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SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for MAF_NRL

Z-value: 0.39

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Transcription factors associated with MAF_NRL

Gene Symbol Gene ID Gene Info
ENSG00000178573.6 MAF bZIP transcription factor
ENSG00000129535.8 neural retina leucine zipper

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NRLhg19_v2_chr14_-_24584138_245842230.454.6e-02Click!
MAFhg19_v2_chr16_-_79634595_79634620-0.262.7e-01Click!

Activity profile of MAF_NRL motif

Sorted Z-values of MAF_NRL motif

Promoter Log-likelihood Transcript Gene Gene Info
chr5_-_156390230 0.95 ENST00000407087.3
ENST00000274532.2
T-cell immunoglobulin and mucin domain containing 4
chr18_-_25616519 0.58 ENST00000399380.3
cadherin 2, type 1, N-cadherin (neuronal)
chr12_+_47610315 0.53 ENST00000548348.1
ENST00000549500.1
PC-esterase domain containing 1B
chr5_+_175298487 0.47 ENST00000393745.3
complexin 2
chr8_-_19615435 0.46 ENST00000523262.1
chondroitin sulfate N-acetylgalactosaminyltransferase 1
chr11_-_2924720 0.44 ENST00000455942.2
solute carrier family 22 (organic cation transporter), member 18 antisense
chr9_-_75567962 0.44 ENST00000297785.3
ENST00000376939.1
aldehyde dehydrogenase 1 family, member A1
chr17_-_73874654 0.43 ENST00000254816.2
tripartite motif containing 47
chr11_+_123430948 0.42 ENST00000529432.1
ENST00000534764.1
GRAM domain containing 1B
chr5_+_175298573 0.39 ENST00000512824.1
complexin 2
chr7_-_35013217 0.39 ENST00000446375.1
dpy-19-like 1 (C. elegans)
chr15_-_88799661 0.37 ENST00000360948.2
ENST00000357724.2
ENST00000355254.2
ENST00000317501.3
neurotrophic tyrosine kinase, receptor, type 3
chr5_+_175298674 0.37 ENST00000514150.1
complexin 2
chr8_+_32579321 0.36 ENST00000522402.1
neuregulin 1
chr8_+_32579341 0.35 ENST00000519240.1
ENST00000539990.1
neuregulin 1
chr15_-_72514866 0.35 ENST00000562997.1
pyruvate kinase, muscle
chr17_-_38520067 0.35 ENST00000337376.4
ENST00000578689.1
gap junction protein, delta 3, 31.9kDa
chr15_-_75248954 0.35 ENST00000499788.2
ribonuclease P/MRP 25kDa subunit
chr17_-_74489215 0.31 ENST00000585701.1
ENST00000591192.1
ENST00000589526.1
rhomboid 5 homolog 2 (Drosophila)
chr19_+_7445850 0.31 ENST00000593531.1
Rho guanine nucleotide exchange factor 18
chr1_-_153517473 0.30 ENST00000368715.1
S100 calcium binding protein A4
chrX_-_153775426 0.30 ENST00000393562.2
glucose-6-phosphate dehydrogenase
chr10_+_31610064 0.30 ENST00000446923.2
ENST00000559476.1
zinc finger E-box binding homeobox 1
chr11_-_124632179 0.30 ENST00000278927.5
ENST00000442070.2
ENST00000444566.1
ENST00000435477.1
endothelial cell adhesion molecule
chr16_+_2510081 0.29 ENST00000361837.4
ENST00000569496.1
ENST00000567489.1
ENST00000563531.1
ENST00000483320.1
chromosome 16 open reading frame 59
chr11_-_10920838 0.29 ENST00000503469.2
CTD-2003C8.2
chr17_+_32582293 0.29 ENST00000580907.1
ENST00000225831.4
chemokine (C-C motif) ligand 2
chr19_+_39759154 0.28 ENST00000331982.5
interferon, lambda 2
chr2_+_234296792 0.27 ENST00000409813.3
diacylglycerol kinase, delta 130kDa
chr10_+_70980051 0.26 ENST00000354624.5
ENST00000395086.2
hexokinase domain containing 1
chr5_-_142784003 0.26 ENST00000416954.2
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
chr7_-_94285472 0.26 ENST00000437425.2
ENST00000447873.1
ENST00000415788.2
sarcoglycan, epsilon
chr17_+_73606766 0.26 ENST00000578462.1
myosin XVB pseudogene
chr7_-_32111009 0.26 ENST00000396184.3
ENST00000396189.2
ENST00000321453.7
phosphodiesterase 1C, calmodulin-dependent 70kDa
chr15_-_27184664 0.26 ENST00000541819.2
gamma-aminobutyric acid (GABA) A receptor, beta 3
chr7_-_94285511 0.25 ENST00000265735.7
sarcoglycan, epsilon
chr1_+_163291680 0.25 ENST00000450453.2
ENST00000524800.1
ENST00000442820.1
ENST00000367900.3
NUF2, NDC80 kinetochore complex component
chr8_+_145438870 0.24 ENST00000527931.1
family with sequence similarity 203, member B
chr17_-_28619059 0.24 ENST00000580709.1
bleomycin hydrolase
chr2_-_190044480 0.24 ENST00000374866.3
collagen, type V, alpha 2
chrX_-_24045303 0.24 ENST00000328046.8
kelch-like family member 15
chr7_-_94285402 0.23 ENST00000428696.2
ENST00000445866.2
sarcoglycan, epsilon
chr19_+_7599792 0.22 ENST00000600942.1
ENST00000593924.1
patatin-like phospholipase domain containing 6
chr17_-_63052929 0.22 ENST00000439174.2
guanine nucleotide binding protein (G protein), alpha 13
chr2_+_135011731 0.22 ENST00000281923.2
mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase
chr17_+_18625336 0.22 ENST00000395671.4
ENST00000571542.1
ENST00000395672.2
ENST00000414850.2
ENST00000424146.2
tripartite motif containing 16-like
chr19_-_38747172 0.22 ENST00000347262.4
ENST00000591585.1
ENST00000301242.4
protein phosphatase 1, regulatory (inhibitor) subunit 14A
chr5_+_155753745 0.22 ENST00000435422.3
ENST00000337851.4
ENST00000447401.1
sarcoglycan, delta (35kDa dystrophin-associated glycoprotein)
chr1_-_226595648 0.22 ENST00000366790.3
poly (ADP-ribose) polymerase 1
chr2_+_71127699 0.21 ENST00000234392.2
ventral anterior homeobox 2
chr1_-_197115818 0.20 ENST00000367409.4
ENST00000294732.7
asp (abnormal spindle) homolog, microcephaly associated (Drosophila)
chr3_-_88108192 0.20 ENST00000309534.6
CGG triplet repeat binding protein 1
chr6_-_166401402 0.20 ENST00000581850.1
ENST00000444465.1
long intergenic non-protein coding RNA 473
chr12_+_53662073 0.19 ENST00000553219.1
ENST00000257934.4
extra spindle pole bodies homolog 1 (S. cerevisiae)
chr19_-_39735646 0.19 ENST00000413851.2
interferon, lambda 3
chr10_+_94590910 0.19 ENST00000371547.4
exocyst complex component 6
chr22_+_31277661 0.19 ENST00000454145.1
ENST00000453621.1
ENST00000431368.1
ENST00000535268.1
oxysterol binding protein 2
chr6_-_166401527 0.18 ENST00000455853.1
ENST00000584911.1
long intergenic non-protein coding RNA 473
chr15_-_82338460 0.18 ENST00000558133.1
ENST00000329713.4
mex-3 RNA binding family member B
chr3_-_9811595 0.18 ENST00000256460.3
calcium/calmodulin-dependent protein kinase I
chr10_+_115469134 0.18 ENST00000452490.2
caspase 7, apoptosis-related cysteine peptidase
chr7_-_32110451 0.18 ENST00000396191.1
ENST00000396182.2
phosphodiesterase 1C, calmodulin-dependent 70kDa
chr11_-_2924970 0.18 ENST00000533594.1
solute carrier family 22 (organic cation transporter), member 18 antisense
chr16_+_57844549 0.18 ENST00000564282.1
uncharacterized protein LOC388282
chr2_-_191878162 0.17 ENST00000540176.1
signal transducer and activator of transcription 1, 91kDa
chr5_-_142784101 0.17 ENST00000503201.1
ENST00000502892.1
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
chr16_+_71392616 0.17 ENST00000349553.5
ENST00000302628.4
ENST00000562305.1
calbindin 2
chr2_-_188419200 0.17 ENST00000233156.3
ENST00000426055.1
ENST00000453013.1
ENST00000417013.1
tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
chr22_-_36013368 0.17 ENST00000442617.1
ENST00000397326.2
ENST00000397328.1
ENST00000451685.1
myoglobin
chr19_+_45417504 0.17 ENST00000588750.1
ENST00000588802.1
apolipoprotein C-I
chr3_-_88108212 0.17 ENST00000482016.1
CGG triplet repeat binding protein 1
chr9_+_132427883 0.17 ENST00000372469.4
paired related homeobox 2
chr1_+_39876151 0.17 ENST00000530275.1
KIAA0754
chr7_+_127527965 0.17 ENST00000486037.1
staphylococcal nuclease and tudor domain containing 1
chr19_+_45417921 0.17 ENST00000252491.4
ENST00000592885.1
ENST00000589781.1
apolipoprotein C-I
chr19_-_40030861 0.16 ENST00000390658.2
EP300 interacting inhibitor of differentiation 2
chr20_+_42187682 0.16 ENST00000373092.3
ENST00000373077.1
serum/glucocorticoid regulated kinase 2
chr4_+_41540160 0.16 ENST00000503057.1
ENST00000511496.1
LIM and calponin homology domains 1
chr2_-_234763147 0.15 ENST00000411486.2
ENST00000432087.1
ENST00000441687.1
ENST00000414924.1
Holliday junction recognition protein
chr19_-_38746979 0.15 ENST00000591291.1
protein phosphatase 1, regulatory (inhibitor) subunit 14A
chr3_+_183894737 0.15 ENST00000432591.1
ENST00000431779.1
adaptor-related protein complex 2, mu 1 subunit
chr19_-_46285736 0.15 ENST00000291270.4
ENST00000447742.2
ENST00000354227.5
dystrophia myotonica-protein kinase
chr19_+_52076425 0.15 ENST00000436511.2
zinc finger protein 175
chr15_-_71184724 0.15 ENST00000560604.1
THAP domain containing 10
chr11_-_10829851 0.15 ENST00000532082.1
eukaryotic translation initiation factor 4 gamma, 2
chr19_-_18391708 0.15 ENST00000600972.1
jun D proto-oncogene
chr2_-_188419078 0.15 ENST00000437725.1
ENST00000409676.1
ENST00000339091.4
ENST00000420747.1
tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
chr14_-_100046444 0.15 ENST00000554996.1
coiled-coil domain containing 85C
chr4_-_186125077 0.15 ENST00000458385.2
ENST00000514798.1
ENST00000296775.6
KIAA1430
chr12_-_58220078 0.15 ENST00000549039.1
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2
chr1_-_22222764 0.14 ENST00000439717.2
ENST00000412328.1
heparan sulfate proteoglycan 2
chr8_+_26434578 0.14 ENST00000493789.2
dihydropyrimidinase-like 2
chr16_-_46655538 0.14 ENST00000303383.3
SHC SH2-domain binding protein 1
chr2_-_191878681 0.14 ENST00000409465.1
signal transducer and activator of transcription 1, 91kDa
chr10_+_75757863 0.14 ENST00000372755.3
ENST00000211998.4
ENST00000417648.2
vinculin
chr1_+_45205591 0.14 ENST00000455186.1
kinesin family member 2C
chr11_-_45928830 0.14 ENST00000449465.1
chromosome 11 open reading frame 94
chr9_+_133589333 0.14 ENST00000372348.2
ENST00000393293.4
c-abl oncogene 1, non-receptor tyrosine kinase
chr2_+_101591314 0.14 ENST00000450763.1
neuronal PAS domain protein 2
chr8_-_108510224 0.14 ENST00000517746.1
ENST00000297450.3
angiopoietin 1
chr7_+_26331541 0.14 ENST00000416246.1
ENST00000338523.4
ENST00000412416.1
sorting nexin 10
chr15_+_59665194 0.13 ENST00000560394.1
family with sequence similarity 81, member A
chr20_-_48530230 0.13 ENST00000422556.1
spermatogenesis associated 2
chr14_+_105957402 0.13 ENST00000421892.1
ENST00000334656.7
ENST00000451719.1
ENST00000392522.3
ENST00000392523.4
ENST00000354560.6
ENST00000450383.1
chromosome 14 open reading frame 80
chr14_+_96829814 0.13 ENST00000555181.1
ENST00000553699.1
ENST00000554182.1
GSK3B interacting protein
chr19_+_50887585 0.13 ENST00000440232.2
ENST00000601098.1
ENST00000599857.1
ENST00000593887.1
polymerase (DNA directed), delta 1, catalytic subunit
chr5_-_90610200 0.13 ENST00000511918.1
ENST00000513626.1
ENST00000607854.1
lung cancer associated transcript 1 (non-protein coding)
RP11-213H15.4
chr11_+_61520075 0.13 ENST00000278836.5
myelin regulatory factor
chr2_+_97454321 0.13 ENST00000540067.1
cyclin M4
chr15_-_59041954 0.13 ENST00000439637.1
ENST00000558004.1
ADAM metallopeptidase domain 10
chr17_-_73389737 0.13 ENST00000392563.1
growth factor receptor-bound protein 2
chr3_+_158991025 0.13 ENST00000337808.6
IQCJ-SCHIP1 readthrough
chr1_+_41447609 0.13 ENST00000543104.1
CTP synthase 1
chr16_-_31076332 0.13 ENST00000539836.3
ENST00000535577.1
ENST00000442862.2
zinc finger protein 668
chr12_+_52626898 0.13 ENST00000331817.5
keratin 7
chr11_-_71781096 0.13 ENST00000535087.1
ENST00000535838.1
nuclear mitotic apparatus protein 1
chr9_-_116840728 0.13 ENST00000265132.3
alpha-1-microglobulin/bikunin precursor
chr6_-_127780510 0.13 ENST00000487331.2
ENST00000483725.3
KIAA0408
chr13_-_44735393 0.13 ENST00000400419.1
small integral membrane protein 2
chr2_+_152214098 0.13 ENST00000243347.3
tumor necrosis factor, alpha-induced protein 6
chr3_-_13114587 0.13 ENST00000429247.1
IQ motif and Sec7 domain 1
chr7_-_2883650 0.13 ENST00000544127.1
guanine nucleotide binding protein (G protein) alpha 12
chr15_-_66858298 0.13 ENST00000537670.1
lactase-like
chrX_-_153583257 0.12 ENST00000438732.1
filamin A, alpha
chr1_+_6105974 0.12 ENST00000378083.3
potassium voltage-gated channel, shaker-related subfamily, beta member 2
chr14_+_57735636 0.12 ENST00000556995.1
adaptor-related protein complex 5, mu 1 subunit
chr17_-_73389854 0.12 ENST00000578961.1
ENST00000392564.1
ENST00000582582.1
growth factor receptor-bound protein 2
chr12_-_53297432 0.12 ENST00000546900.1
keratin 8
chr19_-_46285646 0.12 ENST00000458663.2
dystrophia myotonica-protein kinase
chr15_+_99433570 0.12 ENST00000558898.1
insulin-like growth factor 1 receptor
chr2_+_189156389 0.12 ENST00000409843.1
GULP, engulfment adaptor PTB domain containing 1
chr3_+_88108381 0.12 ENST00000473136.1
Uncharacterized protein
chr17_+_30771279 0.12 ENST00000261712.3
ENST00000578213.1
ENST00000457654.2
ENST00000579451.1
proteasome (prosome, macropain) 26S subunit, non-ATPase, 11
chr1_+_163291732 0.12 ENST00000271452.3
NUF2, NDC80 kinetochore complex component
chr12_+_53662110 0.12 ENST00000552462.1
extra spindle pole bodies homolog 1 (S. cerevisiae)
chr14_+_23067166 0.12 ENST00000216327.6
ENST00000542041.1
abhydrolase domain containing 4
chr16_-_15180257 0.12 ENST00000540462.1
RRN3 RNA polymerase I transcription factor homolog (S. cerevisiae)
chr20_+_33759854 0.12 ENST00000216968.4
protein C receptor, endothelial
chr1_-_1763721 0.12 ENST00000437146.1
guanine nucleotide binding protein (G protein), beta polypeptide 1
chr17_-_56065540 0.12 ENST00000583932.1
vascular endothelial zinc finger 1
chr14_+_96829886 0.11 ENST00000556095.1
GSK3B interacting protein
chr14_+_93118813 0.11 ENST00000556418.1
Ras and Rab interactor 3
chr14_+_105927191 0.11 ENST00000550551.1
metastasis associated 1
chr10_-_98347063 0.11 ENST00000443638.1
transmembrane 9 superfamily member 3
chr14_-_51562745 0.11 ENST00000298355.3
tripartite motif containing 9
chr9_+_126777676 0.11 ENST00000488674.2
LIM homeobox 2
chr14_-_23395623 0.11 ENST00000556043.1
protein arginine methyltransferase 5
chr2_+_196521903 0.11 ENST00000541054.1
solute carrier family 39 (zinc transporter), member 10
chr19_+_55795493 0.11 ENST00000309383.1
BR serine/threonine kinase 1
chr11_+_64808675 0.11 ENST00000529996.1
SAC3 domain containing 1
chr5_+_179125368 0.11 ENST00000502296.1
ENST00000504734.1
ENST00000415618.2
calnexin
chr3_-_47484661 0.11 ENST00000495603.2
SREBF chaperone
chr6_+_32936942 0.11 ENST00000496118.2
bromodomain containing 2
chr12_+_56075330 0.11 ENST00000394252.3
methyltransferase like 7B
chr12_-_105352047 0.11 ENST00000432951.1
ENST00000415674.1
ENST00000424946.1
solute carrier family 41 (magnesium transporter), member 2
chr19_-_10450287 0.11 ENST00000589261.1
ENST00000590569.1
ENST00000589580.1
ENST00000589249.1
intercellular adhesion molecule 3
chr14_-_57735528 0.11 ENST00000340918.7
ENST00000413566.2
exocyst complex component 5
chr17_+_27573875 0.11 ENST00000225387.3
crystallin, beta A1
chr17_-_54893250 0.11 ENST00000397862.2
chromosome 17 open reading frame 67
chr10_-_118502070 0.11 ENST00000369209.3
heat shock 70kDa protein 12A
chr19_+_45418067 0.11 ENST00000589078.1
ENST00000586638.1
apolipoprotein C-I
chr2_-_97536490 0.11 ENST00000449330.1
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C
chr16_-_1429674 0.10 ENST00000403703.1
ENST00000397464.1
ENST00000402641.2
unkempt family zinc finger-like
chr19_+_45417812 0.10 ENST00000592535.1
apolipoprotein C-I
chr19_-_50381606 0.10 ENST00000391830.1
AKT1 substrate 1 (proline-rich)
chr20_-_60942326 0.10 ENST00000370677.3
ENST00000370692.3
laminin, alpha 5
chr15_-_70994612 0.10 ENST00000558758.1
ENST00000379983.2
ENST00000560441.1
uveal autoantigen with coiled-coil domains and ankyrin repeats
chr9_-_112260531 0.10 ENST00000374541.2
ENST00000262539.3
protein tyrosine phosphatase, non-receptor type 3
chr5_+_150040403 0.10 ENST00000517768.1
ENST00000297130.4
myozenin 3
chr22_-_39150947 0.10 ENST00000411587.2
ENST00000420859.1
ENST00000452294.1
ENST00000456894.1
Sad1 and UNC84 domain containing 2
chr15_+_71839566 0.10 ENST00000357769.4
thrombospondin, type I, domain containing 4
chr1_+_178694408 0.10 ENST00000324778.5
Ral GEF with PH domain and SH3 binding motif 2
chr2_+_173940163 0.10 ENST00000539448.1
Mitogen-activated protein kinase kinase kinase MLT
chr3_-_138553779 0.10 ENST00000461451.1
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
chr7_+_114562909 0.10 ENST00000423503.1
ENST00000427207.1
MyoD family inhibitor domain containing
chr15_+_59903975 0.10 ENST00000560585.1
ENST00000396065.1
glucosaminyl (N-acetyl) transferase 3, mucin type
chr3_-_119182506 0.10 ENST00000468676.1
transmembrane protein 39A
chr1_+_233749739 0.10 ENST00000366621.3
potassium channel, subfamily K, member 1
chr4_+_78978724 0.10 ENST00000325942.6
ENST00000264895.6
ENST00000264899.6
Fraser syndrome 1
chr2_+_145780739 0.10 ENST00000597173.1
ENST00000602108.1
ENST00000420472.1
testis expressed 41 (non-protein coding)
chr2_+_189156586 0.10 ENST00000409830.1
GULP, engulfment adaptor PTB domain containing 1
chr2_+_172950227 0.10 ENST00000341900.6
distal-less homeobox 1
chr22_+_24577183 0.10 ENST00000358321.3
sushi domain containing 2
chr3_+_98699880 0.10 ENST00000473756.1
long intergenic non-protein coding RNA 973
chr19_+_38880695 0.10 ENST00000587947.1
ENST00000338502.4
sprouty-related, EVH1 domain containing 3
chr22_-_44708731 0.10 ENST00000381176.4
KIAA1644
chr19_-_10450328 0.10 ENST00000160262.5
intercellular adhesion molecule 3
chr13_+_93879085 0.10 ENST00000377047.4
glypican 6
chr2_+_87754989 0.10 ENST00000409898.2
ENST00000419680.2
ENST00000414584.1
ENST00000455131.1
long intergenic non-protein coding RNA 152
chr14_+_61447832 0.10 ENST00000354886.2
ENST00000267488.4
solute carrier family 38, member 6
chr1_+_42846443 0.10 ENST00000410070.2
ENST00000431473.3
ribosomal modification protein rimK-like family member A
chr20_-_48099182 0.10 ENST00000371741.4
potassium voltage-gated channel, Shab-related subfamily, member 1
chr11_-_57298187 0.10 ENST00000525158.1
ENST00000257245.4
ENST00000525587.1
translocase of inner mitochondrial membrane 10 homolog (yeast)
chr17_-_3595181 0.09 ENST00000552050.1
purinergic receptor P2X, ligand-gated ion channel, 5
chr6_+_160693591 0.09 ENST00000419196.1
RP1-276N6.2
chr14_-_21562648 0.09 ENST00000555270.1
zinc finger protein 219
chr19_-_55895966 0.09 ENST00000444469.3
transmembrane protein 238
chr9_+_114393634 0.09 ENST00000556107.1
ENST00000374294.3
DnaJ (Hsp40) homolog, subfamily C , member 25
DNAJC25-GNG10 readthrough
chr2_+_189156721 0.09 ENST00000409927.1
ENST00000409805.1
GULP, engulfment adaptor PTB domain containing 1
chr17_-_18218237 0.09 ENST00000542570.1
topoisomerase (DNA) III alpha

Network of associatons between targets according to the STRING database.

First level regulatory network of MAF_NRL

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0010900 negative regulation of phosphatidylcholine catabolic process(GO:0010900)
0.1 0.1 GO:0051389 inactivation of MAPKK activity(GO:0051389)
0.1 0.3 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.1 0.4 GO:0046725 negative regulation by virus of viral protein levels in host cell(GO:0046725) negative regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072308)
0.1 0.3 GO:2000502 negative regulation of natural killer cell chemotaxis(GO:2000502)
0.1 0.4 GO:0048691 modulation by virus of host transcription(GO:0019056) positive regulation of sprouting of injured axon(GO:0048687) positive regulation of axon extension involved in regeneration(GO:0048691) modulation by symbiont of host transcription(GO:0052026)
0.1 0.7 GO:0021842 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842)
0.1 0.3 GO:0018312 peptidyl-serine ADP-ribosylation(GO:0018312)
0.1 0.3 GO:0045875 negative regulation of sister chromatid cohesion(GO:0045875)
0.1 0.4 GO:0006001 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
0.1 0.4 GO:1903615 regulation of protein tyrosine phosphatase activity(GO:1903613) positive regulation of protein tyrosine phosphatase activity(GO:1903615)
0.1 0.2 GO:0009786 regulation of asymmetric cell division(GO:0009786)
0.1 0.6 GO:2000809 positive regulation of synaptic vesicle clustering(GO:2000809)
0.1 0.5 GO:0050653 chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0050653)
0.1 0.3 GO:0009051 pentose-phosphate shunt, oxidative branch(GO:0009051)
0.0 0.2 GO:0035544 negative regulation of SNARE complex assembly(GO:0035544)
0.0 0.3 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
0.0 0.0 GO:0035562 negative regulation of chromatin binding(GO:0035562)
0.0 0.1 GO:1990051 activation of protein kinase C activity(GO:1990051)
0.0 1.3 GO:0031915 positive regulation of synaptic plasticity(GO:0031915)
0.0 0.1 GO:1902396 protein localization to bicellular tight junction(GO:1902396)
0.0 0.3 GO:0051835 positive regulation of synapse structural plasticity(GO:0051835)
0.0 0.1 GO:0071663 granzyme B production(GO:0071613) regulation of granzyme B production(GO:0071661) positive regulation of granzyme B production(GO:0071663)
0.0 0.2 GO:0031047 gene silencing by RNA(GO:0031047)
0.0 0.1 GO:1905000 regulation of membrane repolarization during atrial cardiac muscle cell action potential(GO:1905000)
0.0 0.4 GO:0042866 pyruvate biosynthetic process(GO:0042866)
0.0 0.3 GO:0071630 nucleus-associated proteasomal ubiquitin-dependent protein catabolic process(GO:0071630)
0.0 0.4 GO:0018406 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.0 0.5 GO:0043402 glucocorticoid mediated signaling pathway(GO:0043402)
0.0 0.1 GO:0002426 immunoglobulin production in mucosal tissue(GO:0002426)
0.0 0.3 GO:0043418 homocysteine catabolic process(GO:0043418)
0.0 0.1 GO:1902868 regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment(GO:0021882) cerebral cortex GABAergic interneuron fate commitment(GO:0021893) positive regulation of neural retina development(GO:0061075) positive regulation of retina development in camera-type eye(GO:1902868) positive regulation of amacrine cell differentiation(GO:1902871)
0.0 0.2 GO:0007181 transforming growth factor beta receptor complex assembly(GO:0007181)
0.0 0.3 GO:0045602 negative regulation of endothelial cell differentiation(GO:0045602)
0.0 0.1 GO:0003032 detection of oxygen(GO:0003032)
0.0 0.1 GO:0042732 D-xylose metabolic process(GO:0042732)
0.0 0.1 GO:1900275 negative regulation of phospholipase C activity(GO:1900275) regulation of proteinase activated receptor activity(GO:1900276) negative regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900737)
0.0 0.1 GO:0051795 positive regulation of catagen(GO:0051795) frontal suture morphogenesis(GO:0060364) activation of meiosis(GO:0090427)
0.0 0.2 GO:0031444 slow-twitch skeletal muscle fiber contraction(GO:0031444)
0.0 0.1 GO:0051088 PMA-inducible membrane protein ectodomain proteolysis(GO:0051088)
0.0 0.2 GO:0010897 negative regulation of triglyceride catabolic process(GO:0010897)
0.0 0.1 GO:0060827 regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060827) negative regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060829)
0.0 0.1 GO:0044210 'de novo' CTP biosynthetic process(GO:0044210)
0.0 0.1 GO:0010701 positive regulation of norepinephrine secretion(GO:0010701)
0.0 0.1 GO:0045014 carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014)
0.0 0.1 GO:0031456 glycine betaine biosynthetic process from choline(GO:0019285) glycine betaine metabolic process(GO:0031455) glycine betaine biosynthetic process(GO:0031456)
0.0 0.1 GO:0006287 base-excision repair, gap-filling(GO:0006287)
0.0 0.1 GO:1903939 negative regulation of histone H3-K9 dimethylation(GO:1900110) regulation of TORC2 signaling(GO:1903939)
0.0 0.2 GO:0030210 heparin metabolic process(GO:0030202) heparin biosynthetic process(GO:0030210)
0.0 0.1 GO:0021966 corticospinal neuron axon guidance(GO:0021966)
0.0 0.0 GO:0000041 transition metal ion transport(GO:0000041)
0.0 0.2 GO:0010737 protein kinase A signaling(GO:0010737) regulation of protein kinase A signaling(GO:0010738)
0.0 0.2 GO:0032485 Ral protein signal transduction(GO:0032484) regulation of Ral protein signal transduction(GO:0032485)
0.0 0.1 GO:0003363 lamellipodium assembly involved in ameboidal cell migration(GO:0003363) extension of a leading process involved in cell motility in cerebral cortex radial glia guided migration(GO:0021816)
0.0 0.1 GO:0060298 positive regulation of sarcomere organization(GO:0060298)
0.0 0.3 GO:0051823 regulation of synapse structural plasticity(GO:0051823)
0.0 0.1 GO:2000230 negative regulation of pancreatic stellate cell proliferation(GO:2000230)
0.0 0.1 GO:0033031 positive regulation of neutrophil apoptotic process(GO:0033031)
0.0 0.1 GO:0051005 negative regulation of lipoprotein lipase activity(GO:0051005)
0.0 0.1 GO:1902499 positive regulation of protein autoubiquitination(GO:1902499)
0.0 0.1 GO:0007195 adenylate cyclase-inhibiting dopamine receptor signaling pathway(GO:0007195) positive regulation of dopamine receptor signaling pathway(GO:0060161)
0.0 0.1 GO:0070901 mitochondrial tRNA methylation(GO:0070901)
0.0 0.4 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.0 0.1 GO:2000616 negative regulation of histone H3-K9 acetylation(GO:2000616)
0.0 0.1 GO:2000870 regulation of progesterone secretion(GO:2000870)
0.0 0.1 GO:0010652 regulation of cell communication by chemical coupling(GO:0010645) positive regulation of cell communication by chemical coupling(GO:0010652)
0.0 0.1 GO:0001180 transcription initiation from RNA polymerase I promoter for nuclear large rRNA transcript(GO:0001180)
0.0 0.1 GO:0072733 response to staurosporine(GO:0072733) cellular response to staurosporine(GO:0072734)
0.0 0.1 GO:0010693 negative regulation of alkaline phosphatase activity(GO:0010693)
0.0 0.4 GO:0016264 gap junction assembly(GO:0016264)
0.0 0.1 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.0 0.1 GO:0035633 maintenance of blood-brain barrier(GO:0035633)
0.0 0.1 GO:0003335 corneocyte development(GO:0003335)
0.0 0.2 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.0 0.1 GO:0070995 NADPH oxidation(GO:0070995)
0.0 0.3 GO:0034776 response to histamine(GO:0034776) cellular response to histamine(GO:0071420)
0.0 0.1 GO:0045541 negative regulation of cholesterol biosynthetic process(GO:0045541) positive regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045716) negative regulation of cholesterol metabolic process(GO:0090206)
0.0 0.1 GO:0071475 cellular hyperosmotic salinity response(GO:0071475)
0.0 0.1 GO:0010157 response to chlorate(GO:0010157)
0.0 0.1 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.0 0.1 GO:0032887 regulation of spindle elongation(GO:0032887) regulation of mitotic spindle elongation(GO:0032888) anastral spindle assembly(GO:0055048) protein localization to spindle pole body(GO:0071988) regulation of protein localization to spindle pole body(GO:1902363) positive regulation of protein localization to spindle pole body(GO:1902365) positive regulation of mitotic spindle elongation(GO:1902846)
0.0 0.0 GO:0044029 DNA hypomethylation(GO:0044028) hypomethylation of CpG island(GO:0044029)
0.0 0.0 GO:0044342 type B pancreatic cell proliferation(GO:0044342)
0.0 0.0 GO:0070904 L-ascorbic acid transport(GO:0015882) transepithelial L-ascorbic acid transport(GO:0070904)
0.0 0.1 GO:0071386 cellular response to corticosterone stimulus(GO:0071386)
0.0 0.0 GO:0060406 positive regulation of penile erection(GO:0060406)
0.0 0.1 GO:0001550 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
0.0 0.0 GO:1990918 double-strand break repair involved in meiotic recombination(GO:1990918)
0.0 0.1 GO:0032286 central nervous system myelin maintenance(GO:0032286)
0.0 0.2 GO:0006451 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.0 0.1 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
0.0 0.0 GO:0002432 granuloma formation(GO:0002432)
0.0 0.0 GO:0006422 aspartyl-tRNA aminoacylation(GO:0006422)
0.0 0.0 GO:0042245 RNA repair(GO:0042245)
0.0 0.2 GO:0007220 Notch receptor processing(GO:0007220)
0.0 0.1 GO:1901525 negative regulation of macromitophagy(GO:1901525)
0.0 0.1 GO:0061687 detoxification of inorganic compound(GO:0061687)
0.0 0.1 GO:2000210 positive regulation of anoikis(GO:2000210)
0.0 0.0 GO:1901594 detection of temperature stimulus involved in thermoception(GO:0050960) response to capsazepine(GO:1901594)
0.0 0.3 GO:0002385 mucosal immune response(GO:0002385)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.3 GO:0070033 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033) synaptobrevin 2-SNAP-25-syntaxin-3-complexin complex(GO:0070554)
0.1 1.0 GO:0016012 sarcoglycan complex(GO:0016012)
0.1 0.4 GO:1902912 pyruvate kinase complex(GO:1902912)
0.1 0.2 GO:0005588 collagen type V trimer(GO:0005588)
0.1 0.4 GO:0031262 Ndc80 complex(GO:0031262)
0.0 0.3 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.0 0.3 GO:0070436 Grb2-EGFR complex(GO:0070436)
0.0 0.8 GO:0005916 fascia adherens(GO:0005916)
0.0 0.1 GO:0031523 Myb complex(GO:0031523)
0.0 0.1 GO:0039714 viral factory(GO:0039713) cytoplasmic viral factory(GO:0039714) host cell viral assembly compartment(GO:0072517)
0.0 0.1 GO:0002947 tumor necrosis factor receptor superfamily complex(GO:0002947)
0.0 0.1 GO:0005940 septin ring(GO:0005940) septin collar(GO:0032173)
0.0 0.1 GO:0002139 stereocilia coupling link(GO:0002139)
0.0 0.1 GO:1990031 pinceau fiber(GO:1990031)
0.0 0.1 GO:0043260 laminin-11 complex(GO:0043260)
0.0 0.2 GO:0044294 dendritic growth cone(GO:0044294)
0.0 0.1 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.0 0.1 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
0.0 0.3 GO:0036449 microtubule minus-end(GO:0036449)
0.0 0.2 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.0 0.1 GO:0030689 Noc complex(GO:0030689)
0.0 0.5 GO:0042627 chylomicron(GO:0042627)
0.0 0.1 GO:0034667 integrin alpha3-beta1 complex(GO:0034667)
0.0 0.1 GO:0031510 SUMO activating enzyme complex(GO:0031510)
0.0 0.1 GO:0035976 AP1 complex(GO:0035976)
0.0 0.1 GO:0043527 tRNA methyltransferase complex(GO:0043527)
0.0 0.1 GO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.0 0.7 GO:0030673 axolemma(GO:0030673)
0.0 0.1 GO:0036064 ciliary basal body(GO:0036064)
0.0 0.2 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.0 0.4 GO:0005922 connexon complex(GO:0005922)
0.0 0.1 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 0.1 GO:0043564 Ku70:Ku80 complex(GO:0043564)
0.0 0.1 GO:0098797 plasma membrane protein complex(GO:0098797)
0.0 0.0 GO:0070993 translation preinitiation complex(GO:0070993)
0.0 0.1 GO:0036454 insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.0 0.2 GO:0005921 gap junction(GO:0005921)
0.0 0.1 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 0.1 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.0 0.1 GO:1990393 3M complex(GO:1990393)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:1990404 protein ADP-ribosylase activity(GO:1990404)
0.1 0.5 GO:0008955 peptidoglycan glycosyltransferase activity(GO:0008955)
0.1 0.7 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.1 0.3 GO:0004345 glucose-6-phosphate dehydrogenase activity(GO:0004345)
0.1 0.4 GO:0004743 pyruvate kinase activity(GO:0004743)
0.1 0.5 GO:0038051 glucocorticoid receptor activity(GO:0004883) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.1 0.4 GO:0031752 D5 dopamine receptor binding(GO:0031752)
0.1 0.5 GO:0060228 phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
0.0 0.4 GO:0018479 benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.0 0.4 GO:0086075 gap junction channel activity involved in cardiac conduction electrical coupling(GO:0086075)
0.0 0.4 GO:0004117 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117)
0.0 0.1 GO:0019862 IgA binding(GO:0019862)
0.0 0.1 GO:0005010 insulin-like growth factor-activated receptor activity(GO:0005010)
0.0 0.1 GO:0001181 transcription factor activity, core RNA polymerase I binding(GO:0001181)
0.0 0.2 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.0 0.1 GO:0047225 acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0047225)
0.0 0.1 GO:0070653 high-density lipoprotein particle receptor binding(GO:0070653)
0.0 0.1 GO:0032427 GBD domain binding(GO:0032427)
0.0 0.1 GO:0005128 erythropoietin receptor binding(GO:0005128)
0.0 0.4 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.0 0.8 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.3 GO:0004340 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.0 0.1 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.0 0.1 GO:0019948 SUMO activating enzyme activity(GO:0019948)
0.0 0.1 GO:0001069 regulatory region RNA binding(GO:0001069)
0.0 0.1 GO:0003883 CTP synthase activity(GO:0003883)
0.0 0.0 GO:0004716 receptor signaling protein tyrosine kinase activity(GO:0004716)
0.0 0.1 GO:0008422 beta-glucosidase activity(GO:0008422)
0.0 0.2 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.0 0.1 GO:0072590 N-acetyl-L-aspartate-L-glutamate ligase activity(GO:0072590)
0.0 0.1 GO:0050115 myosin-light-chain-phosphatase activity(GO:0050115)
0.0 0.1 GO:0047391 alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391)
0.0 1.3 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.3 GO:0022851 GABA-gated chloride ion channel activity(GO:0022851)
0.0 0.1 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.0 0.1 GO:0086062 voltage-gated sodium channel activity involved in Purkinje myocyte action potential(GO:0086062)
0.0 0.2 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.4 GO:0004526 ribonuclease P activity(GO:0004526)
0.0 0.2 GO:0034597 phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597)
0.0 0.1 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
0.0 0.1 GO:0031871 proteinase activated receptor binding(GO:0031871)
0.0 0.2 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.0 0.1 GO:0008808 cardiolipin synthase activity(GO:0008808) phosphatidyltransferase activity(GO:0030572) CDP-diacylglycerol-phosphatidylglycerol phosphatidyltransferase activity(GO:0043337)
0.0 0.1 GO:0004515 nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
0.0 0.1 GO:0035243 protein-arginine omega-N symmetric methyltransferase activity(GO:0035243)
0.0 0.2 GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.0 0.1 GO:0050119 N-acetylglucosamine deacetylase activity(GO:0050119)
0.0 0.0 GO:0090541 MIT domain binding(GO:0090541)
0.0 0.1 GO:0051373 FATZ binding(GO:0051373)
0.0 0.1 GO:0016429 tRNA (adenine) methyltransferase activity(GO:0016426) tRNA (adenine-N1-)-methyltransferase activity(GO:0016429)
0.0 0.1 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.0 GO:0019961 interferon binding(GO:0019961)
0.0 1.0 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 0.3 GO:0050786 RAGE receptor binding(GO:0050786)
0.0 0.1 GO:0004998 transferrin receptor activity(GO:0004998)
0.0 0.1 GO:0019237 centromeric DNA binding(GO:0019237)
0.0 0.1 GO:0070051 fibrinogen binding(GO:0070051)
0.0 0.4 GO:0000030 mannosyltransferase activity(GO:0000030)
0.0 0.3 GO:0005168 neurotrophin TRKA receptor binding(GO:0005168)
0.0 0.0 GO:0008520 L-ascorbate:sodium symporter activity(GO:0008520) L-ascorbic acid transporter activity(GO:0015229) sodium-dependent L-ascorbate transmembrane transporter activity(GO:0070890)
0.0 0.1 GO:0008420 CTD phosphatase activity(GO:0008420)
0.0 0.1 GO:0001165 RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165)
0.0 0.1 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.0 0.3 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.1 GO:1904929 coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway(GO:1904929)
0.0 0.1 GO:0005119 smoothened binding(GO:0005119)
0.0 0.2 GO:0005344 oxygen transporter activity(GO:0005344)
0.0 0.1 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.0 0.7 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 0.4 PID S1P S1P4 PATHWAY S1P4 pathway
0.0 0.6 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.0 0.8 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 0.4 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
0.0 0.1 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0 0.3 REACTOME SOS MEDIATED SIGNALLING Genes involved in SOS-mediated signalling
0.0 0.5 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 0.2 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation