000265339.2
ubiquitin-conjugating enzyme E2B
chr15_+_35270552 0.13 ENST00000391457.2
HCG37415; PRO1914; Uncharacterized protein
chr19_+_10196781 0.12 ENST00000253110.11
chromosome 19 open reading frame 66
chr2_-_231090344 0.12 ENST00000540870.1
ENST00000416610.1
SP110 nuclear body protein
chr7_-_134143841 0.12 ENST00000285930.4
aldo-keto reductase family 1, member B1 (aldose reductase)
chr7_-_76955563 0.12 ENST00000441833.2
gamma-secretase activating protein
chr12_-_10022735 0.12 ENST00000228438.2
C-type lectin domain family 2, member B
chr1_-_111506562 0.12 ENST00000485275.2
ENST00000369763.4
ligand dependent nuclear receptor interacting factor 1
chr1_+_112016414 0.12 ENST00000343534.5
ENST00000369718.3
chromosome 1 open reading frame 162
chr3_-_28390298 0.12 ENST00000457172.1
5-azacytidine induced 2
chrX_+_51486481 0.12 ENST00000340438.4
G1 to S phase transition 2
chr17_-_40264692 0.12 ENST00000591220.1
ENST00000251642.3
DEXH (Asp-Glu-X-His) box polypeptide 58
chr9_-_21077939 0.12 ENST00000380232.2
interferon, beta 1, fibroblast
chr15_+_45003675 0.12 ENST00000558401.1
ENST00000559916.1
ENST00000544417.1
beta-2-microglobulin
chr2_-_37384175 0.12 ENST00000411537.2
ENST00000233057.4
ENST00000395127.2
ENST00000390013.3
eukaryotic translation initiation factor 2-alpha kinase 2
chr5_+_34915444 0.12 ENST00000336767.5
BRX1, biogenesis of ribosomes, homolog (S. cerevisiae)
chr15_+_63354769 0.12 ENST00000558910.1
tropomyosin 1 (alpha)
chr6_+_122931366 0.12 ENST00000368452.2
ENST00000368448.1
ENST00000392490.1
protein kinase (cAMP-dependent, catalytic) inhibitor beta
chr13_+_50070077 0.12 ENST00000378319.3
ENST00000426879.1
PHD finger protein 11
chr16_-_11350036 0.12 ENST00000332029.2
suppressor of cytokine signaling 1
chr19_+_49977466 0.12 ENST00000596435.1
ENST00000344019.3
ENST00000597551.1
ENST00000204637.2
ENST00000600429.1
fms-related tyrosine kinase 3 ligand
chr14_+_73563735 0.12 ENST00000532192.1
RNA binding motif protein 25
chr1_+_79086088 0.12 ENST00000370751.5
ENST00000342282.3
interferon-induced protein 44-like
chr1_-_150738261 0.12 ENST00000448301.2
ENST00000368985.3
cathepsin S
chr12_-_49463620 0.11 ENST00000550675.1
Ras homolog enriched in brain like 1
chr16_-_67597789 0.11 ENST00000605277.1
CTD-2012K14.6
chr9_+_100174344 0.11 ENST00000422139.2
tudor domain containing 7
chr12_-_8693539 0.11 ENST00000299663.3
C-type lectin domain family 4, member E
chr15_+_78832747 0.11 ENST00000560217.1
ENST00000044462.7
ENST00000559082.1
ENST00000559948.1
ENST00000413382.2
ENST00000559146.1
ENST00000558281.1
proteasome (prosome, macropain) subunit, alpha type, 4
chr3_+_159706537 0.11 ENST00000305579.2
ENST00000480787.1
ENST00000466512.1
interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35)
chr11_-_47736896 0.11 ENST00000525123.1
ENST00000528244.1
ENST00000532595.1
ENST00000529154.1
ENST00000530969.1
ATP/GTP binding protein-like 2
chr1_-_89531041 0.11 ENST00000370473.4
guanylate binding protein 1, interferon-inducible
chr13_-_33112823 0.11 ENST00000504114.1
NEDD4 binding protein 2-like 2
chr14_-_54420133 0.11 ENST00000559501.1
ENST00000558984.1
bone morphogenetic protein 4
chr11_+_17298543 0.11 ENST00000533926.1
nucleobindin 2
chrX_-_119693745 0.11 ENST00000371323.2
cullin 4B
chr17_-_76975925 0.10 ENST00000591274.1
ENST00000589906.1
ENST00000591778.1
ENST00000589775.2
ENST00000585407.1
ENST00000262776.3
lectin, galactoside-binding, soluble, 3 binding protein
chr22_-_29107919 0.10 ENST00000434810.1
ENST00000456369.1
checkpoint kinase 2
chr12_+_113344811 0.10 ENST00000551241.1
ENST00000553185.1
ENST00000550689.1
2'-5'-oligoadenylate synthetase 1, 40/46kDa
chr20_+_5892037 0.10 ENST00000378961.4
chromogranin B (secretogranin 1)
chr3_-_114035026 0.10 ENST00000570269.1
RP11-553L6.5
chr17_-_62499334 0.10 ENST00000579996.1
DEAD (Asp-Glu-Ala-Asp) box helicase 5
chr1_+_25664408 0.10 ENST00000374358.4
transmembrane protein 50A
chr8_+_90914073 0.10 ENST00000297438.2
oxidative stress induced growth inhibitor family member 2
chrX_-_34675391 0.10 ENST00000275954.3
transmembrane protein 47
chr22_+_36649170 0.10 ENST00000438034.1
ENST00000427990.1
ENST00000347595.7
ENST00000397279.4
ENST00000433768.1
ENST00000440669.2
apolipoprotein L, 1
chr15_-_80263506 0.10 ENST00000335661.6
BCL2-related protein A1
chr22_-_22641542 0.10 ENST00000606654.1
LL22NC03-2H8.5
chr11_-_104905840 0.10 ENST00000526568.1
ENST00000393136.4
ENST00000531166.1
ENST00000534497.1
ENST00000527979.1
ENST00000446369.1
ENST00000353247.5
ENST00000528974.1
ENST00000533400.1
ENST00000525825.1
ENST00000436863.3
caspase 1, apoptosis-related cysteine peptidase
chr2_-_152146385 0.10 ENST00000414946.1
ENST00000243346.5
N-myc (and STAT) interactor
chrX_+_78003204 0.10 ENST00000435339.3
ENST00000514744.1
lysophosphatidic acid receptor 4
chr11_-_57335280 0.10 ENST00000287156.4
ubiquitin-conjugating enzyme E2L 6
chr6_+_32811885 0.10 ENST00000458296.1
ENST00000413039.1
ENST00000429600.1
ENST00000412095.1
ENST00000415067.1
ENST00000395330.1
TAP1 and PSMB8 antisense RNA 1
proteasome (prosome, macropain) subunit, beta type, 9
chr11_+_46402482 0.10 ENST00000441869.1
midkine (neurite growth-promoting factor 2)
chr9_+_100174232 0.09 ENST00000355295.4
tudor domain containing 7
chr22_-_22901636 0.09 ENST00000406503.1
ENST00000439106.1
ENST00000402697.1
ENST00000543184.1
ENST00000398743.2
preferentially expressed antigen in melanoma
chr17_+_41158742 0.09 ENST00000415816.2
ENST00000438323.2
interferon-induced protein 35
chr17_-_38978847 0.09 ENST00000269576.5
keratin 10
chr12_-_8693469 0.09 ENST00000545274.1
ENST00000446457.2
C-type lectin domain family 4, member E
chr2_-_152118352 0.09 ENST00000331426.5
RNA binding motif protein 43
chr22_+_36044411 0.09 ENST00000409652.4
apolipoprotein L, 6
chr5_+_38846101 0.09 ENST00000274276.3
oncostatin M receptor
chr4_-_36245561 0.09 ENST00000506189.1
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr10_-_5446786 0.09 ENST00000479328.1
ENST00000380419.3
tubulin, alpha-like 3
chrX_+_135278908 0.09 ENST00000539015.1
ENST00000370683.1
four and a half LIM domains 1
chr2_+_169658928 0.09 ENST00000317647.7
ENST00000445023.2
nitric oxide synthase trafficking
chr5_-_38845812 0.09 ENST00000513480.1
ENST00000512519.1
CTD-2127H9.1
chr22_-_22901477 0.09 ENST00000420709.1
ENST00000398741.1
ENST00000405655.3
preferentially expressed antigen in melanoma
chr12_+_19358192 0.09 ENST00000538305.1
pleckstrin homology domain containing, family A member 5
chr9_-_100881466 0.08 ENST00000341469.2
ENST00000342043.3
ENST00000375098.3
tripartite motif containing 14
chr13_+_20532848 0.08 ENST00000382874.2
zinc finger, MYM-type 2
chr1_+_186265399 0.08 ENST00000367486.3
ENST00000367484.3
ENST00000533951.1
ENST00000367482.4
ENST00000367483.4
ENST00000367485.4
ENST00000445192.2
proteoglycan 4
chr22_-_36635684 0.08 ENST00000358502.5
apolipoprotein L, 2
chrX_-_71525742 0.08 ENST00000450875.1
ENST00000417400.1
ENST00000431381.1
ENST00000445983.1
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1
chr9_-_75567962 0.08 ENST00000297785.3
ENST00000376939.1
aldehyde dehydrogenase 1 family, member A1
chr5_+_180682720 0.08 ENST00000599439.1
CDNA: FLJ23158 fis, clone LNG09623; Uncharacterized protein
chr21_+_35107346 0.08 ENST00000456489.1
intersectin 1 (SH3 domain protein)
chr1_+_63833261 0.08 ENST00000371108.4
ALG6, alpha-1,3-glucosyltransferase
chr14_-_35183755 0.08 ENST00000555765.1
cofilin 2 (muscle)
chr11_-_112034780 0.08 ENST00000524595.1
interleukin 18 (interferon-gamma-inducing factor)
chr14_-_35099377 0.08 ENST00000362031.4
sorting nexin 6
chr3_-_28390415 0.08 ENST00000414162.1
ENST00000420543.2
5-azacytidine induced 2
chr17_-_46623441 0.08 ENST00000330070.4
homeobox B2
chr12_+_11802753 0.08 ENST00000396373.4
ets variant 6
chr14_-_23288930 0.08 ENST00000554517.1
ENST00000285850.7
ENST00000397529.2
ENST00000555702.1
solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
chr2_-_55277692 0.08 ENST00000394611.2
reticulon 4
chr9_-_20622478 0.08 ENST00000355930.6
ENST00000380338.4
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
chr1_+_186798073 0.08 ENST00000367466.3
ENST00000442353.2
phospholipase A2, group IVA (cytosolic, calcium-dependent)
chr7_-_93519471 0.08 ENST00000451238.1
tissue factor pathway inhibitor 2
chr3_+_122283064 0.08 ENST00000296161.4
deltex 3-like (Drosophila)
chr2_+_99771418 0.08 ENST00000393473.2
ENST00000393477.3
ENST00000393474.3
ENST00000340066.1
ENST00000393471.2
ENST00000449211.1
ENST00000434566.1
ENST00000410042.1
lipoyltransferase 1
39S ribosomal protein L30, mitochondrial
chr11_-_5537920 0.08 ENST00000380184.1
ubiquilin-like
chr11_-_57334732 0.08 ENST00000526659.1
ENST00000527022.1
ubiquitin-conjugating enzyme E2L 6
chr7_-_138794394 0.08 ENST00000242351.5
ENST00000471652.1
zinc finger CCCH-type, antiviral 1
chr12_+_113376157 0.08 ENST00000228928.7
2'-5'-oligoadenylate synthetase 3, 100kDa
chr12_+_43086018 0.08 ENST00000550177.1
RP11-25I15.3
chr1_+_104068562 0.08 ENST00000423855.2
RNA-binding region (RNP1, RRM) containing 3
chrX_+_102631248 0.08 ENST00000361298.4
ENST00000372645.3
ENST00000372635.1
nerve growth factor receptor (TNFRSF16) associated protein 1
chr2_+_172950227 0.08 ENST00000341900.6
distal-less homeobox 1
chr3_+_178865887 0.07 ENST00000477735.1
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
chr8_+_97597148 0.07 ENST00000521590.1
syndecan 2
chr3_-_28390581 0.07 ENST00000479665.1
5-azacytidine induced 2
chr12_-_10282742 0.07 ENST00000298523.5
ENST00000396484.2
ENST00000310002.4
C-type lectin domain family 7, member A
chr1_-_114429997 0.07 ENST00000471267.1
ENST00000393320.3
BCL2-like 15
chr11_+_63304273 0.07 ENST00000439013.2
ENST00000255688.3
retinoic acid receptor responder (tazarotene induced) 3
chr21_+_35553045 0.07 ENST00000416145.1
ENST00000430922.1
ENST00000419881.2
long intergenic non-protein coding RNA 310
chr18_+_61575200 0.07 ENST00000238508.3
serpin peptidase inhibitor, clade B (ovalbumin), member 10
chrX_+_591524 0.07 ENST00000554971.1
ENST00000381575.1
short stature homeobox
chr8_-_17752996 0.07 ENST00000381841.2
ENST00000427924.1
fibrinogen-like 1
chr18_+_3252265 0.07 ENST00000580887.1
ENST00000536605.1
myosin, light chain 12A, regulatory, non-sarcomeric
chr6_+_87865262 0.07 ENST00000369577.3
ENST00000518845.1
ENST00000339907.4
ENST00000496806.2
zinc finger protein 292
chrX_-_71526999 0.07 ENST00000453707.2
ENST00000373619.3
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1
chr19_+_10196981 0.07 ENST00000591813.1
chromosome 19 open reading frame 66
chr1_+_113217309 0.07 ENST00000544796.1
ENST00000369644.1
Mov10, Moloney leukemia virus 10, homolog (mouse)
chr8_-_82608409 0.07 ENST00000518568.1
solute carrier family 10, member 5
chr22_-_36635563 0.07 ENST00000451256.2
apolipoprotein L, 2
chr22_-_36556821 0.07 ENST00000531095.1
ENST00000397293.2
ENST00000349314.2
apolipoprotein L, 3
chr14_+_24605389 0.07 ENST00000382708.3
ENST00000561435.1
proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)
chr11_-_119249805 0.07 ENST00000527843.1
ubiquitin specific peptidase 2
chr6_+_134273321 0.07 ENST00000457715.1
TBP-like 1
chr14_+_58711539 0.07 ENST00000216455.4
ENST00000412908.2
ENST00000557508.1
proteasome (prosome, macropain) subunit, alpha type, 3
chr12_+_19358228 0.06 ENST00000424268.1
ENST00000543806.1
pleckstrin homology domain containing, family A member 5
chr7_-_102985035 0.06 ENST00000426036.2
ENST00000249270.7
ENST00000454277.1
ENST00000412522.1
DnaJ (Hsp40) homolog, subfamily C, member 2
chr4_-_155511887 0.06 ENST00000302053.3
ENST00000403106.3
fibrinogen alpha chain
chr17_-_65362678 0.06 ENST00000357146.4
ENST00000356126.3
proteasome (prosome, macropain) 26S subunit, non-ATPase, 12
chr8_+_17434689 0.06 ENST00000398074.3
platelet-derived growth factor receptor-like
chr4_-_76944621 0.06 ENST00000306602.1
chemokine (C-X-C motif) ligand 10
chr3_+_188817891 0.06 ENST00000412373.1
tumor protein p63 regulated 1
chr1_+_43613612 0.06 ENST00000335282.4
family with sequence similarity 183, member A
chr10_+_94608245 0.06 ENST00000443748.2
ENST00000260762.6
exocyst complex component 6
chr1_+_92632542 0.06 ENST00000409154.4
ENST00000370378.4
KIAA1107
chr4_+_78804393 0.06 ENST00000502384.1
mitochondrial ribosomal protein L1
chr17_-_40264321 0.06 ENST00000430773.1
ENST00000413196.2
DEXH (Asp-Glu-X-His) box polypeptide 58

Network of associatons between targets according to the STRING database.

First level regulatory network of IRF7

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.6 GO:0051097 negative regulation of helicase activity(GO:0051097)
0.2 0.7 GO:0034344 type III interferon production(GO:0034343) regulation of type III interferon production(GO:0034344)
0.2 0.8 GO:2000110 negative regulation of macrophage apoptotic process(GO:2000110)
0.1 0.4 GO:0060629 regulation of homologous chromosome segregation(GO:0060629)
0.1 0.6 GO:0072308 negative regulation by virus of viral protein levels in host cell(GO:0046725) negative regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072308)
0.1 1.7 GO:0035457 cellular response to interferon-alpha(GO:0035457)
0.1 0.6 GO:0010847 regulation of chromatin assembly(GO:0010847) protein auto-ADP-ribosylation(GO:0070213)
0.1 1.3 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.1 0.3 GO:0010845 positive regulation of reciprocal meiotic recombination(GO:0010845)
0.1 0.2 GO:1901253 negative regulation of intracellular transport of viral material(GO:1901253)
0.1 0.4 GO:1900245 positive regulation of MDA-5 signaling pathway(GO:1900245)
0.1 0.5 GO:0044565 dendritic cell proliferation(GO:0044565)
0.1 0.6 GO:0018377 protein myristoylation(GO:0018377)
0.1 0.4 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
0.1 0.2 GO:0009138 pyrimidine nucleoside diphosphate metabolic process(GO:0009138)
0.0 0.6 GO:0045343 MHC class I biosynthetic process(GO:0045341) regulation of MHC class I biosynthetic process(GO:0045343)
0.0 0.4 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
0.0 0.1 GO:0006059 hexitol metabolic process(GO:0006059)
0.0 0.1 GO:0002184 cytoplasmic translational termination(GO:0002184)
0.0 0.1 GO:0006663 platelet activating factor biosynthetic process(GO:0006663)
0.0 0.1 GO:1990926 short-term synaptic potentiation(GO:1990926)
0.0 0.1 GO:0072428 signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926)
0.0 0.1 GO:0002428 antigen processing and presentation of peptide antigen via MHC class Ib(GO:0002428)
0.0 0.2 GO:0034165 positive regulation of toll-like receptor 9 signaling pathway(GO:0034165)
0.0 0.1 GO:0046967 cytosol to ER transport(GO:0046967)
0.0 0.2 GO:0003340 negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis(GO:0003340)
0.0 0.1 GO:0021569 rhombomere 3 development(GO:0021569)
0.0 0.1 GO:0031448 regulation of fast-twitch skeletal muscle fiber contraction(GO:0031446) positive regulation of fast-twitch skeletal muscle fiber contraction(GO:0031448)
0.0 0.1 GO:0051083 'de novo' cotranslational protein folding(GO:0051083)
0.0 0.1 GO:1901254 modulation by host of viral RNA genome replication(GO:0044830) positive regulation of intracellular transport of viral material(GO:1901254)
0.0 0.1 GO:0021882 regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment(GO:0021882) cerebral cortex GABAergic interneuron fate commitment(GO:0021893) positive regulation of neural retina development(GO:0061075) positive regulation of retina development in camera-type eye(GO:1902868) positive regulation of amacrine cell differentiation(GO:1902871)
0.0 0.1 GO:0030885 regulation of myeloid dendritic cell activation(GO:0030885)
0.0 0.2 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787)
0.0 0.1 GO:0055020 apoptotic process involved in endocardial cushion morphogenesis(GO:0003277) intermediate mesoderm morphogenesis(GO:0048390) intermediate mesoderm formation(GO:0048391) intermediate mesodermal cell differentiation(GO:0048392) regulation of cardiac muscle fiber development(GO:0055018) positive regulation of cardiac muscle fiber development(GO:0055020) bud dilation involved in lung branching(GO:0060503) BMP signaling pathway involved in ureter morphogenesis(GO:0061149) renal system segmentation(GO:0061150) BMP signaling pathway involved in renal system segmentation(GO:0061151) pulmonary artery endothelial tube morphogenesis(GO:0061155) regulation of transcription from RNA polymerase II promoter involved in mesonephros development(GO:0061216) BMP signaling pathway involved in nephric duct formation(GO:0071893) negative regulation of branch elongation involved in ureteric bud branching(GO:0072096) negative regulation of branch elongation involved in ureteric bud branching by BMP signaling pathway(GO:0072097) anterior/posterior pattern specification involved in ureteric bud development(GO:0072099) specification of ureteric bud anterior/posterior symmetry(GO:0072100) specification of ureteric bud anterior/posterior symmetry by BMP signaling pathway(GO:0072101) ureter epithelial cell differentiation(GO:0072192) negative regulation of mesenchymal cell proliferation involved in ureter development(GO:0072200) regulation of cell proliferation involved in outflow tract morphogenesis(GO:1901963) positive regulation of cell proliferation involved in outflow tract morphogenesis(GO:1901964) cardiac jelly development(GO:1905072) regulation of metanephric S-shaped body morphogenesis(GO:2000004) negative regulation of metanephric S-shaped body morphogenesis(GO:2000005) regulation of metanephric comma-shaped body morphogenesis(GO:2000006) negative regulation of metanephric comma-shaped body morphogenesis(GO:2000007)
0.0 0.1 GO:0045349 interferon-alpha biosynthetic process(GO:0045349) regulation of interferon-alpha biosynthetic process(GO:0045354)
0.0 0.1 GO:0042231 interleukin-13 biosynthetic process(GO:0042231)
0.0 2.0 GO:0045071 negative regulation of viral genome replication(GO:0045071)
0.0 0.1 GO:0030421 defecation(GO:0030421)
0.0 0.1 GO:0044029 DNA hypomethylation(GO:0044028) hypomethylation of CpG island(GO:0044029)
0.0 0.1 GO:0052148 modulation by virus of host molecular function(GO:0039506) suppression by virus of host molecular function(GO:0039507) suppression by virus of host catalytic activity(GO:0039513) modulation by virus of host catalytic activity(GO:0039516) suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process(GO:0039650) negative regulation by symbiont of host catalytic activity(GO:0052053) negative regulation by symbiont of host molecular function(GO:0052056) modulation by symbiont of host catalytic activity(GO:0052148)
0.0 0.1 GO:1900041 negative regulation of interleukin-2 secretion(GO:1900041)
0.0 0.1 GO:0009212 dTTP biosynthetic process(GO:0006235) pyrimidine deoxyribonucleoside triphosphate biosynthetic process(GO:0009212)
0.0 0.1 GO:1903593 regulation of histamine secretion by mast cell(GO:1903593)
0.0 0.1 GO:0002728 negative regulation of natural killer cell cytokine production(GO:0002728)
0.0 0.0 GO:0060648 mammary gland bud morphogenesis(GO:0060648)
0.0 0.0 GO:1902362 melanocyte apoptotic process(GO:1902362)
0.0 0.2 GO:0035279 mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing(GO:0098795)
0.0 0.1 GO:0050717 positive regulation of interleukin-1 alpha secretion(GO:0050717)
0.0 0.0 GO:0046832 negative regulation of nucleobase-containing compound transport(GO:0032240) negative regulation of RNA export from nucleus(GO:0046832)
0.0 0.4 GO:0042832 defense response to protozoan(GO:0042832)
0.0 0.1 GO:0003065 positive regulation of heart rate by epinephrine(GO:0003065)
0.0 0.1 GO:0099640 axo-dendritic protein transport(GO:0099640)
0.0 0.1 GO:0090086 negative regulation of protein deubiquitination(GO:0090086)
0.0 0.1 GO:1902035 positive regulation of hematopoietic stem cell proliferation(GO:1902035)
0.0 0.1 GO:0035610 protein side chain deglutamylation(GO:0035610)
0.0 0.1 GO:0061624 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
0.0 0.4 GO:0002385 mucosal immune response(GO:0002385)
0.0 0.1 GO:1903588 negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903588)
0.0 0.2 GO:0030043 actin filament fragmentation(GO:0030043)
0.0 0.1 GO:1904073 trophectodermal cell proliferation(GO:0001834) regulation of trophectodermal cell proliferation(GO:1904073) positive regulation of trophectodermal cell proliferation(GO:1904075)
0.0 0.1 GO:0010533 regulation of activation of Janus kinase activity(GO:0010533)
0.0 0.0 GO:1905154 negative regulation of membrane invagination(GO:1905154) calcium ion regulated lysosome exocytosis(GO:1990927)
0.0 0.0 GO:0061074 regulation of neural retina development(GO:0061074)
0.0 0.0 GO:0046103 adenosine catabolic process(GO:0006154) inosine biosynthetic process(GO:0046103)
0.0 0.0 GO:0090071 negative regulation of ribosome biogenesis(GO:0090071)
0.0 0.0 GO:0070634 transepithelial ammonium transport(GO:0070634)
0.0 0.1 GO:0097039 protein linear polyubiquitination(GO:0097039)
0.0 0.1 GO:0038165 oncostatin-M-mediated signaling pathway(GO:0038165)
0.0 0.0 GO:0035262 gonad morphogenesis(GO:0035262)
0.0 0.0 GO:0050720 interleukin-1 beta biosynthetic process(GO:0050720)
0.0 0.0 GO:1900365 positive regulation of mRNA polyadenylation(GO:1900365)
0.0 0.1 GO:0060355 positive regulation of cell adhesion molecule production(GO:0060355)
0.0 0.1 GO:0060437 lung growth(GO:0060437)
0.0 0.0 GO:0048687 modulation by virus of host transcription(GO:0019056) positive regulation of sprouting of injured axon(GO:0048687) positive regulation of axon extension involved in regeneration(GO:0048691) modulation by symbiont of host transcription(GO:0052026)
0.0 0.1 GO:1902728 mineralocorticoid receptor signaling pathway(GO:0031959) positive regulation of skeletal muscle satellite cell proliferation(GO:1902724) positive regulation of growth factor dependent skeletal muscle satellite cell proliferation(GO:1902728)
0.0 0.1 GO:0008218 bioluminescence(GO:0008218)
0.0 0.1 GO:0009257 10-formyltetrahydrofolate biosynthetic process(GO:0009257)
0.0 0.0 GO:0032641 lymphotoxin A production(GO:0032641) lymphotoxin A biosynthetic process(GO:0042109)
0.0 0.0 GO:0045062 extrathymic T cell selection(GO:0045062)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0032002 interleukin-28 receptor complex(GO:0032002)
0.0 0.1 GO:0018444 translation release factor complex(GO:0018444)
0.0 0.2 GO:0008537 proteasome activator complex(GO:0008537)
0.0 0.1 GO:0005900 oncostatin-M receptor complex(GO:0005900)
0.0 0.3 GO:0033503 HULC complex(GO:0033503)
0.0 0.2 GO:0097179 protease inhibitor complex(GO:0097179)
0.0 0.1 GO:1902737 dendritic filopodium(GO:1902737)
0.0 0.1 GO:0097454 Schwann cell microvillus(GO:0097454)
0.0 0.2 GO:1990111 spermatoproteasome complex(GO:1990111)
0.0 0.1 GO:0031905 early endosome lumen(GO:0031905)
0.0 0.1 GO:0031233 intrinsic component of external side of plasma membrane(GO:0031233)
0.0 0.3 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 0.1 GO:0071797 LUBAC complex(GO:0071797)
0.0 0.1 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
0.0 0.1 GO:0097422 tubular endosome(GO:0097422)
0.0 0.1 GO:0031213 RSF complex(GO:0031213)
0.0 0.1 GO:0036021 endolysosome lumen(GO:0036021)
0.0 0.1 GO:0005600 collagen type XIII trimer(GO:0005600) transmembrane collagen trimer(GO:0030936)
0.0 0.1 GO:0005958 DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958)
0.0 0.2 GO:0033391 chromatoid body(GO:0033391)
0.0 0.3 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.1 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.0 0.1 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.0 1.3 GO:0018995 host(GO:0018995) host cell(GO:0043657)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.3 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.1 0.9 GO:0031386 protein tag(GO:0031386)
0.1 0.2 GO:0009041 uridylate kinase activity(GO:0009041)
0.0 0.1 GO:0030626 U12 snRNA binding(GO:0030626)
0.0 0.0 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.0 0.2 GO:0061133 endopeptidase activator activity(GO:0061133)
0.0 0.1 GO:0004583 dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity(GO:0004583)
0.0 0.1 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.0 0.1 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.0 0.2 GO:0042296 ISG15 transferase activity(GO:0042296)
0.0 0.1 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.0 0.9 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.1 GO:0016413 O-acetyltransferase activity(GO:0016413)
0.0 0.1 GO:0005019 platelet-derived growth factor beta-receptor activity(GO:0005019)
0.0 0.2 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.0 0.0 GO:0042007 interleukin-18 binding(GO:0042007)
0.0 0.1 GO:0004924 oncostatin-M receptor activity(GO:0004924)
0.0 0.0 GO:0030272 5-formyltetrahydrofolate cyclo-ligase activity(GO:0030272)
0.0 0.1 GO:0008079 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.0 0.5 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.1 GO:0008426 protein kinase C inhibitor activity(GO:0008426)
0.0 0.2 GO:0050693 LBD domain binding(GO:0050693)
0.0 0.1 GO:0005143 interleukin-12 receptor binding(GO:0005143)
0.0 0.1 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.0 0.1 GO:0001601 peptide YY receptor activity(GO:0001601)
0.0 0.0 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.0 0.1 GO:0035500 MH2 domain binding(GO:0035500)
0.0 0.1 GO:0034046 poly(G) binding(GO:0034046)
0.0 0.6 GO:0000983 transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
0.0 0.1 GO:0004329 formate-tetrahydrofolate ligase activity(GO:0004329)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 7.9 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.1 0.2 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.0 0.6 REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.0 0.5 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling