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SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for KLF6

Z-value: 1.76

Motif logo

Transcription factors associated with KLF6

Gene Symbol Gene ID Gene Info
ENSG00000067082.10 Kruppel like factor 6

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
KLF6hg19_v2_chr10_-_3827417_38274730.769.7e-05Click!

Activity profile of KLF6 motif

Sorted Z-values of KLF6 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr11_+_57365150 7.95 ENST00000457869.1
ENST00000340687.6
ENST00000378323.4
ENST00000378324.2
ENST00000403558.1
serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
chr1_-_182361327 7.13 ENST00000331872.6
ENST00000311223.5
glutamate-ammonia ligase
chr1_-_6321035 7.03 ENST00000377893.2
G protein-coupled receptor 153
chr16_+_68679193 7.00 ENST00000581171.1
cadherin 3, type 1, P-cadherin (placental)
chr16_+_68678739 6.75 ENST00000264012.4
cadherin 3, type 1, P-cadherin (placental)
chr1_-_182360498 6.54 ENST00000417584.2
glutamate-ammonia ligase
chr16_+_68678892 6.50 ENST00000429102.2
cadherin 3, type 1, P-cadherin (placental)
chr1_-_182360918 6.34 ENST00000339526.4
glutamate-ammonia ligase
chr7_-_143105941 6.26 ENST00000275815.3
EPH receptor A1
chr3_+_50192499 5.90 ENST00000413852.1
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
chr3_+_50192457 5.62 ENST00000414301.1
ENST00000450338.1
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
chr3_+_50192537 5.50 ENST00000002829.3
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
chr5_+_137801160 4.22 ENST00000239938.4
early growth response 1
chr15_+_98503922 4.18 ENST00000268042.6
arrestin domain containing 4
chr3_+_50192833 4.06 ENST00000426511.1
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
chr21_-_28217721 3.85 ENST00000284984.3
ADAM metallopeptidase with thrombospondin type 1 motif, 1
chr15_+_41136216 3.65 ENST00000562057.1
ENST00000344051.4
serine peptidase inhibitor, Kunitz type 1
chr14_+_94640633 3.41 ENST00000304338.3
protein phosphatase 4, regulatory subunit 4
chr2_+_70142232 3.39 ENST00000540449.1
MAX dimerization protein 1
chr15_+_41136586 3.39 ENST00000431806.1
serine peptidase inhibitor, Kunitz type 1
chr1_+_43148059 3.38 ENST00000321358.7
ENST00000332220.6
Y box binding protein 1
chr22_+_31608219 3.30 ENST00000406516.1
ENST00000444929.2
ENST00000331728.4
LIM domain kinase 2
chr1_+_43148625 3.28 ENST00000436427.1
Y box binding protein 1
chr11_+_129939811 3.09 ENST00000345598.5
ENST00000338167.5
amyloid beta (A4) precursor-like protein 2
chr2_+_70142189 3.07 ENST00000264444.2
MAX dimerization protein 1
chr11_+_129939779 3.05 ENST00000533195.1
ENST00000533713.1
ENST00000528499.1
ENST00000539648.1
ENST00000263574.5
amyloid beta (A4) precursor-like protein 2
chr1_+_68150744 3.02 ENST00000370986.4
ENST00000370985.3
growth arrest and DNA-damage-inducible, alpha
chr14_+_94640671 2.90 ENST00000328839.3
protein phosphatase 4, regulatory subunit 4
chr11_-_94964354 2.87 ENST00000536441.1
sestrin 3
chr10_+_72972281 2.74 ENST00000335350.6
unc-5 homolog B (C. elegans)
chr10_-_25012597 2.54 ENST00000396432.2
Rho GTPase activating protein 21
chr3_-_113415441 2.53 ENST00000491165.1
ENST00000316407.4
KIAA2018
chr17_+_7341586 2.52 ENST00000575235.1
fibroblast growth factor 11
chr11_-_65640071 2.49 ENST00000526624.1
EGF containing fibulin-like extracellular matrix protein 2
chr11_+_64008525 2.48 ENST00000449942.2
FK506 binding protein 2, 13kDa
chr4_-_77819002 2.47 ENST00000334306.2
sosondowah ankyrin repeat domain family member B
chr15_+_41136369 2.43 ENST00000563656.1
serine peptidase inhibitor, Kunitz type 1
chr1_-_111746966 2.41 ENST00000369752.5
DENN/MADD domain containing 2D
chr15_-_74726283 2.36 ENST00000543145.2
semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group)
chr15_+_96873921 2.35 ENST00000394166.3
nuclear receptor subfamily 2, group F, member 2
chr1_-_156051789 2.34 ENST00000532414.2
mex-3 RNA binding family member A
chr4_-_36246060 2.32 ENST00000303965.4
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr2_-_220408430 2.29 ENST00000243776.6
chondroitin polymerizing factor
chr10_+_112631699 2.28 ENST00000444997.1
programmed cell death 4 (neoplastic transformation inhibitor)
chr11_-_94964210 2.24 ENST00000416495.2
ENST00000393234.1
sestrin 3
chr6_+_31588478 2.19 ENST00000376007.4
ENST00000376033.2
proline-rich coiled-coil 2A
chr12_-_54785074 2.18 ENST00000338010.5
ENST00000550774.1
zinc finger protein 385A
chr3_+_184032283 2.16 ENST00000346169.2
ENST00000414031.1
eukaryotic translation initiation factor 4 gamma, 1
chr1_+_202995611 2.13 ENST00000367240.2
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4
chr17_+_79008940 2.10 ENST00000392411.3
ENST00000575989.1
ENST00000321280.7
ENST00000428708.2
ENST00000575712.1
ENST00000575245.1
ENST00000435091.3
ENST00000321300.6
BAI1-associated protein 2
chr6_+_37787704 2.08 ENST00000474522.1
zinc finger, AN1-type domain 3
chr9_+_34989638 2.07 ENST00000453597.3
ENST00000335998.3
ENST00000312316.5
DnaJ (Hsp40) homolog, subfamily B, member 5
chr3_+_184032313 2.07 ENST00000392537.2
ENST00000444134.1
ENST00000450424.1
ENST00000421110.1
ENST00000382330.3
ENST00000426123.1
ENST00000350481.5
ENST00000455679.1
ENST00000440448.1
eukaryotic translation initiation factor 4 gamma, 1
chr6_+_37137939 2.06 ENST00000373509.5
pim-1 oncogene
chr6_+_44095347 2.06 ENST00000323267.6
transmembrane protein 63B
chr19_+_13049413 2.04 ENST00000316448.5
ENST00000588454.1
calreticulin
chr5_-_2751762 2.04 ENST00000302057.5
ENST00000382611.6
iroquois homeobox 2
chr19_-_49568311 1.98 ENST00000595857.1
ENST00000451356.2
neurotrophin 4
chr7_+_90225796 1.94 ENST00000380050.3
cyclin-dependent kinase 14
chr3_-_18486354 1.91 ENST00000493952.2
ENST00000440737.1
SATB homeobox 1
chr4_-_153456153 1.90 ENST00000603548.1
F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
chr4_+_89444961 1.89 ENST00000513325.1
HECT and RLD domain containing E3 ubiquitin protein ligase 3
chr1_-_221915418 1.88 ENST00000323825.3
ENST00000366899.3
dual specificity phosphatase 10
chr6_+_43739697 1.85 ENST00000230480.6
vascular endothelial growth factor A
chr19_+_10196981 1.84 ENST00000591813.1
chromosome 19 open reading frame 66
chr6_-_35656712 1.83 ENST00000357266.4
ENST00000542713.1
FK506 binding protein 5
chr6_-_33285505 1.81 ENST00000431845.2
zinc finger and BTB domain containing 22
chr1_-_113498616 1.80 ENST00000433570.4
ENST00000538576.1
ENST00000458229.1
solute carrier family 16 (monocarboxylate transporter), member 1
chr1_-_23670813 1.79 ENST00000374612.1
heterogeneous nuclear ribonucleoprotein R
chr22_+_35653445 1.75 ENST00000420166.1
ENST00000444518.2
ENST00000455359.1
ENST00000216106.5
HMG box domain containing 4
chr22_+_41777927 1.75 ENST00000266304.4
thyrotrophic embryonic factor
chr1_-_23670752 1.74 ENST00000302271.6
ENST00000426846.2
ENST00000427764.2
ENST00000606561.1
ENST00000374616.3
heterogeneous nuclear ribonucleoprotein R
chr10_-_75634219 1.74 ENST00000305762.7
calcium/calmodulin-dependent protein kinase II gamma
chr5_-_81046904 1.73 ENST00000515395.1
single-stranded DNA binding protein 2
chr12_-_54785054 1.73 ENST00000352268.6
ENST00000549962.1
zinc finger protein 385A
chr19_+_50084561 1.71 ENST00000246794.5
proline rich Gla (G-carboxyglutamic acid) 2
chr1_+_40506255 1.66 ENST00000421589.1
CAP, adenylate cyclase-associated protein 1 (yeast)
chr10_-_101380121 1.66 ENST00000370495.4
solute carrier family 25 (mitochondrial iron transporter), member 28
chr17_+_45771420 1.65 ENST00000578982.1
TBK1 binding protein 1
chr17_+_8339340 1.65 ENST00000580012.1
nudE neurodevelopment protein 1-like 1
chr1_-_154531095 1.64 ENST00000292211.4
ubiquitin-conjugating enzyme E2Q family member 1
chr6_+_33168189 1.63 ENST00000444757.1
solute carrier family 39 (zinc transporter), member 7
chr1_-_23670817 1.59 ENST00000478691.1
heterogeneous nuclear ribonucleoprotein R
chr8_-_57123815 1.59 ENST00000316981.3
ENST00000423799.2
ENST00000429357.2
pleiomorphic adenoma gene 1
chr6_-_35656685 1.56 ENST00000539068.1
ENST00000540787.1
FK506 binding protein 5
chr6_-_110501200 1.54 ENST00000392586.1
ENST00000419252.1
ENST00000392589.1
ENST00000392588.1
ENST00000359451.2
WAS protein family, member 1
chr11_+_64009072 1.53 ENST00000535135.1
ENST00000394540.3
FK506 binding protein 2, 13kDa
chr1_+_160175201 1.50 ENST00000368076.1
phosphoprotein enriched in astrocytes 15
chr10_-_75634326 1.49 ENST00000322635.3
ENST00000444854.2
ENST00000423381.1
ENST00000322680.3
ENST00000394762.2
calcium/calmodulin-dependent protein kinase II gamma
chr17_+_47572647 1.48 ENST00000172229.3
nerve growth factor receptor
chr12_+_56473628 1.48 ENST00000549282.1
ENST00000549061.1
ENST00000267101.3
v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3
chr7_+_143078652 1.46 ENST00000354434.4
ENST00000449423.2
zyxin
chr1_+_40506392 1.43 ENST00000414893.1
ENST00000414281.1
ENST00000420216.1
ENST00000372792.2
ENST00000372798.1
ENST00000340450.3
ENST00000372805.3
ENST00000435719.1
ENST00000427843.1
ENST00000417287.1
ENST00000424977.1
ENST00000446031.1
CAP, adenylate cyclase-associated protein 1 (yeast)
chr4_+_48343339 1.42 ENST00000264313.6
SLAIN motif family, member 2
chr1_+_160175117 1.41 ENST00000360472.4
phosphoprotein enriched in astrocytes 15
chr21_+_43639211 1.41 ENST00000450121.1
ENST00000398449.3
ENST00000361802.2
ATP-binding cassette, sub-family G (WHITE), member 1
chr19_+_7895074 1.40 ENST00000270530.4
ecotropic viral integration site 5-like
chr10_+_23983671 1.38 ENST00000376462.1
KIAA1217
chr11_-_118661588 1.38 ENST00000534980.1
ENST00000526070.2
DEAD (Asp-Glu-Ala-Asp) box helicase 6
chr1_-_226924980 1.37 ENST00000272117.3
inositol-trisphosphate 3-kinase B
chr17_-_47841485 1.36 ENST00000506156.1
ENST00000240364.2
family with sequence similarity 117, member A
chr12_-_50222187 1.35 ENST00000335999.6
NCK-associated protein 5-like
chr10_-_75634260 1.34 ENST00000372765.1
ENST00000351293.3
calcium/calmodulin-dependent protein kinase II gamma
chr20_+_60813535 1.34 ENST00000358053.2
ENST00000313733.3
ENST00000439951.2
oxysterol binding protein-like 2
chr17_+_48611853 1.34 ENST00000507709.1
ENST00000515126.1
ENST00000507467.1
epsin 3
chr6_+_31926857 1.33 ENST00000375394.2
ENST00000544581.1
superkiller viralicidic activity 2-like (S. cerevisiae)
chr1_-_113498943 1.33 ENST00000369626.3
solute carrier family 16 (monocarboxylate transporter), member 1
chr19_-_14629224 1.33 ENST00000254322.2
DnaJ (Hsp40) homolog, subfamily B, member 1
chr15_-_70388943 1.33 ENST00000559048.1
ENST00000560939.1
ENST00000440567.3
ENST00000557907.1
ENST00000558379.1
ENST00000451782.2
ENST00000559929.1
transducin-like enhancer of split 3 (E(sp1) homolog, Drosophila)
chr1_+_107682629 1.31 ENST00000370074.4
ENST00000370073.2
ENST00000370071.2
ENST00000542803.1
ENST00000370061.3
ENST00000370072.3
ENST00000370070.2
netrin G1
chr6_+_83777374 1.31 ENST00000349129.2
ENST00000237163.5
ENST00000536812.1
dopey family member 1
chr15_+_41136263 1.31 ENST00000568823.1
serine peptidase inhibitor, Kunitz type 1
chr17_-_42277203 1.29 ENST00000587097.1
ataxin 7-like 3
chr20_-_40247002 1.29 ENST00000373222.3
chromodomain helicase DNA binding protein 6
chr13_-_52027134 1.28 ENST00000311234.4
ENST00000425000.1
ENST00000463928.1
ENST00000442263.3
ENST00000398119.2
integrator complex subunit 6
chr7_-_129592471 1.27 ENST00000473814.2
ENST00000490974.1
ubiquitin-conjugating enzyme E2H
chr2_+_220299547 1.27 ENST00000312358.7
SPEG complex locus
chr14_+_21945335 1.27 ENST00000262709.3
ENST00000457430.2
ENST00000448790.2
TOX high mobility group box family member 4
chr10_-_103874692 1.26 ENST00000361198.5
LIM domain binding 1
chr1_-_156698181 1.26 ENST00000313146.6
interferon stimulated exonuclease gene 20kDa-like 2
chr12_+_57482665 1.25 ENST00000300131.3
NGFI-A binding protein 2 (EGR1 binding protein 2)
chr10_+_11060004 1.25 ENST00000542579.1
ENST00000399850.3
ENST00000417956.2
CUGBP, Elav-like family member 2
chr16_+_2563871 1.24 ENST00000330398.4
ENST00000568562.1
ENST00000569317.1
ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c
Uncharacterized protein
chr2_+_219081817 1.24 ENST00000315717.5
ENST00000420104.1
ENST00000295685.10
actin related protein 2/3 complex, subunit 2, 34kDa
chr12_+_14518598 1.22 ENST00000261168.4
ENST00000538511.1
ENST00000545723.1
ENST00000543189.1
ENST00000536444.1
activating transcription factor 7 interacting protein
chr5_-_81046922 1.22 ENST00000514493.1
ENST00000320672.4
single-stranded DNA binding protein 2
chr11_+_65686952 1.21 ENST00000527119.1
DR1-associated protein 1 (negative cofactor 2 alpha)
chrX_+_21959108 1.21 ENST00000457085.1
spermine synthase
chr6_-_110500905 1.21 ENST00000392587.2
WAS protein family, member 1
chr11_+_68228186 1.20 ENST00000393799.2
ENST00000393800.2
ENST00000528635.1
ENST00000533127.1
ENST00000529907.1
ENST00000529344.1
ENST00000534534.1
ENST00000524845.1
ENST00000265637.4
ENST00000524904.1
ENST00000393801.3
ENST00000265636.5
ENST00000529710.1
protein phosphatase 6, regulatory subunit 3
chr15_-_43882353 1.20 ENST00000453080.1
ENST00000360301.4
ENST00000360135.4
ENST00000417085.1
ENST00000431962.1
ENST00000334933.4
ENST00000381879.4
ENST00000420765.1
diphosphoinositol pentakisphosphate kinase 1
chr6_+_44095263 1.20 ENST00000532634.1
transmembrane protein 63B
chr14_+_23791159 1.20 ENST00000557702.1
poly(A) binding protein, nuclear 1
chr10_+_45869652 1.18 ENST00000542434.1
ENST00000374391.2
arachidonate 5-lipoxygenase
chr9_-_34376851 1.18 ENST00000297625.7
KIAA1161
chr1_-_156698591 1.16 ENST00000368219.1
interferon stimulated exonuclease gene 20kDa-like 2
chr3_+_133293278 1.16 ENST00000508481.1
ENST00000420115.2
ENST00000504867.1
ENST00000507408.1
ENST00000511392.1
ENST00000515421.1
CDV3 homolog (mouse)
chr17_+_42081914 1.15 ENST00000293404.3
ENST00000589767.1
N-acetylglutamate synthase
chr7_+_70229899 1.15 ENST00000443672.1
autism susceptibility candidate 2
chr20_+_35201993 1.14 ENST00000373872.4
TGFB-induced factor homeobox 2
chr12_-_49351148 1.14 ENST00000398092.4
ENST00000539611.1
ADP-ribosylation factor 3
ADP-ribosylation factor 3
chr18_-_51751132 1.14 ENST00000256429.3
methyl-CpG binding domain protein 2
chr22_+_38004723 1.13 ENST00000381756.5
golgi-associated, gamma adaptin ear containing, ARF binding protein 1
chr22_+_38004832 1.13 ENST00000405147.3
ENST00000429218.1
ENST00000325180.8
ENST00000337437.4
golgi-associated, gamma adaptin ear containing, ARF binding protein 1
chr4_+_26862313 1.13 ENST00000467087.1
ENST00000382009.3
ENST00000237364.5
stromal interaction molecule 2
chr1_+_27022839 1.12 ENST00000457599.2
AT rich interactive domain 1A (SWI-like)
chr4_+_144258021 1.12 ENST00000262994.4
GRB2-associated binding protein 1
chr19_+_1249869 1.12 ENST00000591446.2
midnolin
chr10_+_11059826 1.11 ENST00000450189.1
CUGBP, Elav-like family member 2
chr12_-_80328700 1.11 ENST00000550107.1
protein phosphatase 1, regulatory subunit 12A
chr12_+_112451120 1.10 ENST00000261735.3
ENST00000455836.1
endoplasmic reticulum protein 29
chr1_+_112939121 1.10 ENST00000441739.1
CTTNBP2 N-terminal like
chr3_+_49209023 1.10 ENST00000332780.2
kelch domain containing 8B
chr1_+_112938803 1.09 ENST00000271277.6
CTTNBP2 N-terminal like
chr8_+_57124245 1.09 ENST00000521831.1
ENST00000355315.3
ENST00000303759.3
ENST00000517636.1
ENST00000517933.1
ENST00000518801.1
ENST00000523975.1
ENST00000396723.5
ENST00000523061.1
ENST00000521524.1
coiled-coil-helix-coiled-coil-helix domain containing 7
chr3_+_133292759 1.07 ENST00000431519.2
CDV3 homolog (mouse)
chr11_-_65429891 1.07 ENST00000527874.1
v-rel avian reticuloendotheliosis viral oncogene homolog A
chr4_-_103789996 1.07 ENST00000508238.1
ubiquitin-conjugating enzyme E2D 3
chr1_-_22263790 1.07 ENST00000374695.3
heparan sulfate proteoglycan 2
chr5_+_67511524 1.07 ENST00000521381.1
ENST00000521657.1
phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
chr6_-_150039170 1.07 ENST00000458696.2
ENST00000392273.3
large tumor suppressor kinase 1
chr6_-_137113604 1.06 ENST00000359015.4
mitogen-activated protein kinase kinase kinase 5
chr7_+_143079000 1.06 ENST00000392910.2
zyxin
chr7_+_30174668 1.06 ENST00000415604.1
maturin, neural progenitor differentiation regulator homolog (Xenopus)
chr1_+_6845578 1.06 ENST00000467404.2
ENST00000439411.2
calmodulin binding transcription activator 1
chr12_-_49351228 1.05 ENST00000541959.1
ENST00000447318.2
ADP-ribosylation factor 3
chr21_-_40720995 1.05 ENST00000380749.5
high mobility group nucleosome binding domain 1
chr5_+_40679584 1.04 ENST00000302472.3
prostaglandin E receptor 4 (subtype EP4)
chr5_-_176900610 1.04 ENST00000477391.2
ENST00000393565.1
ENST00000309007.5
drebrin 1
chr20_+_35201857 1.03 ENST00000373874.2
TGFB-induced factor homeobox 2
chr6_-_143266297 1.03 ENST00000367603.2
human immunodeficiency virus type I enhancer binding protein 2
chr5_+_34929677 1.03 ENST00000342382.4
ENST00000382021.2
ENST00000303525.7
DnaJ (Hsp40) homolog, subfamily C, member 21
chr1_-_234745234 1.03 ENST00000366610.3
ENST00000366609.3
interferon regulatory factor 2 binding protein 2
chr16_-_30134441 1.02 ENST00000395200.1
mitogen-activated protein kinase 3
chr6_+_21593972 1.02 ENST00000244745.1
ENST00000543472.1
SRY (sex determining region Y)-box 4
chr1_+_33219592 1.02 ENST00000373481.3
KIAA1522
chr18_-_23670546 1.01 ENST00000542743.1
ENST00000545952.1
ENST00000539849.1
ENST00000415083.2
synovial sarcoma translocation, chromosome 18
chr12_-_31479107 1.01 ENST00000542983.1
family with sequence similarity 60, member A
chr17_+_4736627 1.00 ENST00000355280.6
ENST00000347992.7
misshapen-like kinase 1
chr11_-_2160180 1.00 ENST00000381406.4
insulin-like growth factor 2 (somatomedin A)
chr12_+_118814185 1.00 ENST00000543473.1
suppressor of defective silencing 3 homolog (S. cerevisiae)
chr1_-_91487806 0.99 ENST00000361321.5
zinc finger protein 644
chr5_+_60628074 0.98 ENST00000252744.5
zinc finger, SWIM-type containing 6
chr15_+_44084040 0.98 ENST00000249786.4
small EDRK-rich factor 2
chr1_+_160175166 0.98 ENST00000368077.1
phosphoprotein enriched in astrocytes 15
chr14_-_73925225 0.98 ENST00000356296.4
ENST00000355058.3
ENST00000359560.3
ENST00000557597.1
ENST00000554394.1
ENST00000555238.1
ENST00000535282.1
ENST00000555987.1
ENST00000555394.1
ENST00000554546.1
numb homolog (Drosophila)
chr10_+_76586348 0.98 ENST00000372724.1
ENST00000287239.4
ENST00000372714.1
K(lysine) acetyltransferase 6B
chr16_+_67465016 0.98 ENST00000326152.5
hydroxysteroid (11-beta) dehydrogenase 2
chrX_+_64887512 0.98 ENST00000360270.5
moesin
chr16_-_30102547 0.97 ENST00000279386.2
T-box 6
chr19_+_532049 0.97 ENST00000606136.1
cell division cycle 34
chr14_+_23790655 0.97 ENST00000397276.2
poly(A) binding protein, nuclear 1
chrX_+_69674943 0.96 ENST00000542398.1
discs, large homolog 3 (Drosophila)
chr2_+_159313452 0.96 ENST00000389757.3
ENST00000389759.3
plakophilin 4
chr11_-_94706705 0.96 ENST00000279839.6
CWC15 spliceosome-associated protein homolog (S. cerevisiae)
chr3_-_47205457 0.94 ENST00000409792.3
SET domain containing 2
chr1_+_40839369 0.94 ENST00000372718.3
small ArfGAP2
chr3_+_184032419 0.93 ENST00000352767.3
ENST00000427141.2
eukaryotic translation initiation factor 4 gamma, 1
chr1_+_117910047 0.93 ENST00000356554.3
mannosidase, alpha, class 1A, member 2
chr1_-_155243235 0.93 ENST00000355560.4
ENST00000368361.4
CDC-like kinase 2

Network of associatons between targets according to the STRING database.

First level regulatory network of KLF6

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
5.1 20.2 GO:1902910 regulation of monophenol monooxygenase activity(GO:0032771) positive regulation of monophenol monooxygenase activity(GO:0032773) negative regulation of catagen(GO:0051796) regulation of hair cycle by canonical Wnt signaling pathway(GO:0060901) positive regulation of melanosome transport(GO:1902910)
5.0 20.0 GO:0006542 glutamine biosynthetic process(GO:0006542)
1.5 21.1 GO:1901166 trunk segmentation(GO:0035290) trunk neural crest cell migration(GO:0036484) ventral trunk neural crest cell migration(GO:0036486) neural crest cell migration involved in autonomic nervous system development(GO:1901166)
1.4 4.2 GO:0050720 regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362) interleukin-1 beta biosynthetic process(GO:0050720)
1.0 3.1 GO:0015728 mevalonate transport(GO:0015728) behavioral response to nutrient(GO:0051780)
1.0 3.0 GO:1904247 positive regulation of polynucleotide adenylyltransferase activity(GO:1904247)
1.0 1.0 GO:0014043 negative regulation of neuron maturation(GO:0014043)
0.8 2.3 GO:1904761 negative regulation of myofibroblast differentiation(GO:1904761)
0.7 7.9 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.7 2.0 GO:0061193 sensory organ boundary specification(GO:0008052) formation of organ boundary(GO:0010160) taste bud development(GO:0061193)
0.6 1.8 GO:0038190 neuropilin signaling pathway(GO:0038189) VEGF-activated neuropilin signaling pathway(GO:0038190) positive regulation of retinal ganglion cell axon guidance(GO:1902336) regulation of protein kinase D signaling(GO:1903570) positive regulation of protein kinase D signaling(GO:1903572)
0.6 1.8 GO:2000657 regulation of apolipoprotein binding(GO:2000656) negative regulation of apolipoprotein binding(GO:2000657)
0.6 2.4 GO:0009956 radial pattern formation(GO:0009956)
0.6 3.9 GO:1902162 mRNA localization resulting in posttranscriptional regulation of gene expression(GO:0010609) regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902162) positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902164)
0.6 1.7 GO:0003408 optic cup formation involved in camera-type eye development(GO:0003408)
0.6 6.7 GO:1903608 protein localization to cytoplasmic stress granule(GO:1903608)
0.6 1.7 GO:0048250 mitochondrial iron ion transport(GO:0048250)
0.5 2.0 GO:0072086 specification of loop of Henle identity(GO:0072086) pattern specification involved in metanephros development(GO:0072268)
0.5 1.4 GO:0055099 response to high density lipoprotein particle(GO:0055099)
0.5 2.3 GO:0008050 female courtship behavior(GO:0008050)
0.4 1.2 GO:0023016 signal transduction by trans-phosphorylation(GO:0023016)
0.4 1.9 GO:2000639 regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
0.4 1.9 GO:0060266 negative regulation of respiratory burst involved in inflammatory response(GO:0060266)
0.4 1.9 GO:0030862 positive regulation of polarized epithelial cell differentiation(GO:0030862)
0.4 1.1 GO:0035508 positive regulation of myosin-light-chain-phosphatase activity(GO:0035508)
0.4 1.5 GO:0031455 glycine betaine biosynthetic process from choline(GO:0019285) glycine betaine metabolic process(GO:0031455) glycine betaine biosynthetic process(GO:0031456)
0.4 1.1 GO:0006117 acetaldehyde metabolic process(GO:0006117)
0.3 1.0 GO:2000417 negative regulation of eosinophil migration(GO:2000417)
0.3 5.2 GO:0002191 cap-dependent translational initiation(GO:0002191)
0.3 1.4 GO:0019072 viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
0.3 2.4 GO:0051684 maintenance of Golgi location(GO:0051684)
0.3 2.7 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.3 2.0 GO:0002501 peptide antigen assembly with MHC protein complex(GO:0002501)
0.3 1.7 GO:1904693 midbrain morphogenesis(GO:1904693)
0.3 0.9 GO:0097198 histone H3-K36 trimethylation(GO:0097198)
0.3 1.5 GO:0001827 inner cell mass cell fate commitment(GO:0001827) inner cell mass cellular morphogenesis(GO:0001828)
0.3 5.1 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.3 1.8 GO:0016480 negative regulation of transcription from RNA polymerase III promoter(GO:0016480)
0.3 1.1 GO:0098582 innate vocalization behavior(GO:0098582)
0.3 0.9 GO:0044830 modulation by host of viral RNA genome replication(GO:0044830) positive regulation of intracellular transport of viral material(GO:1901254)
0.3 0.8 GO:2000820 negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000820)
0.3 1.0 GO:0035905 N-terminal peptidyl-lysine acetylation(GO:0018076) ascending aorta development(GO:0035905) ascending aorta morphogenesis(GO:0035910)
0.3 0.8 GO:1900126 negative regulation of hyaluronan biosynthetic process(GO:1900126)
0.3 1.5 GO:0036518 chemorepulsion of dopaminergic neuron axon(GO:0036518)
0.2 0.7 GO:2000118 regulation of sodium-dependent phosphate transport(GO:2000118)
0.2 2.7 GO:1901341 activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.2 0.9 GO:0006597 spermine biosynthetic process(GO:0006597)
0.2 2.1 GO:1905232 cellular response to L-glutamate(GO:1905232)
0.2 0.7 GO:1903526 negative regulation of membrane tubulation(GO:1903526)
0.2 1.9 GO:0045059 positive thymic T cell selection(GO:0045059)
0.2 3.9 GO:0046325 negative regulation of glucose import(GO:0046325)
0.2 1.1 GO:0006015 5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
0.2 6.3 GO:0032515 negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.2 10.3 GO:2000178 negative regulation of neural precursor cell proliferation(GO:2000178)
0.2 1.1 GO:0043335 protein unfolding(GO:0043335)
0.2 3.9 GO:0001542 ovulation from ovarian follicle(GO:0001542)
0.2 0.8 GO:0036269 swimming behavior(GO:0036269)
0.2 0.8 GO:1904499 glial cell fate determination(GO:0007403) negative regulation of mitotic cell cycle, embryonic(GO:0045976) canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation(GO:0061324) regulation of chromatin-mediated maintenance of transcription(GO:1904499) positive regulation of chromatin-mediated maintenance of transcription(GO:1904501) regulation of euchromatin binding(GO:1904793)
0.2 1.1 GO:1903300 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.2 1.3 GO:0046985 positive regulation of hemoglobin biosynthetic process(GO:0046985)
0.2 1.4 GO:0090038 negative regulation of protein kinase C signaling(GO:0090038)
0.2 0.5 GO:0072034 primary prostatic bud elongation(GO:0060516) bronchus cartilage development(GO:0060532) common bile duct development(GO:0061009) lung smooth muscle development(GO:0061145) renal vesicle induction(GO:0072034)
0.2 1.8 GO:1901314 negative regulation of histone ubiquitination(GO:0033183) progesterone receptor signaling pathway(GO:0050847) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315)
0.2 1.2 GO:2001034 positive regulation of double-strand break repair via nonhomologous end joining(GO:2001034)
0.2 1.9 GO:0036091 positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0036091)
0.2 1.0 GO:0010643 cell communication by chemical coupling(GO:0010643)
0.2 0.5 GO:2000301 negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.2 0.5 GO:0086098 angiotensin-activated signaling pathway involved in heart process(GO:0086098) negative regulation of peptidyl-tyrosine autophosphorylation(GO:1900085) negative regulation of inward rectifier potassium channel activity(GO:1903609)
0.2 1.7 GO:0048680 positive regulation of axon regeneration(GO:0048680)
0.2 1.3 GO:0090166 Golgi disassembly(GO:0090166) spindle assembly involved in meiosis(GO:0090306)
0.2 1.0 GO:0022614 membrane to membrane docking(GO:0022614)
0.2 5.5 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.2 1.3 GO:0003084 positive regulation of systemic arterial blood pressure(GO:0003084)
0.2 4.6 GO:1901897 regulation of relaxation of cardiac muscle(GO:1901897)
0.2 2.0 GO:0070561 vitamin D receptor signaling pathway(GO:0070561)
0.2 0.5 GO:0035625 epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway(GO:0035625)
0.1 5.9 GO:0061157 mRNA destabilization(GO:0061157)
0.1 0.6 GO:0051088 PMA-inducible membrane protein ectodomain proteolysis(GO:0051088)
0.1 1.2 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.1 0.4 GO:0035964 COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.1 0.9 GO:1904381 Golgi apparatus mannose trimming(GO:1904381)
0.1 7.4 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.1 0.5 GO:0061030 epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030)
0.1 0.4 GO:0045799 negative regulation of nucleobase-containing compound transport(GO:0032240) positive regulation of chromatin assembly or disassembly(GO:0045799) negative regulation of RNA export from nucleus(GO:0046832)
0.1 0.7 GO:0060385 axonogenesis involved in innervation(GO:0060385)
0.1 1.2 GO:2001300 lipoxin metabolic process(GO:2001300)
0.1 1.6 GO:0070459 prolactin secretion(GO:0070459)
0.1 0.1 GO:0032707 negative regulation of interleukin-23 production(GO:0032707)
0.1 0.3 GO:0040040 thermosensory behavior(GO:0040040)
0.1 1.2 GO:0006526 arginine biosynthetic process(GO:0006526)
0.1 0.6 GO:1901675 negative regulation of histone H3-K27 acetylation(GO:1901675)
0.1 0.4 GO:0035616 histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.1 1.3 GO:0034427 nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5'(GO:0034427)
0.1 1.4 GO:1901409 positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.1 2.4 GO:0060907 positive regulation of macrophage cytokine production(GO:0060907)
0.1 0.5 GO:0097368 establishment of Sertoli cell barrier(GO:0097368)
0.1 1.0 GO:2000467 positive regulation of glycogen (starch) synthase activity(GO:2000467)
0.1 1.4 GO:0048706 embryonic skeletal system development(GO:0048706)
0.1 0.9 GO:0040032 post-embryonic body morphogenesis(GO:0040032)
0.1 1.4 GO:0048227 plasma membrane to endosome transport(GO:0048227)
0.1 0.1 GO:0097374 sensory neuron axon guidance(GO:0097374)
0.1 0.8 GO:0021684 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.1 0.5 GO:0051944 glial cell-derived neurotrophic factor secretion(GO:0044467) positive regulation of neurotransmitter uptake(GO:0051582) positive regulation of dopamine uptake involved in synaptic transmission(GO:0051586) positive regulation of catecholamine uptake involved in synaptic transmission(GO:0051944) negative regulation of dopamine receptor signaling pathway(GO:0060160) regulation of locomotion involved in locomotory behavior(GO:0090325) regulation of glial cell-derived neurotrophic factor secretion(GO:1900166) positive regulation of glial cell-derived neurotrophic factor secretion(GO:1900168)
0.1 0.5 GO:1903588 negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903588)
0.1 0.5 GO:0000255 allantoin metabolic process(GO:0000255)
0.1 1.4 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)
0.1 1.9 GO:0006020 inositol metabolic process(GO:0006020)
0.1 0.3 GO:0033484 nitric oxide homeostasis(GO:0033484)
0.1 1.0 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.1 0.8 GO:0070544 histone H3-K36 demethylation(GO:0070544)
0.1 0.8 GO:0050957 equilibrioception(GO:0050957)
0.1 2.2 GO:0038092 nodal signaling pathway(GO:0038092)
0.1 1.6 GO:0060252 positive regulation of glial cell proliferation(GO:0060252)
0.1 0.3 GO:0060434 bronchus morphogenesis(GO:0060434)
0.1 0.3 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.1 0.8 GO:0006931 substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.1 0.5 GO:0098728 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
0.1 0.6 GO:0016578 histone deubiquitination(GO:0016578)
0.1 0.5 GO:0034165 positive regulation of toll-like receptor 9 signaling pathway(GO:0034165)
0.1 1.3 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.1 1.6 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.1 0.9 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.1 1.0 GO:0030091 protein repair(GO:0030091)
0.1 6.9 GO:0051496 positive regulation of stress fiber assembly(GO:0051496)
0.1 0.5 GO:0033159 negative regulation of protein import into nucleus, translocation(GO:0033159)
0.1 1.4 GO:1902018 negative regulation of cilium assembly(GO:1902018)
0.1 0.4 GO:1901097 negative regulation of autophagosome maturation(GO:1901097)
0.1 1.6 GO:0000183 chromatin silencing at rDNA(GO:0000183)
0.1 1.4 GO:0033235 positive regulation of protein sumoylation(GO:0033235)
0.1 0.4 GO:0090283 regulation of protein glycosylation in Golgi(GO:0090283)
0.1 0.2 GO:0090222 centrosome-templated microtubule nucleation(GO:0090222)
0.1 1.0 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951) positive regulation of inclusion body assembly(GO:0090261)
0.1 0.3 GO:0003415 chondrocyte hypertrophy(GO:0003415)
0.1 1.0 GO:0033182 regulation of histone ubiquitination(GO:0033182)
0.1 0.5 GO:0042476 odontogenesis(GO:0042476)
0.1 0.3 GO:0060741 prostate gland stromal morphogenesis(GO:0060741)
0.1 4.0 GO:1901998 toxin transport(GO:1901998)
0.1 1.1 GO:0010666 positive regulation of striated muscle cell apoptotic process(GO:0010663) positive regulation of cardiac muscle cell apoptotic process(GO:0010666)
0.1 1.2 GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.1 3.1 GO:0007190 activation of adenylate cyclase activity(GO:0007190)
0.1 1.3 GO:0016180 snRNA processing(GO:0016180)
0.1 0.5 GO:1901187 regulation of ephrin receptor signaling pathway(GO:1901187)
0.1 1.2 GO:0043982 histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
0.1 0.6 GO:0060059 embryonic retina morphogenesis in camera-type eye(GO:0060059)
0.1 0.6 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
0.1 0.9 GO:0043653 mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.1 1.5 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.1 0.3 GO:0060028 somatic muscle development(GO:0007525) non-canonical Wnt signaling pathway via MAPK cascade(GO:0038030) non-canonical Wnt signaling pathway via JNK cascade(GO:0038031) convergent extension involved in axis elongation(GO:0060028) axis elongation involved in somitogenesis(GO:0090245)
0.1 0.3 GO:0002019 regulation of renal output by angiotensin(GO:0002019) negative regulation of gap junction assembly(GO:1903597)
0.1 3.2 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.1 0.4 GO:0071603 endothelial cell-cell adhesion(GO:0071603)
0.1 2.4 GO:0006376 mRNA splice site selection(GO:0006376)
0.1 0.7 GO:0080182 histone H3-K4 trimethylation(GO:0080182)
0.1 1.3 GO:0006895 Golgi to endosome transport(GO:0006895)
0.1 0.3 GO:1903299 regulation of glucokinase activity(GO:0033131) regulation of hexokinase activity(GO:1903299)
0.0 0.7 GO:0072104 glomerulus vasculature morphogenesis(GO:0072103) glomerular capillary formation(GO:0072104)
0.0 0.2 GO:0090170 regulation of Golgi inheritance(GO:0090170)
0.0 0.2 GO:0033629 negative regulation of cell adhesion mediated by integrin(GO:0033629)
0.0 0.5 GO:1902961 positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902961) positive regulation of aspartic-type peptidase activity(GO:1905247)
0.0 1.7 GO:0048009 insulin-like growth factor receptor signaling pathway(GO:0048009)
0.0 0.8 GO:0098828 positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.0 0.2 GO:0014826 vein smooth muscle contraction(GO:0014826)
0.0 1.0 GO:0097150 neuronal stem cell population maintenance(GO:0097150)
0.0 0.5 GO:0036089 cleavage furrow formation(GO:0036089)
0.0 1.2 GO:0045898 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.0 0.4 GO:0097091 synaptic vesicle clustering(GO:0097091)
0.0 1.2 GO:0043666 regulation of phosphoprotein phosphatase activity(GO:0043666)
0.0 2.1 GO:0090503 RNA phosphodiester bond hydrolysis, exonucleolytic(GO:0090503)
0.0 1.8 GO:0007020 microtubule nucleation(GO:0007020)
0.0 0.9 GO:0001829 trophectodermal cell differentiation(GO:0001829)
0.0 0.5 GO:0032782 bile acid secretion(GO:0032782)
0.0 0.2 GO:1903593 regulation of histamine secretion by mast cell(GO:1903593)
0.0 0.6 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.0 0.8 GO:0007252 I-kappaB phosphorylation(GO:0007252)
0.0 1.0 GO:0003334 keratinocyte development(GO:0003334)
0.0 0.3 GO:0015870 acetylcholine transport(GO:0015870)
0.0 1.6 GO:0006882 cellular zinc ion homeostasis(GO:0006882)
0.0 0.1 GO:0044828 negative regulation by host of viral genome replication(GO:0044828)
0.0 0.2 GO:0046108 uridine metabolic process(GO:0046108)
0.0 1.2 GO:0035728 response to hepatocyte growth factor(GO:0035728)
0.0 0.7 GO:0031507 heterochromatin assembly(GO:0031507)
0.0 0.3 GO:0038165 oncostatin-M-mediated signaling pathway(GO:0038165)
0.0 0.8 GO:2000146 negative regulation of locomotion(GO:0040013) negative regulation of cell motility(GO:2000146)
0.0 1.5 GO:2001222 regulation of neuron migration(GO:2001222)
0.0 0.4 GO:0006013 mannose metabolic process(GO:0006013)
0.0 0.1 GO:0006452 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.0 0.2 GO:0072674 multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675)
0.0 1.6 GO:0050435 beta-amyloid metabolic process(GO:0050435)
0.0 0.2 GO:0014005 microglia differentiation(GO:0014004) microglia development(GO:0014005)
0.0 0.5 GO:0006776 vitamin A metabolic process(GO:0006776)
0.0 0.9 GO:0097320 membrane tubulation(GO:0097320)
0.0 0.7 GO:0001953 negative regulation of cell-matrix adhesion(GO:0001953)
0.0 0.4 GO:0043306 positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of mast cell degranulation(GO:0043306)
0.0 0.4 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.0 0.3 GO:0070345 negative regulation of fat cell proliferation(GO:0070345)
0.0 0.9 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.0 0.5 GO:0046887 positive regulation of hormone secretion(GO:0046887)
0.0 1.9 GO:1904837 beta-catenin-TCF complex assembly(GO:1904837)
0.0 1.2 GO:1900026 positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
0.0 2.6 GO:0042795 snRNA transcription(GO:0009301) snRNA transcription from RNA polymerase II promoter(GO:0042795)
0.0 0.6 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.0 2.5 GO:0043149 contractile actin filament bundle assembly(GO:0030038) stress fiber assembly(GO:0043149)
0.0 0.4 GO:0010571 positive regulation of nuclear cell cycle DNA replication(GO:0010571)
0.0 0.3 GO:0060999 positive regulation of dendritic spine development(GO:0060999)
0.0 5.4 GO:0002576 platelet degranulation(GO:0002576)
0.0 3.4 GO:0051443 positive regulation of ubiquitin-protein transferase activity(GO:0051443)
0.0 0.2 GO:0070120 ciliary neurotrophic factor-mediated signaling pathway(GO:0070120)
0.0 0.2 GO:1900364 negative regulation of mRNA polyadenylation(GO:1900364)
0.0 0.1 GO:0032223 negative regulation of synaptic transmission, cholinergic(GO:0032223) neurotransmitter receptor biosynthetic process(GO:0045212)
0.0 0.8 GO:0007194 negative regulation of adenylate cyclase activity(GO:0007194)
0.0 1.0 GO:0006783 heme biosynthetic process(GO:0006783)
0.0 1.3 GO:0006699 bile acid biosynthetic process(GO:0006699)
0.0 0.4 GO:1902894 negative regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902894)
0.0 0.2 GO:0051968 positive regulation of synaptic transmission, glutamatergic(GO:0051968)
0.0 0.2 GO:0021800 cerebral cortex tangential migration(GO:0021800)
0.0 0.5 GO:0032786 positive regulation of DNA-templated transcription, elongation(GO:0032786)
0.0 0.2 GO:0010591 regulation of lamellipodium assembly(GO:0010591)
0.0 0.4 GO:0045475 locomotor rhythm(GO:0045475)
0.0 0.2 GO:0070537 histone H2A K63-linked deubiquitination(GO:0070537)
0.0 1.2 GO:0051057 positive regulation of small GTPase mediated signal transduction(GO:0051057)
0.0 0.6 GO:0045672 positive regulation of osteoclast differentiation(GO:0045672)
0.0 0.1 GO:0030167 proteoglycan catabolic process(GO:0030167) heparan sulfate proteoglycan catabolic process(GO:0030200)
0.0 0.8 GO:0090383 phagosome acidification(GO:0090383)
0.0 0.6 GO:2000272 negative regulation of receptor activity(GO:2000272)
0.0 0.3 GO:0015074 DNA integration(GO:0015074) establishment of integrated proviral latency(GO:0075713)
0.0 0.2 GO:0042472 inner ear morphogenesis(GO:0042472)
0.0 0.4 GO:0010827 regulation of glucose transport(GO:0010827) regulation of glucose import(GO:0046324)
0.0 0.1 GO:0042998 positive regulation of Golgi to plasma membrane protein transport(GO:0042998)
0.0 0.9 GO:0051291 protein heterooligomerization(GO:0051291)
0.0 0.3 GO:0002456 T cell mediated immunity(GO:0002456)
0.0 0.1 GO:0010587 miRNA catabolic process(GO:0010587)
0.0 0.4 GO:0045723 positive regulation of fatty acid biosynthetic process(GO:0045723)
0.0 2.1 GO:0006501 C-terminal protein lipidation(GO:0006501)
0.0 0.2 GO:0031119 tRNA pseudouridine synthesis(GO:0031119)
0.0 2.2 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.0 0.2 GO:0045669 positive regulation of osteoblast differentiation(GO:0045669)
0.0 0.3 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.0 0.6 GO:0006656 phosphatidylcholine biosynthetic process(GO:0006656)
0.0 0.5 GO:0036150 phosphatidylserine acyl-chain remodeling(GO:0036150)
0.0 0.1 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.0 1.9 GO:0001523 retinoid metabolic process(GO:0001523)
0.0 0.2 GO:0030497 fatty acid elongation(GO:0030497)
0.0 0.1 GO:0070164 negative regulation of adiponectin secretion(GO:0070164)
0.0 1.1 GO:0050885 neuromuscular process controlling balance(GO:0050885)
0.0 1.3 GO:0045071 negative regulation of viral genome replication(GO:0045071)
0.0 0.1 GO:0060689 cell differentiation involved in salivary gland development(GO:0060689)
0.0 0.3 GO:0018027 peptidyl-lysine dimethylation(GO:0018027)
0.0 0.9 GO:0046626 regulation of insulin receptor signaling pathway(GO:0046626)
0.0 0.2 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.0 0.2 GO:0042347 negative regulation of NF-kappaB import into nucleus(GO:0042347)
0.0 0.3 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.0 0.3 GO:0000042 protein targeting to Golgi(GO:0000042)
0.0 0.5 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.0 0.6 GO:0007019 microtubule depolymerization(GO:0007019)
0.0 1.0 GO:0071260 cellular response to mechanical stimulus(GO:0071260)
0.0 0.7 GO:0046686 response to cadmium ion(GO:0046686)
0.0 0.1 GO:0034378 chylomicron assembly(GO:0034378)
0.0 1.1 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 0.1 GO:0042482 positive regulation of odontogenesis(GO:0042482) positive regulation of tooth mineralization(GO:0070172)
0.0 0.4 GO:0006884 cell volume homeostasis(GO:0006884)
0.0 0.2 GO:0043984 histone H4-K16 acetylation(GO:0043984)
0.0 0.6 GO:0043171 peptide catabolic process(GO:0043171)
0.0 0.1 GO:0032098 regulation of appetite(GO:0032098)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 20.9 GO:0097386 glial cell projection(GO:0097386)
0.7 6.7 GO:0071204 histone pre-mRNA 3'end processing complex(GO:0071204)
0.4 1.2 GO:0036195 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.4 1.1 GO:0035525 NF-kappaB p50/p65 complex(GO:0035525)
0.3 1.3 GO:0055087 Ski complex(GO:0055087)
0.3 1.7 GO:0060053 neurofilament cytoskeleton(GO:0060053)
0.3 1.9 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.3 0.9 GO:0031372 UBC13-MMS2 complex(GO:0031372)
0.3 5.1 GO:0061700 GATOR2 complex(GO:0061700)
0.3 1.9 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.2 2.0 GO:0042824 MHC class I peptide loading complex(GO:0042824)
0.2 1.1 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
0.2 0.8 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
0.2 5.2 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.2 3.4 GO:0042405 nuclear inclusion body(GO:0042405)
0.2 0.5 GO:0070195 growth hormone receptor complex(GO:0070195)
0.2 1.8 GO:0016589 NURF complex(GO:0016589)
0.2 1.9 GO:0005641 nuclear envelope lumen(GO:0005641)
0.1 6.1 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.1 1.8 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.1 1.1 GO:1990578 perinuclear endoplasmic reticulum membrane(GO:1990578)
0.1 3.6 GO:0016580 Sin3 complex(GO:0016580)
0.1 0.8 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.1 2.8 GO:0031143 pseudopodium(GO:0031143)
0.1 0.3 GO:0005900 oncostatin-M receptor complex(GO:0005900)
0.1 0.4 GO:0071664 catenin-TCF7L2 complex(GO:0071664) gamma-catenin-TCF7L2 complex(GO:0071665)
0.1 1.4 GO:0001520 outer dense fiber(GO:0001520)
0.1 0.8 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.1 1.2 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.1 1.5 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.1 1.1 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.1 15.4 GO:0005913 cell-cell adherens junction(GO:0005913)
0.1 1.1 GO:0000137 Golgi cis cisterna(GO:0000137)
0.1 10.3 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.1 0.4 GO:0005797 Golgi medial cisterna(GO:0005797)
0.1 0.4 GO:0098837 postsynaptic recycling endosome(GO:0098837)
0.1 0.4 GO:0014802 terminal cisterna(GO:0014802)
0.1 0.7 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.1 0.9 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.1 2.4 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.1 1.1 GO:0032039 integrator complex(GO:0032039)
0.1 0.5 GO:0034274 Atg12-Atg5-Atg16 complex(GO:0034274)
0.1 0.7 GO:0005677 chromatin silencing complex(GO:0005677)
0.1 4.0 GO:0005801 cis-Golgi network(GO:0005801)
0.1 1.0 GO:0031209 SCAR complex(GO:0031209)
0.1 0.8 GO:0030014 CCR4-NOT complex(GO:0030014)
0.1 0.2 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.1 3.3 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.1 0.8 GO:0032433 filopodium tip(GO:0032433)
0.1 2.8 GO:0035371 microtubule plus-end(GO:0035371)
0.0 3.2 GO:0048786 presynaptic active zone(GO:0048786)
0.0 1.8 GO:0005721 pericentric heterochromatin(GO:0005721)
0.0 0.5 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 1.3 GO:0071564 npBAF complex(GO:0071564)
0.0 0.5 GO:0061689 tricellular tight junction(GO:0061689)
0.0 0.6 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.0 0.8 GO:0000153 cytoplasmic ubiquitin ligase complex(GO:0000153)
0.0 0.8 GO:0090544 BAF-type complex(GO:0090544)
0.0 0.6 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 5.7 GO:0005604 basement membrane(GO:0005604)
0.0 1.6 GO:0035580 specific granule lumen(GO:0035580)
0.0 0.5 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 0.2 GO:0070695 FHF complex(GO:0070695)
0.0 0.2 GO:0097059 CNTFR-CLCF1 complex(GO:0097059)
0.0 0.2 GO:0036449 microtubule minus-end(GO:0036449)
0.0 0.6 GO:0000124 SAGA complex(GO:0000124)
0.0 1.7 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.5 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.0 1.0 GO:0030057 desmosome(GO:0030057)
0.0 1.0 GO:0005921 gap junction(GO:0005921)
0.0 0.2 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.0 0.1 GO:0031251 PAN complex(GO:0031251)
0.0 1.8 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 0.3 GO:0030991 intraciliary transport particle A(GO:0030991)
0.0 1.4 GO:0016592 mediator complex(GO:0016592)
0.0 1.8 GO:1903293 protein serine/threonine phosphatase complex(GO:0008287) phosphatase complex(GO:1903293)
0.0 0.7 GO:0001891 phagocytic cup(GO:0001891)
0.0 1.1 GO:0071339 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0 2.7 GO:0101002 ficolin-1-rich granule(GO:0101002) ficolin-1-rich granule lumen(GO:1904813)
0.0 0.9 GO:0035861 site of double-strand break(GO:0035861)
0.0 0.5 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 2.8 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
0.0 0.2 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 0.6 GO:0031304 intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305)
0.0 0.3 GO:0032426 stereocilium tip(GO:0032426)
0.0 0.2 GO:0070552 BRISC complex(GO:0070552)
0.0 9.4 GO:0016607 nuclear speck(GO:0016607)
0.0 0.2 GO:0098560 cytoplasmic side of late endosome membrane(GO:0098560)
0.0 1.7 GO:0005758 mitochondrial intermembrane space(GO:0005758) organelle envelope lumen(GO:0031970)
0.0 0.5 GO:0071437 invadopodium(GO:0071437)
0.0 0.6 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.0 2.1 GO:0016605 PML body(GO:0016605)
0.0 0.1 GO:0032021 NELF complex(GO:0032021)
0.0 0.2 GO:0072487 MSL complex(GO:0072487)
0.0 0.4 GO:0030532 small nuclear ribonucleoprotein complex(GO:0030532)
0.0 0.9 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.9 GO:0005844 polysome(GO:0005844)
0.0 2.8 GO:0019897 extrinsic component of plasma membrane(GO:0019897)
0.0 4.1 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 2.0 GO:0005769 early endosome(GO:0005769)
0.0 0.1 GO:0033647 host intracellular organelle(GO:0033647) host intracellular membrane-bounded organelle(GO:0033648)
0.0 0.2 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 1.2 GO:0001669 acrosomal vesicle(GO:0001669)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
5.0 20.0 GO:0016211 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
1.0 3.1 GO:0015130 mevalonate transmembrane transporter activity(GO:0015130)
0.8 20.4 GO:0045499 chemorepellent activity(GO:0045499)
0.8 4.2 GO:0044729 hemi-methylated DNA-binding(GO:0044729)
0.8 2.3 GO:0016768 spermine synthase activity(GO:0016768)
0.6 6.8 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.5 1.4 GO:0034041 sterol-transporting ATPase activity(GO:0034041)
0.4 1.7 GO:0070012 oligopeptidase activity(GO:0070012)
0.4 2.7 GO:0005166 neurotrophin p75 receptor binding(GO:0005166)
0.3 1.3 GO:1990175 EH domain binding(GO:1990175)
0.3 1.0 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
0.3 1.8 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.3 1.1 GO:0008184 purine nucleobase binding(GO:0002060) glycogen phosphorylase activity(GO:0008184)
0.3 1.3 GO:0061676 importin-alpha family protein binding(GO:0061676)
0.2 2.4 GO:0003696 satellite DNA binding(GO:0003696)
0.2 1.9 GO:0050816 phosphothreonine binding(GO:0050816)
0.2 5.2 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.2 1.9 GO:0033857 diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.2 1.4 GO:0019776 Atg8 ligase activity(GO:0019776)
0.2 1.2 GO:0016774 phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.2 2.0 GO:0001849 complement component C1q binding(GO:0001849)
0.2 0.7 GO:0005010 insulin-like growth factor-activated receptor activity(GO:0005010)
0.2 7.4 GO:0005527 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.2 1.5 GO:0048406 nerve growth factor binding(GO:0048406)
0.2 4.7 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.2 0.6 GO:0016649 electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
0.2 0.5 GO:0070506 high-density lipoprotein particle receptor activity(GO:0070506)
0.2 3.1 GO:0008179 adenylate cyclase binding(GO:0008179)
0.2 24.9 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.2 1.5 GO:1904929 coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway(GO:1904929)
0.2 0.5 GO:0070320 inward rectifier potassium channel inhibitor activity(GO:0070320)
0.2 0.8 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.2 0.6 GO:0045131 pre-mRNA branch point binding(GO:0045131)
0.2 0.6 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.2 2.3 GO:0070324 thyroid hormone binding(GO:0070324)
0.2 0.5 GO:0051380 alpha2-adrenergic receptor activity(GO:0004938) norepinephrine binding(GO:0051380)
0.1 1.9 GO:0019870 potassium channel inhibitor activity(GO:0019870)
0.1 0.7 GO:0050815 phosphoserine binding(GO:0050815)
0.1 1.9 GO:0048273 mitogen-activated protein kinase p38 binding(GO:0048273)
0.1 1.0 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.1 0.7 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.1 0.9 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.1 1.0 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.1 0.9 GO:0034046 poly(G) binding(GO:0034046)
0.1 0.8 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.1 0.4 GO:0070984 SET domain binding(GO:0070984)
0.1 0.7 GO:0031749 D2 dopamine receptor binding(GO:0031749)
0.1 1.7 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.1 0.5 GO:0030021 extracellular matrix structural constituent conferring compression resistance(GO:0030021) structural constituent of tooth enamel(GO:0030345)
0.1 2.1 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.1 1.5 GO:0038132 neuregulin binding(GO:0038132)
0.1 1.3 GO:0030274 LIM domain binding(GO:0030274)
0.1 1.0 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.1 0.4 GO:0000403 Y-form DNA binding(GO:0000403)
0.1 2.5 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.1 1.1 GO:0071532 ankyrin repeat binding(GO:0071532)
0.1 0.5 GO:0097677 STAT family protein binding(GO:0097677)
0.1 0.4 GO:0005199 structural constituent of cell wall(GO:0005199)
0.1 0.5 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.1 5.3 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.1 0.5 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.1 1.6 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723)
0.1 0.3 GO:1901375 acetylcholine transmembrane transporter activity(GO:0005277) acetate ester transmembrane transporter activity(GO:1901375)
0.1 0.9 GO:0004305 ethanolamine kinase activity(GO:0004305)
0.1 1.2 GO:0043995 histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.1 0.8 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.1 1.1 GO:0043125 ErbB-3 class receptor binding(GO:0043125)
0.1 0.4 GO:0004572 mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity(GO:0004572)
0.1 0.2 GO:0003826 alpha-ketoacid dehydrogenase activity(GO:0003826) 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity(GO:0003863)
0.1 1.1 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.1 1.7 GO:0005381 iron ion transmembrane transporter activity(GO:0005381)
0.1 1.8 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.1 0.3 GO:0001515 opioid peptide activity(GO:0001515)
0.1 2.6 GO:0070064 proline-rich region binding(GO:0070064)
0.1 2.1 GO:0004707 MAP kinase activity(GO:0004707)
0.1 1.9 GO:0061630 ubiquitin protein ligase activity(GO:0061630) ubiquitin-like protein ligase activity(GO:0061659)
0.1 0.5 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.1 0.9 GO:0015924 mannosyl-oligosaccharide mannosidase activity(GO:0015924)
0.1 0.4 GO:0051022 GDP-dissociation inhibitor binding(GO:0051021) Rho GDP-dissociation inhibitor binding(GO:0051022)
0.1 10.2 GO:0003697 single-stranded DNA binding(GO:0003697)
0.1 0.9 GO:0051430 corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.1 0.7 GO:0022820 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.1 0.4 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.1 1.8 GO:0038191 neuropilin binding(GO:0038191)
0.1 2.9 GO:0000175 3'-5'-exoribonuclease activity(GO:0000175)
0.1 1.8 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.1 1.6 GO:0008242 omega peptidase activity(GO:0008242)
0.1 0.5 GO:0016416 O-palmitoyltransferase activity(GO:0016416)
0.1 1.4 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 0.3 GO:0004924 oncostatin-M receptor activity(GO:0004924)
0.0 0.2 GO:0031708 endothelin B receptor binding(GO:0031708)
0.0 6.3 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 1.5 GO:0004029 aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.0 1.4 GO:0019789 SUMO transferase activity(GO:0019789)
0.0 0.5 GO:0030957 Tat protein binding(GO:0030957)
0.0 6.4 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.0 1.1 GO:0016864 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0 1.2 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 1.8 GO:0001972 retinoic acid binding(GO:0001972)
0.0 1.1 GO:0019208 phosphatase regulator activity(GO:0019208)
0.0 1.6 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.5 GO:0003700 transcription factor activity, sequence-specific DNA binding(GO:0003700)
0.0 2.7 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0 0.3 GO:0004331 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.0 0.2 GO:0017099 very-long-chain-acyl-CoA dehydrogenase activity(GO:0017099)
0.0 0.2 GO:0004850 uridine phosphorylase activity(GO:0004850)
0.0 0.7 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.5 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0 2.2 GO:0030331 estrogen receptor binding(GO:0030331)
0.0 0.2 GO:0047631 ADP-ribose diphosphatase activity(GO:0047631)
0.0 0.8 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.9 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.0 3.0 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.3 GO:0031711 peptidyl-dipeptidase activity(GO:0008241) bradykinin receptor binding(GO:0031711)
0.0 0.1 GO:0042954 lipoprotein transporter activity(GO:0042954)
0.0 1.1 GO:0017025 TBP-class protein binding(GO:0017025)
0.0 1.4 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.9 GO:0070300 phosphatidic acid binding(GO:0070300)
0.0 1.4 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 1.2 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.0 1.2 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.0 0.6 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.0 2.7 GO:0004004 ATP-dependent RNA helicase activity(GO:0004004) RNA-dependent ATPase activity(GO:0008186)
0.0 1.3 GO:0015248 sterol transporter activity(GO:0015248)
0.0 1.9 GO:0016303 1-phosphatidylinositol-3-kinase activity(GO:0016303)
0.0 0.9 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.0 0.8 GO:0098748 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 1.5 GO:0030332 cyclin binding(GO:0030332)
0.0 0.2 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.0 2.6 GO:0004407 histone deacetylase activity(GO:0004407)
0.0 0.5 GO:0051879 Hsp90 protein binding(GO:0051879)
0.0 0.2 GO:0004897 ciliary neurotrophic factor receptor activity(GO:0004897)
0.0 0.6 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 2.6 GO:0003725 double-stranded RNA binding(GO:0003725)
0.0 0.1 GO:0033149 FFAT motif binding(GO:0033149)
0.0 1.6 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 0.1 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
0.0 1.2 GO:0070412 R-SMAD binding(GO:0070412)
0.0 1.0 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.8 GO:0000983 transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
0.0 0.2 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 1.3 GO:0030544 Hsp70 protein binding(GO:0030544)
0.0 1.0 GO:0019903 protein phosphatase binding(GO:0019903)
0.0 0.8 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0 1.9 GO:0000980 RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980)
0.0 0.1 GO:0004104 acetylcholinesterase activity(GO:0003990) cholinesterase activity(GO:0004104)
0.0 0.1 GO:0032184 SUMO polymer binding(GO:0032184)
0.0 2.9 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.8 GO:0001221 transcription cofactor binding(GO:0001221)
0.0 2.6 GO:0047485 protein N-terminus binding(GO:0047485)
0.0 0.1 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0 0.3 GO:0001158 enhancer sequence-specific DNA binding(GO:0001158)
0.0 0.5 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 2.8 GO:0008083 growth factor activity(GO:0008083)
0.0 0.9 GO:0070063 RNA polymerase binding(GO:0070063)
0.0 0.4 GO:0043495 protein anchor(GO:0043495)
0.0 1.7 GO:0051087 chaperone binding(GO:0051087)
0.0 0.8 GO:0035064 methylated histone binding(GO:0035064)
0.0 0.2 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 0.1 GO:0071253 connexin binding(GO:0071253)
0.0 0.7 GO:0030695 GTPase regulator activity(GO:0030695)
0.0 0.2 GO:0019826 oxygen sensor activity(GO:0019826)
0.0 0.1 GO:0004993 G-protein coupled serotonin receptor activity(GO:0004993)
0.0 0.3 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 0.0 GO:0050698 proteoglycan sulfotransferase activity(GO:0050698)
0.0 0.2 GO:0009982 pseudouridine synthase activity(GO:0009982)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.5 PID WNT SIGNALING PATHWAY Wnt signaling network
0.1 1.4 ST JAK STAT PATHWAY Jak-STAT Pathway
0.1 3.4 PID IL5 PATHWAY IL5-mediated signaling events
0.1 2.3 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.1 5.4 PID VEGFR1 PATHWAY VEGFR1 specific signals
0.1 6.4 PID EPHA FWDPATHWAY EPHA forward signaling
0.1 8.1 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.1 5.9 PID NCADHERIN PATHWAY N-cadherin signaling events
0.1 2.2 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.1 5.7 PID PTP1B PATHWAY Signaling events mediated by PTP1B
0.1 21.4 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.1 0.9 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.1 2.7 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.1 4.9 PID SHP2 PATHWAY SHP2 signaling
0.1 2.2 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.1 9.5 PID TELOMERASE PATHWAY Regulation of Telomerase
0.1 1.0 PID ER NONGENOMIC PATHWAY Plasma membrane estrogen receptor signaling
0.1 1.7 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.1 6.4 PID CDC42 PATHWAY CDC42 signaling events
0.0 2.2 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.0 0.5 ST G ALPHA I PATHWAY G alpha i Pathway
0.0 1.7 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 2.3 PID THROMBIN PAR1 PATHWAY PAR1-mediated thrombin signaling events
0.0 2.3 PID ARF6 PATHWAY Arf6 signaling events
0.0 1.6 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 1.6 PID ATM PATHWAY ATM pathway
0.0 2.4 PID PLK1 PATHWAY PLK1 signaling events
0.0 0.4 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.0 1.7 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 8.8 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.8 PID ARF 3PATHWAY Arf1 pathway
0.0 1.0 PID RAC1 PATHWAY RAC1 signaling pathway
0.0 2.1 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 2.2 PID MTOR 4PATHWAY mTOR signaling pathway
0.0 1.5 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 2.7 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 0.8 PID TNF PATHWAY TNF receptor signaling pathway
0.0 0.4 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.0 0.5 PID TCPTP PATHWAY Signaling events mediated by TCPTP
0.0 0.4 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 0.2 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 1.8 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 0.5 PID CONE PATHWAY Visual signal transduction: Cones
0.0 0.9 PID ATF2 PATHWAY ATF-2 transcription factor network
0.0 0.7 PID RAS PATHWAY Regulation of Ras family activation
0.0 2.2 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.0 1.3 PID P73PATHWAY p73 transcription factor network
0.0 0.3 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 0.3 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.0 0.9 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 0.3 PID PS1 PATHWAY Presenilin action in Notch and Wnt signaling
0.0 0.7 PID P75 NTR PATHWAY p75(NTR)-mediated signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 18.9 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.4 7.9 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.3 18.6 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.2 1.5 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.2 5.2 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.2 2.7 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.2 3.6 REACTOME SOS MEDIATED SIGNALLING Genes involved in SOS-mediated signalling
0.1 3.1 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.1 2.6 REACTOME REGULATED PROTEOLYSIS OF P75NTR Genes involved in Regulated proteolysis of p75NTR
0.1 2.0 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.1 1.3 REACTOME ARMS MEDIATED ACTIVATION Genes involved in ARMS-mediated activation
0.1 2.9 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.1 1.0 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.1 0.9 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.1 2.9 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.1 4.4 REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.1 0.5 REACTOME TRANSCRIPTIONAL ACTIVITY OF SMAD2 SMAD3 SMAD4 HETEROTRIMER Genes involved in Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer
0.1 1.2 REACTOME SIGNAL TRANSDUCTION BY L1 Genes involved in Signal transduction by L1
0.1 2.4 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.1 2.2 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.1 2.0 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.1 4.5 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.1 1.4 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.1 1.5 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.1 1.3 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.1 9.2 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.1 1.8 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.1 1.0 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.1 2.0 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.1 0.7 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.0 0.3 REACTOME SIGNALING BY NOTCH3 Genes involved in Signaling by NOTCH3
0.0 1.6 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 1.9 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 3.9 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 1.0 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 1.1 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 0.8 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 0.9 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.9 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 0.7 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 3.1 REACTOME SIGNALING BY NOTCH1 Genes involved in Signaling by NOTCH1
0.0 1.1 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.0 0.3 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0 1.4 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.8 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.0 1.1 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 0.5 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.0 0.5 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.0 0.6 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.9 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0 0.8 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.0 2.1 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.0 0.5 REACTOME ENOS ACTIVATION AND REGULATION Genes involved in eNOS activation and regulation
0.0 0.4 REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS Genes involved in Regulation of Water Balance by Renal Aquaporins
0.0 0.3 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.0 0.4 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 0.3 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 0.3 REACTOME GRB2 EVENTS IN ERBB2 SIGNALING Genes involved in GRB2 events in ERBB2 signaling
0.0 0.5 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 0.5 REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR Genes involved in Prostacyclin signalling through prostacyclin receptor
0.0 0.5 REACTOME CIRCADIAN CLOCK Genes involved in Circadian Clock
0.0 0.7 REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D Genes involved in Metabolism of steroid hormones and vitamins A and D
0.0 0.2 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism