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SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for IRX3

Z-value: 1.21

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Transcription factors associated with IRX3

Gene Symbol Gene ID Gene Info
IRX3
ENSG00000177508.11 iroquois homeobox 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
IRX3hg19_v2_chr16_-_54320675_54320715-0.836.2e-06Click!

Activity profile of IRX3 motif

Sorted Z-values of IRX3 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr5_+_147443534 4.66 ENST00000398454.1
ENST00000359874.3
ENST00000508733.1
ENST00000256084.7
SPINK5
serine peptidase inhibitor, Kazal type 5
chr3_+_122044084 4.19 ENST00000264474.3
ENST00000479204.1
CSTA
cystatin A (stefin A)
chr2_-_113594279 3.91 ENST00000416750.1
ENST00000418817.1
ENST00000263341.2
IL1B
interleukin 1, beta
chr12_-_52867569 3.84 ENST00000252250.6
KRT6C
keratin 6C
chr12_+_76653611 3.63 ENST00000550380.1
RP11-54A9.1
RP11-54A9.1
chr1_+_87012753 3.52 ENST00000370563.3
CLCA4
chloride channel accessory 4
chr12_+_76653682 2.96 ENST00000553247.1
RP11-54A9.1
RP11-54A9.1
chr1_-_153029980 2.84 ENST00000392653.2
SPRR2A
small proline-rich protein 2A
chr11_+_57365150 2.80 ENST00000457869.1
ENST00000340687.6
ENST00000378323.4
ENST00000378324.2
ENST00000403558.1
SERPING1
serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
chr2_+_113885138 2.73 ENST00000409930.3
IL1RN
interleukin 1 receptor antagonist
chr13_-_38172863 2.69 ENST00000541481.1
ENST00000379743.4
ENST00000379742.4
ENST00000379749.4
ENST00000541179.1
ENST00000379747.4
POSTN
periostin, osteoblast specific factor
chr18_-_28622774 2.67 ENST00000434452.1
DSC3
desmocollin 3
chr4_+_100737954 2.62 ENST00000296414.7
ENST00000512369.1
DAPP1
dual adaptor of phosphotyrosine and 3-phosphoinositides
chr7_+_40174565 2.62 ENST00000309930.5
ENST00000401647.2
ENST00000335693.4
ENST00000413931.1
ENST00000416370.1
ENST00000540834.1
C7orf10
succinylCoA:glutarate-CoA transferase
chr7_+_144052381 2.61 ENST00000498580.1
ENST00000056217.5
ARHGEF5
Rho guanine nucleotide exchange factor (GEF) 5
chr12_-_28125638 2.48 ENST00000545234.1
PTHLH
parathyroid hormone-like hormone
chr6_+_106988986 2.39 ENST00000457437.1
ENST00000535438.1
AIM1
absent in melanoma 1
chr11_-_104905840 2.36 ENST00000526568.1
ENST00000393136.4
ENST00000531166.1
ENST00000534497.1
ENST00000527979.1
ENST00000446369.1
ENST00000353247.5
ENST00000528974.1
ENST00000533400.1
ENST00000525825.1
ENST00000436863.3
CASP1
caspase 1, apoptosis-related cysteine peptidase
chr6_-_47009996 2.20 ENST00000371243.2
GPR110
G protein-coupled receptor 110
chrX_+_99899180 2.16 ENST00000373004.3
SRPX2
sushi-repeat containing protein, X-linked 2
chr18_+_21529811 2.14 ENST00000588004.1
LAMA3
laminin, alpha 3
chr17_-_33760164 2.13 ENST00000445092.1
ENST00000394562.1
ENST00000447040.2
SLFN12
schlafen family member 12
chr7_-_41742697 2.07 ENST00000242208.4
INHBA
inhibin, beta A
chr3_-_93747425 1.97 ENST00000315099.2
STX19
syntaxin 19
chr7_-_143892748 1.90 ENST00000378115.2
ARHGEF35
Rho guanine nucleotide exchange factor (GEF) 35
chr1_-_89488510 1.86 ENST00000564665.1
ENST00000370481.4
GBP3
guanylate binding protein 3
chr8_-_125577940 1.84 ENST00000519168.1
ENST00000395508.2
MTSS1
metastasis suppressor 1
chr2_-_16804320 1.83 ENST00000355549.2
FAM49A
family with sequence similarity 49, member A
chr1_+_158979686 1.83 ENST00000368132.3
ENST00000295809.7
IFI16
interferon, gamma-inducible protein 16
chr1_+_87012922 1.79 ENST00000263723.5
CLCA4
chloride channel accessory 4
chr6_-_26216872 1.75 ENST00000244601.3
HIST1H2BG
histone cluster 1, H2bg
chr6_-_32634425 1.71 ENST00000399082.3
ENST00000399079.3
ENST00000374943.4
ENST00000434651.2
HLA-DQB1
major histocompatibility complex, class II, DQ beta 1
chr10_+_118187379 1.70 ENST00000369230.3
PNLIPRP3
pancreatic lipase-related protein 3
chr11_-_63330842 1.68 ENST00000255695.1
HRASLS2
HRAS-like suppressor 2
chr9_-_21975088 1.66 ENST00000304494.5
CDKN2A
cyclin-dependent kinase inhibitor 2A
chr5_+_31193847 1.65 ENST00000514738.1
ENST00000265071.2
CDH6
cadherin 6, type 2, K-cadherin (fetal kidney)
chr1_+_160709055 1.63 ENST00000368043.3
ENST00000368042.3
ENST00000458602.2
ENST00000458104.2
SLAMF7
SLAM family member 7
chr18_-_61329118 1.62 ENST00000332821.8
ENST00000283752.5
SERPINB3
serpin peptidase inhibitor, clade B (ovalbumin), member 3
chr1_-_230513367 1.61 ENST00000321327.2
ENST00000525115.1
PGBD5
piggyBac transposable element derived 5
chr4_+_69313145 1.60 ENST00000305363.4
TMPRSS11E
transmembrane protease, serine 11E
chr6_-_32784687 1.56 ENST00000447394.1
ENST00000438763.2
HLA-DOB
major histocompatibility complex, class II, DO beta
chr19_-_5851442 1.55 ENST00000458379.2
ENST00000589714.1
ENST00000589918.1
ENST00000303225.6
ENST00000589620.1
FUT3
fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis blood group)
chr12_-_10007448 1.50 ENST00000538152.1
CLEC2B
C-type lectin domain family 2, member B
chr1_+_158985457 1.47 ENST00000567661.1
ENST00000474473.1
IFI16
interferon, gamma-inducible protein 16
chr11_-_46113756 1.45 ENST00000531959.1
PHF21A
PHD finger protein 21A
chr19_-_20748541 1.44 ENST00000427401.4
ENST00000594419.1
ZNF737
zinc finger protein 737
chr1_+_31883048 1.41 ENST00000536859.1
SERINC2
serine incorporator 2
chr10_+_127661942 1.40 ENST00000417114.1
ENST00000445510.1
ENST00000368691.1
FANK1
fibronectin type III and ankyrin repeat domains 1
chr14_-_23623577 1.40 ENST00000422941.2
ENST00000453702.1
SLC7A8
solute carrier family 7 (amino acid transporter light chain, L system), member 8
chr11_+_35211429 1.36 ENST00000525688.1
ENST00000278385.6
ENST00000533222.1
CD44
CD44 molecule (Indian blood group)
chr11_-_87908600 1.36 ENST00000531138.1
ENST00000526372.1
ENST00000243662.6
RAB38
RAB38, member RAS oncogene family
chr11_+_12308447 1.30 ENST00000256186.2
MICALCL
MICAL C-terminal like
chr14_-_23624511 1.28 ENST00000529705.2
SLC7A8
solute carrier family 7 (amino acid transporter light chain, L system), member 8
chr6_-_75828774 1.26 ENST00000493109.2
COL12A1
collagen, type XII, alpha 1
chr1_+_152975488 1.26 ENST00000542696.1
SPRR3
small proline-rich protein 3
chr4_+_144312659 1.25 ENST00000509992.1
GAB1
GRB2-associated binding protein 1
chr9_+_135937365 1.24 ENST00000372080.4
ENST00000351304.7
CEL
carboxyl ester lipase
chr11_+_32851487 1.23 ENST00000257836.3
PRRG4
proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)
chr11_-_111782696 1.22 ENST00000227251.3
ENST00000526180.1
CRYAB
crystallin, alpha B
chr11_+_35201826 1.22 ENST00000531873.1
CD44
CD44 molecule (Indian blood group)
chr6_-_41130914 1.17 ENST00000373113.3
ENST00000338469.3
TREM2
triggering receptor expressed on myeloid cells 2
chr19_+_55591743 1.17 ENST00000588359.1
ENST00000245618.5
EPS8L1
EPS8-like 1
chr5_+_35856951 1.17 ENST00000303115.3
ENST00000343305.4
ENST00000506850.1
ENST00000511982.1
IL7R
interleukin 7 receptor
chr5_+_81601166 1.15 ENST00000439350.1
ATP6AP1L
ATPase, H+ transporting, lysosomal accessory protein 1-like
chr17_+_25958174 1.15 ENST00000313648.6
ENST00000577392.1
ENST00000584661.1
ENST00000413914.2
LGALS9
lectin, galactoside-binding, soluble, 9
chr1_-_46598371 1.15 ENST00000372006.1
ENST00000425892.1
ENST00000420542.1
ENST00000354242.4
ENST00000340332.6
PIK3R3
phosphoinositide-3-kinase, regulatory subunit 3 (gamma)
chr3_+_177159695 1.15 ENST00000442937.1
LINC00578
long intergenic non-protein coding RNA 578
chr4_-_143481822 1.14 ENST00000510812.1
INPP4B
inositol polyphosphate-4-phosphatase, type II, 105kDa
chr4_-_83769996 1.13 ENST00000511338.1
SEC31A
SEC31 homolog A (S. cerevisiae)
chr1_+_160709029 1.13 ENST00000444090.2
ENST00000441662.2
SLAMF7
SLAM family member 7
chr13_-_46716969 1.09 ENST00000435666.2
LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr3_-_176915215 1.09 ENST00000457928.2
ENST00000422442.1
TBL1XR1
transducin (beta)-like 1 X-linked receptor 1
chr1_+_77333117 1.08 ENST00000477717.1
ST6GALNAC5
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5
chr12_+_106751436 1.08 ENST00000228347.4
POLR3B
polymerase (RNA) III (DNA directed) polypeptide B
chr19_+_53761545 1.07 ENST00000341702.3
VN1R2
vomeronasal 1 receptor 2
chr3_+_171561127 1.07 ENST00000334567.5
ENST00000450693.1
TMEM212
transmembrane protein 212
chr14_+_72052983 1.07 ENST00000358550.2
SIPA1L1
signal-induced proliferation-associated 1 like 1
chr4_-_70725856 1.06 ENST00000226444.3
SULT1E1
sulfotransferase family 1E, estrogen-preferring, member 1
chr12_-_91546926 1.05 ENST00000550758.1
DCN
decorin
chr1_-_46598284 1.02 ENST00000423209.1
ENST00000262741.5
PIK3R3
phosphoinositide-3-kinase, regulatory subunit 3 (gamma)
chr4_+_185734773 1.02 ENST00000508020.1
RP11-701P16.2
Uncharacterized protein
chr17_-_33760269 1.01 ENST00000452764.3
SLFN12
schlafen family member 12
chr19_-_20844368 0.97 ENST00000595094.1
ENST00000601440.1
ENST00000291750.6
CTC-513N18.7
ZNF626
CTC-513N18.7
zinc finger protein 626
chr1_+_160709076 0.97 ENST00000359331.4
ENST00000495334.1
SLAMF7
SLAM family member 7
chr11_-_104972158 0.96 ENST00000598974.1
ENST00000593315.1
ENST00000594519.1
ENST00000415981.2
ENST00000525374.1
ENST00000375707.1
CASP1
CARD16
CARD17
caspase 1, apoptosis-related cysteine peptidase
caspase recruitment domain family, member 16
caspase recruitment domain family, member 17
chr4_+_56212505 0.96 ENST00000505210.1
SRD5A3
steroid 5 alpha-reductase 3
chr21_+_42733870 0.94 ENST00000330714.3
ENST00000436410.1
ENST00000435611.1
MX2
myxovirus (influenza virus) resistance 2 (mouse)
chr4_+_75480629 0.93 ENST00000380846.3
AREGB
amphiregulin B
chr5_-_95297678 0.93 ENST00000237853.4
ELL2
elongation factor, RNA polymerase II, 2
chr7_-_92777606 0.90 ENST00000437805.1
ENST00000446959.1
ENST00000439952.1
ENST00000414791.1
ENST00000446033.1
ENST00000411955.1
ENST00000318238.4
SAMD9L
sterile alpha motif domain containing 9-like
chr6_-_79944336 0.89 ENST00000344726.5
ENST00000275036.7
HMGN3
high mobility group nucleosomal binding domain 3
chr3_+_14058794 0.88 ENST00000424053.1
ENST00000528067.1
ENST00000429201.1
TPRXL
tetra-peptide repeat homeobox-like
chr1_-_31902614 0.88 ENST00000596131.1
AC114494.1
HCG1787699; Uncharacterized protein
chr4_-_83812402 0.87 ENST00000395310.2
SEC31A
SEC31 homolog A (S. cerevisiae)
chrX_+_150866779 0.87 ENST00000370353.3
PRRG3
proline rich Gla (G-carboxyglutamic acid) 3 (transmembrane)
chr2_+_119699864 0.87 ENST00000541757.1
ENST00000412481.1
MARCO
macrophage receptor with collagenous structure
chr8_-_101724989 0.86 ENST00000517403.1
PABPC1
poly(A) binding protein, cytoplasmic 1
chr15_-_81616446 0.86 ENST00000302824.6
STARD5
StAR-related lipid transfer (START) domain containing 5
chr3_-_74570291 0.85 ENST00000263665.6
CNTN3
contactin 3 (plasmacytoma associated)
chr4_+_71600144 0.85 ENST00000502653.1
RUFY3
RUN and FYVE domain containing 3
chr19_-_20748614 0.85 ENST00000596797.1
ZNF737
zinc finger protein 737
chr3_-_149510553 0.84 ENST00000462519.2
ENST00000446160.1
ENST00000383050.3
ANKUB1
ankyrin repeat and ubiquitin domain containing 1
chr1_-_153066998 0.84 ENST00000368750.3
SPRR2E
small proline-rich protein 2E
chr3_-_160823040 0.83 ENST00000484127.1
ENST00000492353.1
ENST00000473142.1
ENST00000468268.1
ENST00000460353.1
ENST00000320474.4
ENST00000392781.2
B3GALNT1
beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group)
chr8_-_145060593 0.83 ENST00000313059.5
ENST00000524918.1
ENST00000313028.7
ENST00000525773.1
PARP10
poly (ADP-ribose) polymerase family, member 10
chr6_+_26217159 0.82 ENST00000303910.2
HIST1H2AE
histone cluster 1, H2ae
chr17_+_18380051 0.82 ENST00000581545.1
ENST00000582333.1
ENST00000328114.6
ENST00000412421.2
ENST00000583322.1
ENST00000584941.1
LGALS9C
lectin, galactoside-binding, soluble, 9C
chr2_-_88125471 0.82 ENST00000398146.3
RGPD2
RANBP2-like and GRIP domain containing 2
chr3_-_49851313 0.82 ENST00000333486.3
UBA7
ubiquitin-like modifier activating enzyme 7
chr11_-_35547572 0.81 ENST00000378880.2
PAMR1
peptidase domain containing associated with muscle regeneration 1
chr2_+_182850551 0.80 ENST00000452904.1
ENST00000409137.3
ENST00000280295.3
PPP1R1C
protein phosphatase 1, regulatory (inhibitor) subunit 1C
chr22_-_36556821 0.80 ENST00000531095.1
ENST00000397293.2
ENST00000349314.2
APOL3
apolipoprotein L, 3
chr13_+_21714653 0.79 ENST00000382533.4
SAP18
Sin3A-associated protein, 18kDa
chr3_+_156799587 0.78 ENST00000469196.1
RP11-6F2.5
RP11-6F2.5
chr11_-_61647935 0.77 ENST00000531956.1
FADS3
fatty acid desaturase 3
chr2_-_231090344 0.77 ENST00000540870.1
ENST00000416610.1
SP110
SP110 nuclear body protein
chr1_+_196788887 0.77 ENST00000320493.5
ENST00000367424.4
ENST00000367421.3
CFHR1
CFHR2
complement factor H-related 1
complement factor H-related 2
chr2_+_113816215 0.76 ENST00000346807.3
IL36RN
interleukin 36 receptor antagonist
chr8_+_24151620 0.76 ENST00000437154.2
ADAM28
ADAM metallopeptidase domain 28
chrX_-_55291163 0.76 ENST00000519203.1
ENST00000374951.1
PAGE3
P antigen family, member 3 (prostate associated)
chr6_-_138833630 0.76 ENST00000533765.1
NHSL1
NHS-like 1
chr6_+_63921399 0.75 ENST00000356170.3
FKBP1C
FK506 binding protein 1C
chr7_-_99063769 0.75 ENST00000394186.3
ENST00000359832.4
ENST00000449683.1
ENST00000488775.1
ENST00000523680.1
ENST00000292475.3
ENST00000430982.1
ENST00000555673.1
ENST00000413834.1
ATP5J2
PTCD1
ATP5J2-PTCD1
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F2
pentatricopeptide repeat domain 1
ATP5J2-PTCD1 readthrough
chr2_+_182850743 0.75 ENST00000409702.1
PPP1R1C
protein phosphatase 1, regulatory (inhibitor) subunit 1C
chr10_+_13628921 0.74 ENST00000378572.3
PRPF18
pre-mRNA processing factor 18
chr11_-_125773085 0.74 ENST00000227474.3
ENST00000534158.1
ENST00000529801.1
PUS3
pseudouridylate synthase 3
chr6_+_37012607 0.74 ENST00000423336.1
COX6A1P2
cytochrome c oxidase subunit VIa polypeptide 1 pseudogene 2
chr11_-_111782484 0.73 ENST00000533971.1
CRYAB
crystallin, alpha B
chr20_+_54933971 0.73 ENST00000371384.3
ENST00000437418.1
FAM210B
family with sequence similarity 210, member B
chr4_+_71600063 0.73 ENST00000513597.1
RUFY3
RUN and FYVE domain containing 3
chr5_-_64064508 0.72 ENST00000513458.4
SREK1IP1
SREK1-interacting protein 1
chr8_-_97247759 0.72 ENST00000518406.1
ENST00000523920.1
ENST00000287022.5
UQCRB
ubiquinol-cytochrome c reductase binding protein
chr14_-_21737551 0.71 ENST00000554891.1
ENST00000555883.1
ENST00000553753.1
ENST00000555914.1
ENST00000557336.1
ENST00000555215.1
ENST00000556628.1
ENST00000555137.1
ENST00000556226.1
ENST00000555309.1
ENST00000556142.1
ENST00000554969.1
ENST00000554455.1
ENST00000556513.1
ENST00000557201.1
ENST00000420743.2
ENST00000557768.1
ENST00000553300.1
ENST00000554383.1
ENST00000554539.1
HNRNPC
heterogeneous nuclear ribonucleoprotein C (C1/C2)
chr3_+_101659682 0.70 ENST00000465215.1
RP11-221J22.1
RP11-221J22.1
chr1_+_46152886 0.69 ENST00000372025.4
TMEM69
transmembrane protein 69
chr7_+_6713376 0.69 ENST00000399484.3
ENST00000544825.1
ENST00000401847.1
AC073343.1
Uncharacterized protein
chr6_+_42584847 0.69 ENST00000372883.3
UBR2
ubiquitin protein ligase E3 component n-recognin 2
chr18_+_32173276 0.68 ENST00000591816.1
ENST00000588125.1
ENST00000598334.1
ENST00000588684.1
ENST00000554864.3
ENST00000399121.5
ENST00000595022.1
ENST00000269190.7
ENST00000399097.3
DTNA
dystrobrevin, alpha
chr13_+_73629107 0.68 ENST00000539231.1
KLF5
Kruppel-like factor 5 (intestinal)
chr3_-_160823158 0.68 ENST00000392779.2
ENST00000392780.1
ENST00000494173.1
B3GALNT1
beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group)
chr20_-_36156125 0.68 ENST00000397135.1
ENST00000397137.1
BLCAP
bladder cancer associated protein
chr15_+_25200074 0.67 ENST00000390687.4
ENST00000584968.1
ENST00000346403.6
ENST00000554227.2
SNRPN
small nuclear ribonucleoprotein polypeptide N
chr11_-_62477313 0.67 ENST00000464544.1
ENST00000530009.1
BSCL2
Berardinelli-Seip congenital lipodystrophy 2 (seipin)
chr10_+_13628933 0.66 ENST00000417658.1
ENST00000320054.4
PRPF18
pre-mRNA processing factor 18
chr12_-_10542617 0.65 ENST00000240618.6
KLRK1
killer cell lectin-like receptor subfamily K, member 1
chr3_-_196987309 0.65 ENST00000453607.1
DLG1
discs, large homolog 1 (Drosophila)
chr1_+_144173162 0.65 ENST00000356801.6
NBPF8
neuroblastoma breakpoint family, member 8
chr2_+_170440902 0.64 ENST00000448752.2
ENST00000418888.1
ENST00000414307.1
PPIG
peptidylprolyl isomerase G (cyclophilin G)
chr4_-_69434245 0.64 ENST00000317746.2
UGT2B17
UDP glucuronosyltransferase 2 family, polypeptide B17
chr6_-_32145861 0.64 ENST00000336984.6
AGPAT1
1-acylglycerol-3-phosphate O-acyltransferase 1
chr19_-_44952635 0.64 ENST00000592308.1
ENST00000588931.1
ENST00000291187.4
ZNF229
zinc finger protein 229
chr8_+_52730143 0.63 ENST00000415643.1
AC090186.1
Uncharacterized protein
chrX_-_15620192 0.63 ENST00000427411.1
ACE2
angiotensin I converting enzyme 2
chr19_-_38085633 0.62 ENST00000593133.1
ENST00000590751.1
ENST00000358744.3
ENST00000328550.2
ENST00000451802.2
ZNF571
zinc finger protein 571
chr17_-_71410794 0.62 ENST00000424778.1
SDK2
sidekick cell adhesion molecule 2
chr19_+_58545369 0.61 ENST00000391700.1
ZSCAN1
zinc finger and SCAN domain containing 1
chr3_+_177159744 0.61 ENST00000439009.1
LINC00578
long intergenic non-protein coding RNA 578
chr19_+_20959098 0.61 ENST00000360204.5
ENST00000594534.1
ZNF66
zinc finger protein 66
chr6_-_112081113 0.61 ENST00000517419.1
FYN
FYN oncogene related to SRC, FGR, YES
chr13_+_25254693 0.60 ENST00000381946.3
ATP12A
ATPase, H+/K+ transporting, nongastric, alpha polypeptide
chr16_+_48657361 0.60 ENST00000565072.1
RP11-42I10.1
RP11-42I10.1
chr19_+_16940198 0.60 ENST00000248054.5
ENST00000596802.1
ENST00000379803.1
SIN3B
SIN3 transcription regulator family member B
chr6_-_26199499 0.60 ENST00000377831.5
HIST1H3D
histone cluster 1, H3d
chr8_+_94767072 0.59 ENST00000452276.1
ENST00000453321.3
ENST00000498673.1
ENST00000518319.1
TMEM67
transmembrane protein 67
chr5_+_125800836 0.59 ENST00000511134.1
GRAMD3
GRAM domain containing 3
chr19_-_22379753 0.59 ENST00000397121.2
ZNF676
zinc finger protein 676
chr2_+_170440844 0.59 ENST00000260970.3
ENST00000433207.1
ENST00000409714.3
ENST00000462903.1
PPIG
peptidylprolyl isomerase G (cyclophilin G)
chr3_-_187455680 0.58 ENST00000438077.1
BCL6
B-cell CLL/lymphoma 6
chr19_+_58193388 0.58 ENST00000596085.1
ENST00000594684.1
ZNF551
AC003006.7
zinc finger protein 551
Uncharacterized protein
chr15_+_92006567 0.58 ENST00000554333.1
RP11-661P17.1
RP11-661P17.1
chr10_-_61122220 0.58 ENST00000422313.2
ENST00000435852.2
ENST00000442566.3
ENST00000373868.2
ENST00000277705.6
ENST00000373867.3
ENST00000419214.2
FAM13C
family with sequence similarity 13, member C
chr4_+_74606223 0.58 ENST00000307407.3
ENST00000401931.1
IL8
interleukin 8
chr4_-_39460496 0.57 ENST00000449470.2
RPL9
ribosomal protein L9
chr19_+_7580103 0.57 ENST00000596712.1
ZNF358
zinc finger protein 358
chr14_-_67878917 0.57 ENST00000216446.4
PLEK2
pleckstrin 2
chr5_-_115872124 0.57 ENST00000515009.1
SEMA6A
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
chr17_+_74846230 0.57 ENST00000592919.1
LINC00868
long intergenic non-protein coding RNA 868
chr13_+_25254545 0.56 ENST00000218548.6
ATP12A
ATPase, H+/K+ transporting, nongastric, alpha polypeptide
chr4_-_153332886 0.56 ENST00000603841.1
FBXW7
F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
chr1_-_148025848 0.56 ENST00000310701.10
ENST00000369219.1
ENST00000444640.1
ENST00000431121.1
ENST00000436356.1
ENST00000448574.1
ENST00000458135.1
ENST00000392972.3
ENST00000426874.1
NBPF14
neuroblastoma breakpoint family, member 14
chrX_-_30993201 0.56 ENST00000288422.2
ENST00000378932.2
TAB3
TGF-beta activated kinase 1/MAP3K7 binding protein 3
chr8_+_55466915 0.55 ENST00000522711.2
RP11-53M11.3
RP11-53M11.3
chr11_-_14358620 0.55 ENST00000531421.1
RRAS2
related RAS viral (r-ras) oncogene homolog 2
chr1_+_46668994 0.55 ENST00000371980.3
LURAP1
leucine rich adaptor protein 1
chr1_+_160175201 0.55 ENST00000368076.1
PEA15
phosphoprotein enriched in astrocytes 15
chr2_+_234621551 0.54 ENST00000608381.1
ENST00000373414.3
UGT1A1
UGT1A5
UDP glucuronosyltransferase 1 family, polypeptide A8
UDP glucuronosyltransferase 1 family, polypeptide A5
chr6_-_26199471 0.54 ENST00000341023.1
HIST1H2AD
histone cluster 1, H2ad
chr4_+_75310851 0.54 ENST00000395748.3
ENST00000264487.2
AREG
amphiregulin
chr1_+_1846519 0.54 ENST00000378604.3
CALML6
calmodulin-like 6
chr5_-_115872142 0.54 ENST00000510263.1
SEMA6A
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
chr6_+_71104588 0.53 ENST00000418403.1
RP11-462G2.1
RP11-462G2.1
chr16_+_22524844 0.53 ENST00000538606.1
ENST00000424340.1
ENST00000517539.1
ENST00000528249.1
NPIPB5
nuclear pore complex interacting protein family, member B5
chr11_+_114310102 0.53 ENST00000265881.5
REXO2
RNA exonuclease 2
chr15_+_25200108 0.52 ENST00000577949.1
ENST00000338094.6
ENST00000338327.4
ENST00000579070.1
ENST00000577565.1
SNURF
SNRPN
SNRPN upstream reading frame protein
small nuclear ribonucleoprotein polypeptide N
chr1_+_28655505 0.52 ENST00000373842.4
ENST00000398997.2
MED18
mediator complex subunit 18
chr5_-_132073210 0.52 ENST00000378735.1
ENST00000378746.4
KIF3A
kinesin family member 3A
chr10_-_96829246 0.52 ENST00000371270.3
ENST00000535898.1
ENST00000539050.1
CYP2C8
cytochrome P450, family 2, subfamily C, polypeptide 8
chr4_-_83765613 0.52 ENST00000503937.1
SEC31A
SEC31 homolog A (S. cerevisiae)
chr11_-_134123142 0.52 ENST00000392595.2
ENST00000341541.3
ENST00000352327.5
ENST00000392594.3
THYN1
thymocyte nuclear protein 1
chr19_-_9092018 0.51 ENST00000397910.4
MUC16
mucin 16, cell surface associated

Network of associatons between targets according to the STRING database.

First level regulatory network of IRX3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 3.3 GO:0050717 positive regulation of interleukin-1 alpha secretion(GO:0050717)
0.7 2.1 GO:0060278 regulation of ovulation(GO:0060278) positive regulation of ovulation(GO:0060279)
0.7 4.7 GO:0002786 regulation of antimicrobial peptide production(GO:0002784) regulation of antibacterial peptide production(GO:0002786)
0.5 2.7 GO:0002586 regulation of antigen processing and presentation of peptide antigen via MHC class II(GO:0002586)
0.5 6.5 GO:0070487 monocyte aggregation(GO:0070487)
0.5 1.5 GO:0006711 estrogen catabolic process(GO:0006711)
0.5 1.4 GO:0071048 nuclear mRNA surveillance of spliceosomal pre-mRNA splicing(GO:0071030) nuclear retention of unspliced pre-mRNA at the site of transcription(GO:0071048)
0.4 2.7 GO:0032571 response to vitamin K(GO:0032571) regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904207) positive regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904209) bone regeneration(GO:1990523)
0.4 1.6 GO:0035425 autocrine signaling(GO:0035425)
0.4 1.2 GO:0002519 natural killer cell tolerance induction(GO:0002519) positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:2001190)
0.3 2.9 GO:2000660 negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
0.3 1.8 GO:0030035 microspike assembly(GO:0030035)
0.2 1.2 GO:0044240 multicellular organism lipid catabolic process(GO:0044240)
0.2 2.7 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.2 1.4 GO:1904219 regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) positive regulation of serine C-palmitoyltransferase activity(GO:1904222)
0.2 0.7 GO:2000502 negative regulation of natural killer cell chemotaxis(GO:2000502)
0.2 1.4 GO:1903232 melanosome assembly(GO:1903232)
0.2 0.8 GO:0010847 regulation of chromatin assembly(GO:0010847) protein auto-ADP-ribosylation(GO:0070213)
0.2 3.7 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.1 0.7 GO:0070980 biphenyl catabolic process(GO:0070980)
0.1 0.3 GO:2001027 negative regulation of endothelial cell chemotaxis(GO:2001027)
0.1 0.6 GO:0032764 negative regulation of mast cell cytokine production(GO:0032764) negative regulation of isotype switching to IgE isotypes(GO:0048294)
0.1 0.4 GO:0061300 cerebellum vasculature development(GO:0061300)
0.1 0.4 GO:0021503 neural fold bending(GO:0021503)
0.1 1.7 GO:0035986 senescence-associated heterochromatin focus assembly(GO:0035986)
0.1 0.7 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.1 1.0 GO:0019348 dolichol metabolic process(GO:0019348)
0.1 0.4 GO:0019254 amino-acid betaine catabolic process(GO:0006579) carnitine metabolic process, CoA-linked(GO:0019254)
0.1 1.1 GO:0019236 response to pheromone(GO:0019236)
0.1 3.7 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.1 0.6 GO:0003051 angiotensin-mediated drinking behavior(GO:0003051)
0.1 0.4 GO:0006533 aspartate catabolic process(GO:0006533)
0.1 0.2 GO:0032765 positive regulation of mast cell cytokine production(GO:0032765)
0.1 2.5 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.1 0.6 GO:2000638 regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
0.1 0.3 GO:0016256 N-glycan processing to lysosome(GO:0016256)
0.1 0.7 GO:1990481 mRNA pseudouridine synthesis(GO:1990481)
0.1 2.2 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.1 8.0 GO:0018149 peptide cross-linking(GO:0018149)
0.1 1.0 GO:0045919 positive regulation of cytolysis(GO:0045919)
0.1 1.2 GO:0001915 negative regulation of T cell mediated cytotoxicity(GO:0001915)
0.1 0.8 GO:1902714 antifungal humoral response(GO:0019732) negative regulation of interferon-gamma secretion(GO:1902714)
0.1 0.5 GO:0071874 cellular response to norepinephrine stimulus(GO:0071874)
0.1 0.5 GO:0009107 lipoate biosynthetic process(GO:0009107)
0.1 0.5 GO:0010751 negative regulation of nitric oxide mediated signal transduction(GO:0010751)
0.1 0.3 GO:0032290 peripheral nervous system myelin formation(GO:0032290)
0.1 0.3 GO:0018874 benzoate metabolic process(GO:0018874)
0.1 0.8 GO:2001206 positive regulation of osteoclast development(GO:2001206)
0.1 0.6 GO:1901297 positive regulation of ephrin receptor signaling pathway(GO:1901189) positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068)
0.1 1.3 GO:0046325 negative regulation of glucose import(GO:0046325)
0.1 0.7 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.1 2.7 GO:0015695 organic cation transport(GO:0015695)
0.1 0.5 GO:0002933 lipid hydroxylation(GO:0002933)
0.1 1.1 GO:0060613 fat pad development(GO:0060613)
0.1 0.9 GO:2000622 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.1 0.7 GO:0097033 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.1 0.9 GO:1900029 positive regulation of ruffle assembly(GO:1900029)
0.1 0.3 GO:0046726 positive regulation by virus of viral protein levels in host cell(GO:0046726)
0.1 0.4 GO:0032383 regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
0.1 0.3 GO:0035616 histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.1 3.8 GO:0045104 intermediate filament cytoskeleton organization(GO:0045104)
0.1 0.8 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.1 0.3 GO:0038155 interleukin-23-mediated signaling pathway(GO:0038155)
0.1 2.5 GO:0032331 negative regulation of chondrocyte differentiation(GO:0032331)
0.1 0.6 GO:1903764 regulation of potassium ion export across plasma membrane(GO:1903764)
0.1 0.8 GO:0035457 cellular response to interferon-alpha(GO:0035457)
0.1 0.3 GO:1904693 midbrain morphogenesis(GO:1904693)
0.1 2.3 GO:2001275 positive regulation of glucose import in response to insulin stimulus(GO:2001275)
0.1 0.6 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
0.1 0.9 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.1 2.1 GO:0031581 hemidesmosome assembly(GO:0031581)
0.1 0.8 GO:0097475 motor neuron migration(GO:0097475)
0.1 0.2 GO:0033686 positive regulation of luteinizing hormone secretion(GO:0033686)
0.1 0.1 GO:0006883 cellular sodium ion homeostasis(GO:0006883)
0.1 0.5 GO:0060744 thelarche(GO:0042695) mammary gland branching involved in thelarche(GO:0060744)
0.1 0.4 GO:0043950 positive regulation of cAMP-mediated signaling(GO:0043950)
0.1 0.2 GO:0035397 helper T cell enhancement of adaptive immune response(GO:0035397)
0.1 0.3 GO:0002071 glandular epithelial cell maturation(GO:0002071) type B pancreatic cell maturation(GO:0072560)
0.1 0.4 GO:2000490 negative regulation of hepatic stellate cell activation(GO:2000490)
0.1 3.6 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.0 1.2 GO:0035376 sterol import(GO:0035376) cholesterol import(GO:0070508)
0.0 0.2 GO:0061763 multivesicular body-lysosome fusion(GO:0061763)
0.0 1.2 GO:0010248 establishment or maintenance of transmembrane electrochemical gradient(GO:0010248)
0.0 0.5 GO:0042780 tRNA 3'-end processing(GO:0042780)
0.0 0.4 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.0 1.8 GO:0035728 response to hepatocyte growth factor(GO:0035728)
0.0 4.1 GO:0042267 natural killer cell mediated cytotoxicity(GO:0042267)
0.0 0.2 GO:0042574 retinoic acid metabolic process(GO:0042573) retinal metabolic process(GO:0042574)
0.0 0.1 GO:0030505 inorganic diphosphate transport(GO:0030505)
0.0 0.9 GO:0035455 response to interferon-alpha(GO:0035455)
0.0 0.4 GO:0003383 apical constriction(GO:0003383)
0.0 1.6 GO:0032463 negative regulation of protein homooligomerization(GO:0032463)
0.0 1.7 GO:0036152 phosphatidylethanolamine acyl-chain remodeling(GO:0036152)
0.0 0.2 GO:0010966 regulation of phosphate transport(GO:0010966)
0.0 2.8 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.3 GO:0021691 cerebellar Purkinje cell layer maturation(GO:0021691)
0.0 0.6 GO:1902951 negative regulation of dendritic spine maintenance(GO:1902951)
0.0 0.5 GO:0070779 gamma-aminobutyric acid biosynthetic process(GO:0009449) D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.0 0.5 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.0 0.3 GO:0035063 nuclear speck organization(GO:0035063)
0.0 0.3 GO:0007341 penetration of zona pellucida(GO:0007341)
0.0 1.6 GO:2000114 regulation of establishment of cell polarity(GO:2000114)
0.0 0.3 GO:0098706 ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706)
0.0 0.4 GO:0042905 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.0 0.2 GO:0021784 postganglionic parasympathetic fiber development(GO:0021784)
0.0 0.7 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.0 0.2 GO:0036496 regulation of translational initiation by eIF2 alpha dephosphorylation(GO:0036496)
0.0 0.2 GO:1904885 beta-catenin destruction complex assembly(GO:1904885)
0.0 1.5 GO:1900087 positive regulation of G1/S transition of mitotic cell cycle(GO:1900087)
0.0 0.1 GO:0002331 pre-B cell allelic exclusion(GO:0002331)
0.0 0.3 GO:0006987 activation of signaling protein activity involved in unfolded protein response(GO:0006987)
0.0 0.3 GO:0070269 pyroptosis(GO:0070269)
0.0 0.5 GO:0034454 microtubule anchoring at centrosome(GO:0034454)
0.0 0.4 GO:1900246 positive regulation of RIG-I signaling pathway(GO:1900246)
0.0 0.1 GO:0044029 DNA hypomethylation(GO:0044028) hypomethylation of CpG island(GO:0044029)
0.0 0.3 GO:0086046 membrane depolarization during SA node cell action potential(GO:0086046)
0.0 0.2 GO:0003095 pressure natriuresis(GO:0003095)
0.0 0.1 GO:0002372 myeloid dendritic cell cytokine production(GO:0002372)
0.0 0.7 GO:2001224 positive regulation of neuron migration(GO:2001224)
0.0 0.9 GO:0036158 outer dynein arm assembly(GO:0036158)
0.0 0.5 GO:2000786 positive regulation of autophagosome assembly(GO:2000786)
0.0 0.1 GO:1902713 regulation of interferon-gamma secretion(GO:1902713)
0.0 0.4 GO:0098814 spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.0 0.8 GO:0060219 camera-type eye photoreceptor cell differentiation(GO:0060219)
0.0 0.3 GO:0033183 negative regulation of histone ubiquitination(GO:0033183) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315)
0.0 0.1 GO:0071029 exonucleolytic trimming involved in rRNA processing(GO:0000459) exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000467) U1 snRNA 3'-end processing(GO:0034473) U4 snRNA 3'-end processing(GO:0034475) U5 snRNA 3'-end processing(GO:0034476) polyadenylation-dependent RNA catabolic process(GO:0043633) polyadenylation-dependent ncRNA catabolic process(GO:0043634) nuclear ncRNA surveillance(GO:0071029) nuclear polyadenylation-dependent rRNA catabolic process(GO:0071035) nuclear polyadenylation-dependent tRNA catabolic process(GO:0071038) nuclear polyadenylation-dependent mRNA catabolic process(GO:0071042) nuclear polyadenylation-dependent ncRNA catabolic process(GO:0071046) polyadenylation-dependent mRNA catabolic process(GO:0071047)
0.0 5.4 GO:1902476 chloride transmembrane transport(GO:1902476)
0.0 0.2 GO:0014826 vein smooth muscle contraction(GO:0014826)
0.0 0.2 GO:0002027 regulation of heart rate(GO:0002027)
0.0 0.7 GO:1902603 carnitine shuttle(GO:0006853) carnitine transmembrane transport(GO:1902603)
0.0 0.1 GO:0060272 embryonic skeletal joint morphogenesis(GO:0060272)
0.0 0.1 GO:0043654 recognition of apoptotic cell(GO:0043654)
0.0 1.2 GO:0090662 ATP hydrolysis coupled proton transport(GO:0015991) ATP hydrolysis coupled transmembrane transport(GO:0090662)
0.0 0.1 GO:0070857 regulation of bile acid biosynthetic process(GO:0070857)
0.0 0.4 GO:0051957 positive regulation of amino acid transport(GO:0051957)
0.0 0.2 GO:0050773 regulation of dendrite development(GO:0050773)
0.0 0.3 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.0 0.2 GO:0097577 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.0 0.6 GO:0010826 negative regulation of centrosome duplication(GO:0010826)
0.0 3.3 GO:0070268 cornification(GO:0070268)
0.0 0.4 GO:0002098 tRNA wobble uridine modification(GO:0002098)
0.0 0.1 GO:0002818 intracellular defense response(GO:0002818)
0.0 0.3 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
0.0 0.6 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024)
0.0 0.2 GO:0021564 vagus nerve development(GO:0021564)
0.0 0.3 GO:2001013 epithelial cell proliferation involved in renal tubule morphogenesis(GO:2001013)
0.0 0.6 GO:0006020 inositol metabolic process(GO:0006020)
0.0 0.2 GO:0019626 short-chain fatty acid catabolic process(GO:0019626)
0.0 0.4 GO:0006662 glycerol ether metabolic process(GO:0006662)
0.0 1.1 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.0 0.1 GO:0007525 somatic muscle development(GO:0007525)
0.0 0.1 GO:0070173 regulation of enamel mineralization(GO:0070173)
0.0 0.1 GO:0042427 serotonin biosynthetic process(GO:0042427)
0.0 1.2 GO:0030262 apoptotic nuclear changes(GO:0030262)
0.0 0.7 GO:0034389 lipid particle organization(GO:0034389)
0.0 0.2 GO:0006740 NADPH regeneration(GO:0006740)
0.0 0.9 GO:0043277 apoptotic cell clearance(GO:0043277)
0.0 0.1 GO:0045200 establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200)
0.0 0.2 GO:0070307 lens fiber cell development(GO:0070307)
0.0 0.5 GO:0070935 3'-UTR-mediated mRNA stabilization(GO:0070935)
0.0 0.1 GO:0051832 evasion or tolerance of host defenses by virus(GO:0019049) transforming growth factor beta3 production(GO:0032907) regulation of transforming growth factor beta3 production(GO:0032910) positive regulation of transforming growth factor beta3 production(GO:0032916) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834) negative regulation of lung blood pressure(GO:0061767)
0.0 3.1 GO:0016575 histone deacetylation(GO:0016575)
0.0 0.4 GO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)
0.0 0.2 GO:0051597 response to methylmercury(GO:0051597)
0.0 1.2 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.0 0.1 GO:0061107 seminal vesicle development(GO:0061107)
0.0 0.3 GO:0072321 chaperone-mediated protein transport(GO:0072321)
0.0 0.1 GO:0048539 bone marrow development(GO:0048539)
0.0 0.2 GO:0035609 C-terminal protein deglutamylation(GO:0035609)
0.0 0.2 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.0 0.4 GO:0050962 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.0 0.1 GO:0017198 N-terminal peptidyl-serine acetylation(GO:0017198) N-terminal peptidyl-glutamic acid acetylation(GO:0018002) peptidyl-serine acetylation(GO:0030920)
0.0 0.2 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.0 0.1 GO:2000255 negative regulation of male germ cell proliferation(GO:2000255)
0.0 0.3 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.0 0.8 GO:0002755 MyD88-dependent toll-like receptor signaling pathway(GO:0002755)
0.0 0.1 GO:0097319 fructose transport(GO:0015755) fructose import(GO:0032445) carbohydrate import into cell(GO:0097319) carbohydrate import across plasma membrane(GO:0098704) fructose import across plasma membrane(GO:1990539)
0.0 0.3 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.0 0.1 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
0.0 0.6 GO:0001649 osteoblast differentiation(GO:0001649)
0.0 1.7 GO:0006501 C-terminal protein lipidation(GO:0006501)
0.0 0.2 GO:0045176 apical protein localization(GO:0045176)
0.0 0.3 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.0 0.6 GO:0035115 embryonic forelimb morphogenesis(GO:0035115)
0.0 0.2 GO:1900017 positive regulation of cytokine production involved in inflammatory response(GO:1900017)
0.0 1.6 GO:0031295 T cell costimulation(GO:0031295)
0.0 0.1 GO:0060235 lens induction in camera-type eye(GO:0060235)
0.0 0.2 GO:0000050 urea cycle(GO:0000050)
0.0 0.1 GO:0061470 T follicular helper cell differentiation(GO:0061470)
0.0 0.2 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 0.1 GO:0034201 response to oleic acid(GO:0034201)
0.0 0.7 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.0 0.0 GO:0001810 regulation of type I hypersensitivity(GO:0001810) positive regulation of type I hypersensitivity(GO:0001812) type I hypersensitivity(GO:0016068)
0.0 0.1 GO:0006937 regulation of muscle contraction(GO:0006937)
0.0 0.1 GO:0048194 Golgi vesicle budding(GO:0048194)
0.0 0.0 GO:1900044 regulation of protein K63-linked ubiquitination(GO:1900044)
0.0 0.0 GO:2000863 positive regulation of estrogen secretion(GO:2000863) positive regulation of estradiol secretion(GO:2000866)
0.0 0.0 GO:0033488 cholesterol biosynthetic process via 24,25-dihydrolanosterol(GO:0033488)
0.0 0.3 GO:0006044 N-acetylglucosamine metabolic process(GO:0006044)
0.0 0.3 GO:0036315 cellular response to sterol(GO:0036315)
0.0 0.2 GO:1903959 regulation of anion transmembrane transport(GO:1903959)
0.0 0.2 GO:2000675 negative regulation of type B pancreatic cell apoptotic process(GO:2000675)
0.0 0.4 GO:0000038 very long-chain fatty acid metabolic process(GO:0000038)
0.0 0.3 GO:0001702 gastrulation with mouth forming second(GO:0001702)
0.0 0.1 GO:0051152 positive regulation of smooth muscle cell differentiation(GO:0051152)
0.0 0.2 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.9 GO:0061178 regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061178)
0.0 0.4 GO:0022400 regulation of rhodopsin mediated signaling pathway(GO:0022400)
0.0 0.1 GO:0009256 10-formyltetrahydrofolate metabolic process(GO:0009256)
0.0 0.3 GO:0070987 error-free translesion synthesis(GO:0070987)
0.0 0.4 GO:0031424 keratinization(GO:0031424)
0.0 0.2 GO:0052695 cellular glucuronidation(GO:0052695)
0.0 0.1 GO:0006782 protoporphyrinogen IX biosynthetic process(GO:0006782)
0.0 0.4 GO:0045668 negative regulation of osteoblast differentiation(GO:0045668)
0.0 0.8 GO:0001895 retina homeostasis(GO:0001895)
0.0 0.2 GO:0007097 nuclear migration(GO:0007097)
0.0 1.2 GO:0002181 cytoplasmic translation(GO:0002181)
0.0 0.2 GO:0042832 carbohydrate mediated signaling(GO:0009756) defense response to protozoan(GO:0042832)
0.0 0.2 GO:0033617 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.0 0.3 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.1 GO:0043512 inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.7 4.7 GO:0097209 epidermal lamellar body(GO:0097209)
0.5 3.4 GO:0097179 protease inhibitor complex(GO:0097179)
0.4 1.3 GO:0005595 collagen type XII trimer(GO:0005595)
0.4 1.4 GO:0071020 post-spliceosomal complex(GO:0071020)
0.3 2.6 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
0.3 1.2 GO:0005889 hydrogen:potassium-exchanging ATPase complex(GO:0005889)
0.3 1.4 GO:0031905 early endosome lumen(GO:0031905)
0.2 0.6 GO:0000806 Y chromosome(GO:0000806)
0.2 2.1 GO:0005610 laminin-5 complex(GO:0005610)
0.2 3.2 GO:0042613 MHC class II protein complex(GO:0042613)
0.1 11.0 GO:0001533 cornified envelope(GO:0001533)
0.1 0.4 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.1 1.7 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.1 0.5 GO:0016939 kinesin II complex(GO:0016939)
0.1 2.0 GO:0031201 SNARE complex(GO:0031201)
0.1 0.4 GO:0005674 transcription factor TFIIF complex(GO:0005674)
0.1 2.0 GO:0097512 cardiac myofibril(GO:0097512)
0.1 2.5 GO:0030127 COPII vesicle coat(GO:0030127)
0.1 1.5 GO:0005687 U4 snRNP(GO:0005687)
0.1 0.6 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.1 2.8 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.1 0.8 GO:0061574 ASAP complex(GO:0061574)
0.1 0.4 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.1 1.2 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.1 0.3 GO:0072536 interleukin-23 receptor complex(GO:0072536)
0.1 0.5 GO:0070847 core mediator complex(GO:0070847)
0.1 0.6 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.1 0.2 GO:0098855 HCN channel complex(GO:0098855)
0.1 0.2 GO:0005602 complement component C1 complex(GO:0005602)
0.1 0.7 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.1 0.3 GO:1990425 ryanodine receptor complex(GO:1990425)
0.0 4.0 GO:0045095 keratin filament(GO:0045095)
0.0 0.5 GO:1990812 growth cone filopodium(GO:1990812)
0.0 0.2 GO:0032449 CBM complex(GO:0032449)
0.0 0.3 GO:0072557 IPAF inflammasome complex(GO:0072557)
0.0 0.2 GO:0031592 centrosomal corona(GO:0031592)
0.0 0.3 GO:0034274 Atg12-Atg5-Atg16 complex(GO:0034274)
0.0 0.6 GO:0097025 lateral loop(GO:0043219) MPP7-DLG1-LIN7 complex(GO:0097025)
0.0 0.9 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.5 GO:0045180 basal cortex(GO:0045180)
0.0 0.9 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.7 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 0.4 GO:0036157 outer dynein arm(GO:0036157)
0.0 0.3 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.0 0.9 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.3 GO:0005663 DNA replication factor C complex(GO:0005663)
0.0 0.8 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 1.2 GO:0071437 invadopodium(GO:0071437)
0.0 0.6 GO:0036038 MKS complex(GO:0036038)
0.0 0.2 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
0.0 0.4 GO:0005869 dynactin complex(GO:0005869)
0.0 0.5 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.1 GO:0033011 perinuclear theca(GO:0033011)
0.0 0.7 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.0 0.3 GO:0001520 outer dense fiber(GO:0001520)
0.0 0.2 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 2.4 GO:0031594 neuromuscular junction(GO:0031594)
0.0 0.5 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 0.4 GO:0017119 Golgi transport complex(GO:0017119)
0.0 0.1 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.0 2.7 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 1.4 GO:1990391 DNA repair complex(GO:1990391)
0.0 0.7 GO:0031105 septin complex(GO:0031105)
0.0 0.5 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.5 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.8 GO:0097228 sperm principal piece(GO:0097228)
0.0 0.2 GO:0001673 male germ cell nucleus(GO:0001673)
0.0 0.4 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 0.6 GO:0031258 lamellipodium membrane(GO:0031258)
0.0 0.3 GO:0070578 RISC-loading complex(GO:0070578)
0.0 0.2 GO:0016342 catenin complex(GO:0016342)
0.0 0.4 GO:0031094 platelet dense tubular network(GO:0031094)
0.0 0.3 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.3 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.0 0.2 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.0 1.8 GO:0035578 azurophil granule lumen(GO:0035578)
0.0 0.1 GO:0016013 syntrophin complex(GO:0016013)
0.0 0.2 GO:0042587 glycogen granule(GO:0042587)
0.0 0.4 GO:0071011 precatalytic spliceosome(GO:0071011)
0.0 0.1 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.0 0.1 GO:0036156 inner dynein arm(GO:0036156)
0.0 0.1 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.0 0.2 GO:0031089 platelet dense granule lumen(GO:0031089)
0.0 0.1 GO:0097013 phagocytic vesicle lumen(GO:0097013)
0.0 0.0 GO:0005833 hemoglobin complex(GO:0005833)
0.0 1.5 GO:0005796 Golgi lumen(GO:0005796)
0.0 0.2 GO:0000815 ESCRT III complex(GO:0000815)
0.0 0.1 GO:1990635 proximal dendrite(GO:1990635)
0.0 0.5 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.0 0.1 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.7 GO:0005150 interleukin-1, Type I receptor binding(GO:0005150)
0.4 1.5 GO:0047273 galactosylgalactosylglucosylceramide beta-D-acetylgalactosaminyltransferase activity(GO:0047273)
0.4 1.1 GO:0016503 pheromone receptor activity(GO:0016503)
0.3 2.1 GO:0070699 type II activin receptor binding(GO:0070699)
0.3 1.4 GO:0035651 AP-1 adaptor complex binding(GO:0035650) AP-3 adaptor complex binding(GO:0035651)
0.3 1.2 GO:0004917 interleukin-7 receptor activity(GO:0004917)
0.3 1.2 GO:0008900 hydrogen:potassium-exchanging ATPase activity(GO:0008900)
0.3 1.2 GO:0048030 disaccharide binding(GO:0048030)
0.3 1.4 GO:0000386 second spliceosomal transesterification activity(GO:0000386)
0.3 1.5 GO:0017060 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity(GO:0017060)
0.3 0.8 GO:0005152 interleukin-1 receptor antagonist activity(GO:0005152)
0.2 1.0 GO:0047751 3-oxo-5-alpha-steroid 4-dehydrogenase activity(GO:0003865) steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765) cholestenone 5-alpha-reductase activity(GO:0047751)
0.2 2.7 GO:0019534 toxin transporter activity(GO:0019534)
0.2 4.1 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.2 3.3 GO:0032395 MHC class II receptor activity(GO:0032395)
0.2 1.1 GO:0016316 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828)
0.2 0.8 GO:0010348 lithium:proton antiporter activity(GO:0010348)
0.2 2.4 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.2 0.5 GO:0016992 lipoate synthase activity(GO:0016992) radical SAM enzyme activity(GO:0070283)
0.2 1.2 GO:0004771 sterol esterase activity(GO:0004771)
0.2 5.3 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.2 1.1 GO:0047894 flavonol 3-sulfotransferase activity(GO:0047894) steroid sulfotransferase activity(GO:0050294)
0.2 1.4 GO:0070891 lipoteichoic acid binding(GO:0070891)
0.1 0.4 GO:0070538 oleic acid binding(GO:0070538)
0.1 0.4 GO:0016401 palmitoyl-CoA oxidase activity(GO:0016401)
0.1 3.3 GO:0050700 CARD domain binding(GO:0050700)
0.1 1.0 GO:0008241 peptidyl-dipeptidase activity(GO:0008241)
0.1 0.5 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.1 1.4 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.1 0.5 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.1 1.8 GO:0042608 T cell receptor binding(GO:0042608)
0.1 1.1 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.1 0.4 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.1 0.4 GO:1904492 Ac-Asp-Glu binding(GO:1904492) tetrahydrofolyl-poly(glutamate) polymer binding(GO:1904493)
0.1 1.5 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.1 0.3 GO:0033149 FFAT motif binding(GO:0033149)
0.1 0.7 GO:0070728 leucine binding(GO:0070728)
0.1 0.4 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.1 0.3 GO:0001160 transcription termination site sequence-specific DNA binding(GO:0001147) transcription termination site DNA binding(GO:0001160)
0.1 0.7 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.1 0.4 GO:0047888 fatty acid peroxidase activity(GO:0047888)
0.1 0.3 GO:0019961 interferon binding(GO:0019961)
0.1 0.8 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.1 0.3 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.1 1.4 GO:0015194 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.1 2.0 GO:0005212 structural constituent of eye lens(GO:0005212)
0.1 1.2 GO:0016018 cyclosporin A binding(GO:0016018)
0.1 2.5 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.1 2.4 GO:0004806 triglyceride lipase activity(GO:0004806)
0.1 0.3 GO:0004040 amidase activity(GO:0004040)
0.1 1.7 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.1 0.6 GO:0050816 phosphothreonine binding(GO:0050816)
0.1 10.4 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.1 2.5 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.1 0.3 GO:0042019 interleukin-23 binding(GO:0042019) interleukin-23 receptor activity(GO:0042020)
0.1 0.3 GO:0004530 deoxyribonuclease I activity(GO:0004530)
0.1 0.3 GO:0034875 oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875)
0.1 0.5 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095)
0.1 0.4 GO:0033857 diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.1 0.3 GO:0019776 Atg8 ligase activity(GO:0019776)
0.1 0.3 GO:0008267 poly-glutamine tract binding(GO:0008267)
0.1 0.2 GO:0008746 NAD(P)+ transhydrogenase activity(GO:0008746) oxidoreductase activity, acting on NAD(P)H, NAD(P) as acceptor(GO:0016652)
0.1 0.3 GO:0016402 pristanoyl-CoA oxidase activity(GO:0016402)
0.1 0.7 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.0 0.6 GO:0097016 L27 domain binding(GO:0097016)
0.0 0.4 GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)
0.0 0.3 GO:0009019 tRNA (guanine-N1-)-methyltransferase activity(GO:0009019)
0.0 0.5 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.0 0.3 GO:0008823 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.0 2.1 GO:0001972 retinoic acid binding(GO:0001972)
0.0 1.5 GO:0008329 signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187)
0.0 0.8 GO:0032052 bile acid binding(GO:0032052)
0.0 0.1 GO:0016749 5-aminolevulinate synthase activity(GO:0003870) N-succinyltransferase activity(GO:0016749)
0.0 0.3 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.0 0.1 GO:0004487 methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487)
0.0 0.7 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 3.7 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.0 0.6 GO:0043855 intracellular cyclic nucleotide activated cation channel activity(GO:0005221) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.0 2.0 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.2 GO:0004910 interleukin-1, Type II, blocking receptor activity(GO:0004910)
0.0 0.1 GO:0061752 telomeric repeat-containing RNA binding(GO:0061752)
0.0 0.1 GO:0004510 tryptophan 5-monooxygenase activity(GO:0004510)
0.0 0.4 GO:0004046 aminoacylase activity(GO:0004046)
0.0 0.2 GO:0018685 alkane 1-monooxygenase activity(GO:0018685)
0.0 1.2 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.0 3.1 GO:0033558 histone deacetylase activity(GO:0004407) protein deacetylase activity(GO:0033558)
0.0 1.3 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.8 GO:0001056 RNA polymerase III activity(GO:0001056)
0.0 0.2 GO:0001225 RNA polymerase II transcription coactivator binding(GO:0001225)
0.0 1.8 GO:0003785 actin monomer binding(GO:0003785)
0.0 1.1 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 1.7 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.0 0.6 GO:0000150 recombinase activity(GO:0000150)
0.0 1.6 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.2 GO:0031708 endothelin B receptor binding(GO:0031708)
0.0 0.3 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0 0.5 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.0 1.7 GO:0016303 1-phosphatidylinositol-3-kinase activity(GO:0016303)
0.0 0.3 GO:0033170 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0 0.6 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.0 0.9 GO:0000339 RNA cap binding(GO:0000339)
0.0 0.4 GO:0047134 protein-disulfide reductase activity(GO:0047134)
0.0 0.5 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.0 0.3 GO:0000268 peroxisome targeting sequence binding(GO:0000268)
0.0 0.9 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 0.2 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 0.3 GO:0003796 lysozyme activity(GO:0003796)
0.0 0.1 GO:0017098 sulfonylurea receptor binding(GO:0017098)
0.0 1.2 GO:0046966 thyroid hormone receptor binding(GO:0046966)
0.0 0.0 GO:0034604 pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604)
0.0 0.1 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0 1.1 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.4 GO:0015245 fatty acid transporter activity(GO:0015245)
0.0 0.1 GO:0004667 prostaglandin-D synthase activity(GO:0004667)
0.0 0.4 GO:0008199 ferric iron binding(GO:0008199)
0.0 0.1 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.0 0.2 GO:0048156 tau protein binding(GO:0048156)
0.0 0.1 GO:0052810 1-phosphatidylinositol-5-kinase activity(GO:0052810)
0.0 0.2 GO:0004024 alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
0.0 0.2 GO:0070840 dynein complex binding(GO:0070840)
0.0 0.1 GO:0035529 NADH pyrophosphatase activity(GO:0035529)
0.0 0.1 GO:0005166 neurotrophin p75 receptor binding(GO:0005166)
0.0 0.1 GO:1990190 peptide-glutamate-N-acetyltransferase activity(GO:1990190)
0.0 0.1 GO:0061665 SUMO ligase activity(GO:0061665)
0.0 0.6 GO:0042288 MHC class I protein binding(GO:0042288)
0.0 0.1 GO:0005353 fructose transmembrane transporter activity(GO:0005353)
0.0 0.3 GO:0045295 gamma-catenin binding(GO:0045295)
0.0 0.5 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.0 0.2 GO:0043422 protein kinase B binding(GO:0043422)
0.0 0.4 GO:0031005 filamin binding(GO:0031005)
0.0 0.5 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.1 GO:0015056 corticotrophin-releasing factor receptor activity(GO:0015056)
0.0 0.2 GO:0086007 voltage-gated calcium channel activity involved in cardiac muscle cell action potential(GO:0086007)
0.0 3.3 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 0.3 GO:0001223 transcription coactivator binding(GO:0001223)
0.0 0.3 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.1 GO:0030021 extracellular matrix structural constituent conferring compression resistance(GO:0030021) extracellular matrix constituent, lubricant activity(GO:0030197) structural constituent of tooth enamel(GO:0030345)
0.0 0.1 GO:0005314 high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.0 0.2 GO:0009374 biotin carboxylase activity(GO:0004075) biotin binding(GO:0009374)
0.0 0.0 GO:0008398 sterol 14-demethylase activity(GO:0008398)
0.0 0.2 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.2 GO:0039706 co-receptor binding(GO:0039706)
0.0 2.3 GO:0008201 heparin binding(GO:0008201)
0.0 1.3 GO:0008013 beta-catenin binding(GO:0008013)
0.0 0.2 GO:0030957 Tat protein binding(GO:0030957)
0.0 0.1 GO:0003747 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 7.2 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.1 2.1 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.1 6.1 SIG PIP3 SIGNALING IN B LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.1 2.2 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.1 2.4 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.1 2.5 PID ALK1 PATHWAY ALK1 signaling events
0.0 1.9 PID TRAIL PATHWAY TRAIL signaling pathway
0.0 0.3 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.0 2.9 PID IL1 PATHWAY IL1-mediated signaling events
0.0 3.0 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 10.6 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.0 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 1.0 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 5.6 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.4 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 0.9 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 1.0 PID PS1 PATHWAY Presenilin action in Notch and Wnt signaling
0.0 4.9 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.3 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0 1.6 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 0.3 PID MYC PATHWAY C-MYC pathway
0.0 0.2 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 0.3 PID FAS PATHWAY FAS (CD95) signaling pathway
0.0 0.9 PID FOXO PATHWAY FoxO family signaling
0.0 0.6 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 0.9 PID TELOMERASE PATHWAY Regulation of Telomerase

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.1 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.2 3.8 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.1 2.7 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.1 3.6 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.1 7.4 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.1 3.0 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.1 1.0 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.1 2.5 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.1 1.3 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.1 1.4 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.1 0.6 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.1 3.3 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 2.7 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 1.5 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.0 1.1 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 1.0 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 0.8 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 0.6 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 1.2 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 0.9 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.0 0.4 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 0.6 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 0.4 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.0 1.6 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 0.3 REACTOME MICRORNA MIRNA BIOGENESIS Genes involved in MicroRNA (miRNA) Biogenesis
0.0 0.6 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.3 REACTOME INFLAMMASOMES Genes involved in Inflammasomes
0.0 0.5 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 1.1 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 1.6 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 2.5 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0 0.3 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.0 0.5 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
0.0 0.2 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.0 2.4 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.3 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 1.0 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 1.9 REACTOME CELL JUNCTION ORGANIZATION Genes involved in Cell junction organization
0.0 0.6 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 0.2 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.5 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 0.5 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 0.2 REACTOME TAK1 ACTIVATES NFKB BY PHOSPHORYLATION AND ACTIVATION OF IKKS COMPLEX Genes involved in TAK1 activates NFkB by phosphorylation and activation of IKKs complex
0.0 0.5 REACTOME TGF BETA RECEPTOR SIGNALING ACTIVATES SMADS Genes involved in TGF-beta receptor signaling activates SMADs
0.0 0.3 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.0 1.0 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 1.1 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 0.2 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism