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SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for LMX1B_MNX1_RAX2

Z-value: 1.19

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Transcription factors associated with LMX1B_MNX1_RAX2

Gene Symbol Gene ID Gene Info
LMX1B
ENSG00000136944.13 LIM homeobox transcription factor 1 beta
MNX1
ENSG00000130675.10 motor neuron and pancreas homeobox 1
RAX2
ENSG00000173976.11 retina and anterior neural fold homeobox 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
MNX1hg19_v2_chr7_-_156803329_156803362-0.941.1e-09Click!
LMX1Bhg19_v2_chr9_+_129376722_129376748-0.941.4e-09Click!
RAX2hg19_v2_chr19_-_3772209_37722360.126.2e-01Click!

Activity profile of LMX1B_MNX1_RAX2 motif

Sorted Z-values of LMX1B_MNX1_RAX2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr12_-_28122980 11.60 ENST00000395868.3
ENST00000534890.1
PTHLH
parathyroid hormone-like hormone
chr12_-_28123206 10.57 ENST00000542963.1
ENST00000535992.1
PTHLH
parathyroid hormone-like hormone
chr11_+_35222629 8.92 ENST00000526553.1
CD44
CD44 molecule (Indian blood group)
chr3_-_151034734 7.96 ENST00000260843.4
GPR87
G protein-coupled receptor 87
chr5_+_31193847 6.67 ENST00000514738.1
ENST00000265071.2
CDH6
cadherin 6, type 2, K-cadherin (fetal kidney)
chr2_+_158114051 6.41 ENST00000259056.4
GALNT5
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 5 (GalNAc-T5)
chr4_+_169013666 4.95 ENST00000359299.3
ANXA10
annexin A10
chr5_+_66300464 4.84 ENST00000436277.1
MAST4
microtubule associated serine/threonine kinase family member 4
chr5_+_166711804 4.81 ENST00000518659.1
ENST00000545108.1
TENM2
teneurin transmembrane protein 2
chr14_+_72052983 4.63 ENST00000358550.2
SIPA1L1
signal-induced proliferation-associated 1 like 1
chr6_+_130339710 4.29 ENST00000526087.1
ENST00000533560.1
ENST00000361794.2
L3MBTL3
l(3)mbt-like 3 (Drosophila)
chr11_-_129062093 4.25 ENST00000310343.9
ARHGAP32
Rho GTPase activating protein 32
chr5_+_66300446 4.01 ENST00000261569.7
MAST4
microtubule associated serine/threonine kinase family member 4
chr4_+_69313145 3.97 ENST00000305363.4
TMPRSS11E
transmembrane protease, serine 11E
chr1_+_160370344 3.82 ENST00000368061.2
VANGL2
VANGL planar cell polarity protein 2
chr5_-_24645078 3.55 ENST00000264463.4
CDH10
cadherin 10, type 2 (T2-cadherin)
chr7_-_27169801 3.52 ENST00000511914.1
HOXA4
homeobox A4
chr1_+_68150744 3.22 ENST00000370986.4
ENST00000370985.3
GADD45A
growth arrest and DNA-damage-inducible, alpha
chr18_+_32173276 3.21 ENST00000591816.1
ENST00000588125.1
ENST00000598334.1
ENST00000588684.1
ENST00000554864.3
ENST00000399121.5
ENST00000595022.1
ENST00000269190.7
ENST00000399097.3
DTNA
dystrobrevin, alpha
chr1_-_152386732 3.14 ENST00000271835.3
CRNN
cornulin
chr15_+_93443419 3.13 ENST00000557381.1
ENST00000420239.2
CHD2
chromodomain helicase DNA binding protein 2
chr8_-_139926236 3.11 ENST00000303045.6
ENST00000435777.1
COL22A1
collagen, type XXII, alpha 1
chr13_-_86373536 2.86 ENST00000400286.2
SLITRK6
SLIT and NTRK-like family, member 6
chr3_+_111717511 2.73 ENST00000478951.1
ENST00000393917.2
TAGLN3
transgelin 3
chr19_-_51522955 2.62 ENST00000358789.3
KLK10
kallikrein-related peptidase 10
chr18_+_29027696 2.62 ENST00000257189.4
DSG3
desmoglein 3
chr9_+_2159850 2.36 ENST00000416751.1
SMARCA2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr6_-_32157947 2.34 ENST00000375050.4
PBX2
pre-B-cell leukemia homeobox 2
chr4_+_26324474 2.34 ENST00000514675.1
RBPJ
recombination signal binding protein for immunoglobulin kappa J region
chr7_+_23286182 2.30 ENST00000258733.4
ENST00000381990.2
ENST00000409458.3
ENST00000539136.1
ENST00000453162.2
GPNMB
glycoprotein (transmembrane) nmb
chr7_+_134464376 2.28 ENST00000454108.1
ENST00000361675.2
CALD1
caldesmon 1
chr3_+_111718036 2.24 ENST00000455401.2
TAGLN3
transgelin 3
chrM_+_10758 2.18 ENST00000361381.2
MT-ND4
mitochondrially encoded NADH dehydrogenase 4
chr3_-_12587055 2.16 ENST00000564146.3
C3orf83
chromosome 3 open reading frame 83
chrM_+_10464 2.06 ENST00000361335.1
MT-ND4L
mitochondrially encoded NADH dehydrogenase 4L
chr3_+_111717600 2.03 ENST00000273368.4
TAGLN3
transgelin 3
chr3_-_141747950 2.03 ENST00000497579.1
TFDP2
transcription factor Dp-2 (E2F dimerization partner 2)
chr4_-_36245561 2.02 ENST00000506189.1
ARAP2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr10_+_24497704 2.00 ENST00000376456.4
ENST00000458595.1
KIAA1217
KIAA1217
chr7_-_92777606 2.00 ENST00000437805.1
ENST00000446959.1
ENST00000439952.1
ENST00000414791.1
ENST00000446033.1
ENST00000411955.1
ENST00000318238.4
SAMD9L
sterile alpha motif domain containing 9-like
chr8_+_107460147 1.91 ENST00000442977.2
OXR1
oxidation resistance 1
chrM_-_14670 1.87 ENST00000361681.2
MT-ND6
mitochondrially encoded NADH dehydrogenase 6
chr4_+_3388057 1.86 ENST00000538395.1
RGS12
regulator of G-protein signaling 12
chr1_-_183538319 1.82 ENST00000420553.1
ENST00000419402.1
NCF2
neutrophil cytosolic factor 2
chr11_+_34663913 1.78 ENST00000532302.1
EHF
ets homologous factor
chr4_-_74486217 1.75 ENST00000335049.5
ENST00000307439.5
RASSF6
Ras association (RalGDS/AF-6) domain family member 6
chr16_+_53133070 1.74 ENST00000565832.1
CHD9
chromodomain helicase DNA binding protein 9
chr20_-_50722183 1.72 ENST00000371523.4
ZFP64
ZFP64 zinc finger protein
chr3_-_52090461 1.68 ENST00000296483.6
ENST00000495880.1
DUSP7
dual specificity phosphatase 7
chrM_+_10053 1.64 ENST00000361227.2
MT-ND3
mitochondrially encoded NADH dehydrogenase 3
chr19_-_51523412 1.63 ENST00000391805.1
ENST00000599077.1
KLK10
kallikrein-related peptidase 10
chr19_-_14064114 1.62 ENST00000585607.1
ENST00000538517.2
ENST00000587458.1
ENST00000538371.2
PODNL1
podocan-like 1
chr12_+_4385230 1.61 ENST00000536537.1
CCND2
cyclin D2
chr11_+_34664014 1.60 ENST00000527935.1
EHF
ets homologous factor
chr12_-_89746173 1.60 ENST00000308385.6
DUSP6
dual specificity phosphatase 6
chr4_+_159727272 1.55 ENST00000379346.3
FNIP2
folliculin interacting protein 2
chr4_+_169418255 1.53 ENST00000505667.1
ENST00000511948.1
PALLD
palladin, cytoskeletal associated protein
chr2_-_214016314 1.51 ENST00000434687.1
ENST00000374319.4
IKZF2
IKAROS family zinc finger 2 (Helios)
chr6_-_138833630 1.49 ENST00000533765.1
NHSL1
NHS-like 1
chr4_-_74486347 1.48 ENST00000342081.3
RASSF6
Ras association (RalGDS/AF-6) domain family member 6
chr2_-_207024233 1.46 ENST00000423725.1
ENST00000233190.6
NDUFS1
NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)
chr12_-_112123524 1.46 ENST00000327551.6
BRAP
BRCA1 associated protein
chr1_-_152131703 1.45 ENST00000316073.3
RPTN
repetin
chr19_-_51523275 1.42 ENST00000309958.3
KLK10
kallikrein-related peptidase 10
chr14_-_36988882 1.36 ENST00000498187.2
NKX2-1
NK2 homeobox 1
chrX_+_105936982 1.36 ENST00000418562.1
RNF128
ring finger protein 128, E3 ubiquitin protein ligase
chr2_+_17997763 1.32 ENST00000281047.3
MSGN1
mesogenin 1
chrM_+_3299 1.30 ENST00000361390.2
MT-ND1
mitochondrially encoded NADH dehydrogenase 1
chr18_-_33709268 1.28 ENST00000269187.5
ENST00000590986.1
ENST00000440549.2
SLC39A6
solute carrier family 39 (zinc transporter), member 6
chr10_+_24544249 1.28 ENST00000430453.2
KIAA1217
KIAA1217
chrM_+_7586 1.25 ENST00000361739.1
MT-CO2
mitochondrially encoded cytochrome c oxidase II
chr4_-_74486109 1.24 ENST00000395777.2
RASSF6
Ras association (RalGDS/AF-6) domain family member 6
chr6_-_138866823 1.24 ENST00000342260.5
NHSL1
NHS-like 1
chr16_-_4852915 1.23 ENST00000322048.7
ROGDI
rogdi homolog (Drosophila)
chr4_-_143226979 1.23 ENST00000514525.1
INPP4B
inositol polyphosphate-4-phosphatase, type II, 105kDa
chr3_+_111718173 1.23 ENST00000494932.1
TAGLN3
transgelin 3
chr1_+_154401791 1.19 ENST00000476006.1
IL6R
interleukin 6 receptor
chr17_+_41363854 1.18 ENST00000588693.1
ENST00000588659.1
ENST00000541594.1
ENST00000536052.1
ENST00000331615.3
TMEM106A
transmembrane protein 106A
chr3_-_74570291 1.18 ENST00000263665.6
CNTN3
contactin 3 (plasmacytoma associated)
chr1_+_154193643 1.17 ENST00000456325.1
UBAP2L
ubiquitin associated protein 2-like
chr4_-_143227088 1.17 ENST00000511838.1
INPP4B
inositol polyphosphate-4-phosphatase, type II, 105kDa
chrX_+_105937068 1.15 ENST00000324342.3
RNF128
ring finger protein 128, E3 ubiquitin protein ligase
chr4_-_39979576 1.15 ENST00000303538.8
ENST00000503396.1
PDS5A
PDS5, regulator of cohesion maintenance, homolog A (S. cerevisiae)
chr10_+_98741041 1.14 ENST00000286067.2
C10orf12
chromosome 10 open reading frame 12
chr4_+_71384257 1.09 ENST00000339336.4
AMTN
amelotin
chr17_+_18086392 1.09 ENST00000541285.1
ALKBH5
alkB, alkylation repair homolog 5 (E. coli)
chr1_-_36020531 1.08 ENST00000440579.1
ENST00000494948.1
KIAA0319L
KIAA0319-like
chr10_-_115904361 1.06 ENST00000428953.1
ENST00000543782.1
C10orf118
chromosome 10 open reading frame 118
chrX_+_134654540 1.04 ENST00000370752.4
DDX26B
DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 26B
chr7_-_84121858 1.04 ENST00000448879.1
SEMA3A
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr8_+_38831683 1.02 ENST00000302495.4
HTRA4
HtrA serine peptidase 4
chr2_-_207024134 1.02 ENST00000457011.1
ENST00000440274.1
ENST00000432169.1
NDUFS1
NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)
chr4_-_25865159 1.00 ENST00000502949.1
ENST00000264868.5
ENST00000513691.1
ENST00000514872.1
SEL1L3
sel-1 suppressor of lin-12-like 3 (C. elegans)
chr18_+_34124507 0.98 ENST00000591635.1
FHOD3
formin homology 2 domain containing 3
chr5_+_125758865 0.98 ENST00000542322.1
ENST00000544396.1
GRAMD3
GRAM domain containing 3
chr5_-_126409159 0.98 ENST00000607731.1
ENST00000535381.1
ENST00000296662.5
ENST00000509733.3
C5orf63
chromosome 5 open reading frame 63
chr1_+_174844645 0.97 ENST00000486220.1
RABGAP1L
RAB GTPase activating protein 1-like
chr7_+_134464414 0.96 ENST00000361901.2
CALD1
caldesmon 1
chr17_-_38859996 0.95 ENST00000264651.2
KRT24
keratin 24
chr13_-_46716969 0.94 ENST00000435666.2
LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr2_-_207023918 0.92 ENST00000455934.2
ENST00000449699.1
ENST00000454195.1
NDUFS1
NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)
chr2_+_68961934 0.91 ENST00000409202.3
ARHGAP25
Rho GTPase activating protein 25
chr5_+_125758813 0.90 ENST00000285689.3
ENST00000515200.1
GRAMD3
GRAM domain containing 3
chr1_+_12042015 0.90 ENST00000412236.1
MFN2
mitofusin 2
chr1_-_68698197 0.88 ENST00000370973.2
ENST00000370971.1
WLS
wntless Wnt ligand secretion mediator
chr4_+_71384300 0.87 ENST00000504451.1
AMTN
amelotin
chr3_+_107364769 0.86 ENST00000449271.1
ENST00000425868.1
ENST00000449213.1
BBX
bobby sox homolog (Drosophila)
chrM_+_14741 0.86 ENST00000361789.2
MT-CYB
mitochondrially encoded cytochrome b
chr1_-_68698222 0.85 ENST00000370976.3
ENST00000354777.2
ENST00000262348.4
ENST00000540432.1
WLS
wntless Wnt ligand secretion mediator
chr2_+_68961905 0.84 ENST00000295381.3
ARHGAP25
Rho GTPase activating protein 25
chr2_+_68962014 0.82 ENST00000467265.1
ARHGAP25
Rho GTPase activating protein 25
chr18_+_21572737 0.82 ENST00000304621.6
TTC39C
tetratricopeptide repeat domain 39C
chr14_-_38064198 0.81 ENST00000250448.2
FOXA1
forkhead box A1
chr5_+_140855495 0.81 ENST00000308177.3
PCDHGC3
protocadherin gamma subfamily C, 3
chr4_-_57547870 0.80 ENST00000381260.3
ENST00000420433.1
ENST00000554144.1
ENST00000557328.1
HOPX
HOP homeobox
chr8_-_116504448 0.80 ENST00000518018.1
TRPS1
trichorhinophalangeal syndrome I
chr8_+_105235572 0.79 ENST00000523362.1
RIMS2
regulating synaptic membrane exocytosis 2
chr4_-_87028478 0.79 ENST00000515400.1
ENST00000395157.3
MAPK10
mitogen-activated protein kinase 10
chr12_-_52967600 0.77 ENST00000549343.1
ENST00000305620.2
KRT74
keratin 74
chrY_+_15418467 0.77 ENST00000595988.1
AC010877.1
Uncharacterized protein
chr2_+_171034646 0.77 ENST00000409044.3
ENST00000408978.4
MYO3B
myosin IIIB
chr3_+_121774202 0.76 ENST00000469710.1
ENST00000493101.1
ENST00000330540.2
ENST00000264468.5
CD86
CD86 molecule
chr2_-_208031943 0.75 ENST00000421199.1
ENST00000457962.1
KLF7
Kruppel-like factor 7 (ubiquitous)
chr8_-_42358742 0.74 ENST00000517366.1
SLC20A2
solute carrier family 20 (phosphate transporter), member 2
chr1_+_61548374 0.74 ENST00000485903.2
ENST00000371185.2
ENST00000371184.2
NFIA
nuclear factor I/A
chr14_+_104182105 0.74 ENST00000311141.2
ZFYVE21
zinc finger, FYVE domain containing 21
chr4_-_186696425 0.73 ENST00000430503.1
ENST00000319454.6
ENST00000450341.1
SORBS2
sorbin and SH3 domain containing 2
chr1_+_155023757 0.73 ENST00000356955.2
ENST00000449910.2
ENST00000359280.4
ENST00000360674.4
ENST00000368412.3
ENST00000355956.2
ENST00000368410.2
ENST00000271836.6
ENST00000368413.1
ENST00000531455.1
ENST00000447332.3
ADAM15
ADAM metallopeptidase domain 15
chr19_+_13049413 0.73 ENST00000316448.5
ENST00000588454.1
CALR
calreticulin
chr12_-_89746264 0.73 ENST00000548755.1
DUSP6
dual specificity phosphatase 6
chr11_-_118023490 0.71 ENST00000324727.4
SCN4B
sodium channel, voltage-gated, type IV, beta subunit
chr17_+_61151306 0.69 ENST00000580068.1
ENST00000580466.1
TANC2
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
chr14_+_104182061 0.69 ENST00000216602.6
ZFYVE21
zinc finger, FYVE domain containing 21
chr6_-_39693111 0.68 ENST00000373215.3
ENST00000538893.1
ENST00000287152.7
ENST00000373216.3
KIF6
kinesin family member 6
chrM_+_8527 0.68 ENST00000361899.2
MT-ATP6
mitochondrially encoded ATP synthase 6
chr6_-_111927449 0.68 ENST00000368761.5
ENST00000392556.4
ENST00000340026.6
TRAF3IP2
TRAF3 interacting protein 2
chr3_+_130569429 0.67 ENST00000505330.1
ENST00000504381.1
ENST00000507488.2
ENST00000393221.4
ATP2C1
ATPase, Ca++ transporting, type 2C, member 1
chr16_+_69345243 0.66 ENST00000254950.11
VPS4A
vacuolar protein sorting 4 homolog A (S. cerevisiae)
chr13_-_36050819 0.64 ENST00000379919.4
MAB21L1
mab-21-like 1 (C. elegans)
chr17_+_72931876 0.63 ENST00000328801.4
OTOP3
otopetrin 3
chr1_+_107682629 0.63 ENST00000370074.4
ENST00000370073.2
ENST00000370071.2
ENST00000542803.1
ENST00000370061.3
ENST00000370072.3
ENST00000370070.2
NTNG1
netrin G1
chr5_+_125759140 0.62 ENST00000543198.1
GRAMD3
GRAM domain containing 3
chr13_-_99667960 0.60 ENST00000448493.2
DOCK9
dedicator of cytokinesis 9
chr1_-_168464875 0.59 ENST00000422253.1
RP5-968D22.3
RP5-968D22.3
chr13_-_41593425 0.58 ENST00000239882.3
ELF1
E74-like factor 1 (ets domain transcription factor)
chr2_+_170440844 0.57 ENST00000260970.3
ENST00000433207.1
ENST00000409714.3
ENST00000462903.1
PPIG
peptidylprolyl isomerase G (cyclophilin G)
chr3_-_138048682 0.57 ENST00000383180.2
NME9
NME/NM23 family member 9
chr16_+_30669720 0.56 ENST00000356166.6
FBRS
fibrosin
chr14_-_75083313 0.55 ENST00000556652.1
ENST00000555313.1
CTD-2207P18.2
CTD-2207P18.2
chr12_+_14561422 0.55 ENST00000541056.1
ATF7IP
activating transcription factor 7 interacting protein
chr15_-_53002007 0.55 ENST00000561490.1
FAM214A
family with sequence similarity 214, member A
chr3_+_107364683 0.55 ENST00000413213.1
BBX
bobby sox homolog (Drosophila)
chr4_-_76944621 0.52 ENST00000306602.1
CXCL10
chemokine (C-X-C motif) ligand 10
chr5_+_67586465 0.52 ENST00000336483.5
PIK3R1
phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
chr4_-_186696561 0.51 ENST00000445115.1
ENST00000451701.1
ENST00000457247.1
ENST00000435480.1
ENST00000425679.1
ENST00000457934.1
SORBS2
sorbin and SH3 domain containing 2
chr12_+_93096619 0.50 ENST00000397833.3
C12orf74
chromosome 12 open reading frame 74
chr3_-_78719376 0.50 ENST00000495961.1
ROBO1
roundabout, axon guidance receptor, homolog 1 (Drosophila)
chr21_-_42219065 0.50 ENST00000400454.1
DSCAM
Down syndrome cell adhesion molecule
chr3_+_15045419 0.49 ENST00000406272.2
NR2C2
nuclear receptor subfamily 2, group C, member 2
chr12_-_91546926 0.49 ENST00000550758.1
DCN
decorin
chr18_+_32402321 0.48 ENST00000587723.1
DTNA
dystrobrevin, alpha
chr18_+_46065393 0.48 ENST00000256413.3
CTIF
CBP80/20-dependent translation initiation factor
chr8_-_101733794 0.47 ENST00000523555.1
PABPC1
poly(A) binding protein, cytoplasmic 1
chrX_+_22050546 0.46 ENST00000379374.4
PHEX
phosphate regulating endopeptidase homolog, X-linked
chr12_+_56522001 0.45 ENST00000267113.4
ENST00000541590.1
ESYT1
extended synaptotagmin-like protein 1
chr4_+_169633310 0.45 ENST00000510998.1
PALLD
palladin, cytoskeletal associated protein
chr14_+_65016620 0.44 ENST00000298705.1
PPP1R36
protein phosphatase 1, regulatory subunit 36
chr8_+_26150628 0.43 ENST00000523925.1
ENST00000315985.7
PPP2R2A
protein phosphatase 2, regulatory subunit B, alpha
chr5_-_147286065 0.43 ENST00000318315.4
ENST00000515291.1
C5orf46
chromosome 5 open reading frame 46
chr1_+_61548225 0.43 ENST00000371187.3
NFIA
nuclear factor I/A
chr12_-_22063787 0.43 ENST00000544039.1
ABCC9
ATP-binding cassette, sub-family C (CFTR/MRP), member 9
chr7_-_104909435 0.43 ENST00000357311.3
SRPK2
SRSF protein kinase 2
chr3_-_79816965 0.41 ENST00000464233.1
ROBO1
roundabout, axon guidance receptor, homolog 1 (Drosophila)
chr1_-_94586651 0.40 ENST00000535735.1
ENST00000370225.3
ABCA4
ATP-binding cassette, sub-family A (ABC1), member 4
chr5_-_138534071 0.40 ENST00000394817.2
SIL1
SIL1 nucleotide exchange factor
chr5_-_115890554 0.39 ENST00000509665.1
SEMA6A
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
chr11_-_16419067 0.39 ENST00000533411.1
SOX6
SRY (sex determining region Y)-box 6
chr2_-_214017151 0.39 ENST00000452786.1
IKZF2
IKAROS family zinc finger 2 (Helios)
chr14_+_32798462 0.39 ENST00000280979.4
AKAP6
A kinase (PRKA) anchor protein 6
chr20_+_52105495 0.39 ENST00000439873.2
AL354993.1
Cell growth-inhibiting protein 7; HCG1784586; Uncharacterized protein
chr16_+_68279256 0.39 ENST00000564827.2
ENST00000566188.1
ENST00000444212.2
ENST00000568082.1
PLA2G15
phospholipase A2, group XV
chr5_-_56778635 0.37 ENST00000423391.1
ACTBL2
actin, beta-like 2
chr4_-_57547454 0.37 ENST00000556376.2
HOPX
HOP homeobox
chr4_+_104346194 0.37 ENST00000510200.1
RP11-328K4.1
RP11-328K4.1
chr10_+_115511213 0.36 ENST00000361048.1
PLEKHS1
pleckstrin homology domain containing, family S member 1
chr22_+_39101728 0.36 ENST00000216044.5
ENST00000484657.1
GTPBP1
GTP binding protein 1
chr20_+_30697298 0.36 ENST00000398022.2
TM9SF4
transmembrane 9 superfamily protein member 4
chr5_-_145562147 0.36 ENST00000545646.1
ENST00000274562.9
ENST00000510191.1
ENST00000394434.2
LARS
leucyl-tRNA synthetase
chr1_+_117544366 0.35 ENST00000256652.4
ENST00000369470.1
CD101
CD101 molecule
chr12_+_93096759 0.34 ENST00000544406.2
C12orf74
chromosome 12 open reading frame 74
chr1_+_107683436 0.32 ENST00000370068.1
NTNG1
netrin G1
chr7_-_84122033 0.31 ENST00000424555.1
SEMA3A
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr1_-_237167718 0.31 ENST00000464121.2
MT1HL1
metallothionein 1H-like 1
chr5_+_176811431 0.31 ENST00000512593.1
ENST00000324417.5
SLC34A1
solute carrier family 34 (type II sodium/phosphate contransporter), member 1
chr8_+_28748765 0.31 ENST00000355231.5
HMBOX1
homeobox containing 1
chrX_+_55744166 0.31 ENST00000374941.4
ENST00000414239.1
RRAGB
Ras-related GTP binding B
chr5_+_53751445 0.30 ENST00000302005.1
HSPB3
heat shock 27kDa protein 3
chr14_-_73360796 0.30 ENST00000556509.1
ENST00000541685.1
ENST00000546183.1
DPF3
D4, zinc and double PHD fingers, family 3
chr1_-_227505289 0.30 ENST00000366765.3
CDC42BPA
CDC42 binding protein kinase alpha (DMPK-like)
chr10_-_116418053 0.30 ENST00000277895.5
ABLIM1
actin binding LIM protein 1

Network of associatons between targets according to the STRING database.

First level regulatory network of LMX1B_MNX1_RAX2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 3.8 GO:0060489 orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490)
1.0 8.9 GO:1900623 regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.7 2.0 GO:0070175 positive regulation of enamel mineralization(GO:0070175)
0.6 22.2 GO:0032331 negative regulation of chondrocyte differentiation(GO:0032331)
0.6 2.9 GO:0060005 vestibular reflex(GO:0060005)
0.5 2.3 GO:0042663 regulation of endodermal cell fate specification(GO:0042663)
0.4 1.7 GO:0061357 positive regulation of Wnt protein secretion(GO:0061357)
0.3 1.4 GO:1903045 neural crest cell migration involved in sympathetic nervous system development(GO:1903045)
0.3 8.0 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.3 1.2 GO:0002384 hepatic immune response(GO:0002384)
0.3 2.3 GO:1905066 positive regulation of ephrin receptor signaling pathway(GO:1901189) regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901295) positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) regulation of canonical Wnt signaling pathway involved in heart development(GO:1905066) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068)
0.3 0.8 GO:0060738 epithelial-mesenchymal signaling involved in prostate gland development(GO:0060738)
0.3 4.3 GO:0043249 erythrocyte maturation(GO:0043249)
0.3 3.3 GO:0048706 embryonic skeletal system development(GO:0048706)
0.3 0.8 GO:0002644 negative regulation of tolerance induction(GO:0002644) positive regulation of interleukin-4 biosynthetic process(GO:0045404)
0.2 0.7 GO:1903774 positive regulation of viral budding via host ESCRT complex(GO:1903774)
0.2 1.1 GO:0035513 oxidative RNA demethylation(GO:0035513) oxidative single-stranded RNA demethylation(GO:0035553)
0.2 1.4 GO:0061484 hematopoietic stem cell homeostasis(GO:0061484)
0.2 4.3 GO:0097264 self proteolysis(GO:0097264)
0.2 0.9 GO:0021827 cerebral cortex tangential migration using cell-cell interactions(GO:0021823) postnatal olfactory bulb interneuron migration(GO:0021827) chemorepulsion involved in postnatal olfactory bulb interneuron migration(GO:0021836)
0.2 2.5 GO:1904352 positive regulation of protein catabolic process in the vacuole(GO:1904352)
0.2 2.7 GO:0097475 motor neuron migration(GO:0097475)
0.2 12.0 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.1 2.0 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.1 3.3 GO:1900745 positive regulation of p38MAPK cascade(GO:1900745)
0.1 0.7 GO:0002501 peptide antigen assembly with MHC protein complex(GO:0002501)
0.1 0.4 GO:0006429 glutaminyl-tRNA aminoacylation(GO:0006425) leucyl-tRNA aminoacylation(GO:0006429)
0.1 1.4 GO:0021759 globus pallidus development(GO:0021759)
0.1 0.4 GO:0046338 phosphatidylethanolamine catabolic process(GO:0046338)
0.1 0.3 GO:0097187 dentinogenesis(GO:0097187) regulation of sodium-dependent phosphate transport(GO:2000118)
0.1 0.5 GO:0048842 positive regulation of axon extension involved in axon guidance(GO:0048842)
0.1 0.7 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
0.1 0.3 GO:0072356 chromosome passenger complex localization to kinetochore(GO:0072356)
0.1 0.4 GO:2001224 positive regulation of neuron migration(GO:2001224)
0.1 0.5 GO:1904383 response to sodium phosphate(GO:1904383)
0.1 0.2 GO:1904017 cellular response to Thyroglobulin triiodothyronine(GO:1904017)
0.1 0.2 GO:0006667 sphinganine metabolic process(GO:0006667)
0.1 0.4 GO:0035063 nuclear speck organization(GO:0035063)
0.1 1.9 GO:0051639 actin filament network formation(GO:0051639)
0.1 3.8 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.1 0.9 GO:0061734 parkin-mediated mitophagy in response to mitochondrial depolarization(GO:0061734)
0.1 1.3 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.1 1.9 GO:0071447 cellular response to hydroperoxide(GO:0071447)
0.1 0.8 GO:0061669 spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.1 1.6 GO:0071481 cellular response to X-ray(GO:0071481)
0.1 1.2 GO:0072189 ureter development(GO:0072189)
0.1 2.0 GO:0009954 proximal/distal pattern formation(GO:0009954)
0.1 1.3 GO:0007379 segment specification(GO:0007379)
0.1 0.9 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.1 6.6 GO:0016266 O-glycan processing(GO:0016266)
0.1 0.8 GO:0007258 JUN phosphorylation(GO:0007258)
0.1 0.4 GO:0060025 primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185) regulation of synaptic activity(GO:0060025)
0.1 12.5 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.1 1.4 GO:0061049 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.1 1.3 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.1 0.2 GO:0043438 acetoacetic acid metabolic process(GO:0043438)
0.1 0.4 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
0.1 1.4 GO:0003334 keratinocyte development(GO:0003334)
0.1 2.3 GO:0031954 positive regulation of protein autophosphorylation(GO:0031954)
0.1 1.8 GO:0045730 respiratory burst(GO:0045730)
0.0 0.7 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.0 1.1 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)
0.0 0.5 GO:0043950 positive regulation of cAMP-mediated signaling(GO:0043950)
0.0 2.3 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.0 0.2 GO:0072502 cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.0 0.9 GO:0086016 AV node cell action potential(GO:0086016) AV node cell to bundle of His cell signaling(GO:0086027)
0.0 0.0 GO:0021847 ventricular zone neuroblast division(GO:0021847)
0.0 0.2 GO:0006540 glutamate decarboxylation to succinate(GO:0006540)
0.0 0.5 GO:2000623 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.0 0.1 GO:0008616 queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
0.0 3.0 GO:0061001 regulation of dendritic spine morphogenesis(GO:0061001)
0.0 0.2 GO:0014722 regulation of skeletal muscle contraction by calcium ion signaling(GO:0014722) regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.0 0.7 GO:1900121 negative regulation of receptor binding(GO:1900121)
0.0 2.9 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.0 1.7 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 0.3 GO:1990253 cellular response to leucine starvation(GO:1990253)
0.0 3.1 GO:0032508 DNA duplex unwinding(GO:0032508)
0.0 1.2 GO:0051131 chaperone-mediated protein complex assembly(GO:0051131)
0.0 0.1 GO:0051799 negative regulation of hair follicle development(GO:0051799)
0.0 0.1 GO:1904899 regulation of hepatic stellate cell proliferation(GO:1904897) positive regulation of hepatic stellate cell proliferation(GO:1904899) hepatic stellate cell proliferation(GO:1990922)
0.0 0.2 GO:0021779 oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780)
0.0 0.2 GO:0009449 gamma-aminobutyric acid biosynthetic process(GO:0009449)
0.0 0.2 GO:0002933 lipid hydroxylation(GO:0002933)
0.0 0.5 GO:0006183 GTP biosynthetic process(GO:0006183)
0.0 1.4 GO:0006458 'de novo' protein folding(GO:0006458)
0.0 0.2 GO:0016078 tRNA catabolic process(GO:0016078)
0.0 0.4 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
0.0 0.4 GO:0070072 proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.0 0.7 GO:0001701 in utero embryonic development(GO:0001701)
0.0 0.7 GO:0002230 positive regulation of defense response to virus by host(GO:0002230)
0.0 0.3 GO:0030299 intestinal cholesterol absorption(GO:0030299) intestinal lipid absorption(GO:0098856)
0.0 0.3 GO:0035873 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873)
0.0 10.4 GO:0018105 peptidyl-serine phosphorylation(GO:0018105)
0.0 0.6 GO:0050860 negative regulation of T cell receptor signaling pathway(GO:0050860)
0.0 0.1 GO:0035726 common myeloid progenitor cell proliferation(GO:0035726)
0.0 0.1 GO:0044026 DNA hypermethylation(GO:0044026)
0.0 0.2 GO:0015889 cobalamin transport(GO:0015889)
0.0 0.2 GO:0021615 glossopharyngeal nerve morphogenesis(GO:0021615)
0.0 2.0 GO:0006501 C-terminal protein lipidation(GO:0006501)
0.0 0.3 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.0 0.5 GO:0045898 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.0 0.8 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 0.1 GO:0002018 renin-angiotensin regulation of aldosterone production(GO:0002018)
0.0 0.3 GO:0015825 L-serine transport(GO:0015825)
0.0 0.3 GO:0035563 positive regulation of chromatin binding(GO:0035563)
0.0 0.9 GO:1904893 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0 0.4 GO:0046039 GTP metabolic process(GO:0046039)
0.0 7.1 GO:0051056 regulation of small GTPase mediated signal transduction(GO:0051056)
0.0 1.0 GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway(GO:0030512)
0.0 2.4 GO:0030308 negative regulation of cell growth(GO:0030308)
0.0 0.6 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 8.9 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
1.0 3.8 GO:0060187 cell pole(GO:0060187)
0.6 3.4 GO:0045272 plasma membrane respiratory chain complex I(GO:0045272)
0.2 1.2 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.2 2.2 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.2 3.2 GO:0030478 actin cap(GO:0030478)
0.2 1.6 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.2 1.8 GO:0032010 phagolysosome(GO:0032010)
0.1 6.7 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.1 0.9 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.1 2.7 GO:0071565 nBAF complex(GO:0071565)
0.1 0.7 GO:0042824 MHC class I peptide loading complex(GO:0042824)
0.1 1.3 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.1 0.2 GO:0045095 keratin filament(GO:0045095)
0.1 1.9 GO:0070469 respiratory chain(GO:0070469)
0.1 1.4 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.1 0.5 GO:1990578 perinuclear endoplasmic reticulum membrane(GO:1990578)
0.1 2.6 GO:0030057 desmosome(GO:0030057)
0.1 0.4 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.1 0.3 GO:1990131 Gtr1-Gtr2 GTPase complex(GO:1990131)
0.0 0.7 GO:0001673 male germ cell nucleus(GO:0001673)
0.0 1.7 GO:0032839 dendrite cytoplasm(GO:0032839)
0.0 11.0 GO:0043197 dendritic spine(GO:0043197)
0.0 1.3 GO:0031258 lamellipodium membrane(GO:0031258)
0.0 0.7 GO:0000815 ESCRT III complex(GO:0000815)
0.0 0.8 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 2.4 GO:0002102 podosome(GO:0002102)
0.0 1.3 GO:0001533 cornified envelope(GO:0001533)
0.0 0.2 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.0 0.2 GO:0014802 terminal cisterna(GO:0014802)
0.0 0.2 GO:0045009 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.0 8.2 GO:0043209 myelin sheath(GO:0043209)
0.0 0.4 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.0 0.2 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.0 0.9 GO:0031306 intrinsic component of mitochondrial outer membrane(GO:0031306)
0.0 0.5 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 2.8 GO:0005581 collagen trimer(GO:0005581)
0.0 1.0 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.5 GO:0044232 organelle membrane contact site(GO:0044232)
0.0 0.7 GO:0005605 basal lamina(GO:0005605)
0.0 0.3 GO:0097427 microtubule bundle(GO:0097427)
0.0 1.0 GO:0005865 striated muscle thin filament(GO:0005865)
0.0 0.4 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
0.0 0.2 GO:0061202 clathrin-sculpted gamma-aminobutyric acid transport vesicle(GO:0061200) clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane(GO:0061202)
0.0 0.2 GO:0017059 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0 0.4 GO:0097381 photoreceptor disc membrane(GO:0097381)
0.0 0.2 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 3.4 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0 0.3 GO:1990023 mitotic spindle midzone(GO:1990023)
0.0 1.9 GO:0000794 condensed nuclear chromosome(GO:0000794)
0.0 2.2 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 0.8 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.1 GO:0035068 micro-ribonucleoprotein complex(GO:0035068)
0.0 31.9 GO:0005794 Golgi apparatus(GO:0005794)
0.0 0.1 GO:0097504 Gemini of coiled bodies(GO:0097504)
0.0 3.0 GO:0005730 nucleolus(GO:0005730)
0.0 0.4 GO:0000159 protein phosphatase type 2A complex(GO:0000159)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 22.2 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.4 2.4 GO:0052828 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828)
0.4 1.2 GO:0070119 ciliary neurotrophic factor binding(GO:0070119)
0.3 8.0 GO:0001608 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.2 2.3 GO:0045545 syndecan binding(GO:0045545)
0.2 1.6 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.2 1.1 GO:0035515 oxidative RNA demethylase activity(GO:0035515)
0.2 4.0 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.2 1.0 GO:0031852 mu-type opioid receptor binding(GO:0031852)
0.2 12.4 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.2 7.6 GO:0005540 hyaluronic acid binding(GO:0005540)
0.2 1.4 GO:0000285 1-phosphatidylinositol-3-phosphate 5-kinase activity(GO:0000285)
0.2 6.4 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.1 0.5 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.1 0.4 GO:0004823 glutamine-tRNA ligase activity(GO:0004819) leucine-tRNA ligase activity(GO:0004823)
0.1 0.8 GO:1990254 keratin filament binding(GO:1990254)
0.1 0.9 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.1 0.4 GO:0008281 sulfonylurea receptor activity(GO:0008281)
0.1 0.9 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.1 1.8 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.1 3.2 GO:0005523 tropomyosin binding(GO:0005523)
0.1 0.7 GO:0001849 complement component C1q binding(GO:0001849)
0.1 0.9 GO:0008046 axon guidance receptor activity(GO:0008046)
0.1 1.7 GO:0000150 recombinase activity(GO:0000150)
0.1 0.7 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.1 4.6 GO:0046875 ephrin receptor binding(GO:0046875)
0.1 1.6 GO:0030215 semaphorin receptor binding(GO:0030215)
0.1 1.6 GO:0044213 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.1 0.8 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.1 0.2 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.1 0.2 GO:0016716 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen(GO:0016716)
0.1 3.1 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.0 0.5 GO:0005168 neurotrophin TRKA receptor binding(GO:0005168)
0.0 0.4 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.0 0.3 GO:0015321 sodium-dependent phosphate transmembrane transporter activity(GO:0015321)
0.0 0.2 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.0 5.0 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 1.4 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 2.4 GO:0008094 DNA-dependent ATPase activity(GO:0008094)
0.0 0.6 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 1.1 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 0.2 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.0 0.2 GO:0033695 oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875)
0.0 1.5 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 1.0 GO:0015002 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.1 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.0 8.6 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 1.3 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.2 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.0 0.4 GO:0048156 tau protein binding(GO:0048156)
0.0 9.8 GO:0000287 magnesium ion binding(GO:0000287)
0.0 0.4 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.0 0.3 GO:0003691 double-stranded telomeric DNA binding(GO:0003691)
0.0 8.3 GO:0051015 actin filament binding(GO:0051015)
0.0 1.5 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0 0.2 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.0 0.3 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.0 0.7 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.5 GO:0008494 translation activator activity(GO:0008494)
0.0 20.7 GO:0005509 calcium ion binding(GO:0005509)
0.0 3.2 GO:0047485 protein N-terminus binding(GO:0047485)
0.0 0.4 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.4 GO:0043495 protein anchor(GO:0043495)
0.0 0.1 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.6 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.0 1.7 GO:0016491 oxidoreductase activity(GO:0016491)
0.0 7.9 GO:0005096 GTPase activator activity(GO:0005096)
0.0 0.3 GO:0015194 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0 0.8 GO:0015026 coreceptor activity(GO:0015026)
0.0 0.1 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591) thiamine pyrophosphate binding(GO:0030976)
0.0 0.3 GO:0048365 Rac GTPase binding(GO:0048365)
0.0 0.1 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 22.8 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.3 10.1 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.1 4.6 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.0 3.1 NABA COLLAGENS Genes encoding collagen proteins
0.0 2.2 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 2.3 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.0 4.0 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 2.3 PID PS1 PATHWAY Presenilin action in Notch and Wnt signaling
0.0 4.0 PID E2F PATHWAY E2F transcription factor network
0.0 2.2 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 1.9 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 6.5 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 1.7 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 1.8 PID ARF6 PATHWAY Arf6 signaling events
0.0 0.7 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 1.8 PID RAC1 PATHWAY RAC1 signaling pathway
0.0 0.8 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 0.4 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 0.8 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.9 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 0.2 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.5 PID CXCR3 PATHWAY CXCR3-mediated signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 8.9 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.2 4.0 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.2 9.8 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.1 19.4 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.1 2.6 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.1 2.4 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.1 2.2 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.1 6.6 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.1 1.2 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.1 1.4 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 0.7 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 0.5 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.0 0.9 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 0.8 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.0 1.3 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 2.5 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 1.8 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0 3.1 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.8 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 3.0 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 2.0 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 0.6 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.7 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.5 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.4 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.0 4.2 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.3 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 0.1 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.0 0.2 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 0.4 REACTOME INWARDLY RECTIFYING K CHANNELS Genes involved in Inwardly rectifying K+ channels