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SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for JDP2

Z-value: 2.15

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Transcription factors associated with JDP2

Gene Symbol Gene ID Gene Info
JDP2
ENSG00000140044.8 Jun dimerization protein 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
JDP2hg19_v2_chr14_+_75894391_758944350.371.0e-01Click!

Activity profile of JDP2 motif

Sorted Z-values of JDP2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr19_-_56056888 11.69 ENST00000592464.1
ENST00000420723.3
SBK3
SH3 domain binding kinase family, member 3
chr11_-_102401469 10.77 ENST00000260227.4
MMP7
matrix metallopeptidase 7 (matrilysin, uterine)
chr20_-_62129163 9.50 ENST00000298049.7
EEF1A2
eukaryotic translation elongation factor 1 alpha 2
chr8_-_27472198 7.75 ENST00000519472.1
ENST00000523589.1
ENST00000522413.1
ENST00000523396.1
ENST00000560366.1
CLU
clusterin
chrY_+_15016725 7.64 ENST00000336079.3
DDX3Y
DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
chr20_+_43029911 7.39 ENST00000443598.2
ENST00000316099.4
ENST00000415691.2
HNF4A
hepatocyte nuclear factor 4, alpha
chr9_+_118950325 7.28 ENST00000534838.1
PAPPA
pregnancy-associated plasma protein A, pappalysin 1
chr1_+_156084461 6.85 ENST00000347559.2
ENST00000361308.4
ENST00000368300.4
ENST00000368299.3
LMNA
lamin A/C
chrX_-_15288154 6.84 ENST00000380483.3
ENST00000380485.3
ENST00000380488.4
ASB9
ankyrin repeat and SOCS box containing 9
chr17_+_4853442 6.77 ENST00000522301.1
ENO3
enolase 3 (beta, muscle)
chr16_-_57798253 6.58 ENST00000565270.1
KIFC3
kinesin family member C3
chr16_-_69760409 6.29 ENST00000561500.1
ENST00000439109.2
ENST00000564043.1
ENST00000379046.2
ENST00000379047.3
NQO1
NAD(P)H dehydrogenase, quinone 1
chr10_+_17270214 6.25 ENST00000544301.1
VIM
vimentin
chr5_-_75919253 6.25 ENST00000296641.4
F2RL2
coagulation factor II (thrombin) receptor-like 2
chr20_-_17539456 6.10 ENST00000544874.1
ENST00000377868.2
BFSP1
beaded filament structural protein 1, filensin
chr17_+_48712206 5.96 ENST00000427699.1
ENST00000285238.8
ABCC3
ATP-binding cassette, sub-family C (CFTR/MRP), member 3
chr7_+_30960915 5.89 ENST00000441328.2
ENST00000409899.1
ENST00000409611.1
AQP1
aquaporin 1 (Colton blood group)
chr9_-_123639304 5.56 ENST00000436309.1
PHF19
PHD finger protein 19
chr1_-_153521597 5.56 ENST00000368712.1
S100A3
S100 calcium binding protein A3
chr12_+_52695617 5.53 ENST00000293525.5
KRT86
keratin 86
chr2_+_87754989 5.49 ENST00000409898.2
ENST00000419680.2
ENST00000414584.1
ENST00000455131.1
LINC00152
long intergenic non-protein coding RNA 152
chr5_-_90610200 5.49 ENST00000511918.1
ENST00000513626.1
ENST00000607854.1
LUCAT1
RP11-213H15.4
lung cancer associated transcript 1 (non-protein coding)
RP11-213H15.4
chr12_-_53343602 5.44 ENST00000546897.1
ENST00000552551.1
KRT8
keratin 8
chr12_-_53343560 5.33 ENST00000548998.1
KRT8
keratin 8
chr17_+_48712138 4.96 ENST00000515707.1
ABCC3
ATP-binding cassette, sub-family C (CFTR/MRP), member 3
chr5_-_75919217 4.95 ENST00000504899.1
F2RL2
coagulation factor II (thrombin) receptor-like 2
chr16_-_30997533 4.95 ENST00000602217.1
AC135048.1
Uncharacterized protein
chr4_+_84457529 4.75 ENST00000264409.4
AGPAT9
1-acylglycerol-3-phosphate O-acyltransferase 9
chr11_-_2924720 4.75 ENST00000455942.2
SLC22A18AS
solute carrier family 22 (organic cation transporter), member 18 antisense
chr4_+_84457250 4.71 ENST00000395226.2
AGPAT9
1-acylglycerol-3-phosphate O-acyltransferase 9
chr12_-_53343633 4.69 ENST00000546826.1
KRT8
keratin 8
chr1_-_153521714 4.47 ENST00000368713.3
S100A3
S100 calcium binding protein A3
chr1_+_156096336 4.45 ENST00000504687.1
ENST00000473598.2
LMNA
lamin A/C
chr9_-_123638633 4.44 ENST00000456291.1
PHF19
PHD finger protein 19
chr3_+_48507210 4.40 ENST00000433541.1
ENST00000422277.2
ENST00000436480.2
ENST00000444177.1
TREX1
three prime repair exonuclease 1
chr17_-_27045427 4.32 ENST00000301043.6
ENST00000412625.1
RAB34
RAB34, member RAS oncogene family
chr2_+_152214098 4.30 ENST00000243347.3
TNFAIP6
tumor necrosis factor, alpha-induced protein 6
chr13_-_67802549 4.26 ENST00000328454.5
ENST00000377865.2
PCDH9
protocadherin 9
chr12_-_102591604 4.17 ENST00000329406.4
PMCH
pro-melanin-concentrating hormone
chr16_+_15596123 4.16 ENST00000452191.2
C16orf45
chromosome 16 open reading frame 45
chr2_-_175712270 4.13 ENST00000295497.7
ENST00000444394.1
CHN1
chimerin 1
chr3_+_98699880 3.84 ENST00000473756.1
LINC00973
long intergenic non-protein coding RNA 973
chr11_+_58874701 3.79 ENST00000529618.1
ENST00000534403.1
ENST00000343597.3
FAM111B
family with sequence similarity 111, member B
chr17_-_27045165 3.75 ENST00000436730.3
ENST00000450529.1
ENST00000583538.1
ENST00000419712.3
ENST00000580843.2
ENST00000582934.1
ENST00000415040.2
ENST00000353676.5
ENST00000453384.3
ENST00000447716.1
RAB34
RAB34, member RAS oncogene family
chr7_-_47492782 3.69 ENST00000413551.1
TNS3
tensin 3
chr12_-_105352047 3.67 ENST00000432951.1
ENST00000415674.1
ENST00000424946.1
SLC41A2
solute carrier family 41 (magnesium transporter), member 2
chr3_+_48507621 3.64 ENST00000456089.1
TREX1
three prime repair exonuclease 1
chr17_-_27044903 3.60 ENST00000395245.3
RAB34
RAB34, member RAS oncogene family
chr19_-_46285646 3.58 ENST00000458663.2
DMPK
dystrophia myotonica-protein kinase
chr2_+_10262442 3.55 ENST00000360566.2
RRM2
ribonucleotide reductase M2
chr17_+_25799008 3.55 ENST00000583370.1
ENST00000398988.3
ENST00000268763.6
KSR1
kinase suppressor of ras 1
chr10_+_88854926 3.42 ENST00000298784.1
ENST00000298786.4
FAM35A
family with sequence similarity 35, member A
chr15_-_54025300 3.41 ENST00000559418.1
WDR72
WD repeat domain 72
chr3_+_69134124 3.39 ENST00000478935.1
ARL6IP5
ADP-ribosylation-like factor 6 interacting protein 5
chr3_+_28283069 3.38 ENST00000466830.1
ENST00000423894.1
CMC1
C-x(9)-C motif containing 1
chr12_+_7023491 3.38 ENST00000541477.1
ENST00000229277.1
ENO2
enolase 2 (gamma, neuronal)
chr10_+_94594351 3.31 ENST00000371552.4
EXOC6
exocyst complex component 6
chr12_+_7023735 3.27 ENST00000538763.1
ENST00000544774.1
ENST00000545045.2
ENO2
enolase 2 (gamma, neuronal)
chr17_-_27044810 3.24 ENST00000395242.2
RAB34
RAB34, member RAS oncogene family
chr7_-_155604967 3.23 ENST00000297261.2
SHH
sonic hedgehog
chr12_-_6960407 3.18 ENST00000540683.1
ENST00000229265.6
ENST00000535406.1
ENST00000422785.3
CDCA3
cell division cycle associated 3
chr2_+_87754887 3.10 ENST00000409054.1
ENST00000331944.6
ENST00000409139.1
LINC00152
long intergenic non-protein coding RNA 152
chr1_-_244006528 3.07 ENST00000336199.5
ENST00000263826.5
AKT3
v-akt murine thymoma viral oncogene homolog 3
chr2_-_145275228 3.05 ENST00000427902.1
ENST00000409487.3
ENST00000470879.1
ENST00000435831.1
ZEB2
zinc finger E-box binding homeobox 2
chr11_+_67250490 2.99 ENST00000528641.2
ENST00000279146.3
AIP
aryl hydrocarbon receptor interacting protein
chr2_+_87755054 2.89 ENST00000423846.1
LINC00152
long intergenic non-protein coding RNA 152
chr2_+_46926048 2.83 ENST00000306503.5
SOCS5
suppressor of cytokine signaling 5
chr17_-_70417365 2.83 ENST00000580948.1
LINC00511
long intergenic non-protein coding RNA 511
chr2_+_202122826 2.82 ENST00000413726.1
CASP8
caspase 8, apoptosis-related cysteine peptidase
chr2_-_175711978 2.80 ENST00000409089.2
CHN1
chimerin 1
chr12_-_53297432 2.78 ENST00000546900.1
KRT8
keratin 8
chr5_+_72143988 2.74 ENST00000506351.2
TNPO1
transportin 1
chr11_+_58874658 2.73 ENST00000411426.1
FAM111B
family with sequence similarity 111, member B
chr17_-_27045405 2.73 ENST00000430132.2
RAB34
RAB34, member RAS oncogene family
chr11_-_2950642 2.72 ENST00000314222.4
PHLDA2
pleckstrin homology-like domain, family A, member 2
chr1_+_33722080 2.69 ENST00000483388.1
ENST00000539719.1
ZNF362
zinc finger protein 362
chr22_-_43398442 2.61 ENST00000422336.1
PACSIN2
protein kinase C and casein kinase substrate in neurons 2
chr19_-_51872233 2.59 ENST00000601435.1
ENST00000291715.1
CLDND2
claudin domain containing 2
chr2_-_175712479 2.57 ENST00000443238.1
CHN1
chimerin 1
chr16_-_31161380 2.55 ENST00000569305.1
ENST00000418068.2
ENST00000268281.4
PRSS36
protease, serine, 36
chr8_+_40018977 2.45 ENST00000520487.1
RP11-470M17.2
RP11-470M17.2
chr14_-_51562037 2.42 ENST00000338969.5
TRIM9
tripartite motif containing 9
chr14_-_51561784 2.33 ENST00000360392.4
TRIM9
tripartite motif containing 9
chr17_-_47785504 2.32 ENST00000514907.1
ENST00000503334.1
ENST00000508520.1
SLC35B1
solute carrier family 35, member B1
chr15_+_89182156 2.30 ENST00000379224.5
ISG20
interferon stimulated exonuclease gene 20kDa
chr4_-_987217 2.24 ENST00000361661.2
ENST00000398516.2
SLC26A1
solute carrier family 26 (anion exchanger), member 1
chr2_-_145275109 2.21 ENST00000431672.2
ZEB2
zinc finger E-box binding homeobox 2
chr2_-_11606275 2.19 ENST00000381525.3
ENST00000362009.4
E2F6
E2F transcription factor 6
chr8_-_123139423 2.19 ENST00000523792.1
RP11-398G24.2
RP11-398G24.2
chr5_+_169758393 2.19 ENST00000521471.1
ENST00000518357.1
ENST00000436248.3
CTB-114C7.3
CTB-114C7.3
chr17_+_80317121 2.19 ENST00000333437.4
TEX19
testis expressed 19
chr3_-_149293990 2.18 ENST00000472417.1
WWTR1
WW domain containing transcription regulator 1
chr2_+_7073174 2.14 ENST00000416587.1
RNF144A
ring finger protein 144A
chrX_+_153770421 2.14 ENST00000369609.5
ENST00000369607.1
IKBKG
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
chr16_+_50300427 2.12 ENST00000394697.2
ENST00000566433.2
ENST00000538642.1
ADCY7
adenylate cyclase 7
chr15_+_65843130 2.06 ENST00000569894.1
PTPLAD1
protein tyrosine phosphatase-like A domain containing 1
chr11_-_2924970 2.01 ENST00000533594.1
SLC22A18AS
solute carrier family 22 (organic cation transporter), member 18 antisense
chr17_-_47786375 1.99 ENST00000511657.1
SLC35B1
solute carrier family 35, member B1
chr11_+_122526383 1.96 ENST00000284273.5
UBASH3B
ubiquitin associated and SH3 domain containing B
chr14_-_23426231 1.92 ENST00000556915.1
HAUS4
HAUS augmin-like complex, subunit 4
chr2_+_202122703 1.88 ENST00000447616.1
ENST00000358485.4
CASP8
caspase 8, apoptosis-related cysteine peptidase
chr2_+_27505260 1.87 ENST00000380075.2
ENST00000296098.4
TRIM54
tripartite motif containing 54
chr15_+_75335604 1.87 ENST00000563393.1
PPCDC
phosphopantothenoylcysteine decarboxylase
chrX_-_154493791 1.84 ENST00000369454.3
RAB39B
RAB39B, member RAS oncogene family
chr11_-_75201791 1.80 ENST00000529721.1
GDPD5
glycerophosphodiester phosphodiesterase domain containing 5
chr15_+_89182178 1.78 ENST00000559876.1
ISG20
interferon stimulated exonuclease gene 20kDa
chr2_-_121624973 1.77 ENST00000603720.1
RP11-297J22.1
RP11-297J22.1
chr2_+_69201705 1.74 ENST00000377938.2
GKN1
gastrokine 1
chr16_+_2083265 1.73 ENST00000565855.1
ENST00000566198.1
SLC9A3R2
solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2
chr11_+_20620946 1.71 ENST00000525748.1
SLC6A5
solute carrier family 6 (neurotransmitter transporter), member 5
chrX_-_19689106 1.66 ENST00000379716.1
SH3KBP1
SH3-domain kinase binding protein 1
chr8_-_38386175 1.60 ENST00000437935.2
ENST00000358138.1
C8orf86
chromosome 8 open reading frame 86
chr11_-_10920838 1.59 ENST00000503469.2
CTD-2003C8.2
CTD-2003C8.2
chr17_-_53800217 1.58 ENST00000424486.2
TMEM100
transmembrane protein 100
chr17_+_76311791 1.55 ENST00000586321.1
AC061992.2
AC061992.2
chr15_+_89181974 1.55 ENST00000306072.5
ISG20
interferon stimulated exonuclease gene 20kDa
chr5_+_179247759 1.55 ENST00000389805.4
ENST00000504627.1
ENST00000402874.3
ENST00000510187.1
SQSTM1
sequestosome 1
chr1_-_246580705 1.52 ENST00000541742.1
SMYD3
SET and MYND domain containing 3
chr11_+_82783097 1.50 ENST00000501011.2
ENST00000527627.1
ENST00000526795.1
ENST00000533528.1
ENST00000533708.1
ENST00000534499.1
RAB30-AS1
RAB30 antisense RNA 1 (head to head)
chr6_-_31745085 1.49 ENST00000375686.3
ENST00000447450.1
VWA7
von Willebrand factor A domain containing 7
chr5_+_135394840 1.48 ENST00000503087.1
TGFBI
transforming growth factor, beta-induced, 68kDa
chr2_-_224467002 1.48 ENST00000421386.1
ENST00000433889.1
SCG2
secretogranin II
chr9_+_123906331 1.45 ENST00000431571.1
CNTRL
centriolin
chr3_-_191000172 1.45 ENST00000427544.2
UTS2B
urotensin 2B
chr10_+_104155450 1.43 ENST00000471698.1
ENST00000189444.6
NFKB2
nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
chr3_-_45957088 1.41 ENST00000539217.1
LZTFL1
leucine zipper transcription factor-like 1
chr16_+_31366536 1.40 ENST00000562522.1
ITGAX
integrin, alpha X (complement component 3 receptor 4 subunit)
chr17_-_1553346 1.40 ENST00000301336.6
RILP
Rab interacting lysosomal protein
chr19_-_56047661 1.39 ENST00000344158.3
SBK2
SH3 domain binding kinase family, member 2
chr12_-_56101647 1.38 ENST00000347027.6
ENST00000257879.6
ENST00000257880.7
ENST00000394230.2
ENST00000394229.2
ITGA7
integrin, alpha 7
chr7_-_135433460 1.38 ENST00000415751.1
FAM180A
family with sequence similarity 180, member A
chr14_+_32476072 1.36 ENST00000556949.1
RP11-187E13.2
Uncharacterized protein
chr17_-_8263538 1.35 ENST00000535173.1
AC135178.1
HCG1985372; Uncharacterized protein; cDNA FLJ37541 fis, clone BRCAN2026340
chr3_-_45957534 1.35 ENST00000536047.1
LZTFL1
leucine zipper transcription factor-like 1
chr19_+_38880695 1.35 ENST00000587947.1
ENST00000338502.4
SPRED3
sprouty-related, EVH1 domain containing 3
chr14_+_73525265 1.32 ENST00000525161.1
RBM25
RNA binding motif protein 25
chr6_-_31745037 1.30 ENST00000375688.4
VWA7
von Willebrand factor A domain containing 7
chr14_+_38065052 1.27 ENST00000556845.1
TTC6
tetratricopeptide repeat domain 6
chr1_+_154378049 1.26 ENST00000512471.1
IL6R
interleukin 6 receptor
chr4_+_120056939 1.26 ENST00000307128.5
MYOZ2
myozenin 2
chr5_-_94417562 1.26 ENST00000505465.1
MCTP1
multiple C2 domains, transmembrane 1
chr18_+_2846972 1.24 ENST00000254528.3
EMILIN2
elastin microfibril interfacer 2
chr20_-_48782639 1.24 ENST00000435301.2
RP11-112L6.3
RP11-112L6.3
chr5_-_67730240 1.24 ENST00000507733.1
CTC-537E7.3
CTC-537E7.3
chr2_-_11605966 1.24 ENST00000307236.4
ENST00000542100.1
ENST00000546212.1
E2F6
E2F transcription factor 6
chr10_-_31288398 1.24 ENST00000538351.2
ZNF438
zinc finger protein 438
chr6_-_84140757 1.23 ENST00000541327.1
ENST00000369705.3
ENST00000543031.1
ME1
malic enzyme 1, NADP(+)-dependent, cytosolic
chr19_-_5903714 1.22 ENST00000586349.1
ENST00000585661.1
ENST00000308961.4
ENST00000592634.1
ENST00000418389.2
ENST00000252675.5
AC024592.12
NDUFA11
FUT5
Uncharacterized protein
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 11, 14.7kDa
fucosyltransferase 5 (alpha (1,3) fucosyltransferase)
chr17_-_55162360 1.22 ENST00000576871.1
ENST00000576313.1
RP11-166P13.3
RP11-166P13.3
chr10_-_21463116 1.22 ENST00000417816.2
NEBL
nebulette
chr19_-_45927622 1.21 ENST00000300853.3
ENST00000589165.1
ERCC1
excision repair cross-complementing rodent repair deficiency, complementation group 1 (includes overlapping antisense sequence)
chr3_+_57094469 1.21 ENST00000334325.1
SPATA12
spermatogenesis associated 12
chr3_-_122512619 1.20 ENST00000383659.1
ENST00000306103.2
HSPBAP1
HSPB (heat shock 27kDa) associated protein 1
chr2_-_65593784 1.18 ENST00000443619.2
SPRED2
sprouty-related, EVH1 domain containing 2
chr17_+_55162453 1.18 ENST00000575322.1
ENST00000337714.3
ENST00000314126.3
AKAP1
A kinase (PRKA) anchor protein 1
chr17_-_38911580 1.15 ENST00000312150.4
KRT25
keratin 25
chr9_-_34662651 1.14 ENST00000259631.4
CCL27
chemokine (C-C motif) ligand 27
chr17_-_73775839 1.13 ENST00000592643.1
ENST00000591890.1
ENST00000587171.1
ENST00000254810.4
ENST00000589599.1
H3F3B
H3 histone, family 3B (H3.3B)
chr11_+_57308979 1.12 ENST00000457912.1
SMTNL1
smoothelin-like 1
chr13_-_36429763 1.09 ENST00000379893.1
DCLK1
doublecortin-like kinase 1
chr7_-_135433534 1.09 ENST00000338588.3
FAM180A
family with sequence similarity 180, member A
chr14_-_54317532 1.08 ENST00000418927.1
AL162759.1
AL162759.1
chr17_+_79650962 1.07 ENST00000329138.4
HGS
hepatocyte growth factor-regulated tyrosine kinase substrate
chr14_+_103800513 1.06 ENST00000560338.1
ENST00000560763.1
ENST00000558316.1
ENST00000558265.1
EIF5
eukaryotic translation initiation factor 5
chr11_-_10920714 1.05 ENST00000533941.1
CTD-2003C8.2
CTD-2003C8.2
chr12_+_48152774 1.05 ENST00000549243.1
SLC48A1
solute carrier family 48 (heme transporter), member 1
chr16_-_75301886 1.05 ENST00000393422.2
BCAR1
breast cancer anti-estrogen resistance 1
chr17_+_75315654 1.04 ENST00000590595.1
SEPT9
septin 9
chr17_-_47287928 1.04 ENST00000507680.1
GNGT2
guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2
chr14_+_103801140 1.04 ENST00000561325.1
ENST00000392715.2
ENST00000559130.1
ENST00000559532.1
ENST00000558506.1
EIF5
eukaryotic translation initiation factor 5
chr12_-_719573 1.03 ENST00000397265.3
NINJ2
ninjurin 2
chr1_-_235116495 1.03 ENST00000549744.1
RP11-443B7.3
RP11-443B7.3
chr17_+_47287749 1.02 ENST00000419580.2
ABI3
ABI family, member 3
chrX_-_20074895 1.01 ENST00000543767.1
MAP7D2
MAP7 domain containing 2
chr15_+_57211318 1.01 ENST00000557947.1
TCF12
transcription factor 12
chr2_-_145275211 0.99 ENST00000462355.1
ZEB2
zinc finger E-box binding homeobox 2
chr13_+_53602894 0.99 ENST00000219022.2
OLFM4
olfactomedin 4
chr15_-_60690163 0.99 ENST00000558998.1
ENST00000560165.1
ENST00000557986.1
ENST00000559780.1
ENST00000559467.1
ENST00000559956.1
ENST00000332680.4
ENST00000396024.3
ENST00000421017.2
ENST00000560466.1
ENST00000558132.1
ENST00000559113.1
ENST00000557906.1
ENST00000558558.1
ENST00000560468.1
ENST00000559370.1
ENST00000558169.1
ENST00000559725.1
ENST00000558985.1
ENST00000451270.2
ANXA2
annexin A2
chr12_+_113860042 0.99 ENST00000403593.4
SDSL
serine dehydratase-like
chr12_+_113860160 0.93 ENST00000553248.1
ENST00000345635.4
ENST00000547802.1
SDSL
serine dehydratase-like
chrX_-_48901012 0.93 ENST00000315869.7
TFE3
transcription factor binding to IGHM enhancer 3
chr16_+_30211181 0.92 ENST00000395138.2
SULT1A3
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 3
chr16_+_31366455 0.91 ENST00000268296.4
ITGAX
integrin, alpha X (complement component 3 receptor 4 subunit)
chr11_-_84028339 0.88 ENST00000398301.2
DLG2
discs, large homolog 2 (Drosophila)
chr10_-_105238997 0.87 ENST00000369783.4
CALHM3
calcium homeostasis modulator 3
chr9_+_140135665 0.86 ENST00000340384.4
TUBB4B
tubulin, beta 4B class IVb
chr11_-_57417367 0.85 ENST00000534810.1
YPEL4
yippee-like 4 (Drosophila)
chr1_-_160231451 0.85 ENST00000495887.1
DCAF8
DDB1 and CUL4 associated factor 8
chr9_-_91793675 0.84 ENST00000375835.4
ENST00000375830.1
SHC3
SHC (Src homology 2 domain containing) transforming protein 3
chr17_-_39156138 0.83 ENST00000391587.1
KRTAP3-2
keratin associated protein 3-2
chr11_-_57417405 0.82 ENST00000524669.1
ENST00000300022.3
YPEL4
yippee-like 4 (Drosophila)
chr6_+_63921351 0.81 ENST00000370659.1
FKBP1C
FK506 binding protein 1C
chr7_+_872107 0.81 ENST00000405266.1
ENST00000401592.1
ENST00000403868.1
ENST00000425407.2
SUN1
Sad1 and UNC84 domain containing 1
chr2_-_220173685 0.79 ENST00000423636.2
ENST00000442029.1
ENST00000412847.1
PTPRN
protein tyrosine phosphatase, receptor type, N
chr11_-_84028180 0.79 ENST00000280241.8
DLG2
discs, large homolog 2 (Drosophila)
chr17_+_66245341 0.78 ENST00000577985.1
AMZ2
archaelysin family metallopeptidase 2
chr6_+_122720681 0.78 ENST00000368455.4
ENST00000452194.1
HSF2
heat shock transcription factor 2
chr12_-_105352080 0.77 ENST00000433540.1
SLC41A2
solute carrier family 41 (magnesium transporter), member 2
chr11_-_68780824 0.76 ENST00000441623.1
ENST00000309099.6
MRGPRF
MAS-related GPR, member F
chr6_-_31704282 0.75 ENST00000375784.3
ENST00000375779.2
CLIC1
chloride intracellular channel 1

Network of associatons between targets according to the STRING database.

First level regulatory network of JDP2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
2.3 11.3 GO:0035105 sterol regulatory element binding protein import into nucleus(GO:0035105)
2.0 5.9 GO:0035378 carbon dioxide transmembrane transport(GO:0035378)
1.8 10.9 GO:0015722 canalicular bile acid transport(GO:0015722)
1.2 4.8 GO:0035544 negative regulation of SNARE complex assembly(GO:0035544)
1.2 17.6 GO:0090385 phagosome-lysosome fusion(GO:0090385)
1.1 5.6 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
1.1 4.3 GO:0072334 UDP-galactose transport(GO:0015785) UDP-galactose transmembrane transport(GO:0072334)
1.1 3.2 GO:0060738 intein-mediated protein splicing(GO:0016539) protein splicing(GO:0030908) positive regulation of immature T cell proliferation in thymus(GO:0033092) right lung development(GO:0060458) primary prostatic bud elongation(GO:0060516) epithelial-mesenchymal signaling involved in prostate gland development(GO:0060738)
1.1 18.2 GO:0051599 response to hydrostatic pressure(GO:0051599)
1.0 7.8 GO:1902998 regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
0.9 4.7 GO:0052053 modulation by virus of host molecular function(GO:0039506) suppression by virus of host molecular function(GO:0039507) suppression by virus of host catalytic activity(GO:0039513) modulation by virus of host catalytic activity(GO:0039516) suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process(GO:0039650) negative regulation by symbiont of host catalytic activity(GO:0052053) negative regulation by symbiont of host molecular function(GO:0052056) modulation by symbiont of host catalytic activity(GO:0052148)
0.9 2.8 GO:1903568 negative regulation of protein localization to cilium(GO:1903565) regulation of protein localization to ciliary membrane(GO:1903567) negative regulation of protein localization to ciliary membrane(GO:1903568)
0.9 2.7 GO:0060720 spongiotrophoblast cell proliferation(GO:0060720) regulation of spongiotrophoblast cell proliferation(GO:0060721) cell proliferation involved in embryonic placenta development(GO:0060722) regulation of cell proliferation involved in embryonic placenta development(GO:0060723)
0.8 12.4 GO:0070307 lens fiber cell development(GO:0070307)
0.8 10.0 GO:0061087 positive regulation of histone H3-K27 methylation(GO:0061087)
0.7 7.4 GO:2000189 positive regulation of cholesterol homeostasis(GO:2000189)
0.7 6.2 GO:1902748 positive regulation of lens fiber cell differentiation(GO:1902748)
0.7 6.6 GO:0045218 zonula adherens maintenance(GO:0045218)
0.5 11.2 GO:0070493 thrombin receptor signaling pathway(GO:0070493)
0.5 4.2 GO:1903976 negative regulation of glial cell migration(GO:1903976)
0.5 10.8 GO:0044849 estrous cycle(GO:0044849)
0.5 1.4 GO:0070676 intralumenal vesicle formation(GO:0070676)
0.4 9.8 GO:1904714 regulation of chaperone-mediated autophagy(GO:1904714)
0.4 4.2 GO:0071638 negative regulation of monocyte chemotactic protein-1 production(GO:0071638)
0.4 1.1 GO:0045907 positive regulation of vasoconstriction(GO:0045907)
0.4 1.4 GO:0002268 follicular dendritic cell differentiation(GO:0002268)
0.3 3.0 GO:0051344 regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051342) negative regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051344)
0.3 1.2 GO:1902031 regulation of NADP metabolic process(GO:1902031)
0.3 2.7 GO:0002036 regulation of L-glutamate transport(GO:0002036)
0.3 3.6 GO:0014722 regulation of skeletal muscle contraction by calcium ion signaling(GO:0014722)
0.2 1.0 GO:0052229 multi-organism catabolic process(GO:0044035) development of symbiont involved in interaction with host(GO:0044115) modulation of development of symbiont involved in interaction with host(GO:0044145) negative regulation of development of symbiont involved in interaction with host(GO:0044147) metabolism of substance in other organism involved in symbiotic interaction(GO:0052214) catabolism of substance in other organism involved in symbiotic interaction(GO:0052227) metabolism of macromolecule in other organism involved in symbiotic interaction(GO:0052229) catabolism by host of symbiont macromolecule(GO:0052360) catabolism by organism of macromolecule in other organism involved in symbiotic interaction(GO:0052361) catabolism by host of symbiont protein(GO:0052362) catabolism by organism of protein in other organism involved in symbiotic interaction(GO:0052363) catabolism by host of substance in symbiont(GO:0052364) metabolism by host of symbiont macromolecule(GO:0052416) metabolism by host of symbiont protein(GO:0052417) metabolism by organism of protein in other organism involved in symbiotic interaction(GO:0052418) metabolism by host of substance in symbiont(GO:0052419)
0.2 7.3 GO:0032354 response to follicle-stimulating hormone(GO:0032354)
0.2 1.8 GO:0040034 regulation of development, heterochronic(GO:0040034) regulation of timing of cell differentiation(GO:0048505)
0.2 2.2 GO:0034036 purine ribonucleoside bisphosphate biosynthetic process(GO:0034036) 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process(GO:0050428)
0.2 2.6 GO:0070836 caveola assembly(GO:0070836)
0.2 13.7 GO:0061718 NADH regeneration(GO:0006735) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.2 1.2 GO:0000720 pyrimidine dimer repair by nucleotide-excision repair(GO:0000720)
0.2 0.8 GO:1990502 dense core granule maturation(GO:1990502)
0.2 0.6 GO:1904428 negative regulation of tubulin deacetylation(GO:1904428)
0.2 9.5 GO:0008045 motor neuron axon guidance(GO:0008045)
0.2 1.7 GO:0060012 synaptic transmission, glycinergic(GO:0060012)
0.2 3.4 GO:0070166 enamel mineralization(GO:0070166)
0.2 3.1 GO:0045793 positive regulation of cell size(GO:0045793)
0.2 2.1 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.2 0.5 GO:1904924 negative regulation of mitophagy in response to mitochondrial depolarization(GO:1904924)
0.2 3.4 GO:1903830 magnesium ion transmembrane transport(GO:1903830)
0.2 2.7 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.1 7.0 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.1 0.7 GO:1903422 negative regulation of synaptic vesicle recycling(GO:1903422)
0.1 4.3 GO:0030728 ovulation(GO:0030728)
0.1 6.3 GO:0019430 removal of superoxide radicals(GO:0019430)
0.1 8.0 GO:0006298 mismatch repair(GO:0006298)
0.1 1.9 GO:0048245 eosinophil chemotaxis(GO:0048245)
0.1 1.6 GO:0060842 arterial endothelial cell differentiation(GO:0060842)
0.1 1.5 GO:0044130 negative regulation of growth of symbiont in host(GO:0044130)
0.1 0.9 GO:0098989 NMDA selective glutamate receptor signaling pathway(GO:0098989)
0.1 0.6 GO:0036414 protein citrullination(GO:0018101) histone citrullination(GO:0036414)
0.1 2.2 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.1 0.6 GO:0021633 optic nerve structural organization(GO:0021633)
0.1 1.0 GO:2000389 regulation of neutrophil extravasation(GO:2000389)
0.1 7.3 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.1 1.0 GO:0044821 meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
0.1 2.0 GO:0045779 negative regulation of bone resorption(GO:0045779)
0.1 2.1 GO:0071361 cellular response to ethanol(GO:0071361)
0.1 1.2 GO:0042354 fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355)
0.1 0.8 GO:0035249 synaptic transmission, glutamatergic(GO:0035249)
0.1 0.2 GO:0030264 nuclear fragmentation involved in apoptotic nuclear change(GO:0030264)
0.1 1.9 GO:0034030 coenzyme A biosynthetic process(GO:0015937) nucleoside bisphosphate biosynthetic process(GO:0033866) ribonucleoside bisphosphate biosynthetic process(GO:0034030) purine nucleoside bisphosphate biosynthetic process(GO:0034033)
0.1 1.0 GO:0034134 toll-like receptor 2 signaling pathway(GO:0034134)
0.1 0.6 GO:0045625 regulation of T-helper 1 cell differentiation(GO:0045625)
0.1 1.1 GO:0015886 heme transport(GO:0015886)
0.1 3.9 GO:0048286 lung alveolus development(GO:0048286)
0.1 1.2 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.1 0.6 GO:0046813 receptor-mediated virion attachment to host cell(GO:0046813)
0.0 1.3 GO:0019722 calcium-mediated signaling(GO:0019722)
0.0 1.2 GO:0045109 intermediate filament organization(GO:0045109)
0.0 0.2 GO:0009257 10-formyltetrahydrofolate biosynthetic process(GO:0009257)
0.0 0.3 GO:1903385 regulation of homophilic cell adhesion(GO:1903385)
0.0 0.9 GO:1903543 positive regulation of exosomal secretion(GO:1903543)
0.0 0.7 GO:1990182 exosomal secretion(GO:1990182)
0.0 1.9 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026)
0.0 4.1 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.0 3.3 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.0 1.0 GO:0035729 cellular response to hepatocyte growth factor stimulus(GO:0035729)
0.0 1.2 GO:0055003 cardiac myofibril assembly(GO:0055003)
0.0 2.6 GO:0002756 MyD88-independent toll-like receptor signaling pathway(GO:0002756)
0.0 0.3 GO:0061368 negative regulation of growth hormone secretion(GO:0060125) behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
0.0 0.2 GO:0044245 polysaccharide digestion(GO:0044245)
0.0 0.6 GO:0051964 negative regulation of synapse assembly(GO:0051964)
0.0 0.6 GO:0043248 proteasome assembly(GO:0043248)
0.0 0.3 GO:0009253 peptidoglycan metabolic process(GO:0000270) peptidoglycan catabolic process(GO:0009253)
0.0 1.7 GO:0097120 receptor localization to synapse(GO:0097120)
0.0 1.1 GO:0021952 central nervous system projection neuron axonogenesis(GO:0021952)
0.0 1.4 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.0 1.2 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.0 0.9 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.0 0.6 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024)
0.0 0.2 GO:0072734 response to staurosporine(GO:0072733) cellular response to staurosporine(GO:0072734)
0.0 2.3 GO:0030239 myofibril assembly(GO:0030239)
0.0 4.3 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.7 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.0 0.6 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 2.3 GO:1903955 positive regulation of protein targeting to mitochondrion(GO:1903955)
0.0 0.5 GO:0008277 regulation of G-protein coupled receptor protein signaling pathway(GO:0008277)
0.0 0.2 GO:0060539 diaphragm development(GO:0060539)
0.0 0.3 GO:0040020 regulation of meiotic nuclear division(GO:0040020)
0.0 0.6 GO:0006308 DNA catabolic process(GO:0006308)
0.0 1.4 GO:0032147 activation of protein kinase activity(GO:0032147)
0.0 0.5 GO:0048873 homeostasis of number of cells within a tissue(GO:0048873)
0.0 0.5 GO:0030318 melanocyte differentiation(GO:0030318)
0.0 1.9 GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436)
0.0 0.8 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.9 GO:0042267 natural killer cell mediated cytotoxicity(GO:0042267)
0.0 1.0 GO:0007602 phototransduction(GO:0007602)
0.0 0.5 GO:0031424 keratinization(GO:0031424)
0.0 1.9 GO:0007098 centrosome cycle(GO:0007098)
0.0 0.9 GO:0045670 regulation of osteoclast differentiation(GO:0045670)
0.0 7.5 GO:0043687 post-translational protein modification(GO:0043687)
0.0 1.7 GO:0051781 positive regulation of cell division(GO:0051781)
0.0 1.5 GO:0034968 histone lysine methylation(GO:0034968)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
2.0 5.9 GO:0020003 symbiont-containing vacuole(GO:0020003) symbiont-containing vacuole membrane(GO:0020005)
1.5 13.4 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
1.1 11.3 GO:0005638 lamin filament(GO:0005638)
0.7 9.5 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.5 7.8 GO:0034366 spherical high-density lipoprotein particle(GO:0034366)
0.4 18.2 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.4 3.6 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)
0.4 1.5 GO:0044753 amphisome(GO:0044753)
0.4 3.0 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.4 1.4 GO:0033257 Bcl3/NF-kappaB2 complex(GO:0033257)
0.3 6.6 GO:0005915 zonula adherens(GO:0005915)
0.2 10.0 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.2 1.0 GO:1990667 PCSK9-AnxA2 complex(GO:1990667)
0.2 4.7 GO:0031265 CD95 death-inducing signaling complex(GO:0031265) ripoptosome(GO:0097342)
0.2 1.2 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110)
0.2 1.0 GO:0045323 interleukin-1 receptor complex(GO:0045323)
0.2 18.7 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.1 1.9 GO:0070652 HAUS complex(GO:0070652)
0.1 0.9 GO:0033565 ESCRT-0 complex(GO:0033565)
0.1 18.3 GO:0005882 intermediate filament(GO:0005882)
0.1 3.6 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.1 2.1 GO:0008385 IkappaB kinase complex(GO:0008385)
0.1 3.3 GO:0000145 exocyst(GO:0000145)
0.1 0.7 GO:0044294 dendritic growth cone(GO:0044294)
0.1 2.0 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.1 3.4 GO:0071339 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.1 0.3 GO:0030934 anchoring collagen complex(GO:0030934)
0.1 6.2 GO:1904724 tertiary granule lumen(GO:1904724)
0.1 5.6 GO:0015030 Cajal body(GO:0015030)
0.1 1.5 GO:0031045 dense core granule(GO:0031045)
0.1 4.3 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.1 0.6 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 1.4 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 1.0 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 1.5 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.0 1.4 GO:0008305 integrin complex(GO:0008305)
0.0 1.0 GO:0031143 pseudopodium(GO:0031143)
0.0 0.5 GO:0035631 CD40 receptor complex(GO:0035631)
0.0 2.6 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 1.3 GO:0005719 nuclear euchromatin(GO:0005719)
0.0 3.8 GO:0044291 cell-cell contact zone(GO:0044291)
0.0 0.7 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0 0.4 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
0.0 1.1 GO:0031430 M band(GO:0031430)
0.0 2.3 GO:0101003 ficolin-1-rich granule membrane(GO:0101003)
0.0 7.4 GO:0036464 cytoplasmic ribonucleoprotein granule(GO:0036464)
0.0 0.2 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.0 4.9 GO:0008021 synaptic vesicle(GO:0008021)
0.0 3.2 GO:0030018 Z disc(GO:0030018)
0.0 0.8 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 1.2 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 1.0 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.2 GO:0035686 sperm fibrous sheath(GO:0035686)
0.0 6.5 GO:0005925 focal adhesion(GO:0005925)
0.0 1.3 GO:0005913 cell-cell adherens junction(GO:0005913)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
3.6 10.9 GO:0015432 bile acid-exporting ATPase activity(GO:0015432)
2.1 6.3 GO:0003955 NAD(P)H dehydrogenase (quinone) activity(GO:0003955)
2.0 5.9 GO:0035379 carbon dioxide transmembrane transporter activity(GO:0035379)
1.9 5.6 GO:0008859 exoribonuclease II activity(GO:0008859)
1.6 11.2 GO:0015057 thrombin receptor activity(GO:0015057)
1.5 13.4 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
1.3 8.0 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
1.1 4.3 GO:0005459 UDP-galactose transmembrane transporter activity(GO:0005459)
0.9 6.3 GO:1990254 keratin filament binding(GO:1990254)
0.7 4.7 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.6 1.9 GO:0004794 L-threonine ammonia-lyase activity(GO:0004794)
0.6 1.8 GO:0047389 glycerophosphocholine phosphodiesterase activity(GO:0047389)
0.6 17.6 GO:0017160 Ral GTPase binding(GO:0017160)
0.4 3.6 GO:0016728 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.4 2.1 GO:1990450 linear polyubiquitin binding(GO:1990450)
0.4 1.7 GO:0015375 glycine:sodium symporter activity(GO:0015375)
0.4 2.1 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
0.4 3.2 GO:0043237 laminin-1 binding(GO:0043237)
0.3 1.3 GO:1902122 chenodeoxycholic acid binding(GO:1902122)
0.3 1.2 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.3 1.1 GO:0031728 CCR3 chemokine receptor binding(GO:0031728)
0.3 6.1 GO:0005212 structural constituent of eye lens(GO:0005212)
0.3 9.5 GO:0003746 translation elongation factor activity(GO:0003746)
0.3 3.6 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.2 7.8 GO:0051787 misfolded protein binding(GO:0051787)
0.2 1.3 GO:0051373 FATZ binding(GO:0051373)
0.2 6.6 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.2 1.2 GO:0017060 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity(GO:0017060)
0.2 2.3 GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.2 1.2 GO:0004471 malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473)
0.2 3.0 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.2 18.2 GO:0097110 scaffold protein binding(GO:0097110)
0.2 9.5 GO:0046875 ephrin receptor binding(GO:0046875)
0.2 0.9 GO:0047685 amine sulfotransferase activity(GO:0047685)
0.2 1.2 GO:1990599 3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599)
0.1 1.0 GO:0003924 GTPase activity(GO:0003924)
0.1 0.6 GO:0004530 deoxyribonuclease I activity(GO:0004530)
0.1 0.6 GO:0034618 arginine binding(GO:0034618)
0.1 3.4 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.1 1.2 GO:0030023 extracellular matrix constituent conferring elasticity(GO:0030023)
0.1 7.3 GO:0005504 fatty acid binding(GO:0005504)
0.1 2.2 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.1 4.3 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 1.0 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.1 0.6 GO:0001602 pancreatic polypeptide receptor activity(GO:0001602)
0.1 10.0 GO:0035064 methylated histone binding(GO:0035064)
0.1 1.0 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.1 6.2 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.1 0.2 GO:0017082 mineralocorticoid receptor activity(GO:0017082)
0.1 2.6 GO:0070300 phosphatidic acid binding(GO:0070300)
0.1 0.7 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.1 7.3 GO:0004004 ATP-dependent RNA helicase activity(GO:0004004)
0.1 1.0 GO:0043495 protein anchor(GO:0043495)
0.1 2.7 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.1 1.1 GO:0015232 heme transporter activity(GO:0015232)
0.1 0.7 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.1 5.2 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.1 0.2 GO:0004618 phosphoglycerate kinase activity(GO:0004618)
0.1 0.7 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.1 1.8 GO:0031489 myosin V binding(GO:0031489)
0.1 1.4 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.0 1.4 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 0.2 GO:0004329 formate-tetrahydrofolate ligase activity(GO:0004329)
0.0 1.2 GO:0031005 filamin binding(GO:0031005)
0.0 1.2 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 1.0 GO:0071837 HMG box domain binding(GO:0071837)
0.0 5.0 GO:0005179 hormone activity(GO:0005179)
0.0 2.1 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.4 GO:0004969 histamine receptor activity(GO:0004969)
0.0 0.6 GO:0008432 JUN kinase binding(GO:0008432)
0.0 1.0 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 0.6 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.0 1.7 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 5.3 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 1.9 GO:0016831 carboxy-lyase activity(GO:0016831)
0.0 0.3 GO:0008097 5S rRNA binding(GO:0008097)
0.0 0.8 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 2.0 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 1.4 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.0 0.9 GO:0042288 MHC class I protein binding(GO:0042288)
0.0 1.1 GO:0005516 calmodulin binding(GO:0005516)
0.0 0.3 GO:0003796 lysozyme activity(GO:0003796)
0.0 0.5 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 3.6 GO:0031072 heat shock protein binding(GO:0031072)
0.0 0.6 GO:0071617 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841) lysophosphatidic acid acyltransferase activity(GO:0042171) lysophospholipid acyltransferase activity(GO:0071617)
0.0 0.2 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 1.7 GO:0032947 protein complex scaffold(GO:0032947)
0.0 3.6 GO:0000149 SNARE binding(GO:0000149)
0.0 0.7 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 12.3 GO:0004674 protein serine/threonine kinase activity(GO:0004674)
0.0 1.5 GO:0051219 phosphoprotein binding(GO:0051219)
0.0 0.9 GO:0031593 polyubiquitin binding(GO:0031593)
0.0 0.2 GO:0004568 chitinase activity(GO:0004568)
0.0 0.3 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.8 GO:0030507 spectrin binding(GO:0030507)
0.0 2.2 GO:0017124 SH3 domain binding(GO:0017124)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 11.2 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.2 18.1 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.1 3.1 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.1 6.5 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.1 8.3 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.1 13.3 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.1 7.4 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.1 10.0 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.1 3.2 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.1 5.9 PID AURORA B PATHWAY Aurora B signaling
0.1 3.8 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.1 3.6 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.1 8.1 PID E2F PATHWAY E2F transcription factor network
0.1 1.4 PID LPA4 PATHWAY LPA4-mediated signaling events
0.1 3.3 PID INSULIN PATHWAY Insulin Pathway
0.1 7.8 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.1 4.2 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 1.7 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.0 3.6 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 2.6 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.0 2.8 PID IL4 2PATHWAY IL4-mediated signaling events
0.0 1.0 PID CONE PATHWAY Visual signal transduction: Cones
0.0 0.6 PID IL27 PATHWAY IL27-mediated signaling events
0.0 1.2 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 1.3 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 1.1 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 8.8 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 0.3 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 1.4 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 1.2 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.0 0.5 PID LYSOPHOSPHOLIPID PATHWAY LPA receptor mediated events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 10.9 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.4 5.9 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.3 6.8 REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.2 10.5 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.2 10.1 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.2 5.9 REACTOME EXTRACELLULAR MATRIX ORGANIZATION Genes involved in Extracellular matrix organization
0.2 13.7 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.2 12.2 REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.2 6.5 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.2 2.5 REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES Genes involved in p75NTR recruits signalling complexes
0.1 12.2 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.1 3.6 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.1 2.7 REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.1 4.4 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.1 3.3 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.1 1.9 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.1 6.9 REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.1 1.4 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.1 1.4 REACTOME TRAF6 MEDIATED NFKB ACTIVATION Genes involved in TRAF6 mediated NF-kB activation
0.1 1.7 REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
0.1 1.7 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.1 0.8 REACTOME SHC MEDIATED SIGNALLING Genes involved in SHC-mediated signalling
0.1 3.1 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 7.8 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 2.2 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0 3.7 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 1.7 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 1.2 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER
0.0 1.5 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 2.6 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 8.5 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 3.2 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.6 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.0 0.9 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 3.6 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 1.2 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.0 0.9 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 1.2 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 0.4 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.0 1.0 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.3 REACTOME NUCLEAR SIGNALING BY ERBB4 Genes involved in Nuclear signaling by ERBB4