Project

SARS-CoV-2 Analysis Results (GEO series: GSE147507)

Navigation
Downloads

Results for KLF12

Z-value: 1.45

Motif logo

logo of

Transcription factors associated with KLF12

Gene Symbol Gene ID Gene Info
KLF12
ENSG00000118922.12 Kruppel like factor 12

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
KLF12hg19_v2_chr13_-_74708372_74708409-0.029.2e-01Click!

Activity profile of KLF12 motif

Sorted Z-values of KLF12 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr5_+_137801160 6.68 ENST00000239938.4
EGR1
early growth response 1
chr11_-_568369 4.79 ENST00000534540.1
ENST00000528245.1
ENST00000500447.1
ENST00000533920.1
MIR210HG
MIR210 host gene (non-protein coding)
chr12_-_54778471 3.18 ENST00000550120.1
ENST00000394313.2
ENST00000547210.1
ZNF385A
zinc finger protein 385A
chr6_+_31895467 2.70 ENST00000556679.1
ENST00000456570.1
CFB
CFB
complement factor B
Complement factor B; Uncharacterized protein; cDNA FLJ55673, highly similar to Complement factor B
chr6_+_31895480 2.32 ENST00000418949.2
ENST00000383177.3
ENST00000477310.1
C2
CFB
complement component 2
Complement factor B; Uncharacterized protein; cDNA FLJ55673, highly similar to Complement factor B
chr3_+_193853927 2.31 ENST00000232424.3
HES1
hes family bHLH transcription factor 1
chr9_+_35673853 2.31 ENST00000378357.4
CA9
carbonic anhydrase IX
chr12_-_54778444 2.27 ENST00000551771.1
ZNF385A
zinc finger protein 385A
chrX_-_48325857 2.24 ENST00000376875.1
SLC38A5
solute carrier family 38, member 5
chr15_-_90039805 2.18 ENST00000544600.1
ENST00000268122.4
RHCG
Rh family, C glycoprotein
chrX_+_152953505 2.12 ENST00000253122.5
SLC6A8
solute carrier family 6 (neurotransmitter transporter), member 8
chrX_+_68048803 2.10 ENST00000204961.4
EFNB1
ephrin-B1
chr1_+_24117627 2.07 ENST00000400061.1
LYPLA2
lysophospholipase II
chr19_-_45909585 2.06 ENST00000593226.1
ENST00000418234.2
PPP1R13L
protein phosphatase 1, regulatory subunit 13 like
chr15_-_41166414 2.06 ENST00000220507.4
RHOV
ras homolog family member V
chr2_+_234104079 2.05 ENST00000417661.1
INPP5D
inositol polyphosphate-5-phosphatase, 145kDa
chr8_+_124194875 2.01 ENST00000522648.1
ENST00000276699.6
FAM83A
family with sequence similarity 83, member A
chr1_-_153538011 2.00 ENST00000368707.4
S100A2
S100 calcium binding protein A2
chr8_+_124194752 1.84 ENST00000318462.6
FAM83A
family with sequence similarity 83, member A
chr12_-_54778244 1.79 ENST00000549937.1
ZNF385A
zinc finger protein 385A
chr17_+_1665253 1.74 ENST00000254722.4
SERPINF1
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
chr17_+_1665345 1.74 ENST00000576406.1
ENST00000571149.1
SERPINF1
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
chr6_+_33168597 1.73 ENST00000374675.3
SLC39A7
solute carrier family 39 (zinc transporter), member 7
chr17_-_80797886 1.66 ENST00000572562.1
ZNF750
zinc finger protein 750
chr22_-_37640456 1.65 ENST00000405484.1
ENST00000441619.1
ENST00000406508.1
RAC2
ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
chr6_+_33168637 1.56 ENST00000374677.3
SLC39A7
solute carrier family 39 (zinc transporter), member 7
chr19_-_3978083 1.54 ENST00000600794.1
EEF2
eukaryotic translation elongation factor 2
chr16_-_67978016 1.50 ENST00000264005.5
LCAT
lecithin-cholesterol acyltransferase
chr12_-_56120838 1.48 ENST00000548160.1
CD63
CD63 molecule
chr5_-_81046904 1.48 ENST00000515395.1
SSBP2
single-stranded DNA binding protein 2
chr19_+_5914213 1.48 ENST00000222125.5
ENST00000452990.2
ENST00000588865.1
CAPS
calcyphosine
chr11_-_57089671 1.46 ENST00000532437.1
TNKS1BP1
tankyrase 1 binding protein 1, 182kDa
chr3_-_49722523 1.35 ENST00000448220.1
MST1
macrophage stimulating 1 (hepatocyte growth factor-like)
chr12_-_56120865 1.34 ENST00000548898.1
ENST00000552067.1
CD63
CD63 molecule
chr4_-_74904398 1.31 ENST00000296026.4
CXCL3
chemokine (C-X-C motif) ligand 3
chr11_+_66360665 1.29 ENST00000310190.4
CCS
copper chaperone for superoxide dismutase
chr17_-_47841485 1.28 ENST00000506156.1
ENST00000240364.2
FAM117A
family with sequence similarity 117, member A
chr1_+_27561104 1.27 ENST00000361771.3
WDTC1
WD and tetratricopeptide repeats 1
chr3_-_61237050 1.25 ENST00000476844.1
ENST00000488467.1
ENST00000492590.1
ENST00000468189.1
FHIT
fragile histidine triad
chr22_-_39268308 1.25 ENST00000407418.3
CBX6
chromobox homolog 6
chr17_-_36831156 1.23 ENST00000325814.5
C17orf96
chromosome 17 open reading frame 96
chr2_+_208104351 1.21 ENST00000440326.1
AC007879.7
AC007879.7
chr18_+_29598335 1.20 ENST00000217740.3
RNF125
ring finger protein 125, E3 ubiquitin protein ligase
chr1_-_46598371 1.20 ENST00000372006.1
ENST00000425892.1
ENST00000420542.1
ENST00000354242.4
ENST00000340332.6
PIK3R3
phosphoinositide-3-kinase, regulatory subunit 3 (gamma)
chr17_+_7211280 1.20 ENST00000419711.2
ENST00000571955.1
ENST00000573714.1
EIF5A
eukaryotic translation initiation factor 5A
chr5_-_81046922 1.17 ENST00000514493.1
ENST00000320672.4
SSBP2
single-stranded DNA binding protein 2
chr1_+_27561007 1.15 ENST00000319394.3
WDTC1
WD and tetratricopeptide repeats 1
chr2_+_12858355 1.13 ENST00000405331.3
TRIB2
tribbles pseudokinase 2
chr2_+_208104497 1.12 ENST00000430494.1
AC007879.7
AC007879.7
chr9_-_34637718 1.10 ENST00000378892.1
ENST00000277010.4
SIGMAR1
sigma non-opioid intracellular receptor 1
chr6_-_33267101 1.08 ENST00000497454.1
RGL2
ral guanine nucleotide dissociation stimulator-like 2
chr10_-_77161650 1.08 ENST00000372524.4
ZNF503
zinc finger protein 503
chr14_+_65171315 1.07 ENST00000394691.1
PLEKHG3
pleckstrin homology domain containing, family G (with RhoGef domain) member 3
chr16_+_30671223 1.07 ENST00000568722.1
FBRS
fibrosin
chr17_+_1665306 1.07 ENST00000571360.1
SERPINF1
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
chr14_+_65171099 1.06 ENST00000247226.7
PLEKHG3
pleckstrin homology domain containing, family G (with RhoGef domain) member 3
chr4_-_87770416 1.06 ENST00000273905.6
SLC10A6
solute carrier family 10 (sodium/bile acid cotransporter), member 6
chrX_-_134156502 1.04 ENST00000391440.1
FAM127C
family with sequence similarity 127, member C
chr5_+_167181917 1.03 ENST00000519204.1
TENM2
teneurin transmembrane protein 2
chr22_-_24110063 1.02 ENST00000520222.1
ENST00000401675.3
CHCHD10
coiled-coil-helix-coiled-coil-helix domain containing 10
chr11_-_118889323 1.00 ENST00000527673.1
RPS25
ribosomal protein S25
chr11_-_125365435 0.99 ENST00000524435.1
FEZ1
fasciculation and elongation protein zeta 1 (zygin I)
chr9_+_96928516 0.98 ENST00000602703.1
RP11-2B6.3
RP11-2B6.3
chr8_+_145691411 0.97 ENST00000301332.2
KIFC2
kinesin family member C2
chr1_-_46598284 0.97 ENST00000423209.1
ENST00000262741.5
PIK3R3
phosphoinositide-3-kinase, regulatory subunit 3 (gamma)
chr10_-_52645416 0.95 ENST00000374001.2
ENST00000373997.3
ENST00000373995.3
ENST00000282641.2
ENST00000395495.1
ENST00000414883.1
A1CF
APOBEC1 complementation factor
chr7_-_127672146 0.94 ENST00000476782.1
LRRC4
leucine rich repeat containing 4
chr4_+_4387983 0.94 ENST00000397958.1
NSG1
Homo sapiens neuron specific gene family member 1 (NSG1), transcript variant 3, mRNA.
chr20_+_44637526 0.92 ENST00000372330.3
MMP9
matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)
chr1_+_1243947 0.91 ENST00000379031.5
PUSL1
pseudouridylate synthase-like 1
chr16_+_29819446 0.91 ENST00000568282.1
MAZ
MYC-associated zinc finger protein (purine-binding transcription factor)
chr10_-_71906342 0.89 ENST00000287078.6
ENST00000335494.5
TYSND1
trypsin domain containing 1
chr20_+_34287364 0.87 ENST00000374072.1
ENST00000397416.1
ENST00000336695.4
ROMO1
reactive oxygen species modulator 1
chr5_+_167182003 0.87 ENST00000520394.1
TENM2
teneurin transmembrane protein 2
chr5_-_142077569 0.86 ENST00000407758.1
ENST00000441680.2
ENST00000419524.2
FGF1
fibroblast growth factor 1 (acidic)
chr19_+_13051206 0.86 ENST00000586760.1
CALR
calreticulin
chr11_+_61248583 0.86 ENST00000432063.2
ENST00000338608.2
PPP1R32
protein phosphatase 1, regulatory subunit 32
chr19_-_51527467 0.86 ENST00000593681.1
KLK11
kallikrein-related peptidase 11
chr9_-_117853297 0.85 ENST00000542877.1
ENST00000537320.1
ENST00000341037.4
TNC
tenascin C
chr12_+_57482877 0.85 ENST00000342556.6
ENST00000357680.4
NAB2
NGFI-A binding protein 2 (EGR1 binding protein 2)
chr16_+_29819372 0.85 ENST00000568544.1
ENST00000569978.1
MAZ
MYC-associated zinc finger protein (purine-binding transcription factor)
chr8_+_37553261 0.85 ENST00000331569.4
ZNF703
zinc finger protein 703
chr11_-_65837090 0.85 ENST00000529036.1
RP11-1167A19.2
Uncharacterized protein
chr20_+_34287194 0.84 ENST00000374078.1
ENST00000374077.3
ROMO1
reactive oxygen species modulator 1
chr3_-_51994694 0.84 ENST00000395014.2
PCBP4
poly(rC) binding protein 4
chr10_-_77161533 0.83 ENST00000535216.1
ZNF503
zinc finger protein 503
chr16_+_28875126 0.81 ENST00000359285.5
ENST00000538342.1
SH2B1
SH2B adaptor protein 1
chr3_-_99833333 0.80 ENST00000354552.3
ENST00000331335.5
ENST00000398326.2
FILIP1L
filamin A interacting protein 1-like
chr5_-_81046841 0.80 ENST00000509013.2
ENST00000505980.1
ENST00000509053.1
SSBP2
single-stranded DNA binding protein 2
chr9_-_99064429 0.79 ENST00000375263.3
HSD17B3
hydroxysteroid (17-beta) dehydrogenase 3
chr10_+_104404218 0.77 ENST00000302424.7
TRIM8
tripartite motif containing 8
chr16_-_65106110 0.77 ENST00000562882.1
ENST00000567934.1
CDH11
cadherin 11, type 2, OB-cadherin (osteoblast)
chr19_-_55866061 0.77 ENST00000588572.2
ENST00000593184.1
ENST00000589467.1
COX6B2
cytochrome c oxidase subunit VIb polypeptide 2 (testis)
chr11_-_65374430 0.77 ENST00000532507.1
MAP3K11
mitogen-activated protein kinase kinase kinase 11
chr1_+_116915855 0.77 ENST00000295598.5
ATP1A1
ATPase, Na+/K+ transporting, alpha 1 polypeptide
chr19_+_45174724 0.76 ENST00000358777.4
CEACAM19
carcinoembryonic antigen-related cell adhesion molecule 19
chr1_-_19229014 0.75 ENST00000538839.1
ENST00000290597.5
ALDH4A1
aldehyde dehydrogenase 4 family, member A1
chr2_+_24272576 0.75 ENST00000380986.4
ENST00000452109.1
FKBP1B
FK506 binding protein 1B, 12.6 kDa
chr18_+_32173276 0.75 ENST00000591816.1
ENST00000588125.1
ENST00000598334.1
ENST00000588684.1
ENST00000554864.3
ENST00000399121.5
ENST00000595022.1
ENST00000269190.7
ENST00000399097.3
DTNA
dystrobrevin, alpha
chr5_+_52776228 0.74 ENST00000256759.3
FST
follistatin
chr6_-_134639180 0.74 ENST00000367858.5
SGK1
serum/glucocorticoid regulated kinase 1
chr5_-_2751762 0.73 ENST00000302057.5
ENST00000382611.6
IRX2
iroquois homeobox 2
chr16_+_28875268 0.73 ENST00000395532.4
SH2B1
SH2B adaptor protein 1
chr9_-_99064386 0.72 ENST00000375262.2
HSD17B3
hydroxysteroid (17-beta) dehydrogenase 3
chr1_+_16083154 0.71 ENST00000375771.1
FBLIM1
filamin binding LIM protein 1
chr5_-_124080203 0.71 ENST00000504926.1
ZNF608
zinc finger protein 608
chr1_+_6845384 0.71 ENST00000303635.7
CAMTA1
calmodulin binding transcription activator 1
chr1_+_24117693 0.71 ENST00000374503.3
ENST00000374502.3
LYPLA2
lysophospholipase II
chr13_-_46716969 0.71 ENST00000435666.2
LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr19_-_2050852 0.70 ENST00000541165.1
ENST00000591601.1
MKNK2
MAP kinase interacting serine/threonine kinase 2
chr11_-_61129335 0.70 ENST00000545361.1
ENST00000539128.1
ENST00000546151.1
ENST00000447532.2
CYB561A3
cytochrome b561 family, member A3
chr19_+_14063278 0.70 ENST00000254337.6
DCAF15
DDB1 and CUL4 associated factor 15
chr5_+_52776449 0.70 ENST00000396947.3
FST
follistatin
chr2_+_99953816 0.70 ENST00000289371.6
EIF5B
eukaryotic translation initiation factor 5B
chr6_+_43612750 0.69 ENST00000372165.4
ENST00000372163.4
RSPH9
radial spoke head 9 homolog (Chlamydomonas)
chr3_+_38032216 0.69 ENST00000416303.1
VILL
villin-like
chr2_+_105471969 0.69 ENST00000361360.2
POU3F3
POU class 3 homeobox 3
chr15_+_74218787 0.69 ENST00000261921.7
LOXL1
lysyl oxidase-like 1
chr15_+_40531243 0.69 ENST00000558055.1
ENST00000455577.2
PAK6
p21 protein (Cdc42/Rac)-activated kinase 6
chr17_-_79818354 0.67 ENST00000576541.1
ENST00000576380.1
ENST00000571617.1
ENST00000576052.1
ENST00000576390.1
ENST00000573778.2
ENST00000439918.2
ENST00000574914.1
ENST00000331483.4
P4HB
prolyl 4-hydroxylase, beta polypeptide
chr14_+_85996471 0.67 ENST00000330753.4
FLRT2
fibronectin leucine rich transmembrane protein 2
chr1_-_32687923 0.67 ENST00000309777.6
ENST00000344461.3
ENST00000373593.1
ENST00000545122.1
TMEM234
transmembrane protein 234
chr3_-_52567792 0.65 ENST00000307092.4
ENST00000422318.2
ENST00000459839.1
NT5DC2
5'-nucleotidase domain containing 2
chr17_-_41174424 0.65 ENST00000355653.3
VAT1
vesicle amine transport 1
chr3_+_9944492 0.64 ENST00000383814.3
ENST00000454190.2
ENST00000454992.1
IL17RE
interleukin 17 receptor E
chr15_+_64428529 0.64 ENST00000560861.1
SNX1
sorting nexin 1
chr20_-_3154162 0.63 ENST00000360342.3
LZTS3
Homo sapiens leucine zipper, putative tumor suppressor family member 3 (LZTS3), mRNA.
chr8_-_145086922 0.63 ENST00000530478.1
PARP10
poly (ADP-ribose) polymerase family, member 10
chr7_+_128502895 0.62 ENST00000492758.1
ATP6V1F
ATPase, H+ transporting, lysosomal 14kDa, V1 subunit F
chr7_-_127671674 0.62 ENST00000478726.1
LRRC4
leucine rich repeat containing 4
chr1_-_116383738 0.62 ENST00000320238.3
NHLH2
nescient helix loop helix 2
chr8_+_22022653 0.62 ENST00000354870.5
ENST00000397816.3
ENST00000306349.8
BMP1
bone morphogenetic protein 1
chr1_+_109792641 0.61 ENST00000271332.3
CELSR2
cadherin, EGF LAG seven-pass G-type receptor 2
chr11_+_62475130 0.61 ENST00000294117.5
GNG3
guanine nucleotide binding protein (G protein), gamma 3
chr12_-_6772303 0.61 ENST00000396807.4
ENST00000446105.2
ENST00000341550.4
ING4
inhibitor of growth family, member 4
chr3_+_50316458 0.61 ENST00000316436.3
LSMEM2
leucine-rich single-pass membrane protein 2
chr17_+_2240775 0.61 ENST00000268989.3
ENST00000426855.2
SGSM2
small G protein signaling modulator 2
chr14_+_85996507 0.61 ENST00000554746.1
FLRT2
fibronectin leucine rich transmembrane protein 2
chr5_-_121413974 0.61 ENST00000231004.4
LOX
lysyl oxidase
chr6_-_34216766 0.61 ENST00000481533.1
ENST00000468145.1
ENST00000413013.2
ENST00000394990.4
ENST00000335352.3
C6orf1
chromosome 6 open reading frame 1
chr2_+_220306745 0.60 ENST00000431523.1
ENST00000396698.1
ENST00000396695.2
SPEG
SPEG complex locus
chr1_+_24117662 0.60 ENST00000420982.1
ENST00000374505.2
LYPLA2
lysophospholipase II
chr14_+_104182061 0.60 ENST00000216602.6
ZFYVE21
zinc finger, FYVE domain containing 21
chr1_-_202777535 0.60 ENST00000367264.2
KDM5B
lysine (K)-specific demethylase 5B
chr19_-_46389359 0.60 ENST00000302165.3
IRF2BP1
interferon regulatory factor 2 binding protein 1
chr2_+_219745020 0.60 ENST00000258411.3
WNT10A
wingless-type MMTV integration site family, member 10A
chr17_+_7210852 0.59 ENST00000576930.1
EIF5A
eukaryotic translation initiation factor 5A
chr12_-_56122220 0.59 ENST00000552692.1
CD63
CD63 molecule
chr9_-_122131696 0.59 ENST00000373964.2
ENST00000265922.3
BRINP1
bone morphogenetic protein/retinoic acid inducible neural-specific 1
chr12_+_120740119 0.59 ENST00000536460.1
ENST00000202967.4
SIRT4
sirtuin 4
chr19_+_45174994 0.59 ENST00000403660.3
CEACAM19
carcinoembryonic antigen-related cell adhesion molecule 19
chr10_-_103880209 0.58 ENST00000425280.1
LDB1
LIM domain binding 1
chr15_+_40531621 0.58 ENST00000560346.1
PAK6
p21 protein (Cdc42/Rac)-activated kinase 6
chr17_-_40828969 0.57 ENST00000591022.1
ENST00000587627.1
ENST00000293349.6
PLEKHH3
pleckstrin homology domain containing, family H (with MyTH4 domain) member 3
chr1_+_206730484 0.57 ENST00000304534.8
RASSF5
Ras association (RalGDS/AF-6) domain family member 5
chr12_-_56122124 0.57 ENST00000552754.1
CD63
CD63 molecule
chr10_-_105437909 0.56 ENST00000540321.1
SH3PXD2A
SH3 and PX domains 2A
chr6_-_134639042 0.56 ENST00000461976.2
SGK1
serum/glucocorticoid regulated kinase 1
chr22_-_38699003 0.56 ENST00000451964.1
CSNK1E
casein kinase 1, epsilon
chr6_-_43021612 0.55 ENST00000535468.1
CUL7
cullin 7
chr6_+_116832789 0.55 ENST00000368599.3
FAM26E
family with sequence similarity 26, member E
chr22_-_30198075 0.55 ENST00000411532.1
ASCC2
activating signal cointegrator 1 complex subunit 2
chr1_-_38512450 0.55 ENST00000373012.2
POU3F1
POU class 3 homeobox 1
chr3_-_69370095 0.54 ENST00000473029.1
FRMD4B
FERM domain containing 4B
chr17_+_7210921 0.54 ENST00000573542.1
EIF5A
eukaryotic translation initiation factor 5A
chr10_+_45869652 0.52 ENST00000542434.1
ENST00000374391.2
ALOX5
arachidonate 5-lipoxygenase
chr17_-_40829026 0.51 ENST00000412503.1
PLEKHH3
pleckstrin homology domain containing, family H (with MyTH4 domain) member 3
chr10_+_23983671 0.51 ENST00000376462.1
KIAA1217
KIAA1217
chr11_-_63993690 0.51 ENST00000394546.2
ENST00000541278.1
TRPT1
tRNA phosphotransferase 1
chr17_-_36906058 0.51 ENST00000580830.1
PCGF2
polycomb group ring finger 2
chr6_-_114292284 0.51 ENST00000520895.1
ENST00000521163.1
ENST00000524334.1
ENST00000368632.2
ENST00000398283.2
HDAC2
histone deacetylase 2
chr7_+_143080063 0.50 ENST00000446634.1
ZYX
zyxin
chr18_+_19749386 0.50 ENST00000269216.3
GATA6
GATA binding protein 6
chr16_-_1843694 0.50 ENST00000569769.1
SPSB3
splA/ryanodine receptor domain and SOCS box containing 3
chr5_+_139493665 0.50 ENST00000331327.3
PURA
purine-rich element binding protein A
chr1_+_154193325 0.50 ENST00000428931.1
ENST00000441890.1
ENST00000271877.7
ENST00000412596.1
ENST00000368504.1
ENST00000437652.1
UBAP2L
ubiquitin associated protein 2-like
chr7_+_18330035 0.49 ENST00000413509.2
HDAC9
histone deacetylase 9
chr1_+_153600869 0.49 ENST00000292169.1
ENST00000368696.3
ENST00000436839.1
S100A1
S100 calcium binding protein A1
chr9_+_131445703 0.49 ENST00000454747.1
SET
SET nuclear oncogene
chr14_-_74417096 0.48 ENST00000286544.3
FAM161B
family with sequence similarity 161, member B
chr3_+_23244511 0.48 ENST00000425792.1
UBE2E2
ubiquitin-conjugating enzyme E2E 2
chr10_+_121578211 0.48 ENST00000369080.3
INPP5F
inositol polyphosphate-5-phosphatase F
chr3_-_113415441 0.48 ENST00000491165.1
ENST00000316407.4
KIAA2018
KIAA2018
chr6_-_114292449 0.48 ENST00000519065.1
HDAC2
histone deacetylase 2
chr2_+_89952792 0.48 ENST00000390265.2
IGKV1D-33
immunoglobulin kappa variable 1D-33
chr1_+_145209092 0.47 ENST00000362074.6
ENST00000344859.3
NOTCH2NL
notch 2 N-terminal like
chr19_+_19303572 0.47 ENST00000407360.3
ENST00000540981.1
RFXANK
regulatory factor X-associated ankyrin-containing protein
chr5_-_179227540 0.47 ENST00000520875.1
MGAT4B
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme B
chr8_+_22022800 0.47 ENST00000397814.3
BMP1
bone morphogenetic protein 1
chr2_+_24272543 0.46 ENST00000380991.4
FKBP1B
FK506 binding protein 1B, 12.6 kDa
chr7_+_70229899 0.46 ENST00000443672.1
AUTS2
autism susceptibility candidate 2
chrX_-_37706661 0.46 ENST00000432389.2
ENST00000378581.3
DYNLT3
dynein, light chain, Tctex-type 3
chr2_+_173724771 0.46 ENST00000538974.1
ENST00000540783.1
RAPGEF4
Rap guanine nucleotide exchange factor (GEF) 4
chr3_+_29322803 0.46 ENST00000396583.3
ENST00000383767.2
RBMS3
RNA binding motif, single stranded interacting protein 3
chr19_+_19303720 0.46 ENST00000392324.4
RFXANK
regulatory factor X-associated ankyrin-containing protein
chr15_-_43865633 0.45 ENST00000437065.1
PPIP5K1
diphosphoinositol pentakisphosphate kinase 1
chr20_-_2821271 0.44 ENST00000448755.1
ENST00000360652.2
PCED1A
PC-esterase domain containing 1A
chr12_-_10826612 0.44 ENST00000535345.1
ENST00000542562.1
STYK1
serine/threonine/tyrosine kinase 1
chr16_+_3019246 0.44 ENST00000318782.8
ENST00000293978.8
PAQR4
progestin and adipoQ receptor family member IV
chr1_-_155177677 0.44 ENST00000368378.3
ENST00000541990.1
ENST00000457183.2
THBS3
thrombospondin 3

Network of associatons between targets according to the STRING database.

First level regulatory network of KLF12

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
2.2 6.7 GO:0050720 regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362) interleukin-1 beta biosynthetic process(GO:0050720)
1.0 7.2 GO:1902164 mRNA localization resulting in posttranscriptional regulation of gene expression(GO:0010609) regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902162) positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902164)
0.8 2.3 GO:2000974 auditory receptor cell fate determination(GO:0042668) negative regulation of auditory receptor cell differentiation(GO:0045608) negative regulation of pro-B cell differentiation(GO:2000974)
0.7 2.2 GO:0070634 transepithelial ammonium transport(GO:0070634)
0.7 2.1 GO:0015881 creatine transport(GO:0015881) creatine transmembrane transport(GO:1902598)
0.6 4.5 GO:0071279 cellular response to cobalt ion(GO:0071279)
0.4 1.3 GO:0015680 intracellular copper ion transport(GO:0015680)
0.4 2.1 GO:0045658 regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
0.4 1.1 GO:0045081 negative regulation of interleukin-10 biosynthetic process(GO:0045081)
0.3 3.8 GO:0002084 protein depalmitoylation(GO:0002084)
0.3 4.4 GO:0035826 rubidium ion transport(GO:0035826) regulation of rubidium ion transport(GO:2000680)
0.3 1.5 GO:0090107 regulation of high-density lipoprotein particle assembly(GO:0090107)
0.3 1.0 GO:0034499 late endosome to Golgi transport(GO:0034499)
0.2 0.7 GO:0072086 specification of loop of Henle identity(GO:0072086)
0.2 0.7 GO:0051693 actin filament capping(GO:0051693)
0.2 2.0 GO:0006452 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.2 5.0 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.2 1.3 GO:0061343 cell adhesion involved in heart morphogenesis(GO:0061343)
0.2 0.9 GO:0060447 bud outgrowth involved in lung branching(GO:0060447)
0.2 0.6 GO:1903217 regulation of protein processing involved in protein targeting to mitochondrion(GO:1903216) negative regulation of protein processing involved in protein targeting to mitochondrion(GO:1903217)
0.2 1.9 GO:0070315 G1 to G0 transition involved in cell differentiation(GO:0070315)
0.2 0.7 GO:0018277 protein deamination(GO:0018277)
0.2 0.5 GO:0043311 regulation of eosinophil degranulation(GO:0043309) positive regulation of eosinophil degranulation(GO:0043311) positive regulation of eosinophil activation(GO:1902568)
0.2 1.7 GO:0051715 cytolysis in other organism(GO:0051715)
0.2 0.5 GO:0007493 endodermal cell fate determination(GO:0007493)
0.2 1.9 GO:0070294 renal sodium ion absorption(GO:0070294)
0.2 0.8 GO:0043983 histone H4-K12 acetylation(GO:0043983)
0.2 1.7 GO:0060753 regulation of mast cell chemotaxis(GO:0060753)
0.1 0.6 GO:0034721 histone H3-K4 demethylation, trimethyl-H3-K4-specific(GO:0034721)
0.1 0.9 GO:0002501 peptide antigen assembly with MHC protein complex(GO:0002501)
0.1 0.9 GO:0016480 negative regulation of transcription from RNA polymerase III promoter(GO:0016480)
0.1 1.0 GO:0006344 maintenance of chromatin silencing(GO:0006344)
0.1 1.5 GO:2000767 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183) positive regulation of cytoplasmic translation(GO:2000767)
0.1 1.5 GO:0061370 testosterone biosynthetic process(GO:0061370)
0.1 0.5 GO:0014859 negative regulation of skeletal muscle cell proliferation(GO:0014859) negative regulation of skeletal muscle satellite cell proliferation(GO:1902723)
0.1 2.4 GO:0015816 glycine transport(GO:0015816)
0.1 0.6 GO:0010847 regulation of chromatin assembly(GO:0010847) protein auto-ADP-ribosylation(GO:0070213)
0.1 0.8 GO:0019470 4-hydroxyproline catabolic process(GO:0019470)
0.1 1.9 GO:0097264 self proteolysis(GO:0097264)
0.1 1.0 GO:0097398 response to interleukin-17(GO:0097396) cellular response to interleukin-17(GO:0097398)
0.1 0.5 GO:0098582 innate vocalization behavior(GO:0098582)
0.1 0.7 GO:0072069 DCT cell differentiation(GO:0072069) metanephric DCT cell differentiation(GO:0072240)
0.1 1.4 GO:0016554 cytidine to uridine editing(GO:0016554)
0.1 0.5 GO:0018283 metal incorporation into metallo-sulfur cluster(GO:0018282) iron incorporation into metallo-sulfur cluster(GO:0018283)
0.1 0.3 GO:0031204 posttranslational protein targeting to membrane, translocation(GO:0031204)
0.1 0.3 GO:1990709 presynaptic active zone organization(GO:1990709)
0.1 0.9 GO:0051549 positive regulation of keratinocyte migration(GO:0051549)
0.1 0.3 GO:1901254 modulation by host of viral RNA genome replication(GO:0044830) positive regulation of intracellular transport of viral material(GO:1901254)
0.1 1.2 GO:0010459 negative regulation of heart rate(GO:0010459)
0.1 0.3 GO:0071586 CAAX-box protein processing(GO:0071586) CAAX-box protein maturation(GO:0080120)
0.1 2.4 GO:0045717 negative regulation of fatty acid biosynthetic process(GO:0045717)
0.1 0.3 GO:0045226 extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379)
0.1 0.3 GO:0031446 regulation of fast-twitch skeletal muscle fiber contraction(GO:0031446) positive regulation of fast-twitch skeletal muscle fiber contraction(GO:0031448) maintenance of mitochondrion location(GO:0051659)
0.1 1.1 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
0.1 0.8 GO:0007256 activation of JNKK activity(GO:0007256)
0.1 0.3 GO:0060061 Spemann organizer formation(GO:0060061)
0.1 0.6 GO:0046985 positive regulation of hemoglobin biosynthetic process(GO:0046985)
0.1 0.9 GO:0031119 tRNA pseudouridine synthesis(GO:0031119)
0.1 0.6 GO:0072674 multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675)
0.1 0.9 GO:0032351 negative regulation of glucocorticoid metabolic process(GO:0031944) negative regulation of glucocorticoid biosynthetic process(GO:0031947) negative regulation of hormone metabolic process(GO:0032351) negative regulation of hormone biosynthetic process(GO:0032353) negative regulation of steroid hormone biosynthetic process(GO:0090032)
0.1 0.5 GO:0061484 hematopoietic stem cell homeostasis(GO:0061484)
0.1 1.0 GO:1902902 negative regulation of autophagosome assembly(GO:1902902)
0.1 1.7 GO:0097119 postsynaptic density protein 95 clustering(GO:0097119)
0.1 0.9 GO:2000544 cell chemotaxis to fibroblast growth factor(GO:0035766) endothelial cell chemotaxis to fibroblast growth factor(GO:0035768) regulation of cell chemotaxis to fibroblast growth factor(GO:1904847) regulation of endothelial cell chemotaxis to fibroblast growth factor(GO:2000544)
0.1 3.3 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.1 0.8 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.1 0.8 GO:0033601 positive regulation of mammary gland epithelial cell proliferation(GO:0033601)
0.1 0.9 GO:0098887 neurotransmitter receptor transport, endosome to postsynaptic membrane(GO:0098887)
0.1 2.1 GO:0003215 cardiac right ventricle morphogenesis(GO:0003215)
0.1 0.7 GO:0038003 opioid receptor signaling pathway(GO:0038003)
0.1 0.6 GO:0032057 negative regulation of translational initiation in response to stress(GO:0032057)
0.1 0.3 GO:0032796 uropod organization(GO:0032796)
0.1 0.1 GO:0098905 regulation of bundle of His cell action potential(GO:0098905)
0.1 1.1 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)
0.1 0.6 GO:1900180 regulation of protein localization to nucleus(GO:1900180)
0.1 0.6 GO:0070120 ciliary neurotrophic factor-mediated signaling pathway(GO:0070120)
0.1 0.7 GO:0034378 chylomicron assembly(GO:0034378)
0.1 0.7 GO:0097475 motor neuron migration(GO:0097475)
0.1 0.8 GO:0048733 sebaceous gland development(GO:0048733)
0.1 0.3 GO:0071543 diadenosine polyphosphate catabolic process(GO:0015961) diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.1 0.3 GO:0030047 actin modification(GO:0030047)
0.1 0.2 GO:0050960 detection of temperature stimulus involved in thermoception(GO:0050960) positive regulation of gastric acid secretion(GO:0060454) response to capsazepine(GO:1901594)
0.1 0.5 GO:2001300 lipoxin metabolic process(GO:2001300)
0.1 0.6 GO:0021999 neural plate anterior/posterior regionalization(GO:0021999) neural plate regionalization(GO:0060897)
0.1 2.2 GO:2001275 positive regulation of glucose import in response to insulin stimulus(GO:2001275)
0.1 0.2 GO:1990637 response to prolactin(GO:1990637)
0.0 1.1 GO:0034380 high-density lipoprotein particle assembly(GO:0034380)
0.0 0.2 GO:0035616 histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.0 1.1 GO:0006020 inositol metabolic process(GO:0006020)
0.0 0.6 GO:0048251 elastic fiber assembly(GO:0048251)
0.0 0.9 GO:0060294 cilium movement involved in cell motility(GO:0060294)
0.0 0.9 GO:0031998 regulation of fatty acid beta-oxidation(GO:0031998)
0.0 1.1 GO:1902187 negative regulation of viral release from host cell(GO:1902187)
0.0 0.9 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0 0.8 GO:0021957 corticospinal tract morphogenesis(GO:0021957)
0.0 0.5 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.0 0.1 GO:1902725 negative regulation of satellite cell differentiation(GO:1902725)
0.0 0.5 GO:1901387 positive regulation of voltage-gated calcium channel activity(GO:1901387)
0.0 0.6 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.0 0.4 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.0 0.7 GO:0033623 regulation of integrin activation(GO:0033623)
0.0 2.3 GO:0006730 one-carbon metabolic process(GO:0006730)
0.0 0.6 GO:0006307 DNA dealkylation involved in DNA repair(GO:0006307)
0.0 0.2 GO:1903385 regulation of homophilic cell adhesion(GO:1903385)
0.0 0.3 GO:0060413 atrial septum morphogenesis(GO:0060413)
0.0 0.2 GO:0060023 soft palate development(GO:0060023)
0.0 0.7 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.0 0.7 GO:0042711 maternal behavior(GO:0042711) parental behavior(GO:0060746)
0.0 0.5 GO:0039536 negative regulation of RIG-I signaling pathway(GO:0039536)
0.0 0.5 GO:0042532 negative regulation of tyrosine phosphorylation of STAT protein(GO:0042532)
0.0 0.3 GO:0045919 positive regulation of cytolysis(GO:0045919)
0.0 0.3 GO:0030263 apoptotic chromosome condensation(GO:0030263)
0.0 0.5 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.0 1.1 GO:0010667 negative regulation of cardiac muscle cell apoptotic process(GO:0010667)
0.0 0.4 GO:0060346 bone trabecula formation(GO:0060346)
0.0 0.2 GO:0006543 glutamine catabolic process(GO:0006543)
0.0 1.4 GO:0001755 neural crest cell migration(GO:0001755)
0.0 1.3 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.0 0.5 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.0 0.7 GO:0071243 cellular response to arsenic-containing substance(GO:0071243)
0.0 0.3 GO:0033211 adiponectin-activated signaling pathway(GO:0033211) response to oleic acid(GO:0034201)
0.0 2.3 GO:0042147 retrograde transport, endosome to Golgi(GO:0042147)
0.0 0.3 GO:0030091 protein repair(GO:0030091)
0.0 0.2 GO:0034332 adherens junction organization(GO:0034332)
0.0 0.4 GO:0047484 regulation of response to osmotic stress(GO:0047484)
0.0 0.6 GO:0007617 mating behavior(GO:0007617) reproductive behavior(GO:0019098) multi-organism reproductive behavior(GO:0044705)
0.0 0.8 GO:0090383 phagosome acidification(GO:0090383)
0.0 0.4 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.0 0.6 GO:0022011 myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292)
0.0 0.2 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
0.0 0.1 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.0 1.5 GO:0045840 positive regulation of mitotic nuclear division(GO:0045840)
0.0 0.1 GO:0006540 glutamate decarboxylation to succinate(GO:0006540)
0.0 0.1 GO:0003365 establishment of cell polarity involved in ameboidal cell migration(GO:0003365)
0.0 0.2 GO:0071492 cellular response to UV-A(GO:0071492)
0.0 0.3 GO:0071372 positive regulation of collateral sprouting(GO:0048672) cellular response to follicle-stimulating hormone stimulus(GO:0071372)
0.0 0.4 GO:0071985 multivesicular body sorting pathway(GO:0071985)
0.0 0.3 GO:0045475 locomotor rhythm(GO:0045475)
0.0 0.6 GO:2000052 positive regulation of non-canonical Wnt signaling pathway(GO:2000052)
0.0 0.2 GO:0034350 regulation of glial cell apoptotic process(GO:0034350) negative regulation of glial cell apoptotic process(GO:0034351)
0.0 4.4 GO:0007173 epidermal growth factor receptor signaling pathway(GO:0007173)
0.0 2.0 GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest(GO:0006977)
0.0 0.4 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0 0.1 GO:0007288 sperm axoneme assembly(GO:0007288)
0.0 0.1 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197)
0.0 0.3 GO:0050995 negative regulation of lipid catabolic process(GO:0050995)
0.0 0.2 GO:0031580 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.0 0.8 GO:0071377 cellular response to glucagon stimulus(GO:0071377)
0.0 0.1 GO:0021800 cerebral cortex tangential migration(GO:0021800)
0.0 0.2 GO:0061734 parkin-mediated mitophagy in response to mitochondrial depolarization(GO:0061734)
0.0 0.7 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.0 0.2 GO:0045647 negative regulation of erythrocyte differentiation(GO:0045647)
0.0 0.3 GO:0035107 appendage morphogenesis(GO:0035107) limb morphogenesis(GO:0035108)
0.0 0.1 GO:0070272 proton-transporting ATP synthase complex assembly(GO:0043461) proton-transporting ATP synthase complex biogenesis(GO:0070272)
0.0 0.5 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.0 0.3 GO:0018027 peptidyl-lysine dimethylation(GO:0018027)
0.0 1.0 GO:0006754 ATP biosynthetic process(GO:0006754)
0.0 0.1 GO:0032364 oxygen homeostasis(GO:0032364)
0.0 0.5 GO:0006491 N-glycan processing(GO:0006491)
0.0 0.2 GO:0048743 positive regulation of skeletal muscle fiber development(GO:0048743)
0.0 0.4 GO:0050962 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.0 0.1 GO:0008343 adult feeding behavior(GO:0008343)
0.0 0.1 GO:0051012 microtubule sliding(GO:0051012)
0.0 0.1 GO:0090116 C-5 methylation of cytosine(GO:0090116)
0.0 0.3 GO:0044804 nucleophagy(GO:0044804)
0.0 0.1 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
0.0 0.2 GO:0090023 positive regulation of neutrophil chemotaxis(GO:0090023)
0.0 0.2 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 0.3 GO:0030324 lung development(GO:0030324)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.4 GO:0030895 apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.3 4.4 GO:0097487 multivesicular body, internal vesicle(GO:0097487)
0.2 4.5 GO:0043203 axon hillock(GO:0043203)
0.2 0.7 GO:0016222 procollagen-proline 4-dioxygenase complex(GO:0016222)
0.2 2.3 GO:0005642 annulate lamellae(GO:0005642)
0.1 1.8 GO:0042788 polysomal ribosome(GO:0042788)
0.1 0.6 GO:0097059 CNTFR-CLCF1 complex(GO:0097059)
0.1 0.9 GO:0098845 postsynaptic endosome(GO:0098845)
0.1 0.9 GO:0042824 MHC class I peptide loading complex(GO:0042824)
0.1 0.3 GO:0036117 hyaluranon cable(GO:0036117)
0.1 0.4 GO:0042721 mitochondrial inner membrane protein insertion complex(GO:0042721)
0.1 0.6 GO:0030905 retromer, tubulation complex(GO:0030905)
0.1 1.2 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.1 0.7 GO:0001739 sex chromatin(GO:0001739)
0.1 0.3 GO:0014802 terminal cisterna(GO:0014802)
0.1 2.3 GO:0031528 microvillus membrane(GO:0031528)
0.1 0.9 GO:0042579 peroxisome(GO:0005777) microbody(GO:0042579)
0.1 0.6 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
0.1 0.6 GO:0031467 Cul7-RING ubiquitin ligase complex(GO:0031467)
0.1 0.8 GO:0030061 mitochondrial crista(GO:0030061)
0.0 1.6 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.3 GO:1990131 Gtr1-Gtr2 GTPase complex(GO:1990131)
0.0 0.2 GO:0036156 inner dynein arm(GO:0036156)
0.0 0.6 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0 1.1 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.3 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 0.5 GO:0000322 storage vacuole(GO:0000322)
0.0 1.1 GO:0030014 CCR4-NOT complex(GO:0030014)
0.0 0.9 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0 0.3 GO:1990111 spermatoproteasome complex(GO:1990111)
0.0 1.0 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.5 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 1.5 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 0.2 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.0 0.1 GO:0032279 asymmetric synapse(GO:0032279)
0.0 0.3 GO:0061574 ASAP complex(GO:0061574)
0.0 1.0 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.3 GO:0042567 insulin-like growth factor ternary complex(GO:0042567)
0.0 0.2 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0 0.5 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0 0.3 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 4.2 GO:0072562 blood microparticle(GO:0072562)
0.0 0.3 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.0 0.3 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.2 GO:0014704 intercalated disc(GO:0014704)
0.0 1.8 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.0 0.1 GO:0097361 CIA complex(GO:0097361)
0.0 0.3 GO:0060077 inhibitory synapse(GO:0060077)
0.0 0.2 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.0 3.0 GO:0016605 PML body(GO:0016605)
0.0 1.7 GO:0000792 heterochromatin(GO:0000792)
0.0 0.2 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.0 1.1 GO:0045171 intercellular bridge(GO:0045171)
0.0 6.1 GO:0000790 nuclear chromatin(GO:0000790)
0.0 1.0 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 1.4 GO:0034704 calcium channel complex(GO:0034704)
0.0 0.5 GO:0032839 dendrite cytoplasm(GO:0032839)
0.0 0.6 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 0.3 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.0 0.5 GO:0032590 dendrite membrane(GO:0032590)
0.0 1.0 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 0.4 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.4 GO:0032809 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0 1.7 GO:0010008 endosome membrane(GO:0010008)
0.0 1.0 GO:0005871 kinesin complex(GO:0005871)
0.0 0.3 GO:0032281 AMPA glutamate receptor complex(GO:0032281)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 5.2 GO:0044729 hemi-methylated DNA-binding(GO:0044729)
0.7 2.1 GO:0005308 creatine transmembrane transporter activity(GO:0005308)
0.4 2.2 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.3 1.3 GO:0016532 superoxide dismutase copper chaperone activity(GO:0016532)
0.3 0.3 GO:0019956 chemokine binding(GO:0019956)
0.3 3.8 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.3 2.1 GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.3 0.8 GO:0003842 1-pyrroline-5-carboxylate dehydrogenase activity(GO:0003842)
0.2 1.5 GO:0034186 apolipoprotein A-I binding(GO:0034186)
0.2 1.2 GO:0005219 ryanodine-sensitive calcium-release channel activity(GO:0005219)
0.2 1.5 GO:0047045 testosterone 17-beta-dehydrogenase (NADP+) activity(GO:0047045)
0.2 0.8 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.2 3.8 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.2 5.9 GO:0001848 complement binding(GO:0001848)
0.2 0.5 GO:0031071 cysteine desulfurase activity(GO:0031071)
0.2 1.1 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.1 0.6 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)
0.1 0.6 GO:0047708 biotinidase activity(GO:0047708)
0.1 2.0 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.1 1.1 GO:0033857 diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.1 0.5 GO:0016230 sphingomyelin phosphodiesterase activator activity(GO:0016230)
0.1 0.6 GO:1990460 leptin receptor binding(GO:1990460)
0.1 0.5 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.1 1.0 GO:0000285 1-phosphatidylinositol-3-phosphate 5-kinase activity(GO:0000285)
0.1 0.4 GO:0030943 mitochondrion targeting sequence binding(GO:0030943)
0.1 2.2 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.1 2.3 GO:0017070 U6 snRNA binding(GO:0017070)
0.1 1.0 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.1 1.5 GO:0008097 5S rRNA binding(GO:0008097)
0.1 0.5 GO:0008665 2'-phosphotransferase activity(GO:0008665)
0.1 1.1 GO:0071532 ankyrin repeat binding(GO:0071532)
0.1 0.3 GO:0005169 neurotrophin TRKB receptor binding(GO:0005169)
0.1 0.5 GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978)
0.1 1.3 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.1 0.9 GO:0045545 syndecan binding(GO:0045545)
0.1 0.8 GO:0042296 ISG15 transferase activity(GO:0042296)
0.1 1.0 GO:0032051 clathrin light chain binding(GO:0032051)
0.1 0.9 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.1 1.6 GO:0004551 nucleotide diphosphatase activity(GO:0004551)
0.1 0.7 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656) procollagen-proline dioxygenase activity(GO:0019798)
0.1 0.7 GO:0004985 opioid receptor activity(GO:0004985)
0.1 3.3 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.1 2.1 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.1 0.4 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.1 0.6 GO:0004897 ciliary neurotrophic factor receptor activity(GO:0004897)
0.1 8.7 GO:0002039 p53 binding(GO:0002039)
0.1 2.8 GO:0030506 ankyrin binding(GO:0030506)
0.1 0.7 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.1 0.5 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.1 0.5 GO:0004359 glutaminase activity(GO:0004359)
0.1 0.5 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.1 1.1 GO:0055106 ubiquitin-protein transferase regulator activity(GO:0055106)
0.1 1.8 GO:0017081 chloride channel regulator activity(GO:0017081)
0.1 0.3 GO:0004096 catalase activity(GO:0004096)
0.1 0.3 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.1 1.2 GO:0048185 activin binding(GO:0048185)
0.1 0.5 GO:0052834 inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate 3-phosphatase activity(GO:0052832) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834)
0.0 0.9 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 0.6 GO:0030274 LIM domain binding(GO:0030274)
0.0 1.5 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0 0.3 GO:0034046 poly(G) binding(GO:0034046)
0.0 0.3 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.0 0.4 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.0 0.0 GO:0004566 beta-glucuronidase activity(GO:0004566)
0.0 0.4 GO:0070097 delta-catenin binding(GO:0070097)
0.0 1.7 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 5.1 GO:0042826 histone deacetylase binding(GO:0042826)
0.0 0.6 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 4.6 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.2 GO:0000150 recombinase activity(GO:0000150)
0.0 0.6 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.3 GO:0038049 transcription factor activity, ligand-activated RNA polymerase II transcription factor binding(GO:0038049)
0.0 0.1 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.7 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.0 0.7 GO:0071837 HMG box domain binding(GO:0071837)
0.0 0.2 GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.0 0.7 GO:0031005 filamin binding(GO:0031005)
0.0 0.2 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.0 0.8 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.0 0.5 GO:0044548 S100 protein binding(GO:0044548)
0.0 1.3 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 1.0 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 0.3 GO:0032036 myosin heavy chain binding(GO:0032036)
0.0 0.3 GO:0045159 myosin II binding(GO:0045159)
0.0 0.3 GO:0051219 phosphoprotein binding(GO:0051219)
0.0 0.1 GO:0000992 polymerase III regulatory region sequence-specific DNA binding(GO:0000992) RNA polymerase III type 1 promoter sequence-specific DNA binding(GO:0001002) RNA polymerase III type 2 promoter sequence-specific DNA binding(GO:0001003)
0.0 0.1 GO:0003998 acylphosphatase activity(GO:0003998)
0.0 0.2 GO:0003796 lysozyme activity(GO:0003796)
0.0 0.1 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.0 0.4 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.1 GO:0003696 satellite DNA binding(GO:0003696)
0.0 2.0 GO:0003727 single-stranded RNA binding(GO:0003727)
0.0 2.8 GO:0003697 single-stranded DNA binding(GO:0003697)
0.0 0.1 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.0 0.1 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0 0.1 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.0 0.6 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 0.5 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.0 0.4 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.1 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.0 0.2 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.0 1.3 GO:0070491 repressing transcription factor binding(GO:0070491)
0.0 0.3 GO:0005328 neurotransmitter:sodium symporter activity(GO:0005328)
0.0 0.2 GO:0005000 vasopressin receptor activity(GO:0005000)
0.0 1.5 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 0.1 GO:0032393 MHC class I receptor activity(GO:0032393)
0.0 0.6 GO:0005109 frizzled binding(GO:0005109)
0.0 0.0 GO:0005055 laminin receptor activity(GO:0005055)
0.0 0.7 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.0 0.6 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 0.1 GO:0043532 angiostatin binding(GO:0043532)
0.0 0.2 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.8 GO:0035064 methylated histone binding(GO:0035064)
0.0 0.2 GO:0031432 titin binding(GO:0031432)
0.0 0.3 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.0 3.1 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.1 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 5.0 ST G ALPHA S PATHWAY G alpha s Pathway
0.1 6.1 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.1 5.5 PID PI3KCI PATHWAY Class I PI3K signaling events
0.0 10.5 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.0 3.0 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 1.0 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 0.7 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.0 1.8 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 0.2 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling
0.0 0.8 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.0 2.3 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 2.8 ST INTEGRIN SIGNALING PATHWAY Integrin Signaling Pathway
0.0 1.4 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.0 0.4 PID ARF 3PATHWAY Arf1 pathway
0.0 1.5 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 0.9 PID FGF PATHWAY FGF signaling pathway
0.0 4.0 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 4.6 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 0.3 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.0 0.3 PID EPHA FWDPATHWAY EPHA forward signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 5.0 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
0.1 2.2 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.1 2.6 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.1 1.5 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.1 0.3 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.1 3.3 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.1 2.2 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.1 6.2 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.1 1.5 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.1 0.9 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.1 0.9 REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1 Genes involved in Signaling by activated point mutants of FGFR1
0.1 2.3 REACTOME AMINE COMPOUND SLC TRANSPORTERS Genes involved in Amine compound SLC transporters
0.1 1.1 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 2.1 REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.0 4.0 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 1.1 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 0.7 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 4.9 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 0.2 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.0 0.3 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0 0.8 REACTOME ADP SIGNALLING THROUGH P2RY12 Genes involved in ADP signalling through P2Y purinoceptor 12
0.0 0.5 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.8 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.0 0.4 REACTOME SIGNALING BY PDGF Genes involved in Signaling by PDGF
0.0 1.0 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 1.0 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 2.8 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 1.0 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.4 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.0 0.9 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 0.5 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.1 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 0.3 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.0 0.2 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.0 0.3 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)