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SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for ISX

Z-value: 0.60

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Transcription factors associated with ISX

Gene Symbol Gene ID Gene Info
ISX
ENSG00000175329.8 intestine specific homeobox

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ISXhg19_v2_chr22_+_35462129_35462156-0.302.0e-01Click!

Activity profile of ISX motif

Sorted Z-values of ISX motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr16_-_55866997 1.88 ENST00000360526.3
ENST00000361503.4
CES1
carboxylesterase 1
chr17_-_43045439 1.71 ENST00000253407.3
C1QL1
complement component 1, q subcomponent-like 1
chr2_-_228244013 1.70 ENST00000304568.3
TM4SF20
transmembrane 4 L six family member 20
chr14_-_94789663 1.17 ENST00000557225.1
ENST00000341584.3
SERPINA6
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6
chr12_+_104680659 1.11 ENST00000526691.1
ENST00000531691.1
ENST00000388854.3
ENST00000354940.6
ENST00000526390.1
ENST00000531689.1
TXNRD1
thioredoxin reductase 1
chr7_-_86849836 1.09 ENST00000455575.1
TMEM243
transmembrane protein 243, mitochondrial
chr3_-_149095652 1.00 ENST00000305366.3
TM4SF1
transmembrane 4 L six family member 1
chr6_-_85474219 0.99 ENST00000369663.5
TBX18
T-box 18
chr16_-_55867146 0.95 ENST00000422046.2
CES1
carboxylesterase 1
chr19_+_12902289 0.93 ENST00000302754.4
JUNB
jun B proto-oncogene
chr12_+_52695617 0.91 ENST00000293525.5
KRT86
keratin 86
chr7_-_86849883 0.89 ENST00000433078.1
TMEM243
transmembrane protein 243, mitochondrial
chr4_-_141348789 0.88 ENST00000414773.1
CLGN
calmegin
chr12_+_104680793 0.88 ENST00000529546.1
ENST00000529751.1
ENST00000540716.1
ENST00000528079.2
ENST00000526580.1
TXNRD1
thioredoxin reductase 1
chr1_-_197115818 0.87 ENST00000367409.4
ENST00000294732.7
ASPM
asp (abnormal spindle) homolog, microcephaly associated (Drosophila)
chr20_+_44441271 0.77 ENST00000335046.3
ENST00000243893.6
UBE2C
ubiquitin-conjugating enzyme E2C
chr4_-_141348999 0.73 ENST00000325617.5
CLGN
calmegin
chr15_-_75199213 0.73 ENST00000562698.1
FAM219B
family with sequence similarity 219, member B
chr11_-_124981475 0.72 ENST00000532156.1
ENST00000532407.1
ENST00000279968.4
ENST00000527766.1
ENST00000529583.1
ENST00000524373.1
ENST00000527271.1
ENST00000526175.1
ENST00000529609.1
ENST00000533273.1
ENST00000531909.1
ENST00000529530.1
TMEM218
transmembrane protein 218
chr10_-_99205607 0.72 ENST00000477692.2
ENST00000485122.2
ENST00000370886.5
ENST00000370885.4
ENST00000370902.3
ENST00000370884.5
EXOSC1
exosome component 1
chr17_-_18266797 0.72 ENST00000316694.3
ENST00000539052.1
SHMT1
serine hydroxymethyltransferase 1 (soluble)
chr6_-_30080863 0.69 ENST00000540829.1
TRIM31
tripartite motif containing 31
chr6_-_30080876 0.69 ENST00000376734.3
TRIM31
tripartite motif containing 31
chr11_-_63381925 0.64 ENST00000415826.1
PLA2G16
phospholipase A2, group XVI
chr17_-_18266818 0.64 ENST00000583780.1
SHMT1
serine hydroxymethyltransferase 1 (soluble)
chr20_-_50419055 0.64 ENST00000217086.4
SALL4
spalt-like transcription factor 4
chr9_-_4666421 0.62 ENST00000381895.5
SPATA6L
spermatogenesis associated 6-like
chr17_+_46970134 0.62 ENST00000503641.1
ENST00000514808.1
ATP5G1
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C1 (subunit 9)
chr12_+_70574088 0.62 ENST00000552324.1
RP11-320P7.2
RP11-320P7.2
chr17_-_18266660 0.62 ENST00000582653.1
ENST00000352886.6
SHMT1
serine hydroxymethyltransferase 1 (soluble)
chr11_-_63381823 0.61 ENST00000323646.5
PLA2G16
phospholipase A2, group XVI
chr17_-_18266765 0.60 ENST00000354098.3
SHMT1
serine hydroxymethyltransferase 1 (soluble)
chr20_+_44441215 0.59 ENST00000356455.4
ENST00000405520.1
UBE2C
ubiquitin-conjugating enzyme E2C
chr19_-_46285736 0.58 ENST00000291270.4
ENST00000447742.2
ENST00000354227.5
DMPK
dystrophia myotonica-protein kinase
chr6_+_127898312 0.58 ENST00000329722.7
C6orf58
chromosome 6 open reading frame 58
chr16_-_31106211 0.57 ENST00000532364.1
ENST00000529564.1
ENST00000319788.7
ENST00000354895.4
ENST00000394975.2
RP11-196G11.1
VKORC1
Uncharacterized protein
vitamin K epoxide reductase complex, subunit 1
chr4_-_89442940 0.56 ENST00000527353.1
PIGY
phosphatidylinositol glycan anchor biosynthesis, class Y
chr17_-_74733404 0.55 ENST00000508921.3
ENST00000583836.1
ENST00000358156.6
ENST00000392485.2
ENST00000359995.5
SRSF2
serine/arginine-rich splicing factor 2
chr17_+_42785976 0.54 ENST00000393547.2
ENST00000398338.3
DBF4B
DBF4 homolog B (S. cerevisiae)
chr10_+_91461337 0.53 ENST00000260753.4
ENST00000416354.1
ENST00000394289.2
ENST00000371728.3
KIF20B
kinesin family member 20B
chr7_+_148982396 0.53 ENST00000418158.2
ZNF783
zinc finger family member 783
chr6_+_30687978 0.52 ENST00000327892.8
ENST00000435534.1
TUBB
tubulin, beta class I
chr20_+_42544782 0.52 ENST00000423191.2
ENST00000372999.1
TOX2
TOX high mobility group box family member 2
chr6_+_3259148 0.52 ENST00000419065.2
ENST00000473000.2
ENST00000451246.2
ENST00000454610.2
PSMG4
proteasome (prosome, macropain) assembly chaperone 4
chr14_-_104181771 0.52 ENST00000554913.1
ENST00000554974.1
ENST00000553361.1
ENST00000555055.1
ENST00000555964.1
ENST00000556682.1
ENST00000445556.1
ENST00000553332.1
ENST00000352127.7
XRCC3
X-ray repair complementing defective repair in Chinese hamster cells 3
chr5_+_174151536 0.52 ENST00000239243.6
ENST00000507785.1
MSX2
msh homeobox 2
chr20_+_24449821 0.51 ENST00000376862.3
SYNDIG1
synapse differentiation inducing 1
chr19_-_3557570 0.51 ENST00000355415.2
MFSD12
major facilitator superfamily domain containing 12
chr17_+_78965624 0.51 ENST00000325167.5
CHMP6
charged multivesicular body protein 6
chr17_-_38821373 0.50 ENST00000394052.3
KRT222
keratin 222
chr5_-_177580855 0.49 ENST00000514354.1
ENST00000511078.1
NHP2
NHP2 ribonucleoprotein
chr19_-_51071302 0.49 ENST00000389201.3
ENST00000600381.1
LRRC4B
leucine rich repeat containing 4B
chr6_+_31126291 0.48 ENST00000376257.3
ENST00000376255.4
TCF19
transcription factor 19
chr1_-_159832438 0.48 ENST00000368100.1
VSIG8
V-set and immunoglobulin domain containing 8
chr1_+_206138457 0.46 ENST00000367128.3
ENST00000431655.2
FAM72A
family with sequence similarity 72, member A
chr19_-_46285646 0.46 ENST00000458663.2
DMPK
dystrophia myotonica-protein kinase
chr17_+_42786051 0.46 ENST00000315005.3
DBF4B
DBF4 homolog B (S. cerevisiae)
chr22_-_24316648 0.45 ENST00000403754.3
ENST00000430101.2
ENST00000398344.4
DDT
D-dopachrome tautomerase
chr10_+_91461413 0.44 ENST00000447580.1
KIF20B
kinesin family member 20B
chr5_-_177580777 0.44 ENST00000314397.4
NHP2
NHP2 ribonucleoprotein
chr10_-_114206649 0.44 ENST00000369404.3
ENST00000369405.3
ZDHHC6
zinc finger, DHHC-type containing 6
chr19_-_40931891 0.42 ENST00000357949.4
SERTAD1
SERTA domain containing 1
chrX_+_77154935 0.42 ENST00000481445.1
COX7B
cytochrome c oxidase subunit VIIb
chr1_+_120839005 0.42 ENST00000369390.3
ENST00000452190.1
FAM72B
family with sequence similarity 72, member B
chrX_-_47509994 0.41 ENST00000343894.4
ELK1
ELK1, member of ETS oncogene family
chr16_+_3333443 0.40 ENST00000572748.1
ENST00000573578.1
ENST00000574253.1
ZNF263
zinc finger protein 263
chr20_+_44441304 0.37 ENST00000352551.5
UBE2C
ubiquitin-conjugating enzyme E2C
chr17_+_73452545 0.37 ENST00000314256.7
KIAA0195
KIAA0195
chr16_+_12059091 0.37 ENST00000562385.1
TNFRSF17
tumor necrosis factor receptor superfamily, member 17
chr20_-_50418972 0.37 ENST00000395997.3
SALL4
spalt-like transcription factor 4
chr9_+_130159433 0.37 ENST00000451404.1
SLC2A8
solute carrier family 2 (facilitated glucose transporter), member 8
chr16_-_31105870 0.36 ENST00000394971.3
VKORC1
vitamin K epoxide reductase complex, subunit 1
chr1_-_143913143 0.36 ENST00000400889.1
FAM72D
family with sequence similarity 72, member D
chr4_-_174255536 0.36 ENST00000446922.2
HMGB2
high mobility group box 2
chr4_-_141348763 0.36 ENST00000509477.1
CLGN
calmegin
chr6_+_36562132 0.35 ENST00000373715.6
ENST00000339436.7
SRSF3
serine/arginine-rich splicing factor 3
chrX_+_108779004 0.35 ENST00000218004.1
NXT2
nuclear transport factor 2-like export factor 2
chr9_+_34646624 0.34 ENST00000450095.2
ENST00000556278.1
GALT
GALT
galactose-1-phosphate uridylyltransferase
Uncharacterized protein
chr17_-_7307358 0.34 ENST00000576017.1
ENST00000302422.3
ENST00000535512.1
TMEM256
TMEM256-PLSCR3
transmembrane protein 256
TMEM256-PLSCR3 readthrough (NMD candidate)
chr12_+_7013897 0.34 ENST00000007969.8
ENST00000323702.5
LRRC23
leucine rich repeat containing 23
chr5_-_177580933 0.34 ENST00000274606.3
NHP2
NHP2 ribonucleoprotein
chr12_+_7014064 0.33 ENST00000443597.2
LRRC23
leucine rich repeat containing 23
chr16_-_31106048 0.33 ENST00000300851.6
VKORC1
vitamin K epoxide reductase complex, subunit 1
chr16_+_2479390 0.33 ENST00000397066.4
CCNF
cyclin F
chr22_+_24309089 0.33 ENST00000215770.5
DDTL
D-dopachrome tautomerase-like
chr15_+_80351910 0.32 ENST00000261749.6
ENST00000561060.1
ZFAND6
zinc finger, AN1-type domain 6
chr9_+_34646651 0.32 ENST00000378842.3
GALT
galactose-1-phosphate uridylyltransferase
chr1_-_21620877 0.32 ENST00000527991.1
ECE1
endothelin converting enzyme 1
chr16_+_89160217 0.32 ENST00000317447.4
ENST00000537290.1
ACSF3
acyl-CoA synthetase family member 3
chr9_+_99212403 0.32 ENST00000375251.3
ENST00000375249.4
HABP4
hyaluronan binding protein 4
chr22_+_29138013 0.32 ENST00000216027.3
ENST00000398941.2
HSCB
HscB mitochondrial iron-sulfur cluster co-chaperone
chr1_+_28261492 0.32 ENST00000373894.3
SMPDL3B
sphingomyelin phosphodiesterase, acid-like 3B
chr14_-_81425828 0.31 ENST00000555529.1
ENST00000556042.1
ENST00000556981.1
CEP128
centrosomal protein 128kDa
chr4_+_110736659 0.31 ENST00000394631.3
ENST00000226796.6
GAR1
GAR1 ribonucleoprotein
chr17_-_48785216 0.31 ENST00000285243.6
ANKRD40
ankyrin repeat domain 40
chr20_-_50418947 0.31 ENST00000371539.3
SALL4
spalt-like transcription factor 4
chrX_+_77166172 0.31 ENST00000343533.5
ENST00000350425.4
ENST00000341514.6
ATP7A
ATPase, Cu++ transporting, alpha polypeptide
chr17_+_73452695 0.30 ENST00000582186.1
ENST00000582455.1
ENST00000581252.1
ENST00000579208.1
KIAA0195
KIAA0195
chr4_-_174255400 0.30 ENST00000506267.1
HMGB2
high mobility group box 2
chrY_+_14813160 0.30 ENST00000338981.3
USP9Y
ubiquitin specific peptidase 9, Y-linked
chr3_-_129147432 0.30 ENST00000503957.1
ENST00000505956.1
ENST00000326085.3
EFCAB12
EF-hand calcium binding domain 12
chr2_-_242089677 0.29 ENST00000405260.1
PASK
PAS domain containing serine/threonine kinase
chr5_+_140557371 0.29 ENST00000239444.2
PCDHB8
protocadherin beta 8
chr19_-_10227503 0.29 ENST00000593054.1
EIF3G
eukaryotic translation initiation factor 3, subunit G
chr7_+_150929550 0.29 ENST00000482173.1
ENST00000495645.1
ENST00000035307.2
CHPF2
chondroitin polymerizing factor 2
chr12_-_10978957 0.28 ENST00000240619.2
TAS2R10
taste receptor, type 2, member 10
chr17_+_40440481 0.28 ENST00000590726.2
ENST00000452307.2
ENST00000444283.1
ENST00000588868.1
STAT5A
signal transducer and activator of transcription 5A
chr17_+_59489112 0.28 ENST00000335108.2
C17orf82
chromosome 17 open reading frame 82
chr11_+_33061543 0.27 ENST00000432887.1
ENST00000528898.1
ENST00000531632.2
TCP11L1
t-complex 11, testis-specific-like 1
chr9_-_75488984 0.27 ENST00000423171.1
ENST00000449235.1
ENST00000453787.1
RP11-151D14.1
RP11-151D14.1
chr11_+_100862811 0.27 ENST00000303130.2
TMEM133
transmembrane protein 133
chr12_+_16500037 0.26 ENST00000536371.1
ENST00000010404.2
MGST1
microsomal glutathione S-transferase 1
chr16_+_3070313 0.26 ENST00000326577.4
TNFRSF12A
tumor necrosis factor receptor superfamily, member 12A
chr22_-_28490123 0.25 ENST00000442232.1
TTC28
tetratricopeptide repeat domain 28
chr12_-_57039739 0.24 ENST00000552959.1
ENST00000551020.1
ENST00000553007.2
ENST00000552919.1
ENST00000552104.1
ENST00000262030.3
ATP5B
ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide
chr14_+_39944025 0.23 ENST00000554328.1
ENST00000556620.1
ENST00000557197.1
RP11-111A21.1
RP11-111A21.1
chr1_-_190446759 0.23 ENST00000367462.3
BRINP3
bone morphogenetic protein/retinoic acid inducible neural-specific 3
chr2_+_172778952 0.23 ENST00000392584.1
ENST00000264108.4
HAT1
histone acetyltransferase 1
chr10_-_99447024 0.23 ENST00000370626.3
AVPI1
arginine vasopressin-induced 1
chr4_+_66536248 0.23 ENST00000514260.1
ENST00000507117.1
RP11-807H7.1
RP11-807H7.1
chr3_+_111393501 0.23 ENST00000393934.3
PLCXD2
phosphatidylinositol-specific phospholipase C, X domain containing 2
chr10_+_124914285 0.22 ENST00000407911.2
BUB3
BUB3 mitotic checkpoint protein
chr10_+_124913793 0.22 ENST00000368865.4
ENST00000538238.1
ENST00000368859.2
BUB3
BUB3 mitotic checkpoint protein
chrX_-_47509887 0.22 ENST00000247161.3
ENST00000592066.1
ENST00000376983.3
ELK1
ELK1, member of ETS oncogene family
chr1_+_28261621 0.22 ENST00000549094.1
SMPDL3B
sphingomyelin phosphodiesterase, acid-like 3B
chr17_-_57229155 0.22 ENST00000584089.1
SKA2
spindle and kinetochore associated complex subunit 2
chr8_+_9953214 0.21 ENST00000382490.5
MSRA
methionine sulfoxide reductase A
chr15_+_48413169 0.21 ENST00000341459.3
ENST00000482911.2
SLC24A5
solute carrier family 24 (sodium/potassium/calcium exchanger), member 5
chr8_+_9953061 0.21 ENST00000522907.1
ENST00000528246.1
MSRA
methionine sulfoxide reductase A
chr10_+_124913930 0.21 ENST00000368858.5
BUB3
BUB3 mitotic checkpoint protein
chr6_-_33385854 0.21 ENST00000488478.1
CUTA
cutA divalent cation tolerance homolog (E. coli)
chr6_-_119256279 0.21 ENST00000316068.3
MCM9
minichromosome maintenance complex component 9
chr17_+_79650962 0.21 ENST00000329138.4
HGS
hepatocyte growth factor-regulated tyrosine kinase substrate
chr5_+_159848807 0.21 ENST00000352433.5
PTTG1
pituitary tumor-transforming 1
chr22_+_17956618 0.21 ENST00000262608.8
CECR2
cat eye syndrome chromosome region, candidate 2
chr4_-_138453606 0.21 ENST00000412923.2
ENST00000344876.4
ENST00000507846.1
ENST00000510305.1
PCDH18
protocadherin 18
chr1_+_62902308 0.20 ENST00000339950.4
USP1
ubiquitin specific peptidase 1
chr5_+_177631497 0.20 ENST00000358344.3
HNRNPAB
heterogeneous nuclear ribonucleoprotein A/B
chr17_-_27418537 0.20 ENST00000408971.2
TIAF1
TGFB1-induced anti-apoptotic factor 1
chr1_+_32666188 0.20 ENST00000421922.2
CCDC28B
coiled-coil domain containing 28B
chr3_-_15563229 0.20 ENST00000383786.5
ENST00000383787.2
ENST00000383785.2
ENST00000383788.5
ENST00000603808.1
COLQ
collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase
chr7_-_2883928 0.19 ENST00000275364.3
GNA12
guanine nucleotide binding protein (G protein) alpha 12
chr8_-_12612962 0.19 ENST00000398246.3
LONRF1
LON peptidase N-terminal domain and ring finger 1
chr12_+_16500571 0.19 ENST00000543076.1
ENST00000396210.3
MGST1
microsomal glutathione S-transferase 1
chr20_-_43133491 0.18 ENST00000411544.1
SERINC3
serine incorporator 3
chr19_-_14945933 0.18 ENST00000322301.3
OR7A5
olfactory receptor, family 7, subfamily A, member 5
chr12_-_120966943 0.18 ENST00000552443.1
ENST00000547736.1
ENST00000445328.2
ENST00000547943.1
ENST00000288532.6
COQ5
coenzyme Q5 homolog, methyltransferase (S. cerevisiae)
chr1_+_155278625 0.17 ENST00000368356.4
ENST00000356657.6
FDPS
farnesyl diphosphate synthase
chr22_+_46476192 0.17 ENST00000443490.1
FLJ27365
hsa-mir-4763
chrX_-_153363188 0.17 ENST00000303391.6
MECP2
methyl CpG binding protein 2 (Rett syndrome)
chr17_-_79650818 0.16 ENST00000397498.4
ARL16
ADP-ribosylation factor-like 16
chr16_+_89160269 0.16 ENST00000540697.1
ENST00000406948.3
ENST00000378345.4
ENST00000541755.2
ACSF3
acyl-CoA synthetase family member 3
chr9_-_132383055 0.16 ENST00000372478.4
C9orf50
chromosome 9 open reading frame 50
chr2_-_227050079 0.16 ENST00000423838.1
AC068138.1
AC068138.1
chr20_-_35580104 0.15 ENST00000373694.5
SAMHD1
SAM domain and HD domain 1
chr2_-_183387064 0.15 ENST00000536095.1
ENST00000331935.6
ENST00000358139.2
ENST00000456212.1
PDE1A
phosphodiesterase 1A, calmodulin-dependent
chr7_+_120628731 0.15 ENST00000310396.5
CPED1
cadherin-like and PC-esterase domain containing 1
chrX_+_37639302 0.15 ENST00000545017.1
ENST00000536160.1
CYBB
cytochrome b-245, beta polypeptide
chr17_-_40337470 0.15 ENST00000293330.1
HCRT
hypocretin (orexin) neuropeptide precursor
chr2_-_183387430 0.14 ENST00000410103.1
PDE1A
phosphodiesterase 1A, calmodulin-dependent
chr4_-_171012844 0.14 ENST00000502392.1
AADAT
aminoadipate aminotransferase
chr9_+_136501478 0.14 ENST00000393056.2
ENST00000263611.2
DBH
dopamine beta-hydroxylase (dopamine beta-monooxygenase)
chr8_+_92261516 0.14 ENST00000276609.3
ENST00000309536.2
SLC26A7
solute carrier family 26 (anion exchanger), member 7
chr10_-_105110831 0.14 ENST00000337211.4
PCGF6
polycomb group ring finger 6
chr15_-_58571445 0.14 ENST00000558231.1
ALDH1A2
aldehyde dehydrogenase 1 family, member A2
chr17_+_46970178 0.14 ENST00000393366.2
ENST00000506855.1
ATP5G1
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C1 (subunit 9)
chr5_+_177631523 0.14 ENST00000506339.1
ENST00000355836.5
ENST00000514633.1
ENST00000515193.1
ENST00000506259.1
ENST00000504898.1
HNRNPAB
heterogeneous nuclear ribonucleoprotein A/B
chr17_+_78518617 0.13 ENST00000537330.1
ENST00000570891.1
RPTOR
regulatory associated protein of MTOR, complex 1
chr4_-_19458597 0.13 ENST00000505347.1
RP11-3J1.1
RP11-3J1.1
chr1_-_158173659 0.13 ENST00000415019.1
RP11-404O13.5
RP11-404O13.5
chr12_-_50790267 0.13 ENST00000327337.5
ENST00000543111.1
FAM186A
family with sequence similarity 186, member A
chr2_-_198540719 0.12 ENST00000295049.4
RFTN2
raftlin family member 2
chr5_+_150226085 0.12 ENST00000522154.1
IRGM
immunity-related GTPase family, M
chr6_+_160542870 0.12 ENST00000324965.4
ENST00000457470.2
SLC22A1
solute carrier family 22 (organic cation transporter), member 1
chr2_+_86947296 0.12 ENST00000283632.4
RMND5A
required for meiotic nuclear division 5 homolog A (S. cerevisiae)
chr5_-_137374288 0.12 ENST00000514310.1
FAM13B
family with sequence similarity 13, member B
chr7_-_112635675 0.12 ENST00000447785.1
ENST00000451962.1
AC018464.3
AC018464.3
chr6_-_33385902 0.12 ENST00000374500.5
CUTA
cutA divalent cation tolerance homolog (E. coli)
chr22_-_29137771 0.12 ENST00000439200.1
ENST00000405598.1
ENST00000398017.2
ENST00000425190.2
ENST00000348295.3
ENST00000382578.1
ENST00000382565.1
ENST00000382566.1
ENST00000382580.2
ENST00000328354.6
CHEK2
checkpoint kinase 2
chrX_-_21676442 0.12 ENST00000379499.2
KLHL34
kelch-like family member 34
chr14_-_53258314 0.12 ENST00000216410.3
ENST00000557604.1
GNPNAT1
glucosamine-phosphate N-acetyltransferase 1
chr11_+_95523621 0.12 ENST00000325542.5
ENST00000325486.5
ENST00000544522.1
ENST00000541365.1
CEP57
centrosomal protein 57kDa
chr3_+_115342349 0.12 ENST00000393780.3
GAP43
growth associated protein 43
chr6_-_33385655 0.12 ENST00000440279.3
ENST00000607266.1
CUTA
cutA divalent cation tolerance homolog (E. coli)
chr19_+_42811093 0.12 ENST00000595750.1
PRR19
proline rich 19
chr1_+_155278539 0.11 ENST00000447866.1
FDPS
farnesyl diphosphate synthase
chr1_+_220267429 0.11 ENST00000366922.1
ENST00000302637.5
IARS2
isoleucyl-tRNA synthetase 2, mitochondrial
chr8_-_7243080 0.11 ENST00000400156.4
ZNF705G
zinc finger protein 705G
chr6_-_33385870 0.11 ENST00000488034.1
CUTA
cutA divalent cation tolerance homolog (E. coli)
chr4_-_70080449 0.11 ENST00000446444.1
UGT2B11
UDP glucuronosyltransferase 2 family, polypeptide B11
chr19_+_4153598 0.11 ENST00000078445.2
ENST00000252587.3
ENST00000595923.1
ENST00000602257.1
ENST00000602147.1
CREB3L3
cAMP responsive element binding protein 3-like 3
chr11_+_77532233 0.11 ENST00000525409.1
AAMDC
adipogenesis associated, Mth938 domain containing
chr11_+_77532155 0.10 ENST00000532481.1
ENST00000526415.1
ENST00000393427.2
ENST00000527134.1
ENST00000304716.8
AAMDC
adipogenesis associated, Mth938 domain containing
chr6_+_160542821 0.10 ENST00000366963.4
SLC22A1
solute carrier family 22 (organic cation transporter), member 1
chr19_+_36632485 0.10 ENST00000586963.1
CAPNS1
calpain, small subunit 1
chr4_-_66536057 0.10 ENST00000273854.3
EPHA5
EPH receptor A5
chr17_-_40829026 0.09 ENST00000412503.1
PLEKHH3
pleckstrin homology domain containing, family H (with MyTH4 domain) member 3
chr19_+_36632204 0.09 ENST00000592354.1
CAPNS1
calpain, small subunit 1
chr6_-_33385823 0.09 ENST00000494751.1
ENST00000374496.3
CUTA
cutA divalent cation tolerance homolog (E. coli)
chr11_-_121986923 0.09 ENST00000560104.1
BLID
BH3-like motif containing, cell death inducer

Network of associatons between targets according to the STRING database.

First level regulatory network of ISX

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.8 GO:0090119 vesicle-mediated cholesterol transport(GO:0090119)
0.6 2.6 GO:1904482 response to tetrahydrofolate(GO:1904481) cellular response to tetrahydrofolate(GO:1904482)
0.6 1.7 GO:0099558 maintenance of synapse structure(GO:0099558)
0.3 1.0 GO:0060829 regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060827) negative regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060829)
0.3 0.9 GO:0009786 regulation of asymmetric cell division(GO:0009786)
0.2 0.7 GO:0006258 UDP-glucose catabolic process(GO:0006258)
0.2 1.7 GO:0031536 positive regulation of exit from mitosis(GO:0031536)
0.2 0.5 GO:0071140 resolution of recombination intermediates(GO:0071139) resolution of mitotic recombination intermediates(GO:0071140)
0.2 0.5 GO:0051795 positive regulation of catagen(GO:0051795) activation of meiosis(GO:0090427)
0.2 0.5 GO:0071449 cellular response to lipid hydroperoxide(GO:0071449)
0.2 1.0 GO:1903438 regulation of cytokinetic process(GO:0032954) regulation of mitotic cytokinetic process(GO:1903436) positive regulation of mitotic cytokinetic process(GO:1903438) positive regulation of mitotic cytokinesis(GO:1903490)
0.2 0.3 GO:0000454 snoRNA guided rRNA pseudouridine synthesis(GO:0000454)
0.1 2.0 GO:0001887 selenium compound metabolic process(GO:0001887)
0.1 1.3 GO:0031120 snRNA pseudouridine synthesis(GO:0031120)
0.1 1.3 GO:0046485 ether lipid metabolic process(GO:0046485)
0.1 0.5 GO:0090410 malonate catabolic process(GO:0090410)
0.1 1.3 GO:0042373 vitamin K metabolic process(GO:0042373)
0.1 0.9 GO:0060136 embryonic process involved in female pregnancy(GO:0060136)
0.1 1.0 GO:0010571 positive regulation of nuclear cell cycle DNA replication(GO:0010571)
0.1 0.3 GO:0042414 epinephrine metabolic process(GO:0042414) cellular response to lead ion(GO:0071284)
0.1 1.0 GO:0014722 regulation of skeletal muscle contraction by calcium ion signaling(GO:0014722)
0.1 1.3 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.1 0.3 GO:0070092 regulation of glucagon secretion(GO:0070092)
0.1 0.3 GO:0033384 geranyl diphosphate metabolic process(GO:0033383) geranyl diphosphate biosynthetic process(GO:0033384) farnesyl diphosphate biosynthetic process(GO:0045337)
0.1 0.3 GO:0010814 substance P catabolic process(GO:0010814) calcitonin catabolic process(GO:0010816) endothelin maturation(GO:0034959)
0.1 0.7 GO:0045654 positive regulation of megakaryocyte differentiation(GO:0045654)
0.0 0.1 GO:0009405 pathogenesis(GO:0009405)
0.0 0.3 GO:0000255 allantoin metabolic process(GO:0000255)
0.0 0.2 GO:0048241 epinephrine transport(GO:0048241)
0.0 0.3 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.0 0.6 GO:0071394 cellular response to testosterone stimulus(GO:0071394)
0.0 1.4 GO:0046597 negative regulation of viral entry into host cell(GO:0046597)
0.0 0.6 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.0 2.0 GO:0007339 binding of sperm to zona pellucida(GO:0007339)
0.0 0.1 GO:1903926 signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926)
0.0 0.2 GO:1904844 response to L-glutamine(GO:1904844) cellular response to L-glutamine(GO:1904845)
0.0 0.5 GO:0097091 synaptic vesicle clustering(GO:0097091)
0.0 1.2 GO:0008211 glucocorticoid metabolic process(GO:0008211)
0.0 0.4 GO:0030091 protein repair(GO:0030091)
0.0 0.2 GO:0006203 dGTP catabolic process(GO:0006203)
0.0 0.1 GO:0051970 negative regulation of transmission of nerve impulse(GO:0051970)
0.0 0.3 GO:0075525 viral translational termination-reinitiation(GO:0075525)
0.0 0.5 GO:0043248 proteasome assembly(GO:0043248)
0.0 0.1 GO:0006428 isoleucyl-tRNA aminoacylation(GO:0006428)
0.0 0.2 GO:0015722 canalicular bile acid transport(GO:0015722) pyrimidine nucleobase transport(GO:0015855) purine nucleobase transmembrane transport(GO:1904823)
0.0 1.0 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.0 0.1 GO:0006581 acetylcholine catabolic process in synaptic cleft(GO:0001507) acetylcholine catabolic process(GO:0006581)
0.0 0.7 GO:1903541 regulation of exosomal secretion(GO:1903541)
0.0 0.1 GO:0061762 CAMKK-AMPK signaling cascade(GO:0061762)
0.0 0.1 GO:0033512 L-lysine catabolic process to acetyl-CoA via saccharopine(GO:0033512) L-kynurenine metabolic process(GO:0097052)
0.0 0.2 GO:0006931 substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.0 0.1 GO:0042421 norepinephrine biosynthetic process(GO:0042421)
0.0 0.5 GO:0033197 response to vitamin E(GO:0033197)
0.0 0.2 GO:0009597 detection of virus(GO:0009597)
0.0 0.2 GO:0048022 negative regulation of melanin biosynthetic process(GO:0048022) negative regulation of secondary metabolite biosynthetic process(GO:1900377)
0.0 0.2 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0 0.1 GO:0060723 spongiotrophoblast cell proliferation(GO:0060720) regulation of spongiotrophoblast cell proliferation(GO:0060721) cell proliferation involved in embryonic placenta development(GO:0060722) regulation of cell proliferation involved in embryonic placenta development(GO:0060723)
0.0 0.4 GO:0046069 cGMP catabolic process(GO:0046069)
0.0 0.3 GO:0010826 negative regulation of centrosome duplication(GO:0010826)
0.0 0.1 GO:0035799 ureter maturation(GO:0035799)
0.0 0.2 GO:0035520 monoubiquitinated protein deubiquitination(GO:0035520)
0.0 0.1 GO:0006041 glucosamine metabolic process(GO:0006041)
0.0 0.4 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0 0.1 GO:0071233 cellular response to leucine(GO:0071233)
0.0 0.7 GO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.0 0.2 GO:0032596 protein transport into membrane raft(GO:0032596)
0.0 0.7 GO:0071173 mitotic spindle assembly checkpoint(GO:0007094) spindle assembly checkpoint(GO:0071173)
0.0 0.4 GO:0042438 melanin biosynthetic process(GO:0042438)
0.0 0.4 GO:0007141 male meiosis I(GO:0007141)
0.0 0.6 GO:0006506 GPI anchor biosynthetic process(GO:0006506)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.7 GO:0044301 climbing fiber(GO:0044301)
0.2 1.6 GO:0090661 box H/ACA scaRNP complex(GO:0072589) box H/ACA telomerase RNP complex(GO:0090661)
0.2 0.7 GO:1990298 mitotic checkpoint complex(GO:0033597) bub1-bub3 complex(GO:1990298)
0.1 0.9 GO:0035976 AP1 complex(GO:0035976)
0.1 0.5 GO:0035061 interchromatin granule(GO:0035061)
0.1 0.9 GO:0072687 meiotic spindle(GO:0072687)
0.1 0.5 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.1 0.1 GO:0034657 GID complex(GO:0034657)
0.1 0.3 GO:0031302 intrinsic component of endosome membrane(GO:0031302)
0.0 1.0 GO:0070938 contractile ring(GO:0070938)
0.0 0.7 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.0 1.7 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.7 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.6 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 0.2 GO:0000275 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275)
0.0 0.5 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.5 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.0 0.2 GO:0097362 MCM8-MCM9 complex(GO:0097362)
0.0 1.0 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.5 GO:0000815 ESCRT III complex(GO:0000815)
0.0 0.4 GO:0045277 respiratory chain complex IV(GO:0045277)
0.0 0.1 GO:0033565 ESCRT-0 complex(GO:0033565)
0.0 1.7 GO:0031903 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 0.1 GO:0032584 growth cone membrane(GO:0032584)
0.0 0.2 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 0.9 GO:0016235 aggresome(GO:0016235)
0.0 0.9 GO:0045095 keratin filament(GO:0045095)
0.0 0.3 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.8 GO:0047374 methylumbelliferyl-acetate deacetylase activity(GO:0047374)
0.5 2.6 GO:0070905 serine binding(GO:0070905)
0.4 2.0 GO:0098626 methylselenol reductase activity(GO:0098625) methylseleninic acid reductase activity(GO:0098626)
0.3 1.3 GO:0047057 oxidoreductase activity, acting on the CH-OH group of donors, disulfide as acceptor(GO:0016900) vitamin-K-epoxide reductase (warfarin-sensitive) activity(GO:0047057)
0.3 1.3 GO:0052740 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
0.2 1.6 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.1 0.7 GO:0044378 non-sequence-specific DNA binding, bending(GO:0044378)
0.1 0.5 GO:0090409 malonyl-CoA synthetase activity(GO:0090409)
0.1 0.4 GO:0033981 D-dopachrome decarboxylase activity(GO:0033981)
0.1 0.3 GO:0016532 superoxide dismutase copper chaperone activity(GO:0016532) copper-dependent protein binding(GO:0032767)
0.1 0.4 GO:0008113 peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.1 0.3 GO:0004337 dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
0.1 0.3 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.1 0.2 GO:0005277 acetylcholine transmembrane transporter activity(GO:0005277) secondary active organic cation transmembrane transporter activity(GO:0008513) acetate ester transmembrane transporter activity(GO:1901375)
0.1 0.2 GO:0005275 amine transmembrane transporter activity(GO:0005275)
0.1 0.4 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.0 0.1 GO:0047536 2-aminoadipate transaminase activity(GO:0047536)
0.0 0.6 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.1 GO:0001156 TFIIIC-class transcription factor binding(GO:0001156)
0.0 0.5 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.0 0.7 GO:0070569 uridylyltransferase activity(GO:0070569)
0.0 0.2 GO:0043532 angiostatin binding(GO:0043532)
0.0 1.7 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 0.7 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 0.1 GO:0004822 isoleucine-tRNA ligase activity(GO:0004822)
0.0 0.2 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.0 1.0 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.4 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.0 0.1 GO:0004739 pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.0 1.1 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 0.5 GO:0043295 glutathione binding(GO:0043295)
0.0 0.5 GO:0032794 GTPase activating protein binding(GO:0032794)
0.0 0.1 GO:0010309 acireductone dioxygenase [iron(II)-requiring] activity(GO:0010309)
0.0 0.2 GO:0032554 purine deoxyribonucleotide binding(GO:0032554)
0.0 0.3 GO:0033038 bitter taste receptor activity(GO:0033038)
0.0 0.4 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.0 0.1 GO:0016715 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.0 1.0 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.0 0.2 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 0.4 GO:0015002 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.1 GO:0010385 double-stranded methylated DNA binding(GO:0010385)
0.0 0.0 GO:0032038 myosin II heavy chain binding(GO:0032038)
0.0 0.0 GO:0050528 acyloxyacyl hydrolase activity(GO:0050528)
0.0 0.1 GO:0035727 lysophosphatidic acid binding(GO:0035727)
0.0 0.1 GO:0051434 BH3 domain binding(GO:0051434)
0.0 0.1 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 0.2 GO:0015194 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.8 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 0.6 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 0.9 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 2.6 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 0.3 PID IL5 PATHWAY IL5-mediated signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.3 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.1 1.3 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.1 2.3 REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS Genes involved in Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components
0.1 0.7 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0 2.0 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 1.0 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.0 0.7 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 1.3 REACTOME EXTENSION OF TELOMERES Genes involved in Extension of Telomeres
0.0 2.6 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 0.2 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.0 0.7 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.9 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0 0.2 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.0 0.4 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 0.6 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.0 0.5 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.7 REACTOME MRNA 3 END PROCESSING Genes involved in mRNA 3'-end processing
0.0 0.2 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins