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SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for LHX6

Z-value: 0.81

Motif logo

Transcription factors associated with LHX6

Gene Symbol Gene ID Gene Info
ENSG00000106852.11 LIM homeobox 6

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
LHX6hg19_v2_chr9_-_124976185_124976212-0.521.9e-02Click!

Activity profile of LHX6 motif

Sorted Z-values of LHX6 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr11_+_5710919 2.85 ENST00000379965.3
ENST00000425490.1
tripartite motif containing 22
chr18_+_61143994 2.24 ENST00000382771.4
serpin peptidase inhibitor, clade B (ovalbumin), member 5
chr3_-_151034734 2.23 ENST00000260843.4
G protein-coupled receptor 87
chr1_+_145438469 2.19 ENST00000369317.4
thioredoxin interacting protein
chr19_-_54663473 1.94 ENST00000222224.3
leukocyte receptor cluster (LRC) member 1
chr5_-_112630598 1.74 ENST00000302475.4
mutated in colorectal cancers
chr17_-_7167279 1.69 ENST00000571932.2
claudin 7
chr7_-_121784285 1.39 ENST00000417368.2
aminoadipate-semialdehyde synthase
chr7_+_37723336 1.27 ENST00000450180.1
G protein-coupled receptor 141
chr11_-_102668879 1.26 ENST00000315274.6
matrix metallopeptidase 1 (interstitial collagenase)
chr6_-_167040693 1.24 ENST00000366863.2
ribosomal protein S6 kinase, 90kDa, polypeptide 2
chr11_+_117947782 1.18 ENST00000522307.1
ENST00000523251.1
ENST00000437212.3
ENST00000522824.1
ENST00000522151.1
transmembrane protease, serine 4
chr6_-_167040731 1.11 ENST00000265678.4
ribosomal protein S6 kinase, 90kDa, polypeptide 2
chr12_-_56753858 1.11 ENST00000314128.4
ENST00000557235.1
ENST00000418572.2
signal transducer and activator of transcription 2, 113kDa
chr17_-_1532106 1.09 ENST00000301335.5
ENST00000382147.4
solute carrier family 43 (amino acid system L transporter), member 2
chr19_-_53400813 1.07 ENST00000595635.1
ENST00000594741.1
ENST00000597111.1
ENST00000593618.1
ENST00000597909.1
zinc finger protein 320
chr11_-_102651343 0.96 ENST00000279441.4
ENST00000539681.1
matrix metallopeptidase 10 (stromelysin 2)
chr6_+_29691198 0.93 ENST00000440587.2
ENST00000434407.2
major histocompatibility complex, class I, F
chr10_-_28571015 0.90 ENST00000375719.3
ENST00000375732.1
membrane protein, palmitoylated 7 (MAGUK p55 subfamily member 7)
chr12_-_91546926 0.90 ENST00000550758.1
decorin
chr6_-_32095968 0.89 ENST00000375203.3
ENST00000375201.4
activating transcription factor 6 beta
chr19_-_12833164 0.88 ENST00000356861.5
transportin 2
chr2_+_220143989 0.86 ENST00000336576.5
DnaJ (Hsp40) homolog, subfamily B, member 2
chr16_+_55512742 0.80 ENST00000568715.1
ENST00000219070.4
matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
chr17_+_30089454 0.79 ENST00000577970.1
RP11-805L22.3
chr22_-_42017021 0.79 ENST00000263256.6
desumoylating isopeptidase 1
chr13_-_86373536 0.79 ENST00000400286.2
SLIT and NTRK-like family, member 6
chr3_-_42003613 0.76 ENST00000414606.1
unc-51 like kinase 4
chr1_+_44115814 0.75 ENST00000372396.3
lysine (K)-specific demethylase 4A
chr11_+_117947724 0.74 ENST00000534111.1
transmembrane protease, serine 4
chr19_-_14606900 0.74 ENST00000393029.3
ENST00000393028.1
ENST00000393033.4
ENST00000345425.2
ENST00000586027.1
ENST00000591349.1
ENST00000587210.1
GIPC PDZ domain containing family, member 1
chr6_+_30457244 0.73 ENST00000376630.4
major histocompatibility complex, class I, E
chrX_-_24690771 0.73 ENST00000379145.1
phosphate cytidylyltransferase 1, choline, beta
chr21_-_43916433 0.72 ENST00000291536.3
radial spoke head 1 homolog (Chlamydomonas)
chr17_+_41476327 0.71 ENST00000320033.4
ADP-ribosylation factor-like 4D
chr3_-_160823040 0.70 ENST00000484127.1
ENST00000492353.1
ENST00000473142.1
ENST00000468268.1
ENST00000460353.1
ENST00000320474.4
ENST00000392781.2
beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group)
chr13_+_37006421 0.66 ENST00000255465.4
cyclin A1
chr19_-_19302931 0.66 ENST00000444486.3
ENST00000514819.3
ENST00000585679.1
ENST00000162023.5
MEF2BNB-MEF2B readthrough
MEF2B neighbor
myocyte enhancer factor 2B
chr4_-_1723040 0.65 ENST00000382936.3
ENST00000536901.1
ENST00000303277.2
transmembrane protein 129
chr13_+_37005967 0.63 ENST00000440264.1
ENST00000449823.1
cyclin A1
chr19_+_41869894 0.62 ENST00000413014.2
transmembrane protein 91
chrM_+_10758 0.62 ENST00000361381.2
mitochondrially encoded NADH dehydrogenase 4
chr4_+_155702496 0.61 ENST00000510397.1
RNA binding motif protein 46
chr19_+_7694623 0.60 ENST00000594797.1
ENST00000456958.3
ENST00000601406.1
PET100 homolog (S. cerevisiae)
chr21_-_43916296 0.59 ENST00000398352.3
radial spoke head 1 homolog (Chlamydomonas)
chr9_+_1050331 0.58 ENST00000382255.3
ENST00000382251.3
ENST00000412350.2
doublesex and mab-3 related transcription factor 2
chr3_-_160823158 0.57 ENST00000392779.2
ENST00000392780.1
ENST00000494173.1
beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group)
chr12_-_22063787 0.57 ENST00000544039.1
ATP-binding cassette, sub-family C (CFTR/MRP), member 9
chr5_+_66300446 0.56 ENST00000261569.7
microtubule associated serine/threonine kinase family member 4
chr4_+_89513574 0.56 ENST00000402738.1
ENST00000431413.1
ENST00000422770.1
ENST00000407637.1
HECT and RLD domain containing E3 ubiquitin protein ligase 3
chr7_+_100210133 0.56 ENST00000393950.2
ENST00000424091.2
motile sperm domain containing 3
chr3_+_40498783 0.56 ENST00000338970.6
ENST00000396203.2
ENST00000416518.1
ribosomal protein L14
chr18_+_5238549 0.56 ENST00000580684.1
long intergenic non-protein coding RNA 667
chr6_-_33285505 0.56 ENST00000431845.2
zinc finger and BTB domain containing 22
chr5_+_66300464 0.56 ENST00000436277.1
microtubule associated serine/threonine kinase family member 4
chr3_+_102153859 0.55 ENST00000306176.1
ENST00000466937.1
zona pellucida-like domain containing 1
chr6_+_29691056 0.55 ENST00000414333.1
ENST00000334668.4
ENST00000259951.7
major histocompatibility complex, class I, F
chr1_+_28261621 0.54 ENST00000549094.1
sphingomyelin phosphodiesterase, acid-like 3B
chr2_+_220144052 0.53 ENST00000425450.1
ENST00000392086.4
ENST00000421532.1
DnaJ (Hsp40) homolog, subfamily B, member 2
chr19_+_12902289 0.53 ENST00000302754.4
jun B proto-oncogene
chr13_+_37006398 0.52 ENST00000418263.1
cyclin A1
chr14_-_76127519 0.52 ENST00000256319.6
chromosome 14 open reading frame 1
chr14_+_104182061 0.52 ENST00000216602.6
zinc finger, FYVE domain containing 21
chr22_+_41777927 0.50 ENST00000266304.4
thyrotrophic embryonic factor
chr17_-_47841485 0.50 ENST00000506156.1
ENST00000240364.2
family with sequence similarity 117, member A
chr18_-_65184217 0.49 ENST00000310045.7
dermatan sulfate epimerase-like
chr1_-_152386732 0.49 ENST00000271835.3
cornulin
chr2_+_242089833 0.47 ENST00000404405.3
ENST00000439916.1
ENST00000406106.3
ENST00000401987.1
protein phosphatase 1, regulatory subunit 7
chr2_+_201936458 0.47 ENST00000237889.4
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 3, 12kDa
chr4_-_69111401 0.46 ENST00000332644.5
transmembrane protease, serine 11B
chr3_-_99569821 0.46 ENST00000487087.1
filamin A interacting protein 1-like
chr6_-_31125850 0.46 ENST00000507751.1
ENST00000448162.2
ENST00000502557.1
ENST00000503420.1
ENST00000507892.1
ENST00000507226.1
ENST00000513222.1
ENST00000503934.1
ENST00000396263.2
ENST00000508683.1
ENST00000428174.1
ENST00000448141.2
ENST00000507829.1
ENST00000455279.2
ENST00000376266.5
coiled-coil alpha-helical rod protein 1
chr9_+_71944241 0.45 ENST00000257515.8
family with sequence similarity 189, member A2
chr7_-_64467031 0.45 ENST00000394323.2
endogenous retrovirus group 3, member 1
chr6_-_62996066 0.44 ENST00000281156.4
KH domain containing, RNA binding, signal transduction associated 2
chr10_+_24755416 0.44 ENST00000396446.1
ENST00000396445.1
ENST00000376451.2
KIAA1217
chr10_-_123274693 0.44 ENST00000429361.1
fibroblast growth factor receptor 2
chr7_+_100209725 0.44 ENST00000223054.4
motile sperm domain containing 3
chr7_+_100209979 0.43 ENST00000493970.1
ENST00000379527.2
motile sperm domain containing 3
chr11_-_33913708 0.43 ENST00000257818.2
LIM domain only 2 (rhombotin-like 1)
chr3_+_9439579 0.43 ENST00000406341.1
SET domain containing 5
chr3_+_156799587 0.42 ENST00000469196.1
RP11-6F2.5
chr17_+_74261413 0.42 ENST00000587913.1
UBA-like domain containing 2
chr7_+_37723450 0.42 ENST00000447769.1
G protein-coupled receptor 141
chr1_-_36906474 0.42 ENST00000433045.2
organic solute carrier partner 1
chr3_-_47018219 0.41 ENST00000292314.2
ENST00000546280.1
coiled-coil domain containing 12
chr17_-_73937028 0.41 ENST00000586631.2
Fas (TNFRSF6) binding factor 1
chr19_-_12833361 0.41 ENST00000592287.1
transportin 2
chr17_-_1531635 0.40 ENST00000571650.1
solute carrier family 43 (amino acid system L transporter), member 2
chr7_+_63505799 0.40 ENST00000550760.3
zinc finger protein 727
chr7_+_150782945 0.40 ENST00000463381.1
ArfGAP with GTPase domain, ankyrin repeat and PH domain 3
chr3_+_133292574 0.40 ENST00000264993.3
CDV3 homolog (mouse)
chr12_-_49418407 0.40 ENST00000526209.1
lysine (K)-specific methyltransferase 2D
chr16_+_29817399 0.39 ENST00000545521.1
MYC-associated zinc finger protein (purine-binding transcription factor)
chr3_+_85008089 0.39 ENST00000383699.3
cell adhesion molecule 2
chr6_+_130339710 0.39 ENST00000526087.1
ENST00000533560.1
ENST00000361794.2
l(3)mbt-like 3 (Drosophila)
chr17_-_72772462 0.39 ENST00000582870.1
ENST00000581136.1
ENST00000357814.3
ENST00000579218.1
ENST00000583476.1
ENST00000580301.1
ENST00000583757.1
ENST00000582524.1
N-acetyltransferase 9 (GCN5-related, putative)
chr20_+_32782375 0.38 ENST00000568305.1
agouti signaling protein
chr13_-_46626847 0.37 ENST00000242848.4
ENST00000282007.3
zinc finger CCCH-type containing 13
chr1_-_197036364 0.37 ENST00000367412.1
coagulation factor XIII, B polypeptide
chr4_-_103749205 0.37 ENST00000508249.1
ubiquitin-conjugating enzyme E2D 3
chr7_+_150929550 0.37 ENST00000482173.1
ENST00000495645.1
ENST00000035307.2
chondroitin polymerizing factor 2
chr11_+_57435219 0.37 ENST00000527985.1
ENST00000287169.3
zinc finger, DHHC-type containing 5
chr17_+_74733744 0.37 ENST00000586689.1
ENST00000587661.1
ENST00000593181.1
ENST00000336509.4
ENST00000355954.3
major facilitator superfamily domain containing 11
chr6_-_33385902 0.36 ENST00000374500.5
cutA divalent cation tolerance homolog (E. coli)
chr11_-_128894053 0.36 ENST00000392657.3
Rho GTPase activating protein 32
chr18_+_5238055 0.36 ENST00000582363.1
ENST00000582008.1
ENST00000580082.1
long intergenic non-protein coding RNA 667
chr13_+_19756173 0.36 ENST00000382988.2
RP11-408E5.4
chr14_+_104182105 0.35 ENST00000311141.2
zinc finger, FYVE domain containing 21
chr3_+_9439400 0.35 ENST00000450326.1
ENST00000402198.1
ENST00000402466.1
SET domain containing 5
chr6_-_138833630 0.35 ENST00000533765.1
NHS-like 1
chr10_+_103986085 0.35 ENST00000370005.3
ELOVL fatty acid elongase 3
chr14_+_99947715 0.34 ENST00000389879.5
ENST00000557441.1
ENST00000555049.1
ENST00000555842.1
cyclin K
chr10_+_13141441 0.34 ENST00000263036.5
optineurin
chr18_-_67624160 0.34 ENST00000581982.1
ENST00000280200.4
CD226 molecule
chr11_+_67798090 0.33 ENST00000313468.5
NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase)
chr20_+_49126881 0.33 ENST00000371621.3
ENST00000541713.1
protein tyrosine phosphatase, non-receptor type 1
chr4_+_144312659 0.32 ENST00000509992.1
GRB2-associated binding protein 1
chr4_+_144354644 0.32 ENST00000512843.1
GRB2-associated binding protein 1
chr17_+_80416482 0.32 ENST00000309794.11
ENST00000345415.7
ENST00000457415.3
ENST00000584411.1
ENST00000412079.2
ENST00000577432.1
nuclear prelamin A recognition factor
chr19_+_19303008 0.32 ENST00000353145.1
ENST00000421262.3
ENST00000303088.4
ENST00000456252.3
ENST00000593273.1
regulatory factor X-associated ankyrin-containing protein
chr10_+_13141585 0.30 ENST00000378764.2
optineurin
chr19_+_36239576 0.30 ENST00000587751.1
lin-37 homolog (C. elegans)
chr1_-_17766198 0.30 ENST00000375436.4
regulator of chromosome condensation 2
chr19_-_7694417 0.30 ENST00000358368.4
ENST00000534844.1
XPA binding protein 2
chr2_+_166095898 0.30 ENST00000424833.1
ENST00000375437.2
ENST00000357398.3
sodium channel, voltage-gated, type II, alpha subunit
chr16_+_31724552 0.29 ENST00000539915.1
ENST00000316491.9
ENST00000399681.3
ENST00000398696.3
ENST00000534369.1
zinc finger protein 720
chr3_-_105587879 0.29 ENST00000264122.4
ENST00000403724.1
ENST00000405772.1
Cbl proto-oncogene B, E3 ubiquitin protein ligase
chr16_+_31724618 0.29 ENST00000530881.1
ENST00000529515.1
zinc finger protein 720
chr5_-_159846399 0.29 ENST00000297151.4
SLU7 splicing factor homolog (S. cerevisiae)
chr19_-_10121144 0.28 ENST00000264828.3
collagen, type V, alpha 3
chr21_+_35014829 0.28 ENST00000451686.1
intersectin 1 (SH3 domain protein)
chr12_+_106751436 0.28 ENST00000228347.4
polymerase (RNA) III (DNA directed) polypeptide B
chr6_-_30585009 0.28 ENST00000376511.2
protein phosphatase 1, regulatory subunit 10
chr7_+_21582638 0.28 ENST00000409508.3
ENST00000328843.6
dynein, axonemal, heavy chain 11
chr4_-_110736505 0.28 ENST00000609440.1
RP11-602N24.3
chr6_-_33385870 0.27 ENST00000488034.1
cutA divalent cation tolerance homolog (E. coli)
chr12_-_2113583 0.27 ENST00000397173.4
ENST00000280665.6
decapping mRNA 1B
chr14_+_32798462 0.27 ENST00000280979.4
A kinase (PRKA) anchor protein 6
chr11_-_133826852 0.27 ENST00000533871.2
ENST00000321016.8
immunoglobulin superfamily, member 9B
chr6_-_27880174 0.26 ENST00000303324.2
olfactory receptor, family 2, subfamily B, member 2
chr17_+_59489112 0.26 ENST00000335108.2
chromosome 17 open reading frame 82
chr2_-_201936302 0.26 ENST00000453765.1
ENST00000452799.1
ENST00000446678.1
ENST00000418596.3
family with sequence similarity 126, member B
chr1_-_1709845 0.26 ENST00000341426.5
ENST00000344463.4
NAD kinase
chr1_-_1710229 0.26 ENST00000341991.3
NAD kinase
chr3_+_43020773 0.26 ENST00000488863.1
family with sequence similarity 198, member A
chr15_-_44116873 0.25 ENST00000267812.3
microfibrillar-associated protein 1
chr12_-_102455902 0.25 ENST00000240079.6
coiled-coil domain containing 53
chrX_+_49020882 0.25 ENST00000454342.1
MAGI family member, X-linked
chr2_+_113763031 0.25 ENST00000259211.6
interleukin 36, alpha
chr6_+_46661575 0.24 ENST00000450697.1
tudor domain containing 6
chr17_-_4871085 0.24 ENST00000575142.1
ENST00000206020.3
sperm associated antigen 7
chr1_+_81771806 0.24 ENST00000370721.1
ENST00000370727.1
ENST00000370725.1
ENST00000370723.1
ENST00000370728.1
ENST00000370730.1
latrophilin 2
chr6_-_33385655 0.24 ENST00000440279.3
ENST00000607266.1
cutA divalent cation tolerance homolog (E. coli)
chr10_+_13142225 0.24 ENST00000378747.3
optineurin
chr21_+_35014783 0.23 ENST00000381291.4
ENST00000381285.4
ENST00000399367.3
ENST00000399352.1
ENST00000399355.2
ENST00000399349.1
intersectin 1 (SH3 domain protein)
chr12_-_45270077 0.23 ENST00000551601.1
ENST00000549027.1
ENST00000452445.2
NEL-like 2 (chicken)
chr18_+_44526786 0.23 ENST00000245121.5
ENST00000356157.7
katanin p60 subunit A-like 2
chr19_-_10491234 0.23 ENST00000524462.1
ENST00000531836.1
ENST00000525621.1
tyrosine kinase 2
chr1_-_228613026 0.22 ENST00000366696.1
histone cluster 3, H3
chr22_-_39190116 0.22 ENST00000406622.1
ENST00000216068.4
ENST00000406199.3
Sad1 and UNC84 domain containing 2
dynein, axonemal, light chain 4
chr4_+_113558612 0.22 ENST00000505034.1
ENST00000324052.6
La ribonucleoprotein domain family, member 7
chr11_+_17298297 0.22 ENST00000529010.1
nucleobindin 2
chr7_-_140714739 0.22 ENST00000467334.1
ENST00000324787.5
mitochondrial ribosomal protein S33
chr11_-_121986923 0.22 ENST00000560104.1
BH3-like motif containing, cell death inducer
chr11_-_76155618 0.21 ENST00000530759.1
RP11-111M22.3
chr5_+_115358088 0.21 ENST00000600981.3
CTD-2287O16.3
chr6_-_33385854 0.21 ENST00000488478.1
cutA divalent cation tolerance homolog (E. coli)
chr18_+_60190226 0.21 ENST00000269499.5
zinc finger, CCHC domain containing 2
chr20_-_50418947 0.21 ENST00000371539.3
spalt-like transcription factor 4
chr10_+_71562180 0.21 ENST00000517713.1
ENST00000522165.1
ENST00000520133.1
collagen, type XIII, alpha 1
chr13_-_19755975 0.21 ENST00000400113.3
tubulin, alpha 3c
chr18_-_5238525 0.20 ENST00000581170.1
ENST00000579933.1
ENST00000581067.1
RP11-835E18.5
long intergenic non-protein coding RNA 526
chr3_+_156009623 0.20 ENST00000389634.5
potassium voltage-gated channel, shaker-related subfamily, beta member 1
chr1_+_28261492 0.20 ENST00000373894.3
sphingomyelin phosphodiesterase, acid-like 3B
chr4_+_74275057 0.20 ENST00000511370.1
albumin
chr9_+_34646624 0.19 ENST00000450095.2
ENST00000556278.1
galactose-1-phosphate uridylyltransferase
Uncharacterized protein
chr20_+_30467600 0.19 ENST00000375934.4
ENST00000375922.4
tubulin tyrosine ligase-like family, member 9
chr4_-_103749179 0.19 ENST00000502690.1
ubiquitin-conjugating enzyme E2D 3
chr12_-_102455846 0.19 ENST00000545679.1
coiled-coil domain containing 53
chr7_-_87342564 0.19 ENST00000265724.3
ENST00000416177.1
ATP-binding cassette, sub-family B (MDR/TAP), member 1
chr13_+_73632897 0.18 ENST00000377687.4
Kruppel-like factor 5 (intestinal)
chr12_-_45270151 0.18 ENST00000429094.2
NEL-like 2 (chicken)
chr20_-_50722183 0.18 ENST00000371523.4
ZFP64 zinc finger protein
chr11_+_67798114 0.18 ENST00000453471.2
ENST00000528492.1
ENST00000526339.1
ENST00000525419.1
NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase)
chr9_+_130565147 0.18 ENST00000373247.2
ENST00000373245.1
ENST00000393706.2
ENST00000373228.1
folylpolyglutamate synthase
chr1_-_13390765 0.18 ENST00000357367.2
PRAME family member 8
chr14_+_100842735 0.18 ENST00000554998.1
ENST00000402312.3
ENST00000335290.6
ENST00000554175.1
WD repeat domain 25
chr4_-_103749313 0.18 ENST00000394803.5
ubiquitin-conjugating enzyme E2D 3
chr1_-_205819245 0.17 ENST00000367136.4
peptidase M20 domain containing 1
chr9_+_117904097 0.17 ENST00000374016.1
deleted in esophageal cancer 1
chr19_-_14889349 0.17 ENST00000315576.3
ENST00000392967.2
ENST00000346057.1
ENST00000353876.1
ENST00000353005.1
egf-like module containing, mucin-like, hormone receptor-like 2
chr19_+_46236509 0.17 ENST00000457052.2
Uncharacterized protein
chr6_+_122931366 0.17 ENST00000368452.2
ENST00000368448.1
ENST00000392490.1
protein kinase (cAMP-dependent, catalytic) inhibitor beta
chr12_-_45269769 0.17 ENST00000548826.1
NEL-like 2 (chicken)
chr11_+_77532233 0.17 ENST00000525409.1
adipogenesis associated, Mth938 domain containing
chr12_-_45269430 0.16 ENST00000395487.2
NEL-like 2 (chicken)
chr17_-_40828969 0.16 ENST00000591022.1
ENST00000587627.1
ENST00000293349.6
pleckstrin homology domain containing, family H (with MyTH4 domain) member 3
chr17_-_40829026 0.16 ENST00000412503.1
pleckstrin homology domain containing, family H (with MyTH4 domain) member 3
chr14_+_21249200 0.16 ENST00000304677.2
ribonuclease, RNase A family, k6

Network of associatons between targets according to the STRING database.

First level regulatory network of LHX6

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.4 GO:1903644 regulation of chaperone-mediated protein folding(GO:1903644)
0.2 0.7 GO:0042270 antigen processing and presentation of endogenous peptide antigen via MHC class Ib(GO:0002476) protection from natural killer cell mediated cytotoxicity(GO:0042270)
0.2 1.2 GO:0033512 L-lysine catabolic process to acetyl-CoA via saccharopine(GO:0033512)
0.2 1.5 GO:0002480 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent(GO:0002480)
0.2 0.3 GO:2000646 positive regulation of receptor catabolic process(GO:2000646)
0.1 0.4 GO:0060667 fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow(GO:0035602) fibroblast growth factor receptor signaling pathway involved in hemopoiesis(GO:0035603) fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow(GO:0035604) fibroblast growth factor receptor signaling pathway involved in mammary gland specification(GO:0060595) mammary gland bud formation(GO:0060615) branch elongation involved in salivary gland morphogenesis(GO:0060667) mesenchymal cell differentiation involved in lung development(GO:0060915)
0.1 0.8 GO:0060005 vestibular reflex(GO:0060005)
0.1 1.1 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.1 0.3 GO:0006258 UDP-glucose catabolic process(GO:0006258)
0.1 0.5 GO:0008204 ergosterol biosynthetic process(GO:0006696) ergosterol metabolic process(GO:0008204)
0.1 0.3 GO:0072356 chromosome passenger complex localization to kinetochore(GO:0072356)
0.1 0.3 GO:0000349 generation of catalytic spliceosome for first transesterification step(GO:0000349)
0.1 2.7 GO:0002347 response to tumor cell(GO:0002347)
0.1 0.9 GO:0071896 protein localization to adherens junction(GO:0071896)
0.1 2.2 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.1 0.6 GO:0061055 myotome development(GO:0061055)
0.1 0.8 GO:0036072 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.1 1.3 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.1 0.9 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.1 0.3 GO:0044828 negative regulation by host of viral genome replication(GO:0044828)
0.1 0.4 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.1 0.7 GO:1900113 negative regulation of histone H3-K9 trimethylation(GO:1900113)
0.1 0.2 GO:0044179 hemolysis by symbiont of host erythrocytes(GO:0019836) hemolysis in other organism(GO:0044179) hemolysis in other organism involved in symbiotic interaction(GO:0052331)
0.1 0.4 GO:0001555 oocyte growth(GO:0001555)
0.1 0.5 GO:0006741 NADP biosynthetic process(GO:0006741)
0.1 0.7 GO:0006657 CDP-choline pathway(GO:0006657)
0.1 0.8 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.1 0.2 GO:0046901 tetrahydrofolylpolyglutamate biosynthetic process(GO:0046901)
0.1 0.5 GO:0060136 embryonic process involved in female pregnancy(GO:0060136)
0.1 0.9 GO:1990440 positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)
0.0 1.7 GO:0007141 male meiosis I(GO:0007141)
0.0 1.7 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0 0.0 GO:1904933 regulation of cell proliferation in midbrain(GO:1904933)
0.0 1.3 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.0 0.7 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.0 0.2 GO:0043605 cellular amide catabolic process(GO:0043605)
0.0 2.2 GO:0060512 prostate gland morphogenesis(GO:0060512)
0.0 0.4 GO:0008343 adult feeding behavior(GO:0008343)
0.0 0.2 GO:0048241 epinephrine transport(GO:0048241)
0.0 0.2 GO:1901529 positive regulation of anion channel activity(GO:1901529)
0.0 0.3 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
0.0 1.3 GO:0032461 positive regulation of protein oligomerization(GO:0032461)
0.0 1.1 GO:0090140 regulation of mitochondrial fission(GO:0090140)
0.0 0.3 GO:0019368 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 2.4 GO:0070206 protein trimerization(GO:0070206)
0.0 0.6 GO:0033617 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.0 0.4 GO:0003356 regulation of cilium beat frequency(GO:0003356)
0.0 0.3 GO:0097475 motor neuron migration(GO:0097475)
0.0 0.5 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.0 0.2 GO:0031022 nuclear migration along microfilament(GO:0031022)
0.0 0.3 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.0 1.9 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 1.5 GO:0015804 neutral amino acid transport(GO:0015804)
0.0 0.8 GO:0090036 regulation of protein kinase C signaling(GO:0090036)
0.0 0.6 GO:0001829 trophectodermal cell differentiation(GO:0001829)
0.0 1.2 GO:0035082 axoneme assembly(GO:0035082)
0.0 0.4 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
0.0 0.1 GO:0014901 regulation of satellite cell activation involved in skeletal muscle regeneration(GO:0014717) satellite cell activation involved in skeletal muscle regeneration(GO:0014901)
0.0 0.2 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.0 1.7 GO:0030574 collagen catabolic process(GO:0030574)
0.0 0.3 GO:0008627 intrinsic apoptotic signaling pathway in response to osmotic stress(GO:0008627)
0.0 1.7 GO:0010633 negative regulation of epithelial cell migration(GO:0010633)
0.0 0.3 GO:0043249 erythrocyte maturation(GO:0043249)
0.0 0.1 GO:1902498 regulation of protein autoubiquitination(GO:1902498)
0.0 0.1 GO:0090080 positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)
0.0 0.0 GO:0090108 positive regulation of high-density lipoprotein particle assembly(GO:0090108) positive regulation of secretion of lysosomal enzymes(GO:0090340)
0.0 0.4 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.0 0.6 GO:0035728 response to hepatocyte growth factor(GO:0035728)
0.0 0.1 GO:0061732 mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
0.0 0.4 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.0 0.7 GO:0030970 retrograde protein transport, ER to cytosol(GO:0030970)
0.0 0.9 GO:0006458 'de novo' protein folding(GO:0006458)
0.0 0.1 GO:0015760 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.0 0.5 GO:0030511 positive regulation of transforming growth factor beta receptor signaling pathway(GO:0030511) positive regulation of cellular response to transforming growth factor beta stimulus(GO:1903846)
0.0 0.3 GO:0098828 positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.0 0.1 GO:0032596 protein transport into membrane raft(GO:0032596)
0.0 0.2 GO:0060539 diaphragm development(GO:0060539)
0.0 0.4 GO:0018345 protein palmitoylation(GO:0018345)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.8 GO:0097123 cyclin A1-CDK2 complex(GO:0097123)
0.2 2.2 GO:0042612 MHC class I protein complex(GO:0042612)
0.1 0.3 GO:0002945 cyclin K-CDK12 complex(GO:0002944) cyclin K-CDK13 complex(GO:0002945)
0.1 0.5 GO:0005600 collagen type XIII trimer(GO:0005600) transmembrane collagen trimer(GO:0030936)
0.1 0.3 GO:0005588 collagen type V trimer(GO:0005588)
0.1 0.4 GO:0036338 viral envelope(GO:0019031) viral membrane(GO:0036338)
0.1 1.3 GO:0001520 outer dense fiber(GO:0001520)
0.1 0.6 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.1 0.9 GO:0098647 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.1 0.8 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.1 0.5 GO:0035976 AP1 complex(GO:0035976)
0.1 0.9 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.0 1.7 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.4 GO:0005638 lamin filament(GO:0005638)
0.0 0.3 GO:0071012 catalytic step 1 spliceosome(GO:0071012)
0.0 0.3 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.0 2.7 GO:0015030 Cajal body(GO:0015030)
0.0 0.1 GO:0097224 sperm connecting piece(GO:0097224)
0.0 0.4 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 0.2 GO:1990635 proximal dendrite(GO:1990635)
0.0 1.9 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.7 GO:0005721 pericentric heterochromatin(GO:0005721)
0.0 0.2 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 0.6 GO:0031304 intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305)
0.0 0.3 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.0 0.3 GO:0097539 ciliary transition fiber(GO:0097539)
0.0 0.3 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.0 0.3 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 1.6 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 0.3 GO:0060077 inhibitory synapse(GO:0060077)
0.0 0.2 GO:0033391 chromatoid body(GO:0033391)
0.0 0.1 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.0 0.1 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.0 0.1 GO:0033165 interphotoreceptor matrix(GO:0033165)
0.0 0.3 GO:1990023 mitotic spindle midzone(GO:1990023)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.3 GO:0047273 galactosylgalactosylglucosylceramide beta-D-acetylgalactosaminyltransferase activity(GO:0047273)
0.2 1.5 GO:0046979 TAP2 binding(GO:0046979)
0.1 0.7 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.1 0.6 GO:0008281 sulfonylurea receptor activity(GO:0008281)
0.1 0.9 GO:0000285 1-phosphatidylinositol-3-phosphate 5-kinase activity(GO:0000285)
0.1 0.5 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.1 2.2 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.1 0.7 GO:0030881 beta-2-microglobulin binding(GO:0030881)
0.1 0.4 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.1 0.4 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.1 0.8 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.1 0.2 GO:0008841 tetrahydrofolylpolyglutamate synthase activity(GO:0004326) dihydrofolate synthase activity(GO:0008841)
0.1 0.2 GO:1901375 acetylcholine transmembrane transporter activity(GO:0005277) secondary active organic cation transmembrane transporter activity(GO:0008513) acetate ester transmembrane transporter activity(GO:1901375)
0.0 0.1 GO:0004346 glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.0 0.4 GO:0031779 melanocortin receptor binding(GO:0031779) type 3 melanocortin receptor binding(GO:0031781) type 4 melanocortin receptor binding(GO:0031782)
0.0 0.1 GO:0004739 pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.0 0.7 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 1.4 GO:0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor(GO:0016646)
0.0 0.4 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.0 2.3 GO:0003954 NADH dehydrogenase activity(GO:0003954)
0.0 0.2 GO:0090554 phosphatidylcholine-translocating ATPase activity(GO:0090554)
0.0 1.3 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 1.4 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.7 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0 0.3 GO:0102337 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.9 GO:0035497 cAMP response element binding(GO:0035497)
0.0 1.5 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.0 0.1 GO:0004566 beta-glucuronidase activity(GO:0004566)
0.0 0.1 GO:0050528 acyloxyacyl hydrolase activity(GO:0050528)
0.0 0.9 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 0.3 GO:0070569 uridylyltransferase activity(GO:0070569)
0.0 1.9 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 0.2 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 0.5 GO:0043495 protein anchor(GO:0043495)
0.0 0.1 GO:0004982 N-formyl peptide receptor activity(GO:0004982)
0.0 1.6 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0 0.1 GO:0000386 second spliceosomal transesterification activity(GO:0000386)
0.0 0.0 GO:0001133 RNA polymerase II transcription factor activity, sequence-specific transcription regulatory region DNA binding(GO:0001133)
0.0 2.5 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 2.3 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.3 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 0.2 GO:0005131 growth hormone receptor binding(GO:0005131)
0.0 0.5 GO:0070064 proline-rich region binding(GO:0070064)
0.0 5.1 GO:0060090 binding, bridging(GO:0060090)
0.0 0.5 GO:0003951 NAD+ kinase activity(GO:0003951)
0.0 0.4 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 0.3 GO:0001056 RNA polymerase III activity(GO:0001056)
0.0 0.4 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.3 GO:0005248 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0 0.1 GO:0003985 acetyl-CoA C-acetyltransferase activity(GO:0003985)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.3 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.1 1.8 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 3.5 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 3.0 SIG PIP3 SIGNALING IN B LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.0 2.2 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.7 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 1.5 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.0 0.7 NABA COLLAGENS Genes encoding collagen proteins

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.5 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.1 2.2 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.1 3.1 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.1 1.8 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.1 1.6 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
0.0 2.4 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF RAS Genes involved in CREB phosphorylation through the activation of Ras
0.0 1.3 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 1.4 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 0.4 REACTOME FGFR2C LIGAND BINDING AND ACTIVATION Genes involved in FGFR2c ligand binding and activation
0.0 0.4 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.0 0.7 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.0 1.5 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.4 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 1.3 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 0.6 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 0.6 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.0 0.3 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 0.2 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.0 0.3 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 0.6 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport