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SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for MAFK

Z-value: 0.57

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Transcription factors associated with MAFK

Gene Symbol Gene ID Gene Info
MAFK
ENSG00000198517.5 MAF bZIP transcription factor K

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
MAFKhg19_v2_chr7_+_1570322_1570360-0.426.7e-02Click!

Activity profile of MAFK motif

Sorted Z-values of MAFK motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr6_-_113953705 1.05 ENST00000452675.1
RP11-367G18.1
RP11-367G18.1
chr12_-_52912901 0.89 ENST00000551188.1
KRT5
keratin 5
chr10_+_118187379 0.80 ENST00000369230.3
PNLIPRP3
pancreatic lipase-related protein 3
chr1_+_156030937 0.72 ENST00000361084.5
RAB25
RAB25, member RAS oncogene family
chr17_-_39780819 0.65 ENST00000311208.8
KRT17
keratin 17
chr11_+_57365150 0.64 ENST00000457869.1
ENST00000340687.6
ENST00000378323.4
ENST00000378324.2
ENST00000403558.1
SERPING1
serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
chr6_-_47010061 0.62 ENST00000371253.2
GPR110
G protein-coupled receptor 110
chr17_-_39781054 0.59 ENST00000463128.1
KRT17
keratin 17
chr5_+_147443534 0.58 ENST00000398454.1
ENST00000359874.3
ENST00000508733.1
ENST00000256084.7
SPINK5
serine peptidase inhibitor, Kazal type 5
chr6_-_56507586 0.54 ENST00000439203.1
ENST00000518935.1
ENST00000446842.2
ENST00000370765.6
ENST00000244364.6
DST
dystonin
chr19_+_35609380 0.54 ENST00000604621.1
FXYD3
FXYD domain containing ion transport regulator 3
chr3_+_122044084 0.50 ENST00000264474.3
ENST00000479204.1
CSTA
cystatin A (stefin A)
chr6_-_47009996 0.50 ENST00000371243.2
GPR110
G protein-coupled receptor 110
chr1_+_104104379 0.50 ENST00000435302.1
AMY2B
amylase, alpha 2B (pancreatic)
chr12_-_15103621 0.48 ENST00000536592.1
ARHGDIB
Rho GDP dissociation inhibitor (GDI) beta
chr19_+_35607166 0.47 ENST00000604255.1
ENST00000346446.5
ENST00000344013.6
ENST00000603449.1
ENST00000406988.1
ENST00000605550.1
ENST00000604804.1
ENST00000605552.1
FXYD3
FXYD domain containing ion transport regulator 3
chr17_-_7167279 0.47 ENST00000571932.2
CLDN7
claudin 7
chr6_+_106988986 0.46 ENST00000457437.1
ENST00000535438.1
AIM1
absent in melanoma 1
chr1_+_87012922 0.46 ENST00000263723.5
CLCA4
chloride channel accessory 4
chr1_+_160709055 0.45 ENST00000368043.3
ENST00000368042.3
ENST00000458602.2
ENST00000458104.2
SLAMF7
SLAM family member 7
chr7_+_40174565 0.45 ENST00000309930.5
ENST00000401647.2
ENST00000335693.4
ENST00000413931.1
ENST00000416370.1
ENST00000540834.1
C7orf10
succinylCoA:glutarate-CoA transferase
chr1_+_87012753 0.44 ENST00000370563.3
CLCA4
chloride channel accessory 4
chr2_+_47596287 0.42 ENST00000263735.4
EPCAM
epithelial cell adhesion molecule
chr9_-_21975088 0.42 ENST00000304494.5
CDKN2A
cyclin-dependent kinase inhibitor 2A
chr4_-_110723134 0.40 ENST00000510800.1
ENST00000512148.1
CFI
complement factor I
chr1_+_85527987 0.40 ENST00000326813.8
ENST00000294664.6
ENST00000528899.1
WDR63
WD repeat domain 63
chr18_+_61254570 0.40 ENST00000344731.5
SERPINB13
serpin peptidase inhibitor, clade B (ovalbumin), member 13
chr6_-_28321971 0.40 ENST00000396838.2
ENST00000426434.1
ENST00000434036.1
ENST00000439628.1
ZSCAN31
zinc finger and SCAN domain containing 31
chr19_-_51529849 0.40 ENST00000600362.1
ENST00000453757.3
ENST00000601671.1
KLK11
kallikrein-related peptidase 11
chr4_-_153601136 0.39 ENST00000504064.1
ENST00000304385.3
TMEM154
transmembrane protein 154
chr18_+_61564389 0.39 ENST00000397996.2
ENST00000418725.1
SERPINB10
serpin peptidase inhibitor, clade B (ovalbumin), member 10
chr3_-_121379739 0.39 ENST00000428394.2
ENST00000314583.3
HCLS1
hematopoietic cell-specific Lyn substrate 1
chr5_-_143550241 0.38 ENST00000522203.1
YIPF5
Yip1 domain family, member 5
chr10_-_10836919 0.38 ENST00000602763.1
ENST00000415590.2
ENST00000434919.2
SFTA1P
surfactant associated 1, pseudogene
chr4_+_79475019 0.38 ENST00000508214.1
ANXA3
annexin A3
chr7_+_141490017 0.37 ENST00000247883.4
TAS2R5
taste receptor, type 2, member 5
chr18_+_61445007 0.36 ENST00000447428.1
ENST00000546027.1
SERPINB7
serpin peptidase inhibitor, clade B (ovalbumin), member 7
chr18_+_61554932 0.35 ENST00000299502.4
ENST00000457692.1
ENST00000413956.1
SERPINB2
serpin peptidase inhibitor, clade B (ovalbumin), member 2
chr14_+_94640633 0.35 ENST00000304338.3
PPP4R4
protein phosphatase 4, regulatory subunit 4
chr19_-_9811347 0.34 ENST00000585964.1
ENST00000457674.2
ENST00000590544.1
ZNF812
zinc finger protein 812
chr1_+_17516275 0.34 ENST00000412427.1
RP11-380J14.1
RP11-380J14.1
chr17_+_66511540 0.34 ENST00000588188.2
PRKAR1A
protein kinase, cAMP-dependent, regulatory, type I, alpha
chr17_+_50939459 0.33 ENST00000412360.1
AC102948.2
Uncharacterized protein
chr18_-_61329118 0.33 ENST00000332821.8
ENST00000283752.5
SERPINB3
serpin peptidase inhibitor, clade B (ovalbumin), member 3
chr3_-_151034734 0.33 ENST00000260843.4
GPR87
G protein-coupled receptor 87
chr21_+_39628655 0.33 ENST00000398925.1
ENST00000398928.1
ENST00000328656.4
ENST00000443341.1
KCNJ15
potassium inwardly-rectifying channel, subfamily J, member 15
chr11_+_34642656 0.32 ENST00000257831.3
ENST00000450654.2
EHF
ets homologous factor
chr8_-_49833978 0.32 ENST00000020945.1
SNAI2
snail family zinc finger 2
chr3_-_176914191 0.32 ENST00000437738.1
ENST00000424913.1
ENST00000443315.1
TBL1XR1
transducin (beta)-like 1 X-linked receptor 1
chr3_+_189507523 0.32 ENST00000437221.1
ENST00000392463.2
ENST00000392461.3
ENST00000449992.1
ENST00000456148.1
TP63
tumor protein p63
chr21_+_39628852 0.32 ENST00000398938.2
KCNJ15
potassium inwardly-rectifying channel, subfamily J, member 15
chr18_+_61254534 0.31 ENST00000269489.5
SERPINB13
serpin peptidase inhibitor, clade B (ovalbumin), member 13
chr3_-_93747425 0.31 ENST00000315099.2
STX19
syntaxin 19
chr12_-_91546926 0.31 ENST00000550758.1
DCN
decorin
chrX_-_80377162 0.31 ENST00000430960.1
ENST00000447319.1
HMGN5
high mobility group nucleosome binding domain 5
chr2_+_113885138 0.31 ENST00000409930.3
IL1RN
interleukin 1 receptor antagonist
chr19_-_35323762 0.31 ENST00000590963.1
CTC-523E23.4
CTC-523E23.4
chr6_-_28321909 0.31 ENST00000446222.1
ZSCAN31
zinc finger and SCAN domain containing 31
chr14_+_94640671 0.30 ENST00000328839.3
PPP4R4
protein phosphatase 4, regulatory subunit 4
chr19_-_53193731 0.30 ENST00000598536.1
ENST00000594682.2
ENST00000601257.1
ZNF83
zinc finger protein 83
chr10_+_13628921 0.30 ENST00000378572.3
PRPF18
pre-mRNA processing factor 18
chr5_-_134914673 0.30 ENST00000512158.1
CXCL14
chemokine (C-X-C motif) ligand 14
chr4_-_90756769 0.29 ENST00000345009.4
ENST00000505199.1
ENST00000502987.1
SNCA
synuclein, alpha (non A4 component of amyloid precursor)
chr6_-_75828774 0.28 ENST00000493109.2
COL12A1
collagen, type XII, alpha 1
chr11_-_8816375 0.28 ENST00000530580.1
ST5
suppression of tumorigenicity 5
chr17_+_30089454 0.27 ENST00000577970.1
RP11-805L22.3
RP11-805L22.3
chr7_-_20256965 0.27 ENST00000400331.5
ENST00000332878.4
MACC1
metastasis associated in colon cancer 1
chr1_+_160709029 0.27 ENST00000444090.2
ENST00000441662.2
SLAMF7
SLAM family member 7
chr7_-_98805129 0.27 ENST00000327442.6
KPNA7
karyopherin alpha 7 (importin alpha 8)
chr2_-_214013353 0.27 ENST00000451136.2
ENST00000421754.2
ENST00000374327.4
ENST00000413091.3
IKZF2
IKAROS family zinc finger 2 (Helios)
chr3_-_111314230 0.27 ENST00000317012.4
ZBED2
zinc finger, BED-type containing 2
chr6_-_32784687 0.27 ENST00000447394.1
ENST00000438763.2
HLA-DOB
major histocompatibility complex, class II, DO beta
chr2_+_169926047 0.27 ENST00000428522.1
ENST00000450153.1
ENST00000421653.1
DHRS9
dehydrogenase/reductase (SDR family) member 9
chr1_+_95975672 0.27 ENST00000440116.2
ENST00000456933.1
RP11-286B14.1
RP11-286B14.1
chr19_-_46916805 0.27 ENST00000307522.3
CCDC8
coiled-coil domain containing 8
chr19_-_58459039 0.26 ENST00000282308.3
ENST00000598928.1
ZNF256
zinc finger protein 256
chrX_-_80377118 0.26 ENST00000373250.3
HMGN5
high mobility group nucleosome binding domain 5
chr1_+_158979680 0.26 ENST00000368131.4
ENST00000340979.6
IFI16
interferon, gamma-inducible protein 16
chr3_+_45730829 0.26 ENST00000438671.1
SACM1L
SAC1 suppressor of actin mutations 1-like (yeast)
chr4_-_90757364 0.25 ENST00000508895.1
SNCA
synuclein, alpha (non A4 component of amyloid precursor)
chr4_-_74486217 0.25 ENST00000335049.5
ENST00000307439.5
RASSF6
Ras association (RalGDS/AF-6) domain family member 6
chr8_-_101718991 0.25 ENST00000517990.1
PABPC1
poly(A) binding protein, cytoplasmic 1
chr3_-_105588231 0.25 ENST00000545639.1
ENST00000394027.3
ENST00000438603.1
ENST00000447441.1
ENST00000443752.1
CBLB
Cbl proto-oncogene B, E3 ubiquitin protein ligase
chr12_+_48876275 0.25 ENST00000314014.2
C12orf54
chromosome 12 open reading frame 54
chr2_+_90458201 0.25 ENST00000603238.1
CH17-132F21.1
Uncharacterized protein
chr1_+_158979792 0.25 ENST00000359709.3
ENST00000430894.2
IFI16
interferon, gamma-inducible protein 16
chr5_-_133510456 0.24 ENST00000520417.1
SKP1
S-phase kinase-associated protein 1
chr11_-_59633951 0.24 ENST00000257264.3
TCN1
transcobalamin I (vitamin B12 binding protein, R binder family)
chr1_-_153113927 0.24 ENST00000368752.4
SPRR2B
small proline-rich protein 2B
chr3_-_196910477 0.24 ENST00000447466.1
DLG1
discs, large homolog 1 (Drosophila)
chr7_-_17598506 0.24 ENST00000451792.1
AC017060.1
AC017060.1
chr6_-_28973037 0.24 ENST00000377179.3
ZNF311
zinc finger protein 311
chr5_-_74326724 0.24 ENST00000322348.4
GCNT4
glucosaminyl (N-acetyl) transferase 4, core 2
chr11_-_104972158 0.24 ENST00000598974.1
ENST00000593315.1
ENST00000594519.1
ENST00000415981.2
ENST00000525374.1
ENST00000375707.1
CASP1
CARD16
CARD17
caspase 1, apoptosis-related cysteine peptidase
caspase recruitment domain family, member 16
caspase recruitment domain family, member 17
chr11_-_102826434 0.24 ENST00000340273.4
ENST00000260302.3
MMP13
matrix metallopeptidase 13 (collagenase 3)
chr4_+_119200215 0.24 ENST00000602573.1
SNHG8
small nucleolar RNA host gene 8 (non-protein coding)
chr6_+_45296391 0.23 ENST00000371436.6
ENST00000576263.1
RUNX2
runt-related transcription factor 2
chr1_+_158978768 0.23 ENST00000447473.2
IFI16
interferon, gamma-inducible protein 16
chr12_+_51318513 0.23 ENST00000332160.4
METTL7A
methyltransferase like 7A
chr16_+_82068830 0.23 ENST00000199936.4
HSD17B2
hydroxysteroid (17-beta) dehydrogenase 2
chr18_+_61442629 0.22 ENST00000398019.2
ENST00000540675.1
SERPINB7
serpin peptidase inhibitor, clade B (ovalbumin), member 7
chr11_-_58345569 0.22 ENST00000528954.1
ENST00000528489.1
LPXN
leupaxin
chr11_+_34654011 0.22 ENST00000531794.1
EHF
ets homologous factor
chr1_+_209859510 0.22 ENST00000367028.2
ENST00000261465.1
HSD11B1
hydroxysteroid (11-beta) dehydrogenase 1
chr1_-_161046266 0.21 ENST00000453926.2
PVRL4
poliovirus receptor-related 4
chr1_-_153013588 0.21 ENST00000360379.3
SPRR2D
small proline-rich protein 2D
chr2_+_237476419 0.21 ENST00000447924.1
ACKR3
atypical chemokine receptor 3
chr18_-_32870148 0.21 ENST00000589178.1
ENST00000333206.5
ENST00000592278.1
ENST00000592211.1
ENST00000420878.3
ENST00000383091.2
ENST00000586922.2
ZSCAN30
RP11-158H5.7
zinc finger and SCAN domain containing 30
RP11-158H5.7
chr3_+_182983126 0.21 ENST00000481531.1
B3GNT5
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5
chr12_+_75784850 0.21 ENST00000550916.1
ENST00000435775.1
ENST00000378689.2
ENST00000378692.3
ENST00000320460.4
ENST00000547164.1
GLIPR1L2
GLI pathogenesis-related 1 like 2
chr17_+_66521936 0.21 ENST00000592800.1
PRKAR1A
protein kinase, cAMP-dependent, regulatory, type I, alpha
chr10_+_47746929 0.21 ENST00000340243.6
ENST00000374277.5
ENST00000449464.2
ENST00000538825.1
ENST00000335083.5
ANXA8L2
AL603965.1
annexin A8-like 2
Protein LOC100996760
chr2_-_216240386 0.21 ENST00000438981.1
FN1
fibronectin 1
chr19_-_9649253 0.21 ENST00000593003.1
ZNF426
zinc finger protein 426
chr21_-_30365136 0.21 ENST00000361371.5
ENST00000389194.2
ENST00000389195.2
LTN1
listerin E3 ubiquitin protein ligase 1
chr3_+_101818088 0.21 ENST00000491959.1
ZPLD1
zona pellucida-like domain containing 1
chr5_-_2751762 0.20 ENST00000302057.5
ENST00000382611.6
IRX2
iroquois homeobox 2
chr6_-_30640761 0.20 ENST00000415603.1
DHX16
DEAH (Asp-Glu-Ala-His) box polypeptide 16
chrX_+_135614293 0.20 ENST00000370634.3
VGLL1
vestigial like 1 (Drosophila)
chr13_-_36920872 0.20 ENST00000451493.1
SPG20
spastic paraplegia 20 (Troyer syndrome)
chr10_+_116697946 0.20 ENST00000298746.3
TRUB1
TruB pseudouridine (psi) synthase family member 1
chr6_-_28321827 0.20 ENST00000444081.1
ZSCAN31
zinc finger and SCAN domain containing 31
chr20_+_32951070 0.20 ENST00000535650.1
ENST00000262650.6
ITCH
itchy E3 ubiquitin protein ligase
chr10_+_90750493 0.20 ENST00000357339.2
ENST00000355279.2
FAS
Fas cell surface death receptor
chr18_+_21693306 0.20 ENST00000540918.2
TTC39C
tetratricopeptide repeat domain 39C
chr1_+_158979686 0.20 ENST00000368132.3
ENST00000295809.7
IFI16
interferon, gamma-inducible protein 16
chr18_-_68004529 0.20 ENST00000578633.1
RP11-484N16.1
RP11-484N16.1
chr1_+_87170277 0.20 ENST00000535010.1
SH3GLB1
SH3-domain GRB2-like endophilin B1
chr4_-_4544061 0.20 ENST00000507908.1
STX18
syntaxin 18
chr12_+_69202795 0.20 ENST00000539479.1
ENST00000393415.3
ENST00000523991.1
ENST00000543323.1
ENST00000393416.2
MDM2
MDM2 oncogene, E3 ubiquitin protein ligase
chr6_+_36097992 0.20 ENST00000211287.4
MAPK13
mitogen-activated protein kinase 13
chr4_-_110723335 0.19 ENST00000394634.2
CFI
complement factor I
chr10_+_24497704 0.19 ENST00000376456.4
ENST00000458595.1
KIAA1217
KIAA1217
chr8_+_125860939 0.19 ENST00000525292.1
ENST00000528090.1
LINC00964
long intergenic non-protein coding RNA 964
chr2_+_89952792 0.19 ENST00000390265.2
IGKV1D-33
immunoglobulin kappa variable 1D-33
chr13_+_73629107 0.19 ENST00000539231.1
KLF5
Kruppel-like factor 5 (intestinal)
chr2_-_214016314 0.19 ENST00000434687.1
ENST00000374319.4
IKZF2
IKAROS family zinc finger 2 (Helios)
chr12_-_46384334 0.19 ENST00000369367.3
ENST00000266589.6
ENST00000395453.2
ENST00000395454.2
SCAF11
SR-related CTD-associated factor 11
chr1_-_111970353 0.19 ENST00000369732.3
OVGP1
oviductal glycoprotein 1, 120kDa
chr15_-_41047421 0.19 ENST00000560460.1
ENST00000338376.3
ENST00000560905.1
RMDN3
regulator of microtubule dynamics 3
chr10_+_47894572 0.19 ENST00000355876.5
FAM21B
family with sequence similarity 21, member B
chr10_+_13628933 0.19 ENST00000417658.1
ENST00000320054.4
PRPF18
pre-mRNA processing factor 18
chr12_-_88535747 0.19 ENST00000309041.7
CEP290
centrosomal protein 290kDa
chr3_-_176914238 0.18 ENST00000430069.1
ENST00000428970.1
TBL1XR1
transducin (beta)-like 1 X-linked receptor 1
chr4_-_74486109 0.18 ENST00000395777.2
RASSF6
Ras association (RalGDS/AF-6) domain family member 6
chr3_+_44771088 0.18 ENST00000396048.2
ZNF501
zinc finger protein 501
chr8_+_13424352 0.18 ENST00000297324.4
C8orf48
chromosome 8 open reading frame 48
chr3_-_74570291 0.18 ENST00000263665.6
CNTN3
contactin 3 (plasmacytoma associated)
chr5_-_180287663 0.18 ENST00000509066.1
ENST00000504225.1
ZFP62
ZFP62 zinc finger protein
chr4_-_143227088 0.18 ENST00000511838.1
INPP4B
inositol polyphosphate-4-phosphatase, type II, 105kDa
chr1_-_109618566 0.18 ENST00000338366.5
TAF13
TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa
chr1_+_160709076 0.18 ENST00000359331.4
ENST00000495334.1
SLAMF7
SLAM family member 7
chr10_+_180643 0.18 ENST00000509513.2
ENST00000397959.3
ZMYND11
zinc finger, MYND-type containing 11
chr3_+_111717511 0.18 ENST00000478951.1
ENST00000393917.2
TAGLN3
transgelin 3
chr5_+_148960931 0.18 ENST00000333677.6
ARHGEF37
Rho guanine nucleotide exchange factor (GEF) 37
chr4_-_74486347 0.18 ENST00000342081.3
RASSF6
Ras association (RalGDS/AF-6) domain family member 6
chr14_+_85994943 0.18 ENST00000553678.1
RP11-497E19.2
Uncharacterized protein
chr17_+_66511224 0.18 ENST00000588178.1
PRKAR1A
protein kinase, cAMP-dependent, regulatory, type I, alpha
chrX_-_41449204 0.18 ENST00000378179.3
CASK
calcium/calmodulin-dependent serine protein kinase (MAGUK family)
chr15_+_74218787 0.18 ENST00000261921.7
LOXL1
lysyl oxidase-like 1
chr6_-_80247140 0.18 ENST00000392959.1
ENST00000467898.3
LCA5
Leber congenital amaurosis 5
chr11_-_134123142 0.18 ENST00000392595.2
ENST00000341541.3
ENST00000352327.5
ENST00000392594.3
THYN1
thymocyte nuclear protein 1
chr1_+_111682058 0.18 ENST00000545121.1
CEPT1
choline/ethanolamine phosphotransferase 1
chr1_+_81771806 0.18 ENST00000370721.1
ENST00000370727.1
ENST00000370725.1
ENST00000370723.1
ENST00000370728.1
ENST00000370730.1
LPHN2
latrophilin 2
chr1_+_144215387 0.18 ENST00000421555.2
NBPF8
neuroblastoma breakpoint family, member 8
chr1_+_171454639 0.18 ENST00000392078.3
ENST00000426496.2
PRRC2C
proline-rich coiled-coil 2C
chr19_-_9649303 0.18 ENST00000253115.2
ZNF426
zinc finger protein 426
chr15_-_41694640 0.17 ENST00000558719.1
ENST00000260361.4
ENST00000560978.1
NDUFAF1
NADH dehydrogenase (ubiquinone) complex I, assembly factor 1
chr11_-_125773085 0.17 ENST00000227474.3
ENST00000534158.1
ENST00000529801.1
PUS3
pseudouridylate synthase 3
chr19_-_36001113 0.17 ENST00000434389.1
DMKN
dermokine
chr4_-_110723194 0.17 ENST00000394635.3
CFI
complement factor I
chr3_+_43732362 0.17 ENST00000458276.2
ABHD5
abhydrolase domain containing 5
chr4_+_26324474 0.17 ENST00000514675.1
RBPJ
recombination signal binding protein for immunoglobulin kappa J region
chr8_-_42358742 0.17 ENST00000517366.1
SLC20A2
solute carrier family 20 (phosphate transporter), member 2
chr5_-_74062930 0.17 ENST00000509430.1
ENST00000345239.2
ENST00000427854.2
ENST00000506778.1
GFM2
G elongation factor, mitochondrial 2
chrX_+_18443703 0.17 ENST00000379996.3
CDKL5
cyclin-dependent kinase-like 5
chr10_-_90751038 0.17 ENST00000458159.1
ENST00000415557.1
ENST00000458208.1
ACTA2
actin, alpha 2, smooth muscle, aorta
chr13_+_103451548 0.17 ENST00000419638.1
BIVM
basic, immunoglobulin-like variable motif containing
chr3_-_171489085 0.17 ENST00000418087.1
PLD1
phospholipase D1, phosphatidylcholine-specific
chr3_+_142720366 0.17 ENST00000493782.1
ENST00000397933.2
ENST00000473835.2
ENST00000493598.2
U2SURP
U2 snRNP-associated SURP domain containing
chr7_-_143454789 0.17 ENST00000470691.2
CTAGE6
CTAGE family, member 6
chr10_-_27444143 0.17 ENST00000477432.1
YME1L1
YME1-like 1 ATPase
chr11_-_102668879 0.17 ENST00000315274.6
MMP1
matrix metallopeptidase 1 (interstitial collagenase)
chr12_-_42719885 0.17 ENST00000552673.1
ENST00000266529.3
ENST00000552235.1
ZCRB1
zinc finger CCHC-type and RNA binding motif 1
chr8_+_123875624 0.17 ENST00000534247.1
ZHX2
zinc fingers and homeoboxes 2
chr3_+_9944492 0.17 ENST00000383814.3
ENST00000454190.2
ENST00000454992.1
IL17RE
interleukin 17 receptor E
chr6_+_45296048 0.17 ENST00000465038.2
ENST00000352853.5
ENST00000541979.1
ENST00000371438.1
RUNX2
runt-related transcription factor 2
chr1_+_75198871 0.17 ENST00000479111.1
TYW3
tRNA-yW synthesizing protein 3 homolog (S. cerevisiae)
chr5_+_140079919 0.16 ENST00000274712.3
ZMAT2
zinc finger, matrin-type 2
chr12_+_56435637 0.16 ENST00000356464.5
ENST00000552361.1
RPS26
ribosomal protein S26
chr12_-_122879969 0.16 ENST00000540304.1
CLIP1
CAP-GLY domain containing linker protein 1
chr18_+_20513278 0.16 ENST00000327155.5
RBBP8
retinoblastoma binding protein 8
chr6_-_90529418 0.16 ENST00000439638.1
ENST00000369393.3
ENST00000428876.1
MDN1
MDN1, midasin homolog (yeast)
chr8_+_96146168 0.16 ENST00000519516.1
PLEKHF2
pleckstrin homology domain containing, family F (with FYVE domain) member 2
chr10_+_5488564 0.16 ENST00000449083.1
ENST00000380359.3
NET1
neuroepithelial cell transforming 1
chr21_+_40181520 0.16 ENST00000456966.1
ETS2
v-ets avian erythroblastosis virus E26 oncogene homolog 2
chr8_+_30013813 0.16 ENST00000221114.3
DCTN6
dynactin 6
chr5_+_66300464 0.16 ENST00000436277.1
MAST4
microtubule associated serine/threonine kinase family member 4
chr4_-_85654615 0.16 ENST00000514711.1
WDFY3
WD repeat and FYVE domain containing 3
chr18_-_21891460 0.16 ENST00000357041.4
OSBPL1A
oxysterol binding protein-like 1A

Network of associatons between targets according to the STRING database.

First level regulatory network of MAFK

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:1902173 negative regulation of keratinocyte apoptotic process(GO:1902173)
0.2 0.5 GO:0071048 nuclear mRNA surveillance of spliceosomal pre-mRNA splicing(GO:0071030) nuclear retention of unspliced pre-mRNA at the site of transcription(GO:0071048)
0.1 0.6 GO:0090362 positive regulation of platelet-derived growth factor production(GO:0090362)
0.1 0.5 GO:0051945 negative regulation of dopamine uptake involved in synaptic transmission(GO:0051585) norepinephrine uptake(GO:0051620) regulation of norepinephrine uptake(GO:0051621) negative regulation of norepinephrine uptake(GO:0051622) negative regulation of catecholamine uptake involved in synaptic transmission(GO:0051945) regulation of glutathione peroxidase activity(GO:1903282) positive regulation of glutathione peroxidase activity(GO:1903284) positive regulation of hydrogen peroxide catabolic process(GO:1903285) positive regulation of peroxidase activity(GO:2000470)
0.1 0.3 GO:0070563 negative regulation of vitamin D receptor signaling pathway(GO:0070563)
0.1 0.3 GO:0071301 cellular response to vitamin B1(GO:0071301) response to formaldehyde(GO:1904404)
0.1 0.8 GO:1900425 negative regulation of defense response to bacterium(GO:1900425)
0.1 0.3 GO:0002581 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581)
0.1 0.4 GO:1903778 protein localization to vacuolar membrane(GO:1903778)
0.1 0.3 GO:0035425 autocrine signaling(GO:0035425)
0.1 0.2 GO:0002121 inter-male aggressive behavior(GO:0002121)
0.1 0.3 GO:0007499 ectoderm and mesoderm interaction(GO:0007499)
0.1 0.2 GO:1904237 regulation of substrate-dependent cell migration, cell attachment to substrate(GO:1904235) positive regulation of substrate-dependent cell migration, cell attachment to substrate(GO:1904237)
0.1 0.5 GO:0071461 cellular response to redox state(GO:0071461)
0.1 0.4 GO:2000048 negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.1 0.3 GO:0035519 protein K29-linked ubiquitination(GO:0035519)
0.1 0.2 GO:0050717 positive regulation of interleukin-1 alpha secretion(GO:0050717)
0.1 0.1 GO:0032227 negative regulation of synaptic transmission, dopaminergic(GO:0032227)
0.1 0.4 GO:1990481 mRNA pseudouridine synthesis(GO:1990481)
0.1 0.2 GO:0006711 estrogen catabolic process(GO:0006711)
0.1 0.5 GO:2000660 negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
0.1 0.2 GO:0072086 specification of loop of Henle identity(GO:0072086) pattern specification involved in metanephros development(GO:0072268)
0.1 0.2 GO:0048698 negative regulation of collateral sprouting in absence of injury(GO:0048698)
0.0 0.3 GO:0097527 necroptotic signaling pathway(GO:0097527)
0.0 0.5 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.0 0.1 GO:0048003 synaptic vesicle recycling via endosome(GO:0036466) antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003) antigen processing and presentation, exogenous lipid antigen via MHC class Ib(GO:0048007)
0.0 0.2 GO:2000360 negative regulation of binding of sperm to zona pellucida(GO:2000360)
0.0 0.1 GO:0007113 endomitotic cell cycle(GO:0007113)
0.0 0.3 GO:0036111 very long-chain fatty-acyl-CoA metabolic process(GO:0036111)
0.0 1.3 GO:0051798 positive regulation of hair follicle development(GO:0051798)
0.0 0.2 GO:0018277 protein deamination(GO:0018277)
0.0 0.3 GO:2000503 positive regulation of natural killer cell chemotaxis(GO:2000503)
0.0 0.0 GO:0050720 interleukin-1 beta biosynthetic process(GO:0050720)
0.0 0.2 GO:0071684 blastocyst hatching(GO:0001835) hatching(GO:0035188) organism emergence from protective structure(GO:0071684)
0.0 0.3 GO:1903575 cornified envelope assembly(GO:1903575)
0.0 0.1 GO:0031247 actin rod assembly(GO:0031247)
0.0 0.3 GO:1901297 positive regulation of ephrin receptor signaling pathway(GO:1901189) positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068)
0.0 0.1 GO:0006043 glucosamine catabolic process(GO:0006043)
0.0 0.7 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.0 0.4 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.0 0.3 GO:0051697 protein delipidation(GO:0051697)
0.0 0.1 GO:0018352 protein-pyridoxal-5-phosphate linkage(GO:0018352)
0.0 0.4 GO:0035986 senescence-associated heterochromatin focus assembly(GO:0035986)
0.0 0.5 GO:0060613 fat pad development(GO:0060613)
0.0 0.2 GO:0090158 endoplasmic reticulum membrane organization(GO:0090158)
0.0 0.7 GO:0031268 pseudopodium organization(GO:0031268)
0.0 0.4 GO:0002051 osteoblast fate commitment(GO:0002051)
0.0 0.1 GO:2001226 negative regulation of chloride transport(GO:2001226)
0.0 0.1 GO:0002101 tRNA wobble cytosine modification(GO:0002101)
0.0 0.1 GO:0070681 glutaminyl-tRNAGln biosynthesis via transamidation(GO:0070681)
0.0 0.1 GO:1903060 regulation of N-terminal protein palmitoylation(GO:0060254) negative regulation of N-terminal protein palmitoylation(GO:0060262) negative regulation of protein lipidation(GO:1903060)
0.0 0.1 GO:0042270 protection from natural killer cell mediated cytotoxicity(GO:0042270)
0.0 0.5 GO:0008090 retrograde axonal transport(GO:0008090)
0.0 0.2 GO:0090131 mesenchyme migration(GO:0090131)
0.0 0.1 GO:1903979 negative regulation of microglial cell activation(GO:1903979)
0.0 0.2 GO:0007161 calcium-independent cell-matrix adhesion(GO:0007161)
0.0 0.1 GO:0032827 negative regulation of natural killer cell differentiation(GO:0032824) negative regulation of natural killer cell differentiation involved in immune response(GO:0032827) positive regulation of cytolysis in other organism(GO:0051714)
0.0 0.1 GO:0060151 peroxisome localization(GO:0060151) microtubule-based peroxisome localization(GO:0060152)
0.0 0.1 GO:0006435 threonyl-tRNA aminoacylation(GO:0006435)
0.0 0.1 GO:1902232 regulation of positive thymic T cell selection(GO:1902232)
0.0 0.2 GO:0018343 protein farnesylation(GO:0018343)
0.0 0.1 GO:0010430 fatty acid omega-oxidation(GO:0010430)
0.0 0.1 GO:0031455 glycine betaine biosynthetic process from choline(GO:0019285) glycine betaine metabolic process(GO:0031455) glycine betaine biosynthetic process(GO:0031456)
0.0 0.2 GO:0001712 ectodermal cell fate commitment(GO:0001712)
0.0 0.4 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.0 0.1 GO:1902544 regulation of DNA N-glycosylase activity(GO:1902544)
0.0 0.4 GO:0060628 regulation of ER to Golgi vesicle-mediated transport(GO:0060628)
0.0 0.2 GO:0010265 SCF complex assembly(GO:0010265)
0.0 0.1 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.0 0.3 GO:2000622 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.0 0.3 GO:0042904 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.0 0.1 GO:0030451 regulation of complement activation, alternative pathway(GO:0030451) negative regulation of complement activation, alternative pathway(GO:0045957)
0.0 0.2 GO:1903764 regulation of potassium ion export across plasma membrane(GO:1903764)
0.0 0.1 GO:0010637 negative regulation of mitochondrial fusion(GO:0010637)
0.0 0.9 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.1 GO:0090611 ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway(GO:0090611)
0.0 0.3 GO:1901409 positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.0 0.2 GO:0044861 protein transport into plasma membrane raft(GO:0044861)
0.0 0.1 GO:0002933 lipid hydroxylation(GO:0002933)
0.0 0.6 GO:0032515 negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.0 0.1 GO:0060621 negative regulation of cholesterol import(GO:0060621) negative regulation of sterol import(GO:2000910)
0.0 0.4 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.0 0.1 GO:0016999 antibiotic metabolic process(GO:0016999)
0.0 0.2 GO:0060161 positive regulation of dopamine receptor signaling pathway(GO:0060161)
0.0 0.1 GO:0002528 regulation of vascular permeability involved in acute inflammatory response(GO:0002528)
0.0 0.2 GO:0050859 negative regulation of B cell receptor signaling pathway(GO:0050859)
0.0 0.1 GO:2000538 regulation of cGMP-mediated signaling(GO:0010752) regulation of B cell chemotaxis(GO:2000537) positive regulation of B cell chemotaxis(GO:2000538)
0.0 0.1 GO:0033693 neurofilament bundle assembly(GO:0033693)
0.0 0.1 GO:0035621 ER to Golgi ceramide transport(GO:0035621)
0.0 0.3 GO:0030916 otic vesicle formation(GO:0030916)
0.0 0.1 GO:0002763 positive regulation of myeloid leukocyte differentiation(GO:0002763)
0.0 0.1 GO:0046586 regulation of calcium-dependent cell-cell adhesion(GO:0046586)
0.0 1.6 GO:0018149 peptide cross-linking(GO:0018149)
0.0 0.1 GO:0016094 polyprenol biosynthetic process(GO:0016094)
0.0 0.2 GO:0046952 ketone body catabolic process(GO:0046952)
0.0 0.1 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
0.0 0.1 GO:1903031 regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033)
0.0 0.1 GO:0051562 negative regulation of mitochondrial calcium ion concentration(GO:0051562)
0.0 0.1 GO:0044805 late nucleophagy(GO:0044805)
0.0 0.1 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.0 0.1 GO:1904381 Golgi apparatus mannose trimming(GO:1904381)
0.0 0.2 GO:1901098 positive regulation of autophagosome maturation(GO:1901098)
0.0 0.1 GO:0045824 negative regulation of innate immune response(GO:0045824)
0.0 0.1 GO:1904274 tricellular tight junction assembly(GO:1904274)
0.0 0.1 GO:0090234 regulation of kinetochore assembly(GO:0090234)
0.0 0.2 GO:0097396 response to interleukin-17(GO:0097396) cellular response to interleukin-17(GO:0097398)
0.0 0.1 GO:0001971 negative regulation of activation of membrane attack complex(GO:0001971)
0.0 0.1 GO:1990168 protein K33-linked deubiquitination(GO:1990168)
0.0 0.1 GO:0035552 oxidative single-stranded DNA demethylation(GO:0035552)
0.0 0.1 GO:0014835 myoblast differentiation involved in skeletal muscle regeneration(GO:0014835)
0.0 0.1 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.0 0.1 GO:0045080 positive regulation of chemokine biosynthetic process(GO:0045080)
0.0 0.1 GO:0039534 negative regulation of MDA-5 signaling pathway(GO:0039534)
0.0 0.3 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.0 0.1 GO:0042986 positive regulation of amyloid precursor protein biosynthetic process(GO:0042986)
0.0 0.1 GO:0080009 mRNA methylation(GO:0080009)
0.0 0.1 GO:0034476 U1 snRNA 3'-end processing(GO:0034473) U5 snRNA 3'-end processing(GO:0034476)
0.0 0.1 GO:0061084 regulation of protein refolding(GO:0061083) negative regulation of protein refolding(GO:0061084)
0.0 0.1 GO:0071874 cellular response to norepinephrine stimulus(GO:0071874)
0.0 0.1 GO:0032377 regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
0.0 0.0 GO:0044828 negative regulation by host of viral genome replication(GO:0044828)
0.0 0.1 GO:0033123 positive regulation of cyclic nucleotide catabolic process(GO:0030807) positive regulation of cAMP catabolic process(GO:0030822) positive regulation of purine nucleotide catabolic process(GO:0033123)
0.0 0.1 GO:0015722 canalicular bile acid transport(GO:0015722)
0.0 0.2 GO:0060681 branch elongation involved in ureteric bud branching(GO:0060681)
0.0 0.6 GO:0071157 negative regulation of cell cycle arrest(GO:0071157)
0.0 0.5 GO:0007635 chemosensory behavior(GO:0007635)
0.0 0.1 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.0 0.1 GO:0036228 protein targeting to nuclear inner membrane(GO:0036228)
0.0 0.2 GO:0034378 chylomicron assembly(GO:0034378)
0.0 0.0 GO:0000712 resolution of meiotic recombination intermediates(GO:0000712)
0.0 0.2 GO:0051451 myoblast migration(GO:0051451)
0.0 0.2 GO:0006657 CDP-choline pathway(GO:0006657)
0.0 0.0 GO:0042214 terpene metabolic process(GO:0042214)
0.0 0.1 GO:0070236 negative regulation of activation-induced cell death of T cells(GO:0070236)
0.0 0.2 GO:1902455 negative regulation of stem cell population maintenance(GO:1902455)
0.0 0.1 GO:0001692 histamine metabolic process(GO:0001692)
0.0 0.0 GO:0006990 positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response(GO:0006990)
0.0 0.1 GO:0072369 regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter(GO:0072369)
0.0 0.5 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0 0.1 GO:0034351 regulation of glial cell apoptotic process(GO:0034350) negative regulation of glial cell apoptotic process(GO:0034351)
0.0 0.1 GO:0010166 wax biosynthetic process(GO:0010025) wax metabolic process(GO:0010166)
0.0 0.0 GO:0009441 glycolate metabolic process(GO:0009441)
0.0 0.3 GO:0099500 synaptic vesicle fusion to presynaptic active zone membrane(GO:0031629) vesicle fusion to plasma membrane(GO:0099500)
0.0 0.1 GO:2000825 positive regulation of androgen receptor activity(GO:2000825)
0.0 0.2 GO:0045329 amino-acid betaine biosynthetic process(GO:0006578) carnitine biosynthetic process(GO:0045329)
0.0 0.0 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.0 0.0 GO:0061762 CAMKK-AMPK signaling cascade(GO:0061762)
0.0 0.1 GO:0061055 myotome development(GO:0061055)
0.0 0.1 GO:0002415 immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor(GO:0002415)
0.0 0.1 GO:0030643 cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.0 0.1 GO:0090487 toxin catabolic process(GO:0009407) secondary metabolite catabolic process(GO:0090487)
0.0 0.1 GO:0071475 cellular hyperosmotic salinity response(GO:0071475)
0.0 0.1 GO:1901727 positive regulation of histone deacetylase activity(GO:1901727)
0.0 0.9 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.0 0.1 GO:0070537 histone H2A K63-linked deubiquitination(GO:0070537)
0.0 0.1 GO:0045198 establishment of epithelial cell apical/basal polarity(GO:0045198)
0.0 0.2 GO:0035973 aggrephagy(GO:0035973)
0.0 0.0 GO:0021912 regulation of transcription from RNA polymerase II promoter involved in spinal cord motor neuron fate specification(GO:0021912)
0.0 0.6 GO:0010107 potassium ion import(GO:0010107)
0.0 0.2 GO:0032790 ribosome disassembly(GO:0032790)
0.0 0.1 GO:0060449 bud elongation involved in lung branching(GO:0060449)
0.0 0.1 GO:2000270 negative regulation of fibroblast apoptotic process(GO:2000270)
0.0 0.0 GO:0001951 intestinal D-glucose absorption(GO:0001951)
0.0 0.2 GO:0042354 fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355)
0.0 0.1 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
0.0 0.2 GO:1903054 negative regulation of extracellular matrix organization(GO:1903054)
0.0 0.1 GO:0036155 acylglycerol acyl-chain remodeling(GO:0036155)
0.0 0.0 GO:0034402 recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex(GO:0034402)
0.0 1.2 GO:0006958 complement activation, classical pathway(GO:0006958)
0.0 0.0 GO:0060585 detection of peptidoglycan(GO:0032499) activation of MAPK activity involved in innate immune response(GO:0035419) regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585) negative regulation of macrophage apoptotic process(GO:2000110)
0.0 0.1 GO:0042670 retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
0.0 0.2 GO:0015074 DNA integration(GO:0015074)
0.0 0.3 GO:0071447 cellular response to hydroperoxide(GO:0071447)
0.0 0.1 GO:0060219 camera-type eye photoreceptor cell differentiation(GO:0060219)
0.0 0.3 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.0 0.1 GO:0006740 NADPH regeneration(GO:0006740)
0.0 0.2 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839)
0.0 0.3 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.0 0.0 GO:1904815 negative regulation of protein localization to chromosome, telomeric region(GO:1904815)
0.0 0.3 GO:0051639 actin filament network formation(GO:0051639)
0.0 0.1 GO:0046826 negative regulation of protein export from nucleus(GO:0046826)
0.0 0.2 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.0 0.0 GO:0098884 postsynaptic neurotransmitter receptor internalization(GO:0098884)
0.0 0.1 GO:0060174 limb bud formation(GO:0060174)
0.0 0.1 GO:0006776 vitamin A metabolic process(GO:0006776) positive regulation of skeletal muscle tissue regeneration(GO:0043415)
0.0 0.0 GO:0021943 formation of radial glial scaffolds(GO:0021943)
0.0 1.8 GO:1902476 chloride transmembrane transport(GO:1902476)
0.0 0.2 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.0 0.1 GO:0035720 intraciliary anterograde transport(GO:0035720)
0.0 0.0 GO:0019482 beta-alanine metabolic process(GO:0019482)
0.0 0.2 GO:0070914 UV-damage excision repair(GO:0070914)
0.0 0.2 GO:0003417 growth plate cartilage development(GO:0003417)
0.0 0.0 GO:0043396 corticotropin-releasing hormone secretion(GO:0043396) regulation of corticotropin-releasing hormone secretion(GO:0043397) positive regulation of corticotropin-releasing hormone secretion(GO:0051466)
0.0 0.1 GO:0000710 meiotic mismatch repair(GO:0000710)
0.0 0.1 GO:0072553 terminal button organization(GO:0072553)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0071020 post-spliceosomal complex(GO:0071020)
0.1 0.3 GO:0005595 collagen type XII trimer(GO:0005595)
0.1 0.5 GO:0031673 H zone(GO:0031673)
0.1 0.6 GO:0097209 epidermal lamellar body(GO:0097209)
0.1 0.2 GO:0005953 CAAX-protein geranylgeranyltransferase complex(GO:0005953)
0.0 0.1 GO:0044609 DBIRD complex(GO:0044609)
0.0 0.2 GO:0097635 extrinsic component of autophagosome membrane(GO:0097635)
0.0 0.2 GO:1990075 periciliary membrane compartment(GO:1990075)
0.0 0.1 GO:1990666 PCSK9-LDLR complex(GO:1990666)
0.0 0.1 GO:0031021 interphase microtubule organizing center(GO:0031021)
0.0 0.2 GO:0031467 Cul7-RING ubiquitin ligase complex(GO:0031467)
0.0 0.4 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.0 0.2 GO:0072558 NLRP1 inflammasome complex(GO:0072558) protease inhibitor complex(GO:0097179)
0.0 0.9 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.1 GO:0045293 MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
0.0 0.3 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0 0.1 GO:0030956 glutamyl-tRNA(Gln) amidotransferase complex(GO:0030956)
0.0 0.5 GO:0043219 lateral loop(GO:0043219)
0.0 0.1 GO:0016222 procollagen-proline 4-dioxygenase complex(GO:0016222)
0.0 0.1 GO:0097342 ripoptosome(GO:0097342)
0.0 0.2 GO:1990393 3M complex(GO:1990393)
0.0 0.2 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.0 0.2 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.0 0.7 GO:0031143 pseudopodium(GO:0031143)
0.0 0.1 GO:0032301 MutSalpha complex(GO:0032301)
0.0 0.4 GO:0005869 dynactin complex(GO:0005869)
0.0 0.2 GO:0044294 dendritic growth cone(GO:0044294)
0.0 0.2 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.0 0.1 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.0 0.1 GO:0071149 TEAD-2-YAP complex(GO:0071149)
0.0 0.2 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.0 0.1 GO:0071942 XPC complex(GO:0071942)
0.0 0.5 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.0 0.1 GO:1990578 perinuclear endoplasmic reticulum membrane(GO:1990578)
0.0 1.1 GO:0001533 cornified envelope(GO:0001533)
0.0 0.2 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.0 GO:0036195 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.0 0.1 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
0.0 0.1 GO:0000275 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275)
0.0 0.1 GO:0036156 inner dynein arm(GO:0036156)
0.0 0.3 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 0.1 GO:0043564 Ku70:Ku80 complex(GO:0043564)
0.0 0.4 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 0.5 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.0 GO:1990716 axonemal central apparatus(GO:1990716)
0.0 0.1 GO:1990812 growth cone filopodium(GO:1990812)
0.0 0.0 GO:0031379 RNA-directed RNA polymerase complex(GO:0031379)
0.0 0.0 GO:0070939 Dsl1p complex(GO:0070939) RZZ complex(GO:1990423)
0.0 0.3 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.0 0.1 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.0 1.9 GO:0005882 intermediate filament(GO:0005882)
0.0 0.5 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.0 GO:0005889 hydrogen:potassium-exchanging ATPase complex(GO:0005889)
0.0 0.0 GO:0031592 centrosomal corona(GO:0031592)
0.0 0.1 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.0 0.0 GO:0098844 postsynaptic endocytic zone membrane(GO:0098844)
0.0 0.0 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.0 0.3 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.2 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.2 GO:0042289 MHC class II protein binding(GO:0042289)
0.1 0.6 GO:0004556 alpha-amylase activity(GO:0004556)
0.1 0.5 GO:0060961 phospholipase D inhibitor activity(GO:0060961)
0.1 0.3 GO:0005150 interleukin-1, Type I receptor binding(GO:0005150)
0.1 0.3 GO:0061663 NEDD8 ligase activity(GO:0061663)
0.1 0.5 GO:0000386 second spliceosomal transesterification activity(GO:0000386)
0.1 0.2 GO:0046970 NAD-dependent histone deacetylase activity (H4-K16 specific)(GO:0046970)
0.1 0.2 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
0.1 0.3 GO:0043120 tumor necrosis factor binding(GO:0043120)
0.1 0.3 GO:0043812 phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812)
0.1 0.3 GO:0016316 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828)
0.1 0.2 GO:0004662 CAAX-protein geranylgeranyltransferase activity(GO:0004662)
0.0 0.2 GO:0003829 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.0 0.3 GO:0033989 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity(GO:0033989) 17-beta-hydroxysteroid dehydrogenase (NAD+) activity(GO:0044594)
0.0 0.2 GO:0004307 diacylglycerol cholinephosphotransferase activity(GO:0004142) ethanolaminephosphotransferase activity(GO:0004307)
0.0 0.1 GO:0016422 mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity(GO:0016422)
0.0 0.2 GO:0008457 beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity(GO:0008457) lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity(GO:0047256)
0.0 0.1 GO:0019781 NEDD8 activating enzyme activity(GO:0019781)
0.0 0.2 GO:0008260 3-oxoacid CoA-transferase activity(GO:0008260)
0.0 0.5 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.0 0.1 GO:0000404 heteroduplex DNA loop binding(GO:0000404)
0.0 0.1 GO:0004342 glucosamine-6-phosphate deaminase activity(GO:0004342)
0.0 0.9 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0 0.1 GO:0019961 interferon binding(GO:0019961)
0.0 0.1 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.0 0.4 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.0 0.2 GO:0102008 cytosolic dipeptidase activity(GO:0102008)
0.0 0.1 GO:0034736 sterol O-acyltransferase activity(GO:0004772) cholesterol O-acyltransferase activity(GO:0034736)
0.0 0.1 GO:0043739 G/U mismatch-specific uracil-DNA glycosylase activity(GO:0043739)
0.0 0.1 GO:0043398 HLH domain binding(GO:0043398)
0.0 0.1 GO:0015432 bile acid-exporting ATPase activity(GO:0015432)
0.0 0.1 GO:0070538 oleic acid binding(GO:0070538)
0.0 0.3 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.0 0.1 GO:0050567 glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity(GO:0050567)
0.0 0.2 GO:0017060 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity(GO:0017060)
0.0 0.4 GO:0004022 alcohol dehydrogenase (NAD) activity(GO:0004022)
0.0 0.1 GO:0033695 oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875)
0.0 0.3 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.0 0.6 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 0.1 GO:0004829 threonine-tRNA ligase activity(GO:0004829)
0.0 0.1 GO:0047391 alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391)
0.0 0.1 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0 0.6 GO:0045504 dynein heavy chain binding(GO:0045504)
0.0 0.1 GO:0047389 glycerophosphocholine phosphodiesterase activity(GO:0047389)
0.0 0.9 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.0 0.1 GO:0003826 alpha-ketoacid dehydrogenase activity(GO:0003826) 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity(GO:0003863)
0.0 0.1 GO:0004877 complement component C4b receptor activity(GO:0001861) complement component C3b receptor activity(GO:0004877)
0.0 0.1 GO:0071987 WD40-repeat domain binding(GO:0071987)
0.0 0.1 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
0.0 0.3 GO:0089720 caspase binding(GO:0089720)
0.0 0.1 GO:0033149 FFAT motif binding(GO:0033149)
0.0 0.1 GO:0034597 phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597)
0.0 0.1 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.0 3.3 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.1 GO:0000224 peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity(GO:0000224)
0.0 0.1 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.0 0.1 GO:0008746 NAD(P)+ transhydrogenase activity(GO:0008746) oxidoreductase activity, acting on NAD(P)H, NAD(P) as acceptor(GO:0016652)
0.0 0.1 GO:0050115 myosin-light-chain-phosphatase activity(GO:0050115)
0.0 0.1 GO:0032143 single thymine insertion binding(GO:0032143)
0.0 0.3 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.0 0.0 GO:0016418 S-acetyltransferase activity(GO:0016418)
0.0 0.2 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.0 0.1 GO:0047894 flavonol 3-sulfotransferase activity(GO:0047894)
0.0 0.1 GO:0002094 polyprenyltransferase activity(GO:0002094)
0.0 0.1 GO:0004882 androgen receptor activity(GO:0004882)
0.0 0.1 GO:0008745 N-acetylmuramoyl-L-alanine amidase activity(GO:0008745)
0.0 0.4 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 0.1 GO:0016428 tRNA (cytosine-5-)-methyltransferase activity(GO:0016428)
0.0 0.1 GO:0008670 2,4-dienoyl-CoA reductase (NADPH) activity(GO:0008670)
0.0 0.2 GO:0097016 L27 domain binding(GO:0097016)
0.0 0.1 GO:0070324 thyroid hormone binding(GO:0070324)
0.0 0.4 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0 0.1 GO:0003747 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.0 0.1 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.0 0.1 GO:0008900 hydrogen:potassium-exchanging ATPase activity(GO:0008900)
0.0 0.1 GO:0016297 oleoyl-[acyl-carrier-protein] hydrolase activity(GO:0004320) myristoyl-[acyl-carrier-protein] hydrolase activity(GO:0016295) palmitoyl-[acyl-carrier-protein] hydrolase activity(GO:0016296) acyl-[acyl-carrier-protein] hydrolase activity(GO:0016297)
0.0 0.3 GO:0032395 MHC class II receptor activity(GO:0032395)
0.0 0.1 GO:0061513 hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.0 0.6 GO:0031489 myosin V binding(GO:0031489)
0.0 0.1 GO:0070653 high-density lipoprotein particle receptor binding(GO:0070653)
0.0 0.1 GO:0047536 2-aminoadipate transaminase activity(GO:0047536)
0.0 0.1 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.0 0.0 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006) voltage-gated sodium channel activity involved in Purkinje myocyte action potential(GO:0086062)
0.0 0.2 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.0 0.3 GO:0000150 recombinase activity(GO:0000150)
0.0 0.1 GO:0080019 fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019)
0.0 0.3 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.0 0.1 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.0 0.2 GO:0019958 C-X-C chemokine binding(GO:0019958)
0.0 0.3 GO:0051011 microtubule minus-end binding(GO:0051011)
0.0 0.5 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 0.1 GO:0030229 very-low-density lipoprotein particle receptor activity(GO:0030229)
0.0 0.1 GO:0061665 SUMO ligase activity(GO:0061665)
0.0 0.1 GO:0044547 DNA topoisomerase binding(GO:0044547)
0.0 0.2 GO:0003831 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.0 0.1 GO:0004111 creatine kinase activity(GO:0004111)
0.0 0.0 GO:0019150 D-ribulokinase activity(GO:0019150)
0.0 0.0 GO:0017129 triglyceride binding(GO:0017129)
0.0 0.1 GO:0004948 calcitonin receptor activity(GO:0004948)
0.0 0.2 GO:0004568 chitinase activity(GO:0004568)
0.0 0.1 GO:0035514 DNA demethylase activity(GO:0035514)
0.0 0.1 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.0 0.8 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 0.1 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.0 0.3 GO:0008494 translation activator activity(GO:0008494)
0.0 0.1 GO:0016402 pristanoyl-CoA oxidase activity(GO:0016402)
0.0 0.1 GO:0042835 BRE binding(GO:0042835)
0.0 0.1 GO:0019798 procollagen-proline 4-dioxygenase activity(GO:0004656) procollagen-proline dioxygenase activity(GO:0019798)
0.0 0.1 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.0 0.1 GO:0017089 glycolipid transporter activity(GO:0017089)
0.0 0.1 GO:0043426 MRF binding(GO:0043426)
0.0 0.1 GO:0050610 oxidoreductase activity, acting on a sulfur group of donors, quinone or similar compound as acceptor(GO:0016672) glutathione dehydrogenase (ascorbate) activity(GO:0045174) methylarsonate reductase activity(GO:0050610)
0.0 0.4 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.4 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0 0.2 GO:0004303 estradiol 17-beta-dehydrogenase activity(GO:0004303)
0.0 0.7 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.0 GO:0010309 acireductone dioxygenase [iron(II)-requiring] activity(GO:0010309)
0.0 0.4 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.1 GO:0004784 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.0 0.3 GO:0001608 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.0 GO:0019237 centromeric DNA binding(GO:0019237)
0.0 0.1 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 0.1 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.0 0.2 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.0 0.1 GO:0097677 STAT family protein binding(GO:0097677)
0.0 0.0 GO:0031798 type 1 metabotropic glutamate receptor binding(GO:0031798)
0.0 0.4 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.3 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 0.2 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.3 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 0.0 GO:0016503 pheromone receptor activity(GO:0016503)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.0 ST GAQ PATHWAY G alpha q Pathway
0.0 0.6 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 1.8 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 2.6 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.0 0.8 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 1.1 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.0 0.8 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 0.2 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 3.6 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.0 0.6 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.0 0.9 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.0 0.4 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 0.9 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.0 1.0 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.3 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.0 0.3 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 0.5 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 0.3 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 0.7 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 0.4 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.3 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.1 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.0 0.3 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.0 0.2 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.0 0.3 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.5 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 0.2 REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1 Genes involved in Signaling by activated point mutants of FGFR1
0.0 0.2 REACTOME XENOBIOTICS Genes involved in Xenobiotics