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SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for LHX3

Z-value: 0.79

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Transcription factors associated with LHX3

Gene Symbol Gene ID Gene Info
LHX3
ENSG00000107187.11 LIM homeobox 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
LHX3hg19_v2_chr9_-_139096955_1390969790.135.7e-01Click!

Activity profile of LHX3 motif

Sorted Z-values of LHX3 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr4_+_155484155 4.15 ENST00000509493.1
FGB
fibrinogen beta chain
chr4_+_155484103 4.02 ENST00000302068.4
FGB
fibrinogen beta chain
chr9_-_75567962 3.43 ENST00000297785.3
ENST00000376939.1
ALDH1A1
aldehyde dehydrogenase 1 family, member A1
chr8_-_124741451 3.39 ENST00000520519.1
ANXA13
annexin A13
chr17_-_64225508 2.35 ENST00000205948.6
APOH
apolipoprotein H (beta-2-glycoprotein I)
chr12_+_49740700 1.81 ENST00000549441.2
ENST00000395069.3
DNAJC22
DnaJ (Hsp40) homolog, subfamily C, member 22
chr11_-_559377 1.63 ENST00000486629.1
C11orf35
chromosome 11 open reading frame 35
chr19_-_11457162 1.58 ENST00000590482.1
TMEM205
transmembrane protein 205
chr19_+_50016610 1.58 ENST00000596975.1
FCGRT
Fc fragment of IgG, receptor, transporter, alpha
chr7_+_134671234 1.58 ENST00000436302.2
ENST00000359383.3
ENST00000458078.1
ENST00000435976.2
ENST00000455283.2
AGBL3
ATP/GTP binding protein-like 3
chr19_+_11457175 1.57 ENST00000458408.1
ENST00000586451.1
ENST00000588592.1
CCDC159
coiled-coil domain containing 159
chr19_+_50016411 1.57 ENST00000426395.3
ENST00000600273.1
ENST00000599988.1
FCGRT
Fc fragment of IgG, receptor, transporter, alpha
chr14_-_21566731 1.55 ENST00000360947.3
ZNF219
zinc finger protein 219
chrX_-_106243451 1.37 ENST00000355610.4
ENST00000535534.1
MORC4
MORC family CW-type zinc finger 4
chr20_+_5987890 1.32 ENST00000378868.4
CRLS1
cardiolipin synthase 1
chr19_+_11457232 1.28 ENST00000587531.1
CCDC159
coiled-coil domain containing 159
chr10_+_18549645 1.10 ENST00000396576.2
CACNB2
calcium channel, voltage-dependent, beta 2 subunit
chr9_-_21482312 1.09 ENST00000448696.3
IFNE
interferon, epsilon
chr12_-_52761262 1.09 ENST00000257901.3
KRT85
keratin 85
chr16_+_89334512 1.04 ENST00000602042.1
AC137932.1
AC137932.1
chrX_-_106243294 0.99 ENST00000255495.7
MORC4
MORC family CW-type zinc finger 4
chr16_-_28937027 0.95 ENST00000358201.4
RABEP2
rabaptin, RAB GTPase binding effector protein 2
chr10_+_695888 0.94 ENST00000441152.2
PRR26
proline rich 26
chr17_-_8263538 0.91 ENST00000535173.1
AC135178.1
HCG1985372; Uncharacterized protein; cDNA FLJ37541 fis, clone BRCAN2026340
chr16_+_28565230 0.89 ENST00000317058.3
CCDC101
coiled-coil domain containing 101
chr18_+_61616510 0.87 ENST00000408945.3
HMSD
histocompatibility (minor) serpin domain containing
chr9_-_100000957 0.86 ENST00000366109.2
ENST00000607322.1
RP11-498P14.5
RP11-498P14.5
chr6_-_47445214 0.84 ENST00000604014.1
RP11-385F7.1
RP11-385F7.1
chrX_-_19504642 0.83 ENST00000469203.2
MAP3K15
mitogen-activated protein kinase kinase kinase 15
chrX_-_110655306 0.83 ENST00000371993.2
DCX
doublecortin
chr2_+_234826016 0.78 ENST00000324695.4
ENST00000433712.2
TRPM8
transient receptor potential cation channel, subfamily M, member 8
chr1_+_66820058 0.78 ENST00000480109.2
PDE4B
phosphodiesterase 4B, cAMP-specific
chr10_+_696000 0.77 ENST00000381489.5
PRR26
proline rich 26
chr17_-_4938712 0.77 ENST00000254853.5
ENST00000424747.1
SLC52A1
solute carrier family 52 (riboflavin transporter), member 1
chr17_+_68071389 0.75 ENST00000283936.1
ENST00000392671.1
KCNJ16
potassium inwardly-rectifying channel, subfamily J, member 16
chr19_-_49149553 0.74 ENST00000084798.4
CA11
carbonic anhydrase XI
chr8_-_25281747 0.73 ENST00000421054.2
GNRH1
gonadotropin-releasing hormone 1 (luteinizing-releasing hormone)
chr17_-_72772462 0.71 ENST00000582870.1
ENST00000581136.1
ENST00000357814.3
ENST00000579218.1
ENST00000583476.1
ENST00000580301.1
ENST00000583757.1
ENST00000582524.1
NAT9
N-acetyltransferase 9 (GCN5-related, putative)
chr14_-_21567009 0.71 ENST00000556174.1
ENST00000554478.1
ENST00000553980.1
ENST00000421093.2
ZNF219
zinc finger protein 219
chr2_-_228582709 0.69 ENST00000541617.1
ENST00000409456.2
ENST00000409287.1
ENST00000258403.3
SLC19A3
solute carrier family 19 (thiamine transporter), member 3
chr1_+_244214577 0.68 ENST00000358704.4
ZBTB18
zinc finger and BTB domain containing 18
chr1_-_45988542 0.64 ENST00000424390.1
PRDX1
peroxiredoxin 1
chr19_+_48949030 0.63 ENST00000253237.5
GRWD1
glutamate-rich WD repeat containing 1
chr14_-_54425475 0.62 ENST00000559642.1
BMP4
bone morphogenetic protein 4
chr9_-_128246769 0.61 ENST00000444226.1
MAPKAP1
mitogen-activated protein kinase associated protein 1
chr7_-_87342564 0.61 ENST00000265724.3
ENST00000416177.1
ABCB1
ATP-binding cassette, sub-family B (MDR/TAP), member 1
chr12_-_85430024 0.59 ENST00000547836.1
ENST00000532498.2
TSPAN19
tetraspanin 19
chr17_+_68071458 0.58 ENST00000589377.1
KCNJ16
potassium inwardly-rectifying channel, subfamily J, member 16
chr6_-_49712147 0.55 ENST00000433368.2
ENST00000354620.4
CRISP3
cysteine-rich secretory protein 3
chr3_-_191000172 0.55 ENST00000427544.2
UTS2B
urotensin 2B
chr17_-_27418537 0.52 ENST00000408971.2
TIAF1
TGFB1-induced anti-apoptotic factor 1
chr14_+_29241910 0.52 ENST00000399387.4
ENST00000552957.1
ENST00000548213.1
C14orf23
chromosome 14 open reading frame 23
chr4_-_120243545 0.51 ENST00000274024.3
FABP2
fatty acid binding protein 2, intestinal
chr10_-_128359074 0.51 ENST00000544758.1
C10orf90
chromosome 10 open reading frame 90
chr2_+_135596180 0.50 ENST00000283054.4
ENST00000392928.1
ACMSD
aminocarboxymuconate semialdehyde decarboxylase
chr12_-_86650045 0.49 ENST00000604798.1
MGAT4C
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme C (putative)
chr1_-_24126023 0.48 ENST00000429356.1
GALE
UDP-galactose-4-epimerase
chr12_+_8309630 0.47 ENST00000396570.3
ZNF705A
zinc finger protein 705A
chr4_-_41884620 0.46 ENST00000504870.1
LINC00682
long intergenic non-protein coding RNA 682
chrX_-_13835147 0.46 ENST00000493677.1
ENST00000355135.2
GPM6B
glycoprotein M6B
chr5_+_140529630 0.45 ENST00000543635.1
PCDHB6
protocadherin beta 6
chr3_+_148415571 0.44 ENST00000497524.1
ENST00000349243.3
ENST00000542281.1
ENST00000418473.2
ENST00000404754.2
AGTR1
angiotensin II receptor, type 1
chr22_+_17956618 0.42 ENST00000262608.8
CECR2
cat eye syndrome chromosome region, candidate 2
chr8_-_110986918 0.40 ENST00000297404.1
KCNV1
potassium channel, subfamily V, member 1
chr5_-_59783882 0.40 ENST00000505507.2
ENST00000502484.2
PDE4D
phosphodiesterase 4D, cAMP-specific
chr6_+_123317116 0.40 ENST00000275162.5
CLVS2
clavesin 2
chr1_-_24126051 0.39 ENST00000445705.1
GALE
UDP-galactose-4-epimerase
chr1_+_168250194 0.39 ENST00000367821.3
TBX19
T-box 19
chr4_-_103940791 0.39 ENST00000510559.1
ENST00000394789.3
ENST00000296422.7
SLC9B1
solute carrier family 9, subfamily B (NHA1, cation proton antiporter 1), member 1
chrM_+_10053 0.39 ENST00000361227.2
MT-ND3
mitochondrially encoded NADH dehydrogenase 3
chr8_+_119294456 0.38 ENST00000366457.2
AC023590.1
Uncharacterized protein
chr2_-_166930131 0.36 ENST00000303395.4
ENST00000409050.1
ENST00000423058.2
ENST00000375405.3
SCN1A
sodium channel, voltage-gated, type I, alpha subunit
chr2_-_99871570 0.36 ENST00000333017.2
ENST00000409679.1
ENST00000423306.1
LYG2
lysozyme G-like 2
chr4_+_113568207 0.36 ENST00000511529.1
LARP7
La ribonucleoprotein domain family, member 7
chr8_-_66750978 0.35 ENST00000523253.1
PDE7A
phosphodiesterase 7A
chr15_-_81195510 0.35 ENST00000561295.1
RP11-351M8.1
Uncharacterized protein
chr6_-_49712123 0.35 ENST00000263045.4
CRISP3
cysteine-rich secretory protein 3
chr4_-_23891693 0.33 ENST00000264867.2
PPARGC1A
peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
chr1_-_150208291 0.33 ENST00000533654.1
ANP32E
acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
chr11_+_327171 0.33 ENST00000534483.1
ENST00000524824.1
ENST00000531076.1
RP11-326C3.12
RP11-326C3.12
chr8_+_92261516 0.33 ENST00000276609.3
ENST00000309536.2
SLC26A7
solute carrier family 26 (anion exchanger), member 7
chr2_+_135596106 0.33 ENST00000356140.5
ACMSD
aminocarboxymuconate semialdehyde decarboxylase
chr11_-_74800799 0.32 ENST00000305159.3
OR2AT4
olfactory receptor, family 2, subfamily AT, member 4
chrX_+_108779004 0.32 ENST00000218004.1
NXT2
nuclear transport factor 2-like export factor 2
chr14_-_45252031 0.32 ENST00000556405.1
RP11-398E10.1
RP11-398E10.1
chr3_-_20053741 0.32 ENST00000389050.4
PP2D1
protein phosphatase 2C-like domain containing 1
chrX_-_55057403 0.32 ENST00000396198.3
ENST00000335854.4
ENST00000455688.1
ENST00000330807.5
ALAS2
aminolevulinate, delta-, synthase 2
chr5_+_140557371 0.31 ENST00000239444.2
PCDHB8
protocadherin beta 8
chr4_-_68829226 0.31 ENST00000396188.2
TMPRSS11A
transmembrane protease, serine 11A
chr12_-_42631529 0.31 ENST00000548917.1
YAF2
YY1 associated factor 2
chr1_+_15668240 0.31 ENST00000444385.1
FHAD1
forkhead-associated (FHA) phosphopeptide binding domain 1
chr4_-_68829144 0.31 ENST00000508048.1
TMPRSS11A
transmembrane protease, serine 11A
chr12_-_10282836 0.30 ENST00000304084.8
ENST00000353231.5
ENST00000525605.1
CLEC7A
C-type lectin domain family 7, member A
chr2_-_99279928 0.29 ENST00000414521.2
MGAT4A
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A
chr18_+_72201829 0.28 ENST00000582365.1
CNDP1
carnosine dipeptidase 1 (metallopeptidase M20 family)
chr17_-_72772425 0.28 ENST00000578822.1
NAT9
N-acetyltransferase 9 (GCN5-related, putative)
chr6_-_49712091 0.28 ENST00000371159.4
CRISP3
cysteine-rich secretory protein 3
chr7_+_39017504 0.28 ENST00000403058.1
POU6F2
POU class 6 homeobox 2
chr12_-_11287243 0.28 ENST00000539585.1
TAS2R30
taste receptor, type 2, member 30
chrX_+_9431324 0.27 ENST00000407597.2
ENST00000424279.1
ENST00000536365.1
ENST00000441088.1
ENST00000380961.1
ENST00000415293.1
TBL1X
transducin (beta)-like 1X-linked
chr18_+_28956740 0.26 ENST00000308128.4
ENST00000359747.4
DSG4
desmoglein 4
chr5_+_59783941 0.25 ENST00000506884.1
ENST00000504876.2
PART1
prostate androgen-regulated transcript 1 (non-protein coding)
chr17_-_28661065 0.25 ENST00000328886.4
ENST00000538566.2
TMIGD1
transmembrane and immunoglobulin domain containing 1
chr7_-_4901625 0.25 ENST00000404991.1
PAPOLB
poly(A) polymerase beta (testis specific)
chr6_+_153019069 0.25 ENST00000532295.1
MYCT1
myc target 1
chr6_-_49712072 0.24 ENST00000423399.2
CRISP3
cysteine-rich secretory protein 3
chr15_+_48483736 0.24 ENST00000417307.2
ENST00000559641.1
CTXN2
SLC12A1
cortexin 2
solute carrier family 12 (sodium/potassium/chloride transporter), member 1
chr1_-_92952433 0.24 ENST00000294702.5
GFI1
growth factor independent 1 transcription repressor
chr14_+_88852059 0.24 ENST00000045347.7
SPATA7
spermatogenesis associated 7
chr3_-_167191814 0.24 ENST00000466903.1
ENST00000264677.4
SERPINI2
serpin peptidase inhibitor, clade I (pancpin), member 2
chr13_+_24144796 0.23 ENST00000403372.2
TNFRSF19
tumor necrosis factor receptor superfamily, member 19
chr4_+_158142750 0.23 ENST00000505888.1
ENST00000449365.1
GRIA2
glutamate receptor, ionotropic, AMPA 2
chr15_+_86686953 0.23 ENST00000421325.2
AGBL1
ATP/GTP binding protein-like 1
chr7_-_22862406 0.22 ENST00000372879.4
TOMM7
translocase of outer mitochondrial membrane 7 homolog (yeast)
chr3_-_47517302 0.22 ENST00000441517.2
ENST00000545718.1
SCAP
SREBF chaperone
chr14_+_21566980 0.22 ENST00000418511.2
ENST00000554329.2
TMEM253
transmembrane protein 253
chr16_+_15489603 0.22 ENST00000568766.1
ENST00000287594.7
RP11-1021N1.1
MPV17L
Uncharacterized protein
MPV17 mitochondrial membrane protein-like
chr10_-_90611566 0.22 ENST00000371930.4
ANKRD22
ankyrin repeat domain 22
chr2_-_231860596 0.22 ENST00000441063.1
ENST00000434094.1
ENST00000418330.1
ENST00000457803.1
ENST00000414876.1
ENST00000446741.1
ENST00000426904.1
AC105344.2
SPATA3 antisense RNA 1 (head to head)
chr12_+_96196875 0.22 ENST00000553095.1
RP11-536G4.1
Uncharacterized protein
chr6_+_153019023 0.21 ENST00000367245.5
ENST00000529453.1
MYCT1
myc target 1
chr8_+_91233750 0.21 ENST00000523406.1
LINC00534
long intergenic non-protein coding RNA 534
chr4_-_23891658 0.20 ENST00000507380.1
PPARGC1A
peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
chr16_+_15489629 0.20 ENST00000396385.3
MPV17L
MPV17 mitochondrial membrane protein-like
chr17_-_71223839 0.20 ENST00000579872.1
ENST00000580032.1
FAM104A
family with sequence similarity 104, member A
chr3_+_2933893 0.19 ENST00000397459.2
CNTN4
contactin 4
chr20_-_656823 0.19 ENST00000246104.6
SCRT2
scratch family zinc finger 2
chr6_+_72926145 0.19 ENST00000425662.2
ENST00000453976.2
RIMS1
regulating synaptic membrane exocytosis 1
chr2_+_47454054 0.19 ENST00000426892.1
AC106869.2
AC106869.2
chr4_+_158493642 0.19 ENST00000507108.1
ENST00000455598.1
ENST00000509450.1
RP11-364P22.1
RP11-364P22.1
chrX_-_52827141 0.18 ENST00000375511.3
SPANXN5
SPANX family, member N5
chr15_+_75970672 0.18 ENST00000435356.1
AC105020.1
Uncharacterized protein; cDNA FLJ12988 fis, clone NT2RP3000080
chr12_-_78934441 0.18 ENST00000546865.1
ENST00000547089.1
RP11-171L9.1
RP11-171L9.1
chr18_+_6774000 0.18 ENST00000532723.1
ARHGAP28
Rho GTPase activating protein 28
chr3_+_151591422 0.18 ENST00000362032.5
SUCNR1
succinate receptor 1
chr16_+_72459838 0.18 ENST00000564508.1
AC004158.3
AC004158.3
chr12_-_10282742 0.17 ENST00000298523.5
ENST00000396484.2
ENST00000310002.4
CLEC7A
C-type lectin domain family 7, member A
chr1_-_160549235 0.17 ENST00000368054.3
ENST00000368048.3
ENST00000311224.4
ENST00000368051.3
ENST00000534968.1
CD84
CD84 molecule
chr1_-_231005310 0.17 ENST00000470540.1
C1orf198
chromosome 1 open reading frame 198
chr3_+_69812877 0.17 ENST00000457080.1
ENST00000328528.6
MITF
microphthalmia-associated transcription factor
chr19_-_51920952 0.16 ENST00000356298.5
ENST00000339313.5
ENST00000529627.1
ENST00000439889.2
ENST00000353836.5
ENST00000432469.2
SIGLEC10
sialic acid binding Ig-like lectin 10
chr1_+_197237352 0.16 ENST00000538660.1
ENST00000367400.3
ENST00000367399.2
CRB1
crumbs homolog 1 (Drosophila)
chr19_+_9296279 0.16 ENST00000344248.2
OR7D2
olfactory receptor, family 7, subfamily D, member 2
chr3_+_46919235 0.16 ENST00000449590.1
PTH1R
parathyroid hormone 1 receptor
chr4_+_158141843 0.15 ENST00000509417.1
ENST00000296526.7
GRIA2
glutamate receptor, ionotropic, AMPA 2
chr18_-_53303123 0.15 ENST00000569357.1
ENST00000565124.1
ENST00000398339.1
TCF4
transcription factor 4
chr1_+_109265033 0.15 ENST00000445274.1
FNDC7
fibronectin type III domain containing 7
chr12_-_86650077 0.15 ENST00000552808.2
ENST00000547225.1
MGAT4C
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme C (putative)
chr1_-_160924589 0.14 ENST00000368029.3
ITLN2
intelectin 2
chr2_-_145278475 0.14 ENST00000558170.2
ZEB2
zinc finger E-box binding homeobox 2
chr6_-_159466136 0.13 ENST00000367066.3
ENST00000326965.6
TAGAP
T-cell activation RhoGTPase activating protein
chr14_+_20215587 0.13 ENST00000331723.1
OR4Q3
olfactory receptor, family 4, subfamily Q, member 3
chr4_+_158141899 0.13 ENST00000264426.9
ENST00000506284.1
GRIA2
glutamate receptor, ionotropic, AMPA 2
chrX_-_39186610 0.13 ENST00000429281.1
ENST00000448597.1
RP11-265P11.2
RP11-265P11.2
chr5_-_173217931 0.13 ENST00000522731.1
CTB-43E15.4
CTB-43E15.4
chr16_-_28634874 0.12 ENST00000395609.1
ENST00000350842.4
SULT1A1
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
chr11_-_63376013 0.12 ENST00000540943.1
PLA2G16
phospholipase A2, group XVI
chr9_+_125132803 0.11 ENST00000540753.1
PTGS1
prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
chr1_-_48866517 0.11 ENST00000371841.1
SPATA6
spermatogenesis associated 6
chr18_+_72201664 0.11 ENST00000358821.3
CNDP1
carnosine dipeptidase 1 (metallopeptidase M20 family)
chr1_-_57285038 0.11 ENST00000343433.6
C1orf168
chromosome 1 open reading frame 168
chr2_+_218994002 0.11 ENST00000428565.1
CXCR2
chemokine (C-X-C motif) receptor 2
chr7_+_97361388 0.11 ENST00000350485.4
ENST00000346867.4
TAC1
tachykinin, precursor 1
chr3_+_68055366 0.10 ENST00000496687.1
FAM19A1
family with sequence similarity 19 (chemokine (C-C motif)-like), member A1
chr13_+_53602894 0.10 ENST00000219022.2
OLFM4
olfactomedin 4
chr21_-_39705286 0.09 ENST00000414189.1
AP001422.3
AP001422.3
chrX_+_107288197 0.08 ENST00000415430.3
VSIG1
V-set and immunoglobulin domain containing 1
chr3_-_145940126 0.08 ENST00000498625.1
PLSCR4
phospholipid scramblase 4
chr5_-_88119580 0.08 ENST00000539796.1
MEF2C
myocyte enhancer factor 2C
chr8_-_104153559 0.08 ENST00000436771.1
C8orf56
chromosome 8 open reading frame 56
chr6_-_2634820 0.08 ENST00000296847.3
C6orf195
chromosome 6 open reading frame 195
chr18_+_616711 0.07 ENST00000579494.1
CLUL1
clusterin-like 1 (retinal)
chr9_+_35042205 0.07 ENST00000312292.5
ENST00000378745.3
C9orf131
chromosome 9 open reading frame 131
chr9_+_125133467 0.07 ENST00000426608.1
PTGS1
prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
chr1_-_150208320 0.06 ENST00000534220.1
ANP32E
acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
chr6_+_83072923 0.06 ENST00000535040.1
TPBG
trophoblast glycoprotein
chr17_-_38956205 0.06 ENST00000306658.7
KRT28
keratin 28
chr9_-_215744 0.06 ENST00000382387.2
C9orf66
chromosome 9 open reading frame 66
chr5_-_145252531 0.05 ENST00000377976.1
GRXCR2
glutaredoxin, cysteine rich 2
chr12_+_59989918 0.05 ENST00000547379.1
ENST00000549465.1
SLC16A7
solute carrier family 16 (monocarboxylate transporter), member 7
chrX_+_107288239 0.05 ENST00000217957.5
VSIG1
V-set and immunoglobulin domain containing 1
chr6_-_9933500 0.05 ENST00000492169.1
OFCC1
orofacial cleft 1 candidate 1
chr12_-_7656357 0.04 ENST00000396620.3
ENST00000432237.2
ENST00000359156.4
CD163
CD163 molecule
chr7_-_115799942 0.03 ENST00000484212.1
TFEC
transcription factor EC
chr14_-_106668095 0.03 ENST00000390606.2
IGHV3-20
immunoglobulin heavy variable 3-20
chr3_+_121902511 0.03 ENST00000490131.1
CASR
calcium-sensing receptor
chr7_-_122840015 0.03 ENST00000194130.2
SLC13A1
solute carrier family 13 (sodium/sulfate symporter), member 1
chr6_+_26104104 0.02 ENST00000377803.2
HIST1H4C
histone cluster 1, H4c
chr18_+_616672 0.02 ENST00000338387.7
CLUL1
clusterin-like 1 (retinal)
chr6_+_114178512 0.02 ENST00000368635.4
MARCKS
myristoylated alanine-rich protein kinase C substrate
chr2_-_8715616 0.02 ENST00000418358.1
AC011747.3
AC011747.3
chr7_-_36764142 0.01 ENST00000258749.5
ENST00000535891.1
AOAH
acyloxyacyl hydrolase (neutrophil)
chr17_-_39623681 0.01 ENST00000225899.3
KRT32
keratin 32
chr8_-_104153703 0.01 ENST00000521246.1
C8orf56
chromosome 8 open reading frame 56
chr19_+_14693888 0.00 ENST00000547437.1
ENST00000397439.2
ENST00000417570.1
CLEC17A
C-type lectin domain family 17, member A
chr16_-_1538765 0.00 ENST00000447419.2
ENST00000440447.2
PTX4
pentraxin 4, long
chr2_-_14541060 0.00 ENST00000418420.1
ENST00000417751.1
LINC00276
long intergenic non-protein coding RNA 276

Network of associatons between targets according to the STRING database.

First level regulatory network of LHX3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 3.1 GO:0002416 IgG immunoglobulin transcytosis in epithelial cells mediated by FcRn immunoglobulin receptor(GO:0002416)
0.6 8.2 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.6 3.4 GO:0006001 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
0.2 1.8 GO:0035610 protein side chain deglutamylation(GO:0035610)
0.2 2.3 GO:0034392 negative regulation of smooth muscle cell apoptotic process(GO:0034392)
0.2 0.7 GO:1990637 response to prolactin(GO:1990637)
0.2 0.5 GO:1904640 positive regulation of mitochondrial DNA metabolic process(GO:1901860) response to methionine(GO:1904640)
0.2 0.8 GO:0032218 riboflavin transport(GO:0032218)
0.1 1.3 GO:1904386 response to thyroxine(GO:0097068) response to L-phenylalanine derivative(GO:1904386)
0.1 0.7 GO:0071934 thiamine transmembrane transport(GO:0071934)
0.1 1.1 GO:0098912 membrane depolarization during atrial cardiac muscle cell action potential(GO:0098912) positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.1 0.6 GO:2000007 apoptotic process involved in endocardial cushion morphogenesis(GO:0003277) intermediate mesoderm morphogenesis(GO:0048390) intermediate mesoderm formation(GO:0048391) intermediate mesodermal cell differentiation(GO:0048392) regulation of cardiac muscle fiber development(GO:0055018) positive regulation of cardiac muscle fiber development(GO:0055020) bud dilation involved in lung branching(GO:0060503) BMP signaling pathway involved in ureter morphogenesis(GO:0061149) renal system segmentation(GO:0061150) BMP signaling pathway involved in renal system segmentation(GO:0061151) pulmonary artery endothelial tube morphogenesis(GO:0061155) regulation of transcription from RNA polymerase II promoter involved in mesonephros development(GO:0061216) BMP signaling pathway involved in nephric duct formation(GO:0071893) negative regulation of branch elongation involved in ureteric bud branching(GO:0072096) negative regulation of branch elongation involved in ureteric bud branching by BMP signaling pathway(GO:0072097) anterior/posterior pattern specification involved in ureteric bud development(GO:0072099) specification of ureteric bud anterior/posterior symmetry(GO:0072100) specification of ureteric bud anterior/posterior symmetry by BMP signaling pathway(GO:0072101) ureter epithelial cell differentiation(GO:0072192) negative regulation of mesenchymal cell proliferation involved in ureter development(GO:0072200) positive regulation of cell proliferation involved in outflow tract morphogenesis(GO:1901964) cardiac jelly development(GO:1905072) regulation of metanephric S-shaped body morphogenesis(GO:2000004) negative regulation of metanephric S-shaped body morphogenesis(GO:2000005) regulation of metanephric comma-shaped body morphogenesis(GO:2000006) negative regulation of metanephric comma-shaped body morphogenesis(GO:2000007)
0.1 0.8 GO:0019805 quinolinate biosynthetic process(GO:0019805)
0.1 0.8 GO:0050955 thermoception(GO:0050955)
0.1 0.4 GO:0086097 phospholipase C-activating angiotensin-activated signaling pathway(GO:0086097)
0.1 0.6 GO:0030950 establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.1 0.4 GO:0010730 negative regulation of hydrogen peroxide biosynthetic process(GO:0010730)
0.1 0.2 GO:0070105 positive regulation of interleukin-6-mediated signaling pathway(GO:0070105)
0.1 1.2 GO:1901898 negative regulation of relaxation of muscle(GO:1901078) negative regulation of relaxation of cardiac muscle(GO:1901898)
0.1 0.6 GO:1901529 positive regulation of anion channel activity(GO:1901529)
0.1 1.1 GO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.1 0.3 GO:0007402 ganglion mother cell fate determination(GO:0007402)
0.0 0.9 GO:0019388 galactose catabolic process(GO:0019388)
0.0 0.4 GO:0009253 peptidoglycan metabolic process(GO:0000270) peptidoglycan catabolic process(GO:0009253)
0.0 0.2 GO:1904425 negative regulation of GTP binding(GO:1904425)
0.0 0.5 GO:0051612 negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.0 0.1 GO:2000854 positive regulation of corticosterone secretion(GO:2000854)
0.0 0.2 GO:0032661 regulation of interleukin-18 production(GO:0032661)
0.0 0.2 GO:0045541 negative regulation of cholesterol biosynthetic process(GO:0045541) positive regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045716) negative regulation of cholesterol metabolic process(GO:0090206)
0.0 0.4 GO:0050966 detection of mechanical stimulus involved in sensory perception of pain(GO:0050966)
0.0 0.5 GO:0009756 carbohydrate mediated signaling(GO:0009756)
0.0 0.3 GO:0006782 protoporphyrinogen IX biosynthetic process(GO:0006782)
0.0 1.3 GO:0010107 potassium ion import(GO:0010107)
0.0 0.2 GO:0045040 protein import into mitochondrial outer membrane(GO:0045040)
0.0 0.6 GO:0042744 hydrogen peroxide catabolic process(GO:0042744)
0.0 0.2 GO:1903546 protein localization to photoreceptor outer segment(GO:1903546)
0.0 0.1 GO:0038112 interleukin-8-mediated signaling pathway(GO:0038112)
0.0 0.3 GO:0019532 oxalate transport(GO:0019532)
0.0 0.1 GO:1902748 positive regulation of lens fiber cell differentiation(GO:1902748)
0.0 0.4 GO:0006309 apoptotic DNA fragmentation(GO:0006309)
0.0 0.1 GO:0046485 ether lipid metabolic process(GO:0046485)
0.0 0.7 GO:0007519 skeletal muscle tissue development(GO:0007519)
0.0 0.3 GO:0006337 nucleosome disassembly(GO:0006337)
0.0 0.5 GO:0019433 triglyceride catabolic process(GO:0019433)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 8.2 GO:0005577 fibrinogen complex(GO:0005577)
0.1 2.3 GO:0031089 platelet dense granule lumen(GO:0031089)
0.1 0.5 GO:0098843 postsynaptic endocytic zone(GO:0098843)
0.1 0.7 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.1 1.1 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 0.1 GO:0097224 sperm connecting piece(GO:0097224)
0.0 0.4 GO:0031010 ISWI-type complex(GO:0031010)
0.0 0.6 GO:0031932 TORC2 complex(GO:0031932)
0.0 0.2 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 0.8 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 0.4 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.5 GO:0097440 apical dendrite(GO:0097440)
0.0 1.5 GO:1904724 tertiary granule lumen(GO:1904724)
0.0 1.1 GO:0045095 keratin filament(GO:0045095)
0.0 1.7 GO:0008076 voltage-gated potassium channel complex(GO:0008076)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 3.1 GO:0019770 IgG receptor activity(GO:0019770)
0.5 2.3 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.4 1.3 GO:0008808 cardiolipin synthase activity(GO:0008808) phosphatidyltransferase activity(GO:0030572) CDP-diacylglycerol-phosphatidylglycerol phosphatidyltransferase activity(GO:0043337)
0.4 3.4 GO:0018479 benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.2 0.9 GO:0003978 UDP-N-acetylglucosamine 4-epimerase activity(GO:0003974) UDP-glucose 4-epimerase activity(GO:0003978)
0.2 2.3 GO:0004969 histamine receptor activity(GO:0004969)
0.2 0.7 GO:0015403 thiamine uptake transmembrane transporter activity(GO:0015403)
0.2 0.8 GO:0032217 riboflavin transporter activity(GO:0032217)
0.1 0.4 GO:0001596 angiotensin type I receptor activity(GO:0001596)
0.1 1.1 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.1 1.1 GO:0005132 type I interferon receptor binding(GO:0005132)
0.1 0.9 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.1 0.3 GO:0003870 5-aminolevulinate synthase activity(GO:0003870) N-succinyltransferase activity(GO:0016749)
0.1 0.6 GO:0090554 phosphatidylcholine-translocating ATPase activity(GO:0090554)
0.1 0.2 GO:0008511 sodium:potassium:chloride symporter activity(GO:0008511)
0.1 0.6 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.1 1.3 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 8.2 GO:0051087 chaperone binding(GO:0051087)
0.0 1.8 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.6 GO:0070700 BMP receptor binding(GO:0070700)
0.0 0.7 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 1.5 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.5 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.0 0.2 GO:0004991 parathyroid hormone receptor activity(GO:0004991)
0.0 0.4 GO:0003796 lysozyme activity(GO:0003796)
0.0 0.5 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 3.4 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 1.0 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 0.1 GO:0052740 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
0.0 0.4 GO:0015385 sodium:proton antiporter activity(GO:0015385)
0.0 0.2 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.0 0.3 GO:0033038 bitter taste receptor activity(GO:0033038)
0.0 0.1 GO:0004918 interleukin-8 receptor activity(GO:0004918)
0.0 0.3 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 0.1 GO:0047894 flavonol 3-sulfotransferase activity(GO:0047894) steroid sulfotransferase activity(GO:0050294)
0.0 0.2 GO:0015266 protein channel activity(GO:0015266)
0.0 0.3 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.0 GO:0008271 secondary active sulfate transmembrane transporter activity(GO:0008271)
0.0 0.1 GO:0005477 pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.0 0.5 GO:0008329 signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187)
0.0 0.8 GO:0016831 carboxy-lyase activity(GO:0016831)
0.0 0.4 GO:0016805 dipeptidase activity(GO:0016805)
0.0 0.4 GO:1905030 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0 1.3 GO:0005179 hormone activity(GO:0005179)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 8.2 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 0.8 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 3.5 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.5 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 0.5 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 8.2 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.2 3.4 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.1 0.7 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.1 1.3 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.0 1.1 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.0 0.6 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.0 0.8 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 1.3 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 0.1 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.0 0.8 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.5 REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.0 0.4 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.6 REACTOME PIP3 ACTIVATES AKT SIGNALING Genes involved in PIP3 activates AKT signaling