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SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for IRX5

Z-value: 0.47

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Transcription factors associated with IRX5

Gene Symbol Gene ID Gene Info
IRX5
ENSG00000176842.10 iroquois homeobox 5

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
IRX5hg19_v2_chr16_+_54964740_549647890.351.3e-01Click!

Activity profile of IRX5 motif

Sorted Z-values of IRX5 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr4_+_141264597 1.96 ENST00000338517.4
ENST00000394203.3
ENST00000506322.1
SCOC
short coiled-coil protein
chr13_+_97928395 0.97 ENST00000445661.2
MBNL2
muscleblind-like splicing regulator 2
chr10_-_115904361 0.72 ENST00000428953.1
ENST00000543782.1
C10orf118
chromosome 10 open reading frame 118
chr4_-_104119528 0.70 ENST00000380026.3
ENST00000503705.1
ENST00000265148.3
CENPE
centromere protein E, 312kDa
chr5_+_169011033 0.69 ENST00000513795.1
SPDL1
spindle apparatus coiled-coil protein 1
chr8_+_27631903 0.67 ENST00000305188.8
ESCO2
establishment of sister chromatid cohesion N-acetyltransferase 2
chr15_+_66585555 0.60 ENST00000319194.5
ENST00000525134.2
ENST00000441424.2
DIS3L
DIS3 mitotic control homolog (S. cerevisiae)-like
chr8_+_22225041 0.55 ENST00000289952.5
ENST00000524285.1
SLC39A14
solute carrier family 39 (zinc transporter), member 14
chr15_-_64665911 0.55 ENST00000606793.1
ENST00000561349.1
ENST00000560278.1
CTD-2116N17.1
Uncharacterized protein
chr1_-_197115818 0.54 ENST00000367409.4
ENST00000294732.7
ASPM
asp (abnormal spindle) homolog, microcephaly associated (Drosophila)
chr3_+_180586536 0.51 ENST00000465551.1
FXR1
fragile X mental retardation, autosomal homolog 1
chr12_-_100486668 0.50 ENST00000550544.1
ENST00000551980.1
ENST00000548045.1
ENST00000545232.2
ENST00000551973.1
UHRF1BP1L
UHRF1 binding protein 1-like
chr1_+_212475148 0.50 ENST00000537030.3
PPP2R5A
protein phosphatase 2, regulatory subunit B', alpha
chr7_-_55583740 0.49 ENST00000453256.1
VOPP1
vesicular, overexpressed in cancer, prosurvival protein 1
chr14_+_73563735 0.48 ENST00000532192.1
RBM25
RNA binding motif protein 25
chr4_+_169842707 0.48 ENST00000503290.1
PALLD
palladin, cytoskeletal associated protein
chr1_+_220267429 0.46 ENST00000366922.1
ENST00000302637.5
IARS2
isoleucyl-tRNA synthetase 2, mitochondrial
chr3_-_27498235 0.45 ENST00000295736.5
ENST00000428386.1
ENST00000428179.1
SLC4A7
solute carrier family 4, sodium bicarbonate cotransporter, member 7
chr3_-_124606502 0.44 ENST00000483168.1
ITGB5
integrin, beta 5
chr5_+_169010638 0.44 ENST00000265295.4
ENST00000506574.1
ENST00000515224.1
ENST00000508247.1
ENST00000513941.1
SPDL1
spindle apparatus coiled-coil protein 1
chr2_+_191792376 0.42 ENST00000409428.1
ENST00000409215.1
GLS
glutaminase
chr21_+_38792602 0.41 ENST00000398960.2
ENST00000398956.2
DYRK1A
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A
chr8_-_101962777 0.40 ENST00000395951.3
YWHAZ
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
chr18_+_22006646 0.39 ENST00000585067.1
ENST00000578221.1
IMPACT
impact RWD domain protein
chr11_+_61891445 0.39 ENST00000394818.3
ENST00000533896.1
ENST00000278849.4
INCENP
inner centromere protein antigens 135/155kDa
chr9_-_19065082 0.39 ENST00000415524.1
HAUS6
HAUS augmin-like complex, subunit 6
chr4_-_104119488 0.38 ENST00000514974.1
CENPE
centromere protein E, 312kDa
chr2_+_160590469 0.38 ENST00000409591.1
MARCH7
membrane-associated ring finger (C3HC4) 7, E3 ubiquitin protein ligase
chr2_+_113299990 0.37 ENST00000537335.1
ENST00000417433.2
POLR1B
polymerase (RNA) I polypeptide B, 128kDa
chr1_-_8763278 0.35 ENST00000468247.1
RERE
arginine-glutamic acid dipeptide (RE) repeats
chr5_+_179135246 0.35 ENST00000508787.1
CANX
calnexin
chr13_+_76362974 0.34 ENST00000497947.2
LMO7
LIM domain 7
chr3_-_52713729 0.33 ENST00000296302.7
ENST00000356770.4
ENST00000337303.4
ENST00000409057.1
ENST00000410007.1
ENST00000409114.3
ENST00000409767.1
ENST00000423351.1
PBRM1
polybromo 1
chr9_-_125667618 0.33 ENST00000423239.2
RC3H2
ring finger and CCCH-type domains 2
chrX_-_15353629 0.33 ENST00000333590.4
ENST00000428964.1
ENST00000542278.1
PIGA
phosphatidylinositol glycan anchor biosynthesis, class A
chr12_-_120315074 0.32 ENST00000261833.7
ENST00000392521.2
CIT
citron (rho-interacting, serine/threonine kinase 21)
chr7_+_116502527 0.32 ENST00000361183.3
CAPZA2
capping protein (actin filament) muscle Z-line, alpha 2
chr1_-_244006528 0.31 ENST00000336199.5
ENST00000263826.5
AKT3
v-akt murine thymoma viral oncogene homolog 3
chr4_-_143481822 0.30 ENST00000510812.1
INPP4B
inositol polyphosphate-4-phosphatase, type II, 105kDa
chr7_+_133615169 0.29 ENST00000541309.1
EXOC4
exocyst complex component 4
chr17_-_47723943 0.29 ENST00000510476.1
ENST00000503676.1
SPOP
speckle-type POZ protein
chr4_-_22444733 0.29 ENST00000508133.1
GPR125
G protein-coupled receptor 125
chr1_-_85156417 0.29 ENST00000422026.1
SSX2IP
synovial sarcoma, X breakpoint 2 interacting protein
chr1_-_115124257 0.29 ENST00000369541.3
BCAS2
breast carcinoma amplified sequence 2
chr17_-_6524159 0.28 ENST00000589033.1
KIAA0753
KIAA0753
chr16_-_58585513 0.28 ENST00000245138.4
ENST00000567285.1
CNOT1
CCR4-NOT transcription complex, subunit 1
chr3_+_111630451 0.28 ENST00000495180.1
PHLDB2
pleckstrin homology-like domain, family B, member 2
chr12_+_58335360 0.27 ENST00000300145.3
XRCC6BP1
XRCC6 binding protein 1
chr17_+_75447326 0.27 ENST00000591088.1
SEPT9
septin 9
chr5_-_156390230 0.26 ENST00000407087.3
ENST00000274532.2
TIMD4
T-cell immunoglobulin and mucin domain containing 4
chr13_+_24844857 0.26 ENST00000409126.1
ENST00000343003.6
SPATA13
spermatogenesis associated 13
chr16_+_19535133 0.26 ENST00000396212.2
ENST00000381396.5
CCP110
centriolar coiled coil protein 110kDa
chr1_+_87458692 0.26 ENST00000370548.2
ENST00000356813.4
RP5-1052I5.2
HS2ST1
Heparan sulfate 2-O-sulfotransferase 1
heparan sulfate 2-O-sulfotransferase 1
chrX_-_135962923 0.26 ENST00000565438.1
RBMX
RNA binding motif protein, X-linked
chr20_+_43990576 0.25 ENST00000372727.1
ENST00000414310.1
SYS1
SYS1 Golgi-localized integral membrane protein homolog (S. cerevisiae)
chr6_+_126221034 0.25 ENST00000433571.1
NCOA7
nuclear receptor coactivator 7
chrX_+_12809463 0.25 ENST00000380663.3
ENST00000380668.5
ENST00000398491.2
ENST00000489404.1
PRPS2
phosphoribosyl pyrophosphate synthetase 2
chr10_-_35379524 0.25 ENST00000374751.3
ENST00000374742.1
ENST00000602371.1
CUL2
cullin 2
chr2_+_38177575 0.25 ENST00000407257.1
ENST00000417700.2
ENST00000234195.3
ENST00000442857.1
RMDN2
regulator of microtubule dynamics 2
chr4_+_75480629 0.25 ENST00000380846.3
AREGB
amphiregulin B
chr4_+_41361616 0.25 ENST00000513024.1
LIMCH1
LIM and calponin homology domains 1
chr14_+_56127960 0.25 ENST00000553624.1
KTN1
kinectin 1 (kinesin receptor)
chr12_-_123728548 0.24 ENST00000545406.1
MPHOSPH9
M-phase phosphoprotein 9
chr10_+_90660832 0.24 ENST00000371924.1
STAMBPL1
STAM binding protein-like 1
chr14_-_68159152 0.24 ENST00000554035.1
RDH11
retinol dehydrogenase 11 (all-trans/9-cis/11-cis)
chr1_-_227505289 0.23 ENST00000366765.3
CDC42BPA
CDC42 binding protein kinase alpha (DMPK-like)
chr7_+_77469439 0.23 ENST00000450574.1
ENST00000416283.2
ENST00000248550.7
PHTF2
putative homeodomain transcription factor 2
chr3_+_158787041 0.23 ENST00000471575.1
ENST00000476809.1
ENST00000485419.1
IQCJ-SCHIP1
IQCJ-SCHIP1 readthrough
chr5_-_93447333 0.22 ENST00000395965.3
ENST00000505869.1
ENST00000509163.1
FAM172A
family with sequence similarity 172, member A
chr16_+_19535235 0.22 ENST00000565376.2
ENST00000396208.2
CCP110
centriolar coiled coil protein 110kDa
chr1_+_63989004 0.22 ENST00000371088.4
EFCAB7
EF-hand calcium binding domain 7
chr5_+_54455946 0.22 ENST00000503787.1
ENST00000296734.6
ENST00000515370.1
GPX8
glutathione peroxidase 8 (putative)
chr8_-_108510224 0.21 ENST00000517746.1
ENST00000297450.3
ANGPT1
angiopoietin 1
chr3_-_127541194 0.21 ENST00000453507.2
MGLL
monoglyceride lipase
chr14_+_56127989 0.21 ENST00000555573.1
KTN1
kinectin 1 (kinesin receptor)
chr10_-_91403625 0.21 ENST00000322191.6
ENST00000342512.3
ENST00000371774.2
PANK1
pantothenate kinase 1
chr11_+_57531292 0.21 ENST00000524579.1
CTNND1
catenin (cadherin-associated protein), delta 1
chr15_+_66585879 0.21 ENST00000319212.4
DIS3L
DIS3 mitotic control homolog (S. cerevisiae)-like
chr5_+_140566 0.20 ENST00000502646.1
PLEKHG4B
pleckstrin homology domain containing, family G (with RhoGef domain) member 4B
chr11_+_34999328 0.20 ENST00000526309.1
PDHX
pyruvate dehydrogenase complex, component X
chr15_+_81225699 0.20 ENST00000560027.1
KIAA1199
KIAA1199
chr4_+_75310851 0.20 ENST00000395748.3
ENST00000264487.2
AREG
amphiregulin
chr12_-_25102252 0.20 ENST00000261192.7
BCAT1
branched chain amino-acid transaminase 1, cytosolic
chrX_+_108779004 0.20 ENST00000218004.1
NXT2
nuclear transport factor 2-like export factor 2
chr14_+_51706886 0.20 ENST00000457354.2
TMX1
thioredoxin-related transmembrane protein 1
chr6_-_111804905 0.20 ENST00000358835.3
ENST00000435970.1
REV3L
REV3-like, polymerase (DNA directed), zeta, catalytic subunit
chr10_+_86184676 0.19 ENST00000543283.1
CCSER2
coiled-coil serine-rich protein 2
chr6_-_111804393 0.19 ENST00000368802.3
ENST00000368805.1
REV3L
REV3-like, polymerase (DNA directed), zeta, catalytic subunit
chr3_-_196987309 0.18 ENST00000453607.1
DLG1
discs, large homolog 1 (Drosophila)
chr15_+_49170083 0.18 ENST00000530028.2
EID1
EP300 interacting inhibitor of differentiation 1
chr1_-_149859466 0.18 ENST00000331128.3
HIST2H2AB
histone cluster 2, H2ab
chr4_+_159131630 0.18 ENST00000504569.1
ENST00000509278.1
ENST00000514558.1
ENST00000503200.1
TMEM144
transmembrane protein 144
chr18_+_22006580 0.17 ENST00000284202.4
IMPACT
impact RWD domain protein
chr13_+_24844819 0.17 ENST00000399949.2
SPATA13
spermatogenesis associated 13
chr1_-_23504176 0.17 ENST00000302291.4
LUZP1
leucine zipper protein 1
chr3_-_149470229 0.17 ENST00000473414.1
COMMD2
COMM domain containing 2
chr19_-_36909528 0.17 ENST00000392161.3
ENST00000392171.1
ZFP82
ZFP82 zinc finger protein
chr19_-_44952635 0.17 ENST00000592308.1
ENST00000588931.1
ENST00000291187.4
ZNF229
zinc finger protein 229
chr1_+_97188188 0.16 ENST00000541987.1
PTBP2
polypyrimidine tract binding protein 2
chr19_+_50691437 0.16 ENST00000598205.1
MYH14
myosin, heavy chain 14, non-muscle
chr1_-_85870177 0.16 ENST00000542148.1
DDAH1
dimethylarginine dimethylaminohydrolase 1
chr13_-_41768654 0.16 ENST00000379483.3
KBTBD7
kelch repeat and BTB (POZ) domain containing 7
chr12_-_76462713 0.16 ENST00000552056.1
NAP1L1
nucleosome assembly protein 1-like 1
chr4_+_26344754 0.15 ENST00000515573.1
RBPJ
recombination signal binding protein for immunoglobulin kappa J region
chr2_+_201173667 0.15 ENST00000409755.3
SPATS2L
spermatogenesis associated, serine-rich 2-like
chr13_+_50589390 0.15 ENST00000360473.4
ENST00000312942.1
KCNRG
potassium channel regulator
chr4_-_75695366 0.14 ENST00000512743.1
BTC
betacellulin
chr17_+_38673270 0.14 ENST00000578280.1
RP5-1028K7.2
RP5-1028K7.2
chr1_+_240408560 0.14 ENST00000441342.1
ENST00000545751.1
FMN2
formin 2
chr22_+_20877924 0.14 ENST00000445189.1
MED15
mediator complex subunit 15
chr11_+_110225855 0.14 ENST00000526605.1
ENST00000526703.1
RP11-347E10.1
RP11-347E10.1
chr16_+_19467772 0.14 ENST00000219821.5
ENST00000561503.1
ENST00000564959.1
TMC5
transmembrane channel-like 5
chr12_-_102224704 0.14 ENST00000299314.7
GNPTAB
N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits
chr4_+_144312659 0.14 ENST00000509992.1
GAB1
GRB2-associated binding protein 1
chr17_+_41561317 0.14 ENST00000540306.1
ENST00000262415.3
ENST00000605777.1
DHX8
DEAH (Asp-Glu-Ala-His) box polypeptide 8
chr2_-_32236002 0.13 ENST00000404530.1
MEMO1
mediator of cell motility 1
chr8_+_27947746 0.13 ENST00000521015.1
ENST00000521570.1
ELP3
elongator acetyltransferase complex subunit 3
chr7_-_111424506 0.13 ENST00000450156.1
ENST00000494651.2
DOCK4
dedicator of cytokinesis 4
chr22_+_18721427 0.13 ENST00000342888.3
AC008132.1
Uncharacterized protein
chr6_+_12008986 0.12 ENST00000491710.1
HIVEP1
human immunodeficiency virus type I enhancer binding protein 1
chr14_+_72052983 0.12 ENST00000358550.2
SIPA1L1
signal-induced proliferation-associated 1 like 1
chr4_+_159131596 0.12 ENST00000512481.1
TMEM144
transmembrane protein 144
chr18_+_33709834 0.11 ENST00000358232.6
ENST00000351393.6
ENST00000442325.2
ENST00000423854.2
ENST00000350494.6
ENST00000542824.1
ELP2
elongator acetyltransferase complex subunit 2
chr7_-_87856280 0.11 ENST00000490437.1
ENST00000431660.1
SRI
sorcin
chr2_-_242041607 0.11 ENST00000434791.1
ENST00000401626.2
ENST00000439144.1
ENST00000406593.1
ENST00000495694.1
ENST00000407095.3
ENST00000391980.2
MTERFD2
MTERF domain containing 2
chr9_+_96846740 0.11 ENST00000288976.3
PTPDC1
protein tyrosine phosphatase domain containing 1
chr5_+_67576109 0.11 ENST00000522084.1
PIK3R1
phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
chr15_-_56757329 0.11 ENST00000260453.3
MNS1
meiosis-specific nuclear structural 1
chr14_-_95624227 0.11 ENST00000526495.1
DICER1
dicer 1, ribonuclease type III
chr19_-_52531600 0.11 ENST00000356322.6
ENST00000270649.6
ZNF614
zinc finger protein 614
chr10_-_15130767 0.11 ENST00000356189.5
ACBD7
acyl-CoA binding domain containing 7
chr17_+_12859080 0.10 ENST00000583608.1
ARHGAP44
Rho GTPase activating protein 44
chr12_+_106751436 0.10 ENST00000228347.4
POLR3B
polymerase (RNA) III (DNA directed) polypeptide B
chr6_+_26204825 0.10 ENST00000360441.4
HIST1H4E
histone cluster 1, H4e
chr7_-_87856303 0.10 ENST00000394641.3
SRI
sorcin
chr3_+_186158169 0.10 ENST00000435548.1
ENST00000421006.1
RP11-78H24.1
RP11-78H24.1
chr4_-_103998439 0.10 ENST00000503230.1
ENST00000503818.1
SLC9B2
solute carrier family 9, subfamily B (NHA2, cation proton antiporter 2), member 2
chr8_-_67976509 0.10 ENST00000518747.1
COPS5
COP9 signalosome subunit 5
chr7_-_112430427 0.10 ENST00000449743.1
ENST00000441474.1
ENST00000454074.1
ENST00000447395.1
TMEM168
transmembrane protein 168
chr10_-_14050522 0.10 ENST00000342409.2
FRMD4A
FERM domain containing 4A
chr5_+_136070614 0.10 ENST00000502421.1
CTB-1I21.1
CTB-1I21.1
chr4_+_113739244 0.09 ENST00000503271.1
ENST00000503423.1
ENST00000506722.1
ANK2
ankyrin 2, neuronal
chr8_+_125463048 0.09 ENST00000328599.3
TRMT12
tRNA methyltransferase 12 homolog (S. cerevisiae)
chr3_-_72897545 0.09 ENST00000325599.8
SHQ1
SHQ1, H/ACA ribonucleoprotein assembly factor
chr1_-_145826450 0.09 ENST00000462900.2
GPR89A
G protein-coupled receptor 89A
chr18_-_69246167 0.09 ENST00000566582.1
RP11-510D19.1
RP11-510D19.1
chr7_+_871559 0.08 ENST00000421580.1
SUN1
Sad1 and UNC84 domain containing 1
chr8_+_101349823 0.08 ENST00000519566.1
KB-1991G8.1
KB-1991G8.1
chr4_+_189376725 0.08 ENST00000510832.1
ENST00000510005.1
ENST00000503458.1
LINC01060
long intergenic non-protein coding RNA 1060
chr19_-_50266580 0.08 ENST00000246801.3
TSKS
testis-specific serine kinase substrate
chr8_+_67976593 0.08 ENST00000262210.5
ENST00000412460.1
CSPP1
centrosome and spindle pole associated protein 1
chr15_+_21145765 0.08 ENST00000553416.1
CT60
cancer/testis antigen 60 (non-protein coding)
chr6_+_106988986 0.07 ENST00000457437.1
ENST00000535438.1
AIM1
absent in melanoma 1
chr2_-_127963343 0.07 ENST00000335247.7
CYP27C1
cytochrome P450, family 27, subfamily C, polypeptide 1
chr1_-_241683001 0.07 ENST00000366560.3
FH
fumarate hydratase
chr18_-_69246186 0.07 ENST00000568095.1
RP11-510D19.1
RP11-510D19.1
chr7_-_111424462 0.07 ENST00000437129.1
DOCK4
dedicator of cytokinesis 4
chr11_+_31531291 0.07 ENST00000350638.5
ENST00000379163.5
ENST00000395934.2
ELP4
elongator acetyltransferase complex subunit 4
chr1_+_53308398 0.07 ENST00000371528.1
ZYG11A
zyg-11 family member A, cell cycle regulator
chr12_+_32655110 0.07 ENST00000546442.1
ENST00000583694.1
FGD4
FYVE, RhoGEF and PH domain containing 4
chr2_-_40657397 0.06 ENST00000408028.2
ENST00000332839.4
ENST00000406391.2
ENST00000542024.1
ENST00000542756.1
ENST00000405901.3
SLC8A1
solute carrier family 8 (sodium/calcium exchanger), member 1
chr2_+_173686303 0.06 ENST00000397087.3
RAPGEF4
Rap guanine nucleotide exchange factor (GEF) 4
chr20_+_54933971 0.06 ENST00000371384.3
ENST00000437418.1
FAM210B
family with sequence similarity 210, member B
chr20_-_29896388 0.06 ENST00000400549.1
DEFB116
defensin, beta 116
chr18_-_44702668 0.06 ENST00000256433.3
IER3IP1
immediate early response 3 interacting protein 1
chr1_-_21377447 0.06 ENST00000374937.3
ENST00000264211.8
EIF4G3
eukaryotic translation initiation factor 4 gamma, 3
chr9_-_3489428 0.06 ENST00000451859.1
RFX3
regulatory factor X, 3 (influences HLA class II expression)
chr15_-_44116873 0.06 ENST00000267812.3
MFAP1
microfibrillar-associated protein 1
chr3_-_81792780 0.05 ENST00000489715.1
GBE1
glucan (1,4-alpha-), branching enzyme 1
chr17_-_7108436 0.05 ENST00000493294.1
DLG4
discs, large homolog 4 (Drosophila)
chr4_+_123653882 0.05 ENST00000433287.1
BBS12
Bardet-Biedl syndrome 12
chr6_-_138833630 0.05 ENST00000533765.1
NHSL1
NHS-like 1
chr3_-_3221358 0.05 ENST00000424814.1
ENST00000450014.1
ENST00000231948.4
ENST00000432408.2
CRBN
cereblon
chr11_+_114310237 0.05 ENST00000539119.1
REXO2
RNA exonuclease 2
chrX_+_47867194 0.05 ENST00000376940.3
SPACA5
sperm acrosome associated 5
chr10_-_51958906 0.05 ENST00000489640.1
ASAH2
N-acylsphingosine amidohydrolase (non-lysosomal ceramidase) 2
chrX_+_47990039 0.05 ENST00000304270.5
SPACA5B
sperm acrosome associated 5B
chr3_+_186383741 0.05 ENST00000232003.4
HRG
histidine-rich glycoprotein
chr14_+_35747825 0.05 ENST00000540871.1
PSMA6
proteasome (prosome, macropain) subunit, alpha type, 6
chr4_+_122722466 0.05 ENST00000243498.5
ENST00000379663.3
ENST00000509800.1
EXOSC9
exosome component 9
chr11_-_22647350 0.05 ENST00000327470.3
FANCF
Fanconi anemia, complementation group F
chr10_-_96829246 0.04 ENST00000371270.3
ENST00000535898.1
ENST00000539050.1
CYP2C8
cytochrome P450, family 2, subfamily C, polypeptide 8
chr12_+_32655048 0.04 ENST00000427716.2
ENST00000266482.3
FGD4
FYVE, RhoGEF and PH domain containing 4
chr1_+_196857144 0.04 ENST00000367416.2
ENST00000251424.4
ENST00000367418.2
CFHR4
complement factor H-related 4
chr1_+_158969752 0.04 ENST00000566111.1
IFI16
interferon, gamma-inducible protein 16
chr1_+_202317815 0.04 ENST00000608999.1
ENST00000336894.4
ENST00000480184.1
PPP1R12B
protein phosphatase 1, regulatory subunit 12B
chrX_-_83757399 0.04 ENST00000373177.2
ENST00000297977.5
ENST00000506585.2
ENST00000449553.2
HDX
highly divergent homeobox
chr4_+_113558612 0.04 ENST00000505034.1
ENST00000324052.6
LARP7
La ribonucleoprotein domain family, member 7
chr1_+_53480598 0.04 ENST00000430330.2
ENST00000408941.3
ENST00000478274.2
ENST00000484100.1
ENST00000435345.2
ENST00000488965.1
SCP2
sterol carrier protein 2
chr18_-_32924372 0.04 ENST00000261332.6
ENST00000399061.3
ZNF24
zinc finger protein 24
chr11_-_6790286 0.04 ENST00000338569.2
OR2AG2
olfactory receptor, family 2, subfamily AG, member 2
chr16_+_56969284 0.04 ENST00000568358.1
HERPUD1
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
chr14_+_39944025 0.03 ENST00000554328.1
ENST00000556620.1
ENST00000557197.1
RP11-111A21.1
RP11-111A21.1
chr10_-_18944123 0.03 ENST00000606425.1
RP11-139J15.7
Uncharacterized protein
chr9_-_37465396 0.03 ENST00000307750.4
ZBTB5
zinc finger and BTB domain containing 5
chr17_+_14277419 0.03 ENST00000436469.1
AC022816.2
AC022816.2
chrX_-_138790348 0.03 ENST00000414978.1
ENST00000519895.1
MCF2
MCF.2 cell line derived transforming sequence
chr5_+_96079240 0.03 ENST00000515663.1
CAST
calpastatin
chr3_+_12392971 0.03 ENST00000287820.6
PPARG
peroxisome proliferator-activated receptor gamma
chr17_-_18430160 0.03 ENST00000392176.3
FAM106A
family with sequence similarity 106, member A

Network of associatons between targets according to the STRING database.

First level regulatory network of IRX5

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0071264 regulation of eIF2 alpha phosphorylation by amino acid starvation(GO:0060733) regulation of translational initiation in response to starvation(GO:0071262) positive regulation of translational initiation in response to starvation(GO:0071264)
0.2 0.5 GO:0009786 regulation of asymmetric cell division(GO:0009786)
0.2 1.1 GO:0007079 mitotic chromosome movement towards spindle pole(GO:0007079)
0.1 0.5 GO:0032053 ciliary basal body organization(GO:0032053)
0.1 0.5 GO:0006428 isoleucyl-tRNA aminoacylation(GO:0006428)
0.1 2.0 GO:0061635 regulation of protein complex stability(GO:0061635)
0.1 0.7 GO:0034421 post-translational protein acetylation(GO:0034421)
0.1 0.5 GO:0090219 negative regulation of lipid kinase activity(GO:0090219)
0.1 0.4 GO:0006543 glutamine catabolic process(GO:0006543)
0.1 1.1 GO:0034501 protein localization to kinetochore(GO:0034501)
0.1 0.2 GO:0036367 adaptation of rhodopsin mediated signaling(GO:0016062) light adaption(GO:0036367)
0.1 0.3 GO:0021691 cerebellar Purkinje cell layer maturation(GO:0021691)
0.1 0.2 GO:0021503 neural fold bending(GO:0021503)
0.1 0.3 GO:0046391 5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
0.0 0.1 GO:0051758 homologous chromosome movement towards spindle pole involved in homologous chromosome segregation(GO:0051758)
0.0 0.1 GO:0016256 N-glycan processing to lysosome(GO:0016256)
0.0 0.3 GO:2000676 positive regulation of type B pancreatic cell apoptotic process(GO:2000676)
0.0 0.3 GO:0061470 T follicular helper cell differentiation(GO:0061470)
0.0 0.1 GO:0032290 peripheral nervous system myelin formation(GO:0032290)
0.0 0.8 GO:0016075 rRNA catabolic process(GO:0016075)
0.0 0.2 GO:0009099 branched-chain amino acid biosynthetic process(GO:0009082) leucine biosynthetic process(GO:0009098) valine biosynthetic process(GO:0009099)
0.0 0.4 GO:0007000 nucleolus organization(GO:0007000)
0.0 0.2 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.0 2.1 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 0.6 GO:1903874 ferrous iron transport(GO:0015684) ferrous iron transmembrane transport(GO:1903874)
0.0 0.2 GO:0002740 negative regulation of cytokine secretion involved in immune response(GO:0002740) Tie signaling pathway(GO:0048014)
0.0 0.2 GO:1904694 negative regulation of vascular smooth muscle contraction(GO:1904694)
0.0 0.3 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.0 0.1 GO:0006106 fumarate metabolic process(GO:0006106)
0.0 0.4 GO:0090168 Golgi reassembly(GO:0090168)
0.0 0.1 GO:0090071 negative regulation of ribosome biogenesis(GO:0090071)
0.0 0.3 GO:0048341 paraxial mesoderm formation(GO:0048341)
0.0 0.2 GO:0061732 mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
0.0 0.2 GO:0042695 thelarche(GO:0042695) mammary gland branching involved in thelarche(GO:0060744)
0.0 0.2 GO:1901297 positive regulation of ephrin receptor signaling pathway(GO:1901189) positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068)
0.0 0.2 GO:1903764 regulation of potassium ion export across plasma membrane(GO:1903764)
0.0 0.5 GO:0003334 keratinocyte development(GO:0003334)
0.0 0.2 GO:0055118 negative regulation of heart rate(GO:0010459) negative regulation of cardiac muscle contraction(GO:0055118)
0.0 0.1 GO:0098886 modification of dendritic spine(GO:0098886)
0.0 0.3 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.0 0.0 GO:2001027 negative regulation of endothelial cell chemotaxis(GO:2001027)
0.0 0.3 GO:0045793 positive regulation of cell size(GO:0045793)
0.0 0.3 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.0 0.4 GO:0002643 regulation of tolerance induction(GO:0002643)
0.0 0.5 GO:2000637 positive regulation of gene silencing by miRNA(GO:2000637)
0.0 0.4 GO:0090136 epithelial cell-cell adhesion(GO:0090136)
0.0 0.3 GO:0035020 regulation of Rac protein signal transduction(GO:0035020)
0.0 0.5 GO:0060117 auditory receptor cell development(GO:0060117)
0.0 0.3 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.0 0.1 GO:0002071 glandular epithelial cell maturation(GO:0002071) type B pancreatic cell maturation(GO:0072560)
0.0 0.1 GO:2001206 positive regulation of osteoclast development(GO:2001206)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.2 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.1 0.4 GO:0034684 integrin alphav-beta5 complex(GO:0034684)
0.1 0.4 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.1 0.3 GO:0002189 ribose phosphate diphosphokinase complex(GO:0002189)
0.0 0.5 GO:0072687 meiotic spindle(GO:0072687)
0.0 0.3 GO:0044530 supraspliceosomal complex(GO:0044530)
0.0 0.8 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
0.0 0.4 GO:0000801 central element(GO:0000801)
0.0 0.7 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.0 0.2 GO:0030891 VCB complex(GO:0030891)
0.0 0.3 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.0 0.4 GO:0070652 HAUS complex(GO:0070652)
0.0 0.2 GO:0097513 myosin II filament(GO:0097513)
0.0 0.3 GO:0032584 growth cone membrane(GO:0032584)
0.0 0.2 GO:0044326 dendritic spine neck(GO:0044326)
0.0 0.3 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 0.3 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.0 0.3 GO:0044233 ER-mitochondrion membrane contact site(GO:0044233)
0.0 0.2 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.0 0.4 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 0.2 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0 0.3 GO:0045180 basal cortex(GO:0045180)
0.0 0.6 GO:0034451 centriolar satellite(GO:0034451)
0.0 0.2 GO:0043219 lateral loop(GO:0043219)
0.0 0.3 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 1.1 GO:0005844 polysome(GO:0005844)
0.0 0.1 GO:1990578 perinuclear endoplasmic reticulum membrane(GO:1990578)
0.0 0.5 GO:0000159 protein phosphatase type 2A complex(GO:0000159)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.2 GO:0043515 kinetochore binding(GO:0043515)
0.1 0.5 GO:0004822 isoleucine-tRNA ligase activity(GO:0004822)
0.1 0.7 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.1 0.3 GO:0008267 poly-glutamine tract binding(GO:0008267)
0.1 0.2 GO:0035034 histone acetyltransferase regulator activity(GO:0035034)
0.1 0.4 GO:0004359 glutaminase activity(GO:0004359)
0.0 0.3 GO:0016316 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828)
0.0 0.6 GO:0015093 ferrous iron transmembrane transporter activity(GO:0015093)
0.0 0.5 GO:0033592 RNA strand annealing activity(GO:0033592)
0.0 0.1 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.0 0.2 GO:0052656 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.0 0.2 GO:0004594 pantothenate kinase activity(GO:0004594)
0.0 0.3 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.0 0.3 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0 0.1 GO:0004530 deoxyribonuclease I activity(GO:0004530)
0.0 0.2 GO:0004738 pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604)
0.0 0.1 GO:0010348 lithium:proton antiporter activity(GO:0010348)
0.0 0.2 GO:0016403 dimethylargininase activity(GO:0016403)
0.0 0.1 GO:0010484 H3 histone acetyltransferase activity(GO:0010484)
0.0 1.2 GO:0000175 3'-5'-exoribonuclease activity(GO:0000175)
0.0 0.2 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 0.5 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.4 GO:0001054 RNA polymerase I activity(GO:0001054)
0.0 0.5 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 0.1 GO:0005502 11-cis retinal binding(GO:0005502) all-trans retinal binding(GO:0005503)
0.0 0.2 GO:0097016 L27 domain binding(GO:0097016)
0.0 0.1 GO:0031812 G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
0.0 0.4 GO:0008408 3'-5' exonuclease activity(GO:0008408)
0.0 0.2 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 0.0 GO:0070538 oleic acid binding(GO:0070538)
0.0 0.2 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.3 GO:0048156 tau protein binding(GO:0048156)
0.0 0.3 GO:0034185 apolipoprotein binding(GO:0034185)
0.0 0.3 GO:0034483 heparan sulfate sulfotransferase activity(GO:0034483)
0.0 0.1 GO:0001056 RNA polymerase III activity(GO:0001056)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.5 PID PLK1 PATHWAY PLK1 signaling events
0.0 0.5 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.0 0.4 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 0.3 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.5 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 0.5 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 0.3 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 0.4 REACTOME DESTABILIZATION OF MRNA BY KSRP Genes involved in Destabilization of mRNA by KSRP
0.0 0.4 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.2 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.4 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1