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SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for LHX8

Z-value: 0.38

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Transcription factors associated with LHX8

Gene Symbol Gene ID Gene Info
LHX8
ENSG00000162624.10 LIM homeobox 8

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
LHX8hg19_v2_chr1_+_75594119_75594119-0.671.3e-03Click!

Activity profile of LHX8 motif

Sorted Z-values of LHX8 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr6_+_116691001 1.16 ENST00000537543.1
DSE
dermatan sulfate epimerase
chr6_-_56507586 1.00 ENST00000439203.1
ENST00000518935.1
ENST00000446842.2
ENST00000370765.6
ENST00000244364.6
DST
dystonin
chr19_+_21688366 0.85 ENST00000358491.4
ENST00000597078.1
ZNF429
zinc finger protein 429
chr4_+_174089951 0.71 ENST00000512285.1
GALNT7
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 7 (GalNAc-T7)
chr7_-_20256965 0.69 ENST00000400331.5
ENST00000332878.4
MACC1
metastasis associated in colon cancer 1
chr4_-_68749745 0.67 ENST00000283916.6
TMPRSS11D
transmembrane protease, serine 11D
chr4_-_68749699 0.60 ENST00000545541.1
TMPRSS11D
transmembrane protease, serine 11D
chr9_-_21974820 0.58 ENST00000579122.1
ENST00000498124.1
CDKN2A
cyclin-dependent kinase inhibitor 2A
chr3_+_41236325 0.57 ENST00000426215.1
ENST00000405570.1
CTNNB1
catenin (cadherin-associated protein), beta 1, 88kDa
chr2_+_158114051 0.56 ENST00000259056.4
GALNT5
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 5 (GalNAc-T5)
chr11_-_118122996 0.56 ENST00000525386.1
ENST00000527472.1
ENST00000278949.4
MPZL3
myelin protein zero-like 3
chr3_+_195447738 0.51 ENST00000447234.2
ENST00000320736.6
ENST00000436408.1
MUC20
mucin 20, cell surface associated
chrX_+_56258844 0.51 ENST00000374928.3
KLF8
Kruppel-like factor 8
chr12_-_88974236 0.51 ENST00000228280.5
ENST00000552044.1
ENST00000357116.4
KITLG
KIT ligand
chr6_+_43543942 0.50 ENST00000372226.1
ENST00000443535.1
POLH
polymerase (DNA directed), eta
chr21_+_39644305 0.50 ENST00000398930.1
KCNJ15
potassium inwardly-rectifying channel, subfamily J, member 15
chr14_+_62164340 0.48 ENST00000557538.1
ENST00000539097.1
HIF1A
hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
chr17_-_76719638 0.45 ENST00000587308.1
CYTH1
cytohesin 1
chr1_+_109419804 0.45 ENST00000435475.1
GPSM2
G-protein signaling modulator 2
chr14_+_57046530 0.45 ENST00000536419.1
ENST00000538838.1
TMEM260
transmembrane protein 260
chr4_-_83812248 0.42 ENST00000514326.1
ENST00000505434.1
ENST00000503058.1
ENST00000348405.4
ENST00000505984.1
ENST00000513858.1
ENST00000508479.1
ENST00000443462.2
ENST00000508502.1
ENST00000509142.1
ENST00000432794.1
ENST00000448323.1
ENST00000326950.5
ENST00000311785.7
SEC31A
SEC31 homolog A (S. cerevisiae)
chr4_+_174089904 0.42 ENST00000265000.4
GALNT7
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 7 (GalNAc-T7)
chr9_-_179018 0.42 ENST00000431099.2
ENST00000382447.4
ENST00000382389.1
ENST00000377447.3
ENST00000314367.10
ENST00000356521.4
ENST00000382393.1
ENST00000377400.4
CBWD1
COBW domain containing 1
chr4_-_186125077 0.41 ENST00000458385.2
ENST00000514798.1
ENST00000296775.6
KIAA1430
KIAA1430
chr4_+_106631966 0.40 ENST00000360505.5
ENST00000510865.1
ENST00000509336.1
GSTCD
glutathione S-transferase, C-terminal domain containing
chr10_+_75668916 0.39 ENST00000481390.1
PLAU
plasminogen activator, urokinase
chr2_-_178128250 0.39 ENST00000448782.1
ENST00000446151.2
NFE2L2
nuclear factor, erythroid 2-like 2
chr4_-_153332886 0.39 ENST00000603841.1
FBXW7
F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
chr4_-_83812402 0.38 ENST00000395310.2
SEC31A
SEC31 homolog A (S. cerevisiae)
chr10_-_29923893 0.38 ENST00000355867.4
SVIL
supervillin
chr13_+_38923959 0.37 ENST00000379649.1
ENST00000239878.4
ENST00000437952.1
ENST00000379641.1
UFM1
ubiquitin-fold modifier 1
chr14_-_36990354 0.36 ENST00000518149.1
NKX2-1
NK2 homeobox 1
chr6_-_75828774 0.35 ENST00000493109.2
COL12A1
collagen, type XII, alpha 1
chr5_-_39270725 0.33 ENST00000512138.1
ENST00000512982.1
ENST00000540520.1
FYB
FYN binding protein
chr10_-_28571015 0.33 ENST00000375719.3
ENST00000375732.1
MPP7
membrane protein, palmitoylated 7 (MAGUK p55 subfamily member 7)
chr21_-_16254231 0.32 ENST00000412426.1
ENST00000418954.1
AF127936.7
AF127936.7
chr2_-_178128149 0.31 ENST00000423513.1
NFE2L2
nuclear factor, erythroid 2-like 2
chr15_-_43785274 0.31 ENST00000413546.1
TP53BP1
tumor protein p53 binding protein 1
chr12_+_26205496 0.30 ENST00000537946.1
ENST00000541218.1
ENST00000282884.9
ENST00000545413.1
RASSF8
Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
chr1_+_145293371 0.30 ENST00000342960.5
NBPF10
neuroblastoma breakpoint family, member 10
chr2_+_114195268 0.29 ENST00000259199.4
ENST00000416503.2
ENST00000433343.2
CBWD2
COBW domain containing 2
chr12_+_97306295 0.28 ENST00000457368.2
NEDD1
neural precursor cell expressed, developmentally down-regulated 1
chr16_-_15149828 0.28 ENST00000566419.1
ENST00000568320.1
NTAN1
N-terminal asparagine amidase
chr10_+_24738355 0.27 ENST00000307544.6
KIAA1217
KIAA1217
chr16_-_53737722 0.26 ENST00000569716.1
ENST00000562588.1
ENST00000562230.1
ENST00000379925.3
ENST00000563746.1
ENST00000568653.3
RPGRIP1L
RPGRIP1-like
chr12_+_14572070 0.26 ENST00000545769.1
ENST00000428217.2
ENST00000396279.2
ENST00000542514.1
ENST00000536279.1
ATF7IP
activating transcription factor 7 interacting protein
chr2_-_178128528 0.26 ENST00000397063.4
ENST00000421929.1
NFE2L2
nuclear factor, erythroid 2-like 2
chr18_+_71815743 0.25 ENST00000169551.6
ENST00000580087.1
TIMM21
translocase of inner mitochondrial membrane 21 homolog (yeast)
chr18_-_74839891 0.25 ENST00000581878.1
MBP
myelin basic protein
chr5_-_24645078 0.25 ENST00000264463.4
CDH10
cadherin 10, type 2 (T2-cadherin)
chr1_+_160370344 0.25 ENST00000368061.2
VANGL2
VANGL planar cell polarity protein 2
chr7_+_151791095 0.25 ENST00000422997.2
GALNT11
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 11 (GalNAc-T11)
chr9_-_13165457 0.25 ENST00000542239.1
ENST00000538841.1
ENST00000433359.2
MPDZ
multiple PDZ domain protein
chr11_+_59480899 0.25 ENST00000300150.7
STX3
syntaxin 3
chr2_-_178128199 0.25 ENST00000449627.1
NFE2L2
nuclear factor, erythroid 2-like 2
chr15_-_44116873 0.24 ENST00000267812.3
MFAP1
microfibrillar-associated protein 1
chrX_+_108779870 0.23 ENST00000372107.1
NXT2
nuclear transport factor 2-like export factor 2
chr16_-_15149917 0.22 ENST00000287706.3
NTAN1
N-terminal asparagine amidase
chr1_-_95391315 0.22 ENST00000545882.1
ENST00000415017.1
CNN3
calponin 3, acidic
chr19_+_21203426 0.22 ENST00000261560.5
ENST00000599548.1
ENST00000594110.1
ZNF430
zinc finger protein 430
chr17_-_57229155 0.21 ENST00000584089.1
SKA2
spindle and kinetochore associated complex subunit 2
chr9_-_70490107 0.21 ENST00000377395.4
ENST00000429800.2
ENST00000430059.2
ENST00000377384.1
ENST00000382405.3
CBWD5
COBW domain containing 5
chr22_+_29876197 0.20 ENST00000310624.6
NEFH
neurofilament, heavy polypeptide
chr3_+_42977846 0.20 ENST00000383748.4
KRBOX1
KRAB box domain containing 1
chr5_-_150473127 0.20 ENST00000521001.1
TNIP1
TNFAIP3 interacting protein 1
chr9_+_70856397 0.20 ENST00000360171.6
CBWD3
COBW domain containing 3
chr1_+_92632542 0.20 ENST00000409154.4
ENST00000370378.4
KIAA1107
KIAA1107
chr10_+_127585118 0.20 ENST00000449042.2
FANK1
fibronectin type III and ankyrin repeat domains 1
chr6_+_76599809 0.20 ENST00000430435.1
MYO6
myosin VI
chr7_+_151791074 0.20 ENST00000447796.1
GALNT11
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 11 (GalNAc-T11)
chr9_-_69262509 0.20 ENST00000377449.1
ENST00000382399.4
ENST00000377439.1
ENST00000377441.1
ENST00000377457.5
CBWD6
COBW domain containing 6
chr9_+_70856899 0.19 ENST00000377342.5
ENST00000478048.1
CBWD3
COBW domain containing 3
chrX_-_73051037 0.19 ENST00000445814.1
XIST
X inactive specific transcript (non-protein coding)
chr4_+_26344754 0.19 ENST00000515573.1
RBPJ
recombination signal binding protein for immunoglobulin kappa J region
chr3_-_57199397 0.19 ENST00000296318.7
IL17RD
interleukin 17 receptor D
chr2_+_171640291 0.19 ENST00000409885.1
ERICH2
glutamate-rich 2
chr8_-_141810634 0.18 ENST00000521986.1
ENST00000523539.1
ENST00000538769.1
PTK2
protein tyrosine kinase 2
chr2_+_102758271 0.18 ENST00000428279.1
IL1R1
interleukin 1 receptor, type I
chr7_+_115862858 0.18 ENST00000393481.2
TES
testis derived transcript (3 LIM domains)
chr3_+_119187785 0.18 ENST00000295588.4
ENST00000476573.1
POGLUT1
protein O-glucosyltransferase 1
chr15_-_40074996 0.17 ENST00000350221.3
FSIP1
fibrous sheath interacting protein 1
chr3_-_52804872 0.17 ENST00000535191.1
ENST00000461689.1
ENST00000383721.4
ENST00000233027.5
NEK4
NIMA-related kinase 4
chr11_+_44117219 0.17 ENST00000532479.1
ENST00000527014.1
EXT2
exostosin glycosyltransferase 2
chr3_-_187455680 0.16 ENST00000438077.1
BCL6
B-cell CLL/lymphoma 6
chrX_-_117119243 0.16 ENST00000539496.1
ENST00000469946.1
KLHL13
kelch-like family member 13
chr14_+_57046500 0.16 ENST00000261556.6
TMEM260
transmembrane protein 260
chr7_+_30589829 0.16 ENST00000579437.1
RP4-777O23.1
RP4-777O23.1
chr15_-_34610962 0.16 ENST00000290209.5
SLC12A6
solute carrier family 12 (potassium/chloride transporter), member 6
chr19_-_10697895 0.15 ENST00000591240.1
ENST00000589684.1
ENST00000591676.1
ENST00000250244.6
ENST00000590923.1
AP1M2
adaptor-related protein complex 1, mu 2 subunit
chr9_+_96846740 0.15 ENST00000288976.3
PTPDC1
protein tyrosine phosphatase domain containing 1
chr19_+_21264980 0.14 ENST00000596053.1
ENST00000597086.1
ENST00000596143.1
ENST00000596367.1
ENST00000601416.1
ZNF714
zinc finger protein 714
chr16_-_53737795 0.14 ENST00000262135.4
ENST00000564374.1
ENST00000566096.1
RPGRIP1L
RPGRIP1-like
chr13_-_37633567 0.14 ENST00000464744.1
SUPT20H
suppressor of Ty 20 homolog (S. cerevisiae)
chr2_+_87144738 0.14 ENST00000559485.1
RGPD1
RANBP2-like and GRIP domain containing 1
chr11_-_117800080 0.14 ENST00000524993.1
ENST00000528626.1
ENST00000445164.2
ENST00000430170.2
ENST00000526090.1
TMPRSS13
transmembrane protease, serine 13
chr8_+_27168988 0.14 ENST00000397501.1
ENST00000338238.4
ENST00000544172.1
PTK2B
protein tyrosine kinase 2 beta
chr7_-_140482926 0.14 ENST00000496384.2
BRAF
v-raf murine sarcoma viral oncogene homolog B
chr19_-_4535233 0.14 ENST00000381848.3
ENST00000588887.1
ENST00000586133.1
PLIN5
perilipin 5
chr7_+_151791037 0.14 ENST00000419245.1
GALNT11
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 11 (GalNAc-T11)
chr13_+_98605902 0.13 ENST00000460070.1
ENST00000481455.1
ENST00000261574.5
ENST00000493281.1
ENST00000463157.1
ENST00000471898.1
ENST00000489058.1
ENST00000481689.1
IPO5
importin 5
chr1_+_145883868 0.13 ENST00000447947.2
GPR89C
G protein-coupled receptor 89C
chr1_+_28696111 0.13 ENST00000373839.3
PHACTR4
phosphatase and actin regulator 4
chr14_+_101295638 0.13 ENST00000523671.2
MEG3
maternally expressed 3 (non-protein coding)
chr2_-_74618964 0.13 ENST00000417090.1
ENST00000409868.1
DCTN1
dynactin 1
chr9_-_139372141 0.13 ENST00000313050.7
SEC16A
SEC16 homolog A (S. cerevisiae)
chr1_+_224301787 0.12 ENST00000366862.5
ENST00000424254.2
FBXO28
F-box protein 28
chr4_+_57302297 0.12 ENST00000399688.3
ENST00000512576.1
PAICS
phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase
chr16_+_81772633 0.12 ENST00000566191.1
ENST00000565272.1
ENST00000563954.1
ENST00000565054.1
RP11-960L18.1
PLCG2
RP11-960L18.1
phospholipase C, gamma 2 (phosphatidylinositol-specific)
chr3_+_154798162 0.12 ENST00000360490.2
MME
membrane metallo-endopeptidase
chr16_+_22217577 0.12 ENST00000263026.5
EEF2K
eukaryotic elongation factor-2 kinase
chr15_-_43785303 0.12 ENST00000382039.3
ENST00000450115.2
ENST00000382044.4
TP53BP1
tumor protein p53 binding protein 1
chr12_+_45686457 0.12 ENST00000441606.2
ANO6
anoctamin 6
chr20_+_30458431 0.12 ENST00000375938.4
ENST00000535842.1
ENST00000310998.4
ENST00000375921.2
TTLL9
tubulin tyrosine ligase-like family, member 9
chr7_-_127671674 0.12 ENST00000478726.1
LRRC4
leucine rich repeat containing 4
chr2_+_87135076 0.12 ENST00000409776.2
RGPD1
RANBP2-like and GRIP domain containing 1
chr1_+_53662101 0.12 ENST00000371486.3
CPT2
carnitine palmitoyltransferase 2
chr1_+_113009163 0.11 ENST00000256640.5
WNT2B
wingless-type MMTV integration site family, member 2B
chr5_-_130868688 0.11 ENST00000504575.1
ENST00000513227.1
RAPGEF6
Rap guanine nucleotide exchange factor (GEF) 6
chr8_-_27168737 0.11 ENST00000521253.1
ENST00000305364.4
TRIM35
tripartite motif containing 35
chr21_-_33984456 0.11 ENST00000431216.1
ENST00000553001.1
ENST00000440966.1
AP000275.65
C21orf59
Uncharacterized protein
chromosome 21 open reading frame 59
chr18_-_14132422 0.11 ENST00000589498.1
ENST00000590202.1
ZNF519
zinc finger protein 519
chr17_+_45000483 0.11 ENST00000576910.2
ENST00000439730.2
ENST00000393456.2
ENST00000415811.2
ENST00000575949.1
ENST00000225567.4
ENST00000572403.1
ENST00000570879.1
GOSR2
golgi SNAP receptor complex member 2
chr8_+_75262629 0.11 ENST00000434412.2
GDAP1
ganglioside induced differentiation associated protein 1
chr12_-_39734783 0.11 ENST00000552961.1
KIF21A
kinesin family member 21A
chr5_+_41904431 0.11 ENST00000381647.2
C5orf51
chromosome 5 open reading frame 51
chrX_+_70798261 0.11 ENST00000373696.3
ACRC
acidic repeat containing
chr2_+_109237717 0.11 ENST00000409441.1
LIMS1
LIM and senescent cell antigen-like domains 1
chr6_+_26087646 0.10 ENST00000309234.6
HFE
hemochromatosis
chr2_-_88285309 0.10 ENST00000420840.2
RGPD2
RANBP2-like and GRIP domain containing 2
chr6_+_26251835 0.10 ENST00000356350.2
HIST1H2BH
histone cluster 1, H2bh
chr17_-_76719807 0.10 ENST00000589297.1
CYTH1
cytohesin 1
chr1_-_168464875 0.10 ENST00000422253.1
RP5-968D22.3
RP5-968D22.3
chr15_-_75918787 0.10 ENST00000564086.1
SNUPN
snurportin 1
chr3_-_149470229 0.09 ENST00000473414.1
COMMD2
COMM domain containing 2
chr15_+_65843130 0.09 ENST00000569894.1
PTPLAD1
protein tyrosine phosphatase-like A domain containing 1
chr3_+_127317945 0.09 ENST00000472731.1
MCM2
minichromosome maintenance complex component 2
chr4_-_100242549 0.09 ENST00000305046.8
ENST00000394887.3
ADH1B
alcohol dehydrogenase 1B (class I), beta polypeptide
chr4_+_76439095 0.08 ENST00000506261.1
THAP6
THAP domain containing 6
chr9_+_26956474 0.08 ENST00000429045.2
IFT74
intraflagellar transport 74 homolog (Chlamydomonas)
chr2_-_14541060 0.08 ENST00000418420.1
ENST00000417751.1
LINC00276
long intergenic non-protein coding RNA 276
chr20_+_56964169 0.08 ENST00000475243.1
VAPB
VAMP (vesicle-associated membrane protein)-associated protein B and C
chr4_-_36245561 0.08 ENST00000506189.1
ARAP2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr11_+_44117260 0.08 ENST00000358681.4
EXT2
exostosin glycosyltransferase 2
chr19_+_42300548 0.07 ENST00000344550.4
CEACAM3
carcinoembryonic antigen-related cell adhesion molecule 3
chr19_-_695427 0.07 ENST00000329267.7
PRSS57
protease, serine, 57
chr1_-_33502528 0.07 ENST00000354858.6
AK2
adenylate kinase 2
chr12_-_54982300 0.07 ENST00000547431.1
PPP1R1A
protein phosphatase 1, regulatory (inhibitor) subunit 1A
chr1_+_47603109 0.07 ENST00000371890.3
ENST00000294337.3
ENST00000371891.3
CYP4A22
cytochrome P450, family 4, subfamily A, polypeptide 22
chr4_-_186733363 0.07 ENST00000393523.2
ENST00000393528.3
ENST00000449407.2
SORBS2
sorbin and SH3 domain containing 2
chr7_-_6865826 0.07 ENST00000538180.1
CCZ1B
CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae)
chr6_+_32006042 0.07 ENST00000418967.2
CYP21A2
cytochrome P450, family 21, subfamily A, polypeptide 2
chr2_-_74619152 0.07 ENST00000440727.1
ENST00000409240.1
DCTN1
dynactin 1
chr1_-_247242048 0.07 ENST00000366503.2
ZNF670
zinc finger protein 670
chrX_+_13707235 0.07 ENST00000464506.1
RAB9A
RAB9A, member RAS oncogene family
chr2_+_234621551 0.06 ENST00000608381.1
ENST00000373414.3
UGT1A1
UGT1A5
UDP glucuronosyltransferase 1 family, polypeptide A8
UDP glucuronosyltransferase 1 family, polypeptide A5
chr8_-_18711866 0.06 ENST00000519851.1
PSD3
pleckstrin and Sec7 domain containing 3
chr16_+_82068585 0.06 ENST00000563491.1
HSD17B2
hydroxysteroid (17-beta) dehydrogenase 2
chr12_-_15038779 0.06 ENST00000228938.5
ENST00000539261.1
MGP
matrix Gla protein
chr1_+_70876926 0.06 ENST00000370938.3
ENST00000346806.2
CTH
cystathionase (cystathionine gamma-lyase)
chr5_-_75008244 0.06 ENST00000510798.1
ENST00000446329.2
POC5
POC5 centriolar protein
chr4_+_74718906 0.06 ENST00000226524.3
PF4V1
platelet factor 4 variant 1
chr1_-_149459549 0.06 ENST00000369175.3
FAM72C
family with sequence similarity 72, member C
chr10_-_70231639 0.05 ENST00000551118.2
ENST00000358410.3
ENST00000399180.2
ENST00000399179.2
DNA2
DNA replication helicase/nuclease 2
chr17_-_42144949 0.05 ENST00000591247.1
LSM12
LSM12 homolog (S. cerevisiae)
chr2_-_136678123 0.05 ENST00000422708.1
DARS
aspartyl-tRNA synthetase
chr8_+_27169138 0.05 ENST00000522338.1
PTK2B
protein tyrosine kinase 2 beta
chr11_+_44117099 0.05 ENST00000533608.1
EXT2
exostosin glycosyltransferase 2
chr2_+_102758210 0.05 ENST00000450319.1
IL1R1
interleukin 1 receptor, type I
chr9_+_26956371 0.05 ENST00000380062.5
ENST00000518614.1
IFT74
intraflagellar transport 74 homolog (Chlamydomonas)
chrX_+_84258832 0.05 ENST00000373173.2
APOOL
apolipoprotein O-like
chr3_-_107099454 0.05 ENST00000593837.1
ENST00000599431.1
RP11-446H18.5
RP11-446H18.5
chr9_-_5833027 0.04 ENST00000339450.5
ERMP1
endoplasmic reticulum metallopeptidase 1
chr19_+_44716678 0.04 ENST00000586228.1
ENST00000588219.1
ENST00000313040.7
ENST00000589707.1
ENST00000588394.1
ENST00000589005.1
ZNF227
zinc finger protein 227
chr21_-_34863998 0.04 ENST00000402202.1
ENST00000381947.3
DNAJC28
DnaJ (Hsp40) homolog, subfamily C, member 28
chr6_+_154360616 0.04 ENST00000229768.5
ENST00000419506.2
ENST00000524163.1
ENST00000414028.2
ENST00000435918.2
ENST00000337049.4
OPRM1
opioid receptor, mu 1
chr3_-_119182523 0.04 ENST00000319172.5
TMEM39A
transmembrane protein 39A
chr22_+_23487513 0.04 ENST00000263116.2
ENST00000341989.4
RAB36
RAB36, member RAS oncogene family
chr2_+_201994042 0.04 ENST00000417748.1
CFLAR
CASP8 and FADD-like apoptosis regulator
chr7_+_7811992 0.04 ENST00000406829.1
RPA3-AS1
RPA3 antisense RNA 1
chr19_+_12175535 0.03 ENST00000550826.1
ZNF844
zinc finger protein 844
chr4_-_109684120 0.03 ENST00000512646.1
ENST00000411864.2
ENST00000296486.3
ENST00000510706.1
ETNPPL
ethanolamine-phosphate phospho-lyase
chr2_+_128377550 0.03 ENST00000437387.1
ENST00000409090.1
MYO7B
myosin VIIB
chrX_+_73164167 0.03 ENST00000414209.1
ENST00000602895.1
ENST00000453317.1
ENST00000602546.1
ENST00000602985.1
ENST00000415215.1
JPX
JPX transcript, XIST activator (non-protein coding)
chr18_-_11908329 0.03 ENST00000344987.7
ENST00000588103.1
ENST00000588191.1
ENST00000317235.7
ENST00000309976.9
ENST00000588186.1
ENST00000589267.1
MPPE1
metallophosphoesterase 1
chr18_-_11908272 0.03 ENST00000592977.1
ENST00000590501.1
ENST00000586844.1
MPPE1
metallophosphoesterase 1
chr3_-_47934234 0.03 ENST00000420772.2
MAP4
microtubule-associated protein 4
chr11_-_66964638 0.03 ENST00000444002.2
AP001885.1
AP001885.1
chr12_+_48516463 0.03 ENST00000546465.1
PFKM
phosphofructokinase, muscle
chr2_+_185463093 0.03 ENST00000302277.6
ZNF804A
zinc finger protein 804A
chr1_-_146040968 0.03 ENST00000401010.3
NBPF11
neuroblastoma breakpoint family, member 11
chr8_-_62602327 0.03 ENST00000445642.3
ENST00000517847.2
ENST00000389204.4
ENST00000517661.1
ENST00000517903.1
ENST00000522603.1
ENST00000522349.1
ENST00000522835.1
ENST00000541428.1
ENST00000518306.1
ASPH
aspartate beta-hydroxylase
chr6_+_26087509 0.02 ENST00000397022.3
ENST00000353147.5
ENST00000352392.4
ENST00000349999.4
ENST00000317896.7
ENST00000357618.5
ENST00000470149.1
ENST00000336625.8
ENST00000461397.1
ENST00000488199.1
HFE
hemochromatosis
chr15_-_75918500 0.02 ENST00000569817.1
SNUPN
snurportin 1
chr8_+_9009296 0.02 ENST00000521718.1
RP11-10A14.4
Uncharacterized protein
chr7_+_2394445 0.02 ENST00000360876.4
ENST00000413917.1
ENST00000397011.2
EIF3B
eukaryotic translation initiation factor 3, subunit B
chr4_-_95264008 0.02 ENST00000295256.5
HPGDS
hematopoietic prostaglandin D synthase
chr2_-_152118352 0.02 ENST00000331426.5
RBM43
RNA binding motif protein 43
chr2_-_240969906 0.02 ENST00000402971.2
OR6B2
olfactory receptor, family 6, subfamily B, member 2
chr14_-_81425828 0.02 ENST00000555529.1
ENST00000556042.1
ENST00000556981.1
CEP128
centrosomal protein 128kDa
chr11_-_59612969 0.02 ENST00000541311.1
ENST00000257248.2
GIF
gastric intrinsic factor (vitamin B synthesis)

Network of associatons between targets according to the STRING database.

First level regulatory network of LHX8

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.2 GO:0018242 protein O-linked glycosylation via serine(GO:0018242)
0.2 1.2 GO:1903786 mycotoxin catabolic process(GO:0043387) aflatoxin catabolic process(GO:0046223) organic heteropentacyclic compound catabolic process(GO:1901377) regulation of glutathione biosynthetic process(GO:1903786) positive regulation of glutathione biosynthetic process(GO:1903788)
0.2 0.5 GO:0033024 mast cell homeostasis(GO:0033023) mast cell apoptotic process(GO:0033024) regulation of mast cell apoptotic process(GO:0033025) regulation of mast cell proliferation(GO:0070666) positive regulation of mast cell proliferation(GO:0070668)
0.1 0.6 GO:1904793 glial cell fate determination(GO:0007403) canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation(GO:0061324) regulation of chromatin-mediated maintenance of transcription(GO:1904499) positive regulation of chromatin-mediated maintenance of transcription(GO:1904501) regulation of euchromatin binding(GO:1904793)
0.1 0.4 GO:2000097 regulation of smooth muscle cell-matrix adhesion(GO:2000097)
0.1 0.5 GO:0021502 neural fold elevation formation(GO:0021502) elastin metabolic process(GO:0051541) epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030) positive regulation of chemokine-mediated signaling pathway(GO:0070101)
0.1 0.5 GO:0031291 Ran protein signal transduction(GO:0031291)
0.1 0.2 GO:0060489 orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490)
0.1 0.4 GO:2000638 regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
0.1 0.2 GO:0033693 neurofilament bundle assembly(GO:0033693)
0.1 1.0 GO:0008090 retrograde axonal transport(GO:0008090)
0.1 0.3 GO:0034334 adherens junction maintenance(GO:0034334)
0.1 0.5 GO:0071494 cellular response to UV-C(GO:0071494)
0.1 0.4 GO:1990564 protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.0 0.6 GO:0035986 senescence-associated heterochromatin focus assembly(GO:0035986)
0.0 0.1 GO:0035359 negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
0.0 0.6 GO:0018243 protein O-linked glycosylation via threonine(GO:0018243)
0.0 0.1 GO:0061386 closure of optic fissure(GO:0061386)
0.0 0.1 GO:0002589 regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002589) negative regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002590) positive regulation of iron ion transport(GO:0034758) positive regulation of iron ion transmembrane transport(GO:0034761) regulation of iron ion import(GO:1900390) regulation of ferrous iron import into cell(GO:1903989) positive regulation of ferrous iron import into cell(GO:1903991) regulation of ferrous iron binding(GO:1904432) positive regulation of ferrous iron binding(GO:1904434) regulation of transferrin receptor binding(GO:1904435) positive regulation of transferrin receptor binding(GO:1904437) regulation of ferrous iron import across plasma membrane(GO:1904438) positive regulation of ferrous iron import across plasma membrane(GO:1904440) response to iron ion starvation(GO:1990641)
0.0 0.3 GO:1904207 regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904207) positive regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904209)
0.0 1.2 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.0 0.2 GO:0044501 modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032)
0.0 0.2 GO:0032764 negative regulation of mast cell cytokine production(GO:0032764) negative regulation of isotype switching to IgE isotypes(GO:0048294)
0.0 0.1 GO:0034059 response to anoxia(GO:0034059)
0.0 0.2 GO:2000661 positive regulation of interleukin-1-mediated signaling pathway(GO:2000661)
0.0 0.1 GO:0051037 regulation of transcription involved in meiotic cell cycle(GO:0051037)
0.0 0.8 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 0.3 GO:0071896 protein localization to adherens junction(GO:0071896)
0.0 0.2 GO:0042539 hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
0.0 0.1 GO:0002316 follicular B cell differentiation(GO:0002316)
0.0 0.4 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.0 0.4 GO:0021759 globus pallidus development(GO:0021759)
0.0 0.1 GO:0097045 phosphatidylserine exposure on blood platelet(GO:0097045)
0.0 0.1 GO:0060424 foregut regionalization(GO:0060423) lung field specification(GO:0060424) lung induction(GO:0060492)
0.0 0.2 GO:2000538 regulation of cGMP-mediated signaling(GO:0010752) regulation of B cell chemotaxis(GO:2000537) positive regulation of B cell chemotaxis(GO:2000538)
0.0 0.2 GO:0098881 exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967)
0.0 0.1 GO:0061015 snRNA import into nucleus(GO:0061015)
0.0 0.2 GO:1901297 positive regulation of ephrin receptor signaling pathway(GO:1901189) positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068)
0.0 0.1 GO:2000301 negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.0 0.2 GO:0090063 positive regulation of microtubule nucleation(GO:0090063)
0.0 2.1 GO:0016266 O-glycan processing(GO:0016266)
0.0 0.6 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.0 0.3 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0 0.4 GO:0021670 lateral ventricle development(GO:0021670)
0.0 0.1 GO:0006172 ADP biosynthetic process(GO:0006172)
0.0 0.1 GO:0018352 protein-pyridoxal-5-phosphate linkage(GO:0018352)
0.0 0.0 GO:0048213 Golgi vesicle prefusion complex stabilization(GO:0048213)
0.0 0.1 GO:0070980 biphenyl catabolic process(GO:0070980)
0.0 0.1 GO:1902990 DNA replication, removal of RNA primer(GO:0043137) mitotic telomere maintenance via semi-conservative replication(GO:1902990)
0.0 0.1 GO:0006422 aspartyl-tRNA aminoacylation(GO:0006422)
0.0 0.2 GO:0038007 netrin-activated signaling pathway(GO:0038007)
0.0 0.1 GO:0071492 cellular response to UV-A(GO:0071492)
0.0 0.3 GO:0097034 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.0 0.2 GO:0051028 mRNA transport(GO:0051028)
0.0 0.0 GO:0032097 positive regulation of response to food(GO:0032097) positive regulation of appetite(GO:0032100)
0.0 0.1 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
0.0 0.1 GO:0002933 lipid hydroxylation(GO:0002933)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.0 GO:0031673 H zone(GO:0031673)
0.1 0.4 GO:0005595 collagen type XII trimer(GO:0005595)
0.1 0.4 GO:0005879 axonemal microtubule(GO:0005879)
0.1 0.6 GO:0070369 Scrib-APC-beta-catenin complex(GO:0034750) beta-catenin-TCF7L2 complex(GO:0070369)
0.1 0.2 GO:0060187 cell pole(GO:0060187)
0.1 0.2 GO:1990796 photoreceptor cell terminal bouton(GO:1990796)
0.1 0.4 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.0 0.6 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.0 0.3 GO:0043541 UDP-N-acetylglucosamine transferase complex(GO:0043541)
0.0 0.8 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.4 GO:0036449 microtubule minus-end(GO:0036449)
0.0 0.0 GO:0017119 Golgi transport complex(GO:0017119)
0.0 0.3 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.0 0.2 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0 0.5 GO:0097431 mitotic spindle pole(GO:0097431)
0.0 0.3 GO:0033269 internode region of axon(GO:0033269)
0.0 0.3 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.0 0.1 GO:1990357 terminal web(GO:1990357)
0.0 0.5 GO:0031528 microvillus membrane(GO:0031528)
0.0 0.2 GO:0005883 neurofilament(GO:0005883)
0.0 0.2 GO:0005869 dynactin complex(GO:0005869)
0.0 0.2 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.2 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.1 0.4 GO:0031862 prostanoid receptor binding(GO:0031862)
0.1 0.5 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.1 0.2 GO:0060001 minus-end directed microfilament motor activity(GO:0060001)
0.1 0.4 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.1 0.3 GO:0050509 N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity(GO:0050509)
0.1 0.2 GO:0030158 protein xylosyltransferase activity(GO:0030158)
0.1 2.3 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.4 GO:0050816 phosphothreonine binding(GO:0050816)
0.0 0.2 GO:0004909 interleukin-1, Type I, activating receptor activity(GO:0004909)
0.0 0.4 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.0 0.2 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.0 0.1 GO:0033149 FFAT motif binding(GO:0033149)
0.0 0.6 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0 0.5 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.0 0.2 GO:0050544 arachidonic acid binding(GO:0050544)
0.0 0.6 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 1.0 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.5 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 0.9 GO:0070840 dynein complex binding(GO:0070840)
0.0 0.2 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.0 0.1 GO:0035473 lipase binding(GO:0035473)
0.0 0.6 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 1.2 GO:0001221 transcription cofactor binding(GO:0001221)
0.0 0.1 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095)
0.0 0.1 GO:0030881 beta-2-microglobulin binding(GO:0030881)
0.0 0.1 GO:0072542 protein phosphatase activator activity(GO:0072542)
0.0 0.5 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.2 GO:0022820 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.0 0.0 GO:0016838 carbon-oxygen lyase activity, acting on phosphates(GO:0016838)
0.0 0.5 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 0.1 GO:0047006 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity(GO:0047006)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.1 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 0.6 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.0 0.4 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 0.8 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 2.2 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.5 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.0 0.1 REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION Genes involved in Influenza Viral RNA Transcription and Replication
0.0 0.7 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 1.2 REACTOME CHONDROITIN SULFATE DERMATAN SULFATE METABOLISM Genes involved in Chondroitin sulfate/dermatan sulfate metabolism
0.0 0.5 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 0.3 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0 0.3 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis