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SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for JUND

Z-value: 1.13

Motif logo

Transcription factors associated with JUND

Gene Symbol Gene ID Gene Info
ENSG00000130522.4 JunD proto-oncogene, AP-1 transcription factor subunit

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
JUNDhg19_v2_chr19_-_18391708_183917390.921.2e-08Click!

Activity profile of JUND motif

Sorted Z-values of JUND motif

Promoter Log-likelihood Transcript Gene Gene Info
chr21_-_43786634 5.80 ENST00000291527.2
trefoil factor 1
chr17_+_25799008 4.84 ENST00000583370.1
ENST00000398988.3
ENST00000268763.6
kinase suppressor of ras 1
chr16_+_57844549 4.71 ENST00000564282.1
uncharacterized protein LOC388282
chr12_+_52695617 4.37 ENST00000293525.5
keratin 86
chr20_-_62129163 4.35 ENST00000298049.7
eukaryotic translation elongation factor 1 alpha 2
chr11_+_67250490 3.41 ENST00000528641.2
ENST00000279146.3
aryl hydrocarbon receptor interacting protein
chr8_-_27472198 3.31 ENST00000519472.1
ENST00000523589.1
ENST00000522413.1
ENST00000523396.1
ENST00000560366.1
clusterin
chr4_-_89079817 3.17 ENST00000505480.1
ATP-binding cassette, sub-family G (WHITE), member 2
chr10_+_17270214 3.07 ENST00000544301.1
vimentin
chr15_+_59903975 3.00 ENST00000560585.1
ENST00000396065.1
glucosaminyl (N-acetyl) transferase 3, mucin type
chr5_-_140013275 2.87 ENST00000512545.1
ENST00000302014.6
ENST00000401743.2
CD14 molecule
chr7_-_33080506 2.74 ENST00000381626.2
ENST00000409467.1
ENST00000449201.1
5'-nucleotidase, cytosolic IIIA
chr8_-_17752996 2.70 ENST00000381841.2
ENST00000427924.1
fibrinogen-like 1
chr10_+_5005598 2.68 ENST00000442997.1
aldo-keto reductase family 1, member C1
chr16_-_30997533 2.62 ENST00000602217.1
Uncharacterized protein
chr8_-_17752912 2.62 ENST00000398054.1
ENST00000381840.2
fibrinogen-like 1
chr12_-_102591604 2.59 ENST00000329406.4
pro-melanin-concentrating hormone
chr15_-_74504560 2.56 ENST00000449139.2
stimulated by retinoic acid 6
chr15_-_74504597 2.56 ENST00000416286.3
stimulated by retinoic acid 6
chrY_+_15016725 2.52 ENST00000336079.3
DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
chr12_-_53343602 2.45 ENST00000546897.1
ENST00000552551.1
keratin 8
chr16_+_19467772 2.42 ENST00000219821.5
ENST00000561503.1
ENST00000564959.1
transmembrane channel-like 5
chr19_-_46285646 2.18 ENST00000458663.2
dystrophia myotonica-protein kinase
chr12_-_53297432 2.06 ENST00000546900.1
keratin 8
chr12_-_53343633 2.06 ENST00000546826.1
keratin 8
chr20_-_33460621 2.04 ENST00000427420.1
ENST00000336431.5
gamma-glutamyltransferase 7
chr12_-_15815626 2.03 ENST00000540613.1
epidermal growth factor receptor pathway substrate 8
chr20_-_17539456 2.03 ENST00000544874.1
ENST00000377868.2
beaded filament structural protein 1, filensin
chr1_-_153521597 1.86 ENST00000368712.1
S100 calcium binding protein A3
chr17_-_33390667 1.82 ENST00000378516.2
ENST00000268850.7
ENST00000394597.2
ring finger and FYVE-like domain containing E3 ubiquitin protein ligase
chr5_-_140013224 1.80 ENST00000498971.2
CD14 molecule
chr16_+_15596123 1.79 ENST00000452191.2
chromosome 16 open reading frame 45
chr17_+_7590734 1.67 ENST00000457584.2
WD repeat containing, antisense to TP53
chr19_-_46285736 1.63 ENST00000291270.4
ENST00000447742.2
ENST00000354227.5
dystrophia myotonica-protein kinase
chr12_-_112443830 1.60 ENST00000550037.1
ENST00000549425.1
transmembrane protein 116
chr3_+_98699880 1.58 ENST00000473756.1
long intergenic non-protein coding RNA 973
chr12_+_7023491 1.51 ENST00000541477.1
ENST00000229277.1
enolase 2 (gamma, neuronal)
chr18_-_19283649 1.48 ENST00000584464.1
ENST00000578270.1
abhydrolase domain containing 3
chr12_-_120241187 1.48 ENST00000392520.2
citron (rho-interacting, serine/threonine kinase 21)
chr1_-_153521714 1.47 ENST00000368713.3
S100 calcium binding protein A3
chr1_-_153935791 1.46 ENST00000429040.1
solute carrier family 39 (zinc transporter), member 1
chr14_-_23426337 1.43 ENST00000342454.8
ENST00000555986.1
ENST00000541587.1
ENST00000554516.1
ENST00000347758.2
ENST00000206474.7
ENST00000555040.1
HAUS augmin-like complex, subunit 4
chr14_-_23426270 1.38 ENST00000557591.1
ENST00000397409.4
ENST00000490506.1
ENST00000554406.1
HAUS augmin-like complex, subunit 4
chr17_+_76311791 1.35 ENST00000586321.1
AC061992.2
chr14_-_23426231 1.34 ENST00000556915.1
HAUS augmin-like complex, subunit 4
chr14_+_32476072 1.28 ENST00000556949.1
Uncharacterized protein
chr12_-_112443767 1.28 ENST00000550233.1
ENST00000546962.1
ENST00000550800.2
transmembrane protein 116
chr1_-_153513170 1.27 ENST00000368717.2
S100 calcium binding protein A5
chr11_-_4719072 1.20 ENST00000396950.3
ENST00000532598.1
olfactory receptor, family 51, subfamily E, member 2
chr1_-_153935738 1.19 ENST00000417348.1
solute carrier family 39 (zinc transporter), member 1
chr17_-_54893250 1.18 ENST00000397862.2
chromosome 17 open reading frame 67
chr2_+_27505260 1.17 ENST00000380075.2
ENST00000296098.4
tripartite motif containing 54
chr1_-_54637997 1.16 ENST00000536061.1
CDNA: FLJ21031 fis, clone CAE07336; HCG1780521; Uncharacterized protein
chr20_+_48429356 1.14 ENST00000361573.2
ENST00000541138.1
ENST00000539601.1
solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
chr9_-_39239171 1.13 ENST00000358144.2
contactin associated protein-like 3
chr6_+_159291090 1.13 ENST00000367073.4
ENST00000608817.1
chromosome 6 open reading frame 99
chr16_-_67281413 1.13 ENST00000258201.4
formin homology 2 domain containing 1
chr13_-_30160925 1.12 ENST00000450494.1
solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
chr2_-_145275109 1.12 ENST00000431672.2
zinc finger E-box binding homeobox 2
chrX_-_154493791 1.11 ENST00000369454.3
RAB39B, member RAS oncogene family
chr15_-_59949693 1.09 ENST00000396063.1
ENST00000396064.3
ENST00000484743.1
ENST00000559706.1
ENST00000396060.2
general transcription factor IIA, 2, 12kDa
chr16_+_31366536 1.08 ENST00000562522.1
integrin, alpha X (complement component 3 receptor 4 subunit)
chr6_+_44194762 1.07 ENST00000371708.1
solute carrier family 29 (equilibrative nucleoside transporter), member 1
chr14_-_23426322 1.07 ENST00000555367.1
HAUS augmin-like complex, subunit 4
chr19_+_13842559 1.06 ENST00000586600.1
coiled-coil domain containing 130
chr10_-_128210005 1.05 ENST00000284694.7
ENST00000454341.1
ENST00000432642.1
ENST00000392694.1
chromosome 10 open reading frame 90
chr1_-_11918988 1.00 ENST00000376468.3
natriuretic peptide B
chr5_-_140013241 0.97 ENST00000519715.1
CD14 molecule
chr15_+_89182156 0.96 ENST00000379224.5
interferon stimulated exonuclease gene 20kDa
chr5_+_169758393 0.95 ENST00000521471.1
ENST00000518357.1
ENST00000436248.3
CTB-114C7.3
chr20_+_48429233 0.93 ENST00000417961.1
solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
chr16_+_31366455 0.92 ENST00000268296.4
integrin, alpha X (complement component 3 receptor 4 subunit)
chr17_+_1936687 0.91 ENST00000570477.1
diphthamide biosynthesis 1
chr5_+_147582387 0.88 ENST00000325630.2
serine peptidase inhibitor, Kazal type 6
chr12_-_8765446 0.87 ENST00000537228.1
ENST00000229335.6
activation-induced cytidine deaminase
chr17_-_70417365 0.87 ENST00000580948.1
long intergenic non-protein coding RNA 511
chr17_-_7590745 0.87 ENST00000514944.1
ENST00000503591.1
ENST00000455263.2
ENST00000420246.2
ENST00000445888.2
ENST00000509690.1
ENST00000604348.1
ENST00000269305.4
tumor protein p53
chr19_-_56047661 0.86 ENST00000344158.3
SH3 domain binding kinase family, member 2
chr22_+_42475692 0.85 ENST00000331479.3
single-pass membrane protein with aspartate-rich tail 1
chr19_-_44008863 0.85 ENST00000601646.1
pleckstrin homology-like domain, family B, member 3
chr14_+_73525265 0.83 ENST00000525161.1
RNA binding motif protein 25
chr15_+_89182178 0.82 ENST00000559876.1
interferon stimulated exonuclease gene 20kDa
chr7_+_130126165 0.82 ENST00000427521.1
ENST00000416162.2
ENST00000378576.4
mesoderm specific transcript
chr19_-_35981358 0.82 ENST00000484218.2
ENST00000338897.3
keratinocyte differentiation-associated protein
chr1_-_219615984 0.81 ENST00000420762.1
RP11-95P13.1
chr13_-_31038370 0.81 ENST00000399489.1
ENST00000339872.4
high mobility group box 1
chr3_-_145940126 0.81 ENST00000498625.1
phospholipid scramblase 4
chr3_+_158991025 0.80 ENST00000337808.6
IQCJ-SCHIP1 readthrough
chr4_-_104119528 0.80 ENST00000380026.3
ENST00000503705.1
ENST00000265148.3
centromere protein E, 312kDa
chr5_+_140227048 0.78 ENST00000532602.1
protocadherin alpha 9
chr21_-_35340759 0.77 ENST00000607953.1
AP000569.9
chr6_+_32146268 0.77 ENST00000427134.2
ring finger protein 5, E3 ubiquitin protein ligase
chr12_-_74796291 0.77 ENST00000551726.1
RP11-81H3.2
chr1_+_159796534 0.77 ENST00000289707.5
SLAM family member 8
chr15_-_50838888 0.76 ENST00000532404.1
ubiquitin specific peptidase 50
chr15_+_89181974 0.74 ENST00000306072.5
interferon stimulated exonuclease gene 20kDa
chr16_+_85936295 0.73 ENST00000563180.1
ENST00000564617.1
ENST00000564803.1
interferon regulatory factor 8
chr4_-_123542224 0.72 ENST00000264497.3
interleukin 21
chr5_-_60140089 0.72 ENST00000507047.1
ENST00000438340.1
ENST00000425382.1
ENST00000508821.1
ELOVL fatty acid elongase 7
chr10_-_75008620 0.71 ENST00000372950.4
DnaJ (Hsp40) homolog, subfamily C, member 9
chr17_+_12859080 0.70 ENST00000583608.1
Rho GTPase activating protein 44
chr11_-_14913190 0.69 ENST00000532378.1
cytochrome P450, family 2, subfamily R, polypeptide 1
chr5_+_147582348 0.69 ENST00000514389.1
serine peptidase inhibitor, Kazal type 6
chr19_+_35820064 0.68 ENST00000341773.6
ENST00000600131.1
ENST00000270311.6
ENST00000595780.1
ENST00000597916.1
ENST00000593867.1
ENST00000600424.1
ENST00000599811.1
ENST00000536635.2
ENST00000085219.5
ENST00000544992.2
ENST00000419549.2
CD22 molecule
chr22_-_43398442 0.65 ENST00000422336.1
protein kinase C and casein kinase substrate in neurons 2
chr15_+_75335604 0.63 ENST00000563393.1
phosphopantothenoylcysteine decarboxylase
chr13_+_98605902 0.63 ENST00000460070.1
ENST00000481455.1
ENST00000261574.5
ENST00000493281.1
ENST00000463157.1
ENST00000471898.1
ENST00000489058.1
ENST00000481689.1
importin 5
chr5_+_38148582 0.61 ENST00000508853.1
CTD-2207A17.1
chr10_+_49892904 0.60 ENST00000360890.2
WDFY family member 4
chr5_-_60140009 0.60 ENST00000505959.1
ELOVL fatty acid elongase 7
chr3_-_122512619 0.60 ENST00000383659.1
ENST00000306103.2
HSPB (heat shock 27kDa) associated protein 1
chr19_+_38880695 0.59 ENST00000587947.1
ENST00000338502.4
sprouty-related, EVH1 domain containing 3
chr2_+_161993465 0.58 ENST00000457476.1
TRAF family member-associated NFKB activator
chr1_-_235116495 0.58 ENST00000549744.1
RP11-443B7.3
chr3_-_155011483 0.58 ENST00000489090.1
RP11-451G4.2
chr2_-_145275211 0.57 ENST00000462355.1
zinc finger E-box binding homeobox 2
chr17_-_39156138 0.55 ENST00000391587.1
keratin associated protein 3-2
chr16_-_75301886 0.55 ENST00000393422.2
breast cancer anti-estrogen resistance 1
chr6_+_63921351 0.55 ENST00000370659.1
FK506 binding protein 1C
chr21_+_30672433 0.55 ENST00000451655.1
BTB and CNC homology 1, basic leucine zipper transcription factor 1
chr2_+_36923830 0.54 ENST00000379242.3
ENST00000389975.3
vitrin
chr2_+_102615416 0.52 ENST00000393414.2
interleukin 1 receptor, type II
chr12_+_9142131 0.51 ENST00000356986.3
ENST00000266551.4
killer cell lectin-like receptor subfamily G, member 1
chr19_-_11545920 0.51 ENST00000356392.4
ENST00000591179.1
coiled-coil domain containing 151
chr10_-_31288398 0.51 ENST00000538351.2
zinc finger protein 438
chr8_+_70476088 0.50 ENST00000525999.1
sulfatase 1
chr10_-_27529486 0.49 ENST00000375888.1
acyl-CoA binding domain containing 5
chr17_-_38928414 0.49 ENST00000335552.4
keratin 26
chr6_+_159290917 0.48 ENST00000367072.1
chromosome 6 open reading frame 99
chr10_+_18549645 0.48 ENST00000396576.2
calcium channel, voltage-dependent, beta 2 subunit
chrX_-_153718953 0.47 ENST00000369649.4
ENST00000393586.1
solute carrier family 10, member 3
chrX_+_154254960 0.47 ENST00000369498.3
FUN14 domain containing 2
chr1_+_41204506 0.46 ENST00000525290.1
ENST00000530965.1
ENST00000416859.2
ENST00000308733.5
nuclear transcription factor Y, gamma
chr20_-_36794902 0.46 ENST00000373403.3
transglutaminase 2
chr19_+_35810164 0.44 ENST00000598537.1
CD22 molecule
chr17_-_25568687 0.44 ENST00000581944.1
RP11-663N22.1
chr1_-_223853425 0.42 ENST00000366873.2
ENST00000419193.2
calpain 8
chr1_+_207262881 0.41 ENST00000451804.2
complement component 4 binding protein, beta
chrX_-_51797351 0.41 ENST00000375644.3
RP11-114H20.1
chr3_-_48632593 0.41 ENST00000454817.1
ENST00000328333.8
collagen, type VII, alpha 1
chr5_+_35852797 0.41 ENST00000508941.1
interleukin 7 receptor
chr2_+_68872954 0.38 ENST00000394342.2
prokineticin receptor 1
chr2_-_231789941 0.38 ENST00000392040.1
ENST00000438398.1
G protein-coupled receptor 55
chr10_-_74114714 0.37 ENST00000338820.3
ENST00000394903.2
ENST00000444643.2
DnaJ (Hsp40) homolog, subfamily B, member 12
chr7_+_33765593 0.37 ENST00000311067.3
HCG1643653; Uncharacterized protein
chr11_-_6008215 0.34 ENST00000332249.4
olfactory receptor, family 52, subfamily L, member 1
chr16_-_72206034 0.33 ENST00000537465.1
ENST00000237353.10
polyamine modulated factor 1 binding protein 1
chr12_-_122710514 0.33 ENST00000540535.1
ENST00000541656.1
diablo, IAP-binding mitochondrial protein
chr17_-_45899126 0.33 ENST00000007414.3
ENST00000392507.3
oxysterol binding protein-like 7
chr8_-_82373809 0.33 ENST00000379071.2
fatty acid binding protein 9, testis
chr4_-_84035905 0.32 ENST00000311507.4
placenta-specific 8
chr3_+_169539710 0.32 ENST00000340806.6
leucine-rich repeats and IQ motif containing 4
chr10_+_69865866 0.31 ENST00000354393.2
myopalladin
chr5_-_135701164 0.30 ENST00000355180.3
ENST00000426057.2
ENST00000513104.1
transient receptor potential cation channel, subfamily C, member 7
chr6_-_44400720 0.30 ENST00000595057.1
AL133262.1
chr2_+_36923901 0.27 ENST00000457137.2
vitrin
chr16_+_28996114 0.25 ENST00000395461.3
linker for activation of T cells
chr3_-_87325728 0.25 ENST00000350375.2
POU class 1 homeobox 1
chrX_-_111923145 0.25 ENST00000371968.3
ENST00000536453.1
lipoma HMGIC fusion partner-like 1
chr1_+_159796589 0.24 ENST00000368104.4
SLAM family member 8
chr16_-_20681177 0.24 ENST00000524149.1
acyl-CoA synthetase medium-chain family member 1
chr15_+_38226827 0.24 ENST00000559502.1
ENST00000558148.1
ENST00000558158.1
transmembrane and coiled-coil domains 5A
chr3_-_150996146 0.23 ENST00000494668.1
purinergic receptor P2Y, G-protein coupled, 14
chr5_-_141061777 0.23 ENST00000239440.4
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
chr18_+_43319467 0.22 ENST00000591541.1
solute carrier family 14 (urea transporter), member 1 (Kidd blood group)
chr15_-_59949667 0.22 ENST00000396061.1
general transcription factor IIA, 2, 12kDa
chr12_-_71182695 0.22 ENST00000342084.4
protein tyrosine phosphatase, receptor type, R
chr3_-_170588163 0.21 ENST00000295830.8
ribosomal protein L22-like 1
chr5_-_96518907 0.20 ENST00000508447.1
ENST00000283109.3
RIO kinase 2
chr3_-_157251383 0.20 ENST00000487753.1
ENST00000489602.1
ENST00000461299.1
ENST00000479987.1
ventricular zone expressed PH domain-containing 1
chr4_+_74576019 0.20 ENST00000436089.1
AC112518.3
chr3_+_156807663 0.20 ENST00000467995.1
ENST00000474477.1
ENST00000471719.1
long intergenic non-protein coding RNA 881
chr10_-_14996321 0.20 ENST00000378289.4
DNA cross-link repair 1C
chr8_-_141774467 0.20 ENST00000520151.1
ENST00000519024.1
ENST00000519465.1
protein tyrosine kinase 2
chr20_-_36794938 0.18 ENST00000453095.1
transglutaminase 2
chr1_-_223853348 0.18 ENST00000366872.5
calpain 8
chr3_+_155860751 0.18 ENST00000471742.1
potassium voltage-gated channel, shaker-related subfamily, beta member 1
chr12_-_27924209 0.18 ENST00000381273.3
MANSC domain containing 4
chr15_-_51535208 0.18 ENST00000405913.3
ENST00000559878.1
cytochrome P450, family 19, subfamily A, polypeptide 1
chr2_+_113670548 0.18 ENST00000263326.3
ENST00000352179.3
ENST00000349806.3
ENST00000353225.3
interleukin 37
chr4_+_95128996 0.18 ENST00000457823.2
SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1
chr10_-_81708854 0.18 ENST00000372292.3
surfactant protein D
chr6_-_43027105 0.17 ENST00000230413.5
ENST00000487429.1
ENST00000489623.1
ENST00000468957.1
mitochondrial ribosomal protein L2
chr6_-_24936170 0.17 ENST00000538035.1
family with sequence similarity 65, member B
chr12_-_58287735 0.16 ENST00000548955.1
RP11-620J15.2
chrX_+_51942963 0.16 ENST00000375625.3
RP11-363G10.2
chr3_-_98241760 0.15 ENST00000507874.1
ENST00000502299.1
ENST00000508659.1
ENST00000510545.1
ENST00000511667.1
ENST00000394185.2
ENST00000394181.2
ENST00000508902.1
ENST00000341181.6
ENST00000437922.1
ENST00000394180.2
claudin domain containing 1
chr12_+_54891495 0.15 ENST00000293373.6
NCK-associated protein 1-like
chr4_-_122085469 0.14 ENST00000057513.3
TNFAIP3 interacting protein 3
chr20_+_30946106 0.13 ENST00000375687.4
ENST00000542461.1
additional sex combs like 1 (Drosophila)
chr7_-_110174754 0.13 ENST00000435466.1
AC003088.1
chr12_+_12938541 0.13 ENST00000356591.4
apolipoprotein L domain containing 1
chr3_+_69811858 0.13 ENST00000433517.1
microphthalmia-associated transcription factor
chr3_-_146213722 0.13 ENST00000336685.2
ENST00000489015.1
phospholipid scramblase 2
chr6_+_151358048 0.12 ENST00000450635.1
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like
chr11_-_18343725 0.12 ENST00000531848.1
Hermansky-Pudlak syndrome 5
chr3_-_42917363 0.12 ENST00000437102.1
cytochrome P450, family 8, subfamily B, polypeptide 1
chr2_-_152830479 0.12 ENST00000360283.6
calcium channel, voltage-dependent, beta 4 subunit
chr1_+_227751231 0.11 ENST00000343776.5
ENST00000608949.1
ENST00000397097.3
zinc finger protein 678
chr1_+_227751281 0.11 ENST00000440339.1
zinc finger protein 678

Network of associatons between targets according to the STRING database.

First level regulatory network of JUND

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 5.1 GO:0061143 alveolar primary septum development(GO:0061143)
0.8 5.6 GO:0071725 toll-like receptor TLR1:TLR2 signaling pathway(GO:0038123) response to triacyl bacterial lipopeptide(GO:0071725) cellular response to triacyl bacterial lipopeptide(GO:0071727)
0.7 3.0 GO:0002426 immunoglobulin production in mucosal tissue(GO:0002426)
0.6 1.7 GO:0032203 telomere formation via telomerase(GO:0032203)
0.5 2.5 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
0.4 3.3 GO:1902998 regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
0.4 6.6 GO:0051599 response to hydrostatic pressure(GO:0051599)
0.4 3.4 GO:0051342 regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051342) negative regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051344)
0.3 2.7 GO:0071395 response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395)
0.3 5.1 GO:0070307 lens fiber cell development(GO:0070307)
0.3 1.8 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.3 2.2 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.3 3.8 GO:0014722 regulation of skeletal muscle contraction by calcium ion signaling(GO:0014722)
0.2 1.8 GO:1903976 negative regulation of glial cell migration(GO:1903976)
0.2 0.9 GO:0051097 negative regulation of helicase activity(GO:0051097) oligodendrocyte apoptotic process(GO:0097252)
0.2 1.1 GO:0015862 uridine transport(GO:0015862)
0.2 0.8 GO:0035711 plasmacytoid dendritic cell activation(GO:0002270) regulation of restriction endodeoxyribonuclease activity(GO:0032072) T-helper 1 cell activation(GO:0035711)
0.2 5.8 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.2 3.2 GO:0042908 xenobiotic transport(GO:0042908)
0.2 4.3 GO:1904714 regulation of chaperone-mediated autophagy(GO:1904714)
0.2 1.7 GO:1902748 positive regulation of lens fiber cell differentiation(GO:1902748)
0.2 1.2 GO:1900133 regulation of renin secretion into blood stream(GO:1900133)
0.2 2.7 GO:0046085 adenosine metabolic process(GO:0046085)
0.1 1.1 GO:1903826 arginine transmembrane transport(GO:1903826)
0.1 0.7 GO:0036378 calcitriol biosynthetic process from calciol(GO:0036378)
0.1 0.5 GO:0050712 negative regulation of interleukin-1 alpha production(GO:0032690) negative regulation of interleukin-1 alpha secretion(GO:0050712)
0.1 0.6 GO:0018262 isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine(GO:0018153) isopeptide cross-linking(GO:0018262)
0.1 0.7 GO:0098886 modification of dendritic spine(GO:0098886)
0.1 0.8 GO:0007079 mitotic chromosome movement towards spindle pole(GO:0007079)
0.1 2.0 GO:1901750 leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750)
0.1 1.3 GO:0034625 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.1 0.5 GO:0000117 regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117)
0.1 2.1 GO:0098719 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.1 0.9 GO:0006216 cytidine catabolic process(GO:0006216) cytidine deamination(GO:0009972) cytidine metabolic process(GO:0046087)
0.1 1.1 GO:0051660 establishment of centrosome localization(GO:0051660)
0.1 0.8 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.1 1.0 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.1 0.9 GO:0017182 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.1 0.2 GO:0018874 benzoate metabolic process(GO:0018874)
0.1 0.5 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.1 0.6 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.1 0.2 GO:0060133 somatotropin secreting cell development(GO:0060133)
0.1 0.5 GO:0098912 membrane depolarization during atrial cardiac muscle cell action potential(GO:0098912) positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.1 0.7 GO:0045078 positive regulation of interferon-gamma biosynthetic process(GO:0045078)
0.1 0.5 GO:0030242 pexophagy(GO:0030242)
0.1 2.7 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.1 0.6 GO:0070836 caveola assembly(GO:0070836)
0.0 4.8 GO:0019933 cAMP-mediated signaling(GO:0019933)
0.0 0.3 GO:0035021 negative regulation of Rac protein signal transduction(GO:0035021)
0.0 0.1 GO:0035359 negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
0.0 0.2 GO:2000863 positive regulation of estrogen secretion(GO:2000863) positive regulation of estradiol secretion(GO:2000866)
0.0 0.8 GO:0007498 mesoderm development(GO:0007498)
0.0 0.6 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 0.4 GO:0030450 regulation of complement activation, classical pathway(GO:0030450) negative regulation of complement activation, classical pathway(GO:0045959)
0.0 0.9 GO:0017121 phospholipid scrambling(GO:0017121)
0.0 0.2 GO:1903385 regulation of homophilic cell adhesion(GO:1903385)
0.0 0.2 GO:2000234 positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
0.0 0.4 GO:0001915 negative regulation of T cell mediated cytotoxicity(GO:0001915)
0.0 2.5 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.0 0.8 GO:0044130 negative regulation of growth of symbiont in host(GO:0044130)
0.0 0.2 GO:0045085 negative regulation of interleukin-2 biosynthetic process(GO:0045085)
0.0 3.0 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.0 0.2 GO:0071918 urea transmembrane transport(GO:0071918)
0.0 0.4 GO:0038171 cannabinoid signaling pathway(GO:0038171)
0.0 5.2 GO:0007098 centrosome cycle(GO:0007098)
0.0 0.6 GO:0071712 ER-associated misfolded protein catabolic process(GO:0071712)
0.0 1.2 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026)
0.0 0.1 GO:0007538 primary sex determination(GO:0007538)
0.0 0.1 GO:0009257 10-formyltetrahydrofolate biosynthetic process(GO:0009257)
0.0 0.4 GO:0071218 cellular response to misfolded protein(GO:0071218)
0.0 1.5 GO:0006735 NADH regeneration(GO:0006735) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.0 0.6 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.0 1.5 GO:0006656 phosphatidylcholine biosynthetic process(GO:0006656)
0.0 1.5 GO:0000281 mitotic cytokinesis(GO:0000281)
0.0 1.3 GO:0051123 RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123)
0.0 0.5 GO:0036158 outer dynein arm assembly(GO:0036158)
0.0 3.0 GO:0070268 cornification(GO:0070268)
0.0 0.3 GO:0001675 acrosome assembly(GO:0001675)
0.0 1.7 GO:0034113 heterotypic cell-cell adhesion(GO:0034113)
0.0 1.1 GO:0010506 regulation of autophagy(GO:0010506)
0.0 0.3 GO:0008635 activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
0.0 0.6 GO:0009615 response to virus(GO:0009615)
0.0 0.3 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.0 0.5 GO:0035729 cellular response to hepatocyte growth factor stimulus(GO:0035729)
0.0 0.3 GO:0006828 manganese ion transport(GO:0006828)
0.0 0.3 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.0 0.2 GO:0038007 netrin-activated signaling pathway(GO:0038007)
0.0 0.2 GO:0060539 diaphragm development(GO:0060539)
0.0 0.3 GO:0071397 cellular response to cholesterol(GO:0071397)
0.0 0.5 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.0 0.6 GO:0031424 keratinization(GO:0031424)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 5.6 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.6 1.8 GO:0002947 tumor necrosis factor receptor superfamily complex(GO:0002947)
0.4 3.4 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.4 5.3 GO:0005577 fibrinogen complex(GO:0005577)
0.4 5.2 GO:0070652 HAUS complex(GO:0070652)
0.3 4.3 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.2 3.3 GO:0034366 spherical high-density lipoprotein particle(GO:0034366)
0.2 1.5 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.2 6.6 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.1 0.8 GO:1990246 uniplex complex(GO:1990246)
0.1 4.3 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.1 1.3 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.1 2.0 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.1 0.4 GO:0030934 anchoring collagen complex(GO:0030934)
0.1 4.9 GO:0045095 keratin filament(GO:0045095)
0.1 1.1 GO:0032059 bleb(GO:0032059)
0.0 4.2 GO:0015030 Cajal body(GO:0015030)
0.0 4.6 GO:0005882 intermediate filament(GO:0005882)
0.0 0.8 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 0.5 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 1.0 GO:0042599 lamellar body(GO:0042599)
0.0 0.5 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 0.6 GO:0036513 Derlin-1 retrotranslocation complex(GO:0036513)
0.0 0.8 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.9 GO:0000178 exosome (RNase complex)(GO:0000178)
0.0 0.2 GO:1990635 proximal dendrite(GO:1990635)
0.0 4.4 GO:0032587 ruffle membrane(GO:0032587)
0.0 0.1 GO:0031084 BLOC-2 complex(GO:0031084)
0.0 2.2 GO:0101003 ficolin-1-rich granule membrane(GO:0101003)
0.0 0.3 GO:0035631 CD40 receptor complex(GO:0035631)
0.0 0.2 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 0.9 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.0 0.8 GO:0001726 ruffle(GO:0001726)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 3.0 GO:0047225 acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0047225)
0.8 2.5 GO:0008859 exoribonuclease II activity(GO:0008859)
0.8 5.6 GO:0016019 peptidoglycan receptor activity(GO:0016019)
0.5 2.7 GO:0008665 2'-phosphotransferase activity(GO:0008665)
0.5 2.7 GO:0047718 androsterone dehydrogenase activity(GO:0047023) indanol dehydrogenase activity(GO:0047718)
0.4 3.1 GO:1990254 keratin filament binding(GO:1990254)
0.3 4.8 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.3 1.5 GO:0052740 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
0.2 3.2 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559)
0.2 3.4 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.2 0.7 GO:0070643 vitamin D3 25-hydroxylase activity(GO:0030343) vitamin D 25-hydroxylase activity(GO:0070643)
0.2 1.5 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.1 2.1 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.1 1.1 GO:0015181 arginine transmembrane transporter activity(GO:0015181)
0.1 4.3 GO:0003746 translation elongation factor activity(GO:0003746)
0.1 0.8 GO:0010858 calcium-dependent protein kinase regulator activity(GO:0010858)
0.1 2.0 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.1 1.3 GO:0102338 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.1 0.9 GO:0004126 cytidine deaminase activity(GO:0004126)
0.1 5.1 GO:0051183 vitamin transporter activity(GO:0051183)
0.1 0.5 GO:0004910 interleukin-1, Type II, blocking receptor activity(GO:0004910)
0.1 0.7 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.1 0.4 GO:0004917 interleukin-7 receptor activity(GO:0004917)
0.1 3.3 GO:0051787 misfolded protein binding(GO:0051787)
0.1 2.0 GO:0005212 structural constituent of eye lens(GO:0005212)
0.1 0.8 GO:0043515 kinetochore binding(GO:0043515)
0.1 8.0 GO:0097110 scaffold protein binding(GO:0097110)
0.1 0.6 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.1 0.5 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.1 0.5 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.1 0.9 GO:0000990 transcription factor activity, core RNA polymerase binding(GO:0000990)
0.1 0.4 GO:0001602 pancreatic polypeptide receptor activity(GO:0001602)
0.1 0.4 GO:0004949 cannabinoid receptor activity(GO:0004949)
0.1 2.7 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.1 0.5 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0 0.9 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 1.7 GO:0070034 telomerase RNA binding(GO:0070034)
0.0 0.3 GO:0045029 UDP-activated nucleotide receptor activity(GO:0045029)
0.0 1.1 GO:0031489 myosin V binding(GO:0031489)
0.0 1.3 GO:0017025 TBP-class protein binding(GO:0017025)
0.0 0.2 GO:0015265 urea channel activity(GO:0015265)
0.0 3.2 GO:0005179 hormone activity(GO:0005179)
0.0 2.2 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 3.6 GO:0048365 Rac GTPase binding(GO:0048365)
0.0 0.6 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0 1.1 GO:0005337 nucleoside transmembrane transporter activity(GO:0005337)
0.0 0.1 GO:0004329 formate-tetrahydrofolate ligase activity(GO:0004329)
0.0 4.9 GO:0031072 heat shock protein binding(GO:0031072)
0.0 2.5 GO:0004004 ATP-dependent RNA helicase activity(GO:0004004)
0.0 0.6 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.0 1.4 GO:0051393 alpha-actinin binding(GO:0051393)
0.0 0.2 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
0.0 0.3 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 4.2 GO:0008083 growth factor activity(GO:0008083)
0.0 1.8 GO:0002039 p53 binding(GO:0002039)
0.0 0.5 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.0 0.3 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.0 1.5 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 1.1 GO:0043621 protein self-association(GO:0043621)
0.0 2.0 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.2 GO:0008432 JUN kinase binding(GO:0008432)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 6.4 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.1 7.6 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.1 6.4 PID HNF3A PATHWAY FOXA1 transcription factor network
0.1 3.2 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 4.8 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.0 3.1 PID AURORA B PATHWAY Aurora B signaling
0.0 2.0 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions
0.0 1.2 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 3.3 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 1.5 PID RHOA PATHWAY RhoA signaling pathway
0.0 0.5 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 0.9 PID IL4 2PATHWAY IL4-mediated signaling events
0.0 2.0 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 0.5 PID IL1 PATHWAY IL1-mediated signaling events
0.0 0.8 PID PLK1 PATHWAY PLK1 signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 5.6 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.2 3.2 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.1 2.7 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.1 3.1 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 2.0 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.8 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 1.7 REACTOME EXTENSION OF TELOMERES Genes involved in Extension of Telomeres
0.0 1.3 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 0.9 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 0.6 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 2.7 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 1.5 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 1.3 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 0.3 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 3.0 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 1.1 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 0.7 REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
0.0 1.1 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.4 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.3 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 0.6 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.0 1.5 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.0 3.0 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 0.6 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.0 0.4 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.0 0.3 REACTOME INTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.0 0.1 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.0 1.4 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 0.5 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline