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SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for MBD2

Z-value: 1.04

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Transcription factors associated with MBD2

Gene Symbol Gene ID Gene Info
MBD2
ENSG00000134046.7 methyl-CpG binding domain protein 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
MBD2hg19_v2_chr18_-_51750948_51751059-0.604.7e-03Click!

Activity profile of MBD2 motif

Sorted Z-values of MBD2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr19_-_14201507 1.38 ENST00000533683.2
SAMD1
sterile alpha motif domain containing 1
chr1_-_154531095 1.37 ENST00000292211.4
UBE2Q1
ubiquitin-conjugating enzyme E2Q family member 1
chr20_+_36531499 1.35 ENST00000373458.3
ENST00000373461.4
ENST00000373459.4
VSTM2L
V-set and transmembrane domain containing 2 like
chr3_-_185542817 1.25 ENST00000382199.2
IGF2BP2
insulin-like growth factor 2 mRNA binding protein 2
chr11_-_46142948 1.24 ENST00000257821.4
PHF21A
PHD finger protein 21A
chr8_-_145688231 1.21 ENST00000530374.1
CYHR1
cysteine/histidine-rich 1
chr3_-_196295437 1.19 ENST00000429115.1
WDR53
WD repeat domain 53
chr6_+_29795595 1.14 ENST00000360323.6
ENST00000376818.3
ENST00000376815.3
HLA-G
major histocompatibility complex, class I, G
chr12_+_7037461 1.09 ENST00000396684.2
ATN1
atrophin 1
chr1_-_22469459 1.07 ENST00000290167.6
WNT4
wingless-type MMTV integration site family, member 4
chr8_-_57123815 1.07 ENST00000316981.3
ENST00000423799.2
ENST00000429357.2
PLAG1
pleiomorphic adenoma gene 1
chr6_+_45389893 1.05 ENST00000371432.3
RUNX2
runt-related transcription factor 2
chr2_+_42275153 1.01 ENST00000294964.5
PKDCC
protein kinase domain containing, cytoplasmic
chr10_-_123357598 1.00 ENST00000358487.5
ENST00000369058.3
ENST00000369060.4
ENST00000359354.2
FGFR2
fibroblast growth factor receptor 2
chr3_-_185542761 1.00 ENST00000457616.2
ENST00000346192.3
IGF2BP2
insulin-like growth factor 2 mRNA binding protein 2
chr1_-_155243235 0.95 ENST00000355560.4
ENST00000368361.4
CLK2
CDC-like kinase 2
chr16_+_2059872 0.93 ENST00000567649.1
NPW
neuropeptide W
chr6_-_43596899 0.90 ENST00000307126.5
ENST00000452781.1
GTPBP2
GTP binding protein 2
chr18_+_8609402 0.89 ENST00000329286.6
RAB12
RAB12, member RAS oncogene family
chr1_-_150552006 0.89 ENST00000307940.3
ENST00000369026.2
MCL1
myeloid cell leukemia sequence 1 (BCL2-related)
chrX_+_152953505 0.88 ENST00000253122.5
SLC6A8
solute carrier family 6 (neurotransmitter transporter), member 8
chr22_+_19419425 0.87 ENST00000333130.3
MRPL40
mitochondrial ribosomal protein L40
chr5_-_176778803 0.87 ENST00000303127.7
LMAN2
lectin, mannose-binding 2
chr1_-_161008697 0.86 ENST00000318289.10
ENST00000368023.3
ENST00000368024.1
ENST00000423014.2
TSTD1
thiosulfate sulfurtransferase (rhodanese)-like domain containing 1
chr6_+_1610681 0.83 ENST00000380874.2
FOXC1
forkhead box C1
chr2_-_220408430 0.81 ENST00000243776.6
CHPF
chondroitin polymerizing factor
chr20_+_34894247 0.80 ENST00000373913.3
DLGAP4
discs, large (Drosophila) homolog-associated protein 4
chr6_+_31865552 0.78 ENST00000469372.1
ENST00000497706.1
C2
complement component 2
chr10_-_123357910 0.78 ENST00000336553.6
ENST00000457416.2
ENST00000360144.3
ENST00000369059.1
ENST00000356226.4
ENST00000351936.6
FGFR2
fibroblast growth factor receptor 2
chr1_-_6545502 0.77 ENST00000535355.1
PLEKHG5
pleckstrin homology domain containing, family G (with RhoGef domain) member 5
chr2_-_129076151 0.77 ENST00000259241.6
HS6ST1
heparan sulfate 6-O-sulfotransferase 1
chr10_+_75545329 0.75 ENST00000604729.1
ENST00000603114.1
ZSWIM8
zinc finger, SWIM-type containing 8
chr1_+_43148059 0.74 ENST00000321358.7
ENST00000332220.6
YBX1
Y box binding protein 1
chr3_-_48470838 0.74 ENST00000358459.4
ENST00000358536.4
PLXNB1
plexin B1
chr10_-_92617437 0.74 ENST00000336152.3
ENST00000277874.6
ENST00000371719.2
HTR7
5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled
chr11_+_64685026 0.73 ENST00000526559.1
PPP2R5B
protein phosphatase 2, regulatory subunit B', beta
chr3_+_184097836 0.73 ENST00000204604.1
ENST00000310236.3
CHRD
chordin
chr3_+_184279566 0.72 ENST00000330394.2
EPHB3
EPH receptor B3
chr1_+_43148625 0.72 ENST00000436427.1
YBX1
Y box binding protein 1
chr3_+_50273625 0.72 ENST00000536647.1
GNAI2
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2
chr22_+_29279552 0.72 ENST00000544604.2
ZNRF3
zinc and ring finger 3
chr10_-_105615164 0.71 ENST00000355946.2
ENST00000369774.4
SH3PXD2A
SH3 and PX domains 2A
chr11_+_67056755 0.70 ENST00000511455.2
ENST00000308440.6
ANKRD13D
ankyrin repeat domain 13 family, member D
chr7_-_139876812 0.70 ENST00000397560.2
JHDM1D
lysine (K)-specific demethylase 7A
chr13_+_27131887 0.70 ENST00000335327.5
WASF3
WAS protein family, member 3
chr10_+_75545391 0.69 ENST00000604524.1
ENST00000605216.1
ENST00000398706.2
ZSWIM8
zinc finger, SWIM-type containing 8
chr11_-_46142615 0.69 ENST00000529734.1
ENST00000323180.6
PHF21A
PHD finger protein 21A
chr3_-_48471454 0.68 ENST00000296440.6
ENST00000448774.2
PLXNB1
plexin B1
chr10_+_104404218 0.68 ENST00000302424.7
TRIM8
tripartite motif containing 8
chr17_+_68165657 0.68 ENST00000243457.3
KCNJ2
potassium inwardly-rectifying channel, subfamily J, member 2
chr7_+_40174565 0.67 ENST00000309930.5
ENST00000401647.2
ENST00000335693.4
ENST00000413931.1
ENST00000416370.1
ENST00000540834.1
C7orf10
succinylCoA:glutarate-CoA transferase
chr16_+_2022036 0.66 ENST00000568546.1
TBL3
transducin (beta)-like 3
chr11_+_67056867 0.65 ENST00000514166.1
ANKRD13D
ankyrin repeat domain 13 family, member D
chr12_+_57482665 0.65 ENST00000300131.3
NAB2
NGFI-A binding protein 2 (EGR1 binding protein 2)
chr12_+_122516626 0.64 ENST00000319080.7
MLXIP
MLX interacting protein
chr20_-_39317868 0.62 ENST00000373313.2
MAFB
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
chr2_+_5832799 0.61 ENST00000322002.3
SOX11
SRY (sex determining region Y)-box 11
chr17_+_65374075 0.61 ENST00000581322.1
PITPNC1
phosphatidylinositol transfer protein, cytoplasmic 1
chr7_-_8301869 0.61 ENST00000402384.3
ICA1
islet cell autoantigen 1, 69kDa
chr5_+_49962772 0.61 ENST00000281631.5
ENST00000513738.1
ENST00000503665.1
ENST00000514067.2
ENST00000503046.1
PARP8
poly (ADP-ribose) polymerase family, member 8
chr19_-_46148820 0.60 ENST00000587152.1
EML2
echinoderm microtubule associated protein like 2
chr13_+_27131798 0.60 ENST00000361042.4
WASF3
WAS protein family, member 3
chr1_+_6845384 0.60 ENST00000303635.7
CAMTA1
calmodulin binding transcription activator 1
chr3_-_196295468 0.60 ENST00000332629.5
ENST00000433160.1
WDR53
WD repeat domain 53
chr3_-_52001448 0.59 ENST00000461554.1
ENST00000395013.3
ENST00000428823.2
ENST00000483411.1
ENST00000461544.1
ENST00000355852.2
PCBP4
poly(rC) binding protein 4
chr12_+_57482877 0.59 ENST00000342556.6
ENST00000357680.4
NAB2
NGFI-A binding protein 2 (EGR1 binding protein 2)
chr7_-_8301682 0.59 ENST00000396675.3
ENST00000430867.1
ICA1
islet cell autoantigen 1, 69kDa
chr3_+_184097905 0.59 ENST00000450923.1
CHRD
chordin
chr16_-_51185149 0.59 ENST00000566102.1
ENST00000541611.1
SALL1
spalt-like transcription factor 1
chr7_-_8301768 0.58 ENST00000265577.7
ICA1
islet cell autoantigen 1, 69kDa
chr1_-_32801825 0.58 ENST00000329421.7
MARCKSL1
MARCKS-like 1
chr7_-_127672146 0.58 ENST00000476782.1
LRRC4
leucine rich repeat containing 4
chr12_-_124457257 0.58 ENST00000545891.1
CCDC92
coiled-coil domain containing 92
chr14_+_53019822 0.57 ENST00000321662.6
GPR137C
G protein-coupled receptor 137C
chr19_-_11373128 0.57 ENST00000294618.7
DOCK6
dedicator of cytokinesis 6
chr3_+_184098065 0.56 ENST00000348986.3
CHRD
chordin
chr19_+_56152361 0.56 ENST00000585995.1
ENST00000592996.1
ZNF581
CCDC106
zinc finger protein 581
coiled-coil domain containing 106
chr11_-_79151695 0.56 ENST00000278550.7
TENM4
teneurin transmembrane protein 4
chr19_+_56152262 0.56 ENST00000325333.5
ENST00000590190.1
ZNF580
zinc finger protein 580
chr11_-_61735029 0.56 ENST00000526640.1
FTH1
ferritin, heavy polypeptide 1
chr12_+_121078355 0.56 ENST00000316803.3
CABP1
calcium binding protein 1
chr2_+_220306745 0.56 ENST00000431523.1
ENST00000396698.1
ENST00000396695.2
SPEG
SPEG complex locus
chr3_-_113415441 0.55 ENST00000491165.1
ENST00000316407.4
KIAA2018
KIAA2018
chr19_+_4007644 0.54 ENST00000262971.2
PIAS4
protein inhibitor of activated STAT, 4
chr19_+_18496957 0.54 ENST00000252809.3
GDF15
growth differentiation factor 15
chr7_-_19157248 0.54 ENST00000242261.5
TWIST1
twist family bHLH transcription factor 1
chr1_+_6845497 0.54 ENST00000473578.1
ENST00000557126.1
CAMTA1
calmodulin binding transcription activator 1
chr9_+_135037334 0.53 ENST00000393229.3
ENST00000360670.3
ENST00000393228.4
ENST00000372179.3
NTNG2
netrin G2
chr6_+_139456226 0.53 ENST00000367658.2
HECA
headcase homolog (Drosophila)
chr1_+_167190066 0.53 ENST00000367866.2
ENST00000429375.2
ENST00000452019.1
ENST00000420254.3
ENST00000541643.3
POU2F1
POU class 2 homeobox 1
chr19_-_4124079 0.53 ENST00000394867.4
ENST00000262948.5
MAP2K2
mitogen-activated protein kinase kinase 2
chr2_+_10091783 0.52 ENST00000324883.5
GRHL1
grainyhead-like 1 (Drosophila)
chr22_+_38035459 0.52 ENST00000357436.4
SH3BP1
SH3-domain binding protein 1
chr9_-_130617029 0.52 ENST00000373203.4
ENG
endoglin
chr20_+_36531544 0.52 ENST00000448944.1
VSTM2L
V-set and transmembrane domain containing 2 like
chr19_-_36545649 0.52 ENST00000292894.1
THAP8
THAP domain containing 8
chr1_+_156698234 0.52 ENST00000368218.4
ENST00000368216.4
RRNAD1
ribosomal RNA adenine dimethylase domain containing 1
chr9_-_140115775 0.51 ENST00000391553.1
ENST00000392827.1
RNF208
ring finger protein 208
chr14_+_93799556 0.51 ENST00000256339.4
UNC79
unc-79 homolog (C. elegans)
chr17_-_27278304 0.51 ENST00000577226.1
PHF12
PHD finger protein 12
chr9_-_135996537 0.51 ENST00000372050.3
ENST00000372047.3
RALGDS
ral guanine nucleotide dissociation stimulator
chr11_+_64851729 0.51 ENST00000526791.1
ENST00000526945.1
ZFPL1
zinc finger protein-like 1
chr11_-_62369291 0.51 ENST00000278823.2
MTA2
metastasis associated 1 family, member 2
chr10_-_92617671 0.50 ENST00000371721.3
HTR7
5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled
chr11_+_43380459 0.50 ENST00000299240.6
ENST00000039989.4
TTC17
tetratricopeptide repeat domain 17
chr1_-_6546001 0.50 ENST00000400913.1
PLEKHG5
pleckstrin homology domain containing, family G (with RhoGef domain) member 5
chr5_-_176778523 0.50 ENST00000513877.1
ENST00000515209.1
ENST00000514458.1
ENST00000502560.1
LMAN2
lectin, mannose-binding 2
chr11_+_67033881 0.49 ENST00000308595.5
ENST00000526285.1
ADRBK1
adrenergic, beta, receptor kinase 1
chr2_+_10091815 0.49 ENST00000324907.9
GRHL1
grainyhead-like 1 (Drosophila)
chr19_-_17137625 0.49 ENST00000443236.1
ENST00000388925.4
CPAMD8
C3 and PZP-like, alpha-2-macroglobulin domain containing 8
chr18_+_34409069 0.48 ENST00000543923.1
ENST00000280020.5
ENST00000435985.2
ENST00000592521.1
ENST00000587139.1
KIAA1328
KIAA1328
chr1_+_3689325 0.48 ENST00000444870.2
ENST00000452264.1
SMIM1
small integral membrane protein 1 (Vel blood group)
chr12_-_50222187 0.48 ENST00000335999.6
NCKAP5L
NCK-associated protein 5-like
chr2_+_220299547 0.48 ENST00000312358.7
SPEG
SPEG complex locus
chr16_-_2059797 0.48 ENST00000563630.1
ZNF598
zinc finger protein 598
chr7_-_129251459 0.48 ENST00000608694.1
RP11-448A19.1
RP11-448A19.1
chr5_-_180236811 0.48 ENST00000446023.2
MGAT1
mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
chr9_-_130616915 0.47 ENST00000344849.3
ENG
endoglin
chr13_+_98795664 0.47 ENST00000376581.5
FARP1
FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)
chr19_+_6739662 0.47 ENST00000313285.8
ENST00000313244.9
ENST00000596758.1
TRIP10
thyroid hormone receptor interactor 10
chrX_-_53350522 0.46 ENST00000396435.3
ENST00000375368.5
IQSEC2
IQ motif and Sec7 domain 2
chr1_+_4714792 0.46 ENST00000378190.3
AJAP1
adherens junctions associated protein 1
chr6_+_2245982 0.45 ENST00000530346.1
ENST00000524770.1
ENST00000532124.1
ENST00000531092.1
ENST00000456943.2
ENST00000529893.1
GMDS-AS1
GMDS antisense RNA 1 (head to head)
chr1_+_6845578 0.45 ENST00000467404.2
ENST00000439411.2
CAMTA1
calmodulin binding transcription activator 1
chr14_-_21566731 0.44 ENST00000360947.3
ZNF219
zinc finger protein 219
chr16_-_28074822 0.44 ENST00000395724.3
ENST00000380898.2
ENST00000447459.2
GSG1L
GSG1-like
chr19_-_46476791 0.44 ENST00000263257.5
NOVA2
neuro-oncological ventral antigen 2
chr14_+_103851712 0.44 ENST00000440884.3
ENST00000416682.2
ENST00000429436.2
ENST00000303622.9
MARK3
MAP/microtubule affinity-regulating kinase 3
chr9_+_124413873 0.44 ENST00000408936.3
DAB2IP
DAB2 interacting protein
chr12_-_29936731 0.44 ENST00000552618.1
ENST00000539277.1
ENST00000551659.1
TMTC1
transmembrane and tetratricopeptide repeat containing 1
chr11_+_67055986 0.43 ENST00000447274.2
ANKRD13D
ankyrin repeat domain 13 family, member D
chr11_-_61734599 0.43 ENST00000532601.1
FTH1
ferritin, heavy polypeptide 1
chr7_-_127671674 0.43 ENST00000478726.1
LRRC4
leucine rich repeat containing 4
chr5_-_176900610 0.43 ENST00000477391.2
ENST00000393565.1
ENST00000309007.5
DBN1
drebrin 1
chr16_+_1823208 0.43 ENST00000568449.1
ENST00000307394.7
EME2
essential meiotic structure-specific endonuclease subunit 2
chr16_-_89787360 0.42 ENST00000389386.3
VPS9D1
VPS9 domain containing 1
chr10_-_25012597 0.42 ENST00000396432.2
ARHGAP21
Rho GTPase activating protein 21
chr19_-_4066890 0.42 ENST00000322357.4
ZBTB7A
zinc finger and BTB domain containing 7A
chr20_-_60640866 0.42 ENST00000252996.4
TAF4
TAF4 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 135kDa
chr18_-_51750948 0.42 ENST00000583046.1
ENST00000398398.2
MBD2
methyl-CpG binding domain protein 2
chr17_+_65821780 0.41 ENST00000321892.4
ENST00000335221.5
ENST00000306378.6
BPTF
bromodomain PHD finger transcription factor
chr19_+_50354462 0.41 ENST00000601675.1
PTOV1
prostate tumor overexpressed 1
chr11_-_62368696 0.41 ENST00000527204.1
MTA2
metastasis associated 1 family, member 2
chr1_+_11539204 0.41 ENST00000294484.6
ENST00000389575.3
PTCHD2
patched domain containing 2
chr1_-_27693349 0.41 ENST00000374040.3
ENST00000357582.2
ENST00000493901.1
MAP3K6
mitogen-activated protein kinase kinase kinase 6
chr2_+_113033164 0.41 ENST00000409871.1
ENST00000343936.4
ZC3H6
zinc finger CCCH-type containing 6
chr19_+_50353944 0.40 ENST00000594151.1
ENST00000600603.1
ENST00000601638.1
ENST00000221557.9
PTOV1
prostate tumor overexpressed 1
chr12_-_124457371 0.40 ENST00000238156.3
ENST00000545037.1
CCDC92
coiled-coil domain containing 92
chr19_+_50354430 0.40 ENST00000599732.1
PTOV1
prostate tumor overexpressed 1
chr22_-_20792089 0.40 ENST00000405555.3
ENST00000266214.5
SCARF2
scavenger receptor class F, member 2
chr1_+_28995231 0.40 ENST00000373816.1
GMEB1
glucocorticoid modulatory element binding protein 1
chr11_-_76381781 0.40 ENST00000260061.5
ENST00000404995.1
LRRC32
leucine rich repeat containing 32
chr1_+_82266053 0.39 ENST00000370715.1
ENST00000370713.1
ENST00000319517.6
ENST00000370717.2
ENST00000394879.1
ENST00000271029.4
ENST00000335786.5
LPHN2
latrophilin 2
chr6_-_42981651 0.39 ENST00000244711.3
MEA1
male-enhanced antigen 1
chr12_+_6875519 0.39 ENST00000389462.4
ENST00000540874.1
ENST00000309083.6
PTMS
parathymosin
chr14_+_21538517 0.38 ENST00000298693.3
ARHGEF40
Rho guanine nucleotide exchange factor (GEF) 40
chr20_-_590944 0.38 ENST00000246080.3
TCF15
transcription factor 15 (basic helix-loop-helix)
chr2_+_181845298 0.38 ENST00000410062.4
UBE2E3
ubiquitin-conjugating enzyme E2E 3
chr3_+_238969 0.38 ENST00000421198.1
CHL1
cell adhesion molecule L1-like
chr19_-_17445613 0.38 ENST00000159087.4
ANO8
anoctamin 8
chr8_+_30241995 0.37 ENST00000397323.4
ENST00000339877.4
ENST00000320203.4
ENST00000287771.5
RBPMS
RNA binding protein with multiple splicing
chr17_-_27949911 0.37 ENST00000492276.2
ENST00000345068.5
ENST00000584602.1
CORO6
coronin 6
chr17_+_54671047 0.37 ENST00000332822.4
NOG
noggin
chr1_-_54872059 0.37 ENST00000371320.3
SSBP3
single stranded DNA binding protein 3
chr11_-_64545941 0.37 ENST00000377387.1
SF1
splicing factor 1
chr11_-_89224638 0.37 ENST00000535633.1
ENST00000263317.4
NOX4
NADPH oxidase 4
chr8_-_119124045 0.37 ENST00000378204.2
EXT1
exostosin glycosyltransferase 1
chr9_+_132597722 0.37 ENST00000372429.3
ENST00000315480.4
ENST00000358355.1
USP20
ubiquitin specific peptidase 20
chrX_-_152939252 0.37 ENST00000340888.3
PNCK
pregnancy up-regulated nonubiquitous CaM kinase
chr8_+_144349606 0.36 ENST00000521682.1
ENST00000340042.1
GLI4
GLI family zinc finger 4
chr2_+_54198210 0.36 ENST00000607452.1
ENST00000422521.2
ACYP2
acylphosphatase 2, muscle type
chr20_+_20348740 0.36 ENST00000310227.1
INSM1
insulinoma-associated 1
chr1_+_27561104 0.36 ENST00000361771.3
WDTC1
WD and tetratricopeptide repeats 1
chr19_-_16653226 0.36 ENST00000198939.6
CHERP
calcium homeostasis endoplasmic reticulum protein
chr9_+_140772226 0.36 ENST00000277551.2
ENST00000371372.1
ENST00000277549.5
ENST00000371363.1
ENST00000371357.1
ENST00000371355.4
CACNA1B
calcium channel, voltage-dependent, N type, alpha 1B subunit
chr12_+_132195617 0.36 ENST00000261674.4
ENST00000535236.1
ENST00000541286.1
SFSWAP
splicing factor, suppressor of white-apricot homolog (Drosophila)
chr1_-_32229934 0.36 ENST00000398542.1
BAI2
brain-specific angiogenesis inhibitor 2
chr10_+_129845823 0.36 ENST00000306042.5
PTPRE
protein tyrosine phosphatase, receptor type, E
chr19_+_36208877 0.36 ENST00000420124.1
ENST00000222270.7
ENST00000341701.1
KMT2B
Histone-lysine N-methyltransferase 2B
chr16_+_29817841 0.36 ENST00000322945.6
ENST00000562337.1
ENST00000566906.2
ENST00000563402.1
ENST00000219782.6
MAZ
MYC-associated zinc finger protein (purine-binding transcription factor)
chr1_+_27561007 0.35 ENST00000319394.3
WDTC1
WD and tetratricopeptide repeats 1
chr16_-_2059748 0.35 ENST00000562103.1
ENST00000431526.1
ZNF598
zinc finger protein 598
chr3_-_133969437 0.35 ENST00000460933.1
ENST00000296084.4
RYK
receptor-like tyrosine kinase
chr11_-_64684672 0.35 ENST00000377264.3
ENST00000421419.2
ATG2A
autophagy related 2A
chr19_-_49622348 0.35 ENST00000408991.2
C19orf73
chromosome 19 open reading frame 73
chr1_+_156252708 0.35 ENST00000295694.5
ENST00000357501.2
TMEM79
transmembrane protein 79
chr18_-_53255766 0.35 ENST00000566286.1
ENST00000564999.1
ENST00000566279.1
ENST00000354452.3
ENST00000356073.4
TCF4
transcription factor 4
chr17_-_7142725 0.35 ENST00000571362.1
ENST00000576955.1
ENST00000320316.3
PHF23
PHD finger protein 23
chr2_+_220408724 0.34 ENST00000421791.1
ENST00000373883.3
ENST00000451952.1
TMEM198
transmembrane protein 198
chr16_+_89787393 0.34 ENST00000289816.5
ENST00000568064.1
ZNF276
zinc finger protein 276
chr7_-_558876 0.34 ENST00000354513.5
ENST00000402802.3
PDGFA
platelet-derived growth factor alpha polypeptide
chr16_-_30022293 0.34 ENST00000565273.1
ENST00000567332.2
ENST00000350119.4
DOC2A
double C2-like domains, alpha
chr1_+_156698743 0.34 ENST00000524343.1
RRNAD1
ribosomal RNA adenine dimethylase domain containing 1
chr1_-_115053781 0.34 ENST00000358465.2
ENST00000369543.2
TRIM33
tripartite motif containing 33
chr1_-_32229523 0.34 ENST00000398547.1
ENST00000373655.2
ENST00000373658.3
ENST00000257070.4
BAI2
brain-specific angiogenesis inhibitor 2
chr3_+_49591881 0.34 ENST00000296452.4
BSN
bassoon presynaptic cytomatrix protein
chr1_+_156698708 0.34 ENST00000519086.1
RRNAD1
ribosomal RNA adenine dimethylase domain containing 1
chr3_-_183979251 0.34 ENST00000296238.3
CAMK2N2
calcium/calmodulin-dependent protein kinase II inhibitor 2
chr14_-_62162541 0.34 ENST00000557544.1
HIF1A-AS1
HIF1A antisense RNA 1
chr14_+_105886150 0.33 ENST00000331320.7
ENST00000406191.1
MTA1
metastasis associated 1

Network of associatons between targets according to the STRING database.

First level regulatory network of MBD2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.9 GO:0021919 BMP signaling pathway involved in spinal cord dorsal/ventral patterning(GO:0021919)
0.6 1.8 GO:0060915 fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow(GO:0035602) fibroblast growth factor receptor signaling pathway involved in hemopoiesis(GO:0035603) fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow(GO:0035604) fibroblast growth factor receptor signaling pathway involved in mammary gland specification(GO:0060595) mammary gland bud formation(GO:0060615) branch elongation involved in salivary gland morphogenesis(GO:0060667) mesenchymal cell differentiation involved in lung development(GO:0060915)
0.4 1.2 GO:0007198 adenylate cyclase-inhibiting serotonin receptor signaling pathway(GO:0007198)
0.4 1.1 GO:0061184 thyroid-stimulating hormone-secreting cell differentiation(GO:0060129) positive regulation of dermatome development(GO:0061184) renal vesicle induction(GO:0072034) regulation of testosterone biosynthetic process(GO:2000224)
0.3 1.0 GO:0001300 chronological cell aging(GO:0001300)
0.3 0.9 GO:0015881 creatine transport(GO:0015881) creatine transmembrane transport(GO:1902598)
0.3 0.8 GO:1902256 apoptotic process involved in outflow tract morphogenesis(GO:0003275) regulation of apoptotic process involved in outflow tract morphogenesis(GO:1902256)
0.2 1.4 GO:1900220 semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220)
0.2 0.8 GO:0072344 rescue of stalled ribosome(GO:0072344)
0.2 1.2 GO:0016480 negative regulation of transcription from RNA polymerase III promoter(GO:0016480)
0.2 0.6 GO:0035283 rhombomere 5 development(GO:0021571) central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.2 0.6 GO:0061386 closure of optic fissure(GO:0061386)
0.2 1.2 GO:1903378 positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903378)
0.2 0.6 GO:0032289 central nervous system myelin formation(GO:0032289)
0.2 0.5 GO:2000276 negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359) negative regulation of oxidative phosphorylation uncoupler activity(GO:2000276)
0.2 1.1 GO:0002767 immune response-inhibiting cell surface receptor signaling pathway(GO:0002767)
0.1 1.2 GO:0070317 negative regulation of G0 to G1 transition(GO:0070317)
0.1 0.7 GO:2000051 Wnt receptor catabolic process(GO:0038018) negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
0.1 1.1 GO:0006880 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.1 0.7 GO:0090076 relaxation of skeletal muscle(GO:0090076)
0.1 1.5 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.1 0.8 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.1 0.4 GO:0071629 cytoplasm-associated proteasomal ubiquitin-dependent protein catabolic process(GO:0071629)
0.1 0.4 GO:0097065 anterior head development(GO:0097065) regulation of anterior head development(GO:2000742) positive regulation of anterior head development(GO:2000744)
0.1 0.8 GO:0021553 olfactory nerve development(GO:0021553)
0.1 0.3 GO:0097535 lymphoid lineage cell migration(GO:0097534) lymphoid lineage cell migration into thymus(GO:0097535)
0.1 1.0 GO:0042997 negative regulation of Golgi to plasma membrane protein transport(GO:0042997)
0.1 0.7 GO:0072674 multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675)
0.1 0.5 GO:0021623 optic cup structural organization(GO:0003409) oculomotor nerve morphogenesis(GO:0021622) oculomotor nerve formation(GO:0021623)
0.1 1.4 GO:0070459 prolactin secretion(GO:0070459)
0.1 0.2 GO:0021849 neuroblast division in subventricular zone(GO:0021849)
0.1 0.5 GO:1902174 positive regulation of keratinocyte apoptotic process(GO:1902174)
0.1 0.4 GO:0003357 noradrenergic neuron differentiation(GO:0003357)
0.1 0.5 GO:0036518 chemorepulsion of dopaminergic neuron axon(GO:0036518)
0.1 0.6 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.1 1.0 GO:0002051 osteoblast fate commitment(GO:0002051)
0.1 0.5 GO:0051490 negative regulation of filopodium assembly(GO:0051490)
0.1 0.4 GO:1901097 negative regulation of autophagosome maturation(GO:1901097)
0.1 0.5 GO:0030860 regulation of polarized epithelial cell differentiation(GO:0030860)
0.1 0.5 GO:0090170 regulation of Golgi inheritance(GO:0090170)
0.1 0.4 GO:2000313 fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060825) regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000313)
0.1 0.3 GO:1903719 regulation of I-kappaB phosphorylation(GO:1903719) positive regulation of I-kappaB phosphorylation(GO:1903721)
0.1 0.7 GO:0051533 positive regulation of NFAT protein import into nucleus(GO:0051533)
0.1 0.4 GO:0010643 cell communication by chemical coupling(GO:0010643)
0.1 0.2 GO:0072356 chromosome passenger complex localization to kinetochore(GO:0072356)
0.1 0.2 GO:0035526 retrograde transport, plasma membrane to Golgi(GO:0035526)
0.1 1.1 GO:0060252 positive regulation of glial cell proliferation(GO:0060252)
0.1 0.2 GO:0061357 positive regulation of Wnt protein secretion(GO:0061357)
0.1 0.4 GO:0033159 negative regulation of protein import into nucleus, translocation(GO:0033159)
0.1 0.2 GO:1904117 response to vasopressin(GO:1904116) cellular response to vasopressin(GO:1904117)
0.1 0.3 GO:0042335 cuticle development(GO:0042335)
0.1 0.3 GO:0010512 negative regulation of phosphatidylinositol biosynthetic process(GO:0010512)
0.1 0.8 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.1 0.4 GO:0061458 reproductive system development(GO:0061458)
0.1 0.3 GO:0046726 positive regulation by virus of viral protein levels in host cell(GO:0046726)
0.1 0.3 GO:1902499 positive regulation of protein autoubiquitination(GO:1902499)
0.1 0.3 GO:0061188 negative regulation of chromatin silencing at rDNA(GO:0061188)
0.1 0.3 GO:0090258 negative regulation of mitochondrial fission(GO:0090258)
0.1 1.0 GO:0002934 desmosome organization(GO:0002934)
0.1 0.5 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.1 0.5 GO:0006049 UDP-N-acetylglucosamine catabolic process(GO:0006049)
0.1 0.2 GO:0035854 regulation of primitive erythrocyte differentiation(GO:0010725) eosinophil fate commitment(GO:0035854)
0.0 0.5 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
0.0 1.5 GO:0031643 positive regulation of myelination(GO:0031643)
0.0 0.6 GO:0010968 regulation of microtubule nucleation(GO:0010968)
0.0 0.8 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
0.0 1.2 GO:0031167 rRNA methylation(GO:0031167)
0.0 0.3 GO:1901668 regulation of superoxide dismutase activity(GO:1901668)
0.0 0.1 GO:0070634 transepithelial ammonium transport(GO:0070634)
0.0 0.2 GO:0019230 proprioception(GO:0019230)
0.0 0.2 GO:0042631 cellular response to water deprivation(GO:0042631)
0.0 0.8 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)
0.0 0.2 GO:0098582 innate vocalization behavior(GO:0098582)
0.0 1.0 GO:0097119 postsynaptic density protein 95 clustering(GO:0097119)
0.0 0.3 GO:2000035 regulation of stem cell division(GO:2000035)
0.0 0.1 GO:0002519 natural killer cell tolerance induction(GO:0002519) regulation of tolerance induction dependent upon immune response(GO:0002652) negative regulation of response to tumor cell(GO:0002835) negative regulation of immune response to tumor cell(GO:0002838) negative regulation of natural killer cell mediated immune response to tumor cell(GO:0002856) negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002859)
0.0 0.1 GO:0006091 generation of precursor metabolites and energy(GO:0006091)
0.0 0.1 GO:0048007 synaptic vesicle recycling via endosome(GO:0036466) antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003) antigen processing and presentation, exogenous lipid antigen via MHC class Ib(GO:0048007)
0.0 0.2 GO:0072560 glandular epithelial cell maturation(GO:0002071) type B pancreatic cell maturation(GO:0072560)
0.0 0.3 GO:0035726 common myeloid progenitor cell proliferation(GO:0035726)
0.0 0.1 GO:0090271 positive regulation of fibroblast growth factor production(GO:0090271)
0.0 1.2 GO:0008285 negative regulation of cell proliferation(GO:0008285)
0.0 0.7 GO:0001973 adenosine receptor signaling pathway(GO:0001973)
0.0 0.4 GO:0045198 establishment of epithelial cell apical/basal polarity(GO:0045198)
0.0 0.1 GO:0045212 negative regulation of synaptic transmission, cholinergic(GO:0032223) neurotransmitter receptor biosynthetic process(GO:0045212)
0.0 0.3 GO:0006572 tyrosine catabolic process(GO:0006572)
0.0 0.1 GO:1990697 protein depalmitoleylation(GO:1990697)
0.0 0.3 GO:0046952 ketone body catabolic process(GO:0046952)
0.0 0.6 GO:0008284 positive regulation of cell proliferation(GO:0008284)
0.0 0.1 GO:1902725 negative regulation of satellite cell differentiation(GO:1902725)
0.0 0.0 GO:0021913 regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913)
0.0 0.2 GO:0051835 positive regulation of synapse structural plasticity(GO:0051835)
0.0 0.1 GO:0042137 sequestering of neurotransmitter(GO:0042137)
0.0 0.3 GO:0070544 histone H3-K36 demethylation(GO:0070544)
0.0 0.1 GO:0072268 pattern specification involved in metanephros development(GO:0072268)
0.0 0.7 GO:0045717 negative regulation of fatty acid biosynthetic process(GO:0045717)
0.0 0.6 GO:0048149 behavioral response to ethanol(GO:0048149)
0.0 0.1 GO:0032470 positive regulation of endoplasmic reticulum calcium ion concentration(GO:0032470) calcium ion transport from cytosol to endoplasmic reticulum(GO:1903515)
0.0 0.7 GO:0046597 negative regulation of viral entry into host cell(GO:0046597) negative regulation of viral release from host cell(GO:1902187)
0.0 0.6 GO:0080182 histone H3-K4 trimethylation(GO:0080182)
0.0 1.4 GO:0035767 endothelial cell chemotaxis(GO:0035767)
0.0 0.1 GO:0021718 superior olivary nucleus development(GO:0021718) superior olivary nucleus maturation(GO:0021722)
0.0 1.0 GO:0042554 superoxide anion generation(GO:0042554)
0.0 0.4 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.0 0.4 GO:0000183 chromatin silencing at rDNA(GO:0000183)
0.0 0.2 GO:0046985 positive regulation of hemoglobin biosynthetic process(GO:0046985)
0.0 0.7 GO:0022038 corpus callosum development(GO:0022038)
0.0 1.8 GO:0050885 neuromuscular process controlling balance(GO:0050885)
0.0 0.2 GO:0060174 limb bud formation(GO:0060174)
0.0 0.2 GO:0006616 SRP-dependent cotranslational protein targeting to membrane, translocation(GO:0006616)
0.0 0.4 GO:0007252 I-kappaB phosphorylation(GO:0007252)
0.0 0.3 GO:2000623 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.0 1.4 GO:0050766 positive regulation of phagocytosis(GO:0050766)
0.0 0.4 GO:0000712 resolution of meiotic recombination intermediates(GO:0000712)
0.0 0.5 GO:0035640 exploration behavior(GO:0035640)
0.0 0.2 GO:0051013 microtubule severing(GO:0051013)
0.0 0.6 GO:0032757 positive regulation of interleukin-8 production(GO:0032757)
0.0 0.4 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.0 0.2 GO:0030213 hyaluronan biosynthetic process(GO:0030213)
0.0 0.2 GO:1900122 positive regulation of receptor binding(GO:1900122)
0.0 0.5 GO:1901741 positive regulation of myoblast fusion(GO:1901741)
0.0 0.1 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.0 0.1 GO:0090118 receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport(GO:0090118)
0.0 0.2 GO:2000467 positive regulation of glycogen (starch) synthase activity(GO:2000467)
0.0 0.3 GO:0070936 protein K48-linked ubiquitination(GO:0070936)
0.0 0.1 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.0 2.1 GO:0042035 regulation of cytokine biosynthetic process(GO:0042035)
0.0 0.1 GO:1901421 positive regulation of response to alcohol(GO:1901421)
0.0 0.1 GO:0048170 positive regulation of long-term neuronal synaptic plasticity(GO:0048170)
0.0 0.2 GO:0001865 NK T cell differentiation(GO:0001865)
0.0 0.1 GO:0051481 negative regulation of cytosolic calcium ion concentration(GO:0051481)
0.0 0.1 GO:0030263 apoptotic chromosome condensation(GO:0030263)
0.0 0.0 GO:0007228 positive regulation of hh target transcription factor activity(GO:0007228)
0.0 0.4 GO:0001505 regulation of neurotransmitter levels(GO:0001505)
0.0 0.2 GO:0090026 positive regulation of monocyte chemotaxis(GO:0090026)
0.0 0.3 GO:0098703 calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035)
0.0 0.1 GO:2000382 positive regulation of mesoderm development(GO:2000382)
0.0 0.5 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.0 0.7 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.0 0.1 GO:1904100 regulation of protein O-linked glycosylation(GO:1904098) positive regulation of protein O-linked glycosylation(GO:1904100)
0.0 0.9 GO:0010762 regulation of fibroblast migration(GO:0010762)
0.0 0.1 GO:0032927 positive regulation of activin receptor signaling pathway(GO:0032927)
0.0 0.3 GO:0031507 heterochromatin assembly(GO:0031507)
0.0 0.2 GO:1900452 regulation of long term synaptic depression(GO:1900452)
0.0 0.1 GO:0048295 positive regulation of isotype switching to IgE isotypes(GO:0048295)
0.0 0.3 GO:2000052 positive regulation of non-canonical Wnt signaling pathway(GO:2000052)
0.0 0.0 GO:0003162 atrioventricular node development(GO:0003162) cardiac septum cell differentiation(GO:0003292) atrioventricular node cell differentiation(GO:0060922) atrioventricular node cell development(GO:0060928)
0.0 0.9 GO:0008333 endosome to lysosome transport(GO:0008333)
0.0 0.1 GO:0051933 amino acid neurotransmitter reuptake(GO:0051933) glutamate reuptake(GO:0051935)
0.0 0.3 GO:0007216 G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.0 0.7 GO:0046627 negative regulation of insulin receptor signaling pathway(GO:0046627)
0.0 0.1 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.0 0.3 GO:0033182 regulation of histone ubiquitination(GO:0033182)
0.0 0.4 GO:0044804 nucleophagy(GO:0044804)
0.0 0.2 GO:0039702 viral budding via host ESCRT complex(GO:0039702)
0.0 0.5 GO:0045599 negative regulation of fat cell differentiation(GO:0045599)
0.0 0.1 GO:0060088 auditory receptor cell stereocilium organization(GO:0060088)
0.0 0.2 GO:0007030 Golgi organization(GO:0007030)
0.0 0.2 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0072563 endothelial microparticle(GO:0072563)
0.3 1.1 GO:0008043 intracellular ferritin complex(GO:0008043) ferritin complex(GO:0070288)
0.1 1.5 GO:0071204 histone pre-mRNA 3'end processing complex(GO:0071204)
0.1 0.4 GO:1990032 parallel fiber(GO:1990032)
0.1 0.7 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.1 1.1 GO:0042612 MHC class I protein complex(GO:0042612)
0.1 1.4 GO:0002116 semaphorin receptor complex(GO:0002116)
0.1 0.5 GO:0044214 spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717)
0.1 0.3 GO:0031372 UBC13-MMS2 complex(GO:0031372)
0.1 0.4 GO:0048476 Holliday junction resolvase complex(GO:0048476)
0.1 0.2 GO:1990742 microvesicle(GO:1990742)
0.1 0.5 GO:0071203 WASH complex(GO:0071203)
0.1 0.3 GO:1990730 VCP-NSFL1C complex(GO:1990730)
0.1 1.0 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 0.2 GO:0098592 cytoplasmic side of apical plasma membrane(GO:0098592)
0.0 0.3 GO:0045298 tubulin complex(GO:0045298)
0.0 0.3 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.0 0.1 GO:0008623 CHRAC(GO:0008623)
0.0 0.2 GO:0016938 kinesin I complex(GO:0016938)
0.0 0.3 GO:1990130 Iml1 complex(GO:1990130)
0.0 1.5 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 0.2 GO:0034667 integrin alpha3-beta1 complex(GO:0034667)
0.0 0.7 GO:0033276 transcription factor TFTC complex(GO:0033276)
0.0 0.2 GO:0061617 MICOS complex(GO:0061617)
0.0 2.4 GO:0099501 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 0.4 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0 0.1 GO:0097058 CRLF-CLCF1 complex(GO:0097058) CNTFR-CLCF1 complex(GO:0097059)
0.0 0.5 GO:0098563 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 0.3 GO:0005677 chromatin silencing complex(GO:0005677)
0.0 0.3 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 0.1 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.0 0.6 GO:0005685 U1 snRNP(GO:0005685)
0.0 0.1 GO:0070083 clathrin-sculpted monoamine transport vesicle(GO:0070081) clathrin-sculpted monoamine transport vesicle membrane(GO:0070083)
0.0 0.5 GO:0005845 mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518)
0.0 0.1 GO:0042272 nuclear RNA export factor complex(GO:0042272)
0.0 1.9 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0 0.2 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.0 0.4 GO:0000346 transcription export complex(GO:0000346)
0.0 0.2 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 0.5 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.4 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.0 0.1 GO:0005726 perichromatin fibrils(GO:0005726)
0.0 0.1 GO:0061574 ASAP complex(GO:0061574)
0.0 0.7 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.1 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.0 0.4 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.9 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.2 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 0.9 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 0.7 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.0 0.6 GO:0005720 nuclear heterochromatin(GO:0005720)
0.0 0.7 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 0.2 GO:1990023 mitotic spindle midzone(GO:1990023)
0.0 0.2 GO:0000813 ESCRT I complex(GO:0000813)
0.0 1.4 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 0.4 GO:0005921 gap junction(GO:0005921)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:0005308 creatine transmembrane transporter activity(GO:0005308)
0.2 1.2 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.2 0.8 GO:0017095 heparan sulfate 6-O-sulfotransferase activity(GO:0017095)
0.2 1.9 GO:0045545 syndecan binding(GO:0045545)
0.1 1.8 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.1 0.5 GO:0045131 pre-mRNA branch point binding(GO:0045131)
0.1 0.7 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.1 1.2 GO:0051378 amine binding(GO:0043176) serotonin binding(GO:0051378)
0.1 1.0 GO:0005534 galactose binding(GO:0005534)
0.1 0.3 GO:0047696 beta-adrenergic receptor kinase activity(GO:0047696)
0.1 0.3 GO:0008427 calcium-dependent protein kinase inhibitor activity(GO:0008427)
0.1 0.3 GO:0015275 stretch-activated, cation-selective, calcium channel activity(GO:0015275)
0.1 0.9 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.1 1.1 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.1 0.6 GO:0035614 snRNA stem-loop binding(GO:0035614)
0.1 0.3 GO:0099609 microtubule lateral binding(GO:0099609)
0.1 1.8 GO:0017154 semaphorin receptor activity(GO:0017154)
0.1 0.4 GO:0050509 N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity(GO:0050509)
0.1 1.0 GO:0019826 oxygen sensor activity(GO:0019826)
0.1 0.3 GO:0008260 3-oxoacid CoA-transferase activity(GO:0008260)
0.1 0.9 GO:0008525 phosphatidylcholine transporter activity(GO:0008525)
0.1 0.3 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.1 1.3 GO:0005537 mannose binding(GO:0005537)
0.1 0.9 GO:0015266 protein channel activity(GO:0015266)
0.1 0.4 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.1 0.4 GO:0003998 acylphosphatase activity(GO:0003998)
0.1 0.5 GO:0061665 SUMO ligase activity(GO:0061665)
0.1 0.5 GO:1904929 coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway(GO:1904929)
0.1 0.6 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.1 0.5 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.1 0.4 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.0 1.1 GO:0048018 receptor agonist activity(GO:0048018)
0.0 2.2 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.0 0.4 GO:0003696 satellite DNA binding(GO:0003696)
0.0 0.1 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.4 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0 0.2 GO:0050815 phosphoserine binding(GO:0050815)
0.0 0.7 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 0.2 GO:0032184 SUMO polymer binding(GO:0032184)
0.0 0.2 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.0 0.4 GO:0004969 histamine receptor activity(GO:0004969)
0.0 0.3 GO:0050816 phosphothreonine binding(GO:0050816)
0.0 0.3 GO:0050733 RS domain binding(GO:0050733)
0.0 0.3 GO:0008174 mRNA methyltransferase activity(GO:0008174)
0.0 0.4 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.0 0.1 GO:1990699 palmitoleyl hydrolase activity(GO:1990699)
0.0 0.8 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 0.5 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 0.2 GO:0036132 13-prostaglandin reductase activity(GO:0036132) 15-oxoprostaglandin 13-oxidase activity(GO:0047522)
0.0 0.1 GO:0034046 poly(G) binding(GO:0034046)
0.0 1.2 GO:0042605 peptide antigen binding(GO:0042605)
0.0 0.4 GO:0047134 protein-disulfide reductase activity(GO:0047134)
0.0 2.1 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.0 0.1 GO:0031775 lutropin-choriogonadotropic hormone receptor binding(GO:0031775) calcium-transporting ATPase activity involved in regulation of cardiac muscle cell membrane potential(GO:0086039)
0.0 0.1 GO:0016520 growth hormone-releasing hormone receptor activity(GO:0016520)
0.0 2.6 GO:0004407 histone deacetylase activity(GO:0004407)
0.0 0.1 GO:0003990 acetylcholinesterase activity(GO:0003990)
0.0 0.1 GO:0016534 cyclin-dependent protein kinase 5 activator activity(GO:0016534)
0.0 0.9 GO:0008301 DNA binding, bending(GO:0008301)
0.0 0.4 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.0 0.7 GO:0005003 ephrin receptor activity(GO:0005003)
0.0 0.1 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.0 0.4 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 0.1 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.0 1.0 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.9 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.0 0.1 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.0 1.2 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 0.8 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 1.9 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0 0.8 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.7 GO:0019198 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.2 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 0.3 GO:0008494 translation activator activity(GO:0008494)
0.0 0.3 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.2 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.1 GO:0034056 estrogen response element binding(GO:0034056)
0.0 0.7 GO:0030515 snoRNA binding(GO:0030515)
0.0 0.3 GO:0070410 co-SMAD binding(GO:0070410)
0.0 0.4 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 0.3 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.0 0.3 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 0.4 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.4 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 0.5 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.2 GO:0035497 cAMP response element binding(GO:0035497)
0.0 1.6 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.0 0.1 GO:0061133 endopeptidase activator activity(GO:0061133)
0.0 0.1 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0 0.1 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.0 0.2 GO:0043225 anion transmembrane-transporting ATPase activity(GO:0043225)
0.0 0.4 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.0 0.2 GO:0043559 insulin binding(GO:0043559)
0.0 0.4 GO:0035035 histone acetyltransferase binding(GO:0035035)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 1.6 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.0 0.4 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 1.8 PID PTP1B PATHWAY Signaling events mediated by PTP1B
0.0 2.3 PID FGF PATHWAY FGF signaling pathway
0.0 0.5 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 0.4 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 0.8 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 0.4 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 0.8 PID BMP PATHWAY BMP receptor signaling
0.0 0.3 PID IFNG PATHWAY IFN-gamma pathway
0.0 0.6 PID MYC PATHWAY C-MYC pathway
0.0 0.7 PID EPHB FWD PATHWAY EPHB forward signaling
0.0 0.5 PID REELIN PATHWAY Reelin signaling pathway
0.0 0.8 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.2 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.1 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.1 1.9 REACTOME FGFR2C LIGAND BINDING AND ACTIVATION Genes involved in FGFR2c ligand binding and activation
0.1 1.2 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.1 0.4 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.0 0.4 REACTOME ACTIVATION OF NF KAPPAB IN B CELLS Genes involved in Activation of NF-kappaB in B Cells
0.0 1.2 REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY Genes involved in Adenylate cyclase inhibitory pathway
0.0 0.3 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.0 0.5 REACTOME RAF MAP KINASE CASCADE Genes involved in RAF/MAP kinase cascade
0.0 0.8 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
0.0 0.7 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 0.3 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0 0.5 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
0.0 0.7 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 0.8 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 0.2 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.0 0.4 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.6 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.2 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 0.5 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.0 0.3 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 0.1 REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.0 0.1 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 1.1 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 0.5 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification